Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	deaminase binding	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.20e-06	4	135	3	GO:1990827
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF6 MYO5A MYO1B MYO5C KIF15 SMC3 MYO15A	1.56e-05	118	135	7	GO:0003774
GeneOntologyMolecularFunction	actin filament binding	CACNB2 NRAP MYO5A TRIOBP MYO1B VPS16 MYO5C LRPPRC MYO15A	2.45e-05	227	135	9	GO:0051015
GeneOntologyMolecularFunction	poly(U) RNA binding	HNRNPCL1 PABPC4 HNRNPCL3 HNRNPCL2	7.92e-05	34	135	4	GO:0008266
GeneOntologyMolecularFunction	microfilament motor activity	MYO5A MYO1B MYO5C MYO15A	1.23e-04	38	135	4	GO:0000146
GeneOntologyMolecularFunction	N6-methyladenosine-containing RNA reader activity	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.30e-04	15	135	3	GO:1990247
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	HNRNPCL1 PABPC4 HNRNPCL3 HNRNPCL2	1.37e-04	39	135	4	GO:0008187
GeneOntologyMolecularFunction	damaged DNA binding	SMC6 BLM ZNF782 RPA1 XRCC6	2.64e-04	84	135	5	GO:0003684
GeneOntologyMolecularFunction	pancreatic polypeptide receptor activity	NPY4R2 NPY4R	2.70e-04	4	135	2	GO:0001602
GeneOntologyMolecularFunction	ATP-dependent activity	KIF6 MYO5A ZGRF1 SMC6 MYO1B MYO5C BLM KIF15 SMC3 SMARCA1 HFM1 MYO15A XRCC6	2.74e-04	614	135	13	GO:0140657
GeneOntologyMolecularFunction	single-stranded DNA binding	SMC6 BLM LRPPRC PURB SMARCA1 RPA1	3.02e-04	134	135	6	GO:0003697
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA2D1 CACNB2	4.48e-04	5	135	2	GO:0086007
GeneOntologyMolecularFunction	protein-RNA adaptor activity	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.51e-04	24	135	3	GO:0140517
GeneOntologyMolecularFunction	telomerase RNA binding	HNRNPCL1 HNRNPCL3 HNRNPCL2	6.23e-04	25	135	3	GO:0070034
GeneOntologyMolecularFunction	DNA helicase activity	ZGRF1 BLM HFM1 XRCC6	8.23e-04	62	135	4	GO:0003678
GeneOntologyMolecularFunction	single-stranded RNA binding	A1CF HNRNPCL1 PABPC4 HNRNPCL3 HNRNPCL2	9.47e-04	111	135	5	GO:0003727
GeneOntologyMolecularFunction	actin binding	CACNB2 NRAP MYO5A MYRIP TRIOBP MYO1B VPS16 MYO5C LRPPRC MYO15A	1.57e-03	479	135	10	GO:0003779
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	ZGRF1 BLM SMARCA1 HFM1 XRCC6	1.72e-03	127	135	5	GO:0008094
GeneOntologyBiologicalProcess	negative regulation of mRNA modification	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.29e-06	6	134	3	GO:0090367
GeneOntologyBiologicalProcess	actin filament-based movement	CACNA2D1 CACNB2 MYO5A MYRIP MYO1B MYO5C SCN5A PKP2	7.22e-06	153	134	8	GO:0030048
GeneOntologyBiologicalProcess	regulation of mRNA modification	HNRNPCL1 HNRNPCL3 HNRNPCL2	9.21e-06	7	134	3	GO:0090365
GeneOntologyBiologicalProcess	telomere maintenance	HNRNPCL1 ATR SMC6 HNRNPCL3 BLM RPA1 XRCC6 HNRNPCL2	1.43e-05	168	134	8	GO:0000723
GeneOntologyBiologicalProcess	vesicle transport along actin filament	MYO5A MYRIP MYO5C	2.19e-05	9	134	3	GO:0030050
GeneOntologyBiologicalProcess	mRNA modification	A1CF HNRNPCL1 HNRNPCL3 HNRNPCL2	2.28e-05	26	134	4	GO:0016556
GeneOntologyBiologicalProcess	actin filament-based transport	MYO5A MYRIP MYO5C	4.26e-05	11	134	3	GO:0099515
GeneOntologyBiologicalProcess	telomere organization	HNRNPCL1 ATR SMC6 HNRNPCL3 BLM RPA1 XRCC6 HNRNPCL2	4.81e-05	199	134	8	GO:0032200
GeneOntologyBiologicalProcess	cell-cell signaling involved in cardiac conduction	CACNA2D1 CACNB2 SCN5A PKP2	6.79e-05	34	134	4	GO:0086019
GeneOntologyBiologicalProcess	bundle of His cell to Purkinje myocyte communication	CACNA2D1 SCN5A PKP2	1.15e-04	15	134	3	GO:0086069
GeneOntologyBiologicalProcess	membrane depolarization during atrial cardiac muscle cell action potential	CACNB2 SCN5A	1.25e-04	3	134	2	GO:0098912
GeneOntologyBiologicalProcess	membrane depolarization during bundle of His cell action potential	CACNA2D1 SCN5A	1.25e-04	3	134	2	GO:0086048
GeneOntologyBiologicalProcess	regulation of heart rate by cardiac conduction	CACNA2D1 CACNB2 SCN5A PKP2	1.43e-04	41	134	4	GO:0086091
GeneOntologyBiologicalProcess	telomere maintenance via telomerase	HNRNPCL1 ATR HNRNPCL3 RPA1 HNRNPCL2	1.46e-04	77	134	5	GO:0007004
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	HNRNPCL1 ATR HNRNPCL3 RPA1 HNRNPCL2	2.08e-04	83	134	5	GO:0006278
GeneOntologyBiologicalProcess	telomere maintenance via telomere lengthening	HNRNPCL1 ATR HNRNPCL3 RPA1 HNRNPCL2	3.03e-04	90	134	5	GO:0010833
GeneOntologyBiologicalProcess	regulation of metal ion transport	CACNA2D1 CACNB2 MYO5A CAPN3 RGS9 CCKAR PTK2B SERPINE2 KCNJ1 SCN5A PKP2	3.81e-04	493	134	11	GO:0010959
GeneOntologyBiologicalProcess	negative regulation of catabolic process	A1CF HNRNPCL1 HNRNPCL3 LRPPRC SENP1 SERPINE2 NAMPT SMCR8 HNRNPCL2 ANKS1A	4.11e-04	418	134	10	GO:0009895
GeneOntologyBiologicalProcess	epoxide metabolic process	EPHX1 EPHX2	4.14e-04	5	134	2	GO:0097176
GeneOntologyBiologicalProcess	positive regulation of high voltage-gated calcium channel activity	CACNA2D1 CACNB2	4.14e-04	5	134	2	GO:1901843
GeneOntologyBiologicalProcess	membrane depolarization during cardiac muscle cell action potential	CACNA2D1 CACNB2 SCN5A	4.32e-04	23	134	3	GO:0086012
GeneOntologyCellularComponent	nucleoplasmic periphery of the nuclear pore complex	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.19e-06	6	135	3	GO:1990826
GeneOntologyCellularComponent	pronucleus	HNRNPCL1 HNRNPCL3 BLM HNRNPCL2	3.02e-05	28	135	4	GO:0045120
GeneOntologyCellularComponent	presynapse	RPL24 CACNA2D1 CACNB2 ATR MYO5A ITSN1 GRIK2 RGS9 VPS16 CCKAR MADD PTK2B SENP1 CLTA IQSEC1 RAB7A SMCR8	5.82e-05	886	135	17	GO:0098793
GeneOntologyCellularComponent	lateral element	BLM SMC3 RPA1	2.37e-04	19	135	3	GO:0000800
GeneOntologyCellularComponent	catalytic step 2 spliceosome	HNRNPCL1 PRPF8 HNRNPCL3 CRNKL1 HNRNPCL2	4.18e-04	97	135	5	GO:0071013
GeneOntologyCellularComponent	telomerase holoenzyme complex	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.46e-04	25	135	3	GO:0005697
GeneOntologyCellularComponent	myosin complex	MYO5A MYO1B MYO5C MYO15A	5.75e-04	59	135	4	GO:0016459
Domain	IQ_motif_EF-hand-BS	MYO5A MYO1B MYO5C ADGB SCN5A IQSEC1 MYO15A	3.62e-06	90	133	7	IPR000048
Domain	IQ	MYO5A MYO1B MYO5C ADGB SCN5A IQSEC1 MYO15A	4.51e-06	93	133	7	PS50096
Domain	hnRNP_C	HNRNPCL1 HNRNPCL4 HNRNPCL2	6.95e-06	6	133	3	IPR017347
Domain	IQ	MYO5A MYO1B MYO5C ADGB SCN5A MYO15A	2.44e-05	81	133	6	SM00015
Domain	NPY4_rcpt	NPY4R2 NPY4R	5.03e-05	2	133	2	IPR001933
Domain	ETV3	ETV3 ETV3L	5.03e-05	2	133	2	IPR032929
Domain	Myosin_head_motor_dom	MYO5A MYO1B MYO5C MYO15A	1.50e-04	38	133	4	IPR001609
Domain	MYOSIN_MOTOR	MYO5A MYO1B MYO5C MYO15A	1.50e-04	38	133	4	PS51456
Domain	Myosin_head	MYO5A MYO1B MYO5C MYO15A	1.50e-04	38	133	4	PF00063
Domain	MYSc	MYO5A MYO1B MYO5C MYO15A	1.50e-04	38	133	4	SM00242
Domain	IQ	MYO5A MYO1B MYO5C IQSEC1 MYO15A	1.52e-04	71	133	5	PF00612
Domain	FG_GAP	CRTAC1 ITGA4 ITGAE	4.92e-04	22	133	3	PS51470
Domain	Myosin_S1_N	MYO5A MYO5C	4.96e-04	5	133	2	IPR008989
Domain	FG-GAP	CRTAC1 ITGA4 ITGAE	6.40e-04	24	133	3	PF01839
Domain	FG-GAP	CRTAC1 ITGA4 ITGAE	6.40e-04	24	133	3	IPR013517
Domain	-	ATR NAPG CRNKL1 LRPPRC TTC23 TTC29 EMC2	7.11e-04	207	133	7	1.25.40.10
Domain	Dilute_dom	MYO5A MYO5C	7.41e-04	6	133	2	IPR002710
Domain	PH_BEACH	NBEAL1 LYST	7.41e-04	6	133	2	PF14844
Domain	DIL	MYO5A MYO5C	7.41e-04	6	133	2	PF01843
Domain	DILUTE	MYO5A MYO5C	7.41e-04	6	133	2	PS51126
Domain	DIL	MYO5A MYO5C	7.41e-04	6	133	2	SM01132
Domain	P-loop_NTPase	CACNB2 KIF6 MYO5A ZGRF1 SMC6 MYO1B MYO5C BLM KIF15 SMC3 SMARCA1 RAB7A HFM1 MYO15A HS3ST2	1.05e-03	848	133	15	IPR027417
Domain	PH-BEACH_dom	NBEAL1 LYST	1.37e-03	8	133	2	IPR023362
Domain	-	NBEAL1 LYST	1.37e-03	8	133	2	2.30.29.40
Domain	Epox_hydrolase-like	EPHX1 EPHX2	1.37e-03	8	133	2	IPR000639
Domain	RecF/RecN/SMC_N	SMC6 SMC3	1.37e-03	8	133	2	IPR003395
Domain	PH_BEACH	NBEAL1 LYST	1.37e-03	8	133	2	PS51783
Domain	SMC_N	SMC6 SMC3	1.37e-03	8	133	2	PF02463
Domain	TPR-like_helical_dom	ATR NAPG CRNKL1 LRPPRC TTC23 TTC29 EMC2	1.41e-03	233	133	7	IPR011990
Domain	BEACH	NBEAL1 LYST	1.75e-03	9	133	2	PS50197
Domain	Beach	NBEAL1 LYST	1.75e-03	9	133	2	PF02138
Domain	-	NBEAL1 LYST	1.75e-03	9	133	2	1.10.1540.10
Domain	Beach	NBEAL1 LYST	1.75e-03	9	133	2	SM01026
Domain	BEACH_dom	NBEAL1 LYST	1.75e-03	9	133	2	IPR000409
Domain	NPY_rcpt	NPY4R2 NPY4R	1.75e-03	9	133	2	IPR000611
Domain	Integrin_alpha	ITGA4 ITGAE	2.65e-03	11	133	2	PF00357
Domain	PH_dom-like	NBEAL1 SH3BP2 ITSN1 TRIOBP MYO1B LYST PTK2B IQSEC1 ANKS1A	3.47e-03	426	133	9	IPR011993
Domain	RRM_1	A1CF HNRNPCL1 REXO5 PABPC4 HNRNPCL4 HNRNPCL2	3.77e-03	208	133	6	PF00076
Domain	RRM	A1CF HNRNPCL1 REXO5 PABPC4 HNRNPCL4 HNRNPCL2	4.64e-03	217	133	6	SM00360
Domain	Peptidase_C2	CAPN3 ADGB	4.97e-03	15	133	2	PF00648
Domain	CysPc	CAPN3 ADGB	4.97e-03	15	133	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN3 ADGB	4.97e-03	15	133	2	IPR001300
Domain	CALPAIN_CAT	CAPN3 ADGB	4.97e-03	15	133	2	PS50203
Domain	Integrin_alpha_C_CS	ITGA4 ITGAE	5.66e-03	16	133	2	IPR018184
Domain	RRM_dom	A1CF HNRNPCL1 REXO5 PABPC4 HNRNPCL4 HNRNPCL2	5.76e-03	227	133	6	IPR000504
Domain	RRM	A1CF HNRNPCL1 REXO5 PABPC4 HNRNPCL4 HNRNPCL2	6.13e-03	230	133	6	PS50102
Pathway	REACTOME_SUMOYLATION	HNRNPCL1 SMC6 HNRNPCL3 BLM SENP1 SMC3 RPA1 HNRNPCL2	3.76e-05	169	105	8	MM14919
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RPL24 HNRNPCL1 MYO5A PABPC4 LARS1 MYO1B PRPF8 MYO5C HNRNPCL3 CRNKL1 LRPPRC SENP1 SMC3 CLTA PKP2 HNRNPCL4 RPA1 XRCC6 HNRNPCL2	6.04e-09	949	136	19	36574265
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA2D1 CACNB2 MYO5A ITSN1 TRIOBP GRIK2 SLC1A3 LRPPRC SENP1 KIF15 KCNJ1 MORF4L1 PURB ZBTB21 IQSEC1 RAB7A RPA1 XRCC6 ANKS1A	7.64e-09	963	136	19	28671696
Pubmed	Human transcription factor protein interaction networks.	RPL24 LIMD1 MYO5A PABPC4 LARS1 ETV3 MYO1B MYO5C ZNF3 BLM LIPT1 SUGP2 SMC3 MORF4L1 PURB ZBTB21 SMARCA1 RAB7A SCAF11 ZNF107 RPA1 XRCC6 XPOT	8.11e-09	1429	136	23	35140242
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	HNRNPCL1 WASHC4 ATR PABPC4 MYO1B PRPF8 BLM SMC3 PURB RAB7A RPA1 XRCC6	1.08e-08	340	136	12	24332808
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	RPL24 ATR PABPC4 LARS1 MYO1B PRPF8 CRNKL1 LRPPRC SUGP2 SMC3 SCN5A PKP2 XRCC6	5.41e-08	477	136	13	31300519
Pubmed	High prevalence of genetic variants previously associated with Brugada syndrome in new exome data.	CACNA2D1 CACNB2 SCN5A	5.85e-08	3	136	3	23414114
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL24 WASHC4 MYO5A LARS1 MYO1B VPS16 IDH3B PRPF8 BLM CRNKL1 LRPPRC NAMPT SUGP2 SMC3 SMARCA1 IQSEC1 PKP2 RAB7A RPA1 XRCC6 XPOT	7.22e-08	1353	136	21	29467282
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CACNA2D1 MYO5A PABPC4 LARS1 MYO1B IDH3B PRPF8 MYO5C CRNKL1 LRPPRC SUGP2 SMC3 CLTA ZBTB21 RAB7A EMC2 RPA1 XRCC6	1.11e-07	1024	136	18	24711643
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RPL24 CACNA2D1 CACNB2 HNRNPCL1 MYO5A ITSN1 PABPC4 LARS1 IDH3B SLC1A3 MADD HNRNPCL3 PTK2B LRPPRC PTPRA SUGP2 PURB IQSEC1 RAB7A SIPA1L2 HNRNPCL2	1.84e-07	1431	136	21	37142655
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CACNA2D1 PABPC4 LARS1 NAPG TRIOBP IRF2 MYO1B IDH3B PRPF8 SORT1 LRPPRC LIPT1 NAMPT PURB CLTA EMC2 SLC30A9 RPA1 PLOD2 XRCC6 XPOT	2.03e-07	1440	136	21	30833792
Pubmed	The splicing factor hnRNP C regulates expression of co-stimulatory molecules CD80 and CD40 in dendritic cells.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.33e-07	4	136	3	23831410
Pubmed	hnRNPC induces isoform shifts in miR-21-5p leading to cancer development.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.33e-07	4	136	3	35729324
Pubmed	N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.33e-07	4	136	3	36681355
Pubmed	hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.33e-07	4	136	3	10805751
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	A1CF PABPC4 MED31 MYO1B PRPF8 CRNKL1 NAMPT SUGP2 PHF3 PURB CLTA SMARCA1 IQSEC1 PKP2 RAB7A SCAF11 C5 RPA1 PLOD2 XRCC6	4.08e-07	1371	136	20	36244648
Pubmed	Heterogeneous nuclear ribonucleoprotein C1 may control miR-30d levels in endometrial exosomes affecting early embryo implantation.	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.82e-07	5	136	3	29846695
Pubmed	Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene.	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.82e-07	5	136	3	9128719
Pubmed	Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism.	HNRNPCL1 HNRNPCL3 HNRNPCL2	5.82e-07	5	136	3	25809670
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EPHX1 RPL24 ATR PABPC4 SMC6 LARS1 MYO1B IDH3B PRPF8 CRNKL1 LRPPRC NAMPT SMC3 CLTA SMARCA1 RAB7A EMC2 RPA1 XRCC6 XPOT	7.45e-07	1425	136	20	30948266
Pubmed	Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.16e-06	6	136	3	26048669
Pubmed	Selective disruption of genes expressed in totipotent embryonal stem cells.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.16e-06	6	136	3	1317320
Pubmed	Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.16e-06	6	136	3	15687492
Pubmed	Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.16e-06	6	136	3	18363099
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	A1CF HNRNPCL1 REXO5 PABPC4 PRPF8 HNRNPCL3 CRNKL1 LRPPRC HNRNPCL2 BRWD1	1.20e-06	347	136	10	16033648
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RPL24 LARS1 IDH3B PRPF8 CRNKL1 LRPPRC NAMPT SUGP2 SMC3 RAB7A RPA1 XRCC6 XPOT	1.45e-06	638	136	13	33239621
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.02e-06	7	136	3	25846207
Pubmed	Exploring the link between MORF4L1 and risk of breast cancer.	ATR BLM MORF4L1 RPA1	2.24e-06	24	136	4	21466675
Pubmed	Brugada Syndrome	CACNA2D1 CACNB2 SCN5A PKP2	2.24e-06	24	136	4	20301690
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EPHX1 RPL24 PABPC4 LARS1 MYO1B LRPPRC SMC3 PKP2 RAB7A RPA1 SMCR8 XRCC6 ANKS1A	4.52e-06	708	136	13	39231216
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	RPL24 MYO1B VPS16 IDH3B PRPF8 LRPPRC NAMPT SUGP2 CLTA SMARCA1 SCAF11 XPOT	4.61e-06	601	136	12	33658012
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	HNRNPCL1 PABPC4 PRPF8 LRPPRC SUGP2 SMC3	4.66e-06	109	136	6	29511296
Pubmed	Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization.	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.83e-06	9	136	3	10452948
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	RPL24 MED31 SENP1 SUGP2 SMC3 ZBTB21 SMARCA1 VRTN RAB7A XRCC6	5.40e-06	411	136	10	35182466
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EPHX1 RPL24 HNRNPCL1 TRIOBP MYO1B PRPF8 BLM CRNKL1 LRPPRC SUGP2 MORF4L1 IQSEC1 RAB7A SIPA1L2 XRCC6 HCRTR1	5.48e-06	1082	136	16	38697112
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	EPHX1 EPHX2 ATR CAPN3 ITGA4 ITGAE XRCC6	7.10e-06	179	136	7	19074885
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RPL24 MYO1B IDH3B PRPF8 BLM LRPPRC SUGP2 SMC3 PHF3 MORF4L1 RAB7A SCAF11 NUDCD1 RPA1 XRCC6	8.15e-06	989	136	15	36424410
Pubmed	Network organization of the human autophagy system.	LARS1 NAPG LRPPRC NAMPT PTPRA SMC3 CLTA RPA1 SMCR8 XPOT	9.21e-06	437	136	10	20562859
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYO5A PABPC4 MYO1B PRPF8 BLM CRNKL1 LRPPRC SUGP2 PHF3 SCAF11 XRCC6 XPOT	1.06e-05	653	136	12	22586326
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WASHC4 MYO5A ITSN1 LARS1 MYRIP TRIOBP CRTAC1 PRPF8 MADD CRNKL1 SERPINE2 PTPRA MORF4L1 ZNF439 XRCC6 XPOT BRWD1	1.17e-05	1285	136	17	35914814
Pubmed	Interaction between nucleosome assembly protein 1-like family members.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.25e-05	12	136	3	21333655
Pubmed	The biogenesis of the coiled body during early mouse development.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.25e-05	12	136	3	7768196
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GABRG1 HNRNPCL1 MYO5A ITSN1 PABPC4 MYRIP MYO1B PRPF8 TEX35 LYST HNRNPCL3 LRPPRC ZBTB21 SMARCA1 EMC2 SIPA1L2 XRCC6 HNRNPCL2	1.39e-05	1442	136	18	35575683
Pubmed	Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression.	EPHX2 PTK2B	1.52e-05	2	136	2	36470481
Pubmed	Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.	EPHX1 EPHX2	1.52e-05	2	136	2	29298899
Pubmed	Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase.	EPHX1 EPHX2	1.52e-05	2	136	2	18513744
Pubmed	Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.	CACNB2 A1CF	1.52e-05	2	136	2	21357697
Pubmed	Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay.	CACNB2 SCN5A	1.52e-05	2	136	2	22090166
Pubmed	Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson's disease.	EPHX1 EPHX2	1.52e-05	2	136	2	11692079
Pubmed	ATR prohibits replication catastrophe by preventing global exhaustion of RPA.	ATR RPA1	1.52e-05	2	136	2	24267891
Pubmed	BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation.	BLM RPA1	1.52e-05	2	136	2	19165145
Pubmed	Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome.	CACNB2 SCN5A	1.52e-05	2	136	2	20025708
Pubmed	Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest.	ATR BLM	1.52e-05	2	136	2	14729972
Pubmed	Genetic variants in epoxide hydrolases modify the risk of oligozoospermia and asthenospermia in Han-Chinese population.	EPHX1 EPHX2	1.52e-05	2	136	2	22986331
Pubmed	Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia.	EPHX1 EPHX2	1.52e-05	2	136	2	18369166
Pubmed	Human myosin-Vc is a novel class V myosin expressed in epithelial cells.	MYO5A MYO5C	1.52e-05	2	136	2	11870218
Pubmed	In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.	ATR RPA1	1.52e-05	2	136	2	22948311
Pubmed	The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.	EPHX1 EPHX2	1.52e-05	2	136	2	33374956
Pubmed	FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.	A1CF FAM210A	1.52e-05	2	136	2	37522353
Pubmed	Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury.	EPHX1 EPHX2	1.52e-05	2	136	2	33567578
Pubmed	Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.	MYO5A MYO5C	1.52e-05	2	136	2	26912658
Pubmed	Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly.	CACNA2D1 CACNB2	1.52e-05	2	136	2	8107964
Pubmed	Cloning of the beta(2a) subunit of the voltage-dependent calcium channel from human heart: cooperative effect of alpha(2)/delta and beta(2a) on the membrane expression of the alpha(1C) subunit.	CACNA2D1 CACNB2	1.52e-05	2	136	2	10623591
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	HNRNPCL1 PRPF8 HNRNPCL3 SMC3 XRCC6 HNRNPCL2	1.59e-05	135	136	6	31077711
Pubmed	Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication.	PABPC4 RPA1 XRCC6	1.63e-05	13	136	3	18305033
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	EPHX1 RPL24 MYO5A PABPC4 MYO1B IDH3B PRPF8 LRPPRC SMC3 CLTA SMARCA1 RAB7A XRCC6	1.72e-05	803	136	13	36517590
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO5A MYO1B MYO5C	2.06e-05	14	136	3	8022818
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	RPL24 PABPC4 PRPF8 BLM NAMPT PURB RPA1 XRCC6 XPOT	2.12e-05	383	136	9	29331416
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	PABPC4 LARS1 BLM LRPPRC PURB SNX18 SCAF11 RPA1 XRCC6	2.65e-05	394	136	9	27248496
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	PRPF8 CRNKL1 SUGP2 SMC3 RPA1 XRCC6 XPOT	2.69e-05	220	136	7	35785414
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SMC6 BLM SMC3 PHF3 MORF4L1 ZBTB21 SMARCA1 SCAF11 RPA1 XRCC6 BRWD1	2.89e-05	608	136	11	36089195
Pubmed	Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.	RPL24 HNRNPCL1 IDH3B PRPF8 LRPPRC XPOT	2.99e-05	151	136	6	18457437
Pubmed	Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis.	MED31 BLM RPA1	3.16e-05	16	136	3	17696610
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RPL24 MYO5A PABPC4 LARS1 MYO1B ITGA4 PRPF8 CRNKL1 LRPPRC SMC3 PHF3 PURB SMARCA1 PKP2 SCAF11 XRCC6	3.44e-05	1257	136	16	36526897
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	EPHX1 EPHX2 CACNA2D1 LARS1 LAMA4 IDH3B HIBADH LRPPRC PKP2 RAB7A ZNF782 EMC2 XRCC6	3.45e-05	859	136	13	31536960
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	RPL24 PABPC4 PRPF8 SLC1A3 LRPPRC NAMPT RAB7A EMC2 XPOT	3.48e-05	408	136	9	33766124
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	RPL24 MYO5A ITSN1 PTK2B PURB IQSEC1 BRWD1	3.68e-05	231	136	7	16452087
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	RPL24 MYO5A ITSN1 PABPC4 MYO1B PRPF8 LRPPRC CLTA PKP2 RPA1 XRCC6	3.76e-05	626	136	11	33644029
Pubmed	A method to identify cDNAs based on localization of green fluorescent protein fusion products.	HNRNPCL1 HNRNPCL3 HNRNPCL2	3.82e-05	17	136	3	10716735
Pubmed	Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.	HNRNPCL1 HNRNPCL3 SMC3 HNRNPCL2	4.13e-05	49	136	4	27352031
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RPL24 MYO5A TRIOBP SLC1A3 MADD LRPPRC SERPINE2 NAMPT SUGP2 PURB CLTA IQSEC1 RAB7A EMC2 SIPA1L2	4.18e-05	1139	136	15	36417873
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	EPHX1 LARS1 PRPF8 SMC3 RAB7A EMC2 RPA1 PLOD2 XRCC6	4.51e-05	422	136	9	27342126
Pubmed	Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity.	BLM RPA1	4.54e-05	3	136	2	10825162
Pubmed	Chromosomal mapping and expression levels of a mouse soluble epoxide hydrolase gene.	EPHX1 EPHX2	4.54e-05	3	136	2	7915936
Pubmed	Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium.	A1CF LIPT1	4.54e-05	3	136	2	23077570
Pubmed	MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.	MYO5A MYRIP	4.54e-05	3	136	2	22993210
Pubmed	Identification of ITGA4/ITGB7 and ITGAE/ITGB7 expressing subsets of decidual dendritic-like cells within distinct microdomains of the pregnant mouse uterus.	ITGA4 ITGAE	4.54e-05	3	136	2	18562709
Pubmed	Pseudoexfoliation and Alzheimer's associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression.	EPHX2 PTK2B	4.54e-05	3	136	2	28973302
Pubmed	Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.	CACNA2D1 CACNB2	4.54e-05	3	136	2	17224476
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5C	4.54e-05	3	136	2	24339992
Pubmed	Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function.	EPHX1 EPHX2	4.54e-05	3	136	2	33334892
Pubmed	Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a +/ΔKPQ Mice.	A1CF SCN5A	4.54e-05	3	136	2	34248669
Pubmed	Intramanchette transport during primate spermiogenesis: expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis.	MYO5A MYRIP	4.54e-05	3	136	2	18478159
Pubmed	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.	NPY4R2 NPY4R	4.54e-05	3	136	2	8643460
Pubmed	Blockade of αEβ7 integrin suppresses accumulation of CD8+ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo.	ITGA4 ITGAE	4.54e-05	3	136	2	27543429
Pubmed	Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.	CACNA2D1 CACNB2	4.54e-05	3	136	2	20817017
Pubmed	Functional properties of the CaV1.2 calcium channel activated by calmodulin in the absence of alpha2delta subunits.	CACNA2D1 CACNB2	4.54e-05	3	136	2	19106618
Pubmed	Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism.	EPHX1 EPHX2	4.54e-05	3	136	2	19540314
Pubmed	Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells.	MYO5A MYRIP	4.54e-05	3	136	2	21740491
Pubmed	A Shld1-controlled POT1a provides support for repression of ATR signaling at telomeres through RPA exclusion.	ATR RPA1	4.54e-05	3	136	2	21070964
Pubmed	Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport.	MYO5A MYRIP	4.54e-05	3	136	2	19317802
Interaction	CLEC4E interactions	MYO5A LARS1 MYO1B NAMPT PURB CLTA PKP2 RAB7A EMC2 SLC30A9 RPA1 SMCR8	4.30e-06	353	134	12	int:CLEC4E
GeneFamily	Myosins, class V	MYO5A MYO5C	9.98e-05	3	105	2	1100
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC6 SMC3	6.88e-04	7	105	2	761
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 LYST	1.17e-03	9	105	2	1230
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA2D1 CACNB2 NRAP SLC1A3 SORT1 SCN5A PKP2	2.19e-06	193	136	7	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3BP2 ITSN1 NAPG ITGA4 KCNJ1 ADGRE4P	8.87e-06	157	136	6	0ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCell	facs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3BP2 ITSN1 NAPG ITGA4 KCNJ1 ADGRE4P	8.87e-06	157	136	6	fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EPHX1 CAPN3 ITGA4 BMP1 PTK2B DYRK3	1.02e-05	161	136	6	e3327c296d48e821004e61a573abb75624a6f040
ToppCell	(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts\|(0)_Normal/No_Treatment / Stress and Cell class	GPX3 MYO1B JAM2 BMP1 SERPINE2 PLOD2	1.54e-05	173	136	6	c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPN ZGRF1 BLM KIF15 SMC3 RPA1	1.59e-05	174	136	6	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CACNA2D1 CAPN3 LAMA4 CRTAC1 SERPINE2 TET1	1.64e-05	175	136	6	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 CACNA2D1 GPX3 LAMA4 ADAMTSL3 BMP1	1.70e-05	176	136	6	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 CACNA2D1 GPX3 LAMA4 ADAMTSL3 BMP1	1.70e-05	176	136	6	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHX2 MYO1B RGS9 MYO5C SERPINE2 FGL1	1.87e-05	179	136	6	7aa4137f672dadb3be92009cde6e0ea60a15372d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO1B GRIK2 SCN5A PKP2 SIPA1L2 HCRTR1	1.87e-05	179	136	6	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage\|lymph-node_spleen / Manually curated celltypes from each tissue	EPHX1 NRAP CAPN3 GPX3 SLC1A3 HS3ST2	1.87e-05	179	136	6	b4430f633711cecf793e8e76e766a66ff1eff473
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 CACNB2 NRAP SLC1A3 SCN5A PKP2	1.99e-05	181	136	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 CACNB2 GPX3 MYO1B SLC1A3 SERPINE2	2.05e-05	182	136	6	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 CACNB2 GPX3 MYO1B SLC1A3 SERPINE2	2.05e-05	182	136	6	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 CACNB2 NRAP SLC1A3 SCN5A PKP2	2.25e-05	185	136	6	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	3beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA2D1 CACNB2 GPX3 LAMA4 ADAMTSL3 SERPINE2	2.25e-05	185	136	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	9aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	42939b294ea3e871274d8b73124c850dc1904fd2
ToppCell	Severe_COVID-19-Myeloid-transitional_Macro\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EPHX1 MYO5A PABPC4 GPX3 TPCN1 CCDC63	2.25e-05	185	136	6	7a3612520ae4f0cd61480eadba31eecce001419d
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SH3BP2 ITSN1 GPX3 SLC1A3 BMP1 PURB	2.32e-05	186	136	6	3314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA2D1 GPX3 LAMA4 MYO1B SLC1A3 SERPINE2	2.54e-05	189	136	6	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA2D1 GPX3 LAMA4 MYO1B SLC1A3 SERPINE2	2.61e-05	190	136	6	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	droplet-Lung-nan-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 GPX3 LAMA4 MYO1B SLC1A3 SERPINE2	2.77e-05	192	136	6	df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-RG\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FAM210A GPX3 SERPINE2 NAMPT PLOD2 XPOT	2.77e-05	192	136	6	ee822325bb32ac7ad1eeccc23d966367e90a9edd
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	EPHX2 GPX3 LAMA4 SERPINE2 SMARCA1 EMC2	2.85e-05	193	136	6	f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA2D1 GPX3 LAMA4 MYO1B SLC1A3 SERPINE2	2.85e-05	193	136	6	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA2D1 GPX3 LAMA4 MYO1B SLC1A3 SERPINE2	2.85e-05	193	136	6	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO5A ITSN1 SLC1A3 MGAT1 HS3ST2 ANKS1A	2.94e-05	194	136	6	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO5A ITSN1 SLC1A3 MGAT1 HS3ST2 ANKS1A	3.02e-05	195	136	6	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHX2 CACNA2D1 B3GALT5 MYO1B ADGRG7 C5	3.02e-05	195	136	6	e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-RG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	EPHX2 FAM210A GPX3 SERPINE2 NAMPT PLOD2	3.11e-05	196	136	6	e77461ab0f909c1d22965d99f251da49f03cbb8f
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO5A ITSN1 PABPC4 SLC1A3 MGAT1 NAMPT	3.20e-05	197	136	6	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO5A ITSN1 PABPC4 SLC1A3 MGAT1 NAMPT	3.20e-05	197	136	6	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZGRF1 BLM ADGRG7 KIF15 MYO15A ZNF681	3.29e-05	198	136	6	d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MYO1B ITGA4 SLC1A3 PTK2B SERPINE2 CA4	3.48e-05	200	136	6	6ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MYO1B ITGA4 SLC1A3 PTK2B SERPINE2 CA4	3.48e-05	200	136	6	081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MYO1B ITGA4 SLC1A3 PTK2B SERPINE2 CA4	3.48e-05	200	136	6	66e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCell	normal_Lung-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	GPX3 MYRIP LYST JAM2 SERPINE2 NAMPT	3.48e-05	200	136	6	413ac64bbe95b8c921c5396d8b5f298fec8c4f82
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Macroglial-Glia_progenitor_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	FAM210A GPX3 JAM2 NAMPT PLOD2 XPOT	3.48e-05	200	136	6	1e1f4341b6dc17478a1cb8f625732e3008c2ec8a
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MYO1B ITGA4 SLC1A3 PTK2B SERPINE2 CA4	3.48e-05	200	136	6	940892bea41fde567f138a896d151acccef03a6a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Glia_progenitor_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	FAM210A GPX3 SERPINE2 NAMPT TET1 PLOD2	3.48e-05	200	136	6	c5afba198818d02b4e79956edd7e77ebff74fc2e
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EPHX2 GPX3 LAMA4 RGS9 PTGDR	4.11e-05	125	136	5	d05556ea185c15815a4f8643f1c01185badbeece
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	CACNA2D1 PNLIP RGS9 ETV3L SERPINE2	6.81e-05	139	136	5	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIK2 PTGDR ADAMTSL3 KCNJ1 HS3ST2	9.16e-05	148	136	5	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 PTGDR ADGB FGL1 ZNF681	1.14e-04	155	136	5	51f6447945389649d99dcf7603b396195c631ead
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 PTGDR ADGB FGL1 ZNF681	1.14e-04	155	136	5	23dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GPX3 HIBADH CCKAR CA4	1.53e-04	165	136	5	906321cb5f299d77436fb5540fd8c52d7532beca
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GPX3 HIBADH CCKAR CA4	1.53e-04	165	136	5	02a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPN ZGRF1 KIF15 HACE1 RPA1	1.57e-04	166	136	5	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	facs-Kidney-nan-24m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 PNLIP GPX3 HIBADH CA4	1.57e-04	166	136	5	fe87b444fc0ef6fc20c646c9d2c3c8ce916a70c0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MED31 TATDN2 SLC1A3 JAM2 PKP2	1.61e-04	167	136	5	9b9b4cad0b35d121256176600ea4705759c105d3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 CENPN ZGRF1 BLM KIF15	1.71e-04	169	136	5	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 CACNA2D1 LAMA4 ADAMTSL3 SNX18	1.71e-04	169	136	5	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 ZGRF1 WNT9A BLM C5	1.71e-04	169	136	5	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	WASHC4 MYO1B TPCN1 BMP1 ANKS1A	1.75e-04	170	136	5	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 NRAP SLC1A3 SCN5A PKP2	1.75e-04	170	136	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KIF6 GRIK2 SCN5A PKP2 CA4	1.75e-04	170	136	5	14aa86a4f526ed6986afcb28c49225522055550c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PABPC4 SLC1A3 CCKAR MYO5C	1.90e-04	173	136	5	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PABPC4 SLC1A3 CCKAR MYO5C	1.90e-04	173	136	5	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	MYO5A GPX3 GRIK2 SIPA1L2 HS3ST2	1.90e-04	173	136	5	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 CENPN BLM ADGB KIF15	1.95e-04	174	136	5	84da9faff088d05233183b425385beb054c92d1b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KIF6 GRIK2 SCN5A PKP2 CA4	2.06e-04	176	136	5	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 NRAP SORT1 SCN5A PKP2	2.06e-04	176	136	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	PNLIP GPX3 MYRIP LYST NAMPT	2.23e-04	179	136	5	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPN GRIK2 RGS9 KIF15 CA4	2.23e-04	179	136	5	327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCell	RV\|World / Chamber and Cluster_Paper	CACNB2 NRAP LAMA4 TPCN1 PKP2	2.34e-04	181	136	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CACNA2D1 ITSN1 B3GALT5 SUGP2 RPA1	2.47e-04	183	136	5	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO1B ITGA4 PTK2B SERPINE2 CA4	2.47e-04	183	136	5	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Thalamus / BrainAtlas - Mouse McCarroll V32	WNT9A MYO5C PTK2B PKP2	2.50e-04	100	136	4	20675fc2ffc5ab63047d38da083b50d470f3db19
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	WNT9A MYO5C PTK2B PKP2	2.50e-04	100	136	4	1de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora\|Thalamus / BrainAtlas - Mouse McCarroll V32	WNT9A MYO5C PTK2B PKP2	2.50e-04	100	136	4	ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCell	droplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 MYO1B SLC1A3 SERPINE2 PLOD2	2.53e-04	184	136	5	89ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF6 MYO1B ADAMTSL3 SCN5A SMARCA1	2.53e-04	184	136	5	55dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CACNA2D1 LZTR1 WNT9A PTK2B HS3ST2	2.53e-04	184	136	5	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF6 MYO1B ADAMTSL3 SCN5A SMARCA1	2.53e-04	184	136	5	7128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF6 MYO1B ADAMTSL3 SCN5A SMARCA1	2.53e-04	184	136	5	d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO1B ITGA4 PTK2B SERPINE2 CA4	2.53e-04	184	136	5	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	CACNA2D1 CACNB2 NRAP SLC1A3 PKP2	2.53e-04	184	136	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 MYO1B SLC1A3 SERPINE2 PLOD2	2.53e-04	184	136	5	4df6027fa635996c1eddb920f88a5265772df1cd
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNB2 NRAP SLC1A3 SCN5A PKP2	2.53e-04	184	136	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL24 SMC6 ITGA4 LYST BRWD1	2.66e-04	186	136	5	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A1CF GPX3 MYO1B SERPINE2 SMARCA1	2.66e-04	186	136	5	4bb54043f944a979db91bde9a86dd66f498c7658
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYRIP CRTAC1 LYST JAM2 SERPINE2	2.66e-04	186	136	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	IDH3B SLC1A3 BMP1 SERPINE2 PURB	2.66e-04	186	136	5	701eea0016d69f0f9d29b613948f91239096e6c7
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-\|lymph-node_spleen / Manually curated celltypes from each tissue	ITGA4 PTGDR LYST SERPINE2 SUGP2	2.72e-04	187	136	5	9000241566f48e435db9409b7255db68b68f6059
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHX2 ELP6 CRTAC1 GRIK2 BLM	2.72e-04	187	136	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 ZGRF1 GRIK2 BLM KIF15	2.72e-04	187	136	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 LAMA4 MYO1B ADAMTSL3 SERPINE2	2.72e-04	187	136	5	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 NRAP SCN5A PKP2 CCDC63	2.79e-04	188	136	5	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP CAPN3 HIBADH MGAT1 XRCC6	2.79e-04	188	136	5	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 NRAP SCN5A PKP2 CCDC63	2.79e-04	188	136	5	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	SH3BP2 ITGA4 LYST PTK2B NAMPT	2.86e-04	189	136	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP WASHC4 SLC1A3 SERPINE2 SNX18	2.86e-04	189	136	5	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	IPF-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	LIMD1 ITGA4 LYST NAMPT SNX18	2.86e-04	189	136	5	5c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CACNA2D1 CACNB2 GPX3 MYO1B SERPINE2	2.86e-04	189	136	5	dc5164591dea45b420798b94dda211be03daa70c
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A	CACNB2 SH3BP2 ITSN1 TPCN1 SUGP2 PHF3 KCNJ1 IQSEC1 C5 DYRK3	2.51e-07	197	133	10	2558_DN
Drug	2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A	CACNB2 LZTR1 SH3BP2 TRIOBP BMP1 SERPINE2 PTPRA SUGP2	1.90e-05	194	133	8	3570_DN
Drug	Cotinine (-) [486-56-6]; Up 200; 22.6uM; HL60; HG-U133A	ATR MYO5A SH3BP2 ITSN1 LAMA4 IRF2 BMP1 PHF3	2.36e-05	200	133	8	2011_UP
Drug	benz(a)anthracene-5,6-imine	EPHX1 EPHX2	3.39e-05	2	133	2	CID000051305
Drug	AC1L26S0	EPHX1 EPHX2	3.39e-05	2	133	2	CID000015863
Drug	ethylphenylepoxygeranyl ether	EPHX1 EPHX2	3.39e-05	2	133	2	ctd:C100167
Drug	1-methylcyclohexene oxide	EPHX1 EPHX2	3.39e-05	2	133	2	CID000224243
Drug	Cyclodecene (z)	EPHX1 EPHX2	3.39e-05	2	133	2	CID000013633
Drug	benz(a)anthracene-5,6-oxide	EPHX1 EPHX2	3.39e-05	2	133	2	CID000182424
Drug	desyl chloride	EPHX1 EPHX2	3.39e-05	2	133	2	CID000095343
Drug	9,12,13-Todea	EPHX1 EPHX2	3.39e-05	2	133	2	CID005282966
Drug	3-methylcholanthrene-11,12-oxide	EPHX1 EPHX2	3.39e-05	2	133	2	CID000105086
Drug	CdTe	BMP1 CRNKL1 TET1	4.13e-05	12	133	3	CID000091501
Disease	Brugada Syndrome 1	CACNA2D1 CACNB2 SCN5A PKP2	2.57e-07	13	131	4	C4551804
Disease	Brugada Syndrome (disorder)	CACNA2D1 CACNB2 SCN5A PKP2	3.68e-06	24	131	4	C1142166
Disease	Other specified cardiac arrhythmias	CACNA2D1 CACNB2 PKP2	1.37e-05	11	131	3	C0348626
Disease	Nodal rhythm disorder	CACNA2D1 CACNB2 PKP2	1.37e-05	11	131	3	C0264893
Disease	Ectopic rhythm	CACNA2D1 CACNB2 PKP2	1.37e-05	11	131	3	C1399226
Disease	CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)	CACNA2D1 CACNB2 PKP2	1.37e-05	11	131	3	C2748542
Disease	cranial vault morphology measurement	KIF6 LAMA4 ADAMTSL3 HACE1 RAB7A EMC2	1.73e-05	121	131	6	EFO_0009278
Disease	Sinus Node Dysfunction (disorder)	CACNA2D1 CACNB2 PKP2	3.74e-05	15	131	3	C0428908
Disease	hepatocyte growth factor measurement	CACNA2D1 MSANTD1 SERPINE2 BRWD1	4.39e-05	44	131	4	EFO_0006903
Disease	Arrhythmogenic Right Ventricular Dysplasia	SCN5A PKP2	5.85e-05	3	131	2	C0349788
Disease	carnosine measurement	GRIK2 HCRTR1 ZNF681	1.62e-04	24	131	3	EFO_0010470
Disease	response to 5-fluorouracil, response to antineoplastic agent	MYO1B SERPINE2	4.05e-04	7	131	2	GO_0036275, GO_0097327
Disease	Brugada syndrome	CACNB2 SCN5A	5.38e-04	8	131	2	cv:C1142166
Disease	Spastic Paraplegia	LYST HACE1	6.90e-04	9	131	2	C0037772
Disease	supraventricular ectopy	KIF6 SCN5A	6.90e-04	9	131	2	EFO_0009277
Disease	nephritis (implicated_via_orthology)	ITGA4 PTK2B	8.60e-04	10	131	2	DOID:10952 (implicated_via_orthology)
Disease	metabolic rate measurement	CACNB2 ANKS1A	1.05e-03	11	131	2	EFO_0005115
Disease	Shortened QT interval	CACNA2D1 CACNB2	1.05e-03	11	131	2	C0151879
Disease	Cardiomyopathy	LAMA4 SCN5A PKP2	1.20e-03	47	131	3	cv:C0878544
Disease	Oligospermia	TPCN1 BRWD1	1.25e-03	12	131	2	C0028960
Disease	triglyceride measurement, intermediate density lipoprotein measurement	A1CF CAPN3 CRTAC1 BRWD1	1.54e-03	111	131	4	EFO_0004530, EFO_0008595
Disease	pancreatic cancer (is_implicated_in)	ATR WNT9A ITGA4 HS3ST2	1.59e-03	112	131	4	DOID:1793 (is_implicated_in)
Disease	lifestyle measurement, alcohol consumption measurement	KIF6 MYRIP GRIK2 PLOD2	1.75e-03	115	131	4	EFO_0007878, EFO_0010724
Disease	brain edema (biomarker_via_orthology)	SERPINE2 C5	1.98e-03	15	131	2	DOID:4724 (biomarker_via_orthology)
Disease	hypertension (is_implicated_in)	EPHX2 CACNB2 KIF6 PTK2B	2.11e-03	121	131	4	DOID:10763 (is_implicated_in)
Disease	hypertension, white matter hyperintensity measurement	NBEAL1 PTGDR ZNF107	2.67e-03	62	131	3	EFO_0000537, EFO_0005665
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	NBEAL1 MORF4L1 ANKS1A	2.80e-03	63	131	3	EFO_0001645, EFO_0004792
Disease	lysophosphatidylcholine 22:6 measurement	CACNA2D1 SIPA1L2	2.86e-03	18	131	2	EFO_0010365
Disease	facial height measurement	CACNA2D1 SCN5A ANKS1A BRWD1	3.76e-03	142	131	4	EFO_0007856
Disease	tissue plasminogen activator measurement, coronary artery disease	NBEAL1 MORF4L1 ANKS1A	3.92e-03	71	131	3	EFO_0001645, EFO_0004791
Disease	hypertrophic cardiomyopathy (is_implicated_in)	CACNB2 LZTR1	4.26e-03	22	131	2	DOID:11984 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLYQRFKKTFRQYGK	FAM210A	121	Q96ND0
RGYAFVTFSNKVEAK	A1CF	96	Q9NQ94
TKNKKGYTFVAEAFT	ADGB	1056	Q8N7X0
NGEKEQKFYTFLKNS	GPX3	141	P22352
TKGKRFTYKFNFNKL	ETV3	106	P41162
NKVRNYRIFEKDSKF	SH3BP2	506	P78314
KVANYTSTGRFKKRF	ADGRE4P	286	Q86SQ3
FKEQSFVYKKDGNFL	B3GALT5	31	Q9Y2C3
TYKGVKFIDASNKNV	ANKS1A	986	Q92625
LYQGIKFEASQKKSA	CCKAR	236	P32238
QYKIQDKSVSFFAKG	ELP6	246	Q0PNE2
YQNDKLFQSKTFTAK	ADGRG7	326	Q96K78
KKGFHLRYTSTKFQD	BMP1	966	P13497
HEQRAKQGKFYSSKS	CACNB2	186	Q08289
SNYFLNFKKEVRNKI	NBEAL1	1961	Q6ZS30
YYGAFKDVKEKNRTS	PTGDR	286	Q13258
KKFSNQYKATIGADF	RAB7A	31	P51149
KGRQSFQYFLKKEFS	RGS9	311	O75916
DKSIKKGNNAFRVYR	IRF2	96	P14316
LGYVQASKRDKKFFA	NUDCD1	486	Q96RS6
YANYKKSRGNTDNKE	MORF4L1	236	Q9UBU8
FFDELKQTKRNAKVY	MSANTD1	61	Q6ZTZ1
KAKEFTNVYIKNFGE	PABPC4	186	Q13310
GFAFVQYDKEKNARA	HNRNPCL1	51	O60812
RFITDKHFYFNKTKG	HS3ST2	296	Q9Y278
NFYRSFQKRISKEKG	MADD	96	Q8WXG6
LKNKNDLFEYKFATG	LZTR1	146	Q8N653
GFAFVQYDKEKNARA	HNRNPCL2	51	B2RXH8
YSSFKTNQEKEFNKL	KIF15	821	Q9NS87
KLRGKAFYFVNGKVF	LIMD1	506	Q9UGP4
VQYTGRDSFKAFAKA	MGAT1	386	P26572
DNEYKKDFAKSRSQF	NRAP	1586	Q86VF7
IYGFLNTNFKKEIKA	NPY4R	321	P50391
LFGNKGNSKQYEIFK	PNLIP	376	P16233
KISKKGQFRSASAFF	MYO15A	46	Q9UKN7
GFAFVQYDKEKNARA	HNRNPCL3	51	B7ZW38
GNINLTFFTTKKKYD	LIPT1	111	Q9Y234
FQKKKNSVTYSFRQS	IQSEC1	791	Q6DN90
FLAQRGYFKDKAFVN	MED31	36	Q9Y3C7
LFKCGFFKRKYQQLN	ITGAE	1146	P38570
SNSKFDVNYAFGRVK	HACE1	51	Q8IYU2
DGFVNNKRESYKFKF	KIF6	46	Q6ZMV9
NKRESYKFKFQRIFD	KIF6	51	Q6ZMV9
FAFLQTGNYKEAKKI	LRPPRC	896	P42704
NTKKRTFVAADGKSY	SERPINE2	201	P07093
GFAFVQYDKEKNARA	HNRNPCL4	51	P0DMR1
AQRKGYFSKETSFQK	JAM2	261	P57087
LKFENGKARAKNTFY	PLOD2	231	O00469
EKNPNSSNYKKVDFF	HFM1	1386	A2PYH4
IIYNFLSGKFREQFK	HCRTR1	356	O43613
YFSKGTLKIANKQFT	RPA1	256	P27694
AAKSVKLQSFFSQYK	ATR	916	Q13535
LFKNYTIFEKKFGDR	CRNKL1	451	Q9BZJ0
RIAKFAFDYATKKGR	IDH3B	196	O43837
KKGFNSVATARIFYK	EPHX1	196	P07099
KFLETFGKQETNKRY	IFT80	721	Q9P2H3
EIQFYVQQFKKSGFR	EPHX2	446	P34913
SKKGKRNFFKAQLYT	BLM	186	P54132
KLGRFFFSGYDKKQT	CA4	66	P22748
KSFKFRNQQKIASQY	CCDC63	46	Q8NA47
YFTSNQKGKTATKDR	GABRG1	356	Q8N1C3
YNKDKKVRVFTFSVG	CACNA2D1	376	P54289
KNSRYAQYKNFKVGD	FGL1	181	Q08830
CFKQFKTNYEKRSFK	SLC1A3	186	P43003
KNFKNFEITIKARYF	C5	241	P01031
KAKSNKELYGFLFND	ITSN1	1471	Q15811
FAQYKLETKFKSGLN	CENPN	266	Q96H22
RKYNTFHKNASFFKK	BRWD1	1801	Q9NSI6
DAYFARASKEQKDKF	LYST	2356	Q99698
QKAATVYKTKGFAQR	MYBPHL	241	A2RUH7
VYKTKGFAQRDFSEA	MYBPHL	246	A2RUH7
KAFLDKQNQVKFGSY	ITGA4	236	P13612
KAGFFKRQYKSILQE	ITGA4	1001	P13612
GVATYTDKLFKFRNN	CRTAC1	141	Q9NQ79
RAYQFAGRSKKETKY	EMC2	266	Q15006
YSNSFNPGKNFKLVK	PTK2B	46	Q14289
FVAVGEFLYKSKKNA	GRIK2	836	Q13002
KGKRFTYKFNFSKLI	ETV3L	111	Q6ZN32
QKDFFLYNASKARSK	CAPN3	521	P20807
GSESFKFVEQQSYKR	SCAF11	1111	Q99590
YELIKKNKFQGFSVQ	DYRK3	296	O43781
FYLDVKQNAKGRFLK	PURB	46	Q96QR8
RFKKYKQAGSHSNSF	PTPRA	176	P18433
GKIEQTQASEKKFYF	LAMA4	1341	Q16363
NARKIKKFFTGYLDT	RSPH6A	451	Q9H0K4
FQKAFKYIVSGKIFS	TAAR3P	316	Q9P1P4
QSKLYRSEDYGKNFK	SORT1	141	Q99523
ESADKFYGVKFRNKV	SMC3	1181	Q9UQE7
YSKLSFQGTFTKFRK	TATDN2	506	Q93075
TKRDFNQFIKANEKY	SMARCA1	861	P28370
KFNVDAFKRFNKYIN	TRPC4AP	591	Q8TEL6
AFKRFNKYINTDAKF	TRPC4AP	596	Q8TEL6
AIESLGFKRFKYSKF	BMT2	296	Q1RMZ1
NLEKQTSKGKYFVTF	LARS1	36	Q9P2J5
LKTGFFEFQAAKDKY	LARS1	821	Q9P2J5
FYSTQKTFIVLNKGK	SCN5A	86	Q14524
FFFTKLKTAGYQAVK	SENP1	496	Q9P0U3
AKEKEGSQFNYRVAF	SIPA1L2	521	Q9P2F8
VFKNGKVTKSYSFDE	NAMPT	461	P43490
YKSFKNAIQDKLSFQ	SP140L	141	Q9H930
QKDKRFTSGKYQDVY	TRIOBP	2311	Q9H2D6
QKKANDKGFYSSQAI	SMCR8	216	Q8TEV9
EFGKTLENNSYKFLK	TET1	781	Q8NFU7
QNAKSGRYSVNFKKA	TRDV1	76	A0A1B0GX56
GRYSVNFKKAAKSVA	TRDV1	81	A0A1B0GX56
KGYSKKDFSSVFQFL	HIBADH	316	P31937
KTKANNRVADEAFYK	CLTA	156	P09496
QAKRYAEKRKFGFVD	PRPF8	41	Q6P2Q9
VFYGTEKDKNSVNFK	XRCC6	86	P12956
FQCNKYVKVFDKFSN	ZNF107	76	Q9UII5
YVKVFDKFSNSNRYK	ZNF107	81	Q9UII5
GKAYRFLSQFKQHIK	ZBTB21	676	Q9ULJ3
FQKDISQGLKFKEAY	ZNF3	116	P17036
YARTDGKVFQFLNAK	RPL24	21	P83731
SEYGKAAVAFKNAKQ	NAPG	36	Q99747
KYCFLKFKSFGSAQQ	REXO5	641	Q96IC2
EFARKQVTGFKKEYQ	SNX18	451	Q96RF0
DAFYKAKNEFAAKAT	VPS16	656	Q9H269
DQNSSAFKFYRKKVF	SUGP2	821	Q8IX01
IYGFLNTNFKKEIKA	NPY4R2	321	P0DQD5
LFSFFRDTDAKYKNK	PHF3	966	Q92576
QFLQSKNEGDKYKFF	SMC6	196	Q96SB8
KYVKVFGKFSNSNRD	ZNF479	161	Q96JC4
FKGINILVKSKAFQY	TPCN1	431	Q9ULQ1
YLKKFVKIARNNFQS	TTC29	336	Q8NA56
NLKYSSKFVKEFLGR	WNT9A	171	O14904
AKVFKNYLKVFFQRA	XPOT	946	O43592
FDFQRKQYGKLKKFT	ZGRF1	1436	Q86YA3
KYKEFGKSFCIFSNL	ZNF681	171	Q96N22
NTTVNFTYQFLKKKF	WASHC4	836	Q2M389
LKKREYGSKYTQNNF	SLC30A9	116	Q6PML9
SFAQVYQGQKKSKEA	TTC23	191	Q5W5X9
NKFGENKYDKSTFII	ZNF782	246	Q6ZMW2
KRFQSKSFPSYKEFS	VRTN	661	Q9H8Y1
TFDYKAVKQEGRFTK	TEX35	31	Q5T0J7
AYKKAQFKKTDFVNS	PKP2	856	Q99959
KSFKCIEYGKTFNQS	ZNF506	171	Q5JVG8
KGFYSAKSFQRHEKT	ZNF439	361	Q8NDP4
KNKQFEAAVKQGAYS	ADAMTSL3	1076	P82987
KTKEGKYRVDFHNFS	KCNJ1	331	P48048
FRANAGKKIYEFTLQ	MYO1B	861	O43795
YQFGKTKIFFRAGQV	MYO5A	741	Q9Y4I1
YQFGKTKIFFRAGQV	MYO5C	731	Q9NQX4
FYNNVKSRFKRFGSA	MYRIP	121	Q8NFW9