Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionproteoglycan binding

CFHR4 SLIT1 LRP1 CTSK CTSL CTSV

2.03e-07511006GO:0043394
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1B STAB1 LRP1

1.03e-06161004GO:0005041
GeneOntologyMolecularFunctiondemethylase activity

CYP1A2 KDM3A KDM3B KDM6A UTY

2.65e-06441005GO:0032451
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1B STAB1 LRP1

3.32e-06211004GO:0030228
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

USP6 CTSK CTSL CTSV CTSW USP33

4.61e-06861006GO:0004197
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM3A KDM3B KDM6A UTY

1.11e-05281004GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM3A KDM3B KDM6A UTY

1.68e-05311004GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM3A KDM3B KDM6A UTY

1.91e-05321004GO:0140457
GeneOntologyMolecularFunctionserpin family protein binding

CTSL CTSV

2.48e-0521002GO:0097655
GeneOntologyMolecularFunctionmiRNA binding

RBM10 AGO1 AGO4 ZC3H7B

9.73e-05481004GO:0035198
GeneOntologyMolecularFunctioncysteine-type carboxypeptidase activity

CTSL CTSV

1.48e-0441002GO:0016807
GeneOntologyMolecularFunctionhistone modifying activity

KDM3A KDM3B PRDM8 KMT5B PRDM16 KDM6A UTY

1.54e-042291007GO:0140993
GeneOntologyMolecularFunctionsulfur compound binding

OGDH METTL14 CFHR4 CFHR3 KMT5B SLIT1 LRP1 LTF

2.20e-043231008GO:1901681
GeneOntologyMolecularFunctionkininogen binding

CTSL CTSV

2.46e-0451002GO:0030984
GeneOntologyMolecularFunctionhistone H3K27me2/H3K27me3 demethylase activity

KDM6A UTY

2.46e-0451002GO:0071558
GeneOntologyMolecularFunctionhistone H3K9me/H3K9me2 demethylase activity

KDM3A KDM3B

2.46e-0451002GO:0140683
GeneOntologyMolecularFunctionregulatory RNA binding

RBM10 AGO1 AGO4 ZC3H7B

2.64e-04621004GO:0061980
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM3A KDM3B KDM6A UTY

3.17e-04651004GO:0016706
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

CFHR4 SLIT1 LRP1

4.05e-04291003GO:0043395
GeneOntologyMolecularFunctioncysteine-type endopeptidase activator activity involved in apoptotic process

CTSK CTSL CTSV

4.05e-04291003GO:0008656
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP6 CTSK CTSL CTSV CTSW USP33

4.12e-041921006GO:0008234
GeneOntologyMolecularFunctionpeptidase activator activity involved in apoptotic process

CTSK CTSL CTSV

5.44e-04321003GO:0016505
GeneOntologyMolecularFunctioncomplement binding

CFHR4 CFHR3 C3AR1

5.44e-04321003GO:0001848
GeneOntologyMolecularFunctioncollagen binding

MRC2 CTSK CTSL CTSV

7.33e-04811004GO:0005518
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

PDHA1 OGDH

8.74e-0491002GO:0016624
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR LRP1B STAB1 LRP1

8.79e-04851004GO:0038024
GeneOntologyMolecularFunctionfibronectin binding

CTSK CTSL CTSV

9.05e-04381003GO:0001968
GeneOntologyMolecularFunctioncysteine-type exopeptidase activity

CTSL CTSV

1.09e-03101002GO:0070004
GeneOntologyMolecularFunctiondioxygenase activity

KDM3A KDM3B KDM6A UTY

1.49e-03981004GO:0051213
GeneOntologyMolecularFunctioncomplement component C3b binding

CFHR4 CFHR3

1.59e-03121002GO:0001851
GeneOntologyMolecularFunctionlipopolysaccharide binding

ADGRB1 PTAFR LTF

1.79e-03481003GO:0001530
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

PRDM8 PRDM16

1.87e-03131002GO:0046974
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM3A KDM3B

2.17e-03141002GO:0032454
GeneOntologyMolecularFunctionimmunoglobulin receptor activity

FCER2 PIGR

2.17e-03141002GO:0019763
GeneOntologyMolecularFunctioncysteine-type endopeptidase regulator activity involved in apoptotic process

CTSK CTSL CTSV

2.51e-03541003GO:0043028
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP1A2 KDM3A KDM3B KDM6A UTY

2.94e-031941005GO:0016705
GeneOntologyMolecularFunctionmethyltransferase activity

TYW3 METTL14 PRDM8 KMT5B PRDM16

4.37e-032131005GO:0008168
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP1

4.45e-03201002GO:0034185
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

PRDM8 KMT5B PRDM16

4.83e-03681003GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

PRDM8 KMT5B PRDM16

5.03e-03691003GO:0016278
GeneOntologyMolecularFunctionpeptidase activator activity

CTSK CTSL CTSV

5.23e-03701003GO:0016504
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

TYW3 METTL14 PRDM8 KMT5B PRDM16

5.40e-032241005GO:0016741
GeneOntologyMolecularFunctionhistone methyltransferase activity

PRDM8 KMT5B PRDM16

5.44e-03711003GO:0042054
GeneOntologyMolecularFunctionS-adenosyl-L-methionine binding

METTL14 KMT5B

5.87e-03231002GO:1904047
GeneOntologyMolecularFunctionendopeptidase activity

USP6 LTF CTSK CTSL CTSV CTSW USP33

5.88e-034301007GO:0004175
GeneOntologyMolecularFunctionopsonin binding

CFHR4 CFHR3

6.91e-03251002GO:0001846
GeneOntologyBiologicalProcessendocytosis

VLDLR ADGRB1 LRP1B STAB1 USP6 FCER2 MRC2 MIB1 MKLN1 LRP1 C4BPA VAV3 LY75 CTSL USP33

1.32e-0582710215GO:0006897
GeneOntologyBiologicalProcesspositive regulation of transcytosis

PTAFR LRP1

2.42e-0521022GO:1904300
GeneOntologyBiologicalProcessregulation of transcytosis

PTAFR LRP1

2.42e-0521022GO:1904298
GeneOntologyCellularComponentvacuole

VLDLR TTC3 PGAP6 USP6 STS PIGR MTOR LRP1 C3AR1 C4BPA CTSK CTSL CTSV CTSW

1.71e-0491310414GO:0005773
GeneOntologyCellularComponentendolysosome lumen

CTSK CTSL

2.43e-0451042GO:0036021
GeneOntologyCellularComponentelongator holoenzyme complex

ELP1 ELP2

3.63e-0461042GO:0033588
GeneOntologyCellularComponentcell surface

VLDLR TNFRSF4 CFHR4 FCER2 MSLNL MRC2 LRP1 ROS1 LTF SLITRK6 LY75 CTSK CTSL CTSV KLRB1

3.89e-04111110415GO:0009986
GeneOntologyCellularComponentlysosome

VLDLR PGAP6 USP6 STS PIGR MTOR LRP1 C3AR1 CTSK CTSL CTSV CTSW

7.03e-0481110412GO:0005764
GeneOntologyCellularComponentlytic vacuole

VLDLR PGAP6 USP6 STS PIGR MTOR LRP1 C3AR1 CTSK CTSL CTSV CTSW

7.03e-0481110412GO:0000323
GeneOntologyCellularComponentRISC-loading complex

AGO1 AGO4

1.07e-03101042GO:0070578
GeneOntologyCellularComponentexternal side of plasma membrane

TNFRSF4 CFHR4 FCER2 LRP1 LY75 CTSK CTSL CTSV KLRB1

1.14e-035191049GO:0009897
GeneOntologyCellularComponentMLL3/4 complex

KDM6A UTY

1.57e-03121042GO:0044666
MousePhenoexcessive scratching

ELP1 PRDM8 CTSL CTSV

1.90e-0615884MP:0001412
MousePhenoperiodontal ligament necrosis

CTSL CTSV

3.92e-052882MP:0030515
MousePhenoabnormal lymph node medullary sinus morphology

CTSL CTSV

3.92e-052882MP:0011222
MousePhenodilated lymph node medullary sinus

CTSL CTSV

3.92e-052882MP:0011223
MousePhenoamyloidosis

CFHR4 CTSK CTSL CTSV

6.61e-0535884MP:0000604
MousePhenoabnormal amyloid deposition

CFHR4 CTSK CTSL CTSV

6.61e-0535884MP:0021152
DomainEGF

VLDLR ZAN LRP1B STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

1.89e-0912610310PF00008
DomainEGF

VLDLR FRAS1 ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

6.63e-0923510312SM00181
DomainEGF-like_dom

VLDLR FRAS1 ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

1.27e-0824910312IPR000742
DomainGrowth_fac_rcpt_

VLDLR FRAS1 LRP1B STAB1 EYS FAT1 IGFBP2 JAG1 SLIT1 LRP1

1.50e-0815610310IPR009030
DomainInhibitor_I29

CTSK CTSL CTSV CTSW

3.01e-0871034PF08246
DomainProt_inhib_I29

CTSK CTSL CTSV CTSW

3.01e-0871034IPR013201
DomainInhibitor_I29

CTSK CTSL CTSV CTSW

3.01e-0871034SM00848
DomainEGF_3

VLDLR ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

7.14e-0823510311PS50026
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR LRP1B EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

1.25e-071061038IPR000152
DomainEGF_1

VLDLR ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

1.63e-0725510311PS00022
DomainPept_asp_AS

CTSK CTSL CTSV CTSW

1.79e-07101034IPR025661
DomainEGF-like_CS

VLDLR ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

2.06e-0726110311IPR013032
DomainEGF_2

VLDLR ZAN LRP1B PGAP6 STAB1 EYS FAT1 NRXN3 JAG1 SLIT1 LRP1

2.40e-0726510311PS01186
DomainPept_his_AS

CTSK CTSL CTSV CTSW

2.79e-07111034IPR025660
DomainEGF_CA

VLDLR LRP1B STAB1 EYS FAT1 JAG1 SLIT1 LRP1

3.72e-071221038SM00179
DomainEGF-like_Ca-bd_dom

VLDLR LRP1B STAB1 EYS FAT1 JAG1 SLIT1 LRP1

4.22e-071241038IPR001881
DomainPept_C1

CTSK CTSL CTSV CTSW

6.00e-07131034SM00645
DomainPeptidase_C1A_C

CTSK CTSL CTSV CTSW

6.00e-07131034IPR000668
DomainPeptidase_C1

CTSK CTSL CTSV CTSW

6.00e-07131034PF00112
DomainPeptidase_C1A

CTSK CTSL CTSV CTSW

6.00e-07131034IPR013128
DomainEGF_Ca-bd_CS

VLDLR LRP1B EYS FAT1 JAG1 SLIT1 LRP1

1.08e-06971037IPR018097
DomainLY

VLDLR LRP1B LRP1 ROS1

1.14e-06151034SM00135
DomainLDLR_classB_rpt

VLDLR LRP1B LRP1 ROS1

1.14e-06151034IPR000033
DomainEGF_CA

VLDLR LRP1B EYS FAT1 JAG1 SLIT1 LRP1

1.24e-06991037PS01187
DomainASX_HYDROXYL

VLDLR LRP1B EYS FAT1 NRXN3 JAG1 LRP1

1.33e-061001037PS00010
Domain-

VLDLR ELP1 LRP1B LRP1 ROS1

2.29e-063910352.120.10.30
Domain6-blade_b-propeller_TolB-like

VLDLR ELP1 LRP1B LRP1 ROS1

5.30e-06461035IPR011042
DomainJmjC

KDM3A KDM3B KDM6A UTY

8.51e-06241034PF02373
DomainTHIOL_PROTEASE_CYS

CTSK CTSL CTSV CTSW

1.19e-05261034PS00139
DomainTHIOL_PROTEASE_ASN

CTSK CTSL CTSV CTSW

1.39e-05271034PS00640
DomainTHIOL_PROTEASE_HIS

CTSK CTSL CTSV CTSW

1.39e-05271034PS00639
DomainPept_cys_AS

CTSK CTSL CTSV CTSW

1.61e-05281034IPR000169
DomainJMJC

KDM3A KDM3B KDM6A UTY

2.79e-05321034PS51184
DomainJmjC_dom

KDM3A KDM3B KDM6A UTY

2.79e-05321034IPR003347
DomainDUF5050

LRP1B LRP1

3.01e-0521032IPR032485
DomainDUF5050

LRP1B LRP1

3.01e-0521032PF16472
DomainJmjC

KDM3A KDM3B KDM6A UTY

3.16e-05331034SM00558
DomainLAM_G_DOMAIN

EYS FAT1 NRXN3 SLIT1

5.57e-05381034PS50025
DomainLdl_recept_b

VLDLR LRP1B LRP1

5.67e-05141033PF00058
DomainLDLRB

VLDLR LRP1B LRP1

5.67e-05141033PS51120
DomainLaminin_G_2

EYS FAT1 NRXN3 SLIT1

6.84e-05401034PF02210
DomainLamG

EYS FAT1 NRXN3 SLIT1

9.99e-05441034SM00282
DomainEGF_CA

VLDLR LRP1B FAT1 JAG1 LRP1

1.13e-04861035PF07645
DomainVWC_out

FRAS1 ZAN JAG1

1.48e-04191033SM00215
DomainArgonaute_N

AGO1 AGO4

1.79e-0441032IPR032474
DomainArgonaute_Mid_dom

AGO1 AGO4

1.79e-0441032IPR032473
DomainArgoL2

AGO1 AGO4

1.79e-0441032IPR032472
DomainArgoN

AGO1 AGO4

1.79e-0441032PF16486
DomainArgoMid

AGO1 AGO4

1.79e-0441032PF16487
DomainArgoL2

AGO1 AGO4

1.79e-0441032PF16488
DomainC-type_lectin-like/link

STAB1 FCER2 MRC2 LY75 KLRB1

2.19e-04991035IPR016186
DomainLaminin_G

EYS FAT1 NRXN3 SLIT1

2.94e-04581034IPR001791
DomainDUF1785

AGO1 AGO4

2.98e-0451032SM01163
DomainCTDL_fold

STAB1 FCER2 MRC2 LY75 KLRB1

3.15e-041071035IPR016187
DomainArgoL1

AGO1 AGO4

4.45e-0461032PF08699
DomainArgoL1

AGO1 AGO4

4.45e-0461032IPR014811
DomainE1_dh

PDHA1 OGDH

4.45e-0461032PF00676
DomainDH_E1

PDHA1 OGDH

4.45e-0461032IPR001017
DomainhEGF

EYS JAG1 SLIT1

4.83e-04281033PF12661
DomainLRRCT

CHAD SLIT1 SLITRK6

7.19e-04321033PF01463
DomainPIWI

AGO1 AGO4

8.25e-0481032PS50822
DomainPiwi

AGO1 AGO4

8.25e-0481032SM00950
DomainPiwi

AGO1 AGO4

8.25e-0481032IPR003165
DomainPiwi

AGO1 AGO4

8.25e-0481032PF02171
DomainC_TYPE_LECTIN_1

FCER2 MRC2 LY75 KLRB1

1.00e-03801034PS00615
Domain-

NRDE2 TTC3 MTOR ZC3H7B KDM6A UTY

1.01e-0320710361.25.40.10
DomainPAZ

AGO1 AGO4

1.06e-0391032PS50821
DomainPAZ

AGO1 AGO4

1.06e-0391032SM00949
DomainPAZ_dom

AGO1 AGO4

1.06e-0391032IPR003100
DomainPAZ

AGO1 AGO4

1.06e-0391032PF02170
DomainZF_RING_1

UBR1 TTC3 RNF157 MIB1 NFXL1 RNF180 OBI1

1.15e-032911037PS00518
DomainVWC

FRAS1 ZAN JAG1

1.19e-03381033SM00214
DomainLectin_C

FCER2 MRC2 LY75 KLRB1

1.20e-03841034PF00059
DomainCLECT

FCER2 MRC2 LY75 KLRB1

1.20e-03841034SM00034
DomainC_TYPE_LECTIN_2

FCER2 MRC2 LY75 KLRB1

1.25e-03851034PS50041
DomainC-type_lectin-like

FCER2 MRC2 LY75 KLRB1

1.31e-03861034IPR001304
DomainZF_RING_2

UBR1 TTC3 RNF157 MIB1 NFXL1 RNF180 OBI1

1.32e-032981037PS50089
DomainLDLR_class-A_CS

VLDLR LRP1B LRP1

1.39e-03401033IPR023415
DomainCys-rich_flank_reg_C

CHAD LRRC70 SLIT1 SLITRK6

1.55e-03901034IPR000483
DomainTPR_1

TTC3 ZC3H7B KDM6A UTY

1.55e-03901034PF00515
DomainTPR_1

TTC3 ZC3H7B KDM6A UTY

1.55e-03901034IPR001440
DomainLRRCT

CHAD LRRC70 SLIT1 SLITRK6

1.55e-03901034SM00082
DomainVWF_dom

FRAS1 ZAN JAG1

1.60e-03421033IPR001007
DomainC-type_lectin_CS

FCER2 MRC2 LY75

1.71e-03431033IPR018378
DomainTPR-like_helical_dom

NRDE2 TTC3 MTOR ZC3H7B KDM6A UTY

1.85e-032331036IPR011990
Domain-

EYS FAT1 NRXN3 SLIT1

1.89e-039510342.60.120.200
DomainLdl_recept_a

VLDLR LRP1B LRP1

1.95e-03451033PF00057
Domain-

STAB1 FCER2 MRC2 KLRB1

2.04e-039710343.10.100.10
DomainSET

PRDM8 KMT5B PRDM16

2.08e-03461033SM00317
Domain-

VLDLR LRP1B LRP1

2.08e-034610334.10.400.10
DomainLRRNT

CHAD LRRC70 LRRC52 SLIT1

2.12e-03981034IPR000372
DomainLRRNT

CHAD LRRC70 LRRC52 SLIT1

2.12e-03981034SM00013
DomainZnf_RING

UBR1 TTC3 RNF157 MIB1 NFXL1 RNF180 OBI1

2.19e-033261037IPR001841
DomainTHDP-binding

PDHA1 OGDH

2.26e-03131032IPR029061
Domain-

PDHA1 OGDH

2.26e-031310323.40.50.970
DomainLDLRA_1

VLDLR LRP1B LRP1

2.35e-03481033PS01209
DomainLDLRA_2

VLDLR LRP1B LRP1

2.50e-03491033PS50068
DomainLDrepeatLR_classA_rpt

VLDLR LRP1B LRP1

2.50e-03491033IPR002172
DomainLDLa

VLDLR LRP1B LRP1

2.50e-03491033SM00192
DomainLRR_8

CHAD LRRC70 LRRC52 SLIT1 SLITRK6

2.58e-031711035PF13855
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES

CTSK CTSL CTSV

9.30e-068793M27796
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM3A KDM3B KDM6A UTY

1.95e-0529794MM14934
PathwayREACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR

CTSK CTSL CTSV

4.65e-0513793MM14659
PathwayREACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR

CTSK CTSL CTSV

4.65e-0513793M593
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM3A KDM3B ELP1 KMT5B ELP2 PRDM16 KDM6A UTY

1.38e-04272798M29619
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM3A KDM3B KDM6A UTY

1.73e-0450794M27232
PathwayBIOCARTA_DICER_PATHWAY

AGO1 AGO4

3.07e-045792M22079
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM3A KDM3B KMT5B PRDM16 KDM6A UTY

4.41e-04175796MM14941
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO1 AGO4

4.58e-046792MM14818
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO4

4.58e-046792MM15083
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFHR4 CFHR3

4.58e-046792M47880
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO4

6.39e-047792M46421
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

FAT1 JAG1 CTSL CTSV

7.42e-0473794MM15906
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

PRDM8 AGO1 AGO4

7.47e-0432793M48012
PathwayREACTOME_SIGNALING_BY_NOTCH2

FCER2 JAG1 MIB1

8.19e-0433793M604
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO4

8.49e-048792MM15082
PathwayWP_THIAMINE_METABOLIC_PATHWAYS

PDHA1 OGDH

1.09e-039792M39774
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO4

1.09e-039792M27340
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG1 MIB1

1.09e-039792M47866
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

AGO1 AGO4

1.09e-039792M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

AGO1 AGO4

1.09e-039792M46436
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

KDM3A AGO1 AGO4

1.15e-0337793M29790
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

CTSK CTSL CTSV

1.24e-0338793MM14611
Pubmed

Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.

CTSK CTSL CTSV

2.83e-083107319028686
Pubmed

An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury.

CTSK CTSL CTSV

2.83e-083107317889653
Pubmed

Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis.

CTSK CTSL CTSV

2.83e-083107330931961
Pubmed

Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.

CTSK CTSL CTSV

2.83e-083107322126332
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1B SACS LRP1

8.28e-0814107415082773
Pubmed

Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis.

CTSK CTSL CTSV

1.13e-074107317068745
Pubmed

Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis.

CTSK CTSL CTSV

1.13e-074107321251246
Pubmed

Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone.

CTSK CTSL CTSV

1.13e-074107316939398
Pubmed

Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13.

FANCC CTSL CTSV

2.82e-075107311829493
Pubmed

Thyroid functions of mouse cathepsins B, K, and L.

CTSK CTSL CTSV

2.82e-075107312782676
Pubmed

Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen.

CTSK CTSL CTSV

2.82e-075107318163891
Pubmed

Multiple sites on SARS-CoV-2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V.

CTSK CTSL CTSV

2.82e-075107333786919
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM3A KDM3B KMT5B KDM6A UTY

4.29e-0749107534368113
Pubmed

Mouse cathepsin M, a placenta-specific lysosomal cysteine protease related to cathepsins L and P.

CTSK CTSL CTSV

5.62e-076107310760593
Pubmed

UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.

MTOR KDM6A UTY

9.82e-077107329551674
Pubmed

Lysosomal processing of progranulin.

CTSK CTSL CTSV

1.57e-068107328835281
Pubmed

Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.

CTSK CTSL CTSV

1.57e-068107322916010
Pubmed

Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.

CFHR4 CFHR3 C4BPA

2.35e-069107320059470
Pubmed

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.

STT3B CTSL CTSV

3.34e-0610107320541250
Pubmed

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.

CTSL CTSV

9.38e-062107219801522
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

9.38e-062107215963947
Pubmed

Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis.

CTSL CTSV

9.38e-062107236735789
Pubmed

Cathepsin L promotes Vascular Intimal Hyperplasia after Arterial Injury.

CTSL CTSV

9.38e-062107228332696
Pubmed

Impaired turnover of autophagolysosomes in cathepsin L deficiency.

CTSL CTSV

9.38e-062107220536383
Pubmed

Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice.

CTSL CTSV

9.38e-062107216636100
Pubmed

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

CTSL CTSV

9.38e-062107231010818
Pubmed

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.

AGO1 AGO4

9.38e-062107233233493
Pubmed

An H-YDb epitope is encoded by a novel mouse Y chromosome gene.

KDM6A UTY

9.38e-06210728944031
Pubmed

Diabetes-Induced Jagged1 Overexpression in Endothelial Cells Causes Retinal Capillary Regression in a Murine Model of Diabetes Mellitus: Insights Into Diabetic Retinopathy.

JAG1 MIB1

9.38e-062107227407072
Pubmed

Serum cathepsin levels in coronary artery ectasia.

CTSK CTSL

9.38e-062107220837372
Pubmed

A variant of pulmonary alveolar microlithiasis in nackt mice.

CTSL CTSV

9.38e-062107212014504
Pubmed

mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy.

MTOR CTSK

9.38e-062107237938323
Pubmed

Mice that express enzymatically inactive cathepsin L exhibit abnormal spermatogenesis.

CTSL CTSV

9.38e-062107212533435
Pubmed

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.

LRP1 LTF

9.38e-06210721464627
Pubmed

Cathepsin L was involved in vascular aging by mediating phenotypic transformation of vascular cells.

CTSL CTSV

9.38e-062107236206719
Pubmed

Sequence and expression of the cDNA for MEP (major excreted protein), a transformation-regulated secreted cathepsin.

CTSL CTSV

9.38e-06210723689328
Pubmed

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.

CTSL CTSV

9.38e-062107217671649
Pubmed

The alpha -chains of C4b-binding protein mediate complex formation with low density lipoprotein receptor-related protein.

LRP1 C4BPA

9.38e-062107211705989
Pubmed

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.

CTSL CTSV

9.38e-062107221972973
Pubmed

Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.

CTSL CTSV

9.38e-062107216705169
Pubmed

Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts.

CTSL CTSV

9.38e-06210722835398
Pubmed

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

CTSL CTSV

9.38e-062107216079282
Pubmed

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation.

CTSL CTSV

9.38e-062107218957203
Pubmed

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus.

CTSL CTSV

9.38e-06210729545226
Pubmed

Cathepsin L gene expression and promoter activation in rodent granulosa cells.

CTSL CTSV

9.38e-062107214563703
Pubmed

Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity.

CTSL CTSV

9.38e-062107220877570
Pubmed

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

CTSL CTSV

9.38e-062107219900452
Pubmed

Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.

DAPK1 MTOR

9.38e-062107227930338
Pubmed

Thymocyte expression of cathepsin L is essential for NKT cell development.

CTSL CTSV

9.38e-062107212368909
Pubmed

Cloning and characterization of a mouse cysteine proteinase.

CTSL CTSV

9.38e-06210723533924
Pubmed

Surface activation of pro-cathepsin L.

CTSL CTSV

9.38e-06210721482371
Pubmed

Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation.

CTSL CTSV

9.38e-062107212163394
Pubmed

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.

CTSL CTSV

9.38e-062107220347002
Pubmed

Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy.

CTSL CTSV

9.38e-062107215154914
Pubmed

Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway.

IGFBP2 MTOR

9.38e-062107217289850
Pubmed

Evolution of placentally expressed cathepsins.

CTSL CTSV

9.38e-062107212054558
Pubmed

Cathepsin L is involved in proliferation and invasion of breast cancer cells.

CTSL CTSV

9.38e-062107226639231
Pubmed

An alternate targeting pathway for procathepsin L in mouse fibroblasts.

CTSL CTSV

9.38e-062107211929604
Pubmed

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis.

CTSL CTSV

9.38e-062107220023699
Pubmed

Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.

MTOR ROS1

9.38e-062107231053160
Pubmed

Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model.

CTSK CTSL

9.38e-062107225558848
Pubmed

Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.

CTSL CTSV

9.38e-062107218469859
Pubmed

Streptococcus pneumoniae Interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor.

PTAFR PIGR

9.38e-062107224841255
Pubmed

Pro-atherogenic shear stress and HIV proteins synergistically upregulate cathepsin K in endothelial cells.

CTSK CTSV

9.38e-062107224719048
Pubmed

Cathepsin L plays an active role in involution of the mouse mammary gland.

CTSL CTSV

9.38e-062107212815617
Pubmed

Response to comment on "Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number".

CTSL CTSV

9.38e-062107216621972
Pubmed

Cathepsin L regulates pathogenicCD4 T cells in experimental autoimmune encephalomyelitis.

CTSL CTSV

9.38e-062107233540247
Pubmed

The protease cathepsin L regulates Th17 cell differentiation.

CTSL CTSV

9.38e-062107226343333
Pubmed

Increased nucleolar localization of SpiA3G in classically but not alternatively activated macrophages.

CTSL CTSV

9.38e-062107220338168
Pubmed

Cathepsin L coexists with Cytotoxic T-lymphocyte Antigen-2 alpha in distinct regions of the mouse brain.

CTSL CTSV

9.38e-062107227586811
Pubmed

Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.

CTSL CTSV

9.38e-062107223912553
Pubmed

Cathepsin L Helps to Defend Mice from Infection with Influenza A.

CTSL CTSV

9.38e-062107227716790
Pubmed

The radiation-induced nackt (nkt) allele is a loss-of-function mutation of the mouse cathepsin L gene.

CTSL CTSV

9.38e-062107216393949
Pubmed

Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.

CTSL CTSV

9.38e-062107220304958
Pubmed

Characterization and comparative mapping of the porcine CTSL gene indicates a novel synteny between HSA9q21-->q22 and SSC10q11-->q12.

CTSL CTSV

9.38e-062107211978977
Pubmed

Comparison of cathepsin L synthesized by normal and transformed cells at the gene, message, protein, and oligosaccharide levels.

CTSL CTSV

9.38e-06210722275556
Pubmed

The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene.

CTSL CTSV

9.38e-062107211398968
Pubmed

Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex.

PDHA1 OGDH

9.38e-062107228242228
Pubmed

Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.

KDM6A UTY

9.38e-062107218434530
Pubmed

Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis.

CTSL CTSV

9.38e-062107223600672
Pubmed

Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice.

CTSL CTSV

9.38e-062107212466121
Pubmed

Clearance of Neutrophils From ICH-Affected Brain by Macrophages Is Beneficial and Is Assisted by Lactoferrin and CD91.

LRP1 LTF

9.38e-062107238063014
Pubmed

Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly.

CTSL CTSV

9.38e-062107210516062
Pubmed

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling.

CTSL CTSV

9.38e-062107219096818
Pubmed

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling.

CTSL CTSV

9.38e-062107211023992
Pubmed

Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins.

CTSL CTSV

9.38e-06210723755373
Pubmed

[Effect of bushen tiaojing recipe and xiaoyao pill on expression of cathepsin-L mRNA in gonadotropin-primed mice].

CTSL CTSV

9.38e-062107221434350
Pubmed

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.

KDM6A UTY

9.38e-062107227533081
Pubmed

Cell type-specific functions of the lysosomal protease cathepsin L in the heart.

CTSL CTSV

9.38e-062107217942402
Pubmed

The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.

CTSL CTSV

9.38e-062107215679121
Pubmed

Identification on melanoma cells of p39, a cysteine proteinase that cleaves C3, the third component of complement: amino-acid-sequence identities with procathepsin L.

CTSL CTSV

9.38e-06210728554545
Pubmed

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.

CTSL CTSV

9.38e-062107219589362
Pubmed

Cathepsin L is essential for onset of autoimmune diabetes in NOD mice.

CTSL CTSV

9.38e-062107216184198
Pubmed

Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice.

CTSL CTSV

9.38e-062107221868704
Pubmed

Cathepsin-L contributes to cardiac repair and remodelling post-infarction.

CTSL CTSV

9.38e-062107221147810
Pubmed

Identification of a membrane-associated cysteine protease with possible dual roles in the endoplasmic reticulum and protein storage vacuole.

CTSL CTSV

9.38e-062107211022031
Pubmed

B-cell lymphopoiesis is regulated by cathepsin L.

CTSL CTSV

9.38e-062107223585893
Pubmed

Positive and negative selection on mammalian Y chromosomes.

KDM6A UTY

9.38e-062107215758204
Pubmed

Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.

KDM6A UTY

9.38e-062107231097364
Pubmed

Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

CTSL CTSV

9.38e-062107227575559
Cytoband1q32

CFHR4 CFHR3 C4BPA

2.10e-044910731q32
GeneFamilyCathepsins

CTSK CTSL CTSV CTSW

3.23e-0715734470
GeneFamilyPHD finger proteins|Lysine demethylases

KDM3A KDM3B KDM6A UTY

2.44e-0624734485
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1B LRP1

1.75e-0513733634
GeneFamilyC-type lectin domain family

FCER2 MRC2 LY75 KLRB1

3.83e-0547734494
GeneFamilyElongator acetyltransferase complex

ELP1 ELP2

2.39e-046732539
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

PRDM8 KMT5B PRDM16

3.45e-0434733487
GeneFamilyZinc fingers CCCH-type

ZC3H11B ZC3H11A ZC3H7B

3.77e-043573373
GeneFamilyComplement system|Sushi domain containing

CFHR4 CFHR3 C3AR1

4.10e-0436733492
GeneFamilyArgonaute/PIWI family

AGO1 AGO4

4.43e-048732408
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TNFRSF4 FCER2 MRC2 JAG1 LRP1 LY75 KLRB1

1.05e-03394737471
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

APOBEC3B LY75 UTY

1.14e-0351733870
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC3 ZC3H7B KDM6A UTY

1.21e-03115734769
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFHR4 CFHR3 C4BPA

1.58e-03577331179
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM8 PRDM16

2.10e-03177321197
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB1 LY75

5.29e-03277321253
CoexpressionROSS_AML_WITH_PML_RARA_FUSION

TNFRSF4 STAB1 IGFBP2 MRC2 JAG1 CTSW

9.45e-07801076M15368
CoexpressionGSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP

TYW3 EMB CFHR4 STAB1 FCER2 SPHKAP NFXL1

1.80e-051991077M6131
CoexpressionGSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP

PTAFR TNFRSF4 STAB1 FCER2 C3AR1 CTSV UTY

1.86e-052001077M5100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-2fold-vs-F_top305_305

ZNF560 TTC3 RNF157 JAG1 MYOM2 SLITRK6 CTSK UTY

3.76e-052661008gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F-2X
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3

PTAFR LRP1 C3AR1 CTSK CTSL

4.04e-05811005GSM605865_100
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN LRP1B TNFRSF4 NRXN3 IGFBP2 LTF

1.77e-07169107712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

SGMS2 EMB PTAFR GASK1B TMEM91 STAB1 LRP1

4.50e-0719410779e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCellmLN-(4)_Monocyte|mLN / shred on region, Cell_type, and subtype

SGMS2 DAPK1 GASK1B STAB1 MTMR11 LRP1 C3AR1

5.35e-0719910776795ff31f92580195c9db776951f99d647484d24
ToppCellmLN-Monocyte|mLN / Region, Cell class and subclass

SGMS2 DAPK1 GASK1B STAB1 MTMR11 LRP1 C3AR1

5.35e-071991077241f790cd5d8a9b2451333deecc826a673bae70a
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SGMS2 PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

5.35e-0719910770f3ce61bbae69f7e333ed8dacf7257645624e163
ToppCellmLN-Monocyte-Monocyte|mLN / Region, Cell class and subclass

SGMS2 DAPK1 GASK1B STAB1 MTMR11 LRP1 C3AR1

5.35e-071991077dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCellmLN-(4)_Monocyte-(40)_Monocyte|mLN / shred on region, Cell_type, and subtype

SGMS2 DAPK1 GASK1B STAB1 MTMR11 LRP1 C3AR1

5.35e-071991077bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

DAPK1 PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

5.53e-072001077b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

DAPK1 PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

5.53e-0720010779e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 CHAD RAD51AP2 NRXN3 PIGR LTF

3.39e-061691076db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 CHAD RAD51AP2 NRXN3 PIGR LTF

3.39e-06169107697b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 CHAD RAD51AP2 NRXN3 PIGR LTF

3.39e-0616910761a684471dbda42e1470e5a889648666e14f25982
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DAPK1 APOBEC3B GASK1B STAB1 LRP1 C3AR1

3.51e-0617010769ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DIPK2A STAB1 FCER2 LRP1 NFXL1 C3AR1

3.63e-0617110765e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

SGMS2 DAPK1 GASK1B STAB1 LRP1 CTSL

4.01e-0617410760746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellCOPD-Lymphoid-ILC_A|COPD / Disease state, Lineage and Cell class

EMB JAG1 PLCL2 VAV3 KLRB1 CTSW

4.29e-061761076484452cb38fe4604f0910a068361ed461b5b0c21
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN LRP1B FAT1 ROS1 MYOM2

5.53e-0618410762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN LRP1B FAT1 ROS1 MYOM2

5.53e-061841076ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN LRP1B FAT1 ROS1 MYOM2

5.53e-0618410762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

IGFBP2 JAG1 PLCL2 VAV3 KLRB1 CTSW

5.71e-061851076520795866d44def5be3910ce8e728045c716a24d
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

5.71e-061851076755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1B GASK1B STAB1 LRP1 NFXL1 PRDM16

5.89e-06186107623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

6.45e-061891076b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

6.85e-0619110769b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

VLDLR SGMS2 FAT1 MRC2 SLITRK6 CTSK

7.06e-0619210760703b8ec6960ff975ee5a2737054db67cab016b5
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

7.27e-061931076f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

7.27e-0619310761cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VLDLR SGMS2 FAT1 MRC2 SLITRK6 CTSK

7.27e-061931076035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SGMS2 DAPK1 STAB1 LRP1 C3AR1 CTSL

7.27e-06193107600c9c2945d2bdaa128e054cf3c59df86a279b659
ToppCellMild-NK|Mild / Disease group and Cell class

TNFRSF4 JAG1 VAV3 MYOM2 KLRB1 CTSW

7.71e-061951076be88a7507cd6a0a9dfe424312d9365039eef7b74
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SGMS2 PTAFR GASK1B STAB1 LRP1 C3AR1

7.71e-061951076403d874198a7bde626b0d0b4efad8dbb34060761
ToppCellCOVID-19-lung-NK/NKT|lung / Disease (COVID-19 only), tissue and cell type

EMB PLCL2 VAV3 MYOM2 KLRB1 CTSW

7.71e-0619510763ab941a369e3815f338890b116dc77aefa054098
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DAPK1 GPR160 FAT1 VAV3 PRDM16

7.94e-061961076c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell(7)_Monocyte|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PTAFR GASK1B STAB1 MTMR11 LRP1 C3AR1

7.94e-0619610760232167559dcd2d86ee8b78017cf5f2a084b2cb7
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

EMB PTAFR GASK1B STAB1 ZC3H11A LRP1

7.94e-061961076f245e929a286cb097130572e1027b4f01be8b04d
ToppCell(6)_Macrophage|World / shred on Cell_type and subtype

DAPK1 PTAFR GASK1B STAB1 LRP1 CTSL

8.17e-061971076010b275d4da4a896175ad7fbaa96d1dc11a0b744
ToppCellNS-moderate-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.17e-061971076774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCell(7)_MNP|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.17e-0619710766790346736946984cc80d67668523ba70ab0b380
ToppCell10x5'-lymph-node_spleen-Myeloid_Monocytic|lymph-node_spleen / Manually curated celltypes from each tissue

PTAFR GASK1B STAB1 MTMR11 LRP1 C3AR1

8.41e-0619810762541f1095ed91e6789cb888cf39a208b8107726a
ToppCellVE-mono1-|VE / Condition, Cell_class and T cell subcluster

PTAFR APOBEC3B STAB1 LRP1 C3AR1 CTSL

8.41e-0619810762959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DAPK1 GASK1B STAB1 LRP1 C3AR1 CTSL

8.41e-061981076579a22199643440b98e381147779ced630d4ed66
ToppCellVE-mono1|VE / Condition, Cell_class and T cell subcluster

PTAFR APOBEC3B STAB1 LRP1 C3AR1 CTSL

8.41e-061981076c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.41e-06198107609009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCell10x5'-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

PTAFR GASK1B STAB1 MTMR11 LRP1 C3AR1

8.41e-061981076934dacb67d71faa2f8732c39d7f8e64b0ee75396
ToppCellMonocytes|World / Immune cells in Kidney/Urine in Lupus Nephritis

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.41e-0619810768beccf03c9ec9cd02a96107a9d7ca9a6764c6a61
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DAPK1 GASK1B STAB1 LRP1 C3AR1 CTSL

8.66e-061991076c4fc638a8dad3a9b77634e8912a9326c8a2f11f5
ToppCell10x5'-bone_marrow-Myeloid_Monocytic|bone_marrow / Manually curated celltypes from each tissue

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.66e-06199107662b0861faf173eead75678aad10d396cd0d80c2c
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

PTAFR GASK1B STAB1 MTMR11 AGO1 LRP1

8.66e-061991076ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DAPK1 GASK1B LRP1 C3AR1 CTSK CTSL

8.66e-06199107680ed217d28ba1c07facd0e103c25a02658dd848d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DAPK1 GASK1B STAB1 LRP1 C3AR1 CTSL

8.66e-061991076697a9a58c0cdb77222700d029873355d37f6ab28
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DAPK1 GASK1B STAB1 LRP1 C3AR1 CTSL

8.66e-0619910766783d571d28eac891fcc70380f176b53f35c88ba
ToppCellSigmoid-Macrophage-Macrophage|Sigmoid / Region, Cell class and subclass

DAPK1 PTAFR GASK1B STAB1 LRP1 CTSL

8.91e-0620010769ee3a799de7bade1bfe94b6827461633f02bc1dc
ToppCellSigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.91e-062001076bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
ToppCellSigmoid-(6)_Macrophage-(60)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

DAPK1 PTAFR GASK1B STAB1 LRP1 CTSL

8.91e-062001076ad84a83a5a1893f7b053d39eddeca851463a8ff0
ToppCellSigmoid-Macrophage-LYVE1_Macrophage|Sigmoid / Region, Cell class and subclass

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

8.91e-062001076851a1b372ddbec522829069e69ed36a1f4832131
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 EMB RNF157 NRXN3 IGFBP2 SLITRK6

8.91e-062001076de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PTAFR GASK1B STAB1 IGFBP2 LRP1 C3AR1

8.91e-062001076a3f22826f3d8f917ff0594bdadd93b60763bcaa2
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

PTAFR GASK1B STAB1 LRP1 C3AR1 CTSL

1.05e-052061076711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTAFR STAB1 C3AR1 VAV3 RNF180

2.40e-051421075bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

FAT1 STS ROS1 C4BPA LTF

3.12e-051501075b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

CHAD TNFRSF4 FAT1 NRXN3 KLRB1

3.42e-0515310754ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 FANCC TBC1D32 UTY TOP3A

3.99e-0515810751d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTAFR PGAP6 GPR160 STAB1 C3AR1

4.50e-051621075ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLYATL2 LRP1B PIGR LTF CTSV

4.63e-051631075be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF560 ZC3H11B PRAG1 IGFBP2 SMCR5

4.77e-051641075d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBR1 GASK1B MTMR11 JAG1 WDFY1

4.91e-05165107562457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellmild-Myeloid-CD14_Monocytes_3|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GASK1B STAB1 LRP1 C3AR1 CTSL

4.91e-051651075a6547bb2c9c40b4878325da19b9def0ef644fa25
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 PIGR NFXL1 LTF SLITRK6

5.05e-05166107560060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 PIGR NFXL1 LTF SLITRK6

5.05e-051661075ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

FRAS1 FAM217A JAG1 KLRB1 CTSW

5.05e-051661075ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 PIGR NFXL1 LTF SLITRK6

5.05e-0516610754586d6725403f879fc96f67be579022587ce1906
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

PTAFR GASK1B TMEM91 STAB1 LRP1

5.20e-0516710757d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTAFR PGAP6 GPR160 STAB1 C3AR1

5.81e-051711075bf475a69db04d4a886e442704955c6a96ff0de46
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DAPK1 TNFRSF4 STAB1 C3AR1 CTSW

5.98e-051721075c477008444d2d71071177807870d7455e90c2fad
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 ADGRB1 RNF157 NRXN3 SLITRK6

5.98e-051721075bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

JAG1 PLCL2 VAV3 KLRB1 CTSW

6.14e-0517310754a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

SGMS2 PTAFR GASK1B STAB1 LRP1

6.14e-051731075783b8fa08b9d8f597f251793eae164151662f1f9
ToppCellInt-URO-Lymphocyte-T_NK-NK_CD56bright|Int-URO / Disease, Lineage and Cell Type

TNFRSF4 TBC1D32 PRDM16 KLRB1 CTSW

6.31e-05174107593c7acd5941a5f235ec4c57461f78ee2871e7336
ToppCellCOPD-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

EMB PLCL2 VAV3 KLRB1 CTSW

6.49e-051751075e773e330de36f8a0aa9398a176ed7edb5599c582
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ZNF106 KMT5B VAV3 KDM6A

6.66e-051761075749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTAFR GPR160 STAB1 NFXL1 C3AR1

6.66e-051761075adb679e69c0c17f0caee4c141bac55d03c963012
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRAG1 PRDM8 SPHKAP ROS1 VAV3

6.66e-05176107540993c41c1017b53039a337174fc56632b278609
ToppCellControl-Lymphoid-ILC_B|World / Disease state, Lineage and Cell class

TNFRSF4 JAG1 PLCL2 KLRB1 CTSW

6.66e-05176107557ad9c9f5fda6bc24695587ed14190514fd8d96a
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTAFR GPR160 STAB1 NFXL1 C3AR1

6.84e-051771075ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRDM8 STS C3AR1 KLRB1 CTSW

6.84e-0517710759828504591599619649d41a78daf7c052729c669
ToppCellControl-Lymphoid-ILC_B|Control / Disease state, Lineage and Cell class

TNFRSF4 JAG1 PLCL2 KLRB1 CTSW

6.84e-0517710753d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

GLYATL2 CHAD PIGR C4BPA SLITRK6

7.03e-051781075f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 SGMS2 FAT1 MRC2 RNF180

7.03e-051781075e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 DAPK1 NRXN3 ROS1 PRDM16

7.22e-051791075815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAD51AP2 NRXN3 PIGR C4BPA PRDM16

7.22e-051791075fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellSomatosensory_Cortex_(S1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 PRAG1 ROS1 VAV3 UTY

7.22e-05179107582348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

GLYATL2 CHAD GASK1B PIGR C4BPA

7.41e-051801075a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCelllymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell|World / Lineage, cell class and subclass

TNFRSF4 MYOM2 PRDM16 KLRB1 CTSW

7.61e-0518110750d096d7d557fd2e71b35e41816e11d7e83cd9210
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CHAD TNFRSF4 EYS JAG1 KLRB1

7.81e-0518210756bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellIPF-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

EMB PLCL2 VAV3 KLRB1 CTSW

7.81e-051821075f91bb45baaec76cb3bb26eedbcf0709b2492e93f
DrugZ-Phe-Phe-CHN2

STS CTSL CTSV CTSW

4.39e-06241064CID005486921
DrugAb-Z

CYP1A2 CTSK CTSL CTSV TOP3A

6.29e-06561065CID000448533
Drugchloroquine

CYP1A2 EMB STS LRP1 C3AR1 CTSK CTSL CTSV CTSW

8.23e-062881069CID000002719
Drugcimaterol

CTSK CTSL CTSV CTSW

9.64e-06291064CID000002755
DrugE64A

CTSK CTSL CTSV CTSW

1.27e-05311064CID000173548
DrugC01631

CTSK CTSL CTSV CTSW

1.27e-05311064CID000439539
Drugdesmedipham

CTSK CTSL CTSV CTSW

1.27e-05311064CID000024743
DrugCompound-1

FANCC JAG1 CTSK CTSL CTSV CTSW

2.00e-051191066CID006324619
Drug3-Amino-5-Phenylpentane

CTSK CTSV

2.15e-0521062DB02869
DiseaseNeoplasm of uncertain or unknown behavior of bladder

FANCC MTOR KDM6A

1.82e-05151033C0496930
DiseaseBenign neoplasm of bladder

FANCC MTOR KDM6A

1.82e-05151033C0154017
DiseaseCarcinoma in situ of bladder

FANCC MTOR KDM6A

1.82e-05151033C0154091
DiseaseMalignant neoplasm of salivary gland

DAPK1 FAT1 IGFBP2 JAG1

1.87e-05451034C0220636
DiseaseSalivary Gland Neoplasms

DAPK1 FAT1 IGFBP2 JAG1

2.23e-05471034C0036095
Diseaseotitis media (biomarker_via_orthology)

CTSK CTSL CTSV

2.71e-05171033DOID:10754 (biomarker_via_orthology)
DiseaseAdenoid Cystic Carcinoma

DAPK1 FAT1 IGFBP2 JAG1 KDM6A

2.72e-051001035C0010606
DiseaseCarcinoma of bladder

FANCC MTOR KDM6A

3.24e-05181033C0699885
DiseaseKabuki syndrome (implicated_via_orthology)

KDM6A UTY

3.61e-0531032DOID:0060473 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

KDM3A KDM3B CTSL CTSV KDM6A UTY

6.48e-051951036DOID:1574 (implicated_via_orthology)
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFHR4 CFHR3

7.21e-0541032EFO_0803292
Diseasenephrotic syndrome (biomarker_via_orthology)

VLDLR CTSL CTSV

7.93e-05241033DOID:1184 (biomarker_via_orthology)
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

1.20e-0451032EFO_0004647, EFO_0006952
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 MTOR KDM6A

1.27e-04281033DOID:5409 (is_implicated_in)
DiseaseGlioblastoma

FAT1 MTOR JAG1 CTSK

1.72e-04791034C0017636
Diseaseobesity

ZC3H11B PRAG1 FAT1 NRXN3 PRDM16 KLRB1

2.06e-042411036EFO_0001073
DiseaseGiant Cell Glioblastoma

FAT1 MTOR JAG1 CTSK

2.18e-04841034C0334588
DiseaseAcute Confusional Migraine

LRP1 PRDM16

4.28e-0491032C0521664
DiseaseStatus Migrainosus

LRP1 PRDM16

4.28e-0491032C0338489
DiseaseAtypical hemolytic-uremic syndrome

CFHR4 CFHR3

4.28e-0491032cv:C2931788
DiseaseAbdominal Migraine

LRP1 PRDM16

4.28e-0491032C0270858
DiseaseHemolytic-uremic syndrome

CFHR4 CFHR3

4.28e-0491032cv:C0019061
DiseaseSick Headaches

LRP1 PRDM16

4.28e-0491032C0700438
DiseaseCervical Migraine Syndrome

LRP1 PRDM16

4.28e-0491032C0007852
DiseaseHemicrania migraine

LRP1 PRDM16

4.28e-0491032C0018984
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma

DAPK1 EYS PRDM16

4.30e-04421033EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
DiseaseMalignant Head and Neck Neoplasm

APOBEC3B FANCC FAT1

4.93e-04441033C0278996
DiseaseGlioblastoma Multiforme

FAT1 MTOR JAG1 CTSK

6.30e-041111034C1621958
DiseaseAshkenazi Jewish disorders

ELP1 FANCC

6.50e-04111032cv:CN118946
Diseasecolorectal cancer (is_implicated_in)

RBM10 LRP1B FAT1 KDM6A

8.70e-041211034DOID:9256 (is_implicated_in)
DiseaseMigraine Disorders

LRP1 PRDM16

9.18e-04131032C0149931
DiseaseAntithrombotic agent use measurement

TMEM91 FANCC PRDM8

9.50e-04551033EFO_0009925
DiseaseLeft ventricular noncompaction

MIB1 PRDM16

1.07e-03141032C1960469
DiseaseMalignant Neoplasms

APOBEC3B MTOR LTF KDM6A

1.07e-031281034C0006826
Disease1,3,7-trimethylurate measurement

CYP1A2 FRAS1

1.23e-03151032EFO_0021172
Diseaselung non-small cell carcinoma (is_implicated_in)

LRP1B FAT1 LTF KDM6A

1.45e-031391034DOID:3908 (is_implicated_in)
DiseaseBladder Neoplasm

APOBEC3B FANCC MTOR KDM6A

1.49e-031401034C0005695
DiseaseMalignant neoplasm of urinary bladder

APOBEC3B FANCC MTOR KDM6A

1.53e-031411034C0005684
DiseaseFamilial Progressive Myoclonic Epilepsy

PRDM8 SACS

1.59e-03171032C0751777
DiseaseAtypical Inclusion-Body Disease

PRDM8 SACS

1.59e-03171032C0751776
DiseaseMyoclonic Epilepsies, Progressive

PRDM8 SACS

1.59e-03171032C0751778
DiseaseBiotin-Responsive Encephalopathy

PRDM8 SACS

1.59e-03171032C0751780
DiseaseMay-White Syndrome

PRDM8 SACS

1.59e-03171032C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

PRDM8 SACS

1.59e-03171032C0751781
DiseaseBenign Neoplasm

APOBEC3B LTF KDM6A

1.76e-03681033C0086692
DiseaseNeoplasms

APOBEC3B LTF KDM6A

1.76e-03681033C0027651
Diseasebipolar disorder, sex interaction measurement

ADGRB1 SLIT1

1.78e-03181032EFO_0008343, MONDO_0004985
DiseaseAction Myoclonus-Renal Failure Syndrome

PRDM8 SACS

1.78e-03181032C0751779
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DAPK1 LRP1B MTOR KDM6A

1.83e-031481034C0279702
DiseaseAntimigraine preparation use measurement

LRP1 PRDM16

2.43e-03211032EFO_0009939
Diseasedilated cardiomyopathy (implicated_via_orthology)

JAG1 CTSL CTSV

2.79e-03801033DOID:12930 (implicated_via_orthology)
Diseasehematocrit

VLDLR ZAN PGAP6 STAB1 FANCC PRDM8 FAT1 JAG1 PLCL2 PRDM16

2.84e-03101110310EFO_0004348
Diseaseleptin measurement

LRP1B NRXN3 SLIT1

2.89e-03811033EFO_0005000
DiseaseCancer of Head

APOBEC3B FAT1

3.17e-03241032C0751177
DiseaseHead Neoplasms

APOBEC3B FAT1

3.17e-03241032C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

APOBEC3B FAT1

3.17e-03241032C0887900
DiseaseNeck Neoplasms

APOBEC3B FAT1

3.44e-03251032C0027533
Diseasecorpus collosum mid-posterior volume measurement

VLDLR JAG1

3.44e-03251032EFO_0010300
DiseaseCancer of Neck

APOBEC3B FAT1

3.44e-03251032C0746787

Protein segments in the cluster

PeptideGeneStartEntry
YVTPVKNQGQCGSCW

CTSK

126

P43235
VICQKNLRWTPYQGC

C4BPA

346

P04003
PCGIFHKVQVNLCRW

DAPK1

1141

P53355
CGNQLPAYKCFQITW

APOBEC3B

76

Q9UH17
FAPSQICLQWITQCF

TBC1D32

1151

Q96NH3
TRDCFLQQCPVDGKW

ADGRB1

511

O14514
VTPVKNQKQCGSCWA

CTSV

126

O60911
IKVWAIACFAPQKQC

AGO1

446

Q9UL18
PYQCLGARKLCQCQW

C17orf78

211

Q8N4C9
KVWAVACFAPQKQCR

AGO4

441

Q9HCK5
ALTNNPWKCTCQLRG

CHAD

296

O15335
CLVVFKPIWCQNHRN

C3AR1

121

Q16581
NRGNCWIINNCKTKC

RAD51AP2

406

Q09MP3
PKINEDWLCNKCGVQ

RBM10

211

P98175
IPKKCCVFVNQWQVN

CYP1A2

401

P05177
LNVFQKLCAGLDCPW

FAT1

3731

Q14517
DLCQDPTKLLQNGWC

FRAS1

436

Q86XX4
DQFRCSNGQCIPAKW

LRP1B

3556

Q9NZR2
PCKNNGSCINKRENW

EYS

221

Q5T1H1
WSCQLPCGQKLLCGQ

NFXL1

306

Q6ZNB6
ICTNFRVTFQPCGWQ

MTMR11

71

A4FU01
ASQFVCKNDKCIPFW

LRP1

3336

Q07954
CEDICWIKTNKNNPG

METTL14

256

Q9HCE5
TRKNCAQLWLGPAAF

KMT5B

256

Q4FZB7
NIAWNVGPLTACQYK

KDM6A

1236

O15550
GECWCVNPNTGKLIQ

IGFBP2

281

P18065
SGFVCNTCPEKWINF

FCER2

156

P06734
LKEPENCNNFCLWKQ

NRDE2

771

Q9H7Z3
PCKNNAVCKDGWNRF

NRXN3

651

Q9Y4C0
CIDLWLKNNSQCPAC

OBI1

41

Q5W0B1
GKWGIKANCPCISRQ

KDM3B

1116

Q7LBC6
LWLSLAKNCFAPQCP

LRRC71

516

Q8N4P6
CSEQWIPFQNKCFLK

LY75

951

O60449
GCPSDWIQFLNKCFQ

MRC2

971

Q9UBG0
LETLFLSGNPWKCNC

LRRC52

176

Q8N7C0
AFLTCGNWKQALCVA

ELP1

1021

O95163
CSLLQGFWCQPASQL

MSLNL

56

Q96KJ4
NFQKVLTCTGAPWPC

PGAP6

251

Q9HCN3
ANSNPWECNCKLLGL

LRRC70

356

Q7Z2Q7
QPIIGIRWKCAECTN

MIB1

91

Q86YT6
FVNWKCCFIPLTIPN

GPR160

311

Q9UJ42
CIIDQFICPGQAKWV

OGDH

756

Q02218
KPGQLINWFICSLCV

GASK1B

6

Q6UWH4
CIRFWNTLTGQPLQC

FZR1

381

Q9UM11
LWVSCANGQVKPCDF

CFHR3

11

Q02985
TCLQNGWSAQPICIN

CFHR3

191

Q02985
VRAKWGIKANCPCSN

KDM3A

741

Q9Y4C1
WERPCFQAHLGCLQN

LINC01555

71

Q8NAE3
QLNKCPACFGTSWCR

DIPK2A

51

Q8NDZ4
IWCLCCLINKEPQNS

FANCC

91

Q00597
ISPIKDQKNCNCCWA

CTSW

141

P56202
QNGWSTQPICIKFCD

CFHR4

136

Q92496
CLQNGWSAQPICIKF

CFHR4

381

Q92496
TVLTCKCQNCFPLNW

EMB

176

Q6PCB8
VNCIQWICKQDGSPS

ELP2

61

Q6IA86
KQGIFQLWNCPLNEG

FAM217A

81

Q8IXS0
FKQCDVLQLLWTSCP

SACS

3691

Q9NZJ4
QKAQWTVGKLNCPFC

RNF180

76

Q86T96
DLVNGFKCVCPPQWT

JAG1

391

P78504
GQLHQQCCEKWTLVN

MTOR

1491

P42345
CNNIAWNVGPLTACQ

UTY

1181

O14607
AICLDNSSGKQPWFC

SPHKAP

946

Q2M3C7
QNPTNCWICLPLNFR

ERVW-1

181

Q9UQF0
NKLCSEVCLPGAWQA

RNF157

631

Q96PX1
CSCDLVGLQQWIQKL

SLITRK6

521

Q9H5Y7
QWCAVSQPEATKCFQ

LTF

26

P02788
NNPWNKLCLVSMDFC

TMEM191A

11

Q9H0A3
SGLFAFNCQCQTWKL

MKLN1

426

Q9UL63
GNWILPKFLCNVAGC

PTAFR

81

P25105
CDQCPKAFNWKSNLI

PRDM16

311

Q9HAZ2
LPAQNWCAKCNASFR

PRDM8

621

Q9NQV8
NMNPQDFWKCGCQIV

PLCL2

686

Q9UPR0
NNFLWKPWLQLCCPS

STS

551

P08842
QLYIASLAWPQNCCV

SMCR5

86

Q8TEV8
FEKNVQGSIPCCFSW

SGMS2

321

Q8NHU3
VTPVKNQGQCGSCWA

CTSL

126

P07711
CKQCGKTFNWPISLR

ZNF555

426

Q8NEP9
KQCGKAFSWPELLQQ

ZNF555

511

Q8NEP9
AALWKLPCIFICENN

PDHA1

211

P08559
LVCTFPAGLWFCIKN

STT3B

421

Q8TCJ2
CYWENQPTGCQKLNC

ZC3H11A

66

O75152
QRWCADPALLNCLKQ

UBR1

1566

Q8IWV7
GCFKQWLKGQSACPA

TTC3

1981

P53804
VCNVGWQGLRCDQKI

STAB1

1401

Q9NY15
WQGLRCDQKITSPQC

STAB1

1406

Q9NY15
LFSLNILGCCQGRNW

VPS45

136

Q9NRW7
PCIQGCHFWNSVDQK

ROS1

56

P08922
CKWNNTGCQALPSQD

PIGR

496

P01833
ENNWSLFKLTCNKPC

PRAG1

986

Q86YV5
TCAKPREQQCGFFQW

TOP3A

921

Q13472
GDNQACKPWTNCTLA

TNFRSF4

136

P43489
CYWENQPTGCQKLNC

ZC3H11B

66

A0A1B0GTU1
LAQNPFICDCNLKWL

SLIT1

436

O75093
PAEQAFWCLVQICEK

TBC1D10A

211

Q9BXI6
WTILNALQKTLQCCG

TSPAN19

141

P0C672
PNFQTLKCRWKNCDA

ZNF106

1841

Q9H2Y7
SCQKCEQPFFWNIKQ

WDFY1

286

Q8IWB7
QSCPGARKCINYQWV

TBRG1

306

Q3YBR2
RVVQKDGNSCAWCPQ

USP6

956

P35125
CQDCKVQGPNLWACL

USP33

61

Q8TEY7
CFWPVGIAAFCLAQK

TMEM91

106

Q6ZNR0
CLKTKGPALWQDNFC

ZNF560

181

Q96MR9
SCKLIQCWGQQEFAI

TMC7

526

Q7Z402
NGFEVQKQNCCWLLV

TYW3

61

Q6IPR3
LQMKFVCGQCWRNGQ

ZC3H7B

691

Q9UGR2
ITCFQSTCKPNQICW

ZAN

1901

Q9Y493
QCAQWLIHCKVLPTN

VAV3

6

Q9UKW4
DFVCNNGQCVPSRWK

VLDLR

76

P98155
LNNLGFKICPCGWHQ

GLYATL2

271

Q8WU03
CQGSPWHQFALKLSC

KLRB1

31

Q12918
TNNWVQCNDAPVKIC

MYOM2

426

P54296