Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRB PTPRC PTPRD

3.75e-0517783GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRB PTPRC PTPRD

3.75e-0517783GO:0019198
GeneOntologyBiologicalProcessadherens junction maintenance

PKP2 FERMT2 PLEKHA7

4.13e-069773GO:0034334
GeneOntologyBiologicalProcesscell junction maintenance

CADM1 PRICKLE1 PKP2 FERMT2 PLEKHA7

4.41e-0665775GO:0034331
GeneOntologyBiologicalProcesscellular component maintenance

CADM1 PRICKLE1 PKP2 FERMT2 PLEKHA7

3.81e-05101775GO:0043954
GeneOntologyBiologicalProcessregulation of integrin activation

SELP FERMT1 FERMT2

5.45e-0520773GO:0033623
GeneOntologyBiologicalProcessD-xylose metabolic process

UXS1 XYLB

8.21e-054772GO:0042732
GeneOntologyBiologicalProcesscell-cell junction maintenance

PKP2 FERMT2 PLEKHA7

8.40e-0523773GO:0045217
GeneOntologyBiologicalProcesswound healing

SELP TPSD1 CELSR1 DST ANXA2P2 FERMT1 CD109 PAK1 FERMT2

9.03e-05493779GO:0042060
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

DST BST1 FERMT1 IKBKB FERMT2

1.01e-04124775GO:0007229
GeneOntologyBiologicalProcessregulation of cell junction assembly

DLC1 PTPRD PRICKLE1 RTN4R PKP2 IKBKB FERMT2

1.55e-04309777GO:1901888
GeneOntologyBiologicalProcessregulation of response to wounding

TPSD1 ANXA2P2 RTN4R FERMT1 CD109 FERMT2

1.61e-04217776GO:1903034
GeneOntologyBiologicalProcessresponse to wounding

SELP TPSD1 CELSR1 DST ANXA2P2 RTN4R FERMT1 CD109 PAK1 FERMT2

1.65e-046597710GO:0009611
GeneOntologyBiologicalProcessintegrin activation

SELP FERMT1 FERMT2

1.70e-0429773GO:0033622
GeneOntologyBiologicalProcesspositive regulation of wound healing, spreading of epidermal cells

FERMT1 FERMT2

2.04e-046772GO:1903691
GeneOntologyBiologicalProcesscell junction organization

CADM1 DLC1 DST PTPRD PRICKLE1 RTN4R PAK1 CNTNAP4 PKP2 IKBKB FERMT2 PLEKHA7

2.48e-049747712GO:0034330
GeneOntologyBiologicalProcesscell junction assembly

CADM1 DLC1 DST PTPRD PRICKLE1 RTN4R PKP2 IKBKB FERMT2

2.64e-04569779GO:0034329
GeneOntologyBiologicalProcessregulation of protein modification process

GH2 DCUN1D1 CADM1 PTPRB DLC1 PTPRC PRICKLE1 BST1 ANXA2P2 CD109 PAK1 KNDC1 IKBKB FERMT2 FAM20A

3.48e-0414887715GO:0031399
GeneOntologyBiologicalProcessprotein dephosphorylation

PTPRB DLC1 PTPRC PTPRD IKBKB PPM1A

3.91e-04256776GO:0006470
GeneOntologyBiologicalProcessregulation of wound healing

TPSD1 ANXA2P2 FERMT1 CD109 FERMT2

3.94e-04166775GO:0061041
DomainPTPc

PTPRB PTPRC PTPRD

4.04e-0436753SM00194
DomainARM-type_fold

RANBP17 IPO8 PIK3C2G DOCK8 RTTN NCAPD2 PKP2

4.20e-04339757IPR016024
DomainTYR_PHOSPHATASE_PTP

PTPRB PTPRC PTPRD

5.12e-0439753PS50055
DomainPTPase_domain

PTPRB PTPRC PTPRD

5.94e-0441753IPR000242
DomainY_phosphatase

PTPRB PTPRC PTPRD

5.94e-0441753PF00102
DomainARM-like

RANBP17 IPO8 DOCK8 RTTN NCAPD2 PKP2

7.55e-04270756IPR011989
DomainIBN_N

RANBP17 IPO8

1.62e-0315752PF03810
DomainPTPc_motif

PTPRB PTPRC PTPRD

1.72e-0359753SM00404
DomainTyr_Pase_cat

PTPRB PTPRC PTPRD

1.72e-0359753IPR003595
DomainIBN_N

RANBP17 IPO8

1.84e-0316752SM00913
Domain-

RANBP17 IPO8 RTTN NCAPD2 PKP2

1.99e-032227551.25.10.10
DomainImportin-beta_N

RANBP17 IPO8

2.08e-0317752IPR001494
DomainTyr_Pase_AS

PTPRB PTPRC PTPRD

3.16e-0373753IPR016130
Pubmed

Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems.

RTN4R RTN2 PPM1A

6.27e-07879314664809
Pubmed

UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome.

FERMT1 FERMT2

5.09e-06279227798104
Pubmed

Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.

FERMT1 FERMT2

5.09e-06279221356350
Pubmed

Human hepatic progenitor cells express hematopoietic cell markers CD45 and CD109.

PTPRC CD109

5.09e-06279224396288
Pubmed

Differential expression of Kindlin-1 and Kindlin-2 correlates with esophageal cancer progression and epidemiology.

FERMT1 FERMT2

5.09e-06279228667517
Pubmed

Opposite role of Kindlin-1 and Kindlin-2 in lung cancers.

FERMT1 FERMT2

1.53e-05379223209705
Pubmed

Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.

FERMT1 FERMT2

1.53e-05379218528435
Pubmed

The role of kindlins in cell biology and relevance to human disease.

FERMT1 FERMT2

1.53e-05379219854292
Pubmed

Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases.

PTPRB PTPRC

1.53e-0537921373652
Pubmed

Genome-wide association study of copy number variations (CNVs) with opioid dependence.

PTPRC PTPRD

1.53e-05379225345593
Pubmed

URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.

FERMT1 FERMT2

1.53e-05379212697302
Pubmed

The Kindlins: subcellular localization and expression during murine development.

FERMT1 FERMT2

1.53e-05379216876785
Pubmed

Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.

FERMT1 FERMT2

1.53e-05379212789646
Pubmed

PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.

IKBKB PPM1A

1.53e-05379218930133
Pubmed

Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal.

VRK1 PPM1A

1.53e-05379228911860
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FSIP2 DLC1 DST RALGAPB PKP2 ALPK1 PLEKHA7 CNOT4 PPM1A DOP1A

2.53e-05861791036931259
Pubmed

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail.

FERMT1 FERMT2

3.05e-05479222561348
Pubmed

Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans.

SELP PTPRC

3.05e-05479222387552
Pubmed

Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics.

FERMT1 FERMT2

3.05e-05479224165133
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

PTPRB PRICKLE1 EML6 PCNX1 PLEKHA7 PPM1A DOP1A

4.89e-0542079728065597
Pubmed

Tyrosine sulfation of native mouse Psgl-1 is required for optimal leukocyte rolling on P-selectin in vivo.

SELP PTPRC

5.07e-05579221633705
Pubmed

A novel role for IkappaB kinase (IKK) alpha and IKKbeta in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae.

IKBKB MUC5AC

5.07e-05579217237423
Pubmed

Pooled genetic analysis reveals an association of SNPs of only a few genes with risk predisposition to ischemic stroke in a Chinese population.

CELSR1 XYLB

5.07e-05579225855559
Pubmed

Genetic mapping of the gene encoding the alpha1 subunit of neuronal calcium channels.

SELP PTPRC

5.07e-0557928661716
Pubmed

Organogenesis of the liver, thymus and spleen is affected in jumonji mutant mice.

SELP PTPRC

5.07e-0557929376320
Pubmed

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.

FERMT1 FERMT2

5.07e-05579226821125
Pubmed

Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

PTPRB PTPRC

5.07e-0557922169617
Pubmed

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.

DOCK8 PAK1

7.60e-05679222581261
Pubmed

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

PTPRB PTPRD

7.60e-0567922170109
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRB PTPRC

1.06e-0477921454056
Pubmed

Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.

CELSR1 PRICKLE1

1.06e-04779217937400
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRC PTPRD

1.06e-04779212376545
Pubmed

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.

FERMT1 FERMT2

1.06e-04779225086068
Pubmed

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK.

NLRX1 IKBKB

1.06e-04779221703539
Pubmed

LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition.

RTN4R ADAM22

1.06e-04779220463223
Pubmed

Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice.

SELP PTPRC

1.06e-04779210749569
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RANBP17 UXS1 PTPRB TESMIN UBE4B PTBP2 RALGAPB KNDC1 XYLB HSD11B2 TET3 DOP1A

1.30e-041489791228611215
Pubmed

Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state.

SELP PTPRC

1.41e-04879218086862
Pubmed

Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.

MUC5AC TET3

1.41e-04879236539616
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYT1L DST RALGAPB PCNX1 ALPK1

1.66e-0422579512168954
Pubmed

The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration.

PTPRC MUC5AC

1.82e-04979230923168
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRB PTPRD

2.76e-04117927832766
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRC PTPRD

3.31e-04127929624153
Pubmed

Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture.

FERMT1 FERMT2

3.31e-041279230883226
Pubmed

Microtubules enable the planar cell polarity of airway cilia.

CELSR1 PRICKLE1

3.31e-041279223122850
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

VRK1 DOCK8 PTBP2 FERMT1 NCAPD2 PAK1 KIF4A

3.63e-0458279720467437
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

CELSR1 TET3

3.91e-041379226989192
Pubmed

PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.

PAK1 PPM1A

4.55e-041479218586681
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

PTPRD CNTNAP4

4.55e-041479224811271
Pubmed

Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants.

HMGB4 PPM1A

5.25e-041579220970119
Pubmed

Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.

FERMT1 FERMT2

5.25e-041579226151572
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

CADM1 DLC1 PTPRD DOCK8 RTN4R CD109 PKP2 CPVL

5.25e-0481479823251661
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DST DOCK8 RALGAPB PKP2 PLEKHA7 CPVL

5.43e-0444679624255178
Pubmed

Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos.

RTTN DNAH11

5.99e-041679211900971
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PTPRC PIK3C2G

5.99e-041679216524887
Pubmed

Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm.

SELP IPO8

5.99e-041679212781685
Pubmed

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

PIK3C2G IKBKB

5.99e-041679221029719
Pubmed

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.

CELSR1 PRICKLE1

5.99e-041679222771245
Pubmed

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.

CELSR1 PRICKLE1

6.78e-041779228292423
Pubmed

A genetic analysis of neural progenitor differentiation.

ANXA2P2 FERMT2

6.78e-041779211239426
Pubmed

Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.

PTPRC MUC5AC

8.50e-041979217855428
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

MYT1L CELSR1 CADM1

8.78e-048279331073041
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CELSR1 DST REPS1 UBE4B NLRX1 RTTN NCAPD2 PCNX1 CPVL

8.96e-04110579935748872
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DST UBE4B TAF1B FERMT1 NCAPD2 PKP2 KIF4A RRM1 FERMT2 NDUFB4

9.66e-041353791029467282
Pubmed

Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.

CELSR1 PRICKLE1

1.04e-032179218701545
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DLC1 REPS1 IPO8 DOCK8 PAK1 PKP2 PLEKHA7 CPVL

1.13e-0391679832203420
Pubmed

USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.

CELSR1 PRICKLE1

1.14e-032279235440748
Pubmed

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.

ALPK1 IKBKB

1.14e-032279236098982
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

VRK1 PTBP2 ANXA2P2 KIF4A

1.20e-0320379422083510
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DST DOCK8 ANXA2P2 SLC27A1 KNDC1 FERMT2 PLEKHA7 NDUFB4 ADAM22 DNAH11

1.47e-031431791037142655
Pubmed

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

PTPRC CD109

1.48e-032579219898481
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

SELP PTPRB TAS1R2

1.60e-0310179323382219
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DLC1 KNDC1 CNTNAP4

1.65e-0310279311214970
Pubmed

Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.

PTPRC MUC5AC

1.72e-032779232878924
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

CADM1 PTPRD

1.85e-032879233953184
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

PRPSAP1 REPS1 NCAPD2 CPVL CEP97 PPM1A

1.93e-0357179637167062
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DST TESMIN TET3 DNAH11

1.99e-0323379437704626
Pubmed

Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.

NCAPD2 RRM1

2.13e-033079216420439
Pubmed

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.

DST PAK1

2.13e-033079224472646
Pubmed

Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.

DLC1 PAK1

2.13e-033079220083228
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

DST PAK1 PKP2 ZMYM1 IKBKB

2.23e-0340179525852190
Cytoband8p11.21

GOLGA7 SMIM19

6.01e-04217928p11.21
CytobandEnsembl 112 genes in cytogenetic band chr8p11

GOLGA7 IKBKB SMIM19

7.66e-04103793chr8p11
Cytoband17q24.2

GH2 FAM20A

1.23e-033079217q24.2
GeneFamilyFermitins|Pleckstrin homology domain containing|FERM domain containing

FERMT1 FERMT2

2.07e-053482561
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRB PTPRC PTPRD

2.26e-0521483813
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

PTPRC DOCK8 PCNX1 FAM20A CPVL MS4A4E TET3

5.07e-08194787ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.01e-06189786c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.01e-06189786fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

RANBP17 CADM1 DLC1 PTPRD FAM20A RTN2

1.11e-06192786356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

PTPRC DOCK8 PCNX1 FAM20A MS4A4E TET3

1.15e-061937865fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

PTPRC DOCK8 FAM20A CPVL MS4A4E TET3

1.22e-061957865e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRC DOCK8 PAK1 CPVL MS4A4E TET3

1.25e-06196786cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MGAM PTPRC PAK1 LIPK CPVL MS4A4E

1.29e-06197786363ae03310f63a586ba3cea2a59f35d5a335a54e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G EML6 HSD11B2 FAM20A

6.06e-06147785b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRC NCAPD2 KIF4A RRM1 CEP97

1.06e-05165785ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PTPRB EML6 FAM227A DOP1A

1.13e-05167785774f3264318b002d0df5d06d41d645366038d0bf
ToppCell10x5'-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

TPSD1 DLC1 FERMT2 MS4A4E RTN2

1.16e-05168785650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell10x5'-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

TPSD1 DLC1 FERMT2 MS4A4E RTN2

1.16e-05168785e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

RANBP17 PTPRD TESMIN FERMT1 CD109

1.16e-0516878590b33962adb77d8326dee403712118398b4d1315
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

RANBP17 PTPRD TESMIN FERMT1 CD109

1.23e-0517078585c476e0bc496445e868a88849960598d97bdea2
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

RANBP17 CADM1 DLC1 DST FERMT2

1.23e-05170785e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2|lymph-node_spleen / Manually curated celltypes from each tissue

DST PAK1 CPVL MS4A4E MUC5AC

1.45e-0517678572a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP BST1 NCAPD2 RRM1 ATPAF1

1.49e-051777851d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 PIK3C2G HSD11B2 FERMT2 ADAM22

1.57e-05179785666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 PRICKLE1 PIK3C2G EML6 FAM20A

1.57e-05179785d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

MGAM PTPRC DOCK8 CPVL MS4A4E

1.62e-0518078525ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 PIK3C2G HSD11B2 FERMT2 ADAM22

1.70e-051827855f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

CADM1 DST PAK1 PKP2 CPVL

1.75e-05183785c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

MGAM PTPRC PAK1 CPVL MS4A4E

1.75e-051837858f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

MGAM PTPRC PAK1 CPVL MS4A4E

1.75e-05183785c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.75e-05183785b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 PIK3C2G HSD11B2 FERMT2 ADAM22

1.75e-051837852e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM PTPRD PIK3C2G CNTNAP4 DNAH11

1.80e-051847852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

CADM1 DST PAK1 PKP2 CPVL

1.80e-0518478542d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM PTPRD PIK3C2G CNTNAP4 DNAH11

1.80e-05184785ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell10x5'-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

CADM1 PKP2 XYLB HSD11B2 CPVL

1.80e-0518478509fa465d1852b9b7e0405c27d4e5de276c9ba871
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM PTPRD PIK3C2G CNTNAP4 DNAH11

1.80e-051847852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.84e-05185785d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G HSD11B2 FAM20A CPVL

1.89e-05186785aeac0c2db173cd1ea45b5052ab418d6cacd198d8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CADM1 PTPRD BST1 ALPK1 FAM20A

1.89e-05186785f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CADM1 PTPRD BST1 ALPK1 FAM20A

1.89e-051867858694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM CELSR1 RTTN XYLB PLEKHA7

1.89e-051867855784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell3'_v3-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

DST CD109 PAK1 CPVL MS4A4E

1.94e-051877859f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.94e-051877852d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.94e-05187785e3095455d2f255854f339f6b05fa87852af0700f
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

RANBP17 CELSR1 CADM1 PLEKHA7 DNAH11

1.99e-05188785c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

1.99e-0518878558ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

2.04e-051897853a295c215b5c18e7c673f92b7af5be523421682c
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRC DOCK8 CPVL MS4A4E TET3

2.04e-051897852586f4088721c5debec86c2b211b739fd33713eb
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTPRC DOCK8 FAM20A CPVL MS4A4E

2.10e-05190785773c55b9e28c2f77a5eb5f0adb0fa9862fb9611d
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MGAM PTPRC DOCK8 BST1 MS4A4E

2.10e-051907856a70d92cf66bdc9dade218b530f040f1581926f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G EML6 HSD11B2 FAM20A ADAM22

2.10e-05190785b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

VRK1 PTPRB RTTN KIF4A RRM1

2.10e-05190785e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CELSR1 PTPRD PRICKLE1 XYLB PLEKHA7

2.15e-051917853c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CELSR1 PTPRD PRICKLE1 XYLB PLEKHA7

2.15e-051917851c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SELP DLC1 PRICKLE1 PKP2 RTN2

2.15e-051917857edc22e7e70697fb22690699efb352577162709b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G EML6 HSD11B2 FAM20A

2.20e-05192785fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MGAM PTPRC DOCK8 BST1 MS4A4E

2.20e-051927850ba5729a890bfba5db567cd0eec7924cd1991ac3
ToppCellFetal_29-31_weeks-Immune-monocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRC DOCK8 PAK1 CPVL MS4A4E

2.20e-051927855417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SELP PTPRB DLC1 PIWIL1 CD109

2.20e-0519278525cb6cc6cbf8dc20139d938adfc02ed7a8c3dfb6
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

RANBP17 CELSR1 CADM1 DLC1 PLEKHA7

2.20e-05192785efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PTPRB DLC1 DST FERMT2

2.20e-05192785452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PTPRB DLC1 DST FERMT2

2.20e-051927857ddaca206599603d4d0b2afb73ed2850225d277d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 CADM1 DLC1 PTPRD PIK3C2G

2.20e-05192785fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G EML6 HSD11B2 FAM20A

2.20e-05192785bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PTPRB DLC1 DST FERMT2

2.20e-05192785bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G HSD11B2 FAM20A CPVL

2.26e-05193785371f4c98a599923fbe8382530b3eab05d873665a
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRC DOCK8 PAK1 CPVL MS4A4E

2.26e-0519378558e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELP PTPRB DLC1 CD109 FAM20A

2.26e-05193785c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 PTPRB DLC1 PRICKLE1 FERMT2

2.26e-05193785ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 PIK3C2G EML6 HSD11B2 CPVL

2.32e-051947854579b4a44f7c731553a284843c296866027d7c0e
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM1 PTPRB DLC1 PRICKLE1 FERMT2

2.32e-05194785ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

PTPRC DOCK8 FAM20A MS4A4E TET3

2.32e-05194785c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PTPRC DOCK8 FAM20A CPVL MS4A4E

2.32e-05194785a062100ea6cd512a108f9036c259e0cd0f458563
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM CADM1 PIK3C2G HSD11B2 FAM20A

2.32e-0519478569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCUN1D1 PIK3C2G HSD11B2 FAM20A CPVL

2.32e-05194785158dc393639e69aecfb014f6106797214ea05fe5
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM1 PTPRB DLC1 PRICKLE1 FERMT2

2.32e-05194785627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

PTPRC DOCK8 PAK1 CPVL MS4A4E

2.37e-05195785ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

PTPRC DOCK8 CPVL MS4A4E TET3

2.37e-05195785148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SELP DLC1 PRICKLE1 PKP2 RTN2

2.37e-051957859b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELP DLC1 PRICKLE1 PKP2 RTN2

2.37e-051957851e794839a251fbc6e6ce419b4c457ead35a04735
ToppCellwk_15-18-Hematologic-Myeloid-DC2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PTPRC DOCK8 PAK1 CPVL MS4A4E

2.37e-05195785143093edefb3da63bb10adb1f5ea6e250a524ac2
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

MGAM PTPRC DOCK8 CPVL TET3

2.43e-0519678504d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRC DOCK8 CPVL MS4A4E TET3

2.43e-051967857026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRC DOCK8 CPVL MS4A4E TET3

2.49e-05197785e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

PTPRC DOCK8 CPVL MS4A4E TET3

2.49e-051977853896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell(3)_DC_Monocyte_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCAPD2 PAK1 KIF4A RRM1 CPVL

2.55e-05198785e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 CELSR1 CADM1 FAM20A PLEKHA7

2.61e-051997855f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 CADM1 DLC1 FAM20A PLEKHA7

2.61e-051997858587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 CELSR1 CADM1 FAM20A PLEKHA7

2.61e-051997855cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSD1 PTPRC DOCK8 CPVL MS4A4E

2.68e-05200785ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MGAM PTPRC PAK1 CPVL MS4A4E

2.68e-05200785f19b729b03b5f225b9ed676f0ac31071a4354da3
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 CADM1 PKP2 FAM20A PLEKHA7

2.68e-052007857c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM PTPRB PCNX1 FERMT2

1.13e-04142784191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MGAM PTPRB PCNX1 FERMT2

1.16e-04143784b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MGAM PTPRC BST1 NLRX1

1.23e-04145784ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MGAM PTPRC BST1 NLRX1

1.23e-041457842beb4ea3838796c580076ab7769de877a3a0552c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TESMIN PIK3C2G EML6 HSD11B2

1.26e-04146784e887e9de895fd453faa703997ef372cc6410fc49
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PTPRC PKP2 ALPK1 HSD11B2

1.33e-04148784a261c6d3d9cf0311c053fca66c37d39e66db6ad8
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VRK1 UXS1 PTPRC PAK1

1.33e-041487843f48f5ba0a0928ddf6da7a1be1976933921f42ad
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like-IPs_and_early_cortical_neurons|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PTPRC PKP2 ALPK1 HSD11B2

1.33e-04148784c0237ba7d4040b6a497094b362dfb8b3a97a7d06
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_dendritic_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CADM1 PKP2 FAM227A CPVL

1.36e-0414978471d72a6e7b128ee96161e08f6a0d77be925e73a1
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSD1 DLC1 CD109 MS4A4E

1.47e-0415278432634195048858ae84605c61e43c542d90f7cab5
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSD1 DLC1 CD109 MS4A4E

1.47e-041527840eb185b2404f015efff1bd140e0c502d714720fb
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PAK1 CPVL MS4A4E ZNF433

1.47e-041527840769857f25da2e6169420818e61d65e33b7277b1
Drugmono-(2-ethylhexyl)phthalate

RANBP17 CADM1 DST PTPRD TESMIN PIK3C2G SLC27A1 MAGEB18 CD109 KNDC1 HSD11B2 ADAM22

2.03e-066587712ctd:C016599
DiseaseAngle Closure Glaucoma

FERMT2 PLEKHA7

1.47e-047792C0017605
Diseaseendometrial carcinoma

DLC1 PTPRD PAK1 CPVL

2.46e-04113794EFO_1001512
Diseaseunipolar depression, anorexia nervosa

CADM1 PTBP2

3.14e-0410792EFO_0003761, MONDO_0005351
Diseaseprimary angle closure glaucoma

FERMT2 PLEKHA7

3.83e-0411792EFO_1001506
Diseasebitter alcoholic beverage consumption measurement

MGAM PTPRD XYLB TET3

4.56e-04133794EFO_0010092
DiseaseNeurobehavioral Manifestations

SELP UBE4B

4.59e-0412792C0525041
Diseaseunipolar depression, response to selective serotonin reuptake inhibitor, mood disorder

MYT1L TAF1B

9.38e-0417792EFO_0003761, EFO_0004247, EFO_0005658
DiseaseLung diseases

DOCK8 BST1 DNAH11

1.22e-0378793C0024115
DiseaseIntellectual Disability

MYT1L VRK1 DOCK8 RTTN KIF4A TET3

1.28e-03447796C3714756
Diseaselongitudinal BMI measurement

PTPRD PIK3C2G PKP2

1.40e-0382793EFO_0005937
Diseasealcohol consumption measurement

MYT1L RANBP17 MGAM VRK1 PTPRB FAM227A XYLB ALPK1 TET3 CNOT4

1.73e-0312427910EFO_0007878
DiseaseSjogren's syndrome (is_marker_for)

SELP MUC5AC

1.88e-0324792DOID:12894 (is_marker_for)
Diseasediet measurement

MYT1L GH2 RANBP17 MGAM DST PTBP2 ALPK1 SMIM19 CNOT4

1.94e-031049799EFO_0008111
DiseaseNeurodevelopmental Disorders

MYT1L DOCK8 PAK1

2.02e-0393793C1535926
Diseaseatopic dermatitis (is_implicated_in)

SELP DOCK8

2.21e-0326792DOID:3310 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
FRKELEYQANNQYIP

UXS1

391

Q8NBZ7
YQPNKELQNNLFDRI

FAM227A

206

F5H4B4
QYSCINDYRPVKLLQ

BST1

256

Q10588
NPKYDAVRINQLYEQ

FERMT1

281

Q9BQL6
KNYREQRQLPQGDYV

ADAM22

761

Q9P0K1
LQIRYKLNKYQEPDV

CNTNAP4

1076

Q9C0A0
YFVINDLQKINPLYQ

DNAH11

3716

Q96DT5
DQYQKYLPDIQERLV

DOP1A

2191

Q5JWR5
LALPLDYKQEQQYVL

CELSR1

746

Q9NYQ6
NLPQELLQAYGKDYI

HSD11B2

286

P80365
QRIQNKPLYFADQLY

ANXA2P2

261

A6NMY6
EQLYNRYKDPQDENK

DCUN1D1

66

Q96GG9
NKRLYEQNIPTQIFY

ALPK1

1096

Q96QP1
YIQEQNEKIYAPQGL

GOLGA7

96

Q7Z5G4
RNYILNYVASQPKLA

RANBP17

86

Q9H2T7
IQDLKYVYNNLRPQD

PIK3C2G

1131

O75747
ENRGKNRYNNILPYD

PTPRB

1726

P23467
NRYNNILPYDATRVK

PTPRB

1731

P23467
KDLVQLKYLEYQQVP

MAGEB18

246

Q96M61
LQYLAPELLEQQKYT

IKBKB

186

O14920
NNPVELKALYNQYLQ

DST

301

Q03001
LQFKIYDPNNNRYEV

MGAM

1946

O43451
DLDLEIQKIYPYQNN

FSIP2

2366

Q5CZC0
IQKIYPYQNNILFQE

FSIP2

2371

Q5CZC0
NNYKVLIYNGQLDII

CPVL

376

Q9H3G5
PLLKTLEYNQYEVRN

PCNX1

1326

Q96RV3
NKNQLPPICYNYEIR

MUC5AC

2026

P98088
NLQKLYFQLRLNQPY

NLRX1

316

Q86UT6
AQLKREYLLQYNDPN

NDUFB4

41

O95168
LRLYTPDNYEKFIQN

PRICKLE1

701

Q96MT3
ENKNPNIVNYLDSYL

PAK1

321

Q13153
LQTQRYLEVQYKPQV

CADM1

231

Q9BY67
LLGYRKYQPNIDVQE

CD109

1056

Q6YHK3
NLLYVYPQRLNFVNK

DOCK8

561

Q8NF50
LQANPFYDRYRDKIQ

ATPAF1

71

Q5TC12
NYNPQAKDVRYEIRL

CEP97

576

Q8IW35
YPIELDKLQNLVVNY

CCDC183

186

Q5T5S1
MYPYQLQQELEQQKV

MS4A4E

91

Q96PG1
QNKNEIDYLNKVLPY

SELP

71

P16109
QPIQYQYQDNIKELE

KIF4A

551

O95239
FLLQYIQEEIPNYRN

PRPSAP1

156

Q14558
PNYVQDKYLLQLLRN

KNDC1

1526

Q76NI1
YDRQVYKEDLPQLKQ

EML6

641

Q6ZMW3
DLNPKYDAIRINQLY

FERMT2

281

Q96AC1
PARNLYAYIQKLTQI

PTPRD

1621

P23468
QYRQKEYVAPRVLQQ

IPO8

311

O15397
YQDQNNYLQSDVPKP

TESMIN

241

Q9Y4I5
YRKQYNQEITDLKQP

PIWIL1

346

Q96J94
LQYLYLQDNALQALP

RTN4R

156

Q9BZR6
IPLLYRQHQAQIDQY

RTN2

491

O75298
NPLNAYYLKCLENLV

RTTN

2206

Q86VV8
QLREQHLYYQDQLLP

TPSD1

96

Q9BZJ3
RQYYVNQFKTIQPDL

REPS1

286

Q96D71
AELNDYVKLANLPYQ

PRSS58

111

Q8IYP2
LRNQPIYIQYSNHKE

PTBP2

121

Q9UKA9
QYILYQQAEALKNLG

TAF1B

81

Q53T94
VKQIYPYNNSQRLLN

FAM20A

381

Q96MK3
LNYRNKFKEQQPNTY

HMGB4

21

Q8WW32
YRDQPQHLEKIAYQQ

PLEKHA7

736

Q6IQ23
NPKYVLRNYIAQNAI

SELENOO

591

Q9BVL4
LQIYQYVPKDQRLQA

DLC1

1171

Q96QB1
EAVLNAYRQLYLNPK

NCAPD2

691

Q15021
YEQKLLQELYKLNPN

CNOT4

236

O95628
YILKEQKYSFLQNPQ

GH2

61

P01242
NVIEAVYNRLNPYKN

PPM1A

356

P35813
NLNKIIDINYYPVPE

RRM1

476

P23921
NAIYQELQKVLAPYA

SLC27A1

566

Q6PCB7
NQNYIRNPYLVAKLV

UBE4B

921

O95155
ISRKYDYQQPQNQAD

SMIM19

86

Q96E16
QVYEALLPQYAKLEQ

XYLB

511

O75191
LYKRLAPQAYQNQVT

TET3

1031

O43151
IVNKYRNKQLEPEFY

RALGAPB

1466

Q86X10
ASYYPLQRQLKNIQD

TAS1R2

466

Q8TE23
SNLLLNYKNPDQVYL

VRK1

181

Q99986
NIYYQGLDTILQNLK

ZMYM1

966

Q5SVZ6
FNQNKNRYVDILPYD

PTPRC

676

P08575
KNRNSNVIPYDYNRV

PTPRC

971

P08575
KPQNIYVEYENLRRN

ZNF433

51

Q8N7K0
ELPEKYSQNIYIQNR

PKP2

621

Q99959
KDQYPNYDQRLNLAE

TPRX2

41

P0DV77
VENLLPQIANLIYYK

LIPK

351

Q5VXJ0
VKQLEIPQYGYRNNV

MYT1L

611

Q9UL68