Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R20 TAS2R30 TAS2R33 TAS2R36	3.80e-07	27	45	4	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R20 TAS2R30 TAS2R33 TAS2R36	8.78e-07	33	45	4	GO:0008527
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	LMBR1 CCR10 OR2A25 OR2T10 TAS2R20 TAS2R30 ITGB2 TAS2R33 TAS2R36 AGTRAP OR4F6 LILRB4	3.15e-05	1353	45	12	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	CCR10 OR2A25 OR2T10 TAS2R20 TAS2R30 TAS2R33 TAS2R36 AGTRAP OR4F6	1.32e-04	884	45	9	GO:0004930
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of bitter taste	TAS2R20 TAS2R30 TAS2R33 TAS2R36	2.09e-06	44	43	4	GO:0001580
GeneOntologyBiologicalProcess	sensory perception of bitter taste	TAS2R20 TAS2R30 TAS2R33 TAS2R36	2.98e-06	48	43	4	GO:0050913
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of taste	TAS2R20 TAS2R30 TAS2R33 TAS2R36	3.52e-06	50	43	4	GO:0050912
GeneOntologyBiologicalProcess	sensory perception of taste	TAS2R20 TAS2R30 TAS2R33 TAS2R36	1.36e-05	70	43	4	GO:0050909
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2A25 OR2T10 TAS2R20 TAS2R30 COMT TAS2R33 TAS2R36 OR4F6	2.32e-05	582	43	8	GO:0050906
GeneOntologyBiologicalProcess	negative regulation of dopamine metabolic process	COMT ITGB2	4.23e-05	5	43	2	GO:0045963
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2A25 OR2T10 TAS2R20 TAS2R30 TAS2R33 TAS2R36 OR4F6	5.89e-05	485	43	7	GO:0050907
GeneOntologyBiologicalProcess	negative regulation of catecholamine metabolic process	COMT ITGB2	6.33e-05	6	43	2	GO:0045914
GeneOntologyBiologicalProcess	vitamin E metabolic process	CYP4F2 NPC1L1	6.33e-05	6	43	2	GO:0042360
GeneOntologyBiologicalProcess	lipid transport	CYP4F2 XKR7 EGF COMT ABCA13 ATP10D NPC1L1	7.69e-05	506	43	7	GO:0006869
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2A25 OR2T10 TAS2R20 TAS2R30 TAS2R33 TAS2R36 OR4F6	9.57e-05	524	43	7	GO:0009593
GeneOntologyBiologicalProcess	positive regulation of intracellular protein transport	PTPN5 FLNA PSEN1 EDEM1	9.89e-05	116	43	4	GO:0090316
GeneOntologyBiologicalProcess	detection of stimulus	OR2A25 OR2T10 TAS2R20 TAS2R30 COMT TAS2R33 TAS2R36 OR4F6	1.06e-04	722	43	8	GO:0051606
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2A25 OR2T10 TAS2R20 TAS2R30 TAS2R33 TAS2R36 OR4F6	1.25e-04	547	43	7	GO:0007606
GeneOntologyBiologicalProcess	lipid localization	CYP4F2 XKR7 EGF COMT ABCA13 ATP10D NPC1L1	1.53e-04	565	43	7	GO:0010876
GeneOntologyBiologicalProcess	cholesterol transport	EGF COMT ABCA13 NPC1L1	1.73e-04	134	43	4	GO:0030301
GeneOntologyBiologicalProcess	Notch receptor processing	APH1B PSEN1	1.89e-04	10	43	2	GO:0007220
GeneOntologyBiologicalProcess	positive regulation of protein import into nucleus	PTPN5 FLNA PSEN1	1.94e-04	54	43	3	GO:0042307
GeneOntologyBiologicalProcess	sterol transport	EGF COMT ABCA13 NPC1L1	1.99e-04	139	43	4	GO:0015918
GeneOntologyBiologicalProcess	negative regulation of amine metabolic process	COMT ITGB2	2.31e-04	11	43	2	GO:0033239
GeneOntologyBiologicalProcess	sensory perception	CNNM4 OR2A25 OR2T10 TAS2R20 TAS2R30 COMT TAS2R33 TAS2R36 OR4F6	3.04e-04	1072	43	9	GO:0007600
GeneOntologyBiologicalProcess	positive regulation of transport	PTPN5 FLNA ILDR1 CYP4F2 EGF PSEN1 EDEM1 ITGB2 ABCA13	3.24e-04	1081	43	9	GO:0051050
GeneOntologyBiologicalProcess	positive regulation of intracellular transport	PTPN5 FLNA PSEN1 EDEM1	3.56e-04	162	43	4	GO:0032388
GeneOntologyBiologicalProcess	regulation of protein tyrosine kinase activity	EGF PSEN1 LILRB4	4.02e-04	69	43	3	GO:0061097
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	CCR10 FLNA OR2A25 OR2T10 TAS2R20 TAS2R30 TAS2R33 TAS2R36 AGTRAP OR4F6	4.75e-04	1395	43	10	GO:0007186
GeneOntologyBiologicalProcess	regulation of protein localization to nucleus	PTPN5 FLNA PSEN1 LILRB4	4.88e-04	176	43	4	GO:1900180
GeneOntologyBiologicalProcess	receptor internalization	PTPN5 EGF ITGB2 LILRB4	5.53e-04	182	43	4	GO:0031623
GeneOntologyBiologicalProcess	regulation of intracellular protein transport	PTPN5 FLNA PSEN1 EDEM1	5.53e-04	182	43	4	GO:0033157
GeneOntologyBiologicalProcess	positive regulation of nucleocytoplasmic transport	PTPN5 FLNA PSEN1	5.98e-04	79	43	3	GO:0046824
GeneOntologyBiologicalProcess	regulation of protein import into nucleus	PTPN5 FLNA PSEN1	6.43e-04	81	43	3	GO:0042306
GeneOntologyBiologicalProcess	receptor-mediated endocytosis	PTPN5 EGF PSEN1 ITGB2 LILRB4	6.54e-04	337	43	5	GO:0006898
GeneOntologyBiologicalProcess	short-term memory	APH1B COMT	7.10e-04	19	43	2	GO:0007614
GeneOntologyBiologicalProcess	organic hydroxy compound transport	EGF COMT ABCA13 SLC18B1 NPC1L1	8.58e-04	358	43	5	GO:0015850
GeneOntologyBiologicalProcess	hindbrain development	FLNA EGF PSEN1 COMT	9.11e-04	208	43	4	GO:0030902
GeneOntologyCellularComponent	endoplasmic reticulum membrane	PTPN5 CERS5 APH1B OR2A25 CYP4F2 FADS1 PSEN1 EDEM1 PIGO ATP10D AGTRAP	8.69e-05	1293	46	11	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	PTPN5 CERS5 APH1B OR2A25 CYP4F2 FADS1 PSEN1 EDEM1 PIGO ATP10D AGTRAP	9.06e-05	1299	46	11	GO:0098827
GeneOntologyCellularComponent	gamma-secretase complex	APH1B PSEN1	9.88e-05	7	46	2	GO:0070765
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	PTPN5 CERS5 APH1B OR2A25 CYP4F2 FADS1 PSEN1 EDEM1 PIGO ATP10D AGTRAP	1.10e-04	1327	46	11	GO:0042175
GeneOntologyCellularComponent	cell cortex	FLNA FLNB PSEN1 SPTB AGTRAP	1.29e-03	371	46	5	GO:0005938
HumanPheno	Fibular aplasia	LMBR1 FLNA FLNB	2.12e-06	11	13	3	HP:0002990
HumanPheno	Accessory carpal bones	FLNA FLNB	6.01e-06	2	13	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	6.01e-06	2	13	2	HP:0008127
HumanPheno	Tarsal synostosis	LMBR1 FLNA FLNB	3.26e-05	26	13	3	HP:0008368
HumanPheno	Aplasia/Hypoplasia of the fibula	LMBR1 FLNA FLNB	5.60e-05	31	13	3	HP:0006492
HumanPheno	Synostosis involving bones of the feet	LMBR1 FLNA FLNB	6.17e-05	32	13	3	HP:0009140
HumanPheno	Synostosis involving bones of the lower limbs	LMBR1 FLNA FLNB	6.17e-05	32	13	3	HP:0009138
HumanPheno	Short humerus	LMBR1 FLNA FLNB	6.17e-05	32	13	3	HP:0005792
HumanPheno	Aplasia/hypoplasia of the humerus	LMBR1 FLNA FLNB	6.78e-05	33	13	3	HP:0006507
HumanPheno	Spondylolysis	FLNA FLNB	8.97e-05	6	13	2	HP:0003304
HumanPheno	Carpal synostosis	LMBR1 FLNA FLNB	1.13e-04	39	13	3	HP:0009702
HumanPheno	Abnormal patella morphology	LMBR1 FLNA FLNB COMT	1.22e-04	109	13	4	HP:0003045
HumanPheno	Limited knee flexion/extension	FLNA FLNC	1.25e-04	7	13	2	HP:0005085
HumanPheno	Limited knee flexion	FLNA FLNC	1.25e-04	7	13	2	HP:0006389
HumanPheno	Broad phalanges of the thumb	FLNA FLNB	1.67e-04	8	13	2	HP:0009651
HumanPheno	Synostosis of carpals/tarsals	LMBR1 FLNA FLNB	2.38e-04	50	13	3	HP:0100266
HumanPheno	Abnormality of the capitate bone	FLNA FLNB	3.91e-04	12	13	2	HP:0004262
HumanPheno	Abnormality of the hamate bone	FLNA FLNB	3.91e-04	12	13	2	HP:0004259
HumanPheno	Capitate-hamate fusion	FLNA FLNB	3.91e-04	12	13	2	HP:0001241
HumanPheno	Abnormal fibula morphology	LMBR1 FLNA FLNB	4.50e-04	62	13	3	HP:0002991
HumanPheno	Aplasia/Hypoplasia of metatarsal bones	LMBR1 FLNA FLNB	5.42e-04	66	13	3	HP:0001964
HumanPheno	Synostosis involving bones of the hand	LMBR1 FLNA FLNB	5.66e-04	67	13	3	HP:0004278
HumanPheno	Abnormality of the humerus	LMBR1 FLNA FLNB	5.91e-04	68	13	3	HP:0003063
Domain	Actinin_actin-bd_CS	FLNA FLNB FLNC SPTB	1.55e-07	23	40	4	IPR001589
Domain	ACTININ_2	FLNA FLNB FLNC SPTB	1.55e-07	23	40	4	PS00020
Domain	ACTININ_1	FLNA FLNB FLNC SPTB	1.55e-07	23	40	4	PS00019
Domain	IG_FLMN	FLNA FLNB FLNC	1.08e-06	10	40	3	SM00557
Domain	Filamin	FLNA FLNB FLNC	1.48e-06	11	40	3	PF00630
Domain	Filamin/ABP280_rpt	FLNA FLNB FLNC	1.48e-06	11	40	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB FLNC	1.48e-06	11	40	3	IPR017868
Domain	FILAMIN_REPEAT	FLNA FLNB FLNC	1.48e-06	11	40	3	PS50194
Domain	CH	FLNA FLNB FLNC SPTB	1.11e-05	65	40	4	SM00033
Domain	CH	FLNA FLNB FLNC SPTB	1.49e-05	70	40	4	PF00307
Domain	-	FLNA FLNB FLNC SPTB	1.58e-05	71	40	4	1.10.418.10
Domain	CH	FLNA FLNB FLNC SPTB	1.76e-05	73	40	4	PS50021
Domain	CH-domain	FLNA FLNB FLNC SPTB	1.96e-05	75	40	4	IPR001715
Domain	TAS2R	TAS2R20 TAS2R30	1.41e-03	26	40	2	PF05296
Domain	T2R	TAS2R20 TAS2R30	1.41e-03	26	40	2	IPR007960
Domain	Ig_E-set	FLNA FLNB FLNC	1.43e-03	104	40	3	IPR014756
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNA FLNB FLNC	1.73e-06	11	32	3	M48099
Pathway	REACTOME_SIGNALING_BY_NOTCH3	APH1B EGF PSEN1	1.00e-05	19	32	3	MM15594
Pathway	REACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	APH1B EGF PSEN1	2.36e-05	25	32	3	M27879
Pathway	REACTOME_SIGNALING_BY_ERBB4	APH1B EGF PSEN1	5.53e-05	33	32	3	MM14523
Pathway	REACTOME_SIGNALING_BY_NOTCH	APH1B EGF PSEN1	9.19e-05	39	32	3	MM14604
Pathway	REACTOME_NONCANONICAL_ACTIVATION_OF_NOTCH3	APH1B PSEN1	1.04e-04	7	32	2	MM15612
Pathway	REACTOME_NONCANONICAL_ACTIVATION_OF_NOTCH3	APH1B PSEN1	1.39e-04	8	32	2	M27887
Pathway	REACTOME_SIGNALING_BY_NOTCH3	APH1B EGF PSEN1	1.82e-04	49	32	3	M618
Pathway	WP_MAPK_SIGNALING	PTPN5 FLNA FLNB FLNC EGF	2.13e-04	246	32	5	M39597
Pathway	REACTOME_TGFBR3_PTM_REGULATION	APH1B PSEN1	2.22e-04	10	32	2	MM17232
Pathway	REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR	APH1B PSEN1	2.22e-04	10	32	2	MM14744
Pathway	REACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	APH1B PSEN1	2.71e-04	11	32	2	M27882
Pathway	REACTOME_TGFBR3_PTM_REGULATION	APH1B PSEN1	2.71e-04	11	32	2	M48251
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION	APH1B PSEN1	2.71e-04	11	32	2	M47865
Pathway	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	APH1B PSEN1	2.71e-04	11	32	2	MM14534
Pathway	REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR	APH1B PSEN1	2.71e-04	11	32	2	M2661
Pathway	REACTOME_SIGNALING_BY_ERBB4	APH1B EGF PSEN1	3.01e-04	58	32	3	M544
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	PTPN5 FLNA FLNB FLNC EGF	3.11e-04	267	32	5	M10792
Pathway	REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS	APH1B PSEN1	4.47e-04	14	32	2	MM14826
Pathway	REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS	APH1B PSEN1	5.87e-04	16	32	2	M7257
Pathway	PID_SYNDECAN_3_PATHWAY	APH1B PSEN1	6.65e-04	17	32	2	M251
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA FLNC	7.47e-04	18	32	2	MM15123
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA FLNC	7.47e-04	18	32	2	M840
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	APH1B EGF PSEN1	8.33e-04	82	32	3	MM15922
Pathway	WP_FOCAL_ADHESION	FLNA FLNB FLNC EGF	1.02e-03	199	32	4	M39402
Pathway	KEGG_FOCAL_ADHESION	FLNA FLNB FLNC EGF	1.02e-03	199	32	4	M7253
Pathway	REACTOME_SIGNALING_BY_TGFBR3	APH1B PSEN1	1.02e-03	21	32	2	MM17231
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	APH1B PSEN1	1.12e-03	22	32	2	M27210
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	APH1B PSEN1	2.23e-03	31	32	2	M592
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R20 TAS2R30	2.23e-03	31	32	2	MM15691
Pathway	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	APH1B PSEN1	2.37e-03	32	32	2	M571
Pathway	REACTOME_SIGNALING_BY_NOTCH2	APH1B PSEN1	2.52e-03	33	32	2	M604
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	APH1B PSEN1	2.68e-03	34	32	2	MM15025
Pathway	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	FLNA FLNC	2.83e-03	35	32	2	M16801
Pathway	WP_EBOLA_VIRUS_INFECTION_IN_HOST	FLNA FLNB FLNC	3.06e-03	129	32	3	M39693
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R20 TAS2R30	3.16e-03	37	32	2	MM15067
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB FLNC	2.17e-09	3	46	3	11252955
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB FLNC	2.17e-09	3	46	3	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB FLNC	2.17e-09	3	46	3	11153914
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNA FLNB FLNC SPTB	8.08e-09	18	46	4	12119179
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB FLNC	8.65e-09	4	46	3	11739414
Pubmed	Interaction of presenilins with the filamin family of actin-binding proteins.	FLNA FLNB PSEN1	8.65e-09	4	46	3	9437013
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB FLNC	8.65e-09	4	46	3	22802962
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB FLNC	2.16e-08	5	46	3	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB FLNC	2.16e-08	5	46	3	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB FLNC	2.16e-08	5	46	3	17360453
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB FLNC	7.55e-08	7	46	3	16076904
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB FLNC	1.21e-07	8	46	3	17145501
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB FLNC	1.81e-07	9	46	3	11807098
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNA FLNB FLNC	3.55e-07	11	46	3	36579465
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	1.71e-06	2	46	2	17635842
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	1.71e-06	2	46	2	12525170
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	1.71e-06	2	46	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	1.71e-06	2	46	2	33649519
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	1.71e-06	2	46	2	9694715
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	1.71e-06	2	46	2	7689010
Pubmed	Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.	PTPN5 PSEN1	1.71e-06	2	46	2	25093460
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	1.71e-06	2	46	2	21325628
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	1.71e-06	2	46	2	10679933
Pubmed	Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.	PTPN5 PSEN1	1.71e-06	2	46	2	20956308
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	1.71e-06	2	46	2	24469451
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNA FLNB FLNC	3.28e-06	22	46	3	18487259
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	5.13e-06	3	46	2	12704190
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	5.13e-06	3	46	2	28175289
Pubmed	Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin.	APH1B PSEN1	5.13e-06	3	46	2	20382452
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	5.13e-06	3	46	2	11038172
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	5.13e-06	3	46	2	22174152
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	5.13e-06	3	46	2	11102480
Pubmed	Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.	PSEN1 ITGB2	5.13e-06	3	46	2	26214837
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	5.13e-06	3	46	2	17825253
Pubmed	Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution.	FLNA PSEN1	5.13e-06	3	46	2	20847418
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	5.13e-06	3	46	2	9412467
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	5.13e-06	3	46	2	38989458
Pubmed	Reconstitution of gamma-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of gamma-secretase complex.	APH1B PSEN1	1.03e-05	4	46	2	16371134
Pubmed	The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.	FLNA FLNC	1.03e-05	4	46	2	20554076
Pubmed	Expression profiles of two human APH-1 genes and their roles in formation of presenilin complexes.	APH1B PSEN1	1.03e-05	4	46	2	15629423
Pubmed	Gamma-secretase complex assembly within the early secretory pathway.	APH1B PSEN1	1.03e-05	4	46	2	15591316
Pubmed	Epidermal growth factor (EGF) regulates α5β1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A.	FLNA EGF	1.03e-05	4	46	2	23007402
Pubmed	By suppressing the expression of anterior pharynx-defective-1α and -1β and inhibiting the aggregation of β-amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice.	APH1B PSEN1	1.03e-05	4	46	2	26293690
Pubmed	APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes.	APH1B PSEN1	1.71e-05	5	46	2	12471034
Pubmed	Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk.	FLNA ITGB2	1.71e-05	5	46	2	19828450
Pubmed	Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.	APH1B PSEN1	1.71e-05	5	46	2	22140537
Pubmed	Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2.	APH1B PSEN1	1.71e-05	5	46	2	12740439
Pubmed	APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.	APH1B PSEN1	1.71e-05	5	46	2	15634781
Pubmed	Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.	EGF PSEN1	1.71e-05	5	46	2	20208556
Pubmed	Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.	FLNA FLNB FLNC	2.23e-05	41	46	3	18157088
Pubmed	Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity.	APH1B PSEN1	2.56e-05	6	46	2	15474363
Pubmed	Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.	APH1B PSEN1	2.56e-05	6	46	2	14717705
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNA FLNB	2.56e-05	6	46	2	16106752
Pubmed	Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch.	APH1B PSEN1	2.56e-05	6	46	2	12297508
Pubmed	Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.	FLNA FLNC	2.56e-05	6	46	2	9006895
Pubmed	APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity.	APH1B PSEN1	2.56e-05	6	46	2	12763021
Pubmed	ASB2 targets filamins A and B to proteasomal degradation.	FLNA FLNB	2.56e-05	6	46	2	18799729
Pubmed	Specific combinations of presenilins and Aph1s affect the substrate specificity and activity of γ-secretase.	APH1B PSEN1	2.56e-05	6	46	2	27608597
Pubmed	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.	FLNA FLNC	2.56e-05	6	46	2	12679033
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	FLNA FLNB FLNC	3.16e-05	46	46	3	33403043
Pubmed	HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.	FLNA FLNC	3.58e-05	7	46	2	26929074
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FLNA FLNB	4.77e-05	8	46	2	34131310
Pubmed	A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.	APH1B PSEN1	4.77e-05	8	46	2	10206645
Pubmed	Filamin B mutations cause chondrocyte defects in skeletal development.	FLNA FLNB	4.77e-05	8	46	2	17510210
Pubmed	HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity.	FLNA FLNC	4.77e-05	8	46	2	28827800
Pubmed	Purification and characterization of the human gamma-secretase complex.	APH1B PSEN1	4.77e-05	8	46	2	15274632
Pubmed	Comparative mapping of the actin-binding protein 280 genes in human and mouse.	FLNA FLNC	6.12e-05	9	46	2	8088838
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CCR10 FLNA FLNB FLNC CYP4F2	7.33e-05	329	46	5	17474147
Pubmed	Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.	FLNA FLNB	7.65e-05	10	46	2	24436304
Pubmed	The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.	FLNB FLNC	7.65e-05	10	46	2	36357400
Pubmed	Novel progerin-interactive partner proteins hnRNP E1, EGF, Mel 18, and UBC9 interact with lamin A/C.	FLNA EGF	7.65e-05	10	46	2	16248985
Pubmed	Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability.	APH1B PSEN1	7.65e-05	10	46	2	12843241
Pubmed	A genetic contamination in MHC-congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility.	ITGB2 LILRB4	9.34e-05	11	46	2	15761851
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	FLNB FLNC	9.34e-05	11	46	2	19015242
Pubmed	Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?	APH1B PSEN1	9.34e-05	11	46	2	17986144
Pubmed	Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.	COMT ITGB2	9.34e-05	11	46	2	17016617
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R20 TAS2R30	1.12e-04	12	46	2	12379855
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R20 TAS2R30	1.32e-04	13	46	2	15938754
Pubmed	Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.	APH1B PSEN1	1.54e-04	14	46	2	16630834
Pubmed	Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.	FLNA FLNB	2.03e-04	16	46	2	27789627
Pubmed	p75NTR--live or let die.	APH1B PSEN1	2.03e-04	16	46	2	15721744
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PTPN5 TMEM192 CNNM4 FLNA FLNB FLNC EDEM1	2.73e-04	974	46	7	28675297
Pubmed	Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development.	FLNA FLNC	2.88e-04	19	46	2	29374072
Pubmed	A genome-wide assessment of variability in human serum metabolism.	CYP4F2 FADS1	2.88e-04	19	46	2	23281178
Pubmed	A novel family of mammalian taste receptors.	TAS2R20 TAS2R30	3.54e-04	21	46	2	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R20 TAS2R30	3.89e-04	22	46	2	12734386
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	TMEM192 CNNM4 FLNA FLNB FLNC	4.38e-04	484	46	5	31995728
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	TMEM184C FADS1 COMT SNX19 PIGO	5.03e-04	499	46	5	22810586
Pubmed	Receptors for bitter and sweet taste.	TAS2R20 TAS2R30	5.04e-04	25	46	2	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R20 TAS2R30	5.45e-04	26	46	2	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R20 TAS2R30	5.88e-04	27	46	2	12581520
Pubmed	Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.	FLNA PSEN1	5.88e-04	27	46	2	24586749
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R20 TAS2R30	6.33e-04	28	46	2	15744053
Pubmed	Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.	CERS5 FADS1	6.79e-04	29	46	2	38485951
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	TAS2R20 TAS2R30	7.27e-04	30	46	2	17273929
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R20 TAS2R30	7.27e-04	30	46	2	12679530
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	PSEN1 ITGB2	8.28e-04	32	46	2	18842294
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	FLNA FLNB	8.28e-04	32	46	2	27114546
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R20 TAS2R30	9.35e-04	34	46	2	15496549
Pubmed	A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.	FLNA FLNB	9.35e-04	34	46	2	12577067
Interaction	HSPB7 interactions	FLNA FLNB FLNC	1.54e-05	24	41	3	int:HSPB7
Interaction	TSPAN15 interactions	LMBR1 TMEM192 CNNM4 FADS1 SNX19 KRTCAP3	1.88e-05	276	41	6	int:TSPAN15
Interaction	PSEN2 interactions	APH1B FLNA FLNB PSEN1	2.77e-05	86	41	4	int:PSEN2
Interaction	MS4A15 interactions	FADS1 EDEM1 PIGO	6.79e-05	39	41	3	int:MS4A15
Interaction	PSEN1 interactions	APH1B FLNA FLNB FADS1 PSEN1	9.34e-05	227	41	5	int:PSEN1
Cytoband	9p13.1	FAM74A3 FAM74A1	2.56e-04	24	45	2	9p13.1
Cytoband	12p13.2	TAS2R20 TAS2R30	9.05e-04	45	45	2	12p13.2
GeneFamily	Taste 2 receptors	TAS2R20 TAS2R30 TAS2R33 TAS2R36	2.26e-07	39	25	4	1162
GeneFamily	Olfactory receptors, family 2	OR2A25 OR2T10	1.06e-02	113	25	2	149
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 ILDR1 EGF ABCA13 ST14	7.41e-07	172	44	5	bc1b889ac5e07b8324ae5837eca911f9c865e959
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 ILDR1 EGF ABCA13 ST14	7.41e-07	172	44	5	ba70b6110b70afb1870e8dcaf58c507b8c7d918e
ToppCell	CF-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	FLNB FADS1 SMIM3 ST14 LILRB4	1.12e-06	187	44	5	adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCell	ILEUM-non-inflamed-(3)_pDC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB FADS1 SLC18B1 LILRB4	2.01e-05	163	44	4	bc5411702badab39143905aa51676b4bbfad2041
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 ABCA13 LILRB4	2.43e-05	171	44	4	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 ABCA13 LILRB4	2.43e-05	171	44	4	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 ABCA13 LILRB4	2.43e-05	171	44	4	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 ABCA13 LILRB4	2.78e-05	177	44	4	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 ABCA13 LILRB4	2.78e-05	177	44	4	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FLNB SMIM3 ST14 LILRB4	3.17e-05	183	44	4	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.17e-05	183	44	4	6b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.17e-05	183	44	4	f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	FLNB SMIM3 ST14 LILRB4	3.23e-05	184	44	4	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.23e-05	184	44	4	8939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.30e-05	185	44	4	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.37e-05	186	44	4	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	FLNB SLC18B1 ST14 LILRB4	3.44e-05	187	44	4	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.52e-05	188	44	4	d2d2b6c49448da24f457cedcd213f68841834a99
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.52e-05	188	44	4	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.52e-05	188	44	4	ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.59e-05	189	44	4	ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.59e-05	189	44	4	e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.59e-05	189	44	4	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 FLNB ILDR1 ST14	3.67e-05	190	44	4	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.67e-05	190	44	4	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.67e-05	190	44	4	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 FLNB ILDR1 ST14	3.67e-05	190	44	4	d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell	myeloid-pDC\|World / Lineage and Cell class	FLNB SMIM3 ST14 LILRB4	3.67e-05	190	44	4	88c42779ce2f817d28e672d83f3f1158581edf73
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.74e-05	191	44	4	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.74e-05	191	44	4	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.74e-05	191	44	4	297bc79adc5fef211497819b4861b52cd26ac754
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.74e-05	191	44	4	e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.82e-05	192	44	4	61c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.82e-05	192	44	4	e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 FLNB ILDR1 ST14	3.90e-05	193	44	4	536b277d90070c4571c592a3c6323b4bf4819f67
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.90e-05	193	44	4	b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 FLNB ILDR1 ST14	3.90e-05	193	44	4	0499611c21d283321ef6dd24add154dea48da1b7
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR1 EGF ABCA13 ST14	3.90e-05	193	44	4	241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	FLNB FADS1 ST14 LILRB4	3.98e-05	194	44	4	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	severe-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNB SMIM3 ST14 LILRB4	4.30e-05	198	44	4	3c4820a8391088682fb3e47b914f872533bae227
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	FADS1 COMT SMIM3 LILRB4	4.39e-05	199	44	4	2f6074a2fd3323f258be03042f77929640ad0a75
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC-DCs\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMIM3 ITGB2 ST14 LILRB4	4.48e-05	200	44	4	0576e34dc9a6adae5782659511d641781c6a44ed
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMIM3 ITGB2 ST14 LILRB4	4.48e-05	200	44	4	337daee31dd5a277b9ef1dbd7fd6660371636084
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC-DCs-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMIM3 ITGB2 ST14 LILRB4	4.48e-05	200	44	4	b074b30cd7bb893c24cd49af1b2126825c59eef7
ToppCell	Parenchyma_Control_(B.)-Immune-TX-DCs\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SMIM3 ITGB2 ST14 LILRB4	4.48e-05	200	44	4	cae0e62804e41828e9cf74b9e3452c43a12bc87d
ToppCell	(54)_pDC\|World / shred on Cell_type and subtype	FLNB FADS1 ST14 LILRB4	4.74e-05	203	44	4	b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCell	(09)_Ionocytes-(3)_72hpi\|(09)_Ionocytes / shred by cell type and Timepoint	TMEM184C FLNA FADS1	1.75e-04	110	44	3	fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN5 XKR7 EGF	2.55e-04	125	44	3	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC2\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CYP4F2 ITGB2 LILRB4	3.56e-04	140	44	3	c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNC CYP4F2 ABCA13	3.71e-04	142	44	3	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLNC CYP4F2 ABCA13	3.78e-04	143	44	3	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNA ITGB2 AGTRAP	3.94e-04	145	44	3	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	XKR7 CATSPERD ABCA13	4.02e-04	146	44	3	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	USP43 CYP4F2 TAS2R30	4.35e-04	150	44	3	040468880f69b050c7e992749a165280eb6e61ef
ToppCell	facs-Aorta-Heart-24m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 KRTCAP3 LILRB4	4.52e-04	152	44	3	1da25f913b0fb167f66e539aef509ca44893a878
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	APH1B ITGB2 LILRB4	4.52e-04	152	44	3	931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 KRTCAP3 LILRB4	4.52e-04	152	44	3	254f92d9e6c9c6404f3875dd54d655af87854b14
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ABCA13 LILRB4	4.61e-04	153	44	3	cb144b8c487286384b47fdff88ff98fcf0508899
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 ABCA13 LILRB4	4.88e-04	156	44	3	c841faa1695ff577b0774f531adf1343d05dce9e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 ABCA13 LILRB4	4.88e-04	156	44	3	21baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	FLNC OR2A25 ITGB2	4.97e-04	157	44	3	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	facs-Lung-Endomucin-24m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.16e-04	159	44	3	886cbaef39a3517514a3896b6b960d01a3af043d
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNA EDEM1 ST14	5.25e-04	160	44	3	6ed37d1fd0304932319d6b942502404115ff36a7
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 FADS1 LILRB4	5.45e-04	162	44	3	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 ABCA13 LILRB4	5.54e-04	163	44	3	abec4389cd88252449f110fe95416d67424b403a
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMIM3 ITGB2 LILRB4	5.54e-04	163	44	3	aaff80d254131d1f1230bb12b6f43bc061ab5ab3
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMIM3 ITGB2 LILRB4	5.54e-04	163	44	3	8b0f8a2d5b38f3bbff265211a7607acc85fa38b0
ToppCell	droplet-Pancreas-Endocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMIM3 ITGB2 LILRB4	5.54e-04	163	44	3	644c8a8af6a378fced4c70dec9a0de906f8d6e69
ToppCell	droplet-Kidney-nan-24m-Myeloid-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.64e-04	164	44	3	d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	XKR7 TAS2R30 LILRB4	5.64e-04	164	44	3	057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell	droplet-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.64e-04	164	44	3	d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCell	droplet-Kidney-nan-24m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.64e-04	164	44	3	718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA ITGB2 LILRB4	5.74e-04	165	44	3	1d844d19ff9b49dd0f61f0b24799e172076771ef
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA ITGB2 LILRB4	5.74e-04	165	44	3	9a6abd0e6b11860231ce5e845c87b8d66f3ef697
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA ITGB2 LILRB4	5.74e-04	165	44	3	433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 EDEM1 SPTB	5.74e-04	165	44	3	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	facs-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.74e-04	165	44	3	720649f330382ea2a68c64a5344160a048afb8f1
ToppCell	Mild/Remission-B_memory-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FLNA FLNB ITGB2	5.85e-04	166	44	3	03e1a369d8a83b814def07e29cabb023226b4828
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMEM52 PSEN1 ITGB2	5.85e-04	166	44	3	063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCell	mild_COVID-19_(asymptomatic)-Plasmablast\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TMEM52 CCR10 ILDR1	5.85e-04	166	44	3	0cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMEM52 PSEN1 ITGB2	5.85e-04	166	44	3	417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCell	facs-Heart-LA-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 KRTCAP3 LILRB4	5.85e-04	166	44	3	19ec59f0a43d4eb5b4cc7bcd6480ada7f469054b
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMEM52 PSEN1 ITGB2	5.85e-04	166	44	3	f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	5.85e-04	166	44	3	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM52 EDEM1 ST14	5.95e-04	167	44	3	8ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM52 EDEM1 ST14	5.95e-04	167	44	3	a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell	mild_COVID-19_(asymptomatic)-Plasmablast\|World / disease group, cell group and cell class (v2)	TMEM52 CCR10 ILDR1	5.95e-04	167	44	3	f26ae4de4804a3486502e3df37eabf3dfca688f5
ToppCell	B_cells-pDCs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FLNB ST14 LILRB4	6.05e-04	168	44	3	dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.05e-04	168	44	3	3611605114f6b668b44728d6563cd02389e106af
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA13 SPTB LILRB4	6.05e-04	168	44	3	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	(3)_DC_plasmacytoid\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FLNB SMIM3 LILRB4	6.05e-04	168	44	3	8a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 EDEM1 ST14	6.16e-04	169	44	3	e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	f38b52972a6c492ce2fd520a26bb3fc8db23bf85
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	facs-Marrow-Granulocytes-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	ee1969755180df58d32904e2bb4192da9373d03e
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 EDEM1 ST14	6.16e-04	169	44	3	3167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	2d3618f78484bd3508b7bdae3a0d0183cdae5057
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ITGB2 LILRB4	6.16e-04	169	44	3	5320da1d61806b53e0bd96bbdfdb8fd69246681b
Computational	Actin cytoskeleton binding.	FLNA FLNB FLNC	3.35e-05	30	23	3	MODULE_524
Computational	Genes in the cancer module 419.	FLNA FLNB FLNC	4.90e-05	34	23	3	MODULE_419
Drug	Leu-asp-val	EGF PSEN1 ITGB2	6.99e-06	20	43	3	CID000130816
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB FLNC	1.81e-09	3	37	3	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB FLNC	1.81e-09	3	37	3	DOID:0111190 (implicated_via_orthology)
Disease	myopathy (implicated_via_orthology)	FLNA FLNB FLNC	3.02e-05	48	37	3	DOID:423 (implicated_via_orthology)
Disease	Dermatitis	EGF ITGB2	1.82e-04	16	37	2	C0011603
Disease	hypertension (biomarker_via_orthology)	CYP4F2 FADS1 COMT AGTRAP	1.85e-04	227	37	4	DOID:10763 (biomarker_via_orthology)
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	2.58e-04	19	37	2	DOID:2256 (is_implicated_in)
Disease	internet addiction disorder	FLNB COMT	7.88e-04	33	37	2	EFO_0803368
Disease	endometrial cancer (is_implicated_in)	EGF COMT	9.38e-04	36	37	2	DOID:1380 (is_implicated_in)
Disease	Cognition Disorders	PSEN1 COMT	1.05e-03	38	37	2	C0009241

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLLTIPISLWVILQH	TMEM184C	56	Q9NVA4
WGILLIVLLTHLLVS	APH1B	186	Q8WW43
LLLHLAVFLWIIIAI	FAM74A1	91	Q5RGS3
GRAHLVSVIVWLLSL	CCR10	156	P46092
ILLIISSILGSVWLA	CATSPERD	726	Q86XM0
TVLLLLRVLLHWDLL	ABCA13	4666	Q86UQ4
LLLTLQLLHVIWSYL	CERS5	316	Q8N5B7
LTWIHLLVIIGSILS	ATP10D	1251	Q9P241
LSVGLVLVTTLVWHL	PTPN5	151	P54829
RHWEVLIGVLVVSIL	LILRB4	256	Q8NHJ6
LLALLILGIVWVASA	LMBR1	156	Q8WVP7
NLKLILGLVWTLILH	FLNB	106	O75369
VISWIIGIIHSVIQL	OR4F6	146	Q8NGB9
LSLLLHLAVFLWIII	FAM74A3	121	Q4VXF1
NLKLILGLIWTLILH	FLNC	126	Q14315
LHWLTVIFIILGALL	ILDR1	166	Q86SU0
LSLLLHLAVFLWIII	FAM74A7	121	A6NL05
WNITLILLIHIDSSL	OR2T10	41	Q8NGZ9
LHWITRGVVLLLFLA	NPC1L1	841	Q9UHC9
GILLLVIWKALIHLS	ITGB2	716	P05107
LVLLVVLLLLLRHWG	COMT	16	P21964
VVLVMLLLLSLWGAH	EGF	1041	P01133
LILGLIWTLILHYSI	FLNA	136	P21333
LLLLVGASWLLAHVL	CYP4F2	21	P78329
LLHILLLDGAAWLTL	FADS1	136	O60427
VLLRLGLHGVLWLVF	EDEM1	11	Q92611
DRLLLLVIWTHLGGI	RTL8C	156	O15255
LHWVLLALALVNLLL	KRTCAP3	91	Q53RY4
ITLALTSWILGVLLA	OR2A25	141	A4D2G3
TSWILGVLLALVHLV	OR2A25	146	A4D2G3
LAVSRVGLLWVILLH	TAS2R20	51	P59543
LAVSRVGLLWVLLLH	TAS2R30	51	P59541
LVVSRVGLLWVILLH	TAS2R33	51	P0DSN6
LVVSRVGLLWVILLH	TAS2R36	51	P0DTE0
VIHAWLIISSLLLLF	PSEN1	161	P49768
LHIKSQLWLLVLILV	SLC18B1	326	Q6NT16
PLWLHILLITVLLVL	CNNM4	181	Q6P4Q7
VNLKVILLGHWLLTT	AGTRAP	6	Q6RW13
IILGKVILWILHLLL	TMEM192	96	Q8IY95
LSLWTLPDILIIHLK	USP43	576	Q70EL4
LCIWLLQTLVHLLQL	XKR7	176	Q5GH72
SSLWHVGLILLAVLL	TMEM52	51	Q8NDY8
HILDIWVIVLIILAT	SMIM3	16	Q9BZL3
LLVLLGIGFLVWHLQ	ST14	66	Q9Y5Y6
GVVVLILALVLAWLS	TMUB2	41	Q71RG4
GNHRLVLGLIWTIIL	SPTB	141	P11277
AVGVLLGWLLVIHLL	SNX19	31	Q92543
VIHLLVNVWLLCLLS	SNX19	41	Q92543
LLGSFILLLVVQLHW	PIGO	576	Q8TEQ8
ILLLVVQLHWEGQLL	PIGO	581	Q8TEQ8