Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsymporter activity

SLC6A8 MFSD2A SLC16A13 SLC4A8 SLC20A2 SLC39A4 SLC2A12

4.15e-06150877GO:0015293
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A8 MFSD2A SLC16A13 SLC4A8 SLC25A40 SLC39A4 GRIK4 SLC38A8 SLC35B1

5.26e-06293879GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC16A13 SLC4A8 SLC20A2 SLC39A4 SLC2A12 SLC35B1

5.71e-06296879GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC16A13 SLC4A8 SLC20A2 SLC39A4 ATP2A2 SLC2A12 SLC35B1

4.25e-054778710GO:0022804
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC16A13 SLC4A8 SLC25A40 SLC20A2 SLC39A4 GRIK4 CLDN4 ATP2A2 SLC2A12 SLC38A8 RHCE RHD SLC35B1

4.43e-0511808716GO:0022857
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC4A8 SLC20A2 GRIK4

1.03e-04171876GO:0015081
GeneOntologyMolecularFunctiontransporter activity

SLC6A8 SLC9B1 MFSD2A SLC16A13 SLC4A8 SLC25A40 SLC20A2 SLC39A4 GRIK4 CLDN4 ATP2A2 SLC2A12 SLC38A8 RHCE RHD SLC35B1

1.26e-0412898716GO:0005215
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP155 NPAP1 NUP88

1.71e-0425873GO:0017056
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A8 MFSD2A SLC4A8 SLC20A2 SLC39A4

1.73e-04119875GO:0015294
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC4A8 SLC20A2 SLC39A4 ATP2A2

3.44e-04301877GO:0022853
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC4A8 SLC20A2 SLC39A4 GRIK4 ATP2A2 RHCE RHD

3.94e-046278710GO:0022890
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A8 MFSD2A SLC4A8 SLC20A2

4.33e-0481874GO:0015370
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC4A8 SLC20A2 SLC39A4 GRIK4 CLDN4 ATP2A2 RHCE RHD

4.44e-047588711GO:0015318
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPFFR2 UNC5A OR6V1 FLT4 HMCN2 PTPRG PTPRO OR6C2 FCRLB IL17RC GRIK4 CLDN4 PTGER1 PLXNA2 CCKBR

6.96e-0413538715GO:0004888
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A8 SLC9B1 MFSD2A SLC4A8 SLC20A2 SLC39A4 GRIK4 ATP2A2

9.53e-04465878GO:0046873
GeneOntologyMolecularFunctionserine-type exopeptidase activity

DPP7 CPVL

1.20e-0312872GO:0070008
GeneOntologyMolecularFunctionammonium channel activity

RHCE RHD

1.20e-0312872GO:0008519
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A8 SLC39A4

1.42e-0313872GO:0140410
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A8 MFSD2A SLC16A13 GRIK4 SLC38A8

2.12e-03207875GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A8 MFSD2A SLC16A13 GRIK4 SLC38A8

2.16e-03208875GO:0005342
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRG PTPRO

2.45e-0317872GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRG PTPRO

2.45e-0317872GO:0019198
GeneOntologyBiologicalProcessorganic anion transport

UGT1A3 SLC6A8 ACE2 MFSD2A SLC16A13 SLC4A8 ARL6IP1 SLC25A40 CLTRN SLC39A4 SLC38A8 SLC35B1

1.89e-065158812GO:0015711
GeneOntologyBiologicalProcesspositive regulation of proline import across plasma membrane

ACE2 CLTRN

1.80e-052882GO:1902836
GeneOntologyBiologicalProcessregulation of proline import across plasma membrane

ACE2 CLTRN

1.80e-052882GO:1902834
GeneOntologyBiologicalProcessregulation of L-proline import across plasma membrane

ACE2 CLTRN

1.80e-052882GO:1905735
GeneOntologyBiologicalProcesspositive regulation of L-proline import across plasma membrane

ACE2 CLTRN

1.80e-052882GO:1905737
GeneOntologyBiologicalProcessregulation of proline transport

ACE2 CLTRN

5.38e-053882GO:0070881
GeneOntologyBiologicalProcessregulation of amino acid transmembrane transport

ACE2 ARL6IP1 CLTRN

1.09e-0422883GO:1903789
GeneOntologyBiologicalProcessregulation of amino acid import across plasma membrane

ACE2 ARL6IP1 CLTRN

1.09e-0422883GO:0010958
GeneOntologyBiologicalProcessproline import across plasma membrane

ACE2 CLTRN

1.78e-045882GO:1905647
GeneOntologyBiologicalProcessL-proline import across plasma membrane

ACE2 CLTRN

1.78e-045882GO:1904271
GeneOntologyBiologicalProcessL-proline transmembrane transport

ACE2 CLTRN

1.78e-045882GO:1904555
GeneOntologyBiologicalProcessammonium homeostasis

RHCE RHD

2.67e-046882GO:0097272
GeneOntologyBiologicalProcesscarboxylic acid transport

UGT1A3 SLC6A8 ACE2 MFSD2A SLC16A13 ARL6IP1 CLTRN SLC38A8

3.66e-04410888GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

UGT1A3 SLC6A8 ACE2 MFSD2A SLC16A13 ARL6IP1 CLTRN SLC38A8

3.78e-04412888GO:0015849
DomainCollectrin_dom

ACE2 CLTRN

2.10e-052862IPR031588
DomainCollectrin

ACE2 CLTRN

2.10e-052862PF16959
DomainPeptidase_M2

ACE2 CLTRN

6.27e-053862IPR001548
DomainAmmonium_transpt

RHCE RHD

2.08e-045862IPR001905
DomainAmmonium_transp

RHCE RHD

2.08e-045862PF00909
DomainNH4_transpt_AmtB-like_dom

RHCE RHD

2.08e-045862IPR024041
DomainRhesusRHD

RHCE RHD

2.08e-045862IPR002229
DomainIg-like_fold

UNC5A BTN2A2 ANOS1 FLT4 MXRA5 HMCN2 PTPRG PTPRO ICAM4 FCRLB PLXNA2

3.86e-047068611IPR013783
Domain-

RHCE RHD

4.34e-0478621.10.3430.10
DomainAmmonium/urea_transptr

RHCE RHD

4.34e-047862IPR029020
Domain-

UNC5A BTN2A2 ANOS1 FLT4 MXRA5 PTPRG PTPRO ICAM4 FCRLB PLXNA2

9.26e-0466386102.60.40.10
DomainAdipoR/HlyIII-related

PAQR4 MMD2

1.12e-0311862IPR004254
DomainHlyIII

PAQR4 MMD2

1.12e-0311862PF03006
DomainRCC1

RCBTB1 HERC1

3.77e-0320862PF00415
DomainRCC1_1

RCBTB1 HERC1

4.16e-0321862PS00625
DomainRCC1_2

RCBTB1 HERC1

4.16e-0321862PS00626
DomainRCC1_3

RCBTB1 HERC1

4.16e-0321862PS50012
DomainReg_chr_condens

RCBTB1 HERC1

4.56e-0322862IPR000408
Domain-

RCBTB1 HERC1

4.56e-03228622.130.10.30
DomainRCC1/BLIP-II

RCBTB1 HERC1

4.98e-0323862IPR009091
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

SLC6A8 MFSD2A ARL6IP1 SLC20A2 TMEM70 NUP88 RHBDD2 SLC39A4 ATP2A2 CCKBR SLC35B1

1.92e-06697901128298427
Pubmed

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.

RHCE RHD

6.62e-0629028188244
Pubmed

E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.

RHCE RHD

6.62e-06290211724987
Pubmed

DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.

RHCE RHD

6.62e-06290217900276
Pubmed

RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.

RHCE RHD

6.62e-06290232697929
Pubmed

The Rh blood group system: a review.

RHCE RHD

6.62e-06290210627438
Pubmed

Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.

RHCE RHD

6.62e-06290237823181
Pubmed

Sequence diversity of the Rh blood group system in Basques.

RHCE RHD

6.62e-06290230089826
Pubmed

Review: the molecular basis of the Rh blood group phenotypes.

RHCE RHD

6.62e-06290215373666
Pubmed

Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.

RHCE RHD

6.62e-06290226579938
Pubmed

Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.

RHCE RHD

6.62e-06290234968422
Pubmed

Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.

RHCE RHD

6.62e-06290229193104
Pubmed

Regarding the size of Rh proteins.

RHCE RHD

6.62e-0629021898705
Pubmed

PCR screening for common weak D types shows different distributions in three Central European populations.

RHCE RHD

6.62e-06290211161244
Pubmed

RH diversity in Mali: characterization of a new haplotype RHD*DIVa/RHCE*ceTI(D2).

RHCE RHD

6.62e-06290225857637
Pubmed

The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL.

RHCE RHD

6.62e-06290222738288
Pubmed

Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction.

ACE2 CLTRN

6.62e-06290224048198
Pubmed

Multiple Rh messenger RNA isoforms are produced by alternative splicing.

RHCE RHD

6.62e-0629021379850
Pubmed

RHCE variants inherited with altered RHD alleles in Brazilian blood donors.

RHCE RHD

6.62e-06290227111588
Pubmed

Characterization of the mouse Rh blood group gene.

RHCE RHD

6.62e-06290210329015
Pubmed

Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.

RHCE RHD

6.62e-0629028822955
Pubmed

Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.

RHCE RHD

6.62e-0629028808597
Pubmed

Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.

RHCE RHD

6.62e-06290212201845
Pubmed

Variant RH alleles and Rh immunisation in patients with sickle cell disease.

RHCE RHD

6.62e-06290224960646
Pubmed

RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.

RHCE RHD

6.62e-06290223772606
Pubmed

Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.

RHCE RHD

6.62e-06290230418133
Pubmed

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.

RHCE RHD

6.62e-06290223550903
Pubmed

Molecular cloning and primary structure of the human blood group RhD polypeptide.

RHCE RHD

6.62e-0629021438298
Pubmed

Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.

RHCE RHD

6.62e-0629023135863
Pubmed

Molecular background of D(C)(e) haplotypes within the white population.

RHCE RHD

6.62e-06290212084172
Pubmed

The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.

RHCE RHD

6.62e-06290210924335
Pubmed

Sequences and evolution of mammalian RH gene transcripts and proteins.

RHCE RHD

6.62e-0629029811965
Pubmed

A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.

RHCE RHD

6.62e-06290212857961
Pubmed

Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.

RHCE RHD

6.62e-06290220233350
Pubmed

Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.

RHCE RHD

6.62e-06290212393640
Pubmed

Molecular genetic basis of the human Rhesus blood group system.

RHCE RHD

6.62e-0629028220426
Pubmed

A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.

RHCE RHD

6.62e-0629028900235
Pubmed

RHD*weak partial 4.0 is associated with an altered RHCE*ce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.

RHCE RHD

6.62e-06290223742316
Pubmed

Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.

RHCE RHD

6.62e-0629027916743
Pubmed

A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.

RHCE RHD

6.62e-06290224033223
Pubmed

RHD*DOL1 and RHD*DOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.

RHCE RHD

6.62e-06290222690701
Pubmed

No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.

RHCE RHD

6.62e-06290226872772
Pubmed

Collectrin and ACE2 in renal and intestinal amino acid transport.

ACE2 CLTRN

6.62e-06290221814048
Pubmed

RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa.

RHCE RHD

6.62e-06290222804620
Pubmed

Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.

RHCE RHD

6.62e-0629027789951
Pubmed

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.

TSKU FLT4 PTPRG ARL6IP1 CLDN4 MAP3K12 CEP164

1.53e-0530690718973680
Pubmed

Generation and characterisation of Rhd and Rhag null mice.

RHCE RHD

1.98e-05390219807729
Pubmed

Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures.

RHCE RHD

1.98e-05390216584906
Pubmed

Evolutionary history of the Rh blood group-related genes in vertebrates.

RHCE RHD

1.98e-05390210970100
Pubmed

Conserved evolution of the Rh50 gene compared to its homologous Rh blood group gene.

RHCE RHD

1.98e-0539029705835
Pubmed

Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.

ACE2 CLTRN

1.98e-05390219185582
Pubmed

Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B0AT1 Is Required for Optimal Preimplantation Embryo Development in Mice.

ACE2 CLTRN

1.98e-05390236611813
Pubmed

Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3.

ACE2 CLTRN

1.98e-05390219478081
Pubmed

The members of the RH gene family (RH50 and RH30) followed different evolutionary pathways.

RHCE RHD

1.98e-0539029929383
Pubmed

Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.

RHCE RHD

1.98e-0539023146980
Pubmed

Entire sequence of a mouse chromosomal segment containing the gene Rhced and a comparative analysis of the homologous human sequence.

RHCE RHD

3.96e-05490212459264
Pubmed

HLA-DRB1 molecules and the presentation of anchor peptides from RhD, RhCE, and KEL proteins.

RHCE RHD

3.96e-05490233675036
Pubmed

Association between ABO, Rhesus blood group systems and haemoglobin genotype among confirmed HIV/AIDS-TB co-infected patients in Enugu Urban, Nigeria.

RHCE RHD

3.96e-05490216722361
Pubmed

Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.

UNC5A ALDH1A1 PLXNA2

6.47e-053090332562661
Pubmed

RHCE represents the ancestral RH position, while RHD is the duplicated gene.

RHCE RHD

6.59e-05590211902138
Pubmed

Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors.

ACE2 CLTRN

6.59e-05590225534429
Pubmed

Evolutionary conservation and diversification of Rh family genes and proteins.

RHCE RHD

6.59e-05590216227429
Pubmed

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.

ACE2 CLTRN

6.59e-05590222837003
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

DPP7 TBRG4 USP24 TRAPPC8 DOCK6

1.17e-0418390531932471
Pubmed

Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.

PTPRG PTPRO

1.38e-04790215978577
Pubmed

Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.

PTPRG PTPRO

1.38e-0479027804149
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

SLC6A8 TBRG4 NUP155 SLC20A2 RHBDD2 SDF4 TRAPPC8 ATP2A2 CPVL NNT

1.78e-04952901038569033
Pubmed

Complementary expression patterns of retinoid acid-synthesizing and -metabolizing enzymes in pre-natal mouse inner ear structures.

ALDH1A1 DCT

1.84e-04890215161092
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

TSKU ACE2 MFSD2A CLTRN IL17D GPC6 PLXNA2

1.97e-0446090720562862
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

ACE2 SLC4A8 GRIK4 SLC2A12 SLC35B1

2.32e-0421290519521566
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TAOK2 TSKU ACE2 ABHD15 MFSD2A CLTRN IL17RC GPC6 CPVL PLXNA2

2.34e-04985901012975309
Pubmed

[Genetic predisposition to development of toxic liver cirrhosis caused by alcohol].

RHCE RHD

3.59e-041190211436564
Pubmed

PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif.

PAQR4 MMD2

3.59e-041190216044242
Pubmed

TBL2, a novel transducin family member in the WBS deletion: characterization of the complete sequence, genomic structure, transcriptional variants and the mouse ortholog.

ZAN CLDN4

3.59e-041190210575226
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

ART4 SLC20A2 MANEAL TET1 USP24 HERC1 GPC6 VWA5B1 PLXNA2 RHCE RHD

3.63e-041242901130973865
Pubmed

A flexible array format for large-scale, rapid blood group DNA typing.

ART4 ICAM4

4.30e-041290215847654
Pubmed

The mouse Rhl1 and Rhag genes: sequence, organization, expression, and chromosomal mapping.

RHCE RHD

4.30e-041290210495887
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TAOK2 NCAPD3 TBRG4 NUP155 ARL6IP1 TET1 DOCK6

4.56e-0452990714621295
Pubmed

Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.

SEC62 ATP2A2

5.07e-041390222375059
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

MED24 TBRG4 NUP155 SEC62 NUP88 CPVL NNT

6.38e-0456090735241646
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

SLC6A8 ACE2 SLC4A8 PTPRG SLC20A2 PLXNA2 ADD2

7.00e-0456990730639242
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

NUP155 ARL6IP1 HERC1 TRAPPC8 ATP2A2

7.09e-0427190525737280
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TAOK2 MED24 NCAPD3 TBRG4 NUP155 SEC62 USP24 NUP88 ATP2A2

7.52e-0494290931073040
Pubmed

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

USP24 DOCK6

9.86e-041890223726366
Pubmed

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

ACE2 PTGER1

1.10e-031990221052031
Pubmed

Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function.

PLIN1 ATP2A2

1.35e-032190227185876
Pubmed

Large-scale screen for genes involved in gonad development.

MED24 TBRG4 NUP88

1.47e-038690311044607
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

ARL6IP1 USP24

1.48e-032290237225996
Pubmed

Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver.

ICAM4 ADAM8

1.62e-032390228358362
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

TSKU MED24 NCAPD3 CLTRN TMEM70 RHBDD2 SDF4 HERC1 DOCK6

1.72e-03106190933845483
Pubmed

An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity.

ATP2A2 CPVL

1.91e-032590237589075
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

NUP155 NUP88

1.91e-032590210601273
Pubmed

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

NPFFR2 PTGER1 CCKBR

1.95e-039590316754659
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

TAOK2 MED24 NCAPD3 NUP88 SRCAP

1.96e-0334190532971831
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

NUP155 NUP88

2.07e-032690212228227
Pubmed

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

NUP155 NUP88

2.40e-032890229653964
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

USP24 RHBDD2 ATP2A2 CPVL

2.48e-0321790430619736
Pubmed

Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.

RHCE RHD

2.57e-032990216966370
Cytoband12p13-p12

ART4 PTPRO

2.22e-05489212p13-p12
Cytoband13q32

GPC6 DCT

2.86e-041389213q32
CytobandXp22

ACE2 CLTRN

1.08e-0325892Xp22
CytobandEnsembl 112 genes in cytogenetic band chr12p12

ART4 PTPRO DNAI7

1.41e-03113893chr12p12
CytobandEnsembl 112 genes in cytogenetic band chrXp22

ACE2 ANOS1 MXRA5 CLTRN

1.46e-03250894chrXp22
Cytoband16p12.3

DNAH3 COQ7

2.00e-033489216p12.3
Cytoband4q24

SLC9B1 TBCK

2.00e-03348924q24
GeneFamilySolute carriers

SLC6A8 SLC9B1 SLC16A13 SLC4A8 SLC25A40 SLC20A2 SLC39A4 SLC2A12 SLC38A8 SLC35B1

1.81e-063956710752
GeneFamilyGlycosyltransferase family 6|Blood group antigens

ART4 ICAM4 RHCE RHD

1.04e-0537674454
GeneFamilyProgestin and adipoQ receptor family

PAQR4 MMD2

7.28e-0411672930
GeneFamilyImmunoglobulin like domain containing

FLT4 MXRA5 HMCN2 ICAM4 FCRLB

7.44e-04193675594
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRG PTPRO

2.71e-0321672813
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

UNC5A FLT4 MXRA5 HMCN2

3.00e-03161674593
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

TAOK2 MAP3K12

3.54e-0324672654
GeneFamilyNucleoporins

NUP155 NUP88

6.25e-03326721051
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_100

MMD2 ALDH1A1 GPC6 DCT MMD2

1.35e-0576855gudmap_developingGonad_e12.5_epididymis_100
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500

ACE2 TET1 DZIP3 MMD2 ALDH1A1 HERC1 GPC6 DCT MMD2

3.37e-05403859gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_200

TET1 MMD2 ALDH1A1 GPC6 DCT MMD2

4.31e-05159856gudmap_developingGonad_e12.5_epididymis_200
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_100

MMD2 ALDH1A1 MMD2

9.02e-0522853gudmap_developingGonad_e12.5_epididymis_k3_100
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC6A8 ART4 SEC62 HERC1 RHCE ADD2 RHD

1.15e-071899071900e574870fc647bfa11c732a72f3d38aab717c
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC6A8 ART4 HERC1 RHCE ADD2 RHD

2.08e-06185906e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellImmune-enucleated_erythrocyte|World / Lineage, Cell type, age group and donor

SLC6A8 ART4 SEC62 RHCE ADD2 RHD

2.15e-06186906f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFSD2A MXRA5 CLDN4 PTGER1 CPVL VWA5B1

2.82e-061959063d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

SLC6A8 ARL6IP1 ART4 SEC62 RHCE ADD2

2.91e-06196906092caba6726d1acd409a8be335100764d0724e64
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

SLC6A8 ICAM4 ALDH1A1 RHCE ADD2 RHD

2.99e-06197906604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 HERC1 ADAM8 RHD

2.07e-05164905f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP7 NCAPD3 USP24 TM6SF1 CPVL

2.13e-0516590560b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 PTPRO ALDH1A1 ADD2 RHD

2.20e-051669058d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 PTPRO ALDH1A1 ADD2 RHD

2.20e-05166905f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 PTPRO ALDH1A1 ADD2 RHD

2.20e-05166905a5074c96c6561273029aceb93402a7e038140f50
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT4 ART4 CLTRN PLIN1 DOCK6

2.68e-0517390585083b9ce20351dd69aa2327ad087b848b4307ff
ToppCelldroplet-Marrow-nan-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ICAM4 ALDH1A1 ADD2 RHD

2.91e-05176905f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTN2A2 ANOS1 CLDN4 ALDH1A1 GPC6

2.99e-05177905b7fee75de7e96924af488a5baa2334711889ae7c
ToppCelldroplet-Marrow-nan-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ICAM4 ALDH1A1 ADD2 RHD

3.07e-05178905b4e15c176875cd226854a0019495309d02730c42
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ICAM4 ALDH1A1 ADD2 RHD

3.15e-05179905f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ICAM4 ALDH1A1 ADD2 RHD

3.15e-051799057e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ICAM4 ALDH1A1 ADD2 RHD

3.15e-0517990501e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A8 ART4 RHCE ADD2 RHD

3.50e-05183905b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A8 ART4 RHCE ADD2 RHD

3.50e-051839051db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A8 ART4 RHCE ADD2 RHD

3.50e-051839051d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCellwk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC6A8 ART4 ICAM4 RHCE ADD2

3.59e-05184905238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC6A8 ART4 SEC62 RHCE RHD

3.69e-05185905c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLC6A8 ART4 SEC62 RHCE ADD2

3.69e-05185905e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellwk_08-11-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ART4 ICAM4 CPVL RHCE ADD2

3.88e-05187905c0965293f08d3e49000871777a5b26d81a4af203
ToppCelldroplet-Marrow-BM-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 ICAM4 ALDH1A1 ADD2 RHD

3.98e-05188905f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 ICAM4 ALDH1A1 ADD2 RHD

4.08e-0518990516dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 ICAM4 ALDH1A1 ADD2 RHD

4.08e-051899053ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|World / Lineage, cell class and subclass

SLC6A8 ART4 RHCE ADD2 RHD

4.08e-05189905826457adac7477102f86aceb97a8b77929b3e6f9
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|World / Lineage, cell class and subclass

SLC6A8 ART4 RHCE ADD2 RHD

4.19e-051909056c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC25A40 SLC20A2 TBCK ZSWIM1 ADAM8

4.19e-051909053f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 ARL6IP1 NPAP1 PTGER1 CPVL

4.40e-051929059e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 ARL6IP1 NPAP1 PTGER1 CPVL

4.40e-051929053d777d07878269b87ec7e1f06489cae7c989d633
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC25A40 SLC20A2 TBCK ZSWIM1 ADAM8

4.40e-05192905c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 ARL6IP1 NPAP1 PTGER1 CPVL

4.51e-05193905371f4c98a599923fbe8382530b3eab05d873665a
ToppCellsevere_influenza-RBC|severe_influenza / disease group, cell group and cell class (v2)

SLC6A8 ART4 RHCE ADD2 RHD

4.51e-05193905ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFSD2A MXRA5 PTGER1 CPVL VWA5B1

4.62e-051949054579b4a44f7c731553a284843c296866027d7c0e
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

SLC6A8 ART4 SEC62 RHCE RHD

4.62e-05194905f0ababe8daa57f6827a3e2e72c884d9e8b2687a3
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-mid_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC6A8 ART4 SEC62 RHCE ADD2

4.74e-051959054759018a7c016cb2e3df5696f1e5f912c7c9ee17
ToppCell15-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

ART4 ICAM4 RHCE ADD2 RHD

4.85e-05196905511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCell15-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

ART4 ICAM4 RHCE ADD2 RHD

4.85e-05196905bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCell21-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

ART4 ICAM4 RHCE ADD2 RHD

4.97e-051979059f8eb6305ade0654bbcd8f19963be0b64af083de
ToppCell21-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

ART4 ICAM4 RHCE ADD2 RHD

4.97e-051979054710b55806a618076a954190f519e49c55d300d3
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAOK2 SLC9B1 MFSD2A TBRG4 ADAM8

5.22e-051999056dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A8 ACE2 SMLR1 SLC39A4 CLDN4

5.22e-05199905914f66e2b4af323d09fa2340a39cf8051d00a422
ToppCellInfluenza-Influenza_Severe-Others-RBC|Influenza_Severe / Disease, condition lineage and cell class

SLC6A8 ART4 SEC62 RHCE RHD

5.22e-05199905da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MFSD2A FLT4 PTPRG DOCK6 PLXNA2

5.22e-05199905463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC6A8 ART4 RHCE ADD2 RHD

5.34e-05200905b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC6A8 ART4 RHCE ADD2 RHD

5.34e-052009059ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Unfolded_protein_responsible_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

ACE2 MFSD2A SMLR1 CLDN4 RHCE

5.34e-0520090512078bc25be67180c0f4b37fef921cdcd1003576
ToppCellLung_Parenchyma-Severe-Hematopoietic|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC6A8 ART4 RHCE ADD2 RHD

5.34e-05200905fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A8 ACE2 SMLR1 SLC39A4 CLDN4

5.34e-052009053e13c9a4ba99a7dfbf738b0fb63fb54b4dee5897
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC6A8 ART4 RHCE ADD2 RHD

5.34e-05200905199165be1aef8497af71b74690a11de18fbe073c
ToppCell18-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

ANOS1 ZDHHC12 ICAM4 CLDN4 SRCAP

5.34e-052009053c231d0a5809eab0acd6d0a77d54c49ac3eaaff3
ToppCellParenchyma_COVID-19-Stromal-TX-Erythrocytes|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SLC6A8 ART4 RHCE ADD2 RHD

5.34e-05200905a9edac2f5e009662df452ec032a80e855cdac28f
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A8 ACE2 SMLR1 SLC39A4 CLDN4

5.34e-0520090573bfdf068a8ecbefc1e6afe9686df73658ee042f
ToppCellEpithelial-D_(Clara-Club_cells)|World / shred on cell class and cell subclass (v4)

ACE2 MANEAL CLDN4 ALDH1A1

6.84e-0510890493036a6a29fb2a0a5fd1ec35a1acff270d8fead9
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

HMCN2 ART4 DNAI7 CYP4F11

6.84e-05108904c64d56b3be22ce25258e342bc68f37bb8568dead
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANOS1 SLC4A8 HMCN2 PLIN1

1.32e-041289042cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

MFSD2A HMCN2 ART4 CLDN4

3.10e-04160904731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBCK ICAM4 ADD2 RHD

3.10e-041609049f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

MFSD2A HMCN2 ART4 CLDN4

3.10e-04160904cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 ARL6IP1 NPAP1 PTGER1

3.10e-041609047064af50fc10e3ea03badf415306222b74db0f95
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBCK ICAM4 ADD2 RHD

3.10e-041609043b3b99305558f5b49d050fb9b249007630ea9085
ToppCellfacs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 ADD2 RHD

3.18e-0416190479a4a81963c92ade5b6910816a440dc3c233ead2
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANOS1 ICAM4 CLDN4 GPC6

3.18e-041619041e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellfacs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 ADD2 RHD

3.18e-041619041ce40a6d0f0b9870e7ddb3d607668adcbd3dd1d3
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

BTN2A2 ART4 SLC20A2 RHCE

3.33e-04163904e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

BTN2A2 ART4 SLC20A2 RHCE

3.33e-0416390431b60e065bac4ad380247964e7574f210106ebae
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A FLT4 ART4 TM6SF1

3.41e-04164904a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A FLT4 ART4 TM6SF1

3.41e-041649041a1795969673232191425dde84ab24ee6a98143f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A FLT4 ART4 TM6SF1

3.41e-041649048f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC12 SLC4A8 PTPRO IL17D

3.41e-041649040853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_OR1J1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPFFR2 GPC6 CPVL PLXNA2

3.49e-041659041f88f6939f88b80a0c98b4eef3684ba03c64ff7c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BTN2A2 FCRLB TM6SF1 CPVL

3.57e-0416690463dc58864268b4e7779e4c45155022556fc634f9
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC16A13 TRAPPC8 ADAM8 PLXNA2

3.57e-041669043b67064a5149e72f895344d938c64b8ff65247f5
ToppCellfacs-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 ADD2 RHD

3.65e-0416790416bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCellfacs-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 ADD2 RHD

3.65e-04167904515988c7035c550a2f072430d9d7027869593d17
ToppCellfacs-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ALDH1A1 ADD2 RHD

3.65e-04167904f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCellBAL-Control-cDC_6|Control / Compartment, Disease Groups and Clusters

TSKU NCAPD3 DOCK6 ADD2

3.73e-0416890465ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A8 ART4 RHCE RHD

3.73e-04168904360cd756067c8cfb6a78301674758eb5fac52c23
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A8 ART4 RHCE RHD

3.73e-04168904d791116040a9d3ea0485d68c974340116073986b
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HMCN2 ICAM4 FCRLB

3.85e-0470903e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HMCN2 ICAM4 FCRLB

3.85e-047090327e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HMCN2 ICAM4 FCRLB

3.85e-0470903b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MXRA5 PAQR4 DNAI7 SLC38A8

3.90e-04170904f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC12 SLC4A8 RHBDD2 ADAM8

3.99e-04171904ac37c80c832504986c7a201d84f4b6aff5e5f323
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC39A4 IL17RC ALDH1A1

3.99e-04171904e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC12 SLC4A8 RHBDD2 ADAM8

3.99e-04171904b6502a81df4f25660f3ae4b7443a1d999df2d32b
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC39A4 IL17RC ALDH1A1

3.99e-04171904b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCellCOVID-19-lung-RBC|lung / Disease (COVID-19 only), tissue and cell type

ART4 RHCE ADD2 RHD

3.99e-041719040e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 HERC1 ADD2 RHD

4.08e-041729046004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 HERC1 ADD2 RHD

4.08e-0417290431c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 ALDH1A1 ADD2 RHD

4.17e-04173904a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNAH3 SEC62 VWA5B1

4.18e-0472903e3f4d1df43cc41b0424f27485a00ddca9e905f95
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

ACE2 SLC39A4 ALDH1A1 SLC38A8

4.26e-04174904ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell18-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

SLC6A8 RHCE ADD2 RHD

4.35e-041759047130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ART4 HERC1 RHCE RHD

4.35e-041759044c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCell18-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

SLC6A8 RHCE ADD2 RHD

4.35e-04175904cc476b4244442418b8f21721a82a36209b556b36
ToppCellwk_15-18-Hematologic-Meg-ery-Primitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ART4 ICAM4 RHCE ADD2

4.45e-04176904664a7d15563428d0ae156d97aa88415fd0a0506a
ComputationalNeighborhood of TAL1

ICAM4 RHCE ADD2 RHD

3.04e-0473484GNF2_TAL1
ComputationalNeighborhood of SPTB

SLC6A8 ICAM4 RHCE RHD

3.20e-0474484GNF2_SPTB
ComputationalNeighborhood of ANK1

SLC6A8 ICAM4 RHCE RHD

3.20e-0474484GNF2_ANK1
DrugClebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A

TAOK2 SLC6A8 ICAM4 SRCAP DOCK6 ADAM8 ATP2A2 NNT

9.58e-071998785412_UP
DiseaseAnemia, Hemolytic, Congenital

RHCE RHD

8.79e-062882C0002881
DiseaseRh Deficiency Syndrome

RHCE RHD

2.63e-053882C0272052
DiseaseRh-Null, Regulator Type

RHCE RHD

2.63e-053882C1849387
Diseasepancreatic ductal carcinoma (is_marker_for)

ACE2 CLDN4 ADAM8 CCKBR

3.38e-0561884DOID:3587 (is_marker_for)
DiseaseMammary Ductal Carcinoma

CLDN4 PTGER1

4.75e-0411882C0021367
DiseaseInvasive Ductal Breast Carcinoma

CLDN4 PTGER1

4.75e-0411882C1134719
Diseasewhole-brain volume, Alzheimer's disease biomarker measurement

ABHD15 ADD2

7.82e-0414882EFO_0005089, EFO_0006514
DiseaseSchizophrenia

UGT1A3 RCBTB1 TET1 SDF4 GRIK4 ALDH1A1 ATP2A2 PLXNA2 RHD

1.28e-03883889C0036341
Diseaselevel of Sphingomyelin (d34:1) in blood serum

NPFFR2 USP24

1.30e-0318882OBA_2045175
Diseaseresponse to methotrexate, neurotoxicity

GPC6 DCT

1.45e-0319882EFO_0011057, GO_0031427
Diseaseunipolar depression, memory performance, cognitive function measurement

TET1 TRAPPC8

1.61e-0320882EFO_0003761, EFO_0004874, EFO_0008354
DiseaseAutosomal Recessive Primary Microcephaly

MFSD2A NCAPD3

1.95e-0322882C3711387
DiseaseRespiratory Hypersensitivity

SLC39A4 CLDN4

1.95e-0322882C0035228
Diseaselevel of Sphingomyelin (d40:2) in blood serum

NPFFR2 NUP88

2.14e-0323882OBA_2045181
Diseaseairway responsiveness measurement

USP24 DZIP3

2.33e-0324882EFO_0006897
Diseaseneuropsychological test

NCAPD3 MANEAL GRIK4 CPVL

2.90e-03197884EFO_0003926

Protein segments in the cluster

PeptideGeneStartEntry
APGRMEWIIPLIVVS

PTPRG

731

P23470
MATGLQVPLPWLATG

UGT1A3

1

P35503
VAMASRWGPLIGLAP

SDF4

6

Q9BRK5
FPLVMLIWKIGPALS

ALDH1A1

171

P00352
RAWFPPAIMGVVSLV

ARL6IP1

41

Q15041
LWLLGAMMLPAIAPS

ADAM8

6

P78325
VATWLLSGLLMVPYP

CCKBR

176

P32239
MPPWGAALALILAVL

ABHD15

1

Q6UXT9
MVDVGKWPIFTLLSP

RCBTB1

1

Q8NDN9
MPITLLDNIIAGWPF

NPFFR2

201

Q9Y5X5
CWVAGLMIIVPPLSL

OR6C2

146

Q9NZP2
SIGLGPMPWLVLSEI

SLC2A12

476

Q8TD20
MVPGVPGAVLTLCLW

ANOS1

1

P23352
PALVILSMPNTEGIW

MMD2

196

Q8IY49
TVWVLVGTVGMPHLP

NUDT18

201

Q6ZVK8
AWVSLRPGPMALSSV

HMCN2

4831

Q8NDA2
AVREGMSWIVPVPLL

HERC1

4701

Q15751
WKVIVSLVLLMPGPC

CPVL

6

Q9H3G5
LSVVWVLLAPPAAGM

PLXNA2

21

O75051
SPMLVLVALAVGGWS

PTGER1

311

P34995
MLVAGFLLALPPSWA

IL17D

1

Q8TAD2
APLMTGIAWALPAPV

DZIP3

1001

Q86Y13
MGVFPPISRAWLTID

NUP155

106

O75694
GFLVLVPMTMPWGQL

PAQR4

61

Q8N4S7
LMLYPLGPTAVVLSW

PTPRO

536

Q16827
TVAMWIPGVVPLSSL

PLIN1

246

O60240
AWAAPFLAMVPTVLS

OR6V1

146

Q8N148
GRLMPWIIFSTPLAV

MFSD2A

126

Q8NA29
TDGISWPFVLLIMPL

ATP2A2

1011

P16615
IIMHLLAVIGGPPFW

CEPT1

221

Q9Y6K0
MPSWIGAVILPLLGL

GPC6

1

Q9Y625
SVLTPDVALPGMRWV

DOCK6

686

Q96HP0
LPIIWLKPGESAMFL

DNAH3

4046

Q8TD57
MPQLSLSWLGLGPVA

CYP4F11

1

Q9HBI6
VRPTVLMPLWNVLGF

COQ7

106

Q99807
LEGTWMTPIPFIIAL

DNAI7

551

Q6TDU7
QPPVSIWLIVFGVVM

ACE2

736

Q9BYF1
RPVTPSLLVDWSMGI

MAP3K12

206

Q12852
AAIGVLVLSWYPPGM

MANEAL

181

Q5VSG8
ALWMAGTLLSPPSGV

C19orf54

136

Q5BKX5
MWPLTALLLLVPSSG

FCRLB

1

Q6BAA4
APLVLLPAWLVMVAC

GRIK4

6

Q16099
PSASPWMVALAVILT

BTN2A2

246

Q8WVV5
TGAPVLGLVLPMWAI

SLC20A2

201

Q08357
MGSAPWAPVLLLALG

DPP7

1

Q9UHL4
MPVPWFLLSLALGRS

IL17RC

1

Q8NAC3
PAMAPVGRLRLAWVA

TBRG4

21

Q969Z0
APITLMLAWSPAPTA

ICAM4

226

Q14773
IRGFWIVPDILGPTM

NUP88

466

Q99567
MAWTPPLLVLTLCTG

IGLV3-32

1

A0A0A0MS00
VWGVTPALHSPLMSV

NNT

516

Q13423
KSLWSGLPPTLVMAV

SLC25A40

101

Q8TBP6
LMDPPGTALAKLAVW

MED24

801

O75448
SPQPTWRLLAMLAGL

SLC39A4

396

Q6P5W5
MLSPAAVPVWSAGLE

SIX5

656

Q8N196
LAWPGLALPLVAMAA

TAOK2

1051

Q9UL54
RAVTLMPVAPLWAAL

SLC6A8

391

P48029
LWVIKASPAAIVFPM

SLC4A8

966

Q2Y0W8
SALADPSGLWVRMPL

SLC38A8

336

A6NNN8
NWGPHLIIVPTSVML

SRCAP

666

Q6ZRS2
PAVGWGLAIRKTPML

NPAP1

86

Q9NZP6
PISPMQWVGTVLVFL

SLC35B1

291

P78383
LVLSVTPMVPVGSVW

SMLR1

21

H3BR10
VVLIMVWDGIPLPMA

TET1

1516

Q8NFU7
PATAAVSAMKWGLLP

ADD2

231

P35612
LMWLAREGIVAPLPG

CEP164

46

Q9UPV0
LLAGLMVIVPVSWTA

CLDN4

126

O14493
APAWMLLSKIAGSSP

NCAPD3

716

P42695
MDPSVPIWIIIFGVI

CLTRN

136

Q9HBJ8
HLIPSPWLAMVLGLV

RHD

286

Q02161
HLIPSPWLAMVLGLV

RHCE

286

P18577
WLGDAVPGPVTRLLM

SLC16A13

271

Q7RTY0
AVIAATLFPLWPAEM

SEC62

206

Q99442
LVFGMVVPSVLVPWL

RHBDD2

156

Q6NTF9
KDAMWVPCLVSIPGL

FLT4

151

P35916
AWMPKATVQAVLGPL

SLC9B1

436

Q4ZJI4
DIPPLMRGLTWAALL

TBCK

466

Q8TEA7
TPGWPTTLLVVMGTL

DCT

466

P40126
MAVRPGLWPALLGIV

UNC5A

1

Q6ZN44
AQLPLWSPTSIMRGV

USP24

1486

Q9UPU5
DTVLLPGASVQLPMW

TRAPPC8

1021

Q9Y2L5
MAPWALLSPGVLVRT

ZDHHC12

1

Q96GR4
GIWTAPISPMALTML

ZSWIM1

21

Q9BR11
MLFLALGSPWAVELP

TMEM70

1

Q9BUB7
MPWPLLLLLAVSGAQ

TSKU

1

Q8WUA8
LVVPGCSWMPDITLI

TM6SF1

286

Q9BZW5
MPGLLNWITGAALPL

VWA5B1

1

Q5TIE3
MVPPVWTLLLLVGAA

ZAN

1

Q9Y493
TVPPATMRIWLLGGL

ART4

16

Q93070
IFWVLPDGSILKAPM

MXRA5

511

Q9NR99