Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEF-hand_dom_typ1

DRP2 DTNB

5.09e-056352IPR015153
DomainEF-hand_dom_typ2

DRP2 DTNB

5.09e-056352IPR015154
DomainEF-hand_2

DRP2 DTNB

5.09e-056352PF09068
DomainEF-hand_3

DRP2 DTNB

5.09e-056352PF09069
DomainZF_ZZ_2

DRP2 DTNB

5.12e-0418352PS50135
DomainZF_ZZ_1

DRP2 DTNB

5.12e-0418352PS01357
DomainZZ

DRP2 DTNB

5.12e-0418352PF00569
DomainZnf_ZZ

DRP2 DTNB

5.72e-0419352IPR000433
DomainZnF_ZZ

DRP2 DTNB

5.72e-0419352SM00291
DomainZF_PHD_2

KDM4C ASXL3 ZMYND8

7.42e-0495353PS50016
DomainZF_PHD_1

KDM4C ASXL3 ZMYND8

7.64e-0496353PS01359
DomainSpectrin

DRP2 SYNE2

8.42e-0423352PF00435
DomainSpectrin_repeat

DRP2 SYNE2

1.34e-0329352IPR002017
DomainSpectrin/alpha-actinin

DRP2 SYNE2

1.63e-0332352IPR018159
DomainSPEC

DRP2 SYNE2

1.63e-0332352SM00150
DomainBromodomain

ATAD2B ZMYND8

2.30e-0338352PF00439
DomainBROMODOMAIN_2

ATAD2B ZMYND8

2.67e-0341352PS50014
DomainBROMO

ATAD2B ZMYND8

2.80e-0342352SM00297
DomainBromodomain

ATAD2B ZMYND8

2.80e-0342352IPR001487
Domain-

ATAD2B ZMYND8

2.80e-03423521.20.920.10
DomainAAA

ATAD3A ATAD2B

4.27e-0352352PF00004
DomainATPase_AAA_core

ATAD3A ATAD2B

4.59e-0354352IPR003959
DomainPHD

KDM4C ZMYND8

1.21e-0289352SM00249
DomainZnf_PHD

KDM4C ZMYND8

1.26e-0291352IPR001965
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

XRN1 SECISBP2L DNA2 ANAPC5 PARG MOCOS

4.26e-0565035638777146
Pubmed

gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.

DRP2 DTNB

5.38e-051135216857187
Pubmed

Characterization of vertebrate cohesin complexes and their regulation in prophase.

PDS5A ANAPC5

8.89e-051435211076961
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L PDS5A HAUS6 KDM4C ATAD3A

1.28e-0449335515368895
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

PDS5A HAUS6 LARS2 ATAD3A PDPK1

1.57e-0451535531617661
Pubmed

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.

SECISBP2L SYNE2

4.20e-043035230480076
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

XRN1 PDS5A ATAD3A ATAD2B SYNE2

4.68e-0465335522586326
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

XRN1 SECISBP2L HAUS6 ANAPC5 PDPK1 MOCOS

5.39e-04103835626673895
Pubmed

PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.

DRP2 MYLK

7.87e-044135221282332
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ANAPC5 PDPK1 PARG MOCOS ZMYND8

1.01e-0377435515302935
Cytoband3p21.3

DLEC1 LARS2

9.40e-04593523p21.3
CytobandEnsembl 112 genes in cytogenetic band chr18q12

ASXL3 MOCOS

2.88e-03104352chr18q12
CytobandEnsembl 112 genes in cytogenetic band chr2p23

DTNB ATAD2B

5.80e-03149352chr2p23
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 DTNB

2.34e-041823291
GeneFamilyAAA ATPases

ATAD3A ATAD2B

2.05e-0353232413
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SECISBP2L PDS5A LARS2 KDM4C ATAD2B SYNE2 PARG ZMYND8

1.35e-05856358M4500
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5+_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS6 DNA2 LARS2 ASXL3

4.24e-06139354c300f953ff9c5e820ff16bcd9942d279b37b79db
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS6 DNA2 LARS2 ASXL3

4.24e-0613935495b19d7459d9b54162cf01d278462245d34802d5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DDIAS HAUS6 DLEC1 SYNE2

7.59e-061613545fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAS2R4 FCRL3 DTNB PARG

9.40e-0617035432917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L PDS5A SYNE2 PARG

1.49e-0519135460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L PDS5A SYNE2 PARG

1.49e-0519135409db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L PDS5A SYNE2 PARG

1.49e-05191354973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
DrugImidurea [39236-46-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A

ELK4 KDM4C ANKRD55 DTNB ZMYND8

1.27e-051993555481_UP
DrugAtractyloside potassium salt [102130-43-8]; Up 200; 5uM; HL60; HT_HG-U133A

PDS5A ZNF215 ELK4 ANKRD55 ZMYND8

1.30e-052003552573_UP
DiseaseT-Cell Lymphoma

KDM4C ASXL3

1.53e-0416342C0079772
Diseaselevel of Sphingomyelin (d40:2) in blood serum

ADAMTS3 SYNE2

3.21e-0423342OBA_2045181
Diseaselevel of Sphingomyelin (d38:1) in blood serum

ADAMTS3 SYNE2

5.49e-0430342OBA_2045180
Diseaseoxalate measurement

DLEC1 MYLK

6.25e-0432342EFO_0010517
Diseaseunipolar depression, bipolar disorder

ASXL3 SYNE2 ZMYND8

7.69e-04156343EFO_0003761, MONDO_0004985
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DRP2 DTNB

7.92e-0436342DOID:11723 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

FAM217B DLEC1 FCRL3 ANAPC5 PDPK1 SYNE2

1.29e-031074346C0006142
Diseasedepressive symptom measurement

ASXL3 ATAD2B SYNE2 ZMYND8

1.41e-03426344EFO_0007006
Diseasealcohol consumption measurement

XRN1 SECISBP2L PKD1L3 KDM4C CADPS IP6K2

2.69e-031242346EFO_0007878
Diseaseprostate carcinoma

BOD1 HAUS6 PKD1L3 SYNE2 MOCOS

3.34e-03891345EFO_0001663
Diseasefeeling "fed-up" measurement

LARS2 ATAD2B

3.48e-0376342EFO_0009588
Diseasehormone measurement

DDIAS ATAD2B

4.23e-0384342EFO_0004730

Protein segments in the cluster

PeptideGeneStartEntry
QQHQQKMCWLKAEGP

ATAD3A

611

Q9NVI7
CQMLLDNPWKSDSNQ

ANKRD55

486

Q3KP44
SQPFKQEWLNKHSMQ

ASXL3

1871

Q9C0F0
PNAVKALNEMWKCQN

PDS5A

496

Q29RF7
NQKSPFWEMSQAQLH

KCNJ5

281

P48544
SQHAQLWMLCDQKIQ

ANAPC5

501

Q9UJX4
QSEWHKMTVSKNCPD

CADPS

491

Q9ULU8
TQCLQHPWLMKDTKN

MYLK

1711

Q15746
SQLKHYNPWSMKCHQ

IP6K2

171

Q9UHH9
QRNPMDVWHNSANKC

ATAD2B

1116

Q9ULI0
WDNKHVKMPCSEQNL

PARG

506

Q86W56
MNAGPSWNKVQHSKN

FAM217B

1

Q9NTX9
TNTLKEMPWGHINNN

DDIAS

646

Q8IXT1
KQTKNNKWAHVMCAV

KDM4C

766

Q9H3R0
WMVVNHNGVCLSQKQ

MOCOS

616

Q96EN8
YKGHCMWKNANQQKQ

ADAMTS3

536

O15072
TQVVTNCWENKSKMN

KLHL15

461

Q96M94
QKPQNKHMICWTSND

ELK4

16

P28324
HLDKQEWNPTMNKNQ

BOD1

96

Q96IK1
SNQHQMKEHSSWKSP

DTNB

281

O60941
WSIQHTKENSANCPM

FCRL3

666

Q96P31
VSCNKPSTNKTMLWN

HAUS6

741

Q7Z4H7
KKASQPRNKNWMNHL

DLEC1

291

Q9Y238
DNKKNHQNIWLMPAS

DNA2

456

P51530
QQAHWPEHMKSCTQS

ZMYND8

1051

Q9ULU4
INHQAQTTCWDHPKM

DRP2

371

Q13474
AKKMWPQYCQHDNDT

SYNE2

4406

Q8WXH0
PQSWTQSNIKHMRKQ

LARS2

146

Q15031
MDPSGNAHKWCRKIQ

PDPK1

526

O15530
WIGQNVMPLKKHQDN

PKD1L3

81

Q7Z443
CQATQKKPWMEKNQT

SECISBP2L

316

Q93073
WKCPHCQVLQQGMVK

USP43

561

Q70EL4
KAECWSQKMSNKQPN

XRN1

1301

Q8IZH2
TWVNLQHPNNSKDMV

ZNF215

106

Q9UL58
HIQKMQKNATGFWNP

TAS2R4

206

Q9NYW5