Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hexose-phosphate:phosphate antiporter activity	SLC37A1 SLC37A2	2.58e-05	4	42	2	GO:0015526
GeneOntologyMolecularFunction	hexose phosphate transmembrane transporter activity	SLC37A1 SLC37A2	2.58e-05	4	42	2	GO:0015119
GeneOntologyMolecularFunction	glucose-6-phosphate transmembrane transporter activity	SLC37A1 SLC37A2	2.58e-05	4	42	2	GO:0015152
GeneOntologyMolecularFunction	glucose 6-phosphate:phosphate antiporter activity	SLC37A1 SLC37A2	2.58e-05	4	42	2	GO:0061513
GeneOntologyMolecularFunction	scaffold protein binding	CHRFAM7A CIT CHRNA7 RYR2	4.31e-05	93	42	4	GO:0097110
GeneOntologyMolecularFunction	organophosphate:phosphate antiporter activity	SLC37A1 SLC37A2	9.01e-05	7	42	2	GO:0015315
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC37A1 SLC37A2 SLC25A21 SLC10A1 TMC3 CHRFAM7A SLC7A14 PANX3 CHRNA7 RYR2	1.29e-04	1180	42	10	GO:0022857
GeneOntologyMolecularFunction	transporter activity	SLC37A1 SLC37A2 SLC25A21 SLC10A1 TMC3 CHRFAM7A SLC7A14 PANX3 CHRNA7 RYR2	2.66e-04	1289	42	10	GO:0005215
GeneOntologyMolecularFunction	acetylcholine binding	CHRFAM7A CHRNA7	3.32e-04	13	42	2	GO:0042166
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC37A1 SLC37A2 SLC25A21 SLC10A1 SLC7A14	3.59e-04	293	42	5	GO:0008514
GeneOntologyMolecularFunction	chloride channel regulator activity	CHRFAM7A CHRNA7	4.46e-04	15	42	2	GO:0017081
GeneOntologyMolecularFunction	adenylate cyclase binding	CHRFAM7A CHRNA7	5.09e-04	16	42	2	GO:0008179
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRFAM7A CHRNA7	5.76e-04	17	42	2	GO:0022848
GeneOntologyMolecularFunction	toxic substance binding	CHRFAM7A CHRNA7	6.47e-04	18	42	2	GO:0015643
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRFAM7A CHRNA7	1.06e-03	23	42	2	GO:0015464
GeneOntologyMolecularFunction	phosphate transmembrane transporter activity	SLC37A1 SLC37A2	1.16e-03	24	42	2	GO:0005315
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC37A1 SLC37A2	2.06e-03	32	42	2	GO:0005452
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	ANXA8 ANXA8L1	2.46e-03	35	42	2	GO:0043325
GeneOntologyMolecularFunction	calcium channel activity	PANX3 CHRNA7 RYR2	2.52e-03	129	42	3	GO:0005262
GeneOntologyMolecularFunction	monoatomic ion channel activity	TMC3 CHRFAM7A PANX3 CHRNA7 RYR2	2.65e-03	459	42	5	GO:0005216
GeneOntologyMolecularFunction	antiporter activity	SLC37A1 SLC37A2 SLC25A21	3.04e-03	138	42	3	GO:0015297
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC37A1 SLC37A2	3.05e-03	39	42	2	GO:0015605
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	CHRFAM7A CHRNA7 RYR2	3.17e-03	140	42	3	GO:0099094
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC37A1 SLC37A2 SLC25A21 SLC10A1	3.40e-03	296	42	4	GO:0015291
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	CHRFAM7A CHRNA7	3.69e-03	43	42	2	GO:0005231
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	PANX3 CHRNA7 RYR2	3.92e-03	151	42	3	GO:0015085
GeneOntologyMolecularFunction	phosphatidylinositol binding	ANXA8 ZFYVE9 VPS13B ANXA8L1	4.29e-03	316	42	4	GO:0035091
GeneOntologyMolecularFunction	channel activity	TMC3 CHRFAM7A PANX3 CHRNA7 RYR2	4.70e-03	525	42	5	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TMC3 CHRFAM7A PANX3 CHRNA7 RYR2	4.74e-03	526	42	5	GO:0022803
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	ANXA8 ANXA8L1	4.77e-03	49	42	2	GO:0005547
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC37A1 SLC37A2 SLC10A1 PANX3 CHRNA7 RYR2	4.79e-03	758	42	6	GO:0015318
GeneOntologyMolecularFunction	gated channel activity	TMC3 CHRFAM7A CHRNA7 RYR2	5.22e-03	334	42	4	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	CHRFAM7A PANX3 CHRNA7 RYR2	5.73e-03	343	42	4	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC10A1 TMC3 CHRFAM7A PANX3 CHRNA7 RYR2	5.96e-03	793	42	6	GO:0015075
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRFAM7A CHRNA7	6.41e-03	57	42	2	GO:1904315
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC37A1 SLC37A2	6.85e-03	59	42	2	GO:1901505
GeneOntologyMolecularFunction	calcium-dependent phospholipid binding	ANXA8 ANXA8L1	7.08e-03	60	42	2	GO:0005544
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	CHRFAM7A CHRNA7	7.08e-03	60	42	2	GO:0099529
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	CHRFAM7A CHRNA7 RYR2	7.74e-03	193	42	3	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	CHRFAM7A CHRNA7 RYR2	8.18e-03	197	42	3	GO:0022834
GeneOntologyMolecularFunction	transmitter-gated channel activity	CHRFAM7A CHRNA7	8.26e-03	65	42	2	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	CHRFAM7A CHRNA7	8.26e-03	65	42	2	GO:0022824
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	ANXA8 VPS13B ANXA8L1	8.41e-03	199	42	3	GO:1901981
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC25A21 SLC10A1 SLC7A14	9.36e-03	207	42	3	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC25A21 SLC10A1 SLC7A14	9.49e-03	208	42	3	GO:0005342
GeneOntologyMolecularFunction	phosphatidylserine binding	ANXA8 ANXA8L1	1.03e-02	73	42	2	GO:0001786
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	CHRFAM7A CHRNA7	1.09e-02	75	42	2	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRFAM7A CHRNA7	1.14e-02	77	42	2	GO:0005230
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC10A1 CHRFAM7A PANX3 CHRNA7 RYR2	1.23e-02	664	42	5	GO:0008324
GeneOntologyBiologicalProcess	positive regulation of heart rate	ADA CHRFAM7A CHRNA7 RYR2	7.43e-07	35	42	4	GO:0010460
GeneOntologyBiologicalProcess	positive regulation of heart contraction	ADA CHRFAM7A CHRNA7 RYR2	2.94e-06	49	42	4	GO:0045823
GeneOntologyBiologicalProcess	positive regulation of blood circulation	ADA CHRFAM7A CHRNA7 RYR2	4.04e-06	53	42	4	GO:1903524
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	4.05e-06	2	42	2	GO:0001988
GeneOntologyBiologicalProcess	negative regulation of phospholipase A2 activity	ANXA8 ANXA8L1	1.21e-05	3	42	2	GO:1900138
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	1.21e-05	3	42	2	GO:0001982
GeneOntologyBiologicalProcess	generation of ovulation cycle rhythm	CHRFAM7A CHRNA7	2.42e-05	4	42	2	GO:0060112
GeneOntologyBiologicalProcess	sensory processing	CHRFAM7A CHRNA7	4.03e-05	5	42	2	GO:0050893
GeneOntologyBiologicalProcess	negative regulation of phospholipase activity	ANXA8 ANXA8L1	4.03e-05	5	42	2	GO:0010519
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	CHRFAM7A CHRNA7	6.04e-05	6	42	2	GO:0001978
GeneOntologyBiologicalProcess	hexose phosphate transport	SLC37A1 SLC37A2	8.45e-05	7	42	2	GO:0015712
GeneOntologyBiologicalProcess	glucose-6-phosphate transport	SLC37A1 SLC37A2	8.45e-05	7	42	2	GO:0015760
GeneOntologyBiologicalProcess	negative regulation of serine-type peptidase activity	ANXA8 ANXA8L1	1.12e-04	8	42	2	GO:1902572
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by baroreceptor feedback	CHRFAM7A CHRNA7	1.12e-04	8	42	2	GO:0003025
GeneOntologyBiologicalProcess	negative regulation of serine-type endopeptidase activity	ANXA8 ANXA8L1	1.12e-04	8	42	2	GO:1900004
GeneOntologyBiologicalProcess	regulation of heart rate	ADA CHRFAM7A CHRNA7 RYR2	1.36e-04	129	42	4	GO:0002027
GeneOntologyBiologicalProcess	positive regulation of CoA-transferase activity	CHRFAM7A CHRNA7	1.44e-04	9	42	2	GO:1905920
GeneOntologyBiologicalProcess	regulation of serine-type peptidase activity	ANXA8 ANXA8L1	1.80e-04	10	42	2	GO:1902571
GeneOntologyBiologicalProcess	regulation of phospholipase A2 activity	ANXA8 ANXA8L1	1.80e-04	10	42	2	GO:0032429
GeneOntologyBiologicalProcess	regulation of serine-type endopeptidase activity	ANXA8 ANXA8L1	1.80e-04	10	42	2	GO:1900003
GeneOntologyBiologicalProcess	regulation of CoA-transferase activity	CHRFAM7A CHRNA7	2.20e-04	11	42	2	GO:1905918
GeneOntologyBiologicalProcess	behavioral response to nicotine	CHRFAM7A CHRNA7	2.20e-04	11	42	2	GO:0035095
GeneOntologyBiologicalProcess	response to food	MPO CHRFAM7A CHRNA7	2.24e-04	58	42	3	GO:0032094
GeneOntologyBiologicalProcess	regulation of synapse structural plasticity	CHRFAM7A CHRNA7	2.64e-04	12	42	2	GO:0051823
GeneOntologyBiologicalProcess	regulation of synaptic transmission, dopaminergic	CHRFAM7A CHRNA7	3.11e-04	13	42	2	GO:0032225
GeneOntologyBiologicalProcess	regulation of interleukin-1 production	JAK2 CHRFAM7A PANX3 CHRNA7	3.49e-04	165	42	4	GO:0032652
GeneOntologyBiologicalProcess	negative regulation of lipase activity	ANXA8 ANXA8L1	3.63e-04	14	42	2	GO:0060192
GeneOntologyBiologicalProcess	postsynaptic signal transduction	JAK2 CHRFAM7A CHRNA7	3.75e-04	69	42	3	GO:0098926
GeneOntologyBiologicalProcess	interleukin-1 production	JAK2 CHRFAM7A PANX3 CHRNA7	3.99e-04	171	42	4	GO:0032612
GeneOntologyBiologicalProcess	dendrite arborization	CHRFAM7A CHRNA7	4.18e-04	15	42	2	GO:0140059
GeneOntologyBiologicalProcess	phosphate ion transmembrane transport	SLC37A1 SLC37A2	4.18e-04	15	42	2	GO:0035435
GeneOntologyBiologicalProcess	behavioral response to ethanol	CHRFAM7A CHRNA7	5.40e-04	17	42	2	GO:0048149
GeneOntologyBiologicalProcess	regulation of amyloid fibril formation	CHRFAM7A CHRNA7	6.77e-04	19	42	2	GO:1905906
GeneOntologyBiologicalProcess	regulation of response to drug	CHRFAM7A CHRNA7	8.29e-04	21	42	2	GO:2001023
GeneOntologyBiologicalProcess	regulation of phospholipase activity	ANXA8 ANXA8L1	9.11e-04	22	42	2	GO:0010517
GeneOntologyBiologicalProcess	positive regulation of amyloid-beta formation	CHRFAM7A CHRNA7	9.97e-04	23	42	2	GO:1902004
GeneOntologyBiologicalProcess	nervous system process involved in regulation of systemic arterial blood pressure	CHRFAM7A CHRNA7	1.09e-03	24	42	2	GO:0001976
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRFAM7A STXBP5 CHRNA7	5.60e-06	18	41	3	GO:0005892
GeneOntologyCellularComponent	spine apparatus membrane	CHRFAM7A CHRNA7	1.12e-05	3	41	2	GO:0098897
GeneOntologyCellularComponent	spine apparatus	CHRFAM7A CHRNA7	1.34e-04	9	41	2	GO:0097444
GeneOntologyCellularComponent	glycinergic synapse	CHRFAM7A CHRNA7	6.97e-04	20	41	2	GO:0098690
GeneOntologyCellularComponent	axolemma	CHRFAM7A CHRNA7	7.70e-04	21	41	2	GO:0030673
GeneOntologyCellularComponent	cholinergic synapse	CHRFAM7A CHRNA7	8.46e-04	22	41	2	GO:0098981
MousePheno	airway basal cell hyperplasia	CHRFAM7A CHRNA7	5.40e-06	2	33	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRFAM7A CHRNA7	5.40e-06	2	33	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRFAM7A CHRNA7	5.40e-06	2	33	2	MP:0011113
MousePheno	abnormal bile duct physiology	PKHD1 SLC10A1 ADA	2.66e-05	25	33	3	MP:0003252
MousePheno	abnormal nicotine-mediated receptor currents	CHRFAM7A CHRNA7	3.23e-05	4	33	2	MP:0009475
MousePheno	failure of neuromuscular synapse presynaptic differentiation	CHRFAM7A CHRNA7	8.06e-05	6	33	2	MP:0001054
MousePheno	abnormal GABAergic neuron physiology	CHRFAM7A CHRNA7	1.50e-04	8	33	2	MP:0011987
MousePheno	impaired spatial working memory	CHRFAM7A CHRNA7	3.51e-04	12	33	2	MP:0014370
MousePheno	decreased erythroblast number	CHRFAM7A CHRNA7	3.51e-04	12	33	2	MP:0011179
MousePheno	abnormal seizure response to pharmacological agent	CHRFAM7A CIT CHRNA7 RYR2	3.79e-04	147	33	4	MP:0000950
Domain	AnnexinVIII	ANXA8 ANXA8L1	4.47e-06	2	40	2	IPR009115
Domain	Sugar_P_transporter	SLC37A1 SLC37A2	2.68e-05	4	40	2	IPR000849
Domain	Annexin	ANXA8 ANXA8L1	3.44e-04	13	40	2	PF00191
Domain	ANX	ANXA8 ANXA8L1	3.44e-04	13	40	2	SM00335
Domain	ANNEXIN	ANXA8 ANXA8L1	3.44e-04	13	40	2	PS00223
Domain	Annexin_repeat	ANXA8 ANXA8L1	3.44e-04	13	40	2	IPR018502
Domain	-	ANXA8 ANXA8L1	3.44e-04	13	40	2	1.10.220.10
Domain	Annexin_repeat_CS	ANXA8 ANXA8L1	3.44e-04	13	40	2	IPR018252
Domain	Annexin	ANXA8 ANXA8L1	4.00e-04	14	40	2	IPR001464
Domain	Acetylcholine_rcpt_TM	CHRFAM7A CHRNA7	1.10e-03	23	40	2	IPR027361
Domain	-	CHRFAM7A CHRNA7	1.10e-03	23	40	2	1.20.120.370
Domain	Neurotransmitter_ion_chnl_CS	CHRFAM7A CHRNA7	4.18e-03	45	40	2	IPR018000
Domain	Neur_chan_memb	CHRFAM7A CHRNA7	4.36e-03	46	40	2	PF02932
Domain	Neur_chan_LBD	CHRFAM7A CHRNA7	4.55e-03	47	40	2	PF02931
Domain	Neur_channel	CHRFAM7A CHRNA7	4.55e-03	47	40	2	IPR006201
Domain	Neur_chan_lig-bd	CHRFAM7A CHRNA7	4.55e-03	47	40	2	IPR006202
Domain	NEUROTR_ION_CHANNEL	CHRFAM7A CHRNA7	4.55e-03	47	40	2	PS00236
Domain	Neurotrans-gated_channel_TM	CHRFAM7A CHRNA7	4.55e-03	47	40	2	IPR006029
Domain	-	CHRFAM7A CHRNA7	4.55e-03	47	40	2	2.70.170.10
Domain	-	KBTBD6 KBTBD7	4.74e-03	48	40	2	2.120.10.80
Domain	Kelch-typ_b-propeller	KBTBD6 KBTBD7	6.18e-03	55	40	2	IPR015915
Domain	Kelch	KBTBD6 KBTBD7	6.85e-03	58	40	2	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KBTBD6 KBTBD7	7.08e-03	59	40	2	IPR011043
Domain	BACK	KBTBD6 KBTBD7	7.32e-03	60	40	2	SM00875
Domain	BACK	KBTBD6 KBTBD7	7.56e-03	61	40	2	PF07707
Domain	BACK	KBTBD6 KBTBD7	7.56e-03	61	40	2	IPR011705
Pubmed	Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway.	JAK2 CHRFAM7A CHRNA7	6.54e-09	4	42	3	16025117
Pubmed	α7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage.	JAK2 CHRFAM7A CHRNA7	6.54e-09	4	42	3	28529954
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	38070724
Pubmed	Inflammatory cytokines decrease the expression of nicotinic acetylcholine receptor during the cell maturation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19626424
Pubmed	Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	17012698
Pubmed	Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	26451017
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	34453977
Pubmed	Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24757672
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	27129924
Pubmed	Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	17291692
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19344760
Pubmed	Loss of α7nAChR enhances endothelial-to-mesenchymal transition after myocardial infarction via NF-κB activation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	35926661
Pubmed	The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	17640819
Pubmed	Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23431157
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	29114104
Pubmed	TaqI polymorphisms at the annexin VIII locus (ANX8).	ANXA8 ANXA8L1	1.42e-06	2	42	2	1364010
Pubmed	Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.	ANXA8 ANXA8L1	1.42e-06	2	42	2	24769558
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24836856
Pubmed	Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	31904546
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	35678315
Pubmed	Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33117372
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	25157794
Pubmed	Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19615981
Pubmed	Splenic nerve denervation attenuates depression-like behaviors in Chrna7 knock-out mice via the spleen-gut-brain axis.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	38944290
Pubmed	Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	28243714
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22246862
Pubmed	Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24298024
Pubmed	Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	29975102
Pubmed	α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	29580318
Pubmed	Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	35479080
Pubmed	[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].	CHRFAM7A CHRNA7	1.42e-06	2	42	2	38597441
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22688057
Pubmed	α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22820264
Pubmed	Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33953172
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	32028688
Pubmed	Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	30089821
Pubmed	Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	20615555
Pubmed	Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	15896732
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	21501254
Pubmed	α7-cholinergic receptor mediates vagal induction of splenic norepinephrine.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	21339364
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	21368056
Pubmed	Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.	ANXA8 ANXA8L1	1.42e-06	2	42	2	29306076
Pubmed	Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24289814
Pubmed	Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19949071
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	1400473
Pubmed	Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	17204496
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	26937017
Pubmed	α7 nicotinic receptors play a role in regulation of cardiac hemodynamics.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	37017608
Pubmed	Impaired hippocampal theta oscillations in the mice null alpha7 nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23795917
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	36603528
Pubmed	Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	20592195
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	26650489
Pubmed	Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	11854451
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22848433
Pubmed	Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23842742
Pubmed	Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.	SLC37A1 SLC37A2	1.42e-06	2	42	2	11112347
Pubmed	Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	17292512
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	35413868
Pubmed	Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23637989
Pubmed	Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).	CHRFAM7A CHRNA7	1.42e-06	2	42	2	9782083
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	29261717
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22490926
Pubmed	Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	36997969
Pubmed	A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	15364017
Pubmed	Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23769729
Pubmed	Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	15944242
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	11790782
Pubmed	A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33422641
Pubmed	Nicotinic ACh receptor α7 inhibits PDGF-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase sirtuin 3.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	30270436
Pubmed	Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.	ANXA8 ANXA8L1	1.42e-06	2	42	2	21344395
Pubmed	Activation of α-7 Nicotinic Acetylcholine Receptor Attenuates Cardiac Inflammation Through NLRP3/Caspase-1/IL-18 Pathway.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	34988776
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	24326163
Pubmed	Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33398432
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23811428
Pubmed	beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	20374280
Pubmed	Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	38185761
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	20720594
Pubmed	α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	22624500
Pubmed	Involvement of acetylcholine-α7nAChR in the protective effects of arterial baroreflex against ischemic stroke.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	23106973
Pubmed	Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.	CHRFAM7A CHRNA7	1.42e-06	2	42	2	33902624
Cytoband	13q14.11	KBTBD6 KBTBD7	5.93e-04	39	42	2	13q14.11
Cytoband	10q11.22	ANXA8 ANXA8L1	6.55e-04	41	42	2	10q11.22
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	SLC37A2 PANX3 OR6X1	7.22e-04	191	42	3	chr11q24
Cytoband	11q24.2	SLC37A2 PANX3	1.54e-03	63	42	2	11q24.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	CHRFAM7A CHRNA7	3.82e-03	100	42	2	chr15q13
GeneFamily	Annexins\|Endogenous ligands	ANXA8 ANXA8L1	1.92e-04	13	29	2	404
GeneFamily	Solute carriers	SLC37A1 SLC37A2 SLC25A21 SLC10A1 SLC7A14	3.74e-04	395	29	5	752
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2	SLC37A1 SLC37A2 GRTP1 ADA CHRFAM7A CHRNA7 HPS1	1.19e-05	504	41	7	MM830
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)\|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPO JAK2 UHRF1 SLC25A21 KBTBD6 STXBP5 KBTBD7	5.49e-10	192	42	7	072281344d58e85c9a290750b488d0c101f75d54
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPO KBTBD6 DNAH10 STXBP5 KBTBD7	9.55e-07	190	42	5	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANXA8 PACRG DNAH10 DAW1 ANXA8L1	9.55e-07	190	42	5	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	MPO UHRF1 KBTBD6 CIT STXBP5	1.20e-06	199	42	5	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	MPO UHRF1 KBTBD6 CIT STXBP5	1.20e-06	199	42	5	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA AGPAT2	2.01e-05	171	42	4	fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA AGPAT2	2.01e-05	171	42	4	f15594fd4d709920733de9376a391dedc62b65de
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPO SLC37A1 UHRF1 ADA	2.11e-05	173	42	4	b367b62309389e8b6a65de83c2434dc8ec905985
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMC3 CHRFAM7A SLC7A14 RYR2	2.63e-05	183	42	4	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	droplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PACRG DNAH10 TMC3 DAW1	2.63e-05	183	42	4	3991830726d05cf19606d540de04093985b7bdeb
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PACRG DNAH10 TMC3 DAW1	2.63e-05	183	42	4	cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMC3 CHRFAM7A SLC7A14 RYR2	2.80e-05	186	42	4	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA8 PACRG DNAH10 DAW1	2.86e-05	187	42	4	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA8 PACRG DNAH10 DAW1	2.86e-05	187	42	4	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	10x5'v1-week_17-19-Hematopoietic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SLC37A1 SLC25A21 GRTP1 RYR2	2.92e-05	188	42	4	c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PKHD1 SLC37A1 PTPRU ANXA8L1	3.57e-05	198	42	4	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PKHD1 SLC37A1 PTPRU ANXA8L1	3.64e-05	199	42	4	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	UHRF1 ANXA8 GRTP1 ANXA8L1	3.64e-05	199	42	4	fe22833e69928a1478df265e1c356c463611dedd
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PKHD1 SLC37A1 PTPRU ANXA8L1	3.64e-05	199	42	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PKHD1 SLC37A1 PTPRU ANXA8L1	3.72e-05	200	42	4	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PKHD1 SLC10A1 IQCM	4.14e-05	71	42	3	b0dbb059a7d05f825da608879b23aeebd6e9e61f
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PKHD1 SLC10A1 IQCM	4.14e-05	71	42	3	149504ce72da0730074ea436fc2034ce8cb585d5
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3-Inhibitory_Neuron.Gad1Gad2.Six3-Pvalb_(Thalamic_reticular_nucleus,_TRN+)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	KBTBD6 IQCM CHRNA7	5.07e-05	76	42	3	14350e0e8fc43531f33f6ed4e583e94a13d1dde5
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	KBTBD6 IQCM CHRNA7	5.07e-05	76	42	3	492cdcbc577a9334af8e4ded469da17bc7e79025
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3-Inhibitory_Neuron.Gad1Gad2.Six3-Pvalb_(Thalamic_reticular_nucleus,_TRN+)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	KBTBD6 IQCM CHRNA7	5.07e-05	76	42	3	539f0076d0571be049c35541a3b281f86ddbecd6
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Stmn2))\|Striatum / BrainAtlas - Mouse McCarroll V32	UHRF1 KBTBD6 TMC3	8.40e-05	90	42	3	7efc3437489c8587b9805547da1095f50d20cf6d
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANXA8 DNAH10 DAW1	1.83e-04	117	42	3	454efceabe739cdf293f81c8a938811f12321a47
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANXA8 DNAH10 DAW1	1.83e-04	117	42	3	91936a3ffbfa29024ced9d01df962b4ccfaf8966
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANXA8 DNAH10 DAW1	1.83e-04	117	42	3	409b3ab16786bced8c9bc9c0e89b0078402f365a
ToppCell	Hippocampus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANXA8 DNAH10 DAW1	1.83e-04	117	42	3	e33ec9044541d2ef53f6633891238559b01b7957
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 CIT RYR2	2.61e-04	132	42	3	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC10A1 PIGZ RYR2	2.84e-04	136	42	3	a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC10A1 PIGZ RYR2	2.91e-04	137	42	3	8e2fa2ef8becace96a68bb85c002329110902fbb
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 SLC10A1	3.50e-04	146	42	3	74009a2921359a8352afbaea8c325a3743622543
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 SLC10A1	3.50e-04	146	42	3	cb19f2bb6832d11fe69b670df49eac096a378a9d
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PACRG DNAH10 DAW1	4.09e-04	154	42	3	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PACRG DNAH10 DAW1	4.09e-04	154	42	3	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PACRG IQCM ANXA8L1	4.25e-04	156	42	3	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	4.58e-04	160	42	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	4.58e-04	160	42	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SLC37A2 CIT STXBP5	4.58e-04	160	42	3	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PKHD1 PACRG RALGPS1	5.01e-04	165	42	3	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PKHD1 PACRG RALGPS1	5.01e-04	165	42	3	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|bone_marrow / Manually curated celltypes from each tissue	MPO UHRF1 CCM2L	5.09e-04	166	42	3	20f248d95c86eb52a1efe9abe73123fbe4206caf
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA	5.27e-04	168	42	3	260c768468dff51888f7a68e5424bb174dbaa759
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA	5.27e-04	168	42	3	18d7719a76620d5e5698f9ffd08b4ad4cb7c13f8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC10A1 DAW1 ANXA8L1	5.37e-04	169	42	3	6937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC10A1 DAW1 ANXA8L1	5.37e-04	169	42	3	0cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	5.37e-04	169	42	3	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPO UHRF1 ADA	5.46e-04	170	42	3	8d6419ffe7dc1a0483c174d8e4b29704895eb9cf
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRU STXBP5 PANX3	5.55e-04	171	42	3	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRU STXBP5 PANX3	5.55e-04	171	42	3	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRU ADA AGPAT2	5.55e-04	171	42	3	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 ADA	5.55e-04	171	42	3	c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRU ADA AGPAT2	5.55e-04	171	42	3	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PKHD1 ANXA8 ANXA8L1	5.65e-04	172	42	3	e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	MPO PACRG DNAH10	5.65e-04	172	42	3	6b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	JAK2 CCM2L VPS13B	5.65e-04	172	42	3	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ANXA8 DAW1 ANXA8L1	5.74e-04	173	42	3	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ANXA8 DAW1 ANXA8L1	5.74e-04	173	42	3	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANXA8 PACRG DNAH10	5.84e-04	174	42	3	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANXA8 PACRG DNAH10	5.94e-04	175	42	3	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 RALGPS1	5.94e-04	175	42	3	db6be3e9e339918418fcaf9001ea15207aa6c993
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 SLC10A1 AGPAT2	5.94e-04	175	42	3	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 RALGPS1	5.94e-04	175	42	3	8acac10c9eedccebcf3a3fe31bfee35afa54579f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANXA8 SLC25A21 PTPRU	6.14e-04	177	42	3	ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANXA8 SLC25A21 PTPRU	6.14e-04	177	42	3	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 RALGPS1	6.24e-04	178	42	3	5ac5257d88fa0dc67714881d6f005f6cea925710
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 GRTP1 KBTBD7	6.24e-04	178	42	3	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TMC3 CHRFAM7A SLC7A14	6.34e-04	179	42	3	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 POGLUT3	6.45e-04	180	42	3	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMC3 CHRFAM7A SLC7A14	6.45e-04	180	42	3	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANXA8 GRTP1 ANXA8L1	6.45e-04	180	42	3	535a890bde0d978b461c2d4c571529b585c76b21
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIT STXBP5 AGPAT2	6.55e-04	181	42	3	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIT STXBP5 AGPAT2	6.55e-04	181	42	3	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	Endothelial-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	UHRF1 SLC25A21 CCM2L	6.55e-04	181	42	3	4fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCell	PBMC-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	UHRF1 POGLUT3 SLC10A1	6.66e-04	182	42	3	4774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 AGPAT2	6.66e-04	182	42	3	81c394959414173016426961478f670cd822f8b3
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	ANXA8 PTPRU ANXA8L1	6.66e-04	182	42	3	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	ANXA8 PTPRU ANXA8L1	6.66e-04	182	42	3	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UHRF1 AGPAT2	6.66e-04	182	42	3	41a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCell	facs\|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC37A1 GRTP1 AGPAT2	6.66e-04	182	42	3	08f775135b451be709f5fc8e1cbcf63425794a2e
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PACRG CHRFAM7A SLC7A14	6.76e-04	183	42	3	91764095f7ea4bc806ef6c7b841fc5e5e90faf5f
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	PACRG DNAH10 DAW1	6.76e-04	183	42	3	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	PACRG DNAH10 DAW1	6.76e-04	183	42	3	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	ANXA8 PTPRU ANXA8L1	6.76e-04	183	42	3	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-St18_(Lateral_CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MPO PANX3	6.82e-04	41	42	2	083d2aab96ba9449797f955507c4a1be51ac5c8d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	6.87e-04	184	42	3	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	6.87e-04	184	42	3	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 DNAH10 RYR2	6.87e-04	184	42	3	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA8 PACRG DNAH10	6.87e-04	184	42	3	afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|lymph-node_spleen / Manually curated celltypes from each tissue	MPO UHRF1 AGPAT2	6.87e-04	184	42	3	f93373fcde5c31f4ffe67ca0f3ea7f4e906dc88b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PACRG DNAH10 DAW1	6.87e-04	184	42	3	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA8 PACRG DNAH10	6.87e-04	184	42	3	a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHRFAM7A SLC7A14 CHRNA7	6.98e-04	185	42	3	79cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC37A2 SLC10A1 DNAH10	6.98e-04	185	42	3	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA	6.98e-04	185	42	3	53854a9ec87c24c360541c83d86d8fafb303ad58
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	PACRG DNAH10 DAW1	6.98e-04	185	42	3	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PTPRU ADA	6.98e-04	185	42	3	a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PKHD1 PACRG HECTD4	6.98e-04	185	42	3	1d874608aa2062024323512f68889219471b2f00
Drug	PNU-282987	MPO JAK2 CHRNA7	1.89e-07	7	41	3	ctd:C498513
Drug	1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea	JAK2 CHRNA7	3.16e-06	2	41	2	ctd:C508388
Drug	anabaseine	MPO CHRFAM7A CHRNA7	1.07e-05	24	41	3	CID000018985
Drug	tetracaine	CHRFAM7A CHRNA7 RYR2 AGPAT2	1.89e-05	88	41	4	CID000005411
Drug	At 5	MPO SLC25A21	1.89e-05	4	41	2	CID000038267
Drug	ailanthoidol	MPO SLC25A21	1.89e-05	4	41	2	CID005316929
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A	SLC25A21 RALGPS1 VPS13B RYR2 HPS1	2.49e-05	194	41	5	3404_UP
Drug	M3/M4	CHRFAM7A CHRNA7 RYR2	2.59e-05	32	41	3	CID000486507
Drug	Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A	JAK2 PTPRU ZFYVE9 PIGZ HPS1	2.75e-05	198	41	5	2799_DN
Drug	gallamine	CHRFAM7A CHRNA7 HPS1	3.41e-05	35	41	3	CID000003450
Drug	1,2-dichlorohexafluorocyclobutane	CHRFAM7A CHRNA7 RYR2	4.04e-05	37	41	3	CID000009643
Drug	indolebutyric acid	MPO ADA	4.72e-05	6	41	2	ctd:C014612
Disease	cognitive disorder (implicated_via_orthology)	CHRFAM7A CHRNA7	2.54e-05	6	39	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRFAM7A CHRNA7	2.54e-05	6	39	2	DOID:7148 (biomarker_via_orthology)
Disease	nicotine dependence (implicated_via_orthology)	CHRFAM7A CHRNA7	1.11e-04	12	39	2	DOID:0050742 (implicated_via_orthology)
Disease	Ischemic stroke, tissue plasminogen activator measurement	STXBP5 HECTD4	1.77e-04	15	39	2	EFO_0004791, HP_0002140
Disease	factor VIII measurement, Ischemic stroke	STXBP5 HECTD4	2.87e-04	19	39	2	EFO_0004630, HP_0002140
Disease	Ischemic stroke, von Willebrand factor measurement	STXBP5 HECTD4	7.23e-04	30	39	2	EFO_0004629, HP_0002140
Disease	myeloid white cell count	MPO POGLUT3 DNAH10 CIT STXBP5 HECTD4	1.34e-03	937	39	6	EFO_0007988
Disease	venous thromboembolism, response to antineoplastic agent	PKHD1 IQCM	1.35e-03	41	39	2	EFO_0004286, GO_0097327
Disease	fibrinogen measurement, tissue plasminogen activator measurement	STXBP5 HECTD4	1.63e-03	45	39	2	EFO_0004623, EFO_0004791
Disease	reaction time measurement	PKHD1 PTPRU PACRG DNAH10 HECTD4	1.67e-03	658	39	5	EFO_0008393
Disease	neutrophil count	MPO JAK2 UHRF1 POGLUT3 CIT STXBP5 HECTD4	2.01e-03	1382	39	7	EFO_0004833
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	STXBP5 HECTD4	2.51e-03	56	39	2	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791

Protein segments in the cluster

Peptide	Gene	Start	Entry
RELLDLLYKAYGMPP	ADA	341	P00813
MLLREYRLGLPIQDY	CCM2L	436	Q9NUG4
YLVMEYQPGGDLLSL	CIT	171	O14578
MRRRTLYYGLNLLIP	CHRNA7	226	P36544
MVGKALVPYYRQILP	PACRG	181	Q96M98
MVPSIPYLGIYLLDL	RALGPS1	196	Q5JS13
RMLELLYPFPVHLYL	IQCM	161	A0A1B0GVH7
GRRNLKLIMEYLPYG	JAK2	921	O60674
GKFERLIVALMYPPY	ANXA8	81	P13928
RLGPGGAVMLLVYEY	SLC25A21	276	Q9BQT8
DYLPLVLGPTAMRKY	MPO	461	P05164
LLLRYYPPGIMLEYE	DAW1	6	Q8N136
MRYGDLLYKSLVPVP	KBTBD7	301	Q8WVZ9
VLSRALMYIPQLGKY	HECTD4	1691	Q9Y4D8
LMYIPQLGKYAESIL	HECTD4	1696	Q9Y4D8
VSLLYGAVLFMYLRP	OR6X1	246	Q8NH79
MRRRTLYYGLNLLIP	CHRFAM7A	136	Q494W8
RGYMGLDDILLLSYP	PTPRU	171	Q92729
PYSLLALALLMYLPV	PANX3	111	Q96QZ0
LGMMPLLLYIYSRGI	SLC10A1	131	Q14973
GERLPIRYYLTFGML	SLC37A1	121	P57057
RLPLRYYLSAGMLLS	SLC37A2	111	Q8TED4
GKFERLIVALMYPPY	ANXA8L1	81	Q5VT79
LVGRILPDYYSPAML	GRTP1	181	Q5TC63
VPIGMLGGDYYRKLL	HPS1	636	Q92902
YEYMGLNGRLVITPL	DNAH10	1796	Q8IVF4
LYAIENKYMPGLLRA	RYR2	1686	Q92736
MRYGDLLYKSLVPVP	KBTBD6	301	Q86V97
RELLFLGPVGLIMYL	AGPAT2	121	O15120
ARPMYILLGVLSFLD	OR10G2	61	Q8NGC3
LQEVPLRYLLGMLYI	UTP20	716	O75691
RAGYRLPLAYFLVGM	TMC3	221	Q7Z5M5
TPKLELLGGAMYYLE	PKHD1	441	P08F94
LRPLLDVYYLPLTNM	STXBP5	976	Q5T5C0
YVPGLLLSYLMLVTV	RETREG3	186	Q86VR2
VQYYGLVMDLLVLGL	PRPF8	1041	Q6P2Q9
LIGPHYYTMRIRLGL	SLC7A14	536	Q8TBB6
RYPYLMLGDSLVLKQ	POGLUT3	381	Q7Z4H8
PRSYLLLLYFMPLAL	PIGZ	366	Q86VD9
LGLTMQYPEGYLEAL	UHRF1	601	Q96T88
RIMQLGIALYYGEIG	VPS13B	276	Q7Z7G8
PIRLMLRLGAEYRLY	ZFYVE9	1071	O95405
GLLPYLMALDQYQLE	NLRP13	16	Q86W25