Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnodal binding

CFC1B CFC1

5.05e-06892GO:0038100
GeneOntologyMolecularFunctionactivin receptor binding

CFC1B CFC1

1.64e-051492GO:0070697
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase binding

CFC1B CFC1

6.30e-052792GO:0070696
GeneOntologyMolecularFunctionreceptor serine/threonine kinase binding

CFC1B CFC1

1.07e-043592GO:0033612
GeneOntologyMolecularFunctioncalcium ion binding

NELL2 LRP2 OC90 NID2

2.13e-0474994GO:0005509
GeneOntologyBiologicalProcessleft lung morphogenesis

CFC1B CFC1

1.02e-06492GO:0060460
GeneOntologyBiologicalProcessleft lung development

CFC1B CFC1

1.69e-06592GO:0060459
GeneOntologyBiologicalProcesscoronary vasculature development

CFC1B LRP2 CFC1

5.19e-068393GO:0060976
GeneOntologyBiologicalProcesscardiac septum morphogenesis

CFC1B LRP2 CFC1

6.40e-068993GO:0060411
GeneOntologyBiologicalProcesscardiac septum development

CFC1B LRP2 CFC1

2.19e-0513493GO:0003279
GeneOntologyBiologicalProcessatrial septum morphogenesis

CFC1B CFC1

2.58e-051892GO:0060413
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

CFC1B LRP2 CFC1

3.79e-0516193GO:0003206
GeneOntologyBiologicalProcessatrial septum development

CFC1B CFC1

5.05e-052592GO:0003283
GeneOntologyBiologicalProcessnodal signaling pathway

CFC1B CFC1

5.47e-052692GO:0038092
GeneOntologyBiologicalProcesscardiac chamber development

CFC1B LRP2 CFC1

8.59e-0521293GO:0003205
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

CFC1B CFC1

1.00e-043592GO:0003209
GeneOntologyBiologicalProcesscardiac atrium development

CFC1B CFC1

1.44e-044292GO:0003230
GeneOntologyBiologicalProcessspleen development

CFC1B CFC1

2.22e-045292GO:0048536
GeneOntologyBiologicalProcessdigestive tract morphogenesis

CFC1B CFC1

2.86e-045992GO:0048546
GeneOntologyBiologicalProcessheart morphogenesis

CFC1B LRP2 CFC1

2.93e-0432193GO:0003007
GeneOntologyBiologicalProcessactivin receptor signaling pathway

CFC1B CFC1

2.96e-046092GO:0032924
GeneOntologyBiologicalProcessheart looping

CFC1B CFC1

4.38e-047392GO:0001947
GeneOntologyBiologicalProcesslung morphogenesis

CFC1B CFC1

4.87e-047792GO:0060425
GeneOntologyBiologicalProcessdetermination of heart left/right asymmetry

CFC1B CFC1

5.12e-047992GO:0061371
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

CFC1B CFC1

5.25e-048092GO:0003143
GeneOntologyBiologicalProcessendoderm development

CFC1B CFC1

6.35e-048892GO:0007492
GeneOntologyBiologicalProcessepithelial tube morphogenesis

CFC1B LRP2 CFC1

6.47e-0442193GO:0060562
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

CFC1B LRP2 CFC1

7.61e-0444593GO:0141091
GeneOntologyBiologicalProcessembryonic heart tube development

CFC1B CFC1

8.69e-0410392GO:0035050
GeneOntologyBiologicalProcessregionalization

CFC1B LRP2 CFC1

9.36e-0447893GO:0003002
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

CFC1B LRP2 CFC1

9.59e-0448293GO:0007178
GeneOntologyBiologicalProcesspattern specification process

CFC1B LRP2 CFC1

1.24e-0352693GO:0007389
GeneOntologyBiologicalProcesshematopoietic or lymphoid organ development

CFC1B CFC1

1.44e-0313392GO:0048534
GeneOntologyBiologicalProcesspost-embryonic development

CFC1B CFC1

1.49e-0313592GO:0009791
GeneOntologyBiologicalProcessdigestive tract development

CFC1B CFC1

1.88e-0315292GO:0048565
GeneOntologyBiologicalProcessdetermination of left/right symmetry

CFC1B CFC1

1.93e-0315492GO:0007368
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

CFC1B LRP2 CFC1

1.97e-0361993GO:0002009
GeneOntologyBiologicalProcessleft/right pattern formation

CFC1B CFC1

2.13e-0316292GO:0060972
GeneOntologyBiologicalProcessspecification of symmetry

CFC1B CFC1

2.21e-0316592GO:0009799
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

CFC1B CFC1

2.21e-0316592GO:0009855
GeneOntologyBiologicalProcessdigestive system development

CFC1B CFC1

2.26e-0316792GO:0055123
GeneOntologyBiologicalProcessembryonic morphogenesis

CFC1B LRP2 CFC1

2.96e-0371393GO:0048598
GeneOntologyBiologicalProcessliver development

CFC1B CFC1

3.28e-0320292GO:0001889
GeneOntologyBiologicalProcesshepaticobiliary system development

CFC1B CFC1

3.38e-0320592GO:0061008
GeneOntologyBiologicalProcesstissue morphogenesis

CFC1B LRP2 CFC1

3.41e-0375093GO:0048729
GeneOntologyBiologicalProcessheart development

CFC1B LRP2 CFC1

3.50e-0375793GO:0007507
GeneOntologyBiologicalProcessgastrulation

CFC1B CFC1

3.61e-0321292GO:0007369
GeneOntologyBiologicalProcessanterior/posterior pattern specification

CFC1B CFC1

4.86e-0324792GO:0009952
GeneOntologyBiologicalProcessimmune system development

CFC1B CFC1

4.90e-0324892GO:0002520
GeneOntologyBiologicalProcesslung development

CFC1B CFC1

5.74e-0326992GO:0030324
GeneOntologyBiologicalProcessrespiratory tube development

CFC1B CFC1

5.91e-0327392GO:0030323
GeneOntologyBiologicalProcessblood vessel development

CFC1B LRP2 CFC1

6.24e-0392993GO:0001568
GeneOntologyBiologicalProcessaxon guidance

NELL2 LRP2

6.42e-0328592GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

NELL2 LRP2

6.47e-0328692GO:0097485
GeneOntologyBiologicalProcessvasculature development

CFC1B LRP2 CFC1

7.02e-0396993GO:0001944
GeneOntologyBiologicalProcessrespiratory system development

CFC1B CFC1

7.33e-0330592GO:0060541
GeneOntologyBiologicalProcesspositive regulation of protein transport

LRP2 MALRD1

7.99e-0331992GO:0051222
GeneOntologyBiologicalProcesspositive regulation of transport

NELL2 LRP2 MALRD1

9.50e-03108193GO:0051050
GeneOntologyBiologicalProcessembryonic organ morphogenesis

CFC1B CFC1

9.61e-0335192GO:0048562
GeneOntologyBiologicalProcesstube morphogenesis

CFC1B LRP2 CFC1

1.06e-02112593GO:0035239
GeneOntologyBiologicalProcesssteroid metabolic process

LRP2 MALRD1

1.10e-0237692GO:0008202
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

CFC1B LRP2 CFC1

1.23e-02118693GO:0007167
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

LRP2 MALRD1

1.25e-0240392GO:1904951
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

NELL2 MALRD1

1.26e-0240492GO:1903532
GeneOntologyCellularComponentcell surface

CFC1B LRP2 NID2 CFC1

8.06e-04111194GO:0009986
HumanPhenoIntestinal malrotation

LRP2 CFC1

9.44e-0415722HP:0002566
MousePhenototal anomalous pulmonary venous connection, intracardiac

CFC1B CFC1

2.87e-07282MP:0010443
MousePhenovascular ring

CFC1B LRP2 CFC1

7.98e-073583MP:0010466
MousePhenototal anomalous pulmonary venous connection

CFC1B CFC1

1.72e-06482MP:0010441
MousePhenounbalanced complete common atrioventricular canal

CFC1B CFC1

1.72e-06482MP:0011673
MousePhenoright aortic arch

CFC1B LRP2 CFC1

4.15e-066083MP:0004158
MousePhenosuperior-inferior ventricles

CFC1B CFC1

6.01e-06782MP:0011254
MousePhenomuscular ventricular septal defect

CFC1B LRP2 CFC1

8.82e-067783MP:0010420
MousePhenoabnormal heart right ventricle size

CFC1B LRP2 CFC1

9.17e-067883MP:0010577
MousePhenoabnormal interventricular septum muscular part morphology

CFC1B LRP2 CFC1

9.53e-067983MP:0010498
MousePhenoaccessory spleen

CFC1B CFC1

1.03e-05982MP:0003342
MousePhenoabnormal truncus arteriosus septation

CFC1B LRP2 CFC1

1.15e-058483MP:0010454
MousePhenod-loop transposition of the great arteries

CFC1B CFC1

2.23e-051382MP:0011665
MousePhenoabnormal direction of embryo turning

CFC1B CFC1

2.23e-051382MP:0004190
MousePhenoheart right ventricle hypoplasia

CFC1B CFC1

2.60e-051482MP:0010422
MousePhenoanomalous pulmonary venous connection

CFC1B CFC1

3.00e-051582MP:0010440
MousePhenoabnormal aortic arch morphology

CFC1B LRP2 CFC1

3.27e-0511983MP:0004113
MousePhenoabnormal thoracic aorta morphology

CFC1B LRP2 CFC1

4.66e-0513483MP:0010468
MousePhenoabnormal cardiac outflow tract development

CFC1B LRP2 CFC1

4.66e-0513483MP:0006126
MousePhenomesocardia

CFC1B CFC1

5.42e-052082MP:0000650
MousePhenoabnormal azygos vein morphology

CFC1B CFC1

5.42e-052082MP:0011569
MousePhenoabnormal heart right ventricle morphology

CFC1B LRP2 CFC1

7.33e-0515683MP:0003920
MousePhenocommon atrium

CFC1B CFC1

7.86e-052482MP:0010406
MousePhenoright pulmonary isomerism

CFC1B CFC1

8.54e-052582MP:0000531
MousePhenodecreased heart right ventricle size

CFC1B CFC1

8.54e-052582MP:0003649
MousePhenocomplete atrioventricular septal defect

CFC1B CFC1

9.25e-052682MP:0010413
MousePhenoabnormal left lung morphology

CFC1B CFC1

1.08e-042882MP:0009569
MousePhenoabsent spleen

CFC1B CFC1

1.15e-042982MP:0000690
MousePhenoright-sided isomerism

CFC1B CFC1

1.24e-043082MP:0000508
MousePhenoright-sided stomach

CFC1B CFC1

1.32e-043182MP:0010808
MousePhenoleft-sided isomerism

CFC1B CFC1

1.59e-043482MP:0000542
MousePhenoabnormal heart and great artery attachment

CFC1B LRP2 CFC1

1.65e-0420583MP:0010426
MousePhenoabnormal heart and great vessel attachment

CFC1B LRP2 CFC1

1.72e-0420883MP:0010425
MousePhenoabnormal stomach position or orientation

CFC1B CFC1

1.79e-043682MP:0010807
MousePhenoabnormal direction of heart looping

CFC1B CFC1

1.99e-043882MP:0004252
MousePhenoabnormal aorta morphology

CFC1B LRP2 CFC1

2.17e-0422583MP:0000272
MousePhenoabnormal right subclavian artery morphology

CFC1B CFC1

2.21e-044082MP:0010487
MousePhenoabnormal heart ventricle size

CFC1B LRP2 CFC1

2.26e-0422883MP:0031543
MousePhenotransposition of great arteries

CFC1B CFC1

3.06e-044782MP:0004110
MousePhenoventricular septal defect

CFC1B LRP2 CFC1

3.36e-0426183MP:0010402
MousePhenodextrocardia

CFC1B CFC1

3.60e-045182MP:0000644
MousePhenodecreased heart ventricle size

CFC1B CFC1

4.04e-045482MP:0031544
MousePhenoabnormal subclavian artery morphology

CFC1B CFC1

4.35e-045682MP:0003395
MousePhenoabnormal digestive organ placement

CFC1B CFC1

4.50e-045782MP:0003283
MousePhenoabnormal lung position or orientation

CFC1B CFC1

4.50e-045782MP:0010853
MousePhenositus inversus

CFC1B CFC1

4.99e-046082MP:0002766
MousePhenoabnormal systemic artery morphology

CFC1B LRP2 CFC1

5.26e-0430483MP:0011655
MousePhenoabnormal left-right axis patterning

CFC1B CFC1

6.22e-046782MP:0001706
MousePhenoabnormal inferior vena cava morphology

CFC1B CFC1

6.41e-046882MP:0006063
MousePhenoabnormal interventricular septum morphology

CFC1B LRP2 CFC1

7.42e-0434283MP:0000281
MousePhenoabnormal heart position or orientation

CFC1B CFC1

7.58e-047482MP:0006065
MousePhenoabnormal vena cava morphology

CFC1B CFC1

8.21e-047782MP:0006062
MousePhenoatrioventricular septal defect

CFC1B CFC1

9.76e-048482MP:0010412
MousePhenoabnormal atrioventricular septum morphology

CFC1B CFC1

1.05e-038782MP:0010592
MousePhenoatrial septal defect

CFC1B CFC1

1.07e-038882MP:0010403
MousePhenoabnormal heart septum morphology

CFC1B LRP2 CFC1

1.07e-0338883MP:0006113
MousePhenoheterotaxia

CFC1B CFC1

1.12e-039082MP:0004133
MousePhenoventricular hypoplasia

CFC1B CFC1

1.35e-039982MP:0000279
MousePhenoabnormal artery morphology

CFC1B LRP2 CFC1

1.54e-0344083MP:0002191
MousePhenoabnormal interatrial septum morphology

CFC1B CFC1

1.58e-0310782MP:0000282
MousePhenospleen hypoplasia

CFC1B CFC1

2.25e-0312882MP:0000694
MousePhenoabnormal heart looping

CFC1B CFC1

2.50e-0313582MP:0000269
MousePhenodouble outlet right ventricle

CFC1B CFC1

3.07e-0315082MP:0000284
MousePhenoabnormal vein morphology

CFC1B CFC1

4.20e-0317682MP:0002725
MousePhenoabnormal heart atrium morphology

CFC1B CFC1

7.19e-0323282MP:0003105
MousePhenoabnormal cochlear labyrinth morphology

LRP2 OC90

7.37e-0323582MP:0004426
MousePhenoabnormal scala media morphology

LRP2 OC90

7.37e-0323582MP:0003169
MousePhenoabnormal lung morphology

CFC1B LRP2 CFC1

7.48e-0376783MP:0001175
MousePhenoanophthalmia

LRP2 MALRD1

8.05e-0324682MP:0001293
MousePhenoabnormal stomach morphology

CFC1B CFC1

8.18e-0324882MP:0000470
MousePhenoabnormal cochlea morphology

LRP2 OC90

8.18e-0324882MP:0000031
MousePhenoabnormal heart ventricle morphology

CFC1B LRP2 CFC1

8.21e-0379383MP:0005294
MousePhenoabnormal embryo turning

CFC1B CFC1

8.37e-0325182MP:0001700
MousePhenoabnormal cardiovascular development

CFC1B LRP2 CFC1

8.48e-0380283MP:0002925
MousePhenoabnormal membranous labyrinth morphology

LRP2 OC90

9.09e-0326282MP:0000035
DomainEGF

NELL2 CFC1B LRP2 MALRD1 NID2 CFC1

1.02e-1023586SM00181
DomainEGF_3

NELL2 CFC1B LRP2 MALRD1 NID2 CFC1

1.02e-1023586PS50026
DomainEGF-like_dom

NELL2 CFC1B LRP2 MALRD1 NID2 CFC1

1.45e-1024986IPR000742
DomainEGF-like_CS

NELL2 CFC1B LRP2 MALRD1 NID2 CFC1

1.92e-1026186IPR013032
DomainEGF_2

NELL2 CFC1B LRP2 MALRD1 NID2 CFC1

2.11e-1026586PS01186
DomainEGF_1

NELL2 CFC1B LRP2 MALRD1 CFC1

2.47e-0825585PS00022
DomainCFC

CFC1B CFC1

4.82e-07382PF09443
DomainCryptic/Cripto_CFC-dom

CFC1B CFC1

4.82e-07382IPR019011
DomainEGF_CA

NELL2 LRP2 NID2

5.19e-068683PF07645
DomainEGF_Ca-bd_CS

NELL2 LRP2 NID2

7.46e-069783IPR018097
DomainEGF_CA

NELL2 LRP2 NID2

7.94e-069983PS01187
DomainASX_HYDROXYL

NELL2 LRP2 NID2

8.18e-0610083PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL2 LRP2 NID2

9.75e-0610683IPR000152
DomainLdl_recept_b

LRP2 NID2

1.46e-051482PF00058
DomainLDLRB

LRP2 NID2

1.46e-051482PS51120
DomainEGF_CA

NELL2 LRP2 NID2

1.49e-0512283SM00179
DomainEGF-like_Ca-bd_dom

NELL2 LRP2 NID2

1.56e-0512483IPR001881
DomainEGF

LRP2 MALRD1 NID2

1.64e-0512683PF00008
DomainLY

LRP2 NID2

1.68e-051582SM00135
DomainLDLR_classB_rpt

LRP2 NID2

1.68e-051582IPR000033
DomainGrowth_fac_rcpt_

NELL2 LRP2 NID2

3.10e-0515683IPR009030
DomaincEGF

LRP2 NID2

5.19e-052682PF12662
DomaincEGF

LRP2 NID2

5.19e-052682IPR026823
Domain-

LRP2 NID2

1.18e-0439822.120.10.30
DomainLDLR_class-A_CS

LRP2 MALRD1

1.24e-044082IPR023415
DomainLdl_recept_a

LRP2 MALRD1

1.57e-044582PF00057
Domain-

LRP2 MALRD1

1.65e-0446824.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP2 NID2

1.65e-044682IPR011042
DomainLDLRA_1

LRP2 MALRD1

1.79e-044882PS01209
DomainLDLa

LRP2 MALRD1

1.87e-044982SM00192
DomainLDLRA_2

LRP2 MALRD1

1.87e-044982PS50068
DomainLDrepeatLR_classA_rpt

LRP2 MALRD1

1.87e-044982IPR002172
DomainEGF_extracell

NELL2 LRP2

2.81e-046082IPR013111
DomainEGF_2

NELL2 LRP2

2.81e-046082PF07974
DomainConA-like_dom

NELL2 MALRD1

3.66e-0321982IPR013320
PathwayWP_MIR127_IN_MESENDODERM_DIFFERENTIATION

CFC1B CFC1

6.63e-061252MM15910
Pubmed

Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.

CFC1B CFC1

5.95e-0829211327798
Pubmed

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

CFC1B CFC1

5.95e-0829211062482
Pubmed

Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.

CFC1B CFC1

5.95e-0829211024280
Pubmed

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

CFC1B CFC1

5.95e-0829211174844
Pubmed

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.

CFC1B CFC1

1.79e-0739216835440
Pubmed

Role of the EGF-CFC gene cripto in cell differentiation and embryo development.

CFC1B CFC1

3.57e-0749211992720
Pubmed

Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.

CFC1B CFC1

3.57e-074929576836
Pubmed

Cripto in tumors and embryo development.

CFC1B CFC1

3.57e-0749211825688
Pubmed

Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.

CFC1B CFC1

5.95e-0759225224222
Pubmed

A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.

CFC1B CFC1

5.95e-075929053319
Pubmed

A role of the cryptic gene in the correct establishment of the left-right axis.

CFC1B CFC1

8.92e-0769210574770
Pubmed

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.

CFC1B CFC1

8.92e-0769212052855
Pubmed

GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.

CFC1B CFC1

8.92e-0769217991893
Pubmed

Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.

CFC1B CFC1

1.25e-0679219906859
Pubmed

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.

CFC1B CFC1

1.25e-0679210521397
Pubmed

Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.

CFC1B CFC1

1.67e-0689221419113
Pubmed

Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.

CFC1B CFC1

1.67e-0689215736223
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

CFC1B LRP2 CFC1

1.91e-061009325807483
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP2 NID2

2.14e-0699210772929
Pubmed

Left-right patterning of the mouse lateral plate requires nodal produced in the node.

CFC1B CFC1

2.14e-0699212654299
Pubmed

Left-asymmetric expression of Galanin in the linear heart tube of the mouse embryo is independent of the nodal co-receptor gene cryptic.

CFC1B CFC1

2.14e-0699218773496
Pubmed

Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.

CFC1B CFC1

2.68e-06109217913787
Pubmed

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway.

CFC1B CFC1

3.27e-06119215475956
Pubmed

BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment.

CFC1B CFC1

4.64e-06139218550712
Pubmed

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.

CFC1B CFC1

5.41e-06149217210915
Pubmed

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells.

CFC1B CFC1

6.24e-06159217360443
Pubmed

Rab23 regulates Nodal signaling in vertebrate left-right patterning independently of the Hedgehog pathway.

CFC1B CFC1

6.24e-06159224780629
Pubmed

Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse.

CFC1B CFC1

6.24e-06159212361961
Pubmed

Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature.

CFC1B CFC1

6.24e-06159233730615
Pubmed

Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.

CFC1B CFC1

8.08e-06179218697220
Pubmed

Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate.

CFC1B CFC1

8.08e-06179219716815
Pubmed

Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo.

CFC1B CFC1

8.08e-06179222627279
Pubmed

Tcf3: a transcriptional regulator of axis induction in the early embryo.

CFC1B CFC1

9.09e-06189214668413
Pubmed

Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.

CFC1B CFC1

9.09e-06189220346354
Pubmed

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.

CFC1B CFC1

9.09e-06189217936261
Pubmed

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.

CFC1B CFC1

1.02e-05199228126904
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node.

CFC1B CFC1

1.13e-05209211440720
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node.

CFC1B CFC1

1.13e-05209211517919
Pubmed

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.

CFC1B CFC1

1.25e-05219216291790
Pubmed

Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo.

CFC1B CFC1

1.37e-05229218241853
Pubmed

Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.

CFC1B CFC1

1.50e-05239214623818
Pubmed

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.

CFC1B CFC1

1.64e-05249218171685
Pubmed

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.

CFC1B CFC1

1.93e-05269223034635
Pubmed

The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo.

CFC1B CFC1

1.93e-05269223651855
Pubmed

Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast.

CFC1B CFC1

2.24e-05289211412024
Pubmed

Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.

CFC1B CFC1

3.73e-05369227606604
InteractionZNF101 interactions

NELL2 OC90

7.24e-053382int:ZNF101
InteractionCCN3 interactions

NID2 C11orf87

9.62e-053882int:CCN3
InteractionZFP41 interactions

NELL2 LRP2

2.18e-045782int:ZFP41
InteractionPLAU interactions

LRP2 CFC1

2.25e-045882int:PLAU
InteractionLGALS1 interactions

LRP2 NID2 C11orf87

2.33e-0433283int:LGALS1
InteractionLTBP4 interactions

NELL2 CFC1

3.01e-046782int:LTBP4
InteractionFBXO2 interactions

NELL2 LRP2 NID2

4.37e-0441183int:FBXO2
InteractionMDK interactions

LRP2 NID2

5.55e-049182int:MDK
InteractionTRIM33 interactions

NELL2 LRP2 NID2

5.81e-0445383int:TRIM33
InteractionMATN2 interactions

NELL2 NID2

8.54e-0411382int:MATN2
InteractionLAMA5 interactions

NID2 CFC1

9.15e-0411782int:LAMA5
InteractionLAMB2 interactions

NID2 CFC1

9.94e-0412282int:LAMB2
InteractionTHBS1 interactions

LRP2 CFC1

1.08e-0312782int:THBS1
InteractionLAMC1 interactions

NID2 CFC1

1.21e-0313582int:LAMC1
InteractionLAMB1 interactions

NID2 CFC1

1.34e-0314282int:LAMB1
InteractionSLURP1 interactions

NELL2 NID2

1.38e-0314482int:SLURP1
InteractionZNF408 interactions

NELL2 LRP2

1.40e-0314582int:ZNF408
Cytoband2q21.1

CFC1B CFC1

5.61e-0558922q21.1
CytobandEnsembl 112 genes in cytogenetic band chr2q21

CFC1B CFC1

3.81e-0415192chr2q21
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_EARLY_MESOTHELIAL_CELL

NELL2 CFC1B LRP2 CFC1

2.81e-0558494M45668
CoexpressionMIKKELSEN_MEF_ICP_WITH_H3K27ME3

CFC1B CFC1 C11orf87

4.91e-0522393MM838
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A

CFC1B LRP2 OC90 CFC1

1.72e-0493094MM893
CoexpressionNABA_MATRISOME

NELL2 CFC1B NID2 CFC1

2.35e-04100894MM17056
CoexpressionNABA_MATRISOME

NELL2 CFC1B NID2 CFC1

2.51e-04102694M5889
CoexpressionAtlasEB blastocyst_vs_EB UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05

CFC1B NID2 CFC1

2.49e-066793PCBC_ratio_EB blastocyst_vs_EB UCB CD34+Z_cfr-2X-p05
CoexpressionAtlasMESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst-Confounder_removed-fold2.0_adjp0.05

NELL2 CFC1B ZDBF2 CFC1

1.72e-0541894PCBC_ratio_MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst_cfr-2X-p05
CoexpressionAtlasEmbryoid Body Cells-method_NA_vs_Embryoid Body Cells-method_plasmid-Confounder_removed-fold2.0_adjp0.05

CFC1B CFC1

4.39e-052492PCBC_ratio_EB_from-ESC_vs_EB_from-plasmid_cfr-2X-p05
CoexpressionAtlasEB blastocyst_vs_EB cord blood-Confounder_removed-fold2.0_adjp0.05

CFC1B CFC1

1.17e-043992PCBC_ratio_EB blastocyst_vs_EB cord blood_cfr-2X-p05
CoexpressionAtlasEB blastocyst_vs_EB amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05

CFC1B NID2 CFC1

2.20e-0430093PCBC_ratio_EB blastocyst_vs_EB amniotic fluid MSC_cfr-2X-p05
CoexpressionAtlasBM Top 100 - frontal lobe

NELL2 C11orf87

4.02e-047292BM Top 100 - frontal lobe
CoexpressionAtlasBM Top 100 - thyroid gland

LRP2 NID2

4.13e-047392BM Top 100 - thyroid gland
CoexpressionAtlasEctoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

NELL2 ZDBF2 LRP2 NID2

4.48e-0496794PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasBM Top 100 - hippocampus

NELL2 C11orf87

4.72e-047892BM Top 100 - hippocampus
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

NELL2 ZDBF2 LRP2 C11orf87

4.77e-0498394Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

NELL2 ZDBF2 LRP2 NID2

6.71e-04107594PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_100

LRP2 C11orf87

7.58e-049992Facebase_RNAseq_e8.5_Floor Plate_100
CoexpressionAtlasEmbryoid Body Cells-reprogram_NA_vs_Embryoid Body Cells-reprogram_OSKM-L-Confounder_removed-fold2.0_adjp0.05

CFC1B CFC1

8.05e-0410292PCBC_ratio_EB_from-ESC_vs_EB_from-OSKM-L_cfr-2X-p05
CoexpressionAtlasEmbryoid Body Cells-method_NA_vs_Embryoid Body Cells-method_mRNA-Confounder_removed-fold2.0_adjp0.05

CFC1B CFC1

8.05e-0410292PCBC_ratio_EB_from-ESC_vs_EB_from-mRNA_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500

NELL2 ZDBF2 LRP2

8.82e-0448293Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

NELL2 ZDBF2 C11orf87

9.41e-0449393Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500

ZDBF2 LRP2 C11orf87

9.53e-0449593Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500

NELL2 LRP2 CFC1

9.58e-0449693PCBC_EB_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

NELL2 LRP2 CFC1

9.58e-0449693PCBC_EB_blastocyst_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500

NELL2 ZDBF2 LRP2

9.58e-0449693Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

NELL2 ZDBF2 LRP2

9.69e-0449893Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#2_top-relative-expression-ranked_500

NID2 C11orf87

1.28e-0312992gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#4

NELL2 ZDBF2

1.44e-0313792Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NELL2 LRP2 CFC1

5.92e-06188939655a4c47b644a870017d349b99063e17dbae572
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NELL2 NID2

8.53e-057092aa63c1b77a9fb15e75835cb3781f2d890f3fe328
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

NELL2 CFC1

3.61e-0414492e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 C11orf87

4.07e-0415392489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

NELL2 ZDBF2

4.45e-0416092a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

NELL2 ZDBF2

4.51e-041619282196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 NID2

4.85e-0416792351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 NID2

4.85e-0416792c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

NELL2 LRP2

4.85e-0416792892a2dc83ab5de5a1016402f8e95d2aabf651326
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 MALRD1

4.90e-0416892ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 NID2

4.90e-0416892a086c306be430adf0632ba53e98cd8014d2de330
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 MALRD1

4.90e-04168924e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

4.96e-04169920cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

4.96e-04169926937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 NID2

5.14e-041729236a96714a0eb6ac438648135336c9791881ddadb
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NELL2 NID2

5.14e-04172928d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NELL2 NID2

5.20e-0417392ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NELL2 NID2

5.20e-04173923725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 C11orf87

5.38e-04176928b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL2 C11orf87

5.44e-04177929ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL2 C11orf87

5.44e-0417792016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFC1B CFC1

5.44e-04177920912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 LRP2

5.50e-0417892d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NID2 C11orf87

5.56e-041799210fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellwk_15-18-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NELL2 CFC1

5.56e-0417992b1f085e4c8d65d5cdbfaf2db80343638abb08979
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.56e-0417992056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 LRP2

5.56e-04179924135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.56e-0417992f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZDBF2 LRP2

5.56e-0417992bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.69e-04181923dcb74b28f93be35ddf4de1937f7e30b25e11927
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 NID2

5.69e-04181926956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.69e-04181927679a5980011d6dfb1aaca7abf678c29b6f819bb
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.81e-0418392c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

5.81e-04183929d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL2 MALRD1

5.81e-0418392274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 C11orf87

5.88e-04184927aa245b73e10fd73d292e822de6b72920aa12355
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NELL2 CFC1

5.94e-0418592492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 C11orf87

6.07e-041879208c73d125e0638c9e9878165bba2442c266c8a48
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 C11orf87

6.07e-0418792f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 C11orf87

6.07e-041879202e7246ef5ad41773d14426254e139b156d45c1d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

6.13e-041889200c5259bcb83218b7d44f4d585d9b68ef49763ab
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZDBF2 C11orf87

6.26e-0419092416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZDBF2 C11orf87

6.33e-041919273dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NELL2 NID2

6.33e-0419192156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZDBF2 C11orf87

6.33e-04191925d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CFC1

6.33e-04191924c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZDBF2 C11orf87

6.39e-04192924c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellmild_COVID-19_(asymptomatic)-CD4+_Tcm|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

NELL2 ZDBF2

6.46e-0419392498d3a83bce6deff69aea71b18a43688e0a8ed7d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 C11orf87

6.46e-041939247d189bac0ef4df2f5c6dd987e46aca85bd7e2af
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

6.59e-04195928a9d05f7a5397836b7dfb8ae4f7c4896042ac0fe
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL2 C11orf87

6.59e-0419592787e95fb59c40bba784544b662fac37606ae1427
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 C11orf87

6.59e-0419592ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

6.66e-0419692ee89f6884aea11aefeaabe043db7f80145dcdf7f
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

6.66e-0419692147dc1ca5942df48a083cce39a9a7541430f8365
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 CFC1

6.66e-0419692e75c36cb042342d69a593fb1ce62fab033889871
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 C11orf87

6.73e-041979227c044833e471a312a572e0b1c83e4bc8a36e896
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NID2 CFC1

6.80e-04198921282db321e27499d310339d6383974614e295a20
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NELL2 NID2

6.80e-0419892d1827e3707b929e3a3562989a0c11537d344e164
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm|Leuk-UTI / Disease, condition lineage and cell class

NELL2 NID2

6.87e-04199926a1d84f61e1efaab541910926d6911122372659f
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_T_naive|Int-URO / Disease, condition lineage and cell class

NELL2 NID2

6.93e-0420092a4b531355e87efd6b69a16eeec8b1ff14c7af750
Diseasedouble outlet right ventricle (implicated_via_orthology)

CFC1B CFC1

2.48e-07392DOID:6406 (implicated_via_orthology)
Diseaseright atrial isomerism (implicated_via_orthology)

CFC1B CFC1

4.96e-07492DOID:0060856 (implicated_via_orthology)
Diseasedextro-looped transposition of the great arteries (implicated_via_orthology)

CFC1B CFC1

4.96e-07492DOID:0060770 (implicated_via_orthology)
Diseasevisceral heterotaxy (is_implicated_in)

CFC1B CFC1

5.45e-061292DOID:0050545 (is_implicated_in)
Diseasevisceral heterotaxy (implicated_via_orthology)

CFC1B CFC1

5.48e-053792DOID:0050545 (implicated_via_orthology)
Diseaseamino acid measurement

NELL2 LRP2

1.71e-0267892EFO_0005134
Diseaseurate measurement

LRP2 MALRD1

2.87e-0289592EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
GRYCEHDQRRSECGA

CFC1B

111

P0CG36
GRYCEHDQRRSECGA

CFC1

111

P0CG37
IDECAEGRHYCRENT

NELL2

441

Q99435
RCDRHNDCGDYSDER

LRP2

3011

P98164
DESDSCCFQHRRCYE

OC90

111

Q02509
RCECRSGYEFADDRH

NID2

826

Q14112
SSDERHCLNYERCDF

MALRD1

61

Q5VYJ5
RAQEEYERDHCSGSR

C11orf87

96

Q6NUJ2
REGRFHCYFDDDCET

ZDBF2

1851

Q9HCK1