Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cellular component maintenance	CNTNAP1 GRN NLGN1 TREM2 PLXNA4 PLEKHA7	2.17e-05	101	115	6	GO:0043954
GeneOntologyBiologicalProcess	cell junction maintenance	CNTNAP1 GRN NLGN1 PLXNA4 PLEKHA7	3.12e-05	65	115	5	GO:0034331
GeneOntologyCellularComponent	asymmetric, glutamatergic, excitatory synapse	OGT GRN NLGN1 PLXNA4	9.71e-06	24	119	4	GO:0098985
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	9.30e-07	4	116	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	9.30e-07	4	116	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	9.30e-07	4	116	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	9.30e-07	4	116	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	9.30e-07	4	116	3	IPR015753
Domain	FA58C	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	7.79e-06	21	116	4	SM00231
Domain	FA58C_3	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	7.79e-06	21	116	4	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	7.79e-06	21	116	4	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	7.79e-06	21	116	4	PS01286
Domain	Calx_beta	ADGRV1 FREM3 SLC8A1	1.28e-05	8	116	3	SM00237
Domain	F5_F8_type_C	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	1.36e-05	24	116	4	PF00754
Domain	FA58C	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	1.36e-05	24	116	4	IPR000421
Domain	Calx_beta	ADGRV1 FREM3 SLC8A1	1.91e-05	9	116	3	IPR003644
Domain	Calx-beta	ADGRV1 FREM3 SLC8A1	1.91e-05	9	116	3	PF03160
Domain	FIBRINOGEN_C_1	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	4.44e-05	32	116	4	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	4.44e-05	32	116	4	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	4.44e-05	32	116	4	PS51406
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	8.86e-05	38	116	4	PS50025
Domain	Laminin_G_2	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	1.09e-04	40	116	4	PF02210
Domain	LamG	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	1.58e-04	44	116	4	SM00282
Domain	-	LGALS9B CNTNAP1 CNTNAP3 ADGRV1 CNTNAP4	3.15e-04	95	116	5	2.60.120.200
Domain	Laminin_G	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	4.63e-04	58	116	4	IPR001791
Domain	S_100	FLG2 RPTN CRNN	6.12e-04	27	116	3	PF01023
Domain	S100_Ca-bd_sub	FLG2 RPTN CRNN	6.83e-04	28	116	3	IPR013787
Domain	S_100	FLG2 RPTN CRNN	6.83e-04	28	116	3	SM01394
Domain	FBG	CNTNAP1 CNTNAP3 CNTNAP4	7.58e-04	29	116	3	SM00186
Domain	-	CNTNAP1 CNTNAP3 CNTNAP4	8.39e-04	30	116	3	3.90.215.10
Domain	Fibrinogen_a/b/g_C_1	CNTNAP1 CNTNAP3 CNTNAP4	8.39e-04	30	116	3	IPR014716
Domain	TIG	PKHD1L1 PLXNA4 CAMTA1	9.24e-04	31	116	3	PF01833
Domain	IPT	PKHD1L1 PLXNA4 CAMTA1	1.02e-03	32	116	3	IPR002909
Domain	Sp1_fam	SP1 SP3	1.67e-03	10	116	2	IPR030450
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	FOXO3 SP1 SP3 ANKFY1 HIVEP1 ZNF148 TFDP3 BRD3 FOXJ3 PKHD1L1 ARFGAP2 TSC22D1 SATB1 BTBD7 GLI3 ARID2 ZFHX3 PBX3	3.32e-10	808	119	18	20412781
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF536 HIVEP1 OGT ZNF148 NUP98 FLG2 KMT2C SATB1 TLE1 ARID2 ZFHX3 QSER1	3.34e-09	351	119	12	38297188
Pubmed	Human transcription factor protein interaction networks.	SP1 ZNF536 MYBBP1A HIVEP1 OGT UBAP2 ZNF148 UBR4 NUP98 GRN FLG2 KMT2C SATB1 TLE1 GLI3 ARID2 TNRC6A ZNF770 ZFHX3 QSER1	8.36e-08	1429	119	20	35140242
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SP1 MYBBP1A HIVEP1 ZNF148 UBR4 SOCS6 KMT2C STARD9 GLI3	1.19e-07	233	119	9	37704626
Pubmed	A human MAP kinase interactome.	SP1 SYNPO2 HIVEP1 NUP98 KMT2C TSC22D1 USF3 ARID2 TNRC6A BICRAL COG5 MAP3K2	1.19e-07	486	119	12	20936779
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SP1 SP3 ZNF536 ANKFY1 HIVEP1 TFDP3 BRD3 FOXJ3 ZFAND4 KMT2C SATB1 GLI3 ZFHX3 PBX3	1.55e-07	709	119	14	22988430
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	1.56e-07	4	119	3	22419166
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 ANKFY1 HIVEP1 OGT ZNF148 UBR4 TFDP3 SATB1 TLE1 TNRC6A ZFHX3	2.19e-07	418	119	11	34709266
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 ZNF536 OGT ZNF148 RNF213 BRD3 SUCLG1 VPS52 SV2A GLI3 ARID2 SCN5A TNRC6A CRNN ZFHX3 BICRAL WWC1	2.70e-07	1116	119	17	31753913
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SP1 SP3 SYNPO2 UBAP2 UBR4 NUP98 FOXJ3 USF3 ARID2 CAMTA1 PLEKHA7	2.90e-07	430	119	11	35044719
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TANC2 SP1 ATP13A4 ZNF536 ANKFY1 HIVEP1 LRRC37A3 UBR4 FOXJ3 ZFAND4 ARID2 MIB1 FER1L5	3.12e-07	638	119	13	31182584
Pubmed	ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1.	SP1 SP3 ZNF148	3.89e-07	5	119	3	12771217
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXO3 SP1 SP3 HIVEP1 IRX5 ZNF148 TFDP3 FOXJ3 TSC22D1 USF3 SATB1 GLI3 ZFHX3 CAMTA1 PBX3	5.28e-07	908	119	15	19274049
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 FOXO3 HIVEP1 UBAP2 KLHDC2 MPDZ ARFGAP2 DENND1B STARD9 KRT77 PLEKHA7 PLK4 WNK3 MAP3K2	1.56e-06	861	119	14	36931259
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	4.61e-06	10	119	3	23064749
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	HIVEP1 OGT ZNF148 BRD3 FOXJ3 ZNF776 SATB1 ARID2 ZNF770 MPHOSPH8 QSER1	8.17e-06	608	119	11	36089195
Pubmed	High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.	SP1 SP3 OGT	1.09e-05	13	119	3	17670746
Pubmed	Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failure.	SP1 SP3	1.16e-05	2	119	2	10825178
Pubmed	HPV8 activates cellular gene expression mainly through Sp1/3 binding sites.	SP1 SP3	1.16e-05	2	119	2	31299490
Pubmed	CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia.	GRN TREM2	1.16e-05	2	119	2	33896652
Pubmed	Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.	SP1 SP3	1.16e-05	2	119	2	25538045
Pubmed	CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.	GRN TREM2	1.16e-05	2	119	2	30482868
Pubmed	Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors.	SP1 SP3	1.16e-05	2	119	2	31164147
Pubmed	Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus.	SP1 SP3	1.16e-05	2	119	2	17681019
Pubmed	Endothelial Sp1/Sp3 are essential to the effect of captopril on blood pressure in male mice.	SP1 SP3	1.16e-05	2	119	2	37735515
Pubmed	O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions.	SP1 OGT	1.16e-05	2	119	2	9343410
Pubmed	Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.	SP1 SP3	1.16e-05	2	119	2	26807725
Pubmed	Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide.	SP1 SP3	1.16e-05	2	119	2	15951564
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	1.16e-05	2	119	2	26807827
Pubmed	Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene.	SP1 SP3	1.16e-05	2	119	2	22464952
Pubmed	Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.	SP1 SP3	1.16e-05	2	119	2	8845379
Pubmed	Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.	GRN TREM2	1.16e-05	2	119	2	35019161
Pubmed	Expression of the human endogenous retrovirus (HERV) group HML-2/HERV-K does not depend on canonical promoter elements but is regulated by transcription factors Sp1 and Sp3.	SP1 SP3	1.16e-05	2	119	2	21248046
Pubmed	Sp1 and Sp3 activate transcription of the human dopamine transporter gene.	SP1 SP3	1.16e-05	2	119	2	15816870
Pubmed	Sp family transcription factors regulate expression of rat D2 dopamine receptor gene.	SP1 SP3	1.16e-05	2	119	2	9628590
Pubmed	Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.	RPTN CRNN	1.16e-05	2	119	2	28219068
Pubmed	The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells.	SP1 SP3	1.16e-05	2	119	2	14608051
Pubmed	Differentiation-dependent and cell-specific regulation of the hIGFBP-1 gene in human endometrium.	SP1 SP3	1.16e-05	2	119	2	9329821
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	1.16e-05	2	119	2	31150793
Pubmed	Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.	SP1 SP3	1.16e-05	2	119	2	14766015
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	1.16e-05	2	119	2	31400758
Pubmed	Myoepithelioma-like Hyalinizing Epithelioid Tumors of the Hand With Novel OGT-FOXO3 Fusions.	FOXO3 OGT	1.16e-05	2	119	2	31567281
Pubmed	An Sp1/Sp3 binding polymorphism confers methylation protection.	SP1 SP3	1.16e-05	2	119	2	18725933
Pubmed	Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.	SP1 SP3	1.16e-05	2	119	2	19437621
Pubmed	SP1 upregulated FoxO3a promotes tumor progression in colorectal cancer.	FOXO3 SP1	1.16e-05	2	119	2	29565456
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	1.16e-05	2	119	2	37450367
Pubmed	Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.	GRN TREM2	1.16e-05	2	119	2	31122931
Pubmed	Transcriptional control of human CD2AP expression: the role of Sp1 and Sp3.	SP1 SP3	1.16e-05	2	119	2	21604172
Pubmed	Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma.	SP1 WWC1	1.16e-05	2	119	2	29046731
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF536 ANKFY1 NLGN1 DNAJC6 NEGR1 SV2A BTBD7 STARD9 CAMTA1	1.17e-05	407	119	9	12693553
Pubmed	Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.	SLC8A1 CNTNAP4 DNAH9	1.38e-05	14	119	3	24811271
Pubmed	Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.	CNTNAP3B CNTNAP3 CNTNAP4	2.56e-05	17	119	3	26389685
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TANC2 RNF213 ARID2 PLXNA4 WNK3	2.63e-05	101	119	5	10997877
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 DMXL2 MYBBP1A ANKFY1 OGT UBAP2 UBR4 CNTNAP1 MPDZ DNAJC6 DCHS1 QSER1 WNK3	2.71e-05	963	119	13	28671696
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	UBAP2 NLGN1 KMT2C BTBD7 TNRC6A	2.89e-05	103	119	5	10819331
Pubmed	Expression patterns of SP1 and SP3 during mouse spermatogenesis: SP1 down-regulation correlates with two successive promoter changes and translationally compromised transcripts.	SP1 SP3	3.47e-05	3	119	2	18417714
Pubmed	Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.	SP1 SP3	3.47e-05	3	119	2	14701757
Pubmed	Regulation of the human secretin gene is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element.	SP1 SP3	3.47e-05	3	119	2	15118068
Pubmed	Modulation of Bone Morphogenetic Protein (BMP) 2 gene expression by Sp1 transcription factors.	SP1 SP3	3.47e-05	3	119	2	17317039
Pubmed	In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.	SP1 SP3	3.47e-05	3	119	2	11850421
Pubmed	Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.	SP1 SP3	3.47e-05	3	119	2	36759621
Pubmed	Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells.	SP1 SP3	3.47e-05	3	119	2	16529657
Pubmed	Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence.	SP1 SP3	3.47e-05	3	119	2	23028678
Pubmed	Sp proteins and Runx2 mediate regulation of matrix gla protein (MGP) expression by parathyroid hormone.	SP1 SP3	3.47e-05	3	119	2	19306294
Pubmed	Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.	SP1 SP3	3.47e-05	3	119	2	15482850
Pubmed	Structural and functional characterization of the mouse tescalcin promoter.	SP1 SP3	3.47e-05	3	119	2	20540995
Pubmed	Transcriptional regulation of the human CD97 promoter by Sp1/Sp3 in smooth muscle cells.	SP1 SP3	3.47e-05	3	119	2	18329191
Pubmed	Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide.	SP1 SP3	3.47e-05	3	119	2	20974858
Pubmed	Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene.	SP1 SP3	3.47e-05	3	119	2	12799440
Pubmed	Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors.	FOXO3 FOXJ3	3.47e-05	3	119	2	26578569
Pubmed	The constitutive expression of anticoagulant protein S is regulated through multiple binding sites for Sp1 and Sp3 transcription factors in the protein S gene promoter.	SP1 SP3	3.47e-05	3	119	2	16672217
Pubmed	Transcription of the LAT gene is regulated by multiple binding sites for Sp1 and Sp3.	SP1 SP3	3.47e-05	3	119	2	18343609
Pubmed	The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis.	MIB1 PLK4	3.47e-05	3	119	2	25795303
Pubmed	Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.	SP1 SP3	3.47e-05	3	119	2	11532028
Pubmed	Cell confluency-induced Stat3 activation regulates NHE3 expression by recruiting Sp1 and Sp3 to the proximal NHE3 promoter region during epithelial dome formation.	SP1 SP3	3.47e-05	3	119	2	19064501
Pubmed	Sp1 and Sp3 Are important regulators of AP-2gamma gene transcription.	SP1 SP3	3.47e-05	3	119	2	12801994
Pubmed	Functional interplay of SP family members and nuclear factor Y is essential for transcriptional activation of the human Calreticulin gene.	SP1 SP3	3.47e-05	3	119	2	26162987
Pubmed	Sp1 and Sp3 mediate basal and serum-induced expression of human CENP-W.	SP1 SP3	3.47e-05	3	119	2	20180024
Pubmed	Murine glypican-4 gene structure and expression; Sp1 and Sp3 play a major role in glypican-4 expression in 3T3-F442A cells.	SP1 SP3	3.47e-05	3	119	2	15297147
Pubmed	Accessible chromatin structure permits factors Sp1 and Sp3 to regulate human TGFBI gene expression.	SP1 SP3	3.47e-05	3	119	2	21554857
Pubmed	Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase.	SP1 SP3	3.47e-05	3	119	2	15451065
Pubmed	Molecular and functional characterization of the murine ldh2 promoter region: Sp-binding GC-box domains are the key cis-elements regulating ldh2 gene expression during spermatogenesis.	SP1 SP3	3.47e-05	3	119	2	18790003
Pubmed	Transcription of human β4-galactosyltransferase 3 is regulated by differential DNA binding of Sp1/Sp3 in SH-SY5Y human neuroblastoma and A549 human lung cancer cell lines.	SP1 SP3	3.47e-05	3	119	2	30561605
Pubmed	Identification of regulatory elements in the human adipose most abundant gene transcript-1 ( apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways.	SP1 SP3	3.47e-05	3	119	2	12378384
Pubmed	The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid.	SP1 SP3	3.47e-05	3	119	2	15466927
Pubmed	Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements.	SP1 SP3	3.47e-05	3	119	2	12509426
Pubmed	Sp1 and Sp3 transcription factors regulate the basal expression of human microsomal epoxide hydrolase (EPHX1) through interaction with the E1b far upstream promoter.	SP1 SP3	3.47e-05	3	119	2	24315822
Pubmed	Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-gamma/TNF-alpha.	SP1 SP3	3.47e-05	3	119	2	17540780
Pubmed	Regulation of the poly(ADP-ribose) polymerase-1 gene expression by the transcription factors Sp1 and Sp3 is under the influence of cell density in primary cultured cells.	SP1 SP3	3.47e-05	3	119	2	15777284
Pubmed	Differentially expressed genes in endothelial differentiation.	KLHDC2 BRD3	3.47e-05	3	119	2	16008511
Pubmed	The HIV-Tat protein interacts with Sp3 transcription factor and inhibits its binding to a distal site of the sod2 promoter in human pulmonary artery endothelial cells.	SP1 SP3	3.47e-05	3	119	2	31863909
Pubmed	The interaction with Sp1 and reduction in the activity of histone deacetylase 1 are critical for the constitutive gene expression of IL-1 alpha in human melanoma cells.	SP1 SP3	3.47e-05	3	119	2	17906119
Pubmed	HIV-1 Tat regulates the SOD2 basal promoter by altering Sp1/Sp3 binding activity.	SP1 SP3	3.47e-05	3	119	2	15706661
Pubmed	NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes.	SP1 SP3	3.47e-05	3	119	2	16671893
Pubmed	Transcriptional activation of Mina by Sp1/3 factors.	SP1 SP3	3.47e-05	3	119	2	24324617
Pubmed	AhR regulates the expression of human cytochrome P450 1A1 (CYP1A1) by recruiting Sp1.	CYP1A1 SP1	3.47e-05	3	119	2	31199573
Pubmed	Functional characterization of the proximal promoter of the murine pyruvate carboxylase gene in hepatocytes: role of multiple gc boxes.	SP1 SP3	3.47e-05	3	119	2	21745612
Pubmed	Dystrophin Dp71 expression is down-regulated during myogenesis: role of Sp1 and Sp3 on the Dp71 promoter activity.	SP1 SP3	3.47e-05	3	119	2	15550398
Pubmed	Induction of murine H-rev107 gene expression by growth arrest and histone acetylation: involvement of an Sp1/Sp3-binding GC-box.	SP1 SP3	3.47e-05	3	119	2	12054741
Pubmed	COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells.	SP1 SP3	3.47e-05	3	119	2	9388268
Interaction	EGR2 interactions	ZNF536 HIVEP1 ZNF148 FLG2 KMT2C TLE1 ARID2 ZFHX3 QSER1	7.48e-07	171	118	9	int:EGR2
Interaction	TEAD1 interactions	ZNF536 HIVEP1 ZNF148 MPDZ KMT2C SATB1 TLE1 ARID2 ZFHX3	9.52e-07	176	118	9	int:TEAD1
Interaction	GATA2 interactions	ZNF536 HIVEP1 KMT2C SATB1 TLE1 ARID2 TRAPPC10 ZFHX3 QSER1	2.63e-06	199	118	9	int:GATA2
Interaction	EN1 interactions	ZNF536 HIVEP1 ZNF148 KMT2C TLE1 QSER1 PBX3	3.81e-06	110	118	7	int:EN1
Interaction	TBR1 interactions	ZNF536 HIVEP1 BRD3 KMT2C TLE1 ZFHX3 QSER1	4.56e-06	113	118	7	int:TBR1
Interaction	TBXT interactions	ZNF536 HIVEP1 ZNF148 KMT2C SATB1 TLE1 QSER1	5.43e-06	116	118	7	int:TBXT
Interaction	GSC interactions	ZNF536 HIVEP1 KMT2C TLE1 ZFHX3 QSER1	1.22e-05	87	118	6	int:GSC
Interaction	HNF1B interactions	ZNF536 HIVEP1 KMT2C SATB1 TLE1 ARID2 ZFHX3 QSER1	1.63e-05	190	118	8	int:HNF1B
Interaction	CRX interactions	SP1 SP3 ZNF536 ZNF148 KMT2C TLE1 ARID2 ZFHX3 QSER1	1.89e-05	254	118	9	int:CRX
Interaction	KLF5 interactions	HIVEP1 OGT ZNF148 FLG2 KMT2C TLE1 ARID2 QSER1	1.96e-05	195	118	8	int:KLF5
Interaction	FOXL1 interactions	ZNF536 HIVEP1 NUP98 KMT2C SATB1 TLE1 ZFHX3 COG5	2.04e-05	196	118	8	int:FOXL1
Interaction	FEV interactions	HIVEP1 ZNF148 KMT2C SATB1 TLE1 ARID2 ZFHX3 QSER1	2.62e-05	203	118	8	int:FEV
Interaction	NFIX interactions	ZNF536 HIVEP1 ZNF148 KMT2C TLE1 ARID2 ZFHX3 QSER1	5.79e-05	227	118	8	int:NFIX
Interaction	KLF3 interactions	ZNF536 HIVEP1 ZNF148 GRN TLE1 ARID2 ZFHX3 QSER1	5.97e-05	228	118	8	int:KLF3
Interaction	YWHAH interactions	TANC2 FOXO3 HIVEP1 OGT UBAP2 KLHDC2 MPDZ SOCS6 ARFGAP2 DENND1B STARD9 KRT77 TRAPPC10 PLEKHA7 PLK4 WNK3 WWC1 MAP3K2	7.24e-05	1102	118	18	int:YWHAH
Interaction	TLX1 interactions	ZNF536 HIVEP1 KMT2C SATB1 TLE1 ZFHX3 QSER1	7.75e-05	175	118	7	int:TLX1
Interaction	FBXW10B interactions	FBXW10B FBXW10	1.02e-04	3	118	2	int:FBXW10B
Interaction	LHX2 interactions	ZNF536 HIVEP1 KMT2C SATB1 TLE1 ARID2 ZFHX3	1.02e-04	183	118	7	int:LHX2
Interaction	PAX9 interactions	ZNF536 KMT2C SATB1 TLE1 ZFHX3 QSER1	1.17e-04	130	118	6	int:PAX9
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG2 RPTN CRNN	2.99e-06	7	81	3	1350
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP1 SP3	6.99e-04	9	81	2	755
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	1.06e-03	11	81	2	559
GeneFamily	WD repeat domain containing	FBXW10B DMXL2 FBXW10 EML6 TLE1 DCAF4	1.14e-03	262	81	6	362
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP1 ZNF765 SP3 ZNF536 HIVEP1 ZNF148 ZNF776 GLI3 ZNF770 ZFHX3	1.35e-03	718	81	10	28
GeneFamily	Cadherin related	DCHS1 CDHR4	2.58e-03	17	81	2	24
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	FOXO3 SP3 DMXL2 HIVEP1 OGT ZNF148 NUP98 SOCS6 FOXJ3 TLE1 ZFHX3 TMEM131 BICRAL COG5 PBX3 MN1 WWC1	3.37e-07	856	119	17	M4500
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	OGT BPIFC DNAJC6 DENND1B BTBD7 ARID2 TNRC6A TMEM131	6.19e-07	157	119	8	M7733
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FOXO3 SP3 ZNF148 FOXJ3 SATB1 BICRAL MN1 PLK4 WWC1	9.62e-06	300	119	9	M8702
Coexpression	GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP	FOXO3 DMXL2 ABCC4 LRRC37A2 BRD3 FOXJ3 CAMTA1	3.35e-05	197	119	7	M5378
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	TANC2 NLGN1 DNAJC6 SLC8A1 NEGR1 SV2A LRFN5 TNRC6A PLXNA4 CNTNAP4 ZFHX3 CEP126 CAMTA1 PBX3 WNK3 MAP3K2	4.11e-05	1106	119	16	M39071
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	SP3 DMXL2 IRX5 RNF213 SOCS6 DENND1B MECR SATB1 MIB1	5.07e-06	233	115	9	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	FOXO3 SP1 SP3 DMXL2 IRX5 ZNF148 RNF213 KMT2C DENND1B MECR SATB1 MIB1 PLXNA4 CAMTA1	7.26e-05	770	115	14	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	FOXO3 SP1 SP3 DMXL2 IRX5 ZNF148 RNF213 KMT2C DENND1B MECR SATB1 MIB1 TNRC6A CAMTA1	8.10e-05	778	115	14	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	COL6A3 SP3 HIVEP1 OGT MPDZ RNF213 SOCS6 DENND1B SATB1 SV2A PLXNA4 PBX3 WNK3 CDHR4	8.67e-05	783	115	14	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	COL6A3 HIVEP1 ADGRV1 SOCS6 ZFAND4 SATB1 NEGR1 GLI3 CNTNAP4 ZFHX3 BICRAL MN1 WNK3 CDHR4	9.65e-05	791	115	14	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500	SP3 SYNPO2 IRX5 ZNF148 SATB1 NEGR1 MIB1 CNTNAP4 ZFHX3 MEGF10	1.15e-04	429	115	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	TANC2 COL6A3 SYNPO2 IRX5 ZNF148 RNF213 TRMT2B ZFAND4 TSC22D1 SLC8A1 STARD9 GLI3 DCHS1	1.55e-04	726	115	13	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP5MC3 NLGN1 ADGRV1 PKHD1L1 PLXNA4 PLD5 DNAH9	3.66e-07	169	119	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 ABCC4 IRX5 NLGN1 ADGRV1 PLEKHA7 WWC1	6.99e-07	186	119	7	e83718fabb057100835d3357df407f283d23fe16
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 POLQ PLK4	7.24e-07	187	119	7	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 POLQ PLK4	7.24e-07	187	119	7	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 ATP13A4 ABCC4 NLGN1 ADGRV1 PLEKHA7 WWC1	7.51e-07	188	119	7	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL6A3 NLGN1 NEGR1 LRFN5 GLI3 PLXNA4 MN1	8.06e-07	190	119	7	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 FOXO3 NUP98 KMT2C SLC8A1 COG5 PLEKHA7	8.95e-07	193	119	7	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 ATP13A4 ABCC4 MFHAS1 RNF213 PLEKHA7 WWC1	9.27e-07	194	119	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ZNF536 SYNPO2 SLC8A1 NEGR1 LRFN5 MN1	1.03e-06	197	119	7	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A5 ADGRV1 PKHD1L1 CNTNAP4 PLD5 DNAH9	4.59e-06	160	119	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A5 ADGRV1 PKHD1L1 CNTNAP4 PLD5 DNAH9	4.59e-06	160	119	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO3 FBXW10B COL6A3 NEGR1 LRFN5 PLD5	7.66e-06	175	119	6	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO3 FBXW10B COL6A3 NEGR1 LRFN5 PLD5	7.66e-06	175	119	6	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 ABCC4 NLGN1 ADGRV1 PLEKHA7 WWC1	8.72e-06	179	119	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 ZNF536 SYNPO2 CNTNAP1 NEGR1 PLXNA4	8.72e-06	179	119	6	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZC2HC1C ZFAND4 RPTN CFAP74 PLD5 PLK4	9.00e-06	180	119	6	5c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZC2HC1C ZFAND4 RPTN CFAP74 PLD5 PLK4	9.00e-06	180	119	6	c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 IRX5 NLGN1 PLD5 PLEKHA7 WWC1	9.89e-06	183	119	6	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 ADGRV1 PKHD1L1 SLC8A1 CNTNAP4 DNAH9	1.02e-05	184	119	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 IRX5 NLGN1 PLD5 PLEKHA7 WWC1	1.02e-05	184	119	6	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.02e-05	184	119	6	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 SLC8A1 NEGR1 PLD5 CDHR4	1.02e-05	184	119	6	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 ADGRV1 PKHD1L1 SLC8A1 CNTNAP4 DNAH9	1.02e-05	184	119	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 ADGRV1 PKHD1L1 SLC8A1 CNTNAP4 DNAH9	1.02e-05	184	119	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXW10 ZC2HC1C PLXNA4 PLEKHA7 DNAH9 WWC1	1.05e-05	185	119	6	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 SYNPO2 NLGN1 NEGR1 LRFN5 GLI3	1.05e-05	185	119	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	LPS_only-Epithelial_alveolar\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 IRX5 NLGN1 PLD5 PLEKHA7 WWC1	1.08e-05	186	119	6	e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DMXL2 ABCC4 ANKFY1 RNF213 ARID2 POLQ	1.08e-05	186	119	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MFHAS1 NLGN1 GLI3 PBX3 WWC1	1.12e-05	187	119	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 NLGN1 ADGRV1 PLD5 PLEKHA7 WWC1	1.12e-05	187	119	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	COL6A3 SYNPO2 NLGN1 NEGR1 LRFN5 MN1	1.15e-05	188	119	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.19e-05	189	119	6	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.19e-05	189	119	6	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 ZNF536 SYNPO2 SLC8A1 NEGR1 PLD5	1.22e-05	190	119	6	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 ZNF536 SYNPO2 SLC8A1 NEGR1 PLD5	1.22e-05	190	119	6	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	TANC2 ATP13A4 NLGN1 ADGRV1 PLEKHA7 WWC1	1.26e-05	191	119	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 ZNF536 SYNPO2 NEGR1 PLXNA4 ZFHX3	1.26e-05	191	119	6	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.26e-05	191	119	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.26e-05	191	119	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.30e-05	192	119	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 ZNF536 SYNPO2 TLE1 PLXNA4 PBX3	1.30e-05	192	119	6	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 NLGN1 NEGR1 LRFN5 GLI3 MN1	1.30e-05	192	119	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	COL6A3 NLGN1 NEGR1 LRFN5 GLI3 MN1	1.30e-05	192	119	6	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZNF148 ADGRV1 USF3 DENND1B TRAPPC10 ZNF770	1.34e-05	193	119	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 NLGN1 NEGR1 LRFN5 GLI3 MN1	1.34e-05	193	119	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.38e-05	194	119	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 PLXNA4 PLD5	1.38e-05	194	119	6	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 PLXNA4 PLD5	1.38e-05	194	119	6	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 GLI3 PLD5	1.38e-05	194	119	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 NLGN1 NEGR1 GLI3 MN1 WNK3	1.42e-05	195	119	6	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	control-immature_Neutrophil\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TANC2 UBR4 GRN VPS52 DENND1B QSER1	1.46e-05	196	119	6	e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MFHAS1 NLGN1 TSC22D1 PLEKHA7 WWC1	1.50e-05	197	119	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLC8A1 NEGR1 SV2A LRFN5 ZFHX3 PBX3	1.50e-05	197	119	6	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	TANC2 DMXL2 SYNPO2 SOCS6 TREM2 PLEKHA7	1.50e-05	197	119	6	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	TANC2 DMXL2 SYNPO2 SOCS6 TREM2 PLEKHA7	1.50e-05	197	119	6	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	SYNPO2 IRX5 SOCS6 FREM3 ZFHX3	1.51e-05	116	119	5	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TANC2 ATP13A4 ABCC4 IRX5 ADGRV1 WWC1	1.55e-05	198	119	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Monocytes-Phagocytic_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DMXL2 GRN SLC8A1 SIGLEC7 TREM2 ZFHX3	1.55e-05	198	119	6	09009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO3 COL6A3 SYNPO2 NEGR1 LRFN5 PLD5	1.55e-05	198	119	6	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 ATP13A4 LRRC37A3 ADGRV1 COG5 PLEKHA7	1.55e-05	198	119	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 MPDZ GLI3 TMEM131 MN1 MEGF10	1.59e-05	199	119	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 DENND1B TLE1 GLI3 POLQ PLK4	1.64e-05	200	119	6	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 SYNPO2 NLGN1 NEGR1 LRFN5 MN1	1.64e-05	200	119	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ZNF536 SYNPO2 NEGR1 LRFN5 CEP126	1.64e-05	200	119	6	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 DENND1B TLE1 GLI3 POLQ PLK4	1.64e-05	200	119	6	c9479452ab8c51139522383f745f02171ebbd7e2
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCC4 IRX5 NLGN1 WNK3 WWC1	2.92e-05	133	119	5	5bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTNAP1 ZC2HC1C NEGR1 DCHS1 C17orf107	6.24e-05	156	119	5	5caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTNAP1 ZC2HC1C NEGR1 DCHS1 C17orf107	6.24e-05	156	119	5	758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	CNTNAP3B OGT MPDZ DNAH9 CDHR4	6.24e-05	156	119	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CNTNAP3 SATB1 SCN5A CNTNAP4 PLD5	6.43e-05	157	119	5	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 ZNF536 COL6A5 NEGR1 LRFN5	6.43e-05	157	119	5	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 PLD5	6.83e-05	159	119	5	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 PLD5	6.83e-05	159	119	5	2607b562903228274fbd96168ba826782fab0b53
ToppCell	Influenza_Severe-gd_T\|World / Disease group and Cell class	CYP1A1 CNTNAP3B CNTNAP3 AQP8 STARD9	7.25e-05	161	119	5	b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 NEGR1 LRFN5 GLI3 MEGF10	7.46e-05	162	119	5	d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 NEGR1 LRFN5 GLI3 MEGF10	7.46e-05	162	119	5	5bbd7130d4dad9035e73a439dda568195c136f31
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 NEGR1 LRFN5 GLI3 MEGF10	7.46e-05	162	119	5	eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 NEGR1 LRFN5 GLI3 MEGF10	7.46e-05	162	119	5	e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LGALS9B CRNN CFAP74 DNAH9 CDHR4	7.91e-05	164	119	5	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intermediate_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	DMXL2 MPDZ SLC8A1 ZFHX3 MN1	8.14e-05	165	119	5	c3fa9225d2f9c9e821d4fbd2315fcc98ce1f1c55
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TANC2 OGT MFHAS1 SATB1 MIB1	8.61e-05	167	119	5	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 UBAP2 EML6 ZNF770 COG5	8.61e-05	167	119	5	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZNF536 DNAJC6 NEGR1 GLI3 MEGF10	8.86e-05	168	119	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 COL6A5 NEGR1 PLD5	8.86e-05	168	119	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	MYBBP1A HIVEP1 LRRC37A PLXNA4 CEP126	8.86e-05	168	119	5	4bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP5MC3 ZNF536 CNTNAP3 TRMT2B CNTNAP4	8.86e-05	168	119	5	2572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 COL6A5 ADGRV1 COG5 MEGF10	9.37e-05	170	119	5	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	LRRC37A2 MPDZ TLE1 PLXNA4 DNAH9	9.37e-05	170	119	5	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 SCN5A CNTNAP4 PLD5 MN1	1.02e-04	173	119	5	af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ZNF536 CNTNAP3 SCN5A PLD5	1.02e-04	173	119	5	61907116a1460bc157ba73b5edd108db7dd5de4b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 SCN5A CNTNAP4 PLD5 MN1	1.02e-04	173	119	5	0ba64e5385fe714f876002520f8b5202809bf11e
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	VPS52 USF3 STARD9 CRNN PBX3	1.07e-04	175	119	5	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	LRRC37A3 LRRC37A NEGR1 PLXNA4 PBX3	1.07e-04	175	119	5	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	DMXL2 LRRC37A3 NEGR1 PLXNA4 PBX3	1.10e-04	176	119	5	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ZNF536 CNTNAP3 SCN5A PLD5	1.10e-04	176	119	5	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 LRFN5 CNTNAP4 PBX3 MN1	1.13e-04	177	119	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SYNPO2 CNTNAP3 SLC8A1 ZFHX3	1.13e-04	177	119	5	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 NLGN1 PLD5 WNK3 WWC1	1.13e-04	177	119	5	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 IRX5 EML6 NLGN1 WWC1	1.16e-04	178	119	5	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNPO2 NEGR1 LRFN5 PLD5	1.16e-04	178	119	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP1 CNTNAP3 CNTNAP4	1.57e-08	8	116	4	DOID:0060308 (implicated_via_orthology)
Disease	body fat percentage	DMXL2 HIVEP1 BRD3 NLGN1 AAGAB NEGR1 TNRC6A ZFHX3 CAMTA1	1.37e-04	488	116	9	EFO_0007800
Disease	Frontotemporal dementia	GRN TREM2	3.18e-04	7	116	2	C0338451
Disease	Semantic Dementia	GRN TREM2	3.18e-04	7	116	2	C0338462
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B CNTNAP1 CNTNAP3 NLGN1 CNTNAP4	3.44e-04	152	116	5	DOID:0060041 (implicated_via_orthology)
Disease	unipolar depression, bipolar disorder	ATP13A4 ZNF536 DENND1B STARD9 LRFN5	3.87e-04	156	116	5	EFO_0003761, MONDO_0004985
Disease	Familial Dementia	GRN TREM2	4.22e-04	8	116	2	C0751071
Disease	Senile Paranoid Dementia	GRN TREM2	4.22e-04	8	116	2	C0338630
Disease	male homosexuality	ZNF536 SLC8A1	4.22e-04	8	116	2	EFO_0008486
Disease	Primary Progressive Nonfluent Aphasia	GRN TREM2	4.22e-04	8	116	2	C0751706
Disease	Behavioral variant of frontotemporal dementia	GRN TREM2	5.42e-04	9	116	2	C4011788
Disease	supraventricular ectopy	SCN5A TREM2	5.42e-04	9	116	2	EFO_0009277
Disease	smoking status measurement	FOXO3 NLGN1 DENND1B NEGR1 TNRC6A PLXNA4 CNTNAP4 ZFHX3 BICRAL PLD5 QSER1 CAMTA1 COG5	6.50e-04	1160	116	13	EFO_0006527
Disease	Long QT Syndrome	CYP1A1 SCN5A	8.23e-04	11	116	2	C0023976
Disease	cortical surface area measurement	TANC2 FOXO3 SP1 ZNF536 MFHAS1 ADGRV1 DENND1B GLI3 GYPB TNRC6A ZFHX3 QSER1 PLEKHA7 WWC1	8.24e-04	1345	116	14	EFO_0010736
Disease	Alzheimer disease, dementia, family history of Alzheimer’s disease	EML6 MPDZ TREM2	9.00e-04	48	116	3	EFO_0009268, MONDO_0001627, MONDO_0004975
Disease	frontotemporal dementia (implicated_via_orthology)	GRN TREM2	9.86e-04	12	116	2	DOID:9255 (implicated_via_orthology)
Disease	QRS duration	MFHAS1 UBR4 SLC8A1 SCN5A COG5 MEGF10	1.18e-03	298	116	6	EFO_0005055
Disease	alcohol consumption measurement	CYP1A1 BRD3 ADGRV1 SLC8A1 NEGR1 LRFN5 GLI3 ARID2 TNRC6A PLXNA4 ZFHX3 CAMTA1 WWC1	1.21e-03	1242	116	13	EFO_0007878
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	FOXO3 HIVEP1 NLGN1 DENND1B NEGR1 TNRC6A PLXNA4 ZFHX3 BICRAL CAMTA1	1.26e-03	801	116	10	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	comparative body size at age 10, self-reported	ZNF536 MFHAS1 LRRC37A2 NEGR1 BTBD7 TNRC6A CAMTA1	1.39e-03	420	116	7	EFO_0009819
Disease	cortical thickness	FOXO3 SP1 ZNF536 FBXW10 ADGRV1 DENND1B GLI3 TNRC6A TMEM131 QSER1 CAMTA1 PLEKHA7	1.47e-03	1113	116	12	EFO_0004840
Disease	cognitive function measurement	TANC2 FOXO3 DMXL2 ZNF536 SYNPO2 ANKFY1 HIVEP1 BRD3 NEGR1 GLI3 TNRC6A PLXNA4 CNTNAP4 TMEM131	1.51e-03	1434	116	14	EFO_0008354
Disease	response to olanzapine	HIVEP1 ADGRV1	1.56e-03	15	116	2	GO_0097333
Disease	chronic obstructive pulmonary disease	COL6A3 MFHAS1 LRRC37A2 FREM3 TLE1 GYPB QSER1 MN1 DCAF4	1.61e-03	688	116	9	EFO_0000341
Disease	ovarian carcinoma	SYNPO2 ADGRV1 TLE1 GLI3 ZFHX3 PBX3	1.72e-03	321	116	6	EFO_0001075
Disease	verbal-numerical reasoning measurement	FOXO3 DMXL2 NEGR1 TNRC6A	1.81e-03	131	116	4	EFO_0008394
Disease	Dementia	GRN TREM2	2.00e-03	17	116	2	C0497327
Disease	response to radiation, Urinary retention	COL6A3 CAMTA1	2.00e-03	17	116	2	GO_0009314, HP_0000016
Disease	facial height measurement	DENND1B LRFN5 SCN5A PLD5	2.43e-03	142	116	4	EFO_0007856
Disease	obsolete_red blood cell distribution width	CYP1A1 SP1 SP3 OGT LRRC37A2 BRD3 FREM3 ZFAND4 DENND1B GYPB COG5 DCAF4 WNK3	2.48e-03	1347	116	13	EFO_0005192
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	ZNF765 ZNF536 BRD3 WNK3	2.82e-03	148	116	4	C0279702
Disease	unipolar depression	ZNF536 MFHAS1 CNTNAP1 RNF213 NLGN1 DENND1B NEGR1 LRFN5 DCHS1 ZFHX3 QSER1 CAMTA1	2.84e-03	1206	116	12	EFO_0003761
Disease	C-reactive protein measurement	SP3 DMXL2 ZNF536 MFHAS1 BRD3 CCDC168 NLGN1 DNAJC6 TREM2 QSER1 CAMTA1 DCAF4	2.84e-03	1206	116	12	EFO_0004458
Disease	cognitive function measurement, self reported educational attainment	TANC2 FOXO3 DMXL2 NEGR1 TNRC6A CNTNAP4	2.85e-03	355	116	6	EFO_0004784, EFO_0008354
Disease	diet measurement	CYP1A1 ZNF536 MFHAS1 NLGN1 NEGR1 ARID2 TNRC6A ZNF770 ZFHX3 CAMTA1 PBX3	2.86e-03	1049	116	11	EFO_0008111
Disease	osteoporosis	SP1 UBAP2 ADGRV1	3.01e-03	73	116	3	EFO_0003882
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	HIVEP1 NLGN1 AAGAB TNRC6A ZFHX3 CAMTA1	3.22e-03	364	116	6	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	risk-taking behaviour	ZNF536 HIVEP1 MFHAS1 NLGN1 AAGAB LRFN5 TNRC6A ZFHX3 CEP126	3.25e-03	764	116	9	EFO_0008579
Disease	neuroimaging measurement	FOXO3 SP1 UBAP2 DENND1B GLI3 TNRC6A QSER1 CAMTA1 PBX3 PLEKHA7 WWC1	3.30e-03	1069	116	11	EFO_0004346
Disease	progranulin measurement	GRN LRFN5	3.36e-03	22	116	2	EFO_0004625
Disease	Sensorineural Hearing Loss (disorder)	DMXL2 IRX5	3.67e-03	23	116	2	C0018784
Disease	dyslexia	TANC2 FOXO3 TMEM131 COG5	3.89e-03	162	116	4	EFO_0005424
Disease	Moderate albuminuria	CYP1A1 CAMTA1 PLEKHA7	3.90e-03	80	116	3	HP_0012594

Protein segments in the cluster

Peptide	Gene	Start	Entry
GHRQSFGTNSDVLAQ	DCAF4	316	Q8WV16
AGAQSAGTQQVAAVS	BRD3	161	Q15059
NGNSSSGFSVEQLVQ	CAMTA1	231	Q9Y6Y1
QLNSQLFIGGTATRQ	CNTNAP3	911	Q9BZ76
QRGHNSTFFGNVNES	CNTNAP1	116	P78357
RNGFQEVHSFASGQA	ATP13A4	506	Q4VNC1
SCFQRSGNNSVGAIQ	GRN	111	P28799
AHGFIQNQITFLQGS	FBXW10	321	Q5XX13
TVTFQHGQNLSFINI	ADGRV1	4456	Q8WXG9
VASNQAAGFGVQGQT	ARID2	1101	Q68CP9
ATIFQGTSGNQVTIT	ARID2	1161	Q68CP9
QLNSQLFVGGTATRQ	CNTNAP4	911	Q9C0A0
QVGGNANATAFFRQH	ARFGAP2	81	Q8N6H7
SGAAFVTVQEQGQVA	AQP8	141	O94778
SNQQGRIAASYGNAV	DMXL2	66	Q8TDJ6
LQISVSFGQRQSCQG	CDHR4	206	A6H8M9
GSTVFNGAQNGVSQL	ATP5MC3	41	P48201
SGTQSIQAQLTGSQH	QSER1	196	Q2KHR3
SLVNLNNNFGEVVGS	CYP1A1	216	P04798
GSHFNGLNQTVLNRA	IRX5	436	P78411
VSNVYSQTNGAQIQG	LRFN5	566	Q96NI6
AHGFIQNQITFLQGS	FBXW10B	321	O95170
NGAFVNAATLGAQET	ANKFY1	311	Q9P2R3
VSVVQGVFSNNGRLS	MEGF10	1081	Q96KG7
SHGGFSSNQVINVGL	OVOS1	1016	Q6IE37
SYQGSQVGANVQSQV	PBX3	361	P40426
SGTTAGTQVLQVQAQ	DCHS1	1011	Q96JQ0
GQTINTTRHSQSGQG	FLG2	1241	Q5D862
GGLFGQQNQQTTSLF	NUP98	271	P52948
NTHNGTFTILNFQGN	LRRC37A3	861	O60309
QQILSRQQSLGSAFG	GLI3	361	P10071
QQFGSQHLLVQSGSD	KMT2C	1786	Q8NEZ4
NTHNGTFTILNFQGN	LRRC37A2	861	A6NM11
NTHNGTFTILNFQGN	LRRC37A	861	A6NMS7
NGQQGIIIQNFSTRS	NEGR1	266	Q7Z3B1
NGTNLAGQSFVAEQL	MFHAS1	866	Q9Y4C4
ISGSFGINSNNQLAE	WWC1	286	Q8IX03
SVISISAANFGQNNA	KIAA2026	1416	Q5HYC2
QDGFQITVNGAVLSS	LGALS9B	26	Q3B8N2
QVTITGTNLNAGSNV	PLXNA4	971	Q9HCM2
QVARNGSFTSINSEG	MAP3K2	176	Q9Y2U5
NQGNNAAADTGHRFV	NRDE2	136	Q9H7Z3
IQPLHTFNTFTGGQN	NLGN1	831	Q8N2Q7
SQTSQAVTGGHAQIQ	CRNN	276	Q9UBG3
SQTSQAVTGGHTQIQ	CRNN	336	Q9UBG3
VSHGGAREQGQTQTQ	CRNN	366	Q9UBG3
INTASVAAFEGQVGQ	HSD17B10	151	Q99714
QQSLQQGAHSTGSSR	MYBBP1A	1116	Q9BQG0
GADVTITNNNGFNAL	MIB1	586	Q86YT6
AESGSNFSVGQRQLV	ABCC4	1171	O15439
SQHIQGNFNASGTTD	COG5	431	Q9UP83
SSQTNGETGQLVHRF	GYPB	41	P06028
NHFVQNSQGLGNVLS	BPIFC	311	Q8NFQ6
QNTAVHLVSGQTFAA	BICRAL	466	Q6AI39
SLNQFFTQTGLIHSQ	FOXJ3	511	Q9UPW0
QQFHIQSGAGSNIIS	CEP126	661	Q9P2H0
GQIQSLQQSAAVYAG	POLQ	746	O75417
QTSFQQLNGEATIGR	COL6A5	2046	A8TX70
LIDGSNNTGSVNFAV	COL6A3	246	P12111
QGSASFLRQSQQQLG	C17orf107	161	Q6ZR85
TNTQIFQLQFHTGFI	DNAJC6	316	O75061
VGGNSQAQQTFIGTS	BTBD7	16	Q9P203
LHSVNQRFGSNNTSG	KLHDC2	391	Q9Y2U9
SVIQNASNSGVGQAV	MECR	186	Q9BV79
VAFGANNLTFTGAIN	EML6	1561	Q6ZMW3
GVTNSSFQVTSQNVG	CTNS	81	O60931
EFSGVRGNALSQQVQ	DNAH9	466	Q9NYC9
GQRLQHQTGFEQTTL	CCDC168	1511	Q8NDH2
SQNQVGQHFTFVLTD	DENND1B	61	Q6P3S1
VGTQNLNGQSVFSVA	CFAP74	1411	Q9C0B2
QLNSQLFIGGTATRQ	CNTNAP3B	911	Q96NU0
AGAFVNVQQSNGETA	MPHOSPH8	656	Q99549
NRGQIQITINGFSIS	OGT	791	O15294
GFSISNGLATTQINN	OGT	801	O15294
QQQQHGVFFERFSGA	MN1	306	Q10571
TGLGNQSTRVFTQAD	FREM3	1716	P0C091
ISTQNVVGLNVGNFT	FOXO3	646	O43524
AAFNGITNSEFHTGQ	TRMT2B	386	Q96GJ1
SIFSQATNGVAEQNG	TEX55	66	Q96M34
FTQNAGTGLVINQAD	PLD5	461	Q8N7P1
GQQTVTGQANIDFLQ	FER1L5	1321	A0AVI2
NQQTTAFRHPVTGQF	PLEKHA7	76	Q6IQ23
VRNFTALNGTNGSVE	SCN5A	281	Q14524
QNLTVTVFQGEGTAS	SIGLEC7	241	Q9Y286
QSSNASVNQGVVIVG	TANC2	356	Q9HCD6
STVNNVNITAVGSFN	TSC22D1	311	Q15714
GQTRTNTFEQGTQTL	STARD9	3631	Q9P2P6
TVDGQQLQFAATGAQ	SP1	181	P08047
FNDGSQLVVQAGVSS	PLK4	911	O00444
LSELSQQGANHVNFG	SATB1	256	Q01826
QGFTGKQGTFHSQQA	SUCLG1	61	P53597
TFNFTLENQIHRGGQ	SV2A	496	Q7L0J3
NQGFSLLNSLTGTNH	AAGAB	181	Q6PD74
GANVTAFIESQNGHT	CLCA4	626	Q14CN2
NNSVQTVFQGTLAAT	RNF213	896	Q63HN8
NFRNGTSIIQGALTQ	VPS52	666	Q8N1B4
QTLVRQFQGHTDGAS	TLE1	606	Q04724
QQGFGQALVFTNSQH	UBAP2	316	Q5T6F2
QQNGFSGTSETANIQ	SYNPO2	566	Q9UMS6
VDGTNLQGFTNQQAV	MPDZ	431	O75970
GGSVQGQSSEQLNRF	SLC25A46	86	Q96AG3
GQVHSSDLQGNYIQS	SP3	361	Q02447
GNVENTLFINTSNHG	TMEM131	181	Q92545
QGTAVQGITFNVSHN	USF3	161	Q68DE3
GTNTVLQNNVVAGFG	PKHD1L1	3416	Q86WI1
FGQSSVNIDQQVVIG	TFDP3	46	Q5H9I0
TTVFQGVAGQSLQVS	TREM2	21	Q9NZC2
QVEFGNFNNLSNHSG	ZNF770	536	Q6IQ21
RNQGNFSVVGTVLAA	ZC2HC1C	181	Q53FD0
SIVSNGVNFQGSLQA	ZNF536	906	O15090
TAQGNREVFHAGTSQ	ZNF765	61	Q7L2R6
RAGIATQFSTANGQV	ZNF148	741	Q9UQR1
AGQVFNSSSGTQVLV	TRAPPC10	1231	P48553
LQNSGTGLSTNLQHF	ZFAND4	591	Q86XD8
FQGNSNNIATVDISA	PIGG	856	Q5H8A4
SHYIQSQTGEIQGQN	RPTN	581	Q6XPR3
AIQTNFQQASAVGSS	UBR4	1821	Q5T4S7
GFTGSLTNLQNQENA	HIVEP1	306	P15822
QIQRNFSGLTGTEAH	SOCS6	321	O14544
SQNKFVVGSSSNNVG	TNRC6A	291	Q8NDV7
NLQNGGGEQVFSHTA	ZFHX3	756	Q15911
SSQQLVGHYQQVSGL	WNK3	616	Q9BYP7
SKSNSFNNHQGVRTG	ZNF776	246	Q68DI1
SISVQNSQVSVNGGA	KRT77	486	Q7Z794
SIGNVTGSNAVNVFL	SLC8A1	866	P32418