Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionestrogen response element binding

AR ESR1

3.74e-0511172GO:0034056
GeneOntologyMolecularFunctionhormone binding

AR NPR3 ESR1

8.60e-05103173GO:0042562
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

AR ESR1

2.36e-0427172GO:0001091
GeneOntologyMolecularFunctionADP binding

MYO18A MSH6

7.52e-0448172GO:0043531
GeneOntologyMolecularFunctiontranscription coactivator binding

AR ESR1

9.51e-0454172GO:0001223
GeneOntologyMolecularFunctionnuclear receptor activity

AR ESR1

1.17e-0360172GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

AR ESR1

1.21e-0361172GO:0098531
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

AR ESR1

1.33e-0364172GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

AR ESR1

1.42e-0366172GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

AR ESR1

1.42e-0366172GO:0001098
GeneOntologyMolecularFunctionATPase binding

AR ESR1

3.74e-03108172GO:0051117
GeneOntologyMolecularFunctionbeta-catenin binding

AR ESR1

4.59e-03120172GO:0008013
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

RB1 AR ESR1

4.95e-03417173GO:0061629
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MYO18A MSH6

5.13e-03127172GO:0008094
GeneOntologyMolecularFunctionprotein domain specific binding

RB1 RAPGEF3 ZNF106 AR

5.52e-03875174GO:0019904
GeneOntologyMolecularFunctionsteroid binding

AR ESR1

5.61e-03133172GO:0005496
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1P1 AR NPR3 ESR1

5.72e-03884174GO:0004930
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

RB1 AR ESR1 ZNF117 ZNF317

6.09e-031459175GO:0000977
GeneOntologyMolecularFunctiontranscription coregulator binding

AR ESR1

6.20e-03140172GO:0001221
GeneOntologyMolecularFunctionnuclear receptor binding

AR ESR1

1.08e-02187172GO:0016922
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

RB1 AR ESR1

1.24e-02582173GO:0140297
GeneOntologyBiologicalProcessmammary gland branching involved in pregnancy

AR ESR1

1.34e-057172GO:0060745
GeneOntologyBiologicalProcesspositive regulation of nitric-oxide synthase activity

NPR3 ESR1

7.62e-0516172GO:0051000
GeneOntologyBiologicalProcessprostate gland growth

AR ESR1

7.62e-0516172GO:0060736
GeneOntologyBiologicalProcessmammary gland alveolus development

AR ESR1

1.46e-0422172GO:0060749
GeneOntologyBiologicalProcessmammary gland lobule development

AR ESR1

1.46e-0422172GO:0061377
GeneOntologyBiologicalProcessprotein localization to chromosome

RB1 IFFO1 ESR1

1.94e-04140173GO:0034502
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

MYO18A RB1 CLN8 RAPGEF3 AR ESR1

1.99e-041133176GO:0043066
GeneOntologyBiologicalProcesspositive regulation of monooxygenase activity

NPR3 ESR1

2.22e-0427172GO:0032770
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

MYO18A RB1 CLN8 RAPGEF3 AR ESR1

2.38e-041171176GO:0043069
GeneOntologyBiologicalProcessregulation of nitric-oxide synthase activity

NPR3 ESR1

2.56e-0429172GO:0050999
GeneOntologyBiologicalProcessbranching involved in mammary gland duct morphogenesis

AR ESR1

2.74e-0430172GO:0060444
GeneOntologyBiologicalProcessprostate gland epithelium morphogenesis

AR ESR1

3.33e-0433172GO:0060740
GeneOntologyBiologicalProcessmale gonad development

AR ESR1 ADAM5

3.50e-04171173GO:0008584
GeneOntologyBiologicalProcessprostate gland morphogenesis

AR ESR1

3.53e-0434172GO:0060512
GeneOntologyBiologicalProcessdevelopment of primary male sexual characteristics

AR ESR1 ADAM5

3.56e-04172173GO:0046546
GeneOntologyBiologicalProcesscellular response to estrogen stimulus

AR ESR1

4.19e-0437172GO:0071391
GeneOntologyBiologicalProcessmale sex differentiation

AR ESR1 ADAM5

5.44e-04199173GO:0046661
GeneOntologyBiologicalProcessregulation of monooxygenase activity

NPR3 ESR1

5.93e-0444172GO:0032768
GeneOntologyBiologicalProcessmammary gland duct morphogenesis

AR ESR1

6.20e-0445172GO:0060603
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

NPR3 ESR1

6.48e-0446172GO:0051353
GeneOntologyBiologicalProcesspositive regulation of molecular function

RB1 RAPGEF3 MSH6 AR NPR3 ESR1

6.99e-041430176GO:0044093
GeneOntologyBiologicalProcessnegative regulation of cold-induced thermogenesis

RB1 NPR3

7.05e-0448172GO:0120163
GeneOntologyBiologicalProcessgenitalia development

AR ESR1

8.92e-0454172GO:0048806
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

AR ESR1

9.94e-0457172GO:0030520
GeneOntologyBiologicalProcessprostate gland development

AR ESR1

1.17e-0362172GO:0030850
GeneOntologyBiologicalProcessmammary gland morphogenesis

AR ESR1

1.29e-0365172GO:0060443
GeneOntologyBiologicalProcessregulation of morphogenesis of a branching structure

AR ESR1

1.29e-0365172GO:0060688
GeneOntologyBiologicalProcessepithelial cell development

RAPGEF3 AR ESR1

1.30e-03269173GO:0002064
GeneOntologyBiologicalProcessmaternal process involved in female pregnancy

AR ESR1

1.62e-0373172GO:0060135
GeneOntologyBiologicalProcessgonad development

AR ESR1 ADAM5

1.65e-03292173GO:0008406
GeneOntologyBiologicalProcessdevelopment of primary sexual characteristics

AR ESR1 ADAM5

1.73e-03297173GO:0045137
GeneOntologyBiologicalProcessregulation of morphogenesis of an epithelium

AR ESR1

1.76e-0376172GO:1905330
GeneOntologyBiologicalProcessurogenital system development

AR ESR1

1.90e-0379172GO:0001655
GeneOntologyBiologicalProcessregulation of miRNA transcription

AR ESR1

2.09e-0383172GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

AR ESR1

2.14e-0384172GO:0061614
GeneOntologyBiologicalProcessmammary gland epithelium development

AR ESR1

2.14e-0384172GO:0061180
GeneOntologyBiologicalProcessregulation of oxidoreductase activity

NPR3 ESR1

2.14e-0384172GO:0051341
GeneOntologyBiologicalProcessnegative regulation of muscle cell apoptotic process

RAPGEF3 ESR1

2.30e-0387172GO:0010656
GeneOntologyBiologicalProcessnegative regulation of smooth muscle cell proliferation

NPR3 ESR1

2.45e-0390172GO:0048662
GeneOntologyBiologicalProcesscellular response to hormone stimulus

RB1 ZNF106 AR ESR1

2.52e-03727174GO:0032870
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

RB1 MSH6 AR ESR1 ADAM5

2.58e-031235175GO:0003006
GeneOntologyBiologicalProcesssex differentiation

AR ESR1 ADAM5

2.81e-03352173GO:0007548
GeneOntologyBiologicalProcessresponse to estrogen

AR ESR1

3.20e-03103172GO:0043627
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

AR ESR1

3.20e-03103172GO:2000628
HumanPhenoIncreased serum estradiol

AR ESR1

4.15e-05962HP:0025134
HumanPhenoElevated alkaline phosphatase of bone origin

NPR3 ESR1

8.97e-051362HP:0010639
HumanPhenoElevated tissue non-specific alkaline phosphatase

NPR3 ESR1

1.56e-041762HP:0010679
HumanPhenoElevated circulating alkaline phosphatase concentration

RB1 NPR3 ESR1

2.30e-0411863HP:0003155
HumanPhenoAbnormality of alkaline phosphatase level

RB1 NPR3 ESR1

3.14e-0413163HP:0004379
MousePhenomotor neuron degeneration

CLN8 ZNF106 AR

3.01e-0638113MP:0000938
MousePhenoincreased body size

RB1 RAPGEF3 AR NPR3 ESR1

8.36e-06409115MP:0001264
MousePhenoskeletal muscle atrophy

RB1 ZNF106 AR

8.80e-0654113MP:0009417
MousePhenopreneoplasia

RB1 AR

2.02e-059112MP:0002009
MousePhenodecreased skeletal muscle size

RB1 ZNF106 AR

2.99e-0581113MP:0010240
MousePhenoabnormal skeletal muscle size

RB1 ZNF106 AR

4.53e-0593113MP:0009458
MousePhenoabnormal epididymal fat pad weight

RAPGEF3 NPR3 ESR1

4.67e-0594113MP:0020998
MousePhenomuscular atrophy

RB1 ZNF106 AR

4.98e-0596113MP:0002269
MousePhenoabnormal white fat cell size

RAPGEF3 NPR3 ESR1

5.62e-05100113MP:0009132
MousePhenopremature death

RB1 CLN8 MSH6 ZNF106 AR NPR3

5.92e-051051116MP:0002083
MousePhenoabnormal white adipose tissue morphology

RB1 RAPGEF3 NPR3 ESR1

7.93e-05321114MP:0002970
MousePhenoabnormal epididymal fat pad morphology

RAPGEF3 NPR3 ESR1

1.12e-04126113MP:0006319
MousePhenoabnormal white fat cell morphology

RAPGEF3 NPR3 ESR1

1.15e-04127113MP:0009117
MousePhenodecreased tumor-free survival time

RB1 MSH6

1.17e-0421112MP:0014237
MousePhenoabnormal tumor-free survival time

RB1 MSH6

1.17e-0421112MP:0014235
MousePhenodecreased skeletal muscle mass

RB1 ZNF106 AR

1.26e-04131113MP:0004819
MousePhenoincreased total tissue mass

RB1 RAPGEF3 AR ESR1

1.29e-04364114MP:0012323
MousePhenoincreased body weight

RB1 RAPGEF3 AR ESR1

1.29e-04364114MP:0001260
MousePhenosmall dorsal root ganglion

RB1 ZNF106

1.54e-0424112MP:0000964
MousePhenoincreased circulating testosterone level

AR ESR1

1.81e-0426112MP:0002781
MousePhenoabnormal skeletal muscle mass

RB1 ZNF106 AR

1.84e-04149113MP:0004817
MousePhenoabnormal motor neuron morphology

CLN8 ZNF106 AR

1.91e-04151113MP:0000937
MousePhenoskeletal muscle fiber atrophy

ZNF106 AR

2.26e-0429112MP:0009413
MousePhenoabnormal muscle electrophysiology

ZNF106 AR

2.76e-0432112MP:0004145
MousePhenoabnormal macrophage morphology

RB1 ZNF106 NPR3 ESR1

3.26e-04463114MP:0002446
MousePhenoabnormal spinal cord grey matter morphology

CLN8 ZNF106 AR

3.26e-04181113MP:0008503
MousePhenoincreased circulating luteinizing hormone level

AR ESR1

3.30e-0435112MP:0001751
MousePhenoneurodegeneration

RB1 CLN8 ZNF106 AR

3.39e-04468114MP:0002229
MousePhenoincreased luteinizing hormone level

AR ESR1

3.90e-0438112MP:0005133
MousePhenoabnormal mammary gland morphology

RB1 AR ESR1

4.44e-04201113MP:0000627
MousePhenoabnormal apocrine gland morphology

RB1 AR ESR1

4.44e-04201113MP:0013554
MousePhenoabnormal skeletal muscle morphology

RB1 ZNF106 AR ESR1

4.64e-04508114MP:0000759
MousePhenoabnormal retroperitoneal fat pad morphology

NPR3 ESR1

4.99e-0443112MP:0005337
MousePhenoincreased variability of skeletal muscle fiber size

ZNF106 AR

4.99e-0443112MP:0009403
MousePhenoincreased circulating follicle stimulating hormone level

AR ESR1

5.23e-0444112MP:0001750
MousePhenoincreased follicle stimulating hormone level

AR ESR1

5.97e-0447112MP:0005131
MousePhenokyphosis

RB1 ZNF106 NPR3

6.50e-04229113MP:0000160
MousePhenoabnormal vagina morphology

AR ESR1

7.03e-0451112MP:0001139
MousePhenoabnormal external male genitalia morphology

ZNF106 AR

7.59e-0453112MP:0009199
MousePhenoabnormal fat cell morphology

RAPGEF3 NPR3 ESR1

7.63e-04242113MP:0009115
MousePhenoincreased reproductive system tumor incidence

MSH6 AR

8.78e-0457112MP:0010287
MousePhenotesticular atrophy

AR ESR1

9.40e-0459112MP:0003205
MousePhenoabnormal muscle morphology

MYO18A RB1 ZNF106 AR ESR1

9.47e-041106115MP:0002108
MousePhenoabnormal abdominal fat pad morphology

RAPGEF3 NPR3 ESR1

9.61e-04262113MP:0000010
MousePhenodecreased circulating gonadotropin level

AR ESR1

9.72e-0460112MP:0003363
MousePhenodecreased circulating testosterone level

AR ESR1

9.72e-0460112MP:0002780
MousePhenoincreased circulating mineral level

CLN8 ZNF106 AR NPR3

1.02e-03626114MP:0014547
MousePhenoabnormal mammary gland duct morphology

RB1 ESR1

1.04e-0362112MP:0009503
MousePhenoincreased circulating gonadotropin level

AR ESR1

1.11e-0364112MP:0003362
MousePhenoabnormal luteinizing hormone level

AR ESR1

1.11e-0364112MP:0003969
MousePhenodecreased epididymal fat pad weight

RAPGEF3 NPR3

1.14e-0365112MP:0009289
MousePhenoabnormal spinal cord morphology

CLN8 ZNF106 AR

1.14e-03278113MP:0000955
MousePhenodecreased white fat cell size

RAPGEF3 NPR3

1.21e-0367112MP:0009133
MousePhenoabnormal inguinal fat pad morphology

NPR3 ESR1

1.28e-0369112MP:0005336
MousePhenoincreased mineral level

CLN8 ZNF106 AR NPR3

1.30e-03668114MP:0014535
MousePhenoabnormal mesonephros morphology

AR ESR1

1.40e-0372112MP:0008487
MousePhenoabnormal mammary gland epithelium morphology

RB1 ESR1

1.47e-0374112MP:0009504
MousePhenoabnormal somatic sensory system morphology

RB1 CLN8 ZNF106 AR

1.57e-03702114MP:0000959
MousePhenoabnormal mononuclear phagocyte morphology

RB1 ZNF106 NPR3 ESR1

1.59e-03705114MP:0008248
MousePhenoabnormal osteoblast cell number

NPR3 ESR1

1.59e-0377112MP:0004987
MousePhenoabnormal fat pad morphology

RAPGEF3 NPR3 ESR1

1.62e-03314113MP:0005334
MousePhenoabnormal spine curvature

RB1 ZNF106 NPR3

1.68e-03318113MP:0004174
MousePhenocentrally nucleated skeletal muscle fibers

ZNF106 AR

1.72e-0380112MP:0009404
MousePhenoabnormal professional antigen presenting cell morphology

RB1 ZNF106 NPR3 ESR1

1.78e-03726114MP:0008195
MousePhenoabnormal circulating testosterone level

AR ESR1

1.89e-0384112MP:0005180
MousePhenoabnormal circulating androgen level

AR ESR1

1.89e-0384112MP:0009819
MousePhenoabnormal myeloid leukocyte morphology

RB1 ZNF106 AR NPR3 ESR1

1.92e-031292115MP:0008250
MousePhenoabnormal reflex

IFFO2 RB1 CLN8 ZNF106 ESR1

1.94e-031294115MP:0001961
MousePhenoabnormal cartilage morphology

RB1 NPR3 ESR1

1.97e-03336113MP:0000163
MousePhenodecreased circulating pituitary hormone level

AR ESR1

2.12e-0389112MP:0005118
MousePhenoabnormal follicle stimulating hormone level

AR ESR1

2.12e-0389112MP:0003967
MousePhenoaxon degeneration

CLN8 ZNF106

2.22e-0391112MP:0005405
MousePhenohunched posture

RB1 NPR3

2.22e-0391112MP:0001505
MousePhenoabnormal testosterone level

AR ESR1

2.27e-0392112MP:0011385
MousePhenoabnormal vertebral column morphology

RB1 ZNF106 NPR3 ESR1

2.39e-03787114MP:0004703
MousePhenoabnormal adipose tissue morphology

RB1 RAPGEF3 AR NPR3 ESR1

2.43e-031361115MP:0000003
MousePhenodecreased skeletal muscle fiber size

ZNF106 AR

2.52e-0397112MP:0009400
MousePhenodecreased fat cell size

RAPGEF3 NPR3

2.52e-0397112MP:0009269
MousePhenoadipose tissue phenotype

RB1 RAPGEF3 AR NPR3 ESR1

2.61e-031383115MP:0005375
Domainzf-C4

AR ESR1

6.11e-0446152PF00105
DomainNUCLEAR_REC_DBD_1

AR ESR1

6.11e-0446152PS00031
DomainZnf_hrmn_rcpt

AR ESR1

6.11e-0446152IPR001628
DomainZnF_C4

AR ESR1

6.11e-0446152SM00399
DomainNUCLEAR_REC_DBD_2

AR ESR1

6.11e-0446152PS51030
Domain-

AR ESR1

6.37e-04471521.10.565.10
DomainNucl_hrmn_rcpt_lig-bd

AR ESR1

6.65e-0448152IPR000536
DomainHormone_recep

AR ESR1

6.65e-0448152PF00104
DomainHOLI

AR ESR1

6.65e-0448152SM00430
Domain-

AR ESR1

9.37e-04571523.30.50.10
DomainZnf_NHR/GATA

AR ESR1

9.70e-0458152IPR013088
DomainFilament

IFFO2 IFFO1

1.45e-0371152SM01391
DomainIF

IFFO2 IFFO1

1.66e-0376152IPR001664
Domainzf-C2H2

ZNF106 ZNF117 ZNF317

1.66e-02693153PF00096
DomainZINC_FINGER_C2H2_2

ZNF106 ZNF117 ZNF317

2.23e-02775153PS50157
DomainZINC_FINGER_C2H2_1

ZNF106 ZNF117 ZNF317

2.24e-02777153PS00028
DomainZnf_C2H2-like

ZNF106 ZNF117 ZNF317

2.39e-02796153IPR015880
DomainZnf_C2H2

ZNF106 ZNF117 ZNF317

2.46e-02805153IPR007087
DomainZnF_C2H2

ZNF106 ZNF117 ZNF317

2.49e-02808153SM00355
Domainzf-C2H2_6

ZNF117 ZNF317

2.56e-02314152PF13912
PathwayWP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER

RB1 MSH6 AR

5.33e-05110103M48043
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2

RB1 AR ESR1

6.74e-05119103M27785
PathwayREACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION

RB1 AR

1.24e-0424102M27803
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

AR ESR1

1.70e-0428102MM15042
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

AR ESR1

1.95e-0430102M27323
PathwayREACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT

RB1 AR

2.08e-0431102M27805
PathwayWP_CANCER_PATHWAYS

RB1 MSH6 AR ESR1

2.92e-04507104M48302
PathwayWP_NUCLEAR_RECEPTORS

AR ESR1

3.14e-0438102MM15865
PathwayWP_NUCLEAR_RECEPTORS

AR ESR1

3.14e-0438102M39657
PathwayPID_FOXM1_PATHWAY

RB1 ESR1

3.48e-0440102M176
PathwayPID_HNF3A_PATHWAY

AR ESR1

4.22e-0444102M285
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2586

RB1 ESR1

4.61e-0446102M39661
PathwayPID_HES_HEY_PATHWAY

RB1 AR

5.02e-0448102M288
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

AR ESR1

5.02e-0448102MM14987
PathwayWP_INTEGRATED_CANCER_PATHWAY

RB1 MSH6

5.02e-0448102M39628
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

AR ESR1

6.12e-0453102M8276
PathwayPID_ATF2_PATHWAY

RB1 ESR1

7.58e-0459102M166
PathwayKEGG_PATHWAYS_IN_CANCER

RB1 MSH6 AR

1.29e-03325103M12868
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

AR ESR1

1.46e-0382102M2
PathwayWP_GLIOBLASTOMA_SIGNALING

RB1 MSH6

1.49e-0383102M39637
PathwayKEGG_PROSTATE_CANCER

RB1 AR

1.72e-0389102M13191
PathwayWP_RETINOBLASTOMA_GENE_IN_CANCER

RB1 MSH6

1.75e-0390102M39678
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

RB1 AR

1.79e-0391102M39700
PathwayWP_IL6_SIGNALING_PATHWAY

RB1 AR

2.16e-03100102MM15826
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

MYO18A RB1 ESR1

3.58e-03464103M27547
PathwayWP_MALE_INFERTILITY

AR ESR1

4.48e-03145102M39856
PathwayWP_BREAST_CANCER_PATHWAY

RB1 ESR1

5.04e-03154102M39739
PathwayREACTOME_SUMOYLATION

AR ESR1

6.04e-03169102MM14919
PathwayREACTOME_SUMOYLATION

AR ESR1

7.50e-03189102M27214
Pubmed

Androgen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female mice.

AR ESR1

2.25e-07217225076121
Pubmed

The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer.

AR ESR1

2.25e-07217233462444
Pubmed

Research resource: interplay between the genomic and transcriptional networks of androgen receptor and estrogen receptor α in luminal breast cancer cells.

AR ESR1

2.25e-07217223023562
Pubmed

Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer.

AR ESR1

2.25e-07217218559568
Pubmed

Estren behaves as a weak estrogen rather than a nongenomic selective activator in the mouse uterus.

AR ESR1

2.25e-07217216469803
Pubmed

Expression of estrogen and androgen receptors in children with hypospadias: preliminary report.

AR ESR1

2.25e-07217217453687
Pubmed

BA321, a novel carborane analog that binds to androgen and estrogen receptors, acts as a new selective androgen receptor modulator of bone in male mice.

AR ESR1

2.25e-07217227402268
Pubmed

Selected estrogen receptor 1 and androgen receptor gene polymorphisms in relation to risk of breast cancer and fibrocystic breast conditions among Chinese women.

AR ESR1

2.25e-07217220846920
Pubmed

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression.

RB1 AR

2.25e-07217221099110
Pubmed

Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells.

RB1 AR

2.25e-0721729675141
Pubmed

Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer.

RB1 AR

2.25e-07217227148695
Pubmed

Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney.

AR ESR1

2.25e-07217237673062
Pubmed

A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals.

AR ESR1

2.25e-07217232392092
Pubmed

Association of oestrogen receptor alpha polymorphisms and androgen receptor CAG trinucleotide repeats with male infertility: a study in 109 Greek infertile men.

AR ESR1

2.25e-07217212031042
Pubmed

ESR1, AR, body size, and breast cancer risk in Hispanic and non-Hispanic white women living in the Southwestern United States.

AR ESR1

2.25e-07217217187234
Pubmed

Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer.

AR ESR1

2.25e-07217235618789
Pubmed

Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor-Positive Breast Cancer Models with a Distinct Mechanism of Action.

AR ESR1

2.25e-07217228974548
Pubmed

Cellular localization of androgen and estrogen receptors in mouse-derived motoneuron hybrid cells and mouse facial motoneurons.

AR ESR1

2.25e-07217217638386
Pubmed

The Role of the Androgen Receptor Signaling in Breast Malignancies.

AR ESR1

2.25e-07217229187427
Pubmed

Roles of estrogen receptor alpha and androgen receptor in the regulation of neuronal nitric oxide synthase.

AR ESR1

2.25e-07217212389206
Pubmed

Caloric restriction increases ratio of estrogen to androgen receptors expression in murine ovaries--potential therapeutic implications.

AR ESR1

2.25e-07217226264910
Pubmed

The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis.

AR ESR1

2.25e-0721729647203
Pubmed

Concurrent Androgen and Estrogen Ablation and Inhibition of Steroid Biosynthetic Enzyme Treatment for Castration-resistant Prostate Cancer.

AR ESR1

2.25e-07217227466486
Pubmed

Androgen signaling negatively controls group 2 innate lymphoid cells.

AR ESR1

2.25e-07217228484078
Pubmed

Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses' Health Studies.

AR ESR1

2.25e-07217230445651
Pubmed

Inactivation of AR or ERα in Extrahypothalamic Neurons Does not Affect Osteogenic Response to Loading in Male Mice.

AR ESR1

2.25e-07217235640239
Pubmed

The association of androgen- and oestrogen-receptor gene polymorphisms with urolithiasis in men.

AR ESR1

2.25e-07217211564035
Pubmed

AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors.

AR ESR1

2.25e-07217232344660
Pubmed

Combined Androgen and Estrogen Receptor Status in Breast Cancer: Treatment Prediction and Prognosis in a Population-Based Prospective Cohort.

AR ESR1

2.25e-07217225904752
Pubmed

Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha.

AR ESR1

2.25e-07217218809737
Pubmed

Hypothalamic expression of oestrogen receptor α and androgen receptor is sex-, age- and region-dependent in mice.

AR ESR1

2.25e-07217225599767
Pubmed

Association of receptor expression with prostate volume in benign prostatic hyperplasia.

AR ESR1

2.25e-07217230706868
Pubmed

Hormonal modulation of ESR1 mutant metastasis.

AR ESR1

2.25e-07217233323970
Pubmed

Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.

AR ESR1

2.25e-07217222508765
Pubmed

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein.

RB1 AR

2.25e-07217227760327
Pubmed

Sex hormones regulate metainflammation in diet-induced obesity in mice.

AR ESR1

2.25e-07217234599964
Pubmed

Interaction between estrogens and androgen receptor genes microsatellites, prostate-specific antigen and androgen receptor expressions in breast cancer.

AR ESR1

2.25e-07217220353269
Pubmed

Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators.

AR ESR1

2.25e-07217223996526
Pubmed

Aggression and arginine vasopressin immunoreactivity regulation by androgen receptor and estrogen receptor alpha.

AR ESR1

2.25e-07217214960012
Pubmed

AR collaborates with ERα in aromatase inhibitor-resistant breast cancer.

AR ESR1

2.25e-07217225178514
Pubmed

The relation of the XbaI and PvuII polymorphisms of the estrogen receptor gene and the CAG repeat polymorphism of the androgen receptor gene to peak bone mass and bone turnover rate among young healthy men.

AR ESR1

2.25e-07217215827868
Pubmed

Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice.

AR ESR1

2.25e-07217219821763
Pubmed

Differential regulation of androgen and glucocorticoid receptors by retinoblastoma protein.

RB1 AR

2.25e-0721729813067
Pubmed

Expression of sexual hormones receptors in oral squamous cell carcinoma.

AR ESR1

2.25e-07217221781458
Pubmed

Genomics of sex hormone receptor signaling in hepatic sexual dimorphism.

AR ESR1

2.25e-07217228554805
Pubmed

New insights into the expression of androgen and estrogen receptors of the appendix testis in congenital cryptorchidism.

AR ESR1

2.25e-07217232109207
Pubmed

Expression of androgen and estrogen receptors in sertoli cells: studies using the mouse SK11 cell line.

AR ESR1

6.74e-07317216166216
Pubmed

Estrogen receptors alpha and beta (ERalpha and ERbeta) and androgen receptor (AR) in human sperm: localization of ERbeta and AR in mitochondria of the midpiece.

AR ESR1

6.74e-07317216123086
Pubmed

Localization of steroid hormone receptors in the apocrine sweat glands of the human axilla.

AR ESR1

6.74e-07317215609040
Pubmed

Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors.

AR ESR1

6.74e-07317224680642
Pubmed

Association between estrogen and androgen receptor genes and prostate cancer risk.

AR ESR1

6.74e-07317218952763
Pubmed

Expression Patterns of ERα, ERβ, AR, SIRT1, SIRT2, and SIRT3 in Prostate Cancer Tissue and Normal Prostate Tissue.

AR ESR1

6.74e-07317233788729
Pubmed

Investigation of hormone receptor genes in migraine.

AR ESR1

6.74e-07317215654614
Pubmed

Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different pathways.

AR ESR1

6.74e-07317220435684
Pubmed

Microsatellite profile in hormonal receptor genes associated with breast cancer.

AR ESR1

6.74e-07317216317584
Pubmed

The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts.

AR ESR1

6.74e-07317225704845
Pubmed

Comparative analysis of Rb1, P16 and ER as diagnostic, prognostic and potential targets for therapeutic agents in ovarian epithelial tumors: an immunohistochemical study of 130 ovarian carcinomas.

RB1 ESR1

6.74e-07317226043844
Pubmed

Increase and Redistribution of Sex Hormone Receptors in Premenopausal Women Are Associated with Varicose Vein Remodelling.

AR ESR1

6.74e-07317230250632
Pubmed

17beta-estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta.

AR ESR1

6.74e-07317216223864
Pubmed

Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism.

AR ESR1

6.74e-07317219592451
Pubmed

Steroid hormones polymorphisms and cholelithiasis in Greek population.

AR ESR1

6.74e-07317217241382
Pubmed

Loss of heterozygosity in tumor tissue in hormonal receptor genes is associated with poor prognostic criteria in breast cancer.

AR ESR1

6.74e-07317225979597
Pubmed

Expression of androgen receptor, estrogen receptor alpha and beta in the dermal papilla of human hair follicles in vivo.

AR ESR1

6.74e-07317215541640
Pubmed

Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells.

AR ESR1

6.74e-07317230513371
Pubmed

Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer.

AR ESR1

6.74e-07317216365013
Pubmed

[The relationship between the expression of amplified in breast cancer 1、androgen receptor and tamoxifen resistance in breast cancer].

AR ESR1

6.74e-07317237246005
Pubmed

Transgenic introduction of androgen receptor into estrogen-receptor-, progesterone-receptor-, and androgen-receptor-negative breast cancer cells renders them responsive to hormonal manipulation.

AR ESR1

6.74e-07317216647340
Pubmed

Microsatellite variation of ESR1, ESR2, and AR in Serbian women with primary ovarian insufficiency.

AR ESR1

6.74e-07317230156935
Pubmed

The influence of microsatellite polymorphisms in sex steroid receptor genes ESR1, ESR2 and AR on sex differences in brain structure.

AR ESR1

6.74e-07317232593802
Pubmed

Estrogens and development of the mouse and human external genitalia.

AR ESR1

6.74e-07317233092894
Pubmed

Expression of androgen and estrogen receptors in human scalp mesenchymal cells in vitro.

AR ESR1

6.74e-07317217160687
Pubmed

Polymorphisms of the androgen receptor gene and the estrogen receptor beta gene are associated with androgen levels in women.

AR ESR1

6.74e-07317211397855
Pubmed

Expression patterns of sex steroid receptors in developing mesonephros of the male mouse: three-dimensional analysis.

AR ESR1

6.74e-07317237335379
Pubmed

A functional androgen receptor is not sufficient to allow estradiol to protect bone after gonadectomy in estradiol receptor-deficient mice.

AR ESR1

6.74e-07317212727923
Pubmed

Allelic variants of aromatase and the androgen and estrogen receptors: toward a multigenic model of prostate cancer risk.

AR ESR1

6.74e-07317211595700
Pubmed

Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation.

RB1 AR

6.74e-07317214645241
Pubmed

A Novel Functional Domain of Tab2 Involved in the Interaction with Estrogen Receptor Alpha in Breast Cancer Cells.

AR ESR1

6.74e-07317227992601
Pubmed

Targeting androgen receptor in estrogen receptor-negative breast cancer.

AR ESR1

6.74e-07317221741601
Pubmed

Expression of estrogen and androgen receptors in differentiated thyroid cancer: an additional criterion to assess the patient's risk.

AR ESR1

6.74e-07317222531679
Pubmed

Neuroendocrine stress response is moderated by sex and sex hormone receptor polymorphisms.

AR ESR1

6.74e-07317230300610
Pubmed

Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex.

AR ESR1

6.74e-07317227690341
Pubmed

CpG islands aberrant hypermethylation of sex hormone receptor superfamily might be involved in the development of leukemic neoplasms.

AR ESR1

6.74e-07317220299092
Pubmed

Association of repeat polymorphisms in the estrogen receptors alpha, beta, and androgen receptor genes with knee osteoarthritis.

AR ESR1

6.74e-07317216098017
Pubmed

Brain masculinization requires androgen receptor function.

AR ESR1

6.74e-07317214747651
Pubmed

The distribution of estrogen receptor beta is distinct to that of estrogen receptor alpha and the androgen receptor in human skin and the pilosebaceous unit.

AR ESR1

6.74e-07317212895004
Pubmed

Detection of mRNA levels for the estrogen alpha, estrogen beta and androgen nuclear receptor genes in archival breast cancer tissue.

AR ESR1

6.74e-07317216046054
Pubmed

Correlating androgen and estrogen steroid receptor expression with coronary calcification and atherosclerosis in men without known coronary artery disease.

AR ESR1

6.74e-07317215536156
Pubmed

Estrogen receptor β expression and androgen receptor phosphorylation correlate with a poor clinical outcome in hormone-naive prostate cancer and are elevated in castration-resistant disease.

AR ESR1

6.74e-07317223580588
Pubmed

Comparison of the polymorphisms of androgen receptor gene and estrogen alpha and beta gene between adolescent females with first-onset major depressive disorder and controls.

AR ESR1

6.74e-07317217365134
Pubmed

Combined profile of the tandem repeats CAG, TA and CA of the androgen and estrogen receptor genes in breast cancer.

AR ESR1

6.74e-07317216791593
Pubmed

Expression, distribution and regulation of sex steroid hormone receptors in mouse heart.

AR ESR1

6.74e-07317219255502
Pubmed

Prohibitin promotes androgen receptor activation in ER-positive breast cancer.

AR ESR1

6.74e-07317228272969
Pubmed

Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells.

AR ESR1

6.74e-07317215205473
Pubmed

Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy.

AR ESR1

6.74e-07317220615892
Pubmed

Effects of sex steroids on the pattern of methylation and expression of the promoter region of estrogen and androgen receptors in people with gender dysphoria under cross-sex hormone treatment.

AR ESR1

6.74e-07317228539237
Pubmed

Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane.

AR ESR1

6.74e-07317220439495
Pubmed

Association of repeat polymorphisms in the estrogen receptors alpha, beta (ESR1, ESR2) and androgen receptor (AR) genes with the occurrence of breast cancer.

AR ESR1

6.74e-07317217904846
Pubmed

Localization of androgen and estrogen receptors in adult male mouse reproductive tract.

AR ESR1

6.74e-07317212399534
Pubmed

Influence of surgical trauma on the mRNA expression of sex hormone receptors in PBMCs in male and female patients.

AR ESR1

6.74e-07317218297304
Pubmed

Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells.

AR ESR1

6.74e-07317215772083
InteractionSKIL interactions

RB1 ZNF106 AR ESR1

1.99e-06119164int:SKIL
InteractionCCND1 interactions

RB1 MSH6 ZNF106 AR ESR1

2.14e-06286165int:CCND1
InteractionKDM4A interactions

RB1 AR ESR1

1.66e-0564163int:KDM4A
InteractionUHRF1 interactions

RB1 MSH6 AR ESR1

1.82e-05208164int:UHRF1
InteractionMED13 interactions

RB1 AR ESR1

4.04e-0586163int:MED13
InteractionPOU2F3 interactions

RB1 ESR1

6.17e-0515162int:POU2F3
InteractionLIMCH1 interactions

MYO18A AR ESR1

6.33e-05100163int:LIMCH1
InteractionFLII interactions

MYO18A MSH6 AR ESR1

7.41e-05298164int:FLII
InteractionCREBBP interactions

RB1 MSH6 ZNF106 AR ESR1

7.59e-05599165int:CREBBP
InteractionGTF2H1 interactions

RB1 AR ESR1

7.75e-05107163int:GTF2H1
InteractionLIN9 interactions

RB1 AR ESR1

8.64e-05111163int:LIN9
InteractionTFAP2A interactions

MYO18A RB1 AR

9.36e-05114163int:TFAP2A
InteractionLDB1 interactions

RB1 AR ESR1

9.60e-05115163int:LDB1
InteractionITPRID2 interactions

MYO18A AR ESR1

1.09e-04120163int:ITPRID2
InteractionRBM26 interactions

RB1 AR ESR1

1.38e-04130163int:RBM26
InteractionZBTB7A interactions

RB1 AR ESR1

1.41e-04131163int:ZBTB7A
InteractionAHR interactions

RB1 AR ESR1

1.45e-04132163int:AHR
InteractionTOLLIP interactions

MYO18A ZNF106 AR ESR1

1.50e-04358164int:TOLLIP
InteractionCDC25B interactions

MSH6 AR ESR1

1.51e-04134163int:CDC25B
InteractionGRHL2 interactions

AR ESR1

1.75e-0425162int:GRHL2
InteractionHDAC7 interactions

MYO18A AR ESR1

1.76e-04141163int:HDAC7
InteractionPOU2F2 interactions

AR ESR1

1.90e-0426162int:POU2F2
InteractionNCOA6 interactions

RB1 AR ESR1

1.91e-04145163int:NCOA6
InteractionCDC42BPA interactions

MYO18A AR ESR1

1.95e-04146163int:CDC42BPA
InteractionBRD8 interactions

RB1 AR ESR1

2.07e-04149163int:BRD8
InteractionTRIB3 interactions

MYO18A KLHL38 AR

2.55e-04160163int:TRIB3
InteractionSKI interactions

RB1 AR ESR1

2.55e-04160163int:SKI
InteractionCGREF1 interactions

MYO18A ESR1

2.71e-0431162int:CGREF1
InteractionGRB2 interactions

MYO18A RB1 ZNF106 AR ESR1

3.05e-04806165int:GRB2
InteractionRAP1A interactions

RAPGEF3 AR ESR1

3.10e-04171163int:RAP1A
InteractionMTA3 interactions

RB1 AR ESR1

3.21e-04173163int:MTA3
InteractionUBE3A interactions

KLHL38 RB1 AR ESR1

3.34e-04441164int:UBE3A
InteractionHIF1A interactions

RB1 MSH6 AR ESR1

3.34e-04441164int:HIF1A
InteractionPNRC2 interactions

AR ESR1

3.46e-0435162int:PNRC2
InteractionDDHD1 interactions

MYO18A IFFO1

3.87e-0437162int:DDHD1
InteractionCITED1 interactions

RB1 ESR1

3.87e-0437162int:CITED1
InteractionSMARCA4 interactions

MYO18A RB1 AR ESR1

3.99e-04462164int:SMARCA4
InteractionCCAR1 interactions

RB1 AR ESR1

4.03e-04187163int:CCAR1
InteractionZBTB16 interactions

RB1 AR ESR1

4.03e-04187163int:ZBTB16
InteractionPELP1 interactions

RB1 AR ESR1

4.16e-04189163int:PELP1
InteractionGAK interactions

RB1 ZNF106 AR

4.16e-04189163int:GAK
InteractionPPP1CB interactions

MYO18A RB1 ZNF106 AR

4.22e-04469164int:PPP1CB
InteractionKMT5B interactions

RB1 ESR1

4.30e-0439162int:KMT5B
InteractionPPAN interactions

RB1 ESR1 ZNF317

4.42e-04193163int:PPAN
InteractionCHD8 interactions

MSH6 AR ESR1

4.42e-04193163int:CHD8
InteractionCRACD interactions

MYO18A ESR1

4.53e-0440162int:CRACD
InteractionNR0B1 interactions

AR ESR1

4.53e-0440162int:NR0B1
InteractionPSMC3IP interactions

AR ESR1

4.76e-0441162int:PSMC3IP
InteractionPIK3R3 interactions

RB1 AR ESR1

4.76e-04198163int:PIK3R3
InteractionE2F1 interactions

RB1 AR ESR1

4.90e-04200163int:E2F1
InteractionGBP1 interactions

ESR1 ZNF317

4.99e-0442162int:GBP1
InteractionMYO5A interactions

MYO18A AR ESR1

5.19e-04204163int:MYO5A
InteractionCASZ1 interactions

AR ESR1

5.24e-0443162int:CASZ1
InteractionPRDM2 interactions

RB1 ESR1

5.24e-0443162int:PRDM2
InteractionGSN interactions

MYO18A AR ESR1

5.81e-04212163int:GSN
InteractionBCL9L interactions

AR ESR1

6.53e-0448162int:BCL9L
InteractionMORF4L1 interactions

RB1 MSH6 ESR1

6.56e-04221163int:MORF4L1
InteractionEXOSC10 interactions

ZNF106 AR ESR1

6.73e-04223163int:EXOSC10
InteractionRNF14 interactions

AR ESR1

6.80e-0449162int:RNF14
InteractionCCNT1 interactions

RB1 AR ESR1

6.91e-04225163int:CCNT1
InteractionGTF2H2C interactions

AR ESR1

7.08e-0450162int:GTF2H2C
InteractionTAF8 interactions

AR ESR1

7.08e-0450162int:TAF8
InteractionDDX46 interactions

MYO18A AR ESR1

7.09e-04227163int:DDX46
InteractionTEKT5 interactions

KLHL38 ESR1

7.37e-0451162int:TEKT5
InteractionPAGR1 interactions

AR ESR1

7.37e-0451162int:PAGR1
InteractionNCOA4 interactions

AR ESR1

7.37e-0451162int:NCOA4
InteractionRFC1 interactions

RB1 MSH6 ESR1

7.45e-04231163int:RFC1
InteractionSVIL interactions

MYO18A AR ESR1

7.64e-04233163int:SVIL
InteractionNKX3-1 interactions

AR ESR1

7.66e-0452162int:NKX3-1
InteractionUBTF interactions

RB1 AR ESR1

7.74e-04234163int:UBTF
InteractionGTF2F1 interactions

MYO18A AR ESR1

7.74e-04234163int:GTF2F1
InteractionGTF2H3 interactions

AR ESR1

7.95e-0453162int:GTF2H3
InteractionFOXK1 interactions

RB1 AR ESR1

8.13e-04238163int:FOXK1
InteractionJARID2 interactions

RB1 ESR1

8.26e-0454162int:JARID2
InteractionWIPI1 interactions

AR ESR1

8.56e-0455162int:WIPI1
InteractionVAV3 interactions

AR ESR1

8.56e-0455162int:VAV3
InteractionTMOD3 interactions

MYO18A AR ESR1

8.63e-04243163int:TMOD3
InteractionCDC27 interactions

RB1 AR ESR1

9.26e-04249163int:CDC27
InteractionRBM10 interactions

AR ESR1 ZNF317

9.70e-04253163int:RBM10
InteractionTBP interactions

RB1 AR ESR1

9.70e-04253163int:TBP
InteractionNPPA interactions

NPR3 ESR1

9.85e-0459162int:NPPA
InteractionMYL6 interactions

MYO18A AR ESR1

9.92e-04255163int:MYL6
InteractionARNT interactions

RB1 AR ESR1

9.92e-04255163int:ARNT
InteractionDSG2 interactions

MYO18A AR ESR1

1.00e-03256163int:DSG2
InteractionPBRM1 interactions

MSH6 AR ESR1

1.03e-03258163int:PBRM1
InteractionAFAP1 interactions

MYO18A ESR1

1.05e-0361162int:AFAP1
InteractionRNF40 interactions

RB1 AR ESR1

1.06e-03261163int:RNF40
InteractionTPM1 interactions

MYO18A AR ESR1

1.09e-03263163int:TPM1
InteractionMED23 interactions

RB1 AR ESR1

1.12e-03266163int:MED23
InteractionPAX5 interactions

KLHL38 RB1

1.16e-0364162int:PAX5
InteractionTTC5 interactions

AR ESR1

1.19e-0365162int:TTC5
InteractionMYO1B interactions

MYO18A AR ESR1

1.21e-03273163int:MYO1B
InteractionRAD9A interactions

MSH6 AR

1.23e-0366162int:RAD9A
InteractionTOM1L2 interactions

AR ESR1

1.23e-0366162int:TOM1L2
InteractionSMYD2 interactions

RB1 ESR1

1.27e-0367162int:SMYD2
InteractionCLP1 interactions

AR ESR1

1.27e-0367162int:CLP1
InteractionCORO2A interactions

MYO18A RB1

1.31e-0368162int:CORO2A
InteractionPPP1R12B interactions

MYO18A ESR1

1.31e-0368162int:PPP1R12B
InteractionINTS13 interactions

AR ESR1

1.34e-0369162int:INTS13
InteractionSUPT7L interactions

AR ESR1

1.34e-0369162int:SUPT7L
GeneFamilyIntermediate filament family orphans

IFFO2 IFFO1

7.34e-072162614
GeneFamilyNuclear hormone receptors

AR ESR1

8.43e-044916271
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF106 ZNF117 ZNF317

2.37e-0271816328
CoexpressionPUJANA_BREAST_CANCER_LIT_INT_NETWORK

RB1 MSH6 AR ESR1

4.76e-07101174M15356
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 IFFO1 MSH6 NPR3

6.45e-0718617437860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 IFFO1 MSH6 NPR3

6.45e-07186174baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 IFFO1 MSH6 NPR3

6.45e-0718617460830822d3de3147816693404fd03392e04c2b8e
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)|lymph-node_spleen / Manually curated celltypes from each tissue

MYO18A MSH6 ESR1

2.48e-051521734f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

RAPGEF3 NPR3 ESR1

3.06e-051631731a8c79903ed416f286ebe8a9922233affbc55d82
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

MYO18A CLN8 AR

3.78e-0517517329fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

MYO18A CLN8 AR

3.84e-05176173d6e660df92a3d7dd5732171ee623763faf108476
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ZNF106 AR ESR1

4.39e-0518417367164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

AR NPR3 ESR1

5.06e-05193173adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

KLHL38 ESR1

8.89e-0411717294f511dbf639b164c4b096195db312ecee3ee176
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|343B / Donor, Lineage, Cell class and subclass (all cells)

RB1 ZNF317

1.15e-031331728ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAPGEF3 ESR1

1.16e-03134172d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCellTCGA-Uvea|World / Sample_Type by Project: Shred V9

KLHL38 ZNF106

1.29e-03141172015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IFFO2 ADAM5

1.29e-031411727ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellTCGA-Breast|World / Sample_Type by Project: Shred V9

AR ESR1

1.45e-0315017208686ba1acac5c58667bf62e2af84c691d6bbdfb
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MSH6 ESR1

1.49e-031521726f9c343669883618cd9c1c8921a90c34d153f303
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

IFFO2 ZNF117

1.53e-03154172a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

IFFO2 NPR3

1.59e-031571722c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

IFFO2 RAPGEF3

1.63e-0315917297c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

IFFO2 RAPGEF3

1.63e-03159172fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

RAPGEF3 ZNF106

1.63e-03159172fb222c42f66901852b01cec073ec0732245ee973
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

IFFO2 AR

1.65e-031601728aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CLN8 AR

1.65e-0316017261f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CLN8 AR

1.65e-0316017234b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellCD8+_Memory_T_cell-FLU-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IFFO2 RAPGEF3

1.69e-0316217276f39935763848ea6e7917b2f9f1432c543063d9
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

NPR3 RNF175

1.73e-03164172c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

ESR1 ZNF117

1.77e-031661727e5852891714465c6228c9f955fd511ec79d0e02
ToppCellInfluenza_Severe-cDC|Influenza_Severe / Disease group and Cell class

NPR3 RNF175

1.77e-03166172b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

CLN8 AR

1.82e-03168172dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFFO1 NPR3

1.84e-031691723f738fc56bbc70dc77c9ba41025631f8264cd2b3
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEMP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NPR3 RNF175

1.84e-031691729a2fedee8ff90513bc2cbe2a65d07575ee8a0b70
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MYO18A RAPGEF3

1.84e-03169172c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MYO18A RAPGEF3

1.84e-03169172ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

MYO18A RAPGEF3

1.88e-0317117226b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

CLN8 AR

1.88e-0317117272c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR3 RNF175

1.88e-03171172fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL38 RNF175

1.90e-03172172f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RAPGEF3 NPR3

1.92e-031731723a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAPGEF3 NPR3

1.92e-0317317266488d01e03264fb193285470901c9c4182fbae8
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

ESR1 ZNF117

1.92e-03173172c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLHL38 RNF175

1.95e-03174172911eac6f6ec1e5e85348a7fe774243498388a810
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IFFO2 MSH6

1.99e-0317617291ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL38 RNF175

1.99e-03176172926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AR RNF175

2.01e-03177172709235694cc711b9b79690e23c94577b2ae06811
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AR RNF175

2.01e-031771727f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AR NPR3

2.01e-03177172fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

MYO18A NPR3

2.04e-03178172ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

MYO18A NPR3

2.04e-03178172804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NPR3 ESR1

2.06e-0317917214fc8ccb6b215063d747643f47d780d2b237eb67
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.06e-0317917208cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAPGEF3 NPR3

2.08e-0318017227e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MSH6 AR

2.08e-03180172886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

RAPGEF3 ESR1

2.10e-03181172a0549a8c2b5b30e91fae3052f398e48baa45d7ff
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

RAPGEF3 ESR1

2.10e-031811729b33f531c8ac776706ec7e2d47e95ba30b6ce13c
ToppCelldroplet-Heart-nan-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.10e-03181172859c40889ede2cbf374c4d2efbb72dc3bc6441f5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 NPR3

2.10e-031811725f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 NPR3

2.10e-03181172c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAPGEF3 NPR3

2.15e-03183172c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.15e-03183172c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.15e-0318317292eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.15e-03183172c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO18A AR

2.15e-031831723ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCelltumor_Lung-Myeloid_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

KLHL38 RB1

2.15e-031831727ef79365514e62dfc2e182e873e2b413d4f46b46
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RAPGEF3 NPR3

2.17e-03184172a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.17e-03184172f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO18A IFFO1

2.20e-03185172d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CLN8 AR

2.20e-03185172cc5152d3055375172bdf84f442b233c8fbd422b3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 NPR3

2.20e-0318517234fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CLN8 AR

2.20e-031851723091870a5bf8ecb963e560b47c8502bae367416c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 NPR3

2.20e-031851728816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

CLN8 AR

2.22e-03186172330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

CLN8 AR

2.22e-03186172916f2aeea4989ba7a29e071e348a51010f010223
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLN8 AR

2.22e-03186172fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

CLN8 AR

2.22e-0318617245f66619e45d590c7365a51782d4ac46b7d31fde
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CLN8 AR

2.22e-03186172fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

AR ESR1

2.24e-031871726bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellIIH-pDC-|IIH / Condition, Cell_class and T cell subcluster

CLN8 AR

2.24e-03187172ad87b146ea8dd9f695e722f8f0e8e1057c7f3167
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

CLN8 AR

2.24e-031871724d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellIIH-pDC|IIH / Condition, Cell_class and T cell subcluster

CLN8 AR

2.24e-031871725e59e9153a18bcfb5c8dc94599080216661de7ce
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAPGEF3 NPR3

2.24e-03187172e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYO18A CLN8

2.24e-03187172d3563bb087e476baea5b59389e4d34d0ff98cac5
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CLN8 AR

2.24e-03187172c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

RAPGEF3 IFFO1

2.27e-03188172c90669b51e1902fe7726555290c91c92a911df83
ToppCelldroplet-Fat-Scat-21m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.27e-031881728671fdbc4138e6f9559920779c98628ed80f0da3
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

RAPGEF3 NPR3

2.27e-03188172d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AR NPR3

2.29e-0318917228b502611829e4a24caff2562545c7db97686099
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AR NPR3

2.29e-031891723b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFFO1 ZNF117

2.29e-03189172bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

CLN8 AR

2.29e-031891726c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.31e-03190172dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellASK454-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CLN8 AR

2.31e-031901725cea6480f08253d7adf484e511d3fdfa96641268
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 AR

2.31e-031901729d5242759546be0089981ef1877e4ed5f81face5
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

CLN8 AR

2.31e-03190172dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 NPR3

2.31e-03190172d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

RAPGEF3 NPR3

2.31e-031901726e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

AR NPR3

2.31e-031901724f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

AR ESR1

2.31e-031901727dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellMS-pDC-|MS / Condition, Cell_class and T cell subcluster

CLN8 AR

2.31e-03190172f56ec302d556ace4f7609017a35c311cf43aa8a5
ToppCellMS-pDC|MS / Condition, Cell_class and T cell subcluster

CLN8 AR

2.31e-03190172f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSH6 NPR3

2.34e-031911724bfdf44d4402a42530d30c89d94946acdda4321b
Drugacetyl tert-butyl dimethylindan

AR ESR1

4.63e-072162ctd:C033118
Drug2-Chloroestradiol

AR ESR1

4.63e-072162CID000067343
Drug4-chloroestradiol

AR ESR1

4.63e-072162CID000067365
DrugI 357

AR ESR1

4.63e-072162CID000007442
Drugpyridate

AR ESR1

4.63e-072162ctd:C043100
Drugryodipine

AR ESR1

4.63e-072162ctd:C045912
DrugChlorobenzenes

AR ESR1

4.63e-072162ctd:D002722
Drug5-acetyl-1,1,2,6-tetramethyl-3-isopropylindane

AR ESR1

4.63e-072162ctd:C110695
DrugMelengestrol Acetate

AR ESR1

4.63e-072162ctd:D008552
Drugbutyl-methoxydibenzoylmethane

AR ESR1

4.63e-072162ctd:C474135
Drugcyoctol

AR ESR1

4.63e-072162CID000055994
Drugtemsirolimus

RB1 AR ESR1

5.71e-0724163ctd:C401859
Drug2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid

AR ESR1

1.39e-063162ctd:C101851
DrugNafoxidine

AR ESR1

1.39e-063162ctd:D009256
DrugDHTH

AR ESR1

1.39e-063162CID000160230
Drugp-tert-amylphenol

AR ESR1

1.39e-063162ctd:C019566
DrugBenzophenones

AR ESR1

1.39e-063162ctd:D001577
DrugChromans

AR ESR1

1.39e-063162ctd:D002839
Drug2,4,6-trichlorophenyl-4'-aminophenyl ether

AR ESR1

1.39e-063162ctd:C067259
Drug4-hydroxybenzophenone

AR ESR1

1.39e-063162ctd:C024292
DrugN-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide

RB1 AR ESR1

1.39e-0632163ctd:C451426
Druglycopene

RB1 MSH6 AR ESR1

2.56e-06143164ctd:C015329
Drugresibufogenin

MSH6 AR NPR3

2.56e-0639163CID000010063
Drug9,10-dihydrophenanthrene

AR ESR1

2.78e-064162CID000013058
Druglaurolactam

AR ESR1

2.78e-064162ctd:C474694
Drugchloropropylate

AR ESR1

2.78e-064162ctd:C004663
Drugphantolid

AR ESR1

2.78e-064162ctd:C033117
Drug4,4'-dihydroxybiphenyl

AR ESR1

2.78e-064162ctd:C027439
DrugLevonorgestrel

AR ESR1

2.78e-064162DB00367
Drug11-ketotestosterone

AR ESR1

2.78e-064162ctd:C003600
DrugFluoxymesterone

AR ESR1

2.78e-064162DB01185
Drug2-sec-butylphenol

AR ESR1

2.78e-064162ctd:C033932
Drugtestosterone decanoate

AR ESR1

2.78e-064162CID000155143
Drugisobutyl-4-hydroxybenzoate

AR ESR1

2.78e-064162ctd:C045922
Drugisofenphos

AR ESR1

2.78e-064162ctd:C035019
DrugAC1L1VK9

RB1 ESR1

2.78e-064162CID000036323
Drugethyl bromophos

AR ESR1

2.78e-064162ctd:C041062
Drugtaleranol

AR ESR1

2.78e-064162ctd:C028226
DrugPhenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester

AR ESR1

2.78e-064162ctd:D004849
Drugciclesonide

AR ESR1

2.78e-064162ctd:C120481
Drug2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol

RB1 ESR1

2.78e-064162ctd:C439584
Drugdichlofenthion

AR ESR1

2.78e-064162ctd:C011445
DrugAC1L1FBN

AR ESR1

2.78e-064162CID000003167
Drugchlorobenzilate

AR ESR1

4.62e-065162ctd:C004659
DrugAC1O5TI3

RB1 ESR1

4.62e-065162CID006440391
Drugtolclofos-methyl

AR ESR1

4.62e-065162ctd:C426783
Drug2,4',5-trichlorobiphenyl

AR ESR1

4.62e-065162ctd:C015550
Drugprothiophos

AR ESR1

4.62e-065162ctd:C032072
Drugisobutylparaben

AR ESR1

4.62e-065162ctd:C471067
DrugHexylresorcinol

AR ESR1

4.62e-065162ctd:D006604
Drugflucythrinate

AR ESR1

4.62e-065162ctd:C027975
Drug3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide

AR ESR1

4.62e-065162CID000115209
Drug3-benzylidene camphor

AR ESR1

4.62e-065162ctd:C511303
Drugzindoxifene

AR ESR1

4.62e-065162CID000065645
DrugLeptophos

AR ESR1

4.62e-065162ctd:D010773
Drug2,2',4,5'-tetrabromodiphenyl ether

AR ESR1

4.62e-065162ctd:C572625
Drughomosalate

AR ESR1

4.62e-065162ctd:C060446
DrugNorethynodrel

AR ESR1

4.62e-065162ctd:D009641
Drugethion

AR ESR1

4.62e-065162ctd:C100038
Drugletrozole

RB1 AR ESR1

4.83e-0648163ctd:C067431
Drug3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide

AR ESR1

6.93e-066162ctd:C101850
Drug2',3',4',5'-tetrachloro-4-biphenylol

AR ESR1

6.93e-066162ctd:C104006
Drugisopropyl 4,4'-dibromobenzilate

AR ESR1

6.93e-066162ctd:C038267
Drugequiguard

RB1 AR

6.93e-066162ctd:C498475
DrugDanazol

AR ESR1

6.93e-066162DB01406
Drugalpha-terthienyl

AR ESR1

6.93e-066162ctd:C019101
Drug2,6-di-tert-butyl-4-hydroxy-4-methyl-2,5-cyclohexadien-1-one

AR ESR1

6.93e-066162ctd:C038639
Drug3,5-di-tert-butyl-4-hydroxybenzaldehyde

AR ESR1

6.93e-066162ctd:C513957
DrugCB 1093

RB1 ESR1

6.93e-066162ctd:C103436
DrugEquilin

AR ESR1

6.93e-066162ctd:D004857
Drugtetralin

AR ESR1

6.93e-066162ctd:C095210
Drugdi-n-butyl phthalate

RB1 AR ESR1

8.14e-0657163CID000003026
DrugNadolol [42200-33-9]; Up 200; 13uM; PC3; HT_HG-U133A

IFFO1 NPR3 ESR1 ZNF117

8.58e-061941644021_UP
DrugDoxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A

RB1 CLN8 ZNF106 ZNF117

9.30e-061981643479_UP
Drugpendimethalin

AR ESR1

9.70e-067162ctd:C030856
Drug2,4,6-trichlorophenyl 4-nitrophenyl ether

AR ESR1

9.70e-067162ctd:C010422
Drug2,2-di(4-methacryloxyphenyl)propane

AR ESR1

9.70e-067162ctd:C002462
DrugDIBA-1

RB1 ESR1

9.70e-067162ctd:C100805
Drugethyl myristate

AR ESR1

9.70e-067162ctd:C032396
Drugboldenone undecylenate

AR ESR1

9.70e-067162ctd:C001371
Druglacidipine

AR ESR1

9.70e-067162ctd:C060285
Drugoctyldimethyl-p-aminobenzoic acid

AR ESR1

9.70e-067162CID000042851
Drugatamestane

AR ESR1

9.70e-067162CID000057050
Druglercanidipine

AR ESR1

9.70e-067162ctd:C060343
Drug3-phenoxybenzoic acid

AR ESR1

9.70e-067162ctd:C017618
Druglead thiocyanate

AR ESR1

9.70e-067162CID000011616
Drugdi-n-octyl phthalate

AR ESR1

1.29e-058162ctd:C010715
Drugaroclor 1221

AR ESR1

1.29e-058162ctd:C032739
DrugNisoldipine

AR ESR1

1.29e-058162ctd:D015737
Drug4-cumylphenol

AR ESR1

1.29e-058162ctd:C516284
Drugtolclofos-methyl

AR ESR1

1.29e-058162CID000091664
DrugColchicine

RB1 CLN8 MSH6 ESR1

1.46e-05222164ctd:D003078
Drugmethoxychlor

RB1 AR ESR1

1.65e-0572163CID000004115
Drugpirarubicin

AR ESR1

1.66e-059162ctd:C027260
DrugAndrostenediol

AR ESR1

1.66e-059162ctd:D015114
Druggalaxolide

AR ESR1

1.66e-059162ctd:C033119
DrugOxymetholone

AR ESR1

1.66e-059162ctd:D010110
Drug4-phenylphenol

AR ESR1

1.66e-059162ctd:C019046
DrugGoserelin

AR ESR1

1.66e-059162ctd:D017273
Drugpropamocarb

AR ESR1

1.66e-059162CID000032490
Diseaseleukemia

MSH6 AR ESR1

3.37e-0655163C0023418
Diseaseprostatic hypertrophy (implicated_via_orthology)

AR ESR1

4.13e-066162DOID:11132 (implicated_via_orthology)
DiseaseProstatic Intraepithelial Neoplasias

AR ESR1

1.51e-0511162C0282612
Diseaseprostate cancer (is_implicated_in)

RB1 AR ESR1

3.28e-05117163DOID:10283 (is_implicated_in)
Diseasein situ carcinoma (is_marker_for)

RB1 ESR1

5.75e-0521162DOID:8719 (is_marker_for)
DiseaseNeoplasm of the genitourinary tract

RB1 AR

7.56e-0524162cv:C0042065
DiseasePilocytic Astrocytoma

AR ESR1

8.21e-0525162C0334583
DiseaseCerebral Astrocytoma

AR ESR1

8.21e-0525162C0750935
DiseaseIntracranial Astrocytoma

AR ESR1

8.21e-0525162C0750936
DiseaseAstrocytoma

AR ESR1

8.21e-0525162C0004114
DiseaseJuvenile Pilocytic Astrocytoma

AR ESR1

8.21e-0525162C0280783
DiseaseDiffuse Astrocytoma

AR ESR1

8.21e-0525162C0280785
DiseaseGrade I Astrocytoma

AR ESR1

8.21e-0525162C1704230
DiseaseSubependymal Giant Cell Astrocytoma

AR ESR1

8.21e-0525162C0205768
DiseaseMixed oligoastrocytoma

AR ESR1

8.21e-0525162C0547065
DiseaseChildhood Cerebral Astrocytoma

AR ESR1

8.21e-0525162C0338070
DiseaseGemistocytic astrocytoma

AR ESR1

8.89e-0526162C0334581
DiseaseProtoplasmic astrocytoma

AR ESR1

8.89e-0526162C0334580
DiseaseFibrillary Astrocytoma

AR ESR1

8.89e-0526162C0334582
DiseaseAnaplastic astrocytoma

AR ESR1

9.60e-0527162C0334579
DiseaseSubfertility, Female

AR ESR1

1.03e-0428162C0341869
DiseaseSterility, Postpartum

AR ESR1

1.03e-0428162C0038279
DiseaseFemale sterility

AR ESR1

1.03e-0428162C0917730
DiseaseFemale infertility

AR ESR1

1.03e-0428162C0021361
DiseaseNeoplasm of uncertain or unknown behavior of ovary

MSH6 ESR1

1.11e-0429162C0496920
DiseaseOvarian Carcinoma

MSH6 ESR1

1.19e-0430162C0029925
Diseaseendometrial cancer (is_implicated_in)

MSH6 AR

1.72e-0436162DOID:1380 (is_implicated_in)
Diseaseductal carcinoma in situ (is_marker_for)

RB1 AR

2.02e-0439162DOID:0060074 (is_marker_for)
DiseaseNeoplasm Recurrence, Local

AR ESR1

2.02e-0439162C0027643
DiseaseBreast adenocarcinoma

RB1 ESR1

2.23e-0441162C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

RB1 ESR1

2.23e-0441162C0496956
DiseaseProstatic Neoplasms

RB1 AR NPR3 ESR1

2.80e-04616164C0033578
DiseaseMalignant neoplasm of prostate

RB1 AR NPR3 ESR1

2.80e-04616164C0376358
DiseaseMale sterility

AR ESR1

3.06e-0448162C0917731
DiseaseMale infertility

AR ESR1

3.06e-0448162C0021364
DiseaseSubfertility, Male

AR ESR1

3.06e-0448162C0848676
Diseaseaortic measurement

KLHL38 NPR3 ESR1

3.14e-04251163EFO_0020865
DiseaseEndometrial Neoplasms

MSH6 ESR1

4.48e-0458162C0014170
Diseaseacute kidney failure (biomarker_via_orthology)

RB1 AR

4.95e-0461162DOID:3021 (biomarker_via_orthology)
Diseasebreast carcinoma (is_marker_for)

MSH6 ESR1

5.79e-0466162DOID:3459 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MYCFEMHCKHVRFLM

ADAM5

336

Q6NVV9
YAKMGEMMLALFRHH

NPR3

181

P17342
RDRHLDQIMMCSMYG

RB1

696

P06400
HMSNKGMEHLYSMKC

ESR1

516

P03372
EKVMHMFKGCRREDM

MYO18A

456

Q92614
MHKSRMYSQCVRMRH

AR

776

P10275
MMEARCRKMAHISKY

MSH6

491

P52701
MNRHLHEYMEMCSMK

IFFO1

491

Q0D2I5
HEYMEMCSMKRGLDV

IFFO1

496

Q0D2I5
RHLHEYMEMCSMKRG

IFFO2

451

Q5TF58
CHLLHYMMIMSLHRC

OR1P1

141

Q8NH06
LMIHMFHCRMVLTYH

CLN8

196

Q9UBY8
KMRMMARAARMLHHC

RAPGEF3

841

O95398
MYKMHRGHDSMHVEM

RNF175

41

Q8N4F7
MKRHEMVAKHLVMFY

ZNF117

1

Q03924
QHMSMYDGRKMHECH

ZNF317

211

Q96PQ6
YGGHKDMIMCMTIHK

ZNF106

1776

Q9H2Y7
DMKDRRMHHGATVMG

KLHL38

506

Q2WGJ6