Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway

GRB10 TMEM131L JADE1 LZTS2 NKD1

1.60e-05195345GO:0030178
GeneOntologyBiologicalProcessnegative regulation of canonical Wnt signaling pathway

TMEM131L JADE1 LZTS2 NKD1

1.16e-04154344GO:0090090
GeneOntologyCellularComponentspectrin

SPTA1 SPTAN1

9.18e-059342GO:0008091
GeneOntologyCellularComponentcuticular plate

SPTA1 SPTAN1

1.98e-0413342GO:0032437
MousePhenoabnormal cortical ventricular zone cell density

SMARCA1 SPTAN1

3.87e-062282MP:0014559
DomainEF-hand_Ca_insen

SPTA1 SPTAN1

4.52e-056332IPR014837
DomainEFhand_Ca_insen

SPTA1 SPTAN1

4.52e-056332PF08726
DomainSpectrin_alpha_SH3

SPTA1 SPTAN1

3.13e-0415332IPR013315
DomainEF_HAND_2

NKD1 PPEF1 SPTA1 SPTAN1

7.04e-04231334PS50222
DomainEF_hand_dom

NKD1 PPEF1 SPTA1 SPTAN1

7.15e-04232334IPR002048
DomainSpectrin

SPTA1 SPTAN1

7.48e-0423332PF00435
Domain-

NKD1 PPEF1 SPTA1 SPTAN1

1.11e-032613341.10.238.10
DomainSpectrin_repeat

SPTA1 SPTAN1

1.19e-0329332IPR002017
DomainSNF2_N

SMARCA1 SRCAP

1.45e-0332332PF00176
DomainSNF2_N

SMARCA1 SRCAP

1.45e-0332332IPR000330
DomainPlexin_repeat

SEMA3D PLXDC1

1.45e-0332332IPR002165
DomainPSI

SEMA3D PLXDC1

1.45e-0332332PF01437
DomainSpectrin/alpha-actinin

SPTA1 SPTAN1

1.45e-0332332IPR018159
DomainSPEC

SPTA1 SPTAN1

1.45e-0332332SM00150
DomainEF-hand-dom_pair

NKD1 PPEF1 SPTA1 SPTAN1

1.57e-03287334IPR011992
DomainEFh

PPEF1 SPTA1 SPTAN1

2.69e-03158333SM00054
DomainPSI

SEMA3D PLXDC1

2.98e-0346332SM00423
DomainEF_Hand_1_Ca_BS

NKD1 PPEF1 SPTAN1

3.59e-03175333IPR018247
DomainEF_HAND_1

NKD1 PPEF1 SPTAN1

5.50e-03204333PS00018
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTA1 SPTAN1

1.35e-0410252MM15112
Pubmed

αII-spectrin regulates invadosome stability and extracellular matrix degradation.

SPTA1 SPTAN1

9.28e-07234225830635
Pubmed

Ankyrin-independent membrane protein-binding sites for brain and erythrocyte spectrin.

SPTA1 SPTAN1

2.78e-0633422971657
Pubmed

Mapping of a spectrin-binding domain of human erythrocyte membrane protein 4.2.

SPTA1 SPTAN1

5.56e-06434212049649
Pubmed

Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.

SPTA1 SPTAN1

5.56e-0643429593709
Pubmed

Disruption of spectrin-like cytoskeleton in differentiating keratinocytes by PKCδ activation is associated with phosphorylated adducin.

SPTA1 SPTAN1

5.56e-06434222163289
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTA1 SPTAN1

5.56e-06434221566095
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTA1 SPTAN1

5.56e-06434212820899
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTA1 SPTAN1

5.56e-0643423862089
Pubmed

Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex.

SPTA1 SPTAN1

5.56e-06434210551855
Pubmed

Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.

SPTA1 SPTAN1

5.56e-06434212571280
Pubmed

RGD-containing ankyrin externalized onto the cell surface triggers αVβ3 integrin-mediated erythrophagocytosis.

SPTA1 SPTAN1

9.26e-06534221406181
Pubmed

Spectrin interacts with EVL (Enabled/vasodilator-stimulated phosphoprotein-like protein), a protein involved in actin polymerization.

SPTA1 SPTAN1

9.26e-06534216336193
Pubmed

Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.

SPTA1 SPTAN1

9.26e-0653423027087
Pubmed

Chromosomal location of three spectrin genes: relationship to the inherited hemolytic anemias of mouse and man.

SPTA1 SPTAN1

1.94e-0573423186715
Pubmed

Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms.

SPTA1 SPTAN1

1.94e-05734221752934
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

SPTA1 SPTAN1

4.15e-051034222159418
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

ZWILCH SRCAP

1.41e-041834225363768
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTA1 SPTAN1

1.41e-041834212119179
Pubmed

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.

SPTA1 SPTAN1

1.74e-042034218723693
Pubmed

The small GTPase Rac1 regulates auditory hair cell morphogenesis.

SPTA1 SPTAN1

2.32e-042334220016102
Pubmed

Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.

SPTA1 SPTAN1

2.74e-042534220696915
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTA1 SPTAN1

2.74e-04253428493579
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

USP25 BCAN TDRD6 SPTA1 SPTAN1

3.24e-0462134522794259
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

GRB10 LRP1B

4.52e-043234225189868
Pubmed

alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus.

SPTA1 SPTAN1

5.10e-043434216889989
Pubmed

RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

SIN3B SRCAP

5.72e-043634217573780
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

NOL4 PTCHD1 JADE1 LZTS2

6.20e-0440234424722188
Pubmed

Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.

SPTA1 SPTAN1

6.72e-04393421676977
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

GRB10 PLEKHJ1 NOL4 MOXD1 JADE1 SPTAN1

6.96e-04112434621900206
CytobandXq25

SMARCA1 XPNPEP2

4.29e-0441342Xq25
GeneFamilyEF-hand domain containing|Spectrins

SPTA1 SPTAN1

3.24e-0572321113
GeneFamilyEF-hand domain containing

NKD1 PPEF1 SPTA1 SPTAN1

1.55e-04219234863
GeneFamilyAdenosine receptors|V-set domain containing

SEMA3D BCAN

1.81e-02163232590
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GRB10 PLEKHJ1

2.79e-02206232682
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 PTCHD1 LRP1B TGDS

6.90e-06162344ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D175|Adult / Lineage, Cell type, age group and donor

GRB10 PLXDC1 LRP1B SPTA1

9.79e-06177344c9f269765c7d5d29caab75910e51645606ed562e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L MOXD1 NKD1 PLXDC1

1.29e-0519034470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NOL4 SEMA3D NKD1

1.29e-05190344f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NOL4 SEMA3D NKD1

1.29e-05190344562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

NOL4 NKD1 CLDN23

2.35e-041583438d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCelldroplet-Heart-nan-18m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3D NKD1 GAA

2.71e-041663439adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTCHD1 MOXD1 LRP1B

3.22e-041763430710689e66deba179b0a8038cdd56b4834984f12
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SMARCA1 TDRD6 PLXDC1

3.27e-041773433d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 GRB10 PTCHD1

3.27e-041773431dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

MOXD1 BCAN NKD1

3.27e-041773437617270f49cd6b7ba66db72d20560cee985012b2
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

MOXD1 BCAN NKD1

3.27e-041773438220cc2fc0ee8764a67a3be51d75248be2453040
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 GRB10 PTCHD1

3.27e-04177343426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTCHD1 MOXD1 LRP1B

3.33e-041783436f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

3.44e-0418034308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

3.44e-041803439b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

3.50e-041813439e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTCHD1 MOXD1 LRP1B

3.50e-041813439de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

3.50e-04181343c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

3.50e-04181343c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTCHD1 MOXD1 LRP1B

3.55e-04182343cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 GRB10 PTCHD1

3.55e-041823435b2bad38c723cd64a7fe7f2dcd361708014c8cfe
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 GRB10 PTCHD1

3.55e-04182343de90bf587a73973a8b1458c9cd366c274b72ef9e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRP1B SPTA1

3.67e-04184343ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRP1B SPTA1

3.67e-041843432cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 LRP1B SPTA1

3.67e-041843432b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3D ZWILCH PPEF1

3.67e-04184343d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 GRB10 BCAN

3.73e-041853434e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SEMA3D MOXD1 LRP1B

3.79e-041863438915436d09775f2828a7678af203b1082b36e21c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NKD1 PLXDC1

3.85e-04187343530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NKD1 PLXDC1

3.85e-04187343ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

XPNPEP2 NKD1 PLXDC1

3.91e-04188343db0652f000d459493321b53239326706eace598c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PTCHD1 NKD1

3.91e-04188343b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SEMA3D PTCHD1 NKD1

3.91e-0418834334e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOXD1 NKD1 PLXDC1

3.91e-04188343d534ed9870405a3c1075962308f72b460aed17bf
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SEMA3D PTCHD1 NKD1

3.97e-041893436b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NKD1 PLXDC1

3.97e-04189343fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 WEE1 GAA

3.97e-04189343533685a921a65d84107d8d33c43b4fffde019143
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PTCHD1 NKD1

3.97e-041893432cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 WEE1 GAA

3.97e-04189343dca56ab02bf0505f9a352ff907edaef30906d854
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XPNPEP2 NKD1 PLXDC1

3.97e-0418934309dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XPNPEP2 NKD1 PLXDC1

3.97e-041893437b6cb745c0a637d6addc105a79059ed488fced39
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PTCHD1 NKD1

3.97e-04189343127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

XPNPEP2 NKD1 PLXDC1

4.03e-0419034352213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 WEE1 GAA

4.03e-04190343a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB10 LZTS2 GAA

4.03e-0419034396a9756cad5468a12591021e6d661ed269b5b3d9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SEMA3D MOXD1 LRP1B

4.09e-04191343fa380a8752de158974b2ae5e741573439719cc0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.09e-04191343107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.09e-04191343bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.15e-04192343bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB10 LZTS2 GAA

4.15e-04192343959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCAN PLXDC1 LRP1B

4.15e-041923438ad6678df89175c5a4a835c8566f1552df3c996e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NKD1 PLXDC1

4.15e-0419234324e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 WEE1 GAA

4.15e-0419234303dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.15e-041923430ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

4.15e-04192343deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCAN PLXDC1 LRP1B

4.15e-041923432f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

4.22e-04193343fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA3D MOXD1 NKD1

4.28e-0419434360622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 WEE1 GAA

4.28e-04194343c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PTCHD1 NKD1

4.28e-041943435c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.28e-04194343ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PTCHD1 NKD1

4.28e-04194343ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.28e-04194343cf0244a29934e515446ac917d3c30672b460fb04
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SEMA3D MOXD1 LRP1B

4.28e-0419434385e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L MOXD1 NKD1

4.35e-04195343edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.35e-04195343d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.41e-04196343802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRB10 MOXD1 WEE1

4.41e-04196343b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L NKD1 PLXDC1

4.41e-04196343b8759e6231e0254797d6c30930407b79440c57bb
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3D MOXD1 LRP1B

4.41e-041963439830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 NKD1 PLXDC1

4.41e-04196343fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MOXD1 BCAN PPEF1

4.48e-04197343bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MOXD1 BCAN NKD1

4.48e-0419734344673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell(5)_Fibroblasts-(5)_Fibroblast-E|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SEMA3D XPNPEP2 PLXDC1

4.48e-041973439b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3D MOXD1 NKD1

4.54e-041983431e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3D MOXD1 LRP1B

4.54e-0419834322e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTCHD1 JADE1 LRP1B

4.54e-04198343cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRB10 MOXD1 WEE1

4.61e-04199343cfe6f881a86607544e1413ef38e4b6797ef1a61c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Glia_progenitor_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MOXD1 BCAN TGDS

4.68e-042003430b91c8da21ba488109f15c9b927c1dcaf8c6b0ae
ToppCellNeuronal-Excitatory-eF(C1QL3)|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTCHD1 MOXD1 LRP1B

4.68e-042003437668ae7ed550583ab59e419c5c9bb9f2d7e8e0d5
ToppCellNeuronal-Excitatory-eF(C1QL3)----L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTCHD1 MOXD1 LRP1B

4.68e-0420034344f0278cb0e4ffcda4af3719d7f5819a10929b9f
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

PTCHD1 LRP1B SPTAN1

4.68e-04200343e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCellNeuronal-Excitatory-eF(C1QL3)---|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTCHD1 MOXD1 LRP1B

4.68e-0420034323da7790e09575b2ca909ed16806b44223bf1017
ToppCellNeuronal-Excitatory-eF(C1QL3)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTCHD1 MOXD1 LRP1B

4.68e-0420034391f3df1c5a661ff703835f58a35cee93f18eb15c
ToppCellNeuronal-Excitatory-eF(C1QL3)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTCHD1 MOXD1 LRP1B

4.68e-042003432e2b1d252972b702ade25526ec8461bf613d81b0
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

SIN3B SRCAP

1.38e-0349332DOID:0060037 (implicated_via_orthology)
Diseaseasthma, response to diisocyanate

TMEM131L NOL4 LRP1B

3.07e-03261333EFO_0006995, MONDO_0004979
Diseasesuntan

PRDM7 TGDS

5.94e-03103332EFO_0004279
Diseasemood instability measurement

LRP1B CLDN23

9.03e-03128332EFO_0008475
Diseaseplatelet component distribution width

TMEM131L WEE1 GAA SPTA1

9.65e-03755334EFO_0007984

Protein segments in the cluster

PeptideGeneStartEntry
DNTYSRELFEEMRWT

B3GAT3

196

O94766
SAEDMELRWYRCQPS

BTNL10

61

A8MVZ5
QEEDRAWMYSRTQDC

C13orf42

71

A0A1B0GVH6
CDVSMEEDSRQEWTF

NKD1

126

Q969G9
RRSWEEAETQCRMYG

BCAN

706

Q96GW7
IYNEDMICWIESRES

LRP1B

241

Q9NZR2
EATMCQAYEERQRHW

LZTS2

351

Q9BRK4
QWNDLDYMDSRRDFT

GAA

401

P10253
AEDEQTRTCWMTAFR

GRB10

381

Q13322
YQGLWDMCREQSSRE

CLDN23

46

Q96B33
ESEQDMRDRWDYVDS

PPEF1

86

O14829
ADMEEYIWENSSSER

MRPS35

246

P82673
DRGNSENVDWYDVRM

TDRD6

571

O60522
MEYSAVFWERCNELQ

SMARCA1

896

P28370
CTDAMRENWISLRYA

TMEM131L

1021

A2VDJ0
LNDMVAERWESSFCD

PTCHD1

221

Q96NR3
SSEEQCQEWMEALRR

PLEKHJ1

91

Q9NW61
CQEWMEALRRASYEF

PLEKHJ1

96

Q9NW61
SSANWMRYVNCARDD

PRDM7

311

Q9NQW5
ETSYQWKAERCMADE

SIN3B

936

O75182
DSVCRYDLNDMDAAW

JADE1

136

Q6IE81
CEEMQWLSADFAQER

SRCAP

141

Q6ZRS2
MESERDMYRQFQDWC

NOL4

1

O94818
SLDQYCEQMWHREKR

SEMA3D

726

O95025
SESEMENWVDYVNDR

TGDS

281

O95455
DCAERTLYWDVMLEN

ZNF684

26

Q5T5D7
RTYWNDSCGEDMEAS

WEE1

256

P30291
MWERLNCAAEDFYSR

ZWILCH

1

Q9H900
TECRYNTKDRAEMTW

MOXD1

441

Q6UVY6
HRDCEQAENWMAARE

SPTAN1

1451

Q13813
AVEDMRNRWCSYLGQ

USP25

981

Q9UHP3
FYRDSEQVDSWMSRQ

SPTA1

481

P02549
RYWTQAERQMDCNWE

XPNPEP2

116

O43895
DRYRQEWMDYGCAQE

PLXDC1

336

Q8IUK5
YWDNPMVVCRENSDT

TBCCD1

441

Q9NVR7
CQRQYDARVDLWSMG

ULK3

186

Q6PHR2