Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentB cell receptor complex

LIME1 IGHM

1.56e-048502GO:0019815
DomainLRRC37AB_C

LRRC37A3 LRRC37B

4.20e-054502PF14914
DomainLRRC37_N

LRRC37A3 LRRC37B

4.20e-054502IPR032754
DomainLRRC37AB_C

LRRC37A3 LRRC37B

4.20e-054502IPR029423
DomainLRRC37

LRRC37A3 LRRC37B

4.20e-054502PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37B

4.20e-054502IPR015753
DomainBRCT

MDC1 TP53BP1

1.17e-0319502PF00533
DomainBRCT

MDC1 TP53BP1

1.57e-0322502SM00292
Domain-

MDC1 TP53BP1

1.71e-03235023.40.50.10190
DomainBRCT

MDC1 TP53BP1

2.19e-0326502PS50172
DomainBRCT_dom

MDC1 TP53BP1

2.54e-0328502IPR001357
DomainZnf-RING_LisH

RC3H2 RC3H1

3.73e-0334502IPR027370
Domainzf-RING_UBOX

RC3H2 RC3H1

3.73e-0334502PF13445
Domain-

RC3H2 RC3H1

5.13e-03405024.10.1000.10
DomainZnF_C3H1

RC3H2 RC3H1

7.32e-0348502SM00356
DomainZF_RING_1

RC3H2 MYCBP2 RC3H1 MAP3K1

7.58e-03291504PS00518
Domainzf-CCCH

RC3H2 RC3H1

7.62e-0349502PF00642
DomainZF_RING_2

RC3H2 MYCBP2 RC3H1 MAP3K1

8.22e-03298504PS50089
DomainRING

RC3H2 MYCBP2 RC3H1 MAP3K1

8.90e-03305504SM00184
DomainZnf_CCCH

RC3H2 RC3H1

1.06e-0258502IPR000571
DomainZF_C3H1

RC3H2 RC3H1

1.06e-0258502PS50103
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

LIMA1 PTPN14 MRTFB ALMS1 MYCBP2 RPAP3 MDC1 CUX1 TP53BP1

9.62e-0854951938280479
Pubmed

Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.

RC3H2 RC3H1 IGHM

1.65e-07851329246441
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PASK MRTFB ALMS1 ZNF608 MYCBP2 SETBP1

9.69e-0722551612168954
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FNBP1 MRTFB FAM120A ZNF608 MYCBP2 RRP36 GALNT11 SETBP1 FECH DYNC2I1 SHROOM2 CUX1

1.22e-061489511228611215
Pubmed

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.

MDC1 TP53BP1

2.11e-06251217546051
Pubmed

The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.

MDC1 TP53BP1

2.11e-06251222677490
Pubmed

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.

MDC1 TP53BP1

2.11e-06251218158901
Pubmed

[Expression of DNA damage checkpoint mediator 1 and p53-binding protein 1 in human esophageal cancer cell lines TE-1, TE-13, and Eca109].

MDC1 TP53BP1

2.11e-06251217884766
Pubmed

The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.

MDC1 TP53BP1

2.11e-06251218986980
Pubmed

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.

MDC1 TP53BP1

2.11e-06251216009723
Pubmed

Structure of human Roquin-2 and its complex with constitutive-decay element RNA.

RC3H2 RC3H1

2.11e-06251226249698
Pubmed

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells.

MDC1 TP53BP1

2.11e-06251225976740
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MRTFB RESF1 ALMS1 ZNF608 MYCBP2 RPAP3 CUX1

2.53e-0641851734709266
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

RESF1 ALMS1 ZNF608 RRP36 RC3H1

2.98e-0615251538360978
Pubmed

Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants.

MDC1 TP53BP1

6.32e-06351228397142
Pubmed

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.

MDC1 TP53BP1

6.32e-06351218504301
Pubmed

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

MDC1 TP53BP1

6.32e-06351214695167
Pubmed

Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.

RC3H2 RC3H1

6.32e-06351230232334
Pubmed

Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.

RC3H2 RC3H1

6.32e-06351223583642
Pubmed

Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

MDC1 TP53BP1

6.32e-06351222860035
Pubmed

Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.

RC3H2 RC3H1

6.32e-06351228188245
Pubmed

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

MDC1 TP53BP1

6.32e-06351224324146
Pubmed

Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks.

MDC1 TP53BP1

6.32e-06351230668775
Pubmed

Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms.

IQSEC1 ARHGEF11

6.32e-06351220613766
Pubmed

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.

RC3H2 RC3H1

6.32e-06351225026077
Pubmed

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

MDC1 TP53BP1

6.32e-06351220421415
Pubmed

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

MDC1 TP53BP1

6.32e-06351219001859
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

USP30 PTPN14 FAM120A ALMS1 MYCBP2 RPAP3 POLE FECH DYNC2I1 RANBP6 CUX1

8.76e-061496511132877691
Pubmed

Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production.

IGHM MAP3K1

1.26e-05451217143273
Pubmed

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.

RC3H2 RC3H1

1.26e-05451225697406
Pubmed

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage.

MDC1 TP53BP1

1.26e-05451217925396
Pubmed

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.

MDC1 TP53BP1

1.26e-05451216901786
Pubmed

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

MDC1 TP53BP1

1.26e-05451218664457
Pubmed

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation.

RC3H2 RC3H1

1.26e-05451231636267
Pubmed

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.

MDC1 TP53BP1

1.26e-05451221293379
Pubmed

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.

SOX11 CDH2

1.26e-05451220847309
Pubmed

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.

MDC1 TP53BP1

1.26e-05451212551934
Pubmed

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

MDC1 TP53BP1

1.26e-05451212556884
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FNBP1 PASK LIMA1 MYCBP2 MDC1 IQSEC1 TP53BP1 PHC2

1.59e-0577451815302935
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIAA1210 MRTFB ZNF608 ATAD2B

1.63e-0510351410574462
Pubmed

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks.

MDC1 TP53BP1

2.10e-05551218678890
Pubmed

Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.

RC3H2 RC3H1

2.10e-05551227010430
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

FAM120A EML5 RPAP3 POLE DYNC2I1

2.31e-0523251525515538
Pubmed

The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1.

MDC1 TP53BP1

3.15e-05651226734725
Pubmed

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

MDC1 TP53BP1

3.15e-05651218001824
Pubmed

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

MDC1 TP53BP1

3.15e-05651231217297
Pubmed

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.

RC3H2 RC3H1

3.15e-05651234471108
Pubmed

Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth.

CDH2 CUX1

3.15e-05651231909712
Pubmed

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

MDC1 TP53BP1

3.15e-05651221852011
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PASK PTPN14 RESF1 FAM120A EML5 ALMS1 ZNF608 FECH IQSEC1

3.16e-05111651931753913
Pubmed

Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.

RC3H2 RC3H1

4.41e-05751234811541
Pubmed

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

MDC1 TP53BP1

4.41e-05751218001825
Pubmed

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.

MDC1 TP53BP1

4.41e-05751216872911
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

MRTFB ALMS1 RPAP3

5.22e-054951331762063
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

LIMA1 ALMS1 RPAP3 MDC1 CUX1 MAP3K1 TP53BP1

5.29e-0567051722990118
Pubmed

DNA damage response in microcephaly development of MCPH1 mouse model.

CUX1 TP53BP1

5.87e-05851223683352
Pubmed

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.

RC3H2 RC3H1

5.87e-05851225282160
Pubmed

Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans.

CDH2 CUX1

5.87e-05851224781755
Pubmed

Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.

RC3H2 RC3H1

5.87e-05851229352114
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

LIMA1 FAM120A MYCBP2 IQSEC1 ARHGEF11 CDH2 CUX1 TP53BP1

7.44e-0596351828671696
Pubmed

The histone demethylase LSD1/KDM1A promotes the DNA damage response.

MDC1 TP53BP1

7.54e-05951224217620
Pubmed

Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.

IKZF2 MYH7B

7.54e-05951222638570
Pubmed

Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.

CUX1 TP53BP1

7.54e-05951231541646
Pubmed

Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism.

LIMA1 CDH2

9.42e-051051235105859
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37B

9.42e-051051223064749
Pubmed

Seven genes from human chromosome 18 map to chromosome 24 in the bovine.

CDH2 GRP

9.42e-05105128697804
Pubmed

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.

CDH2 CUX1

9.42e-051051225402856
Pubmed

SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex.

CDH2 CUX1

9.42e-051051225088364
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ENAM LIMA1 SETBP1 MDC1 LRRC37B PHC2

1.03e-0451351625798074
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

PASK LIMA1 RPAP3 TP53BP1

1.07e-0416751425659891
Pubmed

Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.

MYCBP2 CDH2

1.15e-041151225143387
Pubmed

Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

CDH2 CUX1

1.15e-041151225232112
Pubmed

MDC1 is a mediator of the mammalian DNA damage checkpoint.

MDC1 TP53BP1

1.15e-041151212607005
Pubmed

Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.

CDH2 CUX1

1.15e-041151234999833
Pubmed

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.

RC3H2 RC3H1

1.15e-041151223583643
Pubmed

RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution.

CDH2 CUX1

1.15e-041151237085665
Pubmed

Identification of new high affinity targets for Roquin based on structural conservation.

RC3H2 RC3H1

1.15e-041151230295819
Pubmed

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.

MDC1 TP53BP1

1.15e-041151220081839
Pubmed

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.

CUX1 TP53BP1

1.15e-041151233087478
Pubmed

Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.

CDH2 CUX1

1.15e-041151232245946
Pubmed

RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination.

CDH2 CUX1

1.38e-041251235979738
Pubmed

Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization.

SOX11 CUX1

1.63e-041351233579706
Pubmed

Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

CDH2 CUX1

1.63e-041351226903504
Pubmed

Cis-regulatory control of corticospinal system development and evolution.

SOX11 CUX1

1.63e-041351222678282
Pubmed

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

MDC1 TP53BP1

1.63e-041351229499138
Pubmed

IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.

IGHM TP53BP1

1.63e-041351228137874
Pubmed

Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex.

CDH2 CUX1

1.63e-041351227390776
Pubmed

Interaction network of human early embryonic transcription factors.

RESF1 ALMS1 ZNF608 MDC1 CDH2

1.63e-0435151538297188
Pubmed

Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing.

SOX11 ZNF608

1.90e-041451221873192
Pubmed

FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.

MDC1 TP53BP1

1.90e-041451226123487
Pubmed

Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors.

SKOR2 TP53BP1

1.90e-041451228893945
Pubmed

FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons.

SOX11 CUX1

1.90e-041451235613274
Pubmed

Human transcription factor protein interaction networks.

LIMA1 RESF1 FAM120A ALMS1 ZNF608 RC3H1 MDC1 CUX1 TP53BP1

2.08e-04142951935140242
Pubmed

C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.

CDH2 CUX1

2.19e-041551227111087
Pubmed

Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells.

CDH2 CUX1

2.19e-041551228552558
Pubmed

Loss of Lgl1 Disrupts the Radial Glial Fiber-guided Cortical Neuronal Migration and Causes Subcortical Band Heterotopia in Mice.

CDH2 CUX1

2.19e-041551230597194
Pubmed

Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin.

CDH2 CUX1

2.19e-041551225988834
Pubmed

Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon.

CDH2 CUX1

2.19e-041551225100583
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PTPN14 MRTFB FAM120A ALMS1 RPAP3 DYNC2I1 ARHGEF11

2.36e-0485351728718761
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LIMA1 PTPN14 RESF1 ALMS1 MYCBP2 IQSEC1 NR3C2

2.49e-0486151736931259
InteractionTRIM66 interactions

PASK PTPN14 FAM120A ALMS1 ZNF608 IQSEC1

1.27e-05205516int:TRIM66
Cytoband18q21.1

SKOR2 SETBP1

8.29e-043851218q21.1
CytobandEnsembl 112 genes in cytogenetic band chr18q21

SKOR2 FECH GRP

1.56e-03205513chr18q21
Cytoband9q34

FNBP1 RC3H2

1.67e-03545129q34
GeneFamilyZinc fingers CCCH-type

RC3H2 RC3H1

1.53e-033530273
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

FNBP1 RIPOR2 RESF1 IGHM SETBP1

1.40e-06168515a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIME1 IKZF2 MOGS MDC1 NR3C2

1.57e-06172515d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIME1 IKZF2 MOGS MDC1 NR3C2

1.57e-0617251510a1d1838492b8ce6dea08844353b51571432c56
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNBP1 RIPOR2 MYCBP2 IGHM SETBP1

2.02e-061815158d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENAM FNBP1 RIPOR2 MYCBP2 IGHM

2.07e-061825155f1f10c845b73d1f69794277925ef847ff23ac2d
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNBP1 RIPOR2 MYCBP2 IGHM SETBP1

2.18e-06184515942b58ae7172bb5f97e55b032db9329d161854af
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNBP1 RIPOR2 MYCBP2 IGHM SETBP1

2.18e-06184515911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 RIPOR2 RESF1 MYCBP2 IGHM

2.30e-061865151a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 RIPOR2 RESF1 MYCBP2 IGHM

2.30e-06186515f1366638edaecad5cad6367440f4c693513bed7e
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX11 LIMA1 RIPOR2 CDH2 MAP3K1

2.56e-06190515842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellB_cells-Activate_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RIPOR2 ZNF608 IGHM SETBP1 MAP3K1

2.76e-06193515b6da81920cf2e55f87ec8d4b2b5530cbf7ba2155
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron|3m / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RIPOR2 ZNF608 SHROOM2 CDH2

3.28e-06200515a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RIPOR2 ZNF608 MYCBP2 CDH2

3.28e-06200515c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PASK IKZF2 EML5 FECH

3.22e-0515851491d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCellAdult-Immune-B_cell-D231|Adult / Lineage, Cell type, age group and donor

ENAM RIPOR2 IGHM SETBP1

3.63e-051635144f5821299b265663c7d0352b28285f56e1988841
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

FNBP1 RIPOR2 IKZF2 RESF1

4.18e-05169514e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAM RIPOR2 IKZF2 IGHM

4.28e-05170514e319ab46842d028898c09d6d8f056f896edb1558
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

4.28e-051705145d5f208682be21ed58320f5fc083a7898f8712da
ToppCell3'_v3-lymph-node_spleen|World / Manually curated celltypes from each tissue

LIME1 RIPOR2 RESF1 MYCBP2

4.38e-051715147aae88da5b37c20f10118325a048f08906be994c
ToppCell343B-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ENAM RIPOR2 ZNF608 IQSEC1

4.79e-05175514b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

4.90e-05176514327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellAdult-Immune-B_cell|Adult / Lineage, Cell type, age group and donor

ENAM RIPOR2 IGHM SETBP1

4.90e-051765144aa00dcde907ad83d3aa4bb10439b7b5c4be1e5d
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

RIPOR2 IGHM SETBP1 IQSEC1

5.01e-05177514f54691e5558091c1734ab15153a10bff15ed171e
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAM RIPOR2 IKZF2 IGHM

5.01e-05177514ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRTFB IGHM SETBP1 NR3C2

5.23e-05179514a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCellChildren_(3_yrs)-Immune-B_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ENAM RIPOR2 IGHM SETBP1

5.23e-0517951431411780f1a44bf2d102f288416e97eacec4b6b6
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RIPOR2 IGHM SETBP1 IQSEC1

5.35e-0518051440a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RIPOR2 CUX1

5.44e-0564513fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.46e-051815149d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ENAM RIPOR2 IKZF2 IGHM

5.46e-0518151451e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.46e-051815146956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.58e-05182514eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.58e-051825145e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellsevere-Myeloid-Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RIPOR2 RESF1 ZNF608 PHC2

5.70e-0518351460a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.70e-05183514738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 LIME1 RIPOR2 RESF1

5.70e-05183514a492b3827d2c368d33a7a5118748beaf4d7f6797
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.70e-0518351492fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

5.82e-05184514da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

LIME1 LIMA1 IKZF2 RESF1

5.82e-0518451422c15ce30171c687ab564f4383ae74d38b759272
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 RIPOR2 RESF1 MYCBP2

5.95e-05185514e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ENAM RIPOR2 IKZF2 IGHM

5.95e-051855148fc357ee041bfd588986730a52ea2021b5f88941
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

FNBP1 RIPOR2 IGHM IQSEC1

5.95e-05185514e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

6.07e-051865145c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

RESF1 ALMS1 ZNF41 MAP3K1

6.07e-0518651403db813598b67b1e08f759758a1c2023396921fa
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ENAM RIPOR2 IGHM SETBP1

6.07e-05186514aa576748921a318798b911a611f05319b95e8d5e
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ENAM RIPOR2 IKZF2 IGHM

6.20e-051875149d298f43ae81d72091b31aaa6df41046d4aa31c5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 RESF1 IGHM IQSEC1

6.20e-05187514edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 RESF1 IGHM IQSEC1

6.20e-051875148fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCellImmune-B_cell|World / Lineage, Cell type, age group and donor

ENAM RIPOR2 IGHM IQSEC1

6.20e-05187514795690c6306c366e733279491138d0cd9b469b21
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Undetermined|metastatic_Lymph_Node / Location, Cell class and cell subclass

RIPOR2 MYCBP2 IGHM SETBP1

6.33e-051885140ddc5dbe2fd905fee20c33d9845629e259faacd9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

6.46e-051895141ecf9911ff82e0ca0f0c101b735d3b1f3b339d57
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

6.46e-05189514904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

6.46e-05189514bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN14 LRRC37A3 SETBP1 DYNC2I1

6.59e-05190514f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RIPOR2 IKZF2 IGHM IQSEC1

6.59e-05190514424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RIPOR2 MYCBP2 IGHM SETBP1

6.59e-05190514a7498fe55b7810c482291db782dc5282675d246a
ToppCell(1)_T_cells-(1)_T_CD4_fh|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PASK LIMA1 RESF1 IGHM

6.59e-05190514120ca702600373c208a3d032fede0a040736e5cf
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNBP1 PASK RIPOR2 IKZF2

6.59e-051905142a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF608 CDH2 CUX1 MAP3K1

6.73e-051915141cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPN14 CDH2 MAP3K1

6.73e-05191514d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RIPOR2 IKZF2 IGHM IQSEC1

6.73e-0519151484452125d1b5b76974e3f9126f611eff16d45c25
ToppCellB_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ENAM RIPOR2 IGHM MAP3K1

6.73e-0519151472e3191990973440e4f91427208df360f73e4f41
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ENAM FNBP1 ZNF608 MYCBP2

6.87e-0519251438ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNBP1 PASK RIPOR2 IKZF2

6.87e-0519251469a2b04f03a1b82d067018379f7b8a116e954040
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF608 LRRC37A3 SETBP1 SHROOM2

6.87e-051925146c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGHM SETBP1 IQSEC1 MAP3K1

7.01e-0519351408696a99309f5b088692ddac8cca35413b5e810d
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

RIPOR2 ZNF608 MYCBP2 CUX1

7.01e-051935142eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

FNBP1 RIPOR2 MYCBP2 SETBP1

7.01e-051935147ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 PASK RIPOR2 RESF1

7.15e-051945144138f3e8aa214504fca03962a43250670ae45215
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGHM SETBP1 IQSEC1 MAP3K1

7.15e-05194514d852aebf7a763b9a776c4570711f0c759f591910
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYCBP2 IGHM SETBP1 MAP3K1

7.15e-05194514ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 RESF1

7.15e-0519451413c3674d601c8a7355ce869de1af6401938c0037
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 PASK RIPOR2 RESF1

7.15e-05194514906fe1689906d1498acf6fd26a215c7e5a854a38
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 PASK RIPOR2 RESF1

7.15e-05194514af7428582b96a500f255c45efc02b6c10c4740d9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGHM SETBP1 IQSEC1 MAP3K1

7.29e-05195514481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGHM SETBP1 IQSEC1 MAP3K1

7.29e-051955146108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PASK LIME1 RIPOR2 RESF1

7.29e-05195514e17d05b9ef5e63b49385ddb2fbdc2ade9ea8723f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

FNBP1 SOX11 ZNF608 SETBP1

7.44e-0519651438da0751941adca650fe9b383d9f343153978eb5
ToppCellproximal-Hematologic-CD8+_Memory/Effector_T|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FNBP1 LIME1 RIPOR2 RESF1

7.44e-05196514096296e3915422b674e043deac633c6b606e415e
ToppCellproximal-Hematologic-CD8+_Memory/Effector_T-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FNBP1 LIME1 RIPOR2 RESF1

7.44e-05196514061712aea24d7e20cd813ef290b430a7042fcb79
ToppCellproximal-3-Hematologic-CD8+_Memory/Effector_T|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FNBP1 LIME1 RIPOR2 RESF1

7.44e-0519651409e5920112337b0718584b252bb331e2247ef215
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

FNBP1 SOX11 ZNF608 SETBP1

7.44e-05196514721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellSmart-seq2-lymph_node_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PASK RIPOR2 RESF1 IGHM

7.44e-051965143a8bd09a09c19df27c954d448f1bae945314c221
ToppCellSepsis-ICU-NoSEP-Lymphocyte-B-Plasmablast|ICU-NoSEP / Disease, condition lineage and cell class

ENAM EML5 C12orf50 ZNF608

7.58e-051975148f35f9741086a38f0e594dce0547b575946f52bb
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 RIPOR2 RESF1 IGHM

7.58e-051975145b172bc2f3f6bd4741600e1ea299c469685eba4f
ToppCell10x_3'_v3-blood_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RIPOR2 FECH CA1 PHC2

7.58e-051975142d3547107c88c7443fc6425742694e13368a71f5
ToppCellTransverse-T_cell-Treg|T_cell / Region, Cell class and subclass

PASK LIMA1 IKZF2 MAP3K1

7.58e-05197514b7a1637e4baadd657f6279f4aa96cd590c9cd8c9
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RIPOR2 MYCBP2 IGHM SETBP1

7.58e-0519751443e576bd6997915d21137e233e36984eba31f637
ToppCelldistal-2-Hematologic-CD4+_Naive_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PASK LIME1 RIPOR2 RESF1

7.58e-051975143339e9e03f5db6a0034d6424571b4f0b8983771b
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 IKZF2

7.73e-051985140dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCelldistal-Hematologic-CD4+_Naive_T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PASK LIME1 RIPOR2 RESF1

7.73e-051985144db9eff17778ffc3f77c017ff64f55bc1626da24
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

LIMA1 PTPN14 MRTFB ZNF608

7.73e-05198514f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RESF1 FAM120A GALNT11 DYNC2I1

7.89e-0519951461b1ed2db71b96157b92b7535d1955a4033098da
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RIPOR2 IQSEC1 CA1 PHC2

7.89e-0519951450242666def13e5d4149c563ae000d6768f086f7
ToppCell5'-GW_trimst-2-LymphNode|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 IKZF2

7.89e-051995144a9ca133125dc25a06e7b1cfea15ecffa449c20e
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 IKZF2

7.89e-0519951445d0d275ffb4183e3e71f4701e121ef9853ebd10
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 RESF1

7.89e-051995141b5b68f39102c607ae557a261c4e163b39d0c386
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PASK LIME1 RIPOR2 IKZF2

7.89e-05199514da20998253ad08a4a127a98b991b26237edb61a2
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RIPOR2 MYCBP2 CUX1

8.04e-05200514bad32a95b759fad509401b07bc96a56687c2a592
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PASK MYH7B IGHM

2.94e-0411351334ae3dec5ec7585d155ea61de6adc42aa4f45226
Diseasecancer (implicated_via_orthology)

POLE FECH RANBP6 CUX1 PHC2

9.94e-05268515DOID:162 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_marker_for)

IKZF2 IQSEC1 GRP CUX1

2.10e-04169514DOID:3908 (is_marker_for)
Diseasehormone measurement

RESF1 ATAD2B CDH2

4.20e-0484513EFO_0004730
DiseaseMalignant neoplasm of endometrium

POLE CUX1

4.40e-0418512C0007103
DiseaseCarcinoma in situ of endometrium

POLE CUX1

4.40e-0418512C0346191
Diseasehair colour measurement

PTPN14 C12orf50 MYH7B SETBP1 RANBP6 MAP3K1

6.50e-04615516EFO_0007822
Diseasediastolic blood pressure, systolic blood pressure

RIPOR2 ALMS1 SETBP1 NR3C2 CDH2 CUX1

1.01e-03670516EFO_0006335, EFO_0006336
Diseasepancreas volume

GRP PHC2

1.24e-0330512EFO_0600045

Protein segments in the cluster

PeptideGeneStartEntry
ASPQPQHQLKKPRVV

CUX1

1236

P39880
PKHNGQISDPQRDQK

ALMS1

3571

Q8TCU4
PKPLQDPEVQKHATQ

ARHGEF11

166

O15085
SRKGHETPQPQPNSK

RC3H2

396

Q9HBD1
NGHPVQQHQKEPPKQ

RC3H2

1101

Q9HBD1
KQAENGQPEPQNKVP

RC3H1

1061

Q5TC82
VQLPPSGQHIPKNLK

PASK

281

Q96RG2
PRELKQPHTQQGPEK

LRRC37A3

1211

O60309
LKGIHEEQPQQQQPP

NR3C2

681

P08235
PPHQKQPQRGEVSQK

MDC1

1821

Q14676
SQVKSEVQQPVHPKP

LIMA1

346

Q9UHB6
QAPPIVPAHQKKREN

ATAD2B

296

Q9ULI0
EVPDPNKPQKLGLHQ

IQSEC1

761

Q6DN90
KPQQHGIRPVKVNVI

DYNC2I1

901

Q8WVS4
HAGKSPNFQQPRPDK

MYH7B

601

A7E2Y1
HAKPQQPIFVNRGPK

GALNT11

461

Q8NCW6
KENRNHQPPQPKALG

GRP

91

P07492
GPALVKQSHPKNPND

MRTFB

261

Q9ULH7
VGIPHQLSKPQRQKQ

LRRC37B

206

Q96QE4
LQQVKNPVPRVKHPD

POLE

1151

Q07864
QIVSHVQNKGTPPPK

FAM120A

121

Q9NZB2
QGHPALNPKRKQSPA

IKZF2

421

Q9UKS7
GNHTKAVQLKPRPPQ

MOGS

656

Q13724
QHPNGNKEKNVPLPV

IGHM

91

P01871
TGHPVQENQPKRKPS

DKK4

116

Q9UBT3
GPQSPKQQKEPLSHR

FNBP1

356

Q96RU3
PMQHNNRPTQPLKGR

CA1

241

P00915
RHPAQALGKPKNQQE

KIAA1210

876

Q9ULL0
KRPLKQPSHNQPQPE

ENAM

136

Q9NRM1
APPQPEKLQTNNVGK

EML5

1341

Q05BV3
EEKGPQQRKHGQQPL

DCST2

706

Q5T1A1
QHAQGAKPQVQPQKR

FECH

51

P22830
NQVPLAKGIQHPPQS

CDH2

466

P19022
QPKPMVQTKGRPHSQ

MAP3K1

951

Q13233
KNITKQHPPPLAQPA

SOX11

316

P35716
KPHPRKEQAPLQVSG

RESF1

1656

Q9HCM1
QRNPKNNVVPSKPGA

PTPN14

516

Q15678
KPVPQRPAQKQALHG

SHROOM2

806

Q13796
QQDQAKKPQRIPGSP

MYCBP2

2321

O75592
NHPVVIGPNNSNLPK

RANBP6

1031

O60518
HNLGHKNNNPPKEPQ

RIPOR2

56

Q9Y4F9
NKVHANREPKPNLSP

C12orf50

361

Q8NA57
APQNGENKPPQAIVK

PHC2

551

Q8IXK0
TQRQNVVKPIDNPPH

RPAP3

411

Q9H6T3
GNSPKKQASRPPIQN

RRP36

71

Q96EU6
QPSKDVHVVKEQNPP

TP53BP1

241

Q12888
LSQPRPGHANLKPNQ

SKOR2

26

Q2VWA4
SNKVFPQKPQVDVHP

ZNF41

346

P51814
EPNKNHSKLGPSVPN

ZNF608

1161

Q9ULD9
HKPSQHNPKLNKNPG

USP30

361

Q70CQ3
GKRKHKPQAPAQPPQ

SETBP1

1551

Q9Y6X0
QKRKGTHRSPQEPQQ

LIME1

171

Q9H400