Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC52A1 SLC16A9 NALCN SLC19A1 SLC2A6 SLCO2A1 SLC5A9 LRP5 GRIA2 SLC36A3 GRIA4 SLC12A8 SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC22A24 SLC12A7 MFSD4B SLC16A7 TMEM87A ABCA9 SLC22A17 SVOPL ABCG8 SLC2A4 RHD

2.61e-2411808137GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC52A1 SLC16A9 NALCN SLC19A1 SLC2A6 SLCO2A1 SLC5A9 LRP5 GRIA2 SLC36A3 GRIA4 SLC12A8 ATP9B SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC22A24 SLC12A7 MFSD4B SLC16A7 TMEM87A ABCA9 SLC22A17 SVOPL ABCG8 SLC2A4 RHD

4.34e-2412898138GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A4 SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC16A9 SLC19A1 SLCO2A1 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC12A7 MFSD4B SLC16A7 SLC2A4

1.40e-162968118GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A4 SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC16A9 SLC19A1 SLCO2A1 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC12A7 MFSD4B SLC16A7 ABCA9 ABCG8 SLC2A4

3.02e-154778120GO:0022804
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC36A3 GRIA4 SLC12A8 SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC12A7 TMEM87A SLC2A4 RHD

3.91e-156278122GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC22A6 SLC9A3 NALCN SLC5A9 GRIA2 SLC36A3 GRIA4 SLC12A8 SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC12A7 TMEM87A SLC2A4 RHD

1.81e-147588123GO:0015318
GeneOntologyMolecularFunctionsymporter activity

SLC6A4 SLC6A7 SLC6A12 SLC16A9 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC12A7 MFSD4B SLC16A7 SLC2A4

3.46e-141508113GO:0015293
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC19A1 SLC5A9 GRIA2 SLC36A3 GRIA4 SLC12A8 SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC12A7 TMEM87A SLC2A4

4.57e-137938122GO:0015075
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC52A1 SLC16A9 SLC19A1 SLC2A6 SLCO2A1 GRIA2 SLC36A3 GRIA4 SLC10A3 SLC46A1 SLC16A7

7.52e-132938115GO:0008514
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC36A3 SLC12A8 SLC10A3 CATSPER3 SLC46A1 NIPAL3 SLC12A7 TMEM87A SLC2A4

1.45e-126648120GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A4 CACNA1A SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC12A8 SLC10A3 CATSPER3 NIPAL3 SLC12A7 TMEM87A

4.85e-114658116GO:0046873
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A4 SLC6A7 SLC6A12 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC12A7 SLC2A4

5.07e-111198110GO:0015294
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A7 SLC6A12 SLC22A6 SLC16A9 SLC19A1 GRIA2 SLC36A3 GRIA4 SLC10A3 SLC46A1 SLC16A7

7.32e-102078111GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A7 SLC6A12 SLC22A6 SLC16A9 SLC19A1 GRIA2 SLC36A3 GRIA4 SLC10A3 SLC46A1 SLC16A7

7.71e-102088111GO:0005342
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR5G3 OR2T35 INSRR OR4D1 RRH OR2T1 LRP5 GRIA2 GRIA4 OR8B12 GPRC6A OR8J1 OR7A17 GABBR2 SLC22A17 OR52A1 S1PR4 OR8B8

2.27e-0913538123GO:0004888
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A4 SLC6A7 SLC6A12 SLC9A3 SLC19A1 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC12A7 SLC2A4

3.09e-093018112GO:0022853
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR5G3 OR2T35 OR4D1 RRH OR2T1 OR8B12 GPRC6A OR8J1 OR7A17 GABBR2 OR52A1 S1PR4 OR8B8

1.18e-088848118GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.83e-084318113GO:0004984
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A4 SLC6A7 SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC10A3

4.64e-07171818GO:0015081
GeneOntologyMolecularFunctionchannel activity

SLC6A4 CACNA1A ATP5MC3 CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3 SLC12A7 TMEM87A RHD

1.31e-065258112GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC6A4 CACNA1A ATP5MC3 CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3 SLC12A7 TMEM87A RHD

1.34e-065268112GO:0022803
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A4 SLC6A12 SLC12A8 SLC12A7

2.10e-0623814GO:0015377
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A6 SLC5A9 MFSD4B SLC2A4

2.98e-0625814GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A6 SLC5A9 MFSD4B SLC2A4

2.98e-0625814GO:0015149
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A4 SLC6A12 SLC12A8 SLC12A7

3.51e-0626814GO:0015296
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A6 SLC5A9 MFSD4B SLC2A4

4.11e-0627814GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A6 SLC5A9 MFSD4B SLC2A4

5.52e-0629814GO:0051119
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC52A1 SLC19A1 SLC2A6 SLC46A1

1.34e-0536814GO:0090482
GeneOntologyMolecularFunctionmethotrexate transmembrane transporter activity

SLC19A1 SLC46A1

1.63e-052812GO:0015350
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A4 SLC6A7 SLC6A12 SLC5A9 SLC10A3

1.95e-0581815GO:0015370
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1E CACNA1S

2.27e-0514813GO:0008331
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A6 SLC5A9 MFSD4B SLC2A4

2.50e-0542814GO:0015144
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1E CACNA1S CATSPER3

3.60e-0546814GO:0005245
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A12 SLC10A3 SLC16A7

5.95e-0519813GO:0015355
GeneOntologyMolecularFunctiongated channel activity

CACNA1A ATP5MC3 CACNA1E CACNA1S GRIA2 GRIA4 CATSPER3 TMEM87A

6.27e-05334818GO:0022836
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A7 SLC6A12 GRIA2 SLC36A3 GRIA4

6.82e-05105815GO:0015171
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC6A4 CACNA1A CACNA1E CACNA1S NALCN GRIA2 CATSPER3 TMEM87A

7.55e-05343818GO:0005261
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA2 GRIA4

9.70e-054812GO:0004971
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC6A4 CACNA1A CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3 TMEM87A

9.99e-05459819GO:0005216
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC36A3 SLC46A1 SLC2A4

1.39e-0425813GO:0015295
GeneOntologyMolecularFunctionlipid transporter activity

SLC22A6 SLCO2A1 ATP9B SLC10A3 ABCA9 ABCG8

1.46e-04196816GO:0005319
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A7 SLC6A12 SLC36A3

2.18e-0429813GO:0005416
GeneOntologyMolecularFunctionfolic acid transmembrane transporter activity

SLC19A1 SLC46A1

2.41e-046812GO:0008517
GeneOntologyMolecularFunctionantiporter activity

SLC6A4 SLC22A6 SLC35A3 SLC9A3 SLC19A1

2.46e-04138815GO:0015297
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC22A6 SLC19A1 SLC46A1

2.66e-0431813GO:0005310
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC16A9 SLC19A1 SLC46A1

3.21e-0433813GO:0072349
GeneOntologyMolecularFunctionL-proline transmembrane transporter activity

SLC6A7 SLC36A3

3.37e-047812GO:0015193
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC22A6 SLC19A1 SLC46A1

3.51e-0434813GO:0042910
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A4 SLC6A12 SLC19A1 SLC12A8 SLC12A7

3.73e-04151815GO:0008509
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A7 SLC6A12 SLC10A3

3.83e-0435813GO:0005343
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC6A12 SLC16A9 SLC10A3 SLC16A7

4.93e-0490814GO:0008028
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A8 SLC12A7

5.74e-049812GO:0015379
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1E

5.74e-049812GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1E

5.74e-049812GO:0099626
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A3 GRIA2 SLC12A8 SLC12A7 TMEM87A

5.91e-04167815GO:0015079
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A4 SLC6A12 SLC22A6 SLC12A8 SLC12A7

6.58e-04171815GO:0015103
GeneOntologyMolecularFunctionamyloid-beta binding

CACNA1A GRIA2 GRIA4 ITM2B

7.90e-04102814GO:0001540
GeneOntologyMolecularFunctionproton transmembrane transporter activity

ATP5MC3 SLC9A3 SLC36A3 SLC46A1 SLC2A4

1.01e-03188815GO:0015078
GeneOntologyMolecularFunctionammonium channel activity

SLC12A7 RHD

1.04e-0312812GO:0008519
GeneOntologyMolecularFunctionamide binding

CACNA1A SLC19A1 GRIA2 GRIA4 SLC46A1 ITM2B

1.36e-03299816GO:0033218
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLC22A6 SLCO2A1

1.43e-0314812GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLC22A6 SLCO2A1

1.65e-0315812GO:0071714
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A12 SLC10A3

1.65e-0315812GO:0140161
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A4 SLC6A12 SLC12A8 SLC12A7

1.68e-03125814GO:0015108
GeneOntologyMolecularFunctionodorant binding

OR5G3 OR8B12 OR8J1 OR8B8

1.78e-03127814GO:0005549
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1E CACNA1S CATSPER3

1.88e-03129814GO:0005262
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A9 SLC2A4

2.12e-0317812GO:0005402
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A4 SLC6A12

2.12e-0317812GO:0015378
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA2 GRIA4

2.12e-0317812GO:0004970
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A6 SLCO2A1

2.38e-0318812GO:0015347
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A4 SLC6A12

2.66e-0319812GO:0015373
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC6A4 SLC10A3 SLC16A7

2.89e-0370813GO:1901618
GeneOntologyMolecularFunctionfolic acid binding

SLC19A1 SLC46A1

2.94e-0320812GO:0005542
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLC22A6 SLCO2A1 SLC10A3

3.26e-0373813GO:0170055
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1E CACNA1S CATSPER3

3.33e-03151814GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A CACNA1E CACNA1S CATSPER3

3.41e-03152814GO:0022843
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A7 SLC6A12

3.89e-0323812GO:0005283
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA2 GRIA4

4.23e-0324812GO:0099507
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC6A7 SLC16A9 SLC36A3

4.68e-0383813GO:0015101
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA2 GRIA4

5.34e-0327812GO:0008066
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A CACNA1E CACNA1S CATSPER3

6.44e-03182814GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A CACNA1E CACNA1S CATSPER3

6.69e-03184814GO:0022832
GeneOntologyMolecularFunctionpeptide binding

CACNA1A NPY5R GRIA2 GRIA4 ITM2B

9.49e-03318815GO:0042277
GeneOntologyBiologicalProcessorganic anion transport

CACNA1A SLC6A7 SLC6A12 SLC22A6 SLC35A3 NPY5R SLC52A1 SLC16A9 SLC19A1 SLC2A6 SLCO2A1 SLC36A3 SLC10A3 SLC46A1 SLC22A24 SLC16A7 SLC2A4

1.04e-115158017GO:0015711
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC22A6 SLC9A3 NALCN SLC19A1 SLC5A9 GRIA2 SLC36A3 GRIA4 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC22A24 SLC12A7 MFSD4B SLC22A17

2.07e-1013748024GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC19A1 SLC5A9 GRIA2 SLC36A3 GRIA4 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7

6.10e-0911158020GO:0034220
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.10e-084328013GO:0050911
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 SLC36A3 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7 RHD

1.11e-089228018GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC36A3 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7 MFSD4B SLC22A17

1.14e-0811578020GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 GRIA2 SLC36A3 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7

1.55e-089428018GO:0098655
GeneOntologyBiologicalProcesssensory perception of smell

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

2.62e-084658013GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

4.30e-084858013GO:0050907
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 TMEM87A OR52A1 OR8B8

4.72e-085828014GO:0050906
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A4 CACNA1A ATP5MC3 SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 SLC36A3 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7 RHD

4.99e-0810178018GO:0098660
GeneOntologyBiologicalProcesscarboxylic acid transport

CACNA1A SLC6A7 SLC6A12 SLC22A6 NPY5R SLC16A9 SLC19A1 SLCO2A1 SLC36A3 SLC10A3 SLC46A1 SLC16A7

5.77e-084108012GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

CACNA1A SLC6A7 SLC6A12 SLC22A6 NPY5R SLC16A9 SLC19A1 SLCO2A1 SLC36A3 SLC10A3 SLC46A1 SLC16A7

6.09e-084128012GO:0015849
GeneOntologyBiologicalProcessdetection of stimulus

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 TMEM87A OR52A1 OR8B8

1.01e-077228015GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.05e-075248013GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.73e-075478013GO:0007606
GeneOntologyBiologicalProcessmetal ion transport

SLC6A4 CACNA1A SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 NALCN SLC5A9 SLC12A8 CATSPER3 SLC46A1 NIPAL3 BPIFA1 SLC12A7 MFSD4B SLC22A17

2.23e-0710008017GO:0030001
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A SLC6A7 CACNA1E CACNA1S SLC9A3 SLC19A1 SLC12A8 SLC46A1 SLC12A7

2.66e-07230809GO:0098739
GeneOntologyBiologicalProcesssodium ion transport

SLC6A4 SLC6A7 SLC6A12 SLC9A3 NALCN SLC5A9 CATSPER3 BPIFA1 MFSD4B

1.19e-06275809GO:0006814
GeneOntologyBiologicalProcessvitamin transport

SLC52A1 SLC19A1 SLC2A6 SLC46A1 SLC2A4

2.53e-0656805GO:0051180
GeneOntologyBiologicalProcesssensory perception

OR10A3 CACNA1E OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 TMEM87A OR52A1 OR8B8

2.95e-0610728016GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR5G3 OR2T35 OR4D1 RRH OR2T1 OR8B12 GPRC6A OR8J1 OR7A17 GABBR2 OR52A1 S1PR4 OR8B8

4.98e-0613958018GO:0007186
GeneOntologyBiologicalProcessamino acid transport

SLC6A4 CACNA1A SLC6A7 SLC6A12 NPY5R LRP5 SLC36A3

1.07e-05195807GO:0006865
GeneOntologyBiologicalProcessimport into cell

SLC6A4 CACNA1A SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 SLC19A1 LRP5 GRIA2 SLC12A8 ATP9B SLC46A1 SLC12A7 SLC2A4

1.40e-0510748015GO:0098657
GeneOntologyBiologicalProcessmethotrexate transport

SLC19A1 SLC46A1

1.49e-052802GO:0051958
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A4 SLC6A7 SLC6A12 SLC9A3 NALCN SLC5A9 BPIFA1

1.63e-05208807GO:0035725
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A CACNA1E CACNA1S SLC9A3 SLC12A8 SLC12A7

1.89e-05142806GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A CACNA1E CACNA1S SLC9A3 SLC12A8 SLC12A7

1.89e-05142806GO:0098659
GeneOntologyBiologicalProcessmodified amino acid transport

SLC6A12 SLC16A9 SLC19A1 SLC46A1

2.53e-0544804GO:0072337
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC6A7 SLC16A9 SLC19A1 SLC36A3 SLC46A1 SLC16A7

4.12e-05163806GO:1905039
GeneOntologyBiologicalProcessfolate import across plasma membrane

SLC19A1 SLC46A1

4.45e-053802GO:1904447
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC6A7 SLC16A9 SLC19A1 SLC36A3 SLC46A1 SLC16A7

4.72e-05167806GO:1903825
GeneOntologyBiologicalProcesschloride ion homeostasis

CACNA1A SLC12A8 SLC12A7

1.22e-0425803GO:0055064
GeneOntologyBiologicalProcessfolate transmembrane transport

SLC19A1 SLC46A1

1.47e-045802GO:0098838
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

CACNA1A SLC12A8 SLC12A7

1.72e-0428803GO:0055081
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC6A12 SLC22A6 SLC16A9 SLCO2A1 SLC10A3 SLC16A7

1.80e-04213806GO:0015718
GeneOntologyBiologicalProcesssynaptic transmission, GABAergic

CACNA1A NPY5R NALCN GABBR2

1.96e-0474804GO:0051932
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1A CACNA1E CACNA1S SLC6A12 SLC9A3 LRP5 SLC12A8 SLC46A1 BPIFA1 SLC12A7 SLC22A17 ABCG8 SLC2A4 RHD

2.91e-0412498014GO:0048878
GeneOntologyBiologicalProcessdehydroascorbic acid transport

SLC2A6 SLC2A4

5.25e-049802GO:0070837
GeneOntologyBiologicalProcesscell volume homeostasis

SLC6A12 SLC12A8 SLC12A7

5.78e-0442803GO:0006884
GeneOntologyBiologicalProcesscarbohydrate transport

SLC35A3 SLC2A6 SLC5A9 MFSD4B SLC2A4

7.86e-04186805GO:0008643
GeneOntologyBiologicalProcessproline transmembrane transport

SLC6A7 SLC36A3

7.99e-0411802GO:0035524
GeneOntologyBiologicalProcessfolic acid transport

SLC19A1 SLC46A1

7.99e-0411802GO:0015884
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1E CACNA1S

8.57e-0448803GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1E CACNA1S

8.57e-0448803GO:1902656
GeneOntologyBiologicalProcessiron coordination entity transport

SLC46A1 SLC22A17

9.56e-0412802GO:1901678
GeneOntologyBiologicalProcessammonium transmembrane transport

SLC12A7 RHD

1.13e-0313802GO:0072488
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC22A6 NPY5R SLC19A1 SLC46A1

1.23e-03120804GO:0006835
GeneOntologyBiologicalProcessamino-acid betaine transport

SLC6A12 SLC16A9

1.31e-0314802GO:0015838
GeneOntologyBiologicalProcesssodium-independent organic anion transport

SLC22A6 SLCO2A1

1.51e-0315802GO:0043252
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1E CACNA1S CATSPER3

3.02e-0546814GO:0005891
GeneOntologyCellularComponentpresynaptic membrane

SLC6A4 CACNA1A SLC6A7 CACNA1E GRIA2 GRIA4 GABBR2

1.00e-04277817GO:0042734
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A ATP5MC3 CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3

1.08e-04378818GO:0034702
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CACNA1E CACNA1S CATSPER3

1.86e-0473814GO:0034704
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A ATP5MC3 CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3 ABCG8

1.89e-04523819GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1A ATP5MC3 CACNA1E CACNA1S NALCN GRIA2 GRIA4 CATSPER3 ABCG8

2.74e-04550819GO:1990351
GeneOntologyCellularComponentcation channel complex

CACNA1A ATP5MC3 CACNA1E CACNA1S GRIA4 CATSPER3

3.04e-04235816GO:0034703
GeneOntologyCellularComponentpresynapse

SLC6A4 CACNA1A SLC6A7 CACNA1E SLC6A12 NPY5R GRIA2 GRIA4 GABBR2 SLC2A4 S1PR4

6.00e-048868111GO:0098793
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A CACNA1E CACNA1S INSRR LRP5 GRIA2 GRIA4 CATSPER3 GABBR2 ABCG8

8.90e-047858110GO:0098797
GeneOntologyCellularComponentpostsynaptic membrane

SLC6A4 CACNA1A CACNA1E GRIA2 GRIA4 GABBR2 SLC16A7

9.87e-04405817GO:0045211
GeneOntologyCellularComponentbasolateral plasma membrane

SLC6A12 SLC22A6 SLC19A1 SLCO2A1 SLC46A1 SLC16A7

1.52e-03320816GO:0016323
GeneOntologyCellularComponentdendritic spine head

CACNA1S GRIA2

1.72e-0316812GO:0044327
GeneOntologyCellularComponentmembrane protein complex

CACNA1A ATP5MC3 CACNA1E OSTC CACNA1S NALCN INSRR LRP5 GRIA2 GRIA4 CATSPER3 GABBR2 ABCG8 RHD

1.73e-0314988114GO:0098796
GeneOntologyCellularComponentsynaptic membrane

SLC6A4 CACNA1A SLC6A7 CACNA1E GRIA2 GRIA4 GABBR2 SLC16A7

1.88e-03583818GO:0097060
GeneOntologyCellularComponentbasal plasma membrane

SLC6A12 SLC22A6 SLC19A1 SLCO2A1 SLC46A1 SLC16A7

2.53e-03354816GO:0009925
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA1A GRIA2 GRIA4

3.46e-0378813GO:0048787
GeneOntologyCellularComponentbasal part of cell

SLC6A12 SLC22A6 SLC19A1 SLCO2A1 SLC46A1 SLC16A7

3.49e-03378816GO:0045178
GeneOntologyCellularComponentbrush border membrane

SLC9A3 SLC19A1 SLC46A1

4.12e-0383813GO:0031526
HumanPhenoFolate-responsive megaloblastic anemia

SLC19A1 SLC46A1

2.51e-052262HP:0004851
MousePhenoabnormal nervous system electrophysiology

SLC6A4 CACNA1A NALCN GDAP1 GRIA2 GRIA4 GABBR2 TMEM87A

2.64e-05329528MP:0002272
DomainMFS_dom

SLC22A6 SLC16A9 SLC19A1 SLC2A6 SLCO2A1 SLC46A1 SLC22A24 MFSD4B SLC16A7 SLC22A17 SVOPL SLC2A4

4.49e-131348012IPR020846
DomainMFS

SLC22A6 SLC16A9 SLC2A6 SLCO2A1 SLC46A1 SLC22A24 SLC16A7 SLC22A17 SVOPL SLC2A4

3.21e-111088010PS50850
DomainMFS

SLC16A9 SLC46A1 SLC22A24 MFSD4B SLC16A7 SLC22A17 SVOPL

3.83e-0877807IPR011701
DomainMFS_1

SLC16A9 SLC46A1 SLC22A24 MFSD4B SLC16A7 SLC22A17 SVOPL

3.83e-0877807PF07690
DomainOlfact_rcpt

OR10A3 OR51B5 OR2AK2 OR2T27 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.06e-073938012IPR000725
DomainGPCR_Rhodpsn_7TM

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 S1PR4 OR8B8

1.37e-076708015IPR017452
Domain7tm_1

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 S1PR4 OR8B8

1.56e-076778015PF00001
DomainG_PROTEIN_RECEP_F1_1

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 S1PR4 OR8B8

1.82e-076858015PS00237
DomainG_PROTEIN_RECEP_F1_2

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 S1PR4 OR8B8

2.03e-076918015PS50262
DomainGPCR_Rhodpsn

OR10A3 OR51B5 OR2AK2 NPY5R OR2T27 OR2T35 OR4D1 RRH OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 S1PR4 OR8B8

2.07e-076928015IPR000276
DomainSugar_tr

SLC22A6 SLC2A6 SLC22A17 SVOPL SLC2A4

4.32e-0736805PF00083
DomainMFS_sugar_transport-like

SLC22A6 SLC2A6 SLC22A17 SVOPL SLC2A4

4.32e-0736805IPR005828
DomainGPHH_dom

CACNA1A CACNA1E CACNA1S

2.62e-067803IPR031649
DomainVDCC_a1su_IQ

CACNA1A CACNA1E CACNA1S

2.62e-067803IPR014873
DomainCa_chan_IQ

CACNA1A CACNA1E CACNA1S

2.62e-067803SM01062
DomainCa_chan_IQ

CACNA1A CACNA1E CACNA1S

2.62e-067803PF08763
DomainGPHH

CACNA1A CACNA1E CACNA1S

2.62e-067803PF16905
DomainVDCCAlpha1

CACNA1A CACNA1E CACNA1S

8.89e-0610803IPR002077
DomainSugar_transporter_CS

SLC2A6 SLC46A1 SLC22A17 SLC2A4

1.02e-0532804IPR005829
DomainANF_receptor

GRIA2 GRIA4 GPRC6A GABBR2

1.85e-0537804PF01094
DomainANF_lig-bd_rcpt

GRIA2 GRIA4 GPRC6A GABBR2

1.85e-0537804IPR001828
DomainPeripla_BP_I

GRIA2 GRIA4 GPRC6A GABBR2

2.29e-0539804IPR028082
DomainNA_NEUROTRAN_SYMP_2

SLC6A4 SLC6A7 SLC6A12

5.90e-0518803PS00754
DomainNA_NEUROTRAN_SYMP_3

SLC6A4 SLC6A7 SLC6A12

6.98e-0519803PS50267
DomainSNF

SLC6A4 SLC6A7 SLC6A12

6.98e-0519803PF00209
DomainNa/ntran_symport

SLC6A4 SLC6A7 SLC6A12

6.98e-0519803IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A4 SLC6A7 SLC6A12

6.98e-0519803PS00610
DomainChannel_four-helix_dom

CACNA1A CACNA1E CACNA1S NALCN

1.04e-0457804IPR027359
Domain-

CACNA1A CACNA1E CACNA1S NALCN

1.04e-04578041.20.120.350
DomainLung_7-TM_R

TMEM87B TMEM87A

1.08e-044802PF06814
DomainGPR107-like

TMEM87B TMEM87A

1.08e-044802IPR009637
DomainIon_trans_dom

CACNA1A CACNA1E CACNA1S NALCN CATSPER3

1.30e-04114805IPR005821
DomainIon_trans

CACNA1A CACNA1E CACNA1S NALCN CATSPER3

1.30e-04114805PF00520
DomainSUGAR_TRANSPORT_1

SLC2A6 SLC22A17 SLC2A4

1.44e-0424803PS00216
DomainGPCR_3_CS

GPRC6A GABBR2

1.59e-0314802IPR017979
DomainSugar/inositol_transpt

SLC2A6 SLC2A4

1.59e-0314802IPR003663
DomainSUGAR_TRANSPORT_2

SLC2A6 SLC2A4

2.36e-0317802PS00217
DomainIontro_rcpt

GRIA2 GRIA4

2.65e-0318802IPR001320
DomainLig_chan

GRIA2 GRIA4

2.65e-0318802PF00060
DomainLig_chan-Glu_bd

GRIA2 GRIA4

2.65e-0318802PF10613
DomainPBPe

GRIA2 GRIA4

2.65e-0318802SM00079
DomainIono_rcpt_met

GRIA2 GRIA4

2.65e-0318802IPR001508
DomainGlu/Gly-bd

GRIA2 GRIA4

2.65e-0318802IPR019594
DomainLig_chan-Glu_bd

GRIA2 GRIA4

2.65e-0318802SM00918
DomainGPCR_3

GPRC6A GABBR2

3.61e-0321802IPR000337
DomainAA-permease/SLC12A_dom

SLC12A8 SLC12A7

3.96e-0322802IPR004841
DomainG_PROTEIN_RECEP_F3_4

GPRC6A GABBR2

3.96e-0322802PS50259
Domain7tm_3

GPRC6A GABBR2

3.96e-0322802PF00003
DomainGPCR_3_C

GPRC6A GABBR2

3.96e-0322802IPR017978
DomainG_PROTEIN_RECEP_F3_2

GPRC6A GABBR2

3.96e-0322802PS00980
DomainG_PROTEIN_RECEP_F3_3

GPRC6A GABBR2

3.96e-0322802PS00981
DomainAA_permease

SLC12A8 SLC12A7

3.96e-0322802PF00324
DomainG_PROTEIN_RECEP_F3_1

GPRC6A GABBR2

3.96e-0322802PS00979
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 NALCN SLC2A6 SLCO2A1 SLC5A9 PSMD2 ATP9B SLC46A1 NIPAL3 SLC12A7 MFSD4B SLC16A7 ABCA9 SLC22A17 ABCG8 SLC2A4

5.38e-117366520M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 NALCN SLC2A6 SLCO2A1 SLC5A9 PSMD2 ATP9B SLC46A1 NIPAL3 SLC12A7 SLC16A7 ABCA9 SLC22A17 ABCG8 SLC2A4

1.18e-106816519MM14985
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC2A6 SLCO2A1 SLC5A9 SLC12A7 MFSD4B SLC16A7 SLC2A4

1.24e-092496512M5988
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC2A6 SLCO2A1 SLC5A9 SLC12A7 SLC16A7 SLC2A4

1.01e-082386511MM15076
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

4.47e-084176513M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR10A3 OR51B5 OR2AK2 OR2T27 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

1.44e-063896511M14091
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A6 SLC5A9 MFSD4B SLC2A4

2.32e-0621654M27058
PathwayREACTOME_SENSORY_PERCEPTION

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

5.34e-066366513M41834
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1E CACNA1S

1.50e-0511653M47958
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

SLC6A4 CACNA1A CACNA1E SLC6A12 GRIA2 GRIA4 GABBR2

5.08e-05211657MM14502
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A6 SLC5A9 SLC2A4

8.60e-0519653MM14718
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

CACNA1A GRIA2 GRIA4

1.35e-0422653M39795
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1E CACNA1S

1.55e-0423653M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1E CACNA1S

2.00e-0425653M47948
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

SLC6A4 CACNA1A CACNA1E SLC6A12 GRIA2 GRIA4 GABBR2

2.36e-04270657M15514
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

CACNA1A GRIA4 GABBR2 SLC16A7

3.53e-0473654MM16641
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A7 SLC6A12 SLC22A6 SLC16A7

4.12e-0476654MM15072
PathwayWP_NRF2_PATHWAY

SLC6A4 SLC6A7 SLC2A6 SLC5A9 SLC2A4

4.76e-04141655M39454
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A7 SLC6A12 SLC22A6 SLC16A7

6.02e-0484654M27334
PathwayREACTOME_NEURONAL_SYSTEM

SLC6A4 CACNA1A CACNA1E SLC6A12 GRIA2 GRIA4 GABBR2

8.58e-04335657MM14503
PathwayREACTOME_CREATINE_METABOLISM

SLC6A7 SLC6A12

1.12e-0311652M27681
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.12e-0311652MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.12e-0311652M26913
PathwayREACTOME_CREATINE_METABOLISM

SLC6A7 SLC6A12

1.12e-0311652MM15402
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1E SLC2A4

1.31e-0347653M19708
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

NPY5R RRH OR8B12 OR7A17 OR8B8

1.65e-03186655MM15994
Pubmed

The human olfactory receptor gene family.

OR10A3 OR51B5 OR2AK2 OR2T27 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR52A1 OR8B8

3.87e-10541811314983052
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

SLC6A7 CACNA1E CACNA1S SLC6A12 SLC9A3 SLC19A1 SLCO2A1 GABBR2

1.67e-0914381820424473
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR10A3 OR2AK2 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR8B8

7.10e-09340811011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR10A3 OR2AK2 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR8B8

7.10e-09340811011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR10A3 OR2AK2 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR8B8

7.72e-09343811032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR10A3 OR2AK2 OR5G3 OR2T35 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR8B8

8.38e-09346811014611657
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR4D1 OR2T1 OR7A17 OR8B8

2.80e-07248149119360
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR10A3 OR4D1 OR2T1 OR8B12 OR8J1 OR7A17 OR8B8

8.35e-0721981712213199
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1E CACNA1S

1.01e-06981316382099
Pubmed

Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.

SLC19A1 SLC46A1

5.36e-06281220053979
Pubmed

Deregulation of the A-to-I RNA editing mechanism in psychiatric disorders.

GRIA2 GRIA4

5.36e-06281221984433
Pubmed

Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy.

SLC19A1 SLC46A1

5.36e-06281226193446
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

5.36e-06281216381801
Pubmed

Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine.

SLC19A1 SLC46A1

5.36e-06281218650265
Pubmed

Hypokalaemic periodic paralysis due to the CACNA1S R1239H mutation in a large African family.

CACNA1A CACNA1S

5.36e-06281217418573
Pubmed

Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder.

GRIA2 GRIA4

5.36e-06281223613500
Pubmed

Genetic analysis of GRIA2 and GRIA4 genes in migraine.

GRIA2 GRIA4

5.36e-06281224512576
Pubmed

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.

TMEM87B TMEM87A

5.36e-06281226157166
Pubmed

The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.

SLC19A1 SLC46A1

5.36e-06281224396145
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1E CACNA1S

5.43e-061581320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1E CACNA1S

5.43e-061581324453333
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A4 SLC6A7 SLC6A12

1.57e-052181316125675
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia.

GRIA2 GRIA4

1.60e-05381222094384
Pubmed

Superactivation of AMPA receptors by auxiliary proteins.

GRIA2 GRIA4

1.60e-05381226744192
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder.

GRIA2 GRIA4

1.60e-05381222057216
Pubmed

Linking supply to demand: the neuronal monocarboxylate transporter MCT2 and the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid receptor GluR2/3 subunit are associated in a common trafficking process.

GRIA2 SLC16A7

1.60e-05381219453627
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA2 GRIA4

1.60e-05381218163426
Pubmed

Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities.

GRIA2 GRIA4

1.60e-05381230692144
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1E

1.60e-05381238996073
Pubmed

Decreased placental folate transporter expression and activity in first and second trimester in obese mothers.

SLC19A1 SLC46A1

1.60e-05381231926453
Pubmed

Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells.

GRIA2 GRIA4

1.60e-05381229352045
Pubmed

Expression of folate transporters in human placenta and implications for homocysteine metabolism.

SLC19A1 SLC46A1

1.60e-05381220036773
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1E

1.60e-05381224523520
Pubmed

Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder.

GRIA2 GRIA4

1.60e-05381222122651
Pubmed

SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients.

SLC19A1 SLC46A1

1.60e-05381225124723
Pubmed

Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.

SLC19A1 SLC46A1

1.60e-05381233737637
Pubmed

DNA methylation and expression of the folate transporter genes in colorectal cancer.

SLC19A1 SLC46A1

1.60e-05381225697897
Pubmed

Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.

GRIA2 GRIA4 SLC10A3

2.08e-05238138464923
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR2AK2 OR2T35 OR8J1 OR7A17

2.77e-057481415081110
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1E

3.20e-05481232616470
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA2 GRIA4

3.20e-05481210688364
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA2 GRIA4

3.20e-05481228608780
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA2 GRIA4

3.20e-0548129221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA2 GRIA4

3.20e-05481225337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA2 GRIA4

3.20e-05481217828255
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA2 GRIA4

3.20e-05481224652293
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA2 GRIA4

3.20e-05481217409242
Pubmed

LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory.

GRIA2 GRIA4

3.20e-05481229915039
Pubmed

Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy.

GRIA2 GABBR2

3.20e-05481216724110
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA2 GRIA4

3.20e-05481214561864
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA2 GRIA4

3.20e-05481210027300
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1E

3.20e-05481237141091
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA2 GRIA4

3.20e-0548121319477
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA2 GRIA4

3.20e-05481212692557
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA2 GRIA4

3.20e-05481212125045
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA2 GRIA4

3.20e-0548129648857
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1E

5.33e-0558128825650
Pubmed

RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.

GRIA2 GRIA4

5.33e-05581236179027
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA2 GRIA4

5.33e-0558121717158
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA2 GRIA4

5.33e-05581216129400
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1E

5.33e-05581215451373
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA2 GRIA4

5.33e-0558129482932
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1E

5.33e-05581211296258
Pubmed

Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.

GRIA2 GRIA4

5.33e-05581215797551
Pubmed

Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.

TMEM87B TMEM87A

5.33e-05581236373655
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

ELMOD2 LEMD3 SLC19A1 TMEM87B PSMD2 SSR1 NCLN SLC12A7 MFSD4B TMEM87A

7.30e-05952811038569033
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

SLC6A4 SLC6A12 NPY5R GRIA2 GRIA4 GABBR2

7.39e-0530081619086053
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1E

7.99e-05681235324301
Pubmed

Mouse hippocampal GABAB1 but not GABAB2 subunit-containing receptor complex levels are paralleling retrieval in the multiple-T-maze.

GRIA2 GABBR2

7.99e-05681226539091
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1E

7.99e-05681212827191
Pubmed

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits.

GRIA2 GRIA4

7.99e-05681218922769
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1E

7.99e-0568129238069
Pubmed

Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos.

SLC19A1 SLC46A1

7.99e-05681223904512
Pubmed

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.

SLC22A6 SLCO2A1 GLYCTK GRIA4 MFSD4B

1.00e-0419781521386911
Pubmed

Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.

CACNA1A GRIA2 GRIA4

1.05e-043981324095980
Pubmed

Molecular constituents of neuronal AMPA receptors.

GRIA2 GRIA4

1.12e-04781215883194
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA2 GRIA4

1.12e-04781221368048
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA2 GRIA4

1.12e-04781233981040
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA2 GRIA4

1.12e-04781210407040
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1E CACNA1S

1.12e-04781212900400
Pubmed

Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons.

SLC6A4 GRIA2

1.12e-04781229337309
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1E

1.12e-04781235176221
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA2 GRIA4

1.12e-0478129016303
Pubmed

Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults.

SLC19A1 SLC46A1

1.12e-04781223656756
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA2 GRIA4

1.12e-0478129651535
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA2 GRIA4

1.12e-04781227076426
Pubmed

Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.

SLC19A1 SLC46A1

1.12e-04781218842806
Pubmed

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms.

GRIA2 GRIA4

1.12e-04781211140673
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIA2 GRIA4

1.12e-0478121310861
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC22A6 SLC35A3 SLC9A3 SLC19A1 SLC5A9

1.41e-0421281519521566
Pubmed

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.

SLC22A24 SVOPL

1.49e-04881217714910
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA2 GRIA4

1.49e-04881223217150
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1E CACNA1S

1.49e-04881228330839
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

SLC19A1 SLC46A1

1.49e-04881222365888
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1A GRIA2 GRIA4

1.61e-044581325979088
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR2T27 OR2T35 OR4D1

1.72e-044681332126975
Pubmed

Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.

SLC2A6 SLC2A4

1.91e-04981219554504
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA2 GRIA4

1.91e-04981224292102
Pubmed

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity.

SLC6A4 SLC22A6

1.91e-04981216024787
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA2 GRIA4

1.91e-0498129051806
Cytoband11q12.3

SLC22A6 SLC22A24 ZBTB3

4.27e-053881311q12.3
Cytoband1q44

OR2AK2 OR2T27 OR2T35 OR2T1

4.50e-051108141q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2AK2 OR2T27 OR2T35 OR2T1

8.12e-05128814chr1q44
CytobandEnsembl 112 genes in cytogenetic band chr11q12

SLC22A6 OR5G3 OR8J1 SLC22A24 ZBTB3

3.74e-04345815chr11q12
Cytoband17q11.2

SLC6A4 DHRS13 SLC46A1

9.97e-0411081317q11.2
GeneFamilySolute carriers

SLC6A4 SLC6A7 SLC6A12 SLC22A6 SLC35A3 SLC9A3 SLC52A1 SLC16A9 SLC19A1 SLC2A6 SLCO2A1 SLC5A9 SLC36A3 SLC12A8 SLC10A3 SLC46A1 SLC22A24 SLC12A7 SLC16A7 SLC22A17 SLC2A4

2.86e-193956621752
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA2 GRIA4

7.84e-0546621200
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1E CACNA1S

1.14e-0426663253
GeneFamilyOlfactory receptors, family 8

OR8B12 OR8J1 OR8B8

7.59e-0449663155
GeneFamilyOlfactory receptors, family 2

OR2AK2 OR2T27 OR2T35 OR2T1

7.74e-04113664149
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HSERT

SLC6A4 CACNA1A CACNA1E NALCN TMEM14A GRIA2 GRIA4 GABBR2 SLC22A17

8.51e-06450799M39072
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

SLC22A6 SLC16A9 SLC19A1 SLCO2A1 GLYCTK SLC5A9 SLC46A1 SLC22A24 ZBTB3 SLC12A7 MFSD4B

3.15e-057846711gudmap_developingKidney_e15.5_early proxim tubul_1000
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC6A12 SLC22A6 SLCO2A1 INSRR SLC12A7 SLC2A4

1.01e-0712381664a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A12 SLC22A6 SLCO2A1 INSRR SLC12A7

8.86e-06153815151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A NALCN GDAP1 INSRR GRIA2

2.05e-051828151923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A NALCN GDAP1 INSRR GRIA2

2.05e-0518281569ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP5MC3 SLC6A12 NALCN CHST9 SLC16A7

2.10e-0518381503c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 SLC22A6 SLC16A9 GLYCTK SLC22A24

2.10e-0518381585446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SLC6A7 CACNA1E GRIA2 GABBR2

2.27e-051868157278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SLC6A7 CACNA1E GRIA2 GABBR2

2.71e-05193815be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC16A9 SLCO2A1 NIPAL3 ITM2B S1PR4

2.71e-05193815b6b065b0c2ad31d1488dfa970450b29a8ac1f3aa
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SLC6A7 CACNA1E GRIA2 GABBR2

2.71e-051938150c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SLC6A7 CACNA1E GRIA2 GABBR2

2.71e-051938158689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC16A9 SLCO2A1 NIPAL3 ITM2B S1PR4

2.71e-051938154513e6cb3f86d9cc56e7892fbe11a861335bd179
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC6A12 SLC22A6 INSRR SLC2A4

4.37e-051078144a18261492371d19b8dbd403e197fdf64ef69392
Drugsodium

SLC6A4 SLC6A7 CACNA1S SLC6A12 SLC22A6 SLC9A3 OR2T1 GRIA2 SLC36A3 GRIA4 SLC12A8 SLC10A3 CATSPER3 SLC46A1 GABBR2 SLC2A4

1.50e-079448016CID000000923
DrugAPMPA

CACNA1A CACNA1E GABBR2

1.45e-067803CID000512300
DrugDCG-IV

CACNA1A CACNA1E GRIA2 GRIA4 GABBR2

4.14e-0668805CID000115114
Drug4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid

SLC22A6 SLC19A1 SLC46A1 SLC12A7

6.05e-0634804ctd:D017878
Drug2-amino-4-phosphonobutyric acid

CACNA1A CACNA1E GRIA2 GRIA4 GABBR2

1.73e-0591805CID000002207
DrugVerapamil

SLC6A4 CACNA1A CACNA1S

2.26e-0516803DB00661
DrugNSC 117356

SLC22A6 SLC16A9 SLC19A1 SLCO2A1 DHODH SLC46A1 SLC16A7

2.56e-05246807CID000004112
Druggabapentin

CACNA1A CACNA1E CACNA1S GRIA2 GRIA4 GABBR2

2.92e-05169806CID000003446
Drugcyclothiazide

CACNA1A SLC22A6 GRIA2 GRIA4 GABBR2

3.16e-05103805CID000002910
Drugriluzole

CACNA1A CACNA1E CACNA1S GRIA2 GRIA4 GABBR2

3.44e-05174806CID000005070
Drug13-methoxyibogamine

SLC6A4 CACNA1E GRIA2 GRIA4

3.91e-0554804CID000065749
Druggamma-aminobutyric acid

SLC6A4 CACNA1A CACNA1E CACNA1S SLC6A12 GRIA2 GRIA4 GPRC6A GABBR2

4.26e-05474809CID000000119
Druglamotrigine

CACNA1A CACNA1E CACNA1S GRIA2 GRIA4

5.58e-05116805CID000003878
DrugLY320135

CACNA1A CACNA1E S1PR4

7.03e-0523803CID005311257
Druggadolinium

CACNA1A CACNA1E CACNA1S GRIA2 GRIA4 GPRC6A

7.26e-05199806CID000023982
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

CACNA1A SLC19A1 DHODH ATP9B GABBR2 SLC22A17

7.26e-051998063058_DN
DrugAC 110

CACNA1A CACNA1E

7.28e-054802CID000022860
Drug3-isoxazolol

GRIA2 GRIA4

7.28e-054802CID009964065
Drugsunifiram

GRIA2 GRIA4

7.28e-054802CID004223812
Drug3-pyridazinol 1-oxide

GRIA2 GRIA4

7.28e-054802CID000574311
Drug4-(chloromethyl)-3-methoxy-5-methylisoxazole

GRIA2 GRIA4

7.28e-054802CID011105661
Drugprobenecid

SLC22A6 SLC16A9 SLCO2A1 SLC46A1 SLC16A7

7.37e-05123805CID000004911
DrugAC1L1DXE

SLC6A4 CACNA1A CACNA1E CACNA1S NPY5R SLC52A1 GABBR2

8.79e-05299807CID000002548
Drugbumetanide

SLC6A4 SLC22A6 SLC9A3 SLC12A8 SLC10A3 SLC12A7

9.51e-05209806CID000002471
DrugSulfobromophthalein

SLC22A6 SLC19A1 SLC46A1

1.15e-0427803ctd:D013448
DrugAC1L1YEG

GRIA2 GRIA4

1.21e-045802CID000063114
DrugChicago acid

GRIA2 GRIA4

1.21e-045802CID000065740
DrugCHEBI:570577

GRIA2 GRIA4

1.21e-045802CID011334126
Drug1-BCP

GRIA2 GRIA4

1.21e-045802CID000001370
DrugN-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid

SLC19A1 SLC46A1

1.21e-045802ctd:C568952
Druglometrexol

SLC19A1 SLC46A1

1.21e-045802ctd:C045894
Drugirampanel

GRIA2 GRIA4

1.21e-045802CID003038472
Drugbeta-N-oxalylaminoalanine

GRIA2 GRIA4

1.21e-045802CID000107978
DrugLY395153

GRIA2 GRIA4

1.21e-045802CID000656707
Drug5-h PCA

GRIA2 GRIA4

1.21e-045802CID000129091
Drugethosuximide

CACNA1A CACNA1E CACNA1S GABBR2

1.35e-0474804CID000003291
DrugAC1NUW3V

SLC6A4 GRIA2 GRIA4

1.43e-0429803CID005462126
DrugAC1Q5UBL

SLC6A4 SLC6A12 GRIA2 GRIA4 GABBR2

1.65e-04146805CID000005466
Drug2cmo

GRIA2 GRIA4

1.81e-046802CID006914597
DrugYM928

GRIA2 GRIA4

1.81e-046802CID006918393
Drug3,4-dihydroquinazoline

CACNA1A CACNA1E

1.81e-046802CID000583065
Drugalpha-sialylcholesterol

CACNA1A CACNA1E

1.81e-046802CID000133976
Drugwillardine

CACNA1S GRIA2 GRIA4

1.93e-0432803CID000005123
Drug3-aminopropylphosphinic acid

CACNA1A CACNA1E GABBR2

1.93e-0432803CID006335948
Drugpotassium

CACNA1A SLC6A7 CACNA1E CACNA1S SLC9A3 SLC36A3 SLC12A8 SLC10A3 CATSPER3 GABBR2 SLC12A7 SLC2A4

1.99e-0410088012CID000000813
DrugCNS 1145

CACNA1A CACNA1E CACNA1S

2.11e-0433803CID000190902
DrugIHC-64

CACNA1A CACNA1E CACNA1S

2.11e-0433803CID000162753
Drug6,7-dinitroquinoxaline

GRIA2 GRIA4 GABBR2

2.11e-0433803CID002724608
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1E

2.01e-053772DOID:0111181 (implicated_via_orthology)
Diseaselongitudinal BMI measurement, non-small cell lung carcinoma

CACNA1A SLC16A7

4.02e-054772EFO_0003060, EFO_0005937
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1E

4.02e-054772DOID:6364 (implicated_via_orthology)
Diseasechildhood absence epilepsy (implicated_via_orthology)

CACNA1A NPY5R

1.00e-046772DOID:1825 (implicated_via_orthology)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1E

1.40e-047772DOID:0050951 (implicated_via_orthology)
Diseasemetabolite measurement

SLC6A12 SLC16A9 SLC5A9 SLC22A24 MFSD4B SVOPL ABCG8

6.52e-04560777EFO_0004725
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA2 GRIA4

7.88e-0416772DOID:331 (implicated_via_orthology)
DiseaseDystonia

CACNA1A CACNA1E SLC46A1

1.50e-0386773C0013421
Diseaseapolipoprotein B measurement

SLC6A4 SLC2A6 SLC46A1 ABCA9 ABCG8 TMEM101 SLC2A4

1.73e-03663777EFO_0004615
Diseasesleep duration, low density lipoprotein cholesterol measurement

SLC6A4 DHODH ABCG8

1.76e-0391773EFO_0004611, EFO_0005271
Diseasesystemic mastocytosis

CACNA1E OR51B5

1.94e-0325772MONDO_0016586
Diseasechronic kidney disease (biomarker_via_orthology)

SLC19A1 SLC46A1

2.43e-0328772DOID:784 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
AILIFAIIGLEFYMG

CACNA1A

236

O00555
FRGMGILGLINLVYF

ELMOD2

166

Q8IZ81
LLMYIFAILGFCLFG

CATSPER3

186

Q86XQ3
AILMFAIIGLEFYSG

CACNA1E

231

Q15878
LNEYGFLGLFFGTML

ABCA9

1156

Q8IUA7
YAIYLIVIGLSGGFM

ABCG8

641

Q9H221
YAILGFALSEAMGLF

ATP5MC3

116

P48201
GGAIYIGFISAMLLF

CLDN20

161

P56880
SFLFTMGGLGFIILD

OSTC

91

Q9NRP0
CFLLLLGVYGMGFAG

OR8B8

141

Q15620
YAGLNIFFGMASIGL

RRH

101

O14718
LLLAVGIAAYLGMAY

NCLN

526

Q969V3
ACLFFLILGLTYLGM

LEMD3

481

Q9Y2U8
AYGILMFFAGLGNSL

SLC16A9

431

Q7RTY1
MYFILLFGGTECFLL

OR10A3

101

P58181
ALGGTEALLLGFMSY

OR2AK2

121

Q8NG84
TLVGAEFFLLGLMAY

OR2T1

156

O43869
TLYMNVGGFLVGLFS

SLC46A1

86

Q96NT5
FLMLLGELGVFASYA

NIPAL3

81

Q6P499
GLFIKLGLTYDGMLS

MAGEB16

181

A2A368
LAFMLAGVILGGAYL

ITM2B

61

Q9Y287
EMLILGRFLIGAYSG

SLC2A4

136

P14672
IYQGGILMYGALVLF

ATP9B

1021

O43861
IGIILSLFVMGGVYF

LRP5

1391

O75197
VFYILVGGLGLAMLV

GRIA2

816

P42262
GVFYILVGGLGLAML

GRIA4

816

P48058
FMYISILFGNGTLLL

OR51B5

31

Q9H339
LYIFLGMLGATDIAL

OR52A1

61

Q9UKL2
VLLLGGLFLAYRMGV

SLC10A3

361

P09131
GLFLAYRMGVFILAG

SLC10A3

366

P09131
VGLLAGVGYFAFMLF

GDAP1

326

Q8TB36
QLYLTMGFITGLGLA

SLC16A7

111

O60669
GFLIYLSGNVIMFLG

SLC16A7

246

O60669
TLAGAEFFLLGLMSY

OR2T27

106

Q8NH04
TLIGGEFFLLGLMAY

OR2T35

106

Q8NGX2
MAVFGSLSLYALGLL

SLC2A6

176

Q9UGQ3
IGGFLVDVMNYFLLL

MFSD4B

51

Q5TF39
EGSILAFGTMLGYIA

GPRC6A

746

Q5T6X5
LLLLLGAYGMGFAGA

OR8B12

141

Q8NGG6
FLVLYGLTMAGNLGI

OR8J1

31

Q8NGP2
MFQTGGLIVFYGLLA

BPIFA1

1

Q9NP55
LYLVGFGKAVLGMAA

GLYCTK

81

Q8IVS8
VIFALLGMQLFGGRY

CACNA1S

571

Q13698
GTRLFLGYALVIFEM

INSRR

106

P14616
GGMLSYASIFLFGLD

GABBR2

526

O75899
GGYMLLATGIFQLLA

DUOXA1

206

Q1HG43
FAGAMYILGTIEIFL

SLC12A7

211

Q9Y666
SLMGFLFLLGLYISS

SLC12A8

306

A0AV02
IFAGVLATIMGLYGA

S1PR4

211

O95977
LLGAMVFGYLADRLG

SLC22A6

146

Q4U2R8
MEALLLGAGLLLGAY

DHRS13

1

Q6UX07
LLGGGTVFFLSVMAY

OR4D1

106

Q15615
FLFVYLITLGGNLGM

OR5G3

31

P0C626
YMFLAGLGLLVIVGL

SSR1

211

P43307
LGFLLAGVDLGVYLM

SLC22A17

161

Q8WUG5
YSVGQMLLGGLAFAI

SLC22A24

241

Q8N4F4
TMRLGSIFGLGLAYA

PSMD2

476

Q13200
GLYTFVSLLGFMGNL

NPY5R

46

Q15761
SLYGVFLSGLMGDLQ

SLC9A3

161

P48764
MGDLQIGLLDFLLFG

SLC9A3

171

P48764
ILGGGGLLFASYLMA

DHODH

16

Q02127
GLFLVTEGGMYIFQL

SLC6A12

436

P48065
GLGVGLLRMILEFSY

SLC5A9

496

Q2M3M2
LFGGLDSLLLAVMAY

OR7A17

106

O14581
GGGAFLVPYFLMLAI

SLC6A7

71

Q99884
ILYILLGTLGYMKFG

SLC36A3

296

Q495N2
GYMVFSILFGLLADR

SVOPL

96

Q8N434
SVLIFGVAGLLLFMY

CHST9

16

Q7L1S5
VFGPAFGYLLGSVML

SLCO2A1

216

Q92959
GVLMGLLFGKIGYYL

YIF1B

236

Q5BJH7
SIMGYNFSLLGLLGE

RHD

326

Q02161
GLVGLSLLGMLFGAY

SLC52A1

341

Q9NWF4
ILSIIYFLGAMLDGL

SLC19A1

441

P41440
MDLIGFGYAALVTFG

TMEM14A

1

Q9Y6G1
GMTGFLSFLLQAYLL

TMEM114

121

B3SHH9
GMVADTFGILLEFIY

ZBTB24

81

O43167
LGLLYLIFAAVEGVM

TMEM87B

326

Q96K49
LGFFGSIFGLMGVYI

SLC35A3

211

Q9Y2D2
IFGGIPLFYMELALG

SLC6A4

126

P31645
AGALYLLFSGMEGVL

TMEM87A

336

Q8NBN3
GELMIQLFFVLYGIL

TMEM101

176

Q96IK0
FGLLLDFMYAGQLTL

ZBTB3

126

Q9H5J0
GMFLLLLCYAFAGVV

NALCN

1341

Q8IZF0
SLGLKLGIYADMGNF

NAGA

111

P17050