Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR11H7 OR10V1 GPR143 OR2T34 PTGDR CHRM1 S1PR3 GPR179 OR2T3 S1PR5 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

3.41e-0888415925GO:0004930
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC1 ABCC4 SLC35B3 SLC7A11 SLC26A1 SLC6A13 SLC47A1

5.41e-07611597GO:1901682
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPC1 VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR11H7 OR10V1 GPR143 OR2T34 PTGDR CHRM1 S1PR3 GPR179 NRP2 OR2T3 S1PR5 TAS2R3 CD4 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 ROBO1 OR7A17 OR7A10

8.98e-07135315929GO:0004888
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.30e-0636315914GO:0106310
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC1 ABCC4 SLC7A13 SLC2A8 SLC35B3 CFTR SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1

4.16e-0629315912GO:0008514
GeneOntologyMolecularFunctionolfactory receptor activity

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

9.44e-0643115914GO:0004984
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.39e-0544615914GO:0004674
GeneOntologyMolecularFunctionprotein kinase activity

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 NRP2 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

2.49e-0560015916GO:0004672
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC1 ABCC4 SLC7A13 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1

4.32e-052071599GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC1 ABCC4 SLC7A13 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1

4.49e-052081599GO:0005342
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 NRP2 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 FAM20B DYRK1B MAPK3 MAP4K4

5.24e-0570915917GO:0016773
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC1 ABCC4 CFTR

5.71e-05101593GO:0043225
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC1 ABCC4 SLC7A13 SLC2A8 SLC35B3 CFTR GJC1 APOL1 SLC7A11 AQP7 SLC26A1 SLC39A13 SLC17A5 SLC6A13 SLC38A10 PIEZO2 KCNC1 KCNC2 KCNC4 SLC24A2 SLC18A1 SLC47A1 SLC7A5P1

6.19e-05118015923GO:0022857
GeneOntologyMolecularFunctiontransporter activity

NPC1 ABCC1 ABCC4 SLC7A13 SLC2A8 SLC35B3 CFTR GJC1 APOL1 SLC7A11 AQP7 SLC26A1 SLC39A13 SLC17A5 SLC6A13 SLC38A10 PIEZO2 KCNC1 KCNC2 KCNC4 SLC24A2 SLC18A1 SLC47A1 SLC7A5P1

8.62e-05128915924GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC1 ABCC4 SLC7A13 SLC2A8 SLC35B3 CFTR SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC24A2 SLC18A1 SLC47A1

1.19e-0447715913GO:0022804
GeneOntologyMolecularFunctionantiporter activity

SLC7A13 SLC35B3 SLC7A11 SLC26A1 SLC24A2 SLC18A1 SLC47A1

1.20e-041381597GO:0015297
GeneOntologyMolecularFunctionkinase activity

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 NRP2 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 FAM20B DYRK1B MAPK3 MAP4K4

1.30e-0476415917GO:0016301
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

ABCC1 ABCC4 SLC7A11 SLC6A13

1.32e-04331594GO:0072349
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC7A13 SLC2A8 SLC35B3 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC24A2 SLC18A1 SLC47A1

1.35e-0429615910GO:0015291
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC1 ABCC4 SLC18A1 SLC47A1

1.49e-04341594GO:0042910
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK20 HIPK1 HIPK2 PAPOLB CHEK1 PIGG MAP3K6 PTK2 MAP3K5 NRP2 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 FAM20B DYRK1B MAPK3 MAP4K4

1.75e-0493815919GO:0016772
GeneOntologyMolecularFunctionMAP kinase activity

MAPK14 MAPK15 MAPK3

2.57e-04161593GO:0004707
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNC1 KCNC2 KCNC4

3.10e-04171593GO:0099508
GeneOntologyMolecularFunctionamide transmembrane transporter activity

ABCC1 ABCC4 AQP7 SLC47A1

3.42e-04421594GO:0042887
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC1 ABCC4 CFTR APOL1 SLC26A1 SLC6A13 SLC18A1

4.48e-041711597GO:0015103
GeneOntologyMolecularFunctionMAP kinase kinase kinase kinase activity

MAP4K1 MAP4K4

9.25e-0461592GO:0008349
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

HIPK1 HIPK2 PTK2 NRP2 HIPK3 DYRK1B

1.09e-031451596GO:0004713
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ABCC1 ABCC4 CFTR APOL1 AQP7 SLC26A1 SLC39A13 SLC17A5 SLC6A13 KCNC1 KCNC2 KCNC4 SLC24A2 SLC18A1 SLC47A1

1.09e-0375815915GO:0015318
GeneOntologyMolecularFunctionglutathione transmembrane transporter activity

ABCC1 ABCC4

1.29e-0371592GO:0034634
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNC1 KCNC2 KCNC4

1.40e-03281593GO:0005251
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC7A13 SLC7A11 SLC6A13 SLC38A10 SLC47A1

1.53e-031051595GO:0015171
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC1 ABCC4

1.71e-0381592GO:0015431
GeneOntologyMolecularFunctionsphingosine-1-phosphate receptor activity

S1PR3 S1PR5

1.71e-0381592GO:0038036
GeneOntologyMolecularFunctiontripeptide transmembrane transporter activity

ABCC1 ABCC4

2.19e-0391592GO:0042937
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC1 ABCC4

2.19e-0391592GO:0034040
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A13 SLC7A11 SLC38A10 SLC47A1

2.49e-03711594GO:0015179
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

ABCC1 SLC2A8 SLC47A1

2.92e-03361593GO:0090482
GeneOntologyBiologicalProcesssulfur compound transport

ABCC1 ABCC4 SLC7A13 SLC35B3 SLC7A11 SLC26A1 SLC6A13 SLC47A1

3.63e-08651598GO:0072348
GeneOntologyBiologicalProcesssensory perception

VN1R2 OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 GJC1 GPR143 DRAM2 OR2T34 GPR179 OR2T3 TAS2R3 PIEZO2 OR14A2 OR56B1 TMTC4 OR1I1 OR7D2 OR52N4 LHFPL5 NLGN2 CLDN19 MAPK3 OR7A17 OR7A10

1.94e-07107215926GO:0007600
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 TAS2R3 PIEZO2 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 LHFPL5 OR7A17 OR7A10

2.72e-0658215917GO:0050906
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR11H7 OR10V1 GPR143 OR2T34 PTGDR CHRM1 S1PR3 GPR179 OR2T3 GPR180 S1PR5 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 CCL1 ROBO1 OR7A17 OR7A10

2.74e-06139515928GO:0007186
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

ABCC1 SLC7A13 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1 SLC7A5P1

4.98e-061631599GO:1905039
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

VN1R2 OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

5.34e-0654715916GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

5.49e-0648515915GO:0050907
GeneOntologyBiologicalProcessorganic acid transmembrane transport

ABCC1 SLC7A13 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1 SLC7A5P1

6.07e-061671599GO:1903825
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

6.74e-0643215914GO:0050911
GeneOntologyBiologicalProcessdetection of stimulus

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 PTK2 OR2T3 TAS2R3 PIEZO2 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 LHFPL5 OR7A17 OR7A10

1.21e-0572215918GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

1.37e-0552415915GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

1.54e-0546515914GO:0007608
GeneOntologyBiologicalProcessmodified amino acid transport

ABCC1 ABCC4 SLC7A13 SLC7A11 SLC6A13

2.18e-05441595GO:0072337
GeneOntologyBiologicalProcessglutathione transmembrane transport

ABCC1 ABCC4 SLC7A11

2.45e-0581593GO:0034775
GeneOntologyBiologicalProcesscalcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

CLDN7 CLDN9 CLDN5 CLDN19

4.45e-05261594GO:0016338
GeneOntologyBiologicalProcesspeptide metabolic process

CPD ADAMTS13 SLC7A11 AEBP1 KLK1 KLK2

4.73e-05841596GO:0006518
GeneOntologyBiologicalProcesstripeptide transmembrane transport

ABCC1 ABCC4 SLC7A11

5.18e-05101593GO:0035443
GeneOntologyBiologicalProcesscell junction organization

NRCAM HIPK1 GJC1 NFASC CHD4 CLDN7 SLC7A11 PTK2 CLDN9 NRP2 CDKL5 MAPK14 LRFN2 LRRTM4 C1QA ROBO1 CLDN5 NLGN2 CLDN19 MAP4K4

6.24e-0597415920GO:0034330
GeneOntologyBiologicalProcessglutathione transport

ABCC1 ABCC4 SLC7A11

7.09e-05111593GO:0034635
GeneOntologyBiologicalProcesstripeptide transport

ABCC1 ABCC4 SLC7A11

1.21e-04131593GO:0042939
GeneOntologyBiologicalProcesscell junction assembly

NRCAM HIPK1 GJC1 NFASC CHD4 CLDN7 PTK2 CLDN9 LRRTM4 ROBO1 CLDN5 NLGN2 CLDN19 MAP4K4

1.36e-0456915914GO:0034329
GeneOntologyBiologicalProcesstissue kallikrein-kinin cascade

KLK1 KLK2

1.76e-0431592GO:0002255
GeneOntologyBiologicalProcessorganic anion transport

ABCC1 ABCC4 SLC7A13 SLC2A8 SLC35B3 CFTR SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC38A10 SLC47A1 SLC7A5P1

1.84e-0451515913GO:0015711
GeneOntologyBiologicalProcesstransepithelial transport

ABCC1 CFTR CSF2 CLDN19

2.05e-04381594GO:0070633
GeneOntologyBiologicalProcessregulation of synapse organization

NRCAM CHD4 SLC7A11 PTK2 NRP2 CDKL5 MAPK14 LRFN2 LRRTM4 ROBO1 NLGN2

2.13e-0438715911GO:0050807
GeneOntologyBiologicalProcessvasodilation

GPER1 CFTR PTK2 KLK1 KLK2

2.36e-04721595GO:0042311
GeneOntologyBiologicalProcessregulation of synapse structure or activity

NRCAM CHD4 SLC7A11 PTK2 NRP2 CDKL5 MAPK14 LRFN2 LRRTM4 ROBO1 NLGN2

2.54e-0439515911GO:0050803
GeneOntologyBiologicalProcessoligopeptide transmembrane transport

ABCC1 ABCC4 SLC7A11

2.82e-04171593GO:0035672
GeneOntologyBiologicalProcesscell-cell junction assembly

HIPK1 GJC1 NFASC CLDN7 CLDN9 CLDN5 CLDN19

3.20e-041671597GO:0007043
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC7A13 SLC7A11 SLC6A13 SLC38A10 SLC47A1 SLC7A5P1

3.38e-041201596GO:0003333
GeneOntologyBiologicalProcessglobus pallidus development

KCNC1 KCNC2

3.51e-0441592GO:0021759
GeneOntologyBiologicalProcessbradykinin biosynthetic process

KLK1 KLK2

3.51e-0441592GO:0002936
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC7A13 SLC7A11 SLC38A10 SLC47A1 SLC7A5P1

5.68e-04871595GO:1902475
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC1 ABCC4 CFTR CLDN7 AQP7 SLC26A1 PTK2 SLC17A5 SLC6A13 KCNC2 SLC47A1 CLDN19

7.33e-0632016112GO:0016323
GeneOntologyCellularComponentpostsynaptic membrane

NRCAM GPER1 CNIH2 CHRM1 GPR179 NRP2 LRFN2 KCNC1 KCNC2 KCNC4 LRRTM4 C1QA NLGN2

1.60e-0540516113GO:0045211
GeneOntologyCellularComponentbasal plasma membrane

ABCC1 ABCC4 CFTR CLDN7 AQP7 SLC26A1 PTK2 SLC17A5 SLC6A13 KCNC2 SLC47A1 CLDN19

2.01e-0535416112GO:0009925
GeneOntologyCellularComponentbasal part of cell

ABCC1 ABCC4 CFTR CLDN7 AQP7 SLC26A1 PTK2 SLC17A5 SLC6A13 KCNC2 SLC47A1 CLDN19

3.81e-0537816112GO:0045178
GeneOntologyCellularComponentapical part of cell

CHL1 ABCC1 ABCC4 SLC7A13 CFTR GPR143 DRAM2 SLC7A11 PTK2 DUOX1 KCNC2 LHFPL5 SLC47A1 KLK1 KLK2

5.56e-0559216115GO:0045177
GeneOntologyCellularComponentmain axon

NRCAM NFASC KCNC1 KCNC2 ROBO1 CLDN5

6.52e-05891616GO:0044304
GeneOntologyCellularComponentendoplasmic reticulum membrane

OR7C2 GPER1 OR7C1 TAPBPL CNIH2 TECR SLC35B3 CFTR GJC1 YIPF7 SEC31A PIGG CYP2S1 SLC39A13 MAP3K5 SACM1L YIPF5 THADA CD4 SLC18A1 SURF4 OR7A17 OR7A10

1.49e-04129316123GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

OR7C2 GPER1 OR7C1 TAPBPL CNIH2 TECR SLC35B3 CFTR GJC1 YIPF7 SEC31A PIGG CYP2S1 SLC39A13 MAP3K5 SACM1L YIPF5 THADA CD4 SLC18A1 SURF4 OR7A17 OR7A10

1.59e-04129916123GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

OR7C2 GPER1 OR7C1 TAPBPL CNIH2 TECR SLC35B3 CFTR GJC1 YIPF7 SEC31A PIGG CYP2S1 SLC39A13 MAP3K5 SACM1L YIPF5 THADA CD4 SLC18A1 SURF4 OR7A17 OR7A10

2.17e-04132716123GO:0042175
GeneOntologyCellularComponentneuron projection membrane

GPER1 KCNC1 KCNC2 KCNC4 ROBO1

4.31e-04821615GO:0032589
GeneOntologyCellularComponentaxolemma

KCNC1 KCNC2 ROBO1

5.39e-04211613GO:0030673
GeneOntologyCellularComponentsynaptic membrane

NRCAM GPER1 CNIH2 CHRM1 GPR179 NRP2 LRFN2 KCNC1 KCNC2 KCNC4 LRRTM4 C1QA NLGN2

5.98e-0458316113GO:0097060
GeneOntologyCellularComponenttight junction

NFASC CLDN7 CLDN9 MAPK15 CLDN5 CLDN19

7.35e-041391616GO:0070160
GeneOntologyCellularComponentdendrite membrane

GPER1 KCNC1 KCNC2 KCNC4

9.12e-04561614GO:0032590
GeneOntologyCellularComponentcoated vesicle membrane

SLC2A8 CNIH2 CFTR RNASEK SEC31A CD4 SLC18A1

1.42e-032151617GO:0030662
GeneOntologyCellularComponentapical plasma membrane

ABCC1 ABCC4 SLC7A13 CFTR GPR143 DRAM2 PTK2 DUOX1 KCNC2 LHFPL5 SLC47A1

1.42e-0348716111GO:0016324
GeneOntologyCellularComponentapical junction complex

NFASC CLDN7 CLDN9 MAPK15 CLDN5 CLDN19

1.43e-031581616GO:0043296
GeneOntologyCellularComponentAMPA glutamate receptor complex

CNIH2 SACM1L LRRTM4

1.56e-03301613GO:0032281
GeneOntologyCellularComponentcoated vesicle

SLC2A8 CNIH2 CFTR RNASEK SEC31A YIPF5 CD4 SLC18A1 SURF4

1.95e-033601619GO:0030135
GeneOntologyCellularComponentPML body

HIPK1 HIPK2 HIRA HIPK3 AGAP3

2.84e-031251615GO:0016605
DomainLipome_HGMIC_fus_partner-like

LHFPL1 LHFPL7 LHFPL5 LHFPL6

1.53e-0771544IPR019372
DomainL_HMGIC_fpl

LHFPL1 LHFPL7 LHFPL5 LHFPL6

1.53e-0771544PF10242
DomainGPCR_Rhodpsn

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR10V1 OR2T34 PTGDR CHRM1 S1PR3 OR2T3 S1PR5 TAS2R3 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

2.58e-0769215421IPR000276
DomainProtein_kinase_ATP_BS

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

5.88e-0737915415IPR017441
DomainGPCR_Rhodpsn_7TM

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR10V1 OR2T34 PTGDR CHRM1 S1PR3 OR2T3 S1PR5 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

6.62e-0767015420IPR017452
DomainG_PROTEIN_RECEP_F1_1

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR10V1 OR2T34 PTGDR CHRM1 S1PR3 OR2T3 S1PR5 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

9.35e-0768515420PS00237
DomainG_PROTEIN_RECEP_F1_2

VN1R2 GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR10V1 OR2T34 PTGDR CHRM1 S1PR3 OR2T3 S1PR5 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

1.07e-0669115420PS50262
DomainSer/Thr_kinase_AS

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.59e-0635715414IPR008271
DomainS_TKc

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.69e-0635915414SM00220
DomainPROTEIN_KINASE_ST

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.87e-0636215414PS00108
DomainK_chnl_volt-dep_Kv3

KCNC1 KCNC2 KCNC4

2.19e-0641543IPR003974
DomainNeurofascin/L1/NrCAM_C

CHL1 NRCAM NFASC

2.19e-0641543IPR026966
DomainBravo_FIGEY

CHL1 NRCAM NFASC

2.19e-0641543PF13882
Domain7tm_1

GPR12 GALR1 OR7C2 GPER1 OR7C1 OR2AP1 OR10V1 OR2T34 PTGDR CHRM1 S1PR3 OR2T3 S1PR5 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

3.19e-0667715419PF00001
DomainPkinase

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

3.38e-0638115414PF00069
DomainPROTEIN_KINASE_ATP

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

6.21e-0645915415PS00107
DomainProt_kinase_dom

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.32e-0548915415IPR000719
DomainPROTEIN_KINASE_DOM

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

1.45e-0549315415PS50011
DomainClaudin_CS

CLDN7 CLDN9 CLDN5 CLDN19

2.90e-05221544IPR017974
DomainCLAUDIN

CLDN7 CLDN9 CLDN5 CLDN19

2.90e-05221544PS01346
DomainKinase-like_dom

CDK20 HIPK1 HIPK2 CHEK1 MAP3K6 PTK2 MAP3K5 HIPK3 CDKL5 MAPK14 MAPK15 MAP4K1 DYRK1B MAPK3 MAP4K4

4.33e-0554215415IPR011009
DomainCFTR/ABCC7

ABCC4 CFTR

6.75e-0521542IPR009147
DomainClaudin

CLDN7 CLDN9 CLDN5 CLDN19

7.80e-05281544IPR006187
DomainArfGap

AGAP7P AGAP4 AGAP6 AGAP3

8.99e-05291544SM00105
DomainArfGap

AGAP7P AGAP4 AGAP6 AGAP3

8.99e-05291544PF01412
DomainARFGAP

AGAP7P AGAP4 AGAP6 AGAP3

8.99e-05291544PS50115
DomainArfGAP

AGAP7P AGAP4 AGAP6 AGAP3

8.99e-05291544IPR001164
DomainOlfact_rcpt

OR7C2 OR7C1 OR2AP1 OR10V1 OR2T34 OR2T3 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

1.04e-0439315412IPR000725
DomainMAP_kinase_CS

MAPK14 MAPK15 MAPK3

1.15e-04121543IPR003527
DomainMAPK

MAPK14 MAPK15 MAPK3

1.15e-04121543PS01351
DomainDUF4071

MAP3K6 MAP3K5

2.02e-0431542IPR025136
DomainDUF4071

MAP3K6 MAP3K5

2.02e-0431542PF13281
DomainPMP22_Claudin

CLDN7 CLDN9 CLDN5 CLDN19

3.22e-04401544PF00822
Domain7TM_GPCR_Srsx

GPR12 GALR1 OR2T34 S1PR3 OR2T3 OR56B1

3.32e-041121546SM01381
DomainPMP22/EMP/MP20/Claudin

CLDN7 CLDN9 CLDN5 CLDN19

5.09e-04451544IPR004031
DomainS1P_rcpt

S1PR3 S1PR5

6.65e-0451542IPR004061
DomainCUB

PAMR1 CDCP2 ADAMTS13 NRP2

9.51e-04531544PS01180
DomainABC_membrane

ABCC1 ABCC4 CFTR

9.80e-04241543PF00664
DomainCUB_dom

PAMR1 CDCP2 ADAMTS13 NRP2

1.25e-03571544IPR000859
DomainYip1

YIPF7 YIPF5

1.38e-0371542PF04893
DomainYip1

YIPF7 YIPF5

1.38e-0371542IPR006977
DomainK_chnl_volt-dep_Kv

KCNC1 KCNC2 KCNC4

1.39e-03271543IPR003968
DomainABC_TM1F

ABCC1 ABCC4 CFTR

1.55e-03281543PS50929
DomainABC1_TM_dom

ABCC1 ABCC4 CFTR

1.55e-03281543IPR011527
DomainVG_K_chnl

KCNC1 KCNC2 KCNC4

2.50e-03331543IPR028325
DomainCarboxyPept_regulatory_dom

CPD AEBP1

4.96e-03131542IPR014766
DomainAA_permease_2

SLC7A13 SLC7A11

4.96e-03131542PF13520
Domain-

CPD AEBP1

4.96e-031315422.60.40.1120
DomainAA/rel_permease1

SLC7A13 SLC7A11

4.96e-03131542IPR002293
DomainCarboxylesterase_B_CS

CES4A NLGN2

4.96e-03131542IPR019819
DomainABC_transporter_CS

ABCC1 ABCC4 CFTR

4.99e-03421543IPR017871
DomainCARBOXYLESTERASE_B_2

CES4A NLGN2

5.76e-03141542PS00941
DomainCOesterase

CES4A NLGN2

5.76e-03141542PF00135
DomainCarbesteraseB

CES4A NLGN2

5.76e-03141542IPR002018
DomainCNH

MAP4K1 MAP4K4

5.76e-03141542SM00036
DomainCNH

MAP4K1 MAP4K4

6.61e-03151542PF00780
DomainCNH

MAP4K1 MAP4K4

6.61e-03151542PS50219
DomainCNH_dom

MAP4K1 MAP4K4

6.61e-03151542IPR001180
DomainABC_tran

ABCC1 ABCC4 CFTR

7.25e-03481543PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCC4 CFTR

7.25e-03481543PS50893
DomainABC_TRANSPORTER_1

ABCC1 ABCC4 CFTR

7.68e-03491543PS00211
DomainCUB

PAMR1 CDCP2 NRP2

7.68e-03491543PF00431
DomainCUB

PAMR1 CDCP2 NRP2

8.12e-03501543SM00042
DomainABC_transporter-like

ABCC1 ABCC4 CFTR

8.12e-03501543IPR003439
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 OR7A17 OR7A10

1.62e-0541712314M4072
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

NRCAM NFASC CLDN7 CLDN9 CD4 CLDN5 NLGN2 CLDN19

2.11e-051331238M16476
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A8 SLC35B3 AHCYL2 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC24A2 SLC18A1 SLC47A1

4.41e-0523812310MM15076
PathwayBIOCARTA_MAPK_PATHWAY

MAP3K6 MAP3K5 MAPK14 MAP4K1 MAPK3 MAP4K4

5.18e-05761236MM1433
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A8 SLC35B3 AHCYL2 SLC7A11 SLC26A1 SLC17A5 SLC6A13 SLC24A2 SLC18A1 SLC47A1

6.45e-0524912310M5988
PathwayBIOCARTA_MAPK_PATHWAY

MAP3K6 MAP3K5 MAPK14 MAP4K1 MAPK3 MAP4K4

7.43e-05811236M13863
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR12 GALR1 OR7C2 GPER1 OR7C1 PTGDR CHRM1 OR1I1 OR7A17 OR7A10

9.24e-0526012310M39397
PathwayREACTOME_TIGHT_JUNCTION_INTERACTIONS

CLDN7 CLDN9 CLDN5 CLDN19

1.27e-04301234M17967
PathwayREACTOME_SENSORY_PERCEPTION

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR2T3 TAS2R3 OR14A2 OR56B1 OR1I1 OR7D2 OR52N4 LHFPL5 OR7A17 OR7A10

1.29e-0463612316M41834
PathwayBIOCARTA_CDK5_PATHWAY

MAPK3 KLK1 KLK2

2.20e-04141233MM1457
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

MAP3K5 MAPK14 MAPK3 MAP4K4

2.92e-04371234MM14899
PathwayKEGG_MEDICUS_REFERENCE_TIGHT_JUNCTION_ACTIN_SIGNALING_PATHWAY

CLDN7 CLDN9 CLDN5 CLDN19

2.92e-04371234M47769
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP7P AGAP4 AGAP6 AGAP3

5.90e-089164412640130
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR7C2 OR7C1 OR56B1 OR1I1 OR52N4 OR7A17 OR7A10

6.29e-0874164715081110
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR7C2 OR7C1 OR11H7 OR10V1 OR2T34 OR14A2 OR1I1 OR7D2 OR7A17 OR7A10

1.01e-072191641012213199
Pubmed

Update on the Regulation of HIPK1, HIPK2 and HIPK3 Protein Kinases by microRNAs.

HIPK1 HIPK2 HIPK3

1.03e-073164329793420
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP7P AGAP4 AGAP6 AGAP3

1.53e-0711164415381706
Pubmed

A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice.

LHFPL1 MAPK14 LHFPL5 LHFPL6

2.29e-0712164415905332
Pubmed

Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.

KCNC1 KCNC2 KCNC4

4.10e-074164321912965
Pubmed

Analysis of a human gene homologous to rat ventral prostate.1 protein.

CLDN7 CLDN9 CLDN5

4.10e-07416439441748
Pubmed

Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).

HIPK1 HIPK2 HIPK3

4.10e-074164325630557
Pubmed

Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues.

CLDN7 CLDN9 CLDN5

4.10e-074164326464708
Pubmed

Structural and functional evolution of the L1 family: are four adhesion molecules better than one?

CHL1 NRCAM NFASC

4.10e-074164310662501
Pubmed

Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.

HIPK1 HIPK2 HIPK3

4.10e-074164334785661
Pubmed

gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes.

CD4 MAPK14 MAPK15 MAPK3

4.60e-0714164412239168
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR14A2 OR56B1 OR1I1 OR52N4 OR7A17 OR7A10

7.20e-073401641111875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR14A2 OR56B1 OR1I1 OR52N4 OR7A17 OR7A10

7.20e-073401641111802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR14A2 OR56B1 OR1I1 OR52N4 OR7A17 OR7A10

7.85e-073431641132295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR14A2 OR56B1 OR1I1 OR52N4 OR7A17 OR7A10

8.55e-073461641114611657
Pubmed

Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa.

CFTR MAPK14 MAPK3

1.02e-065164320460375
Pubmed

HIV-Tat elicits microglial glutamate release: role of NAPDH oxidase and the cystine-glutamate antiporter.

SLC7A11 MAPK14 MAPK3

1.02e-065164320849923
Pubmed

Biology of claudins.

CLDN7 CLDN9 CLDN5 CLDN19

1.75e-0619164418480174
Pubmed

Role of p38, ERK1/2, focal adhesion kinase, RhoA/ROCK and cytoskeleton in the adipogenesis of human mesenchymal stem cells.

PTK2 MAPK14 MAPK3

2.04e-066164324331979
Pubmed

Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: involvement of integrin beta3 and focal adhesion kinase.

PTK2 MAPK14 MAPK3

2.04e-066164319656390
Pubmed

Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.

HIPK1 HIPK2 HIPK3

2.04e-066164320579985
Pubmed

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors.

HIPK1 HIPK2 HIPK3

2.04e-06616439748262
Pubmed

Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.

HIPK1 HIPK2 HIPK3

2.04e-066164312529400
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

GALNT14 HIPK1 HIPK2 CPD PTK2 SACM1L HIPK3 MAPK14 KCNC4 MAP4K1 CES4A ADAM33 MAPK3 ACSM2A UBE2Q2

2.16e-067301641534857952
Pubmed

Multifunctional strands in tight junctions.

CLDN7 CLDN9 CLDN5 CLDN19

2.68e-0621164411283726
Pubmed

Claudin-based barrier in simple and stratified cellular sheets.

CLDN7 CLDN9 CLDN5 CLDN19

2.68e-0621164412231346
Pubmed

Tight junction proteins.

CLDN7 CLDN9 CLDN5 CLDN19

2.68e-0621164412475568
Pubmed

Tight junctions of the blood-brain barrier.

CLDN7 CLDN9 CLDN5 CLDN19

2.68e-0621164410690502
Pubmed

The roles of claudin superfamily proteins in paracellular transport.

CLDN7 CLDN9 CLDN5 CLDN19

2.68e-0621164411247307
Pubmed

Novel function of LHFPL2 in female and male distal reproductive tract development.

LHFPL1 LHFPL5 LHFPL6

3.55e-067164326964900
Pubmed

EphB regulates L1 phosphorylation during retinocollicular mapping.

CHL1 NRCAM NFASC

3.55e-067164322579729
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR7C2 OR7C1 OR7A17 OR7A10

3.94e-0623164410706615
Pubmed

The claudins.

CLDN7 CLDN9 CLDN5 CLDN19

3.94e-0623164419706201
Pubmed

Structure and function of claudins.

CLDN7 CLDN9 CLDN5 CLDN19

3.94e-0623164418036336
Pubmed

Direct phosphorylation of proliferative and survival pathway proteins by RET.

PTK2 MAPK14 MAPK3

5.67e-068164316153436
Pubmed

Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation.

CLDN7 CLDN9 CLDN5 CLDN19

6.57e-0626164422275141
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP7P AGAP4 AGAP6

1.21e-0510164320664521
Pubmed

Expression of claudins in murine tooth development.

CLDN7 CLDN9 CLDN5

1.65e-0511164317075866
Pubmed

Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells.

CD4 MAPK14 MAPK3

1.65e-0511164323742646
Pubmed

MAP4K4 is involved in the neuronal development of retinal photoreceptors.

MAPK14 MAPK3 MAP4K4

2.20e-0512164337290629
Pubmed

Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.

HIPK1 HIPK2 HIPK3

2.20e-0512164316537918
Pubmed

A role for Nr-CAM in the patterning of binocular visual pathways.

CHL1 NRCAM NFASC

2.20e-0512164316701205
Pubmed

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells.

GPER1 PTK2

2.21e-052164230728047
Pubmed

Activation of focal adhesion kinase via M1 muscarinic acetylcholine receptor is required in restitution of intestinal barrier function after epithelial injury.

CHRM1 PTK2

2.21e-052164224365239
Pubmed

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma.

ABCC1 ABCC4

2.21e-052164224024181
Pubmed

Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites.

NRCAM NFASC

2.21e-05216428922386
Pubmed

Developmental expression of potassium-channel subunit Kv3.2 within subpopulations of mouse hippocampal inhibitory interneurons.

KCNC1 KCNC2

2.21e-052164212000114
Pubmed

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.

SACM1L MAPK14

2.21e-052164218299350
Pubmed

A membrane protein enriched in endoplasmic reticulum exit sites interacts with COPII.

YIPF7 YIPF5

2.21e-052164211489904
Pubmed

Abnormal axonal guidance and brain anatomy in mouse mutants for the cell recognition molecules close homolog of L1 and NgCAM-related cell adhesion molecule.

CHL1 NRCAM

2.21e-052164218588951
Pubmed

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines.

ABCC1 ABCC4

2.21e-052164233081264
Pubmed

Kv3.1-containing K(+) channels are reduced in untreated schizophrenia and normalized with antipsychotic drugs.

KCNC1 KCNC2

2.21e-052164223628987
Pubmed

Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.

MAPK14 MAPK3

2.21e-052164218854640
Pubmed

GOLPH3 promotes tumor malignancy via inhibition of ferroptosis by upregulating SLC7A11 in cholangiocarcinoma.

GOLPH3 SLC7A11

2.21e-052164238390729
Pubmed

Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.

MAP3K5 MAPK14

2.21e-052164216400028
Pubmed

Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms.

MAP3K5 MAPK14

2.21e-052164232544093
Pubmed

Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans.

KLK1 KLK2

2.21e-052164211130770
Pubmed

H2O2 stimulates cystic fibrosis transmembrane conductance regulator through an autocrine prostaglandin pathway, using multidrug-resistant protein-4.

ABCC4 CFTR

2.21e-052164223742099
Pubmed

K(+) channel expression distinguishes subpopulations of parvalbumin- and somatostatin-containing neocortical interneurons.

KCNC1 KCNC2

2.21e-052164210531438
Pubmed

Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.

HIPK1 HIPK2

2.21e-052164220231426
Pubmed

Expression pattern of claudins 5 and 7 distinguishes solid-pseudopapillary from pancreatoblastoma, acinar cell and endocrine tumors of the pancreas.

CLDN7 CLDN5

2.21e-052164219194274
Pubmed

Localization of human glandular kallikrein-1 gene to chromosome 19q13.3-13.4 by in situ hybridization.

KLK1 KLK2

2.21e-05216421783409
Pubmed

Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.

MAPK14 MAPK3

2.21e-052164215256218
Pubmed

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

MAP3K6 MAP3K5

2.21e-052164219214184
Pubmed

Redundant role of ASK1-mediated p38MAPK activation in human platelet function.

MAP3K5 MAPK14

2.21e-052164231917191
Pubmed

A unique role for Kv3 voltage-gated potassium channels in starburst amacrine cell signaling in mouse retina.

KCNC1 KCNC2

2.21e-052164215317859
Pubmed

Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase.

MAPK14 MAPK3

2.21e-052164211238443
Pubmed

Spatial and temporal expression of the myometrial mitogen-activated protein kinases p38 and ERK1/2 in the human uterus during pregnancy and labor.

MAPK14 MAPK3

2.21e-052164215784503
Pubmed

Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder.

KCNC1 KCNC2

2.21e-052164231732108
Pubmed

Apoptosis signal-regulating kinase 1 mediates striatal degeneration via the regulation of C1q.

MAP3K5 C1QA

2.21e-052164226728245
Pubmed

ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney.

MAP3K5 MAPK14

2.21e-052164225298527
Pubmed

ERK and p38 MAPK signaling pathways negatively regulate CIITA gene expression in dendritic cells and macrophages.

MAPK14 MAPK3

2.21e-052164216785500
Pubmed

Structural basis for the interaction between focal adhesion kinase and CD4.

PTK2 CD4

2.21e-052164218078954
Pubmed

Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophy.

MAP3K5 MAPK14

2.21e-052164218195174
Pubmed

Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.

CHEK1 MAPK14

2.21e-052164218642443
Pubmed

Localization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testis.

ABCC1 ABCC4

2.21e-052164224130369
Pubmed

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.

MAP3K6 MAP3K5

2.21e-052164217210579
Pubmed

Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7.

CLDN7 MAPK14

2.21e-052164218667601
Pubmed

Fast delayed rectifier potassium current: critical for input and output of the circadian system.

KCNC1 KCNC2

2.21e-052164221414897
Pubmed

MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.

MAP3K6 MAP3K5

2.21e-05216429875215
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP7P AGAP4 AGAP6

2.84e-0513164327713690
Pubmed

FGF signalling regulates bone growth through autophagy.

GOLPH3 SEC31A MAPK14 MAPK3

3.10e-0538164426595272
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

PTK2 MAPK14 MAP4K1 MAPK3 MAP4K4

3.51e-0578164517192257
Pubmed

Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.

CLDN7 CLDN9 CLDN5

3.61e-0514164315366020
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP7P AGAP4 AGAP6

3.61e-0514164322453919
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

TECR CFTR NFASC CDKL5 NLGN2 MAPK3 AGAP7P AGAP4 AGAP6 AGAP3

4.07e-054301641032581705
Pubmed

LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.

ABCC1 ABCC4 SLC47A1

4.49e-0515164328112518
Pubmed

Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland.

CLDN7 CLDN9 CLDN5 CLDN19

5.10e-0543164434737342
Pubmed

Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development.

PTK2 MAPK14 MAPK3

5.51e-0516164320823064
Pubmed

The human olfactory receptor gene family.

OR7C2 OR7C1 OR2AP1 OR11H7 OR10V1 OR2T34 OR56B1 OR7D2 OR52N4 OR7A17 OR7A10

5.64e-055411641114983052
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

NPC1 ABCC1 P4HA2 ABCC4 EDC3 CPD PIGG SLC7A11 SLC39A13 SACM1L NRP2 GPR180 THADA SURF4 FAM20B ROBO1 ST6GALNAC4

5.73e-0512011641735696571
Pubmed

The DNA sequence and biology of human chromosome 19.

OR7C2 OR7C1 S1PR5 OR1I1 DYRK1B OR7A17 KLK2 OR7A10

6.52e-05284164815057824
Pubmed

The Macrophage Activation Induced by Bacillus thuringiensis Cry1Ac Protoxin Involves ERK1/2 and p38 Pathways and the Interaction with Cell-Surface-HSP70.

MAPK14 MAPK3

6.61e-053164228608568
Pubmed

p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization.

MAPK14 MAPK3

6.61e-053164221816898
Pubmed

ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts.

MAPK14 MAPK3

6.61e-053164220155832
Pubmed

Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.

KLK1 KLK2

6.61e-053164219164804
Pubmed

Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium.

KLK1 KLK2

6.61e-053164217465807
Pubmed

Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

ABCC1 ABCC4

6.61e-053164216156793
InteractionP2RY8 interactions

NPC1 PLEKHG4 GOLPH3 PIGG CYP2S1 SACM1L YIPF5 THADA FAM20B

7.55e-061791499int:P2RY8
Cytoband19p13.12

TECR OR1I1 OR7A17 OR7A10

3.18e-0550164419p13.12
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CLPP OR7C2 NRTN OR7C1 TECR S1PR5 OR1I1 OR7D2 OR7A17 OR7A10 FBN3

1.50e-0479716411chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr7q34

HIPK2 TAS2R3 TRBV10-3 TRBV7-7 TRBV7-6

5.58e-041851645chr7q34
GeneFamilySolute carriers

SLC7A13 SLC2A8 SLC35B3 SLC7A11 SLC26A1 SLC39A13 SLC35F4 SLC17A5 SLC6A13 SLC38A10 SLC24A2 SLC18A1 SLC47A1

2.25e-0639512013752
GeneFamilyClaudins

CLDN7 CLDN9 CLDN5 CLDN19

1.48e-05231204488
GeneFamilyArfGAPs

AGAP7P AGAP4 AGAP6 AGAP3

6.51e-05331204395
GeneFamilyMitogen-activated protein kinases

MAPK14 MAPK15 MAPK3

7.77e-05131203651
GeneFamilyATP binding cassette subfamily C

ABCC1 ABCC4 CFTR

7.77e-05131203807
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6 AGAP3

1.81e-041712031291
GeneFamilyMitogen-activated protein kinase kinase kinase kinases

MAP4K1 MAP4K4

4.31e-0451202655
GeneFamilySphingosine 1-phosphate receptors|CD molecules

S1PR3 S1PR5

4.31e-0451202206
GeneFamilyYip1 domain containing

YIPF7 YIPF5

8.98e-0471202105
GeneFamilyOlfactory receptors, family 7

OR7C2 OR7C1 OR7D2 OR7A17 OR7A10

9.40e-041131205154
GeneFamilyPotassium voltage-gated channels

KCNC1 KCNC2 KCNC4

2.36e-03401203274
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4 AFAP1L1 AGAP7P AGAP4 AGAP6 AGAP3

2.53e-032061206682
GeneFamilyFibronectin type III domain containing

CHL1 NRCAM NFASC LRFN2 ROBO1

4.29e-031601205555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 NRCAM NFASC LRFN2 ROBO1

4.41e-031611205593
GeneFamilyKallikreins

KLK1 KLK2

4.93e-03161202616
CoexpressionHALLMARK_APICAL_JUNCTION

NRTN NFASC CLDN7 PTK2 CLDN9 MAPK14 CLDN5 NLGN2 CLDN19

3.88e-062001599M5915
CoexpressionCHYLA_CBFA2T3_TARGETS_DN

P4HA2 AHCYL2 PGAP6 PTK2 NTN4 AGAP7P KLK1 KLK2 AGAP4 AGAP6

5.02e-0626315910MM1295
CoexpressionDESCARTES_ORGANOGENESIS_CONNECTIVE_TISSUE_PROGENITOR

COL6A2 ARSJ PAMR1 LHFPL1 ADAM33

2.10e-05551595MM3666
CoexpressionGSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN

CHL1 CYP2S1 MAPK15 CSF2 KCNC2 CCL1 ADAM33 SEC14L5

3.17e-052001598M7773
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN

HIPK2 GOLPH3 AHCYL2 MAP3K6 SLC7A11 PTK2 ELMO2 ST6GALNAC4

3.17e-052001598M6662
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000

SLC7A13 NRCAM PAMR1 GPER1 HIPK2 CPD CLDN7 PGAP6 SLC26A1 CLDN9 AFAP1L1 NRP2 HIPK3 SLC6A13 NTN4 SLC38A10 KCNC2 SLC47A1 CLDN5 ACSM2A

4.80e-0781114220gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500

NRCAM GPER1 HIPK2 CPD CLDN7 PGAP6 CLDN9 AFAP1L1 HIPK3 NTN4 KCNC2 SLC47A1 CLDN5 ACSM2A

6.08e-0740614214gudmap_developingKidney_e15.5_S-shaped body_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_100

NRCAM HIPK2 KCNC2 SLC47A1 CLDN5 ACSM2A

1.73e-05811426gudmap_developingKidney_e15.5_S-shaped body_100
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

4.76e-081951649d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

5.19e-0819716496d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC YIPF7 S1PR3 PIEZO2 AEBP1 LHFPL6

3.60e-071801648280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC YIPF7 S1PR3 PIEZO2 AEBP1 LHFPL6

3.60e-071801648fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A2 NRCAM GJC1 NFASC ADARB2 KCNC4 LRRTM4 LHFPL6

4.81e-071871648a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC S1PR3 MAP3K5 NRP2 AEBP1 LHFPL6

5.65e-071911648806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

COL6A2 PAMR1 GPER1 GJC1 NFASC S1PR3 AEBP1 LHFPL6

6.36e-071941648d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

6.36e-071941648240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

6.36e-071941648ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC MAP3K5 PIEZO2 AEBP1 LHFPL6 ROBO1

6.36e-07194164890efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC MAP3K5 PIEZO2 AEBP1 LHFPL6 ROBO1

6.36e-071941648df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

6.61e-07195164844d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

P4HA2 ABCC4 ARSJ CFTR CLDN7 VARS2 NTN4 SLC38A10

7.41e-071981648285f729140b1df029c24f6ca1d2438470ac51794
ToppCellmetastatic_Brain-Fibroblasts|metastatic_Brain / Location, Cell class and cell subclass

COL6A2 PAMR1 GPER1 GJC1 S1PR3 PIEZO2 AEBP1 LHFPL6

7.70e-07199164863eb2106bb6e2e33d020628583536c8d96662c84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFASC ADARB2 PTK2 S1PR5 PIEZO2 TMTC4 SLC24A2 SEC14L5

8.00e-072001648acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 GALNT14 NFASC ADARB2 KCNC1 C1QA UBE2Q2

2.20e-061601647f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL6A2 PTGDR SLC7A11 SLC6A13 PIEZO2 AEBP1 SLC47A1

4.45e-061781647cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADARB2 SLC35F4 LHFPL6 ROBO1 SLC47A1 ADAM33 FBN3

4.96e-0618116477846c7b33d1b89364c5a704edaa86520db731c89
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

VN1R2 COL6A2 GJC1 NFASC AEBP1 KCNC4 ADAM33

5.15e-06182164746c213597445b1f4f09dc367f27702d24b201daf
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL6A2 PTGDR SLC7A11 SLC6A13 AEBP1 SLC47A1 MANSC4

5.53e-061841647235890e8b424f4386b6ea52d173d20a00898df73
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 P4HA2 SLC7A13 AQP7 SLC6A13 SLC47A1 ACSM2A

5.53e-0618416479434731f651820b05335085582960f08fbf895de
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PAMR1 S1PR3 C17orf58 NRP2 AEBP1 LHFPL6

6.59e-061891647c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PAMR1 S1PR3 C17orf58 NRP2 AEBP1 LHFPL6

6.59e-0618916472a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

GJC1 HIPK2 NFASC S1PR3 PTK2 CD4 LHFPL6

6.59e-061891647f4865b7db16de15120504147a8016ac522ad242a
ToppCellmoderate-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

COL6A2 NRCAM GJC1 GPR143 NRP2 AEBP1 LHFPL6

6.59e-06189164722a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC S1PR3 MAP3K5 NRP2 AEBP1 ROBO1

6.59e-061891647c734e5693808a0333139e87bd5be2597a9252afe
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A2 PAMR1 S1PR3 C17orf58 NRP2 AEBP1 LHFPL6

6.59e-0618916475a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 GALNT14 ABCC4 HIPK2 NTN4 AEBP1 CLDN19

6.82e-061901647b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC ADARB2 S1PR3 PIEZO2 LRRTM4 LHFPL6

6.82e-0619016472306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PAMR1 S1PR3 C17orf58 NRP2 AEBP1 LHFPL6

6.82e-0619016479cd147a174017ebda23cc47b6d4552d898acd092
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC ADARB2 S1PR3 PIEZO2 LRRTM4 LHFPL6

6.82e-0619016471f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC S1PR3 MAP3K5 PIEZO2 AEBP1 LHFPL6

7.30e-0619216474022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 COL6A2 NRCAM PIEZO2 AEBP1 LHFPL6 ROBO1

7.30e-0619216476f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 COL6A2 NRCAM PIEZO2 AEBP1 LHFPL6 ROBO1

7.30e-0619216473d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHL1 COL6A2 NRCAM S1PR3 PIEZO2 AEBP1 LHFPL6

7.30e-0619216474e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL6A2 P4HA2 SLC2A8 S1PR3 AEBP1 ROBO1 NLGN2

7.55e-0619316471b29525c5936d1b779253b8c20f059fa091c6127
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GALNT14 GPER1 GJC1 S1PR3 CDKL5 PIEZO2 LHFPL6

7.81e-06194164778dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC S1PR3 MAP3K5 AEBP1 LHFPL6

8.08e-061951647d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 MAP3K5 PIEZO2 LHFPL6

8.08e-061951647803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC PTGDR AEBP1 LHFPL6 ADAM33

8.08e-0619516473c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 MAP3K5 PIEZO2 LHFPL6

8.08e-0619516474f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 S1PR3 PIEZO2 AEBP1

8.35e-061961647a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CDK20 COL6A2 S1PR3 PIEZO2 AEBP1 ADAM33 NLGN2

8.35e-061961647614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC ADARB2 S1PR3 PIEZO2 AEBP1

8.35e-0619616473e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL6A2 GPER1 GJC1 RNASEK S1PR3 SLC6A13 LHFPL6

8.35e-06196164712d9028f90c057c6e5cff00301793fa550e86c5a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TECR NFASC PTK2 S1PR5 SLC24A2 CES4A SEC14L5

8.63e-061971647032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCC4 ARSJ CFTR CLDN7 VARS2 NTN4 SLC38A10

8.63e-0619716471485933986921ff45669d9b7501c8d17050b3e97
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GALNT14 COL6A2 PAMR1 GPER1 GJC1 S1PR3 LHFPL6

8.63e-06197164712370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC ADARB2 S1PR3 MAP3K5 PIEZO2 LHFPL6

8.63e-061971647b349f8e96d61a4c296af64711e11fc44459a9413
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 GJC1 NFASC PTK2 NTN4 AEBP1 ADAM33

8.63e-061971647da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NPC1 TECR NFASC S1PR5 TMTC4 SLC24A2 SEC14L5

8.63e-06197164754fb207638e211f8efdb13003ae62a6b1f003b09
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAMR1 GPER1 OR7C1 GJC1 S1PR3 SLC6A13 KCNC4

8.63e-0619716472872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 NFASC ADARB2 S1PR3 MAP3K5 PIEZO2 LHFPL6

8.63e-061971647c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 NRCAM PAMR1 NTN4 LHFPL6 ROBO1 ADAM33

8.92e-061981647ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

COL6A2 PAMR1 NFASC ADAMTS13 S1PR3 AEBP1 LHFPL6

8.92e-061981647bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL6A2 PAMR1 GPR143 ADAMTS13 LRRTM4 LHFPL6 ROBO1

9.22e-06199164738cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFASC PTK2 S1PR5 PIEZO2 TMTC4 SLC24A2 SEC14L5

9.22e-061991647214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 NRCAM GJC1 ADARB2 PTK2 LRRTM4 LHFPL6

9.22e-061991647000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCC4 ARSJ CFTR VARS2 NRP2 NTN4 SLC38A10

9.53e-062001647e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 NRCAM GJC1 ADARB2 PTK2 LRRTM4 LHFPL6

9.53e-062001647911db29f254bb697610e720ba78816e2c7f57933
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 GJC1 PTK2 NTN4 AEBP1 LHFPL6 ADAM33

9.53e-0620016475c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCellproximal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 GJC1 PTK2 NTN4 AEBP1 LHFPL6 ADAM33

9.53e-062001647870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFASC PTK2 S1PR5 PIEZO2 TMTC4 SLC24A2 SEC14L5

9.53e-062001647091a18d6efed81cab99955c3047f172170f70476
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFASC PTK2 S1PR5 PIEZO2 TMTC4 SLC24A2 SEC14L5

9.53e-0620016473b8513defe25262ab4b492345b2628570eaefd17
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial|GW26 / Sample Type, Dataset, Time_group, and Cell type.

COL6A2 PAMR1 GPER1 S1PR3 SLC6A13 CD4 AEBP1

9.53e-0620016478b80811a0ec28d1d763c10b095d1969bccbe82d4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial-Proteoglycan-expressing_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

COL6A2 PAMR1 GPER1 S1PR3 SLC6A13 CD4 AEBP1

9.53e-06200164752ec80f3922ae6ee3565d5993c2fc56bb3a3199a
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

COL6A2 ABCC4 PAMR1 GPR143 ADAMTS13 NRSN2 LHFPL6

9.53e-062001647a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 GJC1 PTK2 NTN4 AEBP1 LHFPL6 ADAM33

9.53e-06200164722892afca3666e944102c231b3f10340d8391364
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CHL1 GALNT14 GPR12 NRTN ADARB2 CCL1

1.84e-0514816465e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHL1 GALNT14 NFASC ADARB2 KCNC1 C1QA

1.84e-0514816465983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HSF2BP PTGDR SLC6A13 SLC47A1 MANSC4 SLC66A3

2.22e-051531646151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_large-bowel / Manually curated celltypes from each tissue

COL6A2 GPR12 PTGDR S1PR5 TRBV10-3 NLGN2

2.57e-051571646d85304af4cd3b8aaedc5362a8223537e1b9dbec2
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A13 ADAMTS13 AQP7 GPR179 SLC6A13 SLC47A1

3.06e-051621646de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GALR1 CFTR ADARB2 C17orf58 NRP2 LHFPL5

3.17e-051631646ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CLDN7 DUOX1 KCNC2 CCL1 CLDN5

3.39e-0516516463f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

AFAP1L1 NRP2 PIEZO2 OR7D2 LHFPL6 CLDN5

3.63e-05167164697d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

GPR12 CYP2S1 ADARB2 ZFYVE28 NRSN2 LHFPL5

3.63e-0516716469efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

GPR12 CYP2S1 ADARB2 ZFYVE28 NRSN2 LHFPL5

3.63e-051671646904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ARSJ CFTR KCNC4 KLK1 FBN3

3.63e-051671646edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 MAP3K5 LHFPL6 ADAM33 KLK1

3.75e-0516816464b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL6A2 GPER1 GJC1 PAPOLB S1PR3 SLC6A13

4.14e-051711646a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

COL6A2 NRCAM GJC1 ADARB2 LRRTM4 LHFPL6

4.14e-051711646080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 PAMR1 NFASC MAP3K5 ADAM33 KLK1

4.14e-0517116465d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NRCAM NRTN CHEK1 ADARB2 AFAP1L1 SEC14L5

4.14e-051711646121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC S1PR3 PIEZO2 AEBP1 LHFPL6 ADAM33

4.28e-0517216461ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

NRCAM GJC1 ADARB2 KCNC4 LRRTM4 LHFPL6

4.28e-051721646858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC S1PR3 PIEZO2 AEBP1 LHFPL6 ADAM33

4.28e-051721646ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADARB2 CCL1 ROBO1 SLC47A1 ADAM33 FBN3

4.56e-05174164693a0dd37d648fcb29654be70f631eee2915f682e
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL6A2 NRCAM GJC1 GPR143 AEBP1 LHFPL6

4.71e-051751646f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPER1 TTLL9 YIPF7 CHEK1 CYP2S1 LHFPL6

5.02e-051771646cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 GPER1 MAP3K6 CHRM1 AFAP1L1 CLDN5

5.02e-0517716465ff8dcfb030312126695d53a026d2e104a401b83
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

P4HA2 SLC7A13 AQP7 SLC6A13 SLC47A1 ACSM2A

5.02e-0517716462f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 AFAP1L1 NRP2 LHFPL6 ROBO1 CLDN5

5.02e-0517716468ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPER1 TTLL9 YIPF7 CHEK1 CYP2S1 LHFPL6

5.18e-05178164604bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A2 NRCAM GJC1 ADARB2 SLC39A13 LHFPL6

5.34e-051791646dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNIH2 NFASC LHFPL1 MAPK15 LRRTM4 NLGN2

5.51e-0518016469db9899ca42455310e9b63df523fe6c4780abfb7
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NRCAM PAMR1 AEBP1 SLC24A2 LRRTM4 ROBO1

5.51e-05180164601f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 NRCAM GJC1 PAPOLB NFASC AEBP1

5.68e-05181164635c470988a93381eefa300831aabb813fa1b90bd
ToppCellPericytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 GJC1 NFASC S1PR3 AEBP1 ADAM33

5.68e-051811646ff445a8e56522e57e27405184d123cf905caf8cc
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR12 CYP2S1 CHRM1 ZFYVE28 NRSN2 CD4

5.86e-051821646d41ff834b8fc1d0e23cac7ae261de5f72874e462
DrugSB202474

MAPK14 MAPK15 CSF2 MAPK3

2.12e-06141584CID000005162
Diseaseamphetamine abuse (implicated_via_orthology)

MAP3K6 MAP3K5 SLC18A1

2.60e-0661513DOID:670 (implicated_via_orthology)
DiseaseMASA syndrome (implicated_via_orthology)

CHL1 NRCAM NFASC

4.53e-0671513DOID:0060246 (implicated_via_orthology)
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

1.54e-05101513DOID:1969 (implicated_via_orthology)
DiseaseMetastatic melanoma

PTK2 CDKL5 MAP4K1 DYRK1B

1.71e-04541514C0278883
Diseasechronic obstructive pulmonary disease (is_implicated_in)

ABCC1 CFTR CCL1 ADAM33

3.10e-04631514DOID:3083 (is_implicated_in)
Diseasecolipase measurement

MAPK14 LHFPL5

3.85e-0461512EFO_0801485
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

VARS2 ROBO1

5.37e-0471512DOID:0060475 (implicated_via_orthology)
Diseaseinfluenza A severity measurement

SLC35F4 ZFYVE28

9.15e-0491512EFO_0007743
Diseasecystic fibrosis (implicated_via_orthology)

ABCC4 CFTR

9.15e-0491512DOID:1485 (implicated_via_orthology)
Diseaserectum cancer (is_implicated_in)

CHD4 MAPK14

9.15e-0491512DOID:1993 (is_implicated_in)
Diseaseepilepsy (implicated_via_orthology)

CHL1 NRCAM NFASC C1QA MAP4K4

1.55e-031631515DOID:1826 (implicated_via_orthology)
Diseasesurvival time, Sepsis

SAMD9 SLC35F4

1.66e-03121512EFO_0000714, HP_0100806
DiseaseGastrointestinal Stromal Sarcoma

NPC1 HIPK1 HIPK2

1.81e-03471513C3179349
DiseaseConnective Tissue Diseases

SLC39A13 PIEZO2

1.96e-03131512C0009782
Diseasecholestasis (biomarker_via_orthology)

ABCC4 CFTR ADAMTS13

2.04e-03491513DOID:13580 (biomarker_via_orthology)
DiseaseGastrointestinal Stromal Tumors

NPC1 HIPK1 HIPK2

2.16e-03501513C0238198
Diseasegastric ulcer (implicated_via_orthology)

CFTR MAPK3

2.27e-03141512DOID:10808 (implicated_via_orthology)
DiseaseN,N,N-trimethyl-5-aminovalerate measurement

P4HA2 SLC47A1

2.61e-03151512EFO_0800090
DiseaseDrug habituation

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0013170
DiseaseDrug abuse

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0013146
DiseasePrescription Drug Abuse

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C4316881
DiseaseSubstance-Related Disorders

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0236969
DiseaseDrug Use Disorders

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0013222
DiseaseDrug Dependence

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C1510472
DiseaseSubstance Dependence

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0038580
DiseaseSubstance Use Disorders

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ABCC4 NRCAM CFTR ADARB2

2.93e-031151514C0029231
Diseaselip morphology measurement

GPR12 SACM1L LRRTM4 MAP4K4 AGAP6

2.94e-031891515EFO_0007845
DiseaseSubstance abuse problem

ABCC4 NRCAM CFTR ADARB2

3.03e-031161514C0740858
Diseasecreatinine measurement, glomerular filtration rate

SLC6A13 THADA SLC47A1 UBE2Q2

3.12e-031171514EFO_0004518, EFO_0005208
Diseaseinfant grey matter volume measurement

SLC35F4 SEC14L5

3.77e-03181512EFO_0008368
DiseaseProstatic Neoplasms

ABCC4 SAMD9 AHCYL2 CLDN7 CLDN9 SURF4 ROBO1 MAPK3 KLK2

4.57e-036161519C0033578
DiseaseMalignant neoplasm of prostate

ABCC4 SAMD9 AHCYL2 CLDN7 CLDN9 SURF4 ROBO1 MAPK3 KLK2

4.57e-036161519C0376358

Protein segments in the cluster

PeptideGeneStartEntry
WASLNLGVLMCIECS

AGAP4

466

Q96P64
WASLNLGALMCIECS

AGAP3

651

Q96P47
TALVCLLLAGMWPED

CCL1

6

P22362
DLWSVGCIMGELLNG

CDK20

186

Q8IZL9
TCWSCRVLSGLGLMG

DMAC1

46

Q96GE9
LMGLIWELLQASAFC

CFTR

211

P13569
GWLVLCVLAISLASM

C1QA

6

P02745
VWSCGIVLTAMLAGE

CHEK1

191

O14757
TWNGSLCMRLEVLGC

AEBP1

526

Q8IUX7
MLAEWGACLLLAVAL

CDCP2

1

Q5VXM1
SDTGWILNILCSLME

ACSM2A

261

Q08AH3
STLAIILGTFAACWM

GPR12

251

P47775
SWVVLCTCSGMSGLI

ADAM33

126

Q9BZ11
ITAVGLYEGLWMSCA

CLDN19

41

Q8N6F1
MAVLWRLSAVCGALG

SDHD

1

O14521
LLLAWSALLCMAGGQ

FBN3

16

Q75N90
DLAIDMWSLGCILVE

DYRK1B

291

Q9Y463
DCGWGCTLRTGQMLL

ATG4C

106

Q96DT6
ESSLNCSAGDMLLLW

ADAMTS13

1231

Q76LX8
WASLNLGVLMCIECS

AGAP6

466

Q5VW22
LQLLAMALECWLSLG

PTGDR

121

Q13258
WDGVLLGEQLITMSC

ADARB2

541

Q9NS39
LWFGAECLAAGSIIM

ZFYVE28

101

Q9HCC9
SVLSIWMCREGLLLS

NRTN

16

Q99748
MGFCLALAWTLLVGA

DUOX1

1

Q9NRD9
GGVSWAMLVARTCQL

PAPOLB

246

Q9NRJ5
LWLVMEFCGAGSITD

MAP4K4

101

O95819
LWSCGITAIEMAEGA

MAP4K4

216

O95819
IMSWSLCVELLVGSL

OR10V1

136

Q8NGI7
GLMVALLIWGFDILC

OR52N4

201

Q8NGI2
MWDLVLSIALSVGCT

KLK2

1

P20151
QTWSGMLVGALCALA

KCNC2

446

Q96PR1
AIDMWSLGCVIAELF

HIPK2

381

Q9H2X6
MWFLVLCLALSLGGT

KLK1

1

P06870
ISLISITLSGNMWEC

LRRTM4

301

Q86VH4
DISTQGWFIGLMCAI

CHL1

1076

O00533
GWFIGLMCAIALLTL

CHL1

1081

O00533
TQGWFIGLMCAVALL

NRCAM

1166

Q92823
MVVAELLLLCWGSFL

GPR179

546

Q6PRD1
EAIDMWSLGCVIAEL

HIPK1

371

Q86Z02
IWSVGCIMAELLTGR

MAPK14

206

Q16539
TLGVDMWSLGCILGE

MAPK15

196

Q8TD08
AMGALAGFWILCLLT

ARSJ

26

Q5FYB0
MTARAFWLLCLIVGS

C17orf58

1

Q2M2W7
GVMWGTLTICFSVLV

LHFPL5

26

Q8TAF8
MEATGTWALLLALAL

CYP2S1

1

Q96SQ9
DIWSLGCTVIEMATG

MAP3K6

831

O95382
LVMWAACGVFSIVGA

SLC7A5P1

86

Q8MH63
CWSLTLCLMAQTALG

CES4A

6

Q5XG92
LLVIWCGVSALSMLT

DRAM2

161

Q6UX65
AGIGMRLEVLGCDWT

NRP2

581

O60462
ICQLVLAWLGMGSDL

OR56B1

206

Q8NGI3
ILLLSMGWTSDSLCS

MANSC4

11

A6NHS7
RGLWQTCGELMFSLE

DPP3

141

Q9NY33
IDIWSVGCILAEMLS

MAPK3

226

P27361
WQMCTVVTGAGCALL

LHFPL1

81

Q86WI0
AWLTGMLQLCLFAIT

AQP7

176

O14520
MATDWLGSIVSINCG

EDC3

1

Q96F86
FLGSGAAIWVTILCM

PGAP6

611

Q9HCN3
MGGLRLLAVALTCCW

GPR180

1

Q86V85
MATLLAWVGVSCCEL

NSUN5P1

1

Q3KNT7
AGVLLAICLFWAMIG

NRSN2

126

Q9GZP1
CGLLLGASWMITNLQ

OR1I1

141

O60431
QLIFCSWLGGLMAII

OR2AP1

141

Q8NGE2
SACWVLGMVDGLLLT

OR2T34

151

Q8NGX1
SACWVLGMVDGLLLT

OR2T3

151

Q8NH03
DMWSLGCVIAELFLG

HIPK3

381

Q9H422
MASSLTCTGVIWALL

LHFPL6

1

Q9Y693
SALLMAWFGVLSCVQ

P4HA2

6

O15460
EISFRVWMCGGSLEI

GALNT14

311

Q96FL9
LVTMVLLGCELWSAV

NPC1

1111

O15118
LLGCELWSAVIMCAT

NPC1

1116

O15118
TALLWMEIGISCLAG

ABCC4

226

O15439
DIATQGWFIGLMCAI

NFASC

1211

O94856
GWFIGLMCAIALLVL

NFASC

1216

O94856
CGLLVLGSWCISVMG

OR7C1

141

O76099
LGSWCISVMGSLLET

OR7C1

146

O76099
VGCIWALSIAMASPV

GALR1

156

P47211
MWLQSLLLLGTVACS

CSF2

1

P04141
WSGMLVGALCALAGV

KCNC1

411

P48547
CIWIDGLSALLGKDM

ELMO2

656

Q96JJ3
YGVTGLCLLLNIWEM

GJC1

236

P36383
AWGLATLLCVEGAAM

GPR143

161

P51810
MLQGTCSVLLLWGIL

COL6A2

1

P12110
CLWLEILMGIFIAGT

IFNK

11

Q9P0W0
GATMSALILTACIIW

CPD

1306

O75976
GMWQCLLSDSGQVLL

CD4

366

P01730
WNDCISSGLRGCMLI

GOLPH3

81

Q9H4A6
LLMGHWALGTLACDL

CHRM1

86

P11229
WASLNLGVLMCIECS

AGAP7P

466

Q5VUJ5
MEGAALLRVSVLCIW

APOL1

1

O14791
VLCIWMSALFLGVGV

APOL1

11

O14791
CWLTLMEALHLNLGG

DNAH14

1146

Q0VDD8
QCGLVALWMAGTLLS

C19orf54

131

Q5BKX5
WTLNGLGILVCSMDG

HIRA

336

P54198
MLSSVWVALGLSLTC

LHFPL7

1

Q6ICI0
TIDMAILGSIDWACL

CHD4

856

Q14839
SVDMWSVGCILGELS

CDKL5

191

O76039
ISSWTCLLDLEGLNM

SEC14L5

376

O43304
LGSWLCMILSGQAAD

SLC17A5

336

Q9NRA2
LLIGMCWLIAFTLGA

S1PR3

156

Q99500
IICLLMAGDTWTETL

SACM1L

536

Q9NTJ5
TLAMAAAAWGVSLLL

S1PR5

151

Q9H228
TGCSAGLLMTVGWLL

SPACA1

6

Q9HBV2
DTWICSLLGSLMVGL

SLC39A13

66

Q96H72
IVLGALLLVFCSWMT

SLC38A10

36

Q9HBR0
MWLLALCLVGLAGAQ

NLGN2

1

Q8NFZ4
MTGQLCGILVSLCWL

OR11H7

136

Q8NGC8
MELGCWTQLGLTFLQ

PAMR1

1

Q6UXH9
CGLLVLGSWCISVMG

OR7C2

141

O60412
LGSWCISVMGSLLET

OR7C2

146

O60412
TGVCVLMASVSWAIG

OR14A2

136

Q96R54
GIMLTFWLVALVCAL

ABCC1

136

P33527
AADIWSLGCTIIEMA

MAP3K5

861

Q99683
VRFGALSCWLGEMST

MAP4K1

691

Q92918
IAEDGTMTSLCGDWL

VARS2

416

Q5ST30
TEMGAAACTLLWGVS

HSF2BP

121

O75031
AVLFLCQGTLAMLDW

THADA

306

Q6YHU6
VLMETLGALGAQCRW

AHCYL2

241

Q96HN2
MGTQEGWCLLLCLAL

TAPBPL

1

Q9BX59
VWMLLGALLLSCGST

TAS2R3

131

Q9NYW6
GMCALFSREILNLTW

SLC24A2

221

Q9UI40
MGSCARLLLLWGCTV

NTN4

1

Q9HB63
CWELLASGMATLPGT

PLEKHG4

186

Q58EX7
CGGTTLAMHILWELR

SAMD9

741

Q5K651
CGLLVLASWIMSVLN

OR7A10

141

O76100
WIIMELCTLGELRSF

PTK2

496

Q05397
ASVGLAWLAVGSMCL

SLC2A8

366

Q9NY64
GICVLTNWLMAFLVT

SLC2A8

411

Q9NY64
LSCGLIWMASVSATL

GPER1

176

Q99527
SAAICMSLGLIWFTL

SLC35B3

201

Q9H1N7
AVQLLLVAAWSMGCG

SLURP1

6

P55000
CGLLVLASWMIAALN

OR7A17

141

O14581
CGLLVFVTWLIGVMT

OR7D2

141

Q96RA2
LCLISTFLEDGIRMW

SURF4

31

O15260
SCTSMVLKGIWGLLI

SLC35F4

156

A4IF30
TTLGVMGLWSGIIIC

SLC47A1

431

Q96FL8
MGLWSGIIICTVFQA

SLC47A1

436

Q96FL8
ILEASCSEDMGRWLG

AFAP1L1

491

Q8TED9
CSEDMGRWLGLLLVE

AFAP1L1

496

Q8TED9
IGWAATALLMVGGCL

CLDN5

166

O00501
FSMALLGWVGLVACT

CLDN7

11

O95471
MTLAVLGWLGTLVSC

CLDN9

11

O95484
WCVGQAASMGSLLLA

CLPP

146

Q16740
MFLCAAEWVTLGLNI

CNIH2

81

Q6PI25
VWTLCEMLSILALVG

C15orf32

51

Q32M92
LMDLITLSFWLAGQC

C11orf40

136

Q8WZ69
LCLLWTGHMDAGITQ

TRBV10-3

11

A0A0K0K1G6
VGMSLTIWTVCGVLS

SLC7A11

76

Q9UPY5
WVLLSIFLGAVAMLC

TMTC4

206

Q5T4D3
GALCMELLTKQGWSS

UBE2Q2

301

Q8WVN8
LSTGWFTMILALELC

ST6GALNAC4

211

Q9H4F1
DCVGVGLLIATLMWF

UNC50

121

Q53HI1
ALVWAGTAATCMLVS

SLC26A1

471

Q9H2B4
WDVTMQDLCSGAIGL

PFAS

1091

O15067
CADGDIMEGSVTLWL

FAM20B

211

O75063
DALGWLLALSSMVCI

SLC6A13

531

Q9NSD5
DIGMFIASLTIWLLC

PIEZO2

126

Q9H5I5
EVGSWIGFAIMTQCL

TECR

251

Q9NZ01
MGTSLLCWVVLGFLG

TRBV7-6

1

A0A1B0GX31
MGTSLLCWVVLGFLG

TRBV7-7

1

A0A0K0K1E9
AGIGAACWIILMVFS

ROBO1

901

Q9Y6N7
CLALAMLWIVGILTS

SLC7A13

136

Q8TCU3
MEAALLGLCNWSTLG

SLC66A3

1

Q8N755
MVGIILTAGIIGWCS

YIPF5

206

Q969M3
MEIGSAALTILVECW

ZSWIM8

1316

A7E2V4
VLVMSVFAECLLWSG

TTLL9

231

Q3SXZ7
MCWIGQALIAEAVGS

TTC37

896

Q6PGP7
GIMSSLVIIGWCSLS

YIPF7

231

Q8N8F6
CGLSWLAAGGVMVLA

PIGG

501

Q5H8A4
AACGIVLSAWGVIML

RNASEK

51

Q6P5S7
IAWSMADPELLLSCG

SEC31A

266

O94979
WLCSLIGMLVVGTSL

SLC18A1

366

P54219
VLCLGLMLWASSSIV

VN1R2

271

Q8NFZ6
TWSGMLVGALCALAG

KCNC4

446

Q03721
LVSGTGYDLCVLAMW

LRFN2

481

Q9ULH4