Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	CACNB2 SPATA31A3 ANK3 SPATA31A7 KIF1B WHAMM LMOD2 SPATA31A5 RHAG KRIT1 MAPK8IP3 SPATA31A1 ALMS1 FMN1 MACF1 DAAM2 KIF3C GNAS PLEC TAGLN NLRP5 NIN	1.91e-08	1099	100	22	GO:0008092
GeneOntologyMolecularFunction	actin binding	CACNB2 SPATA31A3 SPATA31A7 WHAMM LMOD2 SPATA31A5 SPATA31A1 FMN1 MACF1 DAAM2 PLEC TAGLN	4.91e-06	479	100	12	GO:0003779
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 MACF1 KIF3C DNAH5 DNAH8	1.30e-05	441	100	11	GO:0016887
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	SHANK1 MPP2 SHANK2	1.95e-05	11	100	3	GO:0098919
GeneOntologyMolecularFunction	microtubule motor activity	KIF1B DYNLRB2 KIF3C DNAH5 DNAH8	2.66e-05	70	100	5	GO:0003777
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 MACF1 KIF3C GNAS DNAH5 DNAH8 AGAP4 AGAP6	3.13e-05	775	100	14	GO:0017111
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	SHANK1 MPP2 SHANK2	3.36e-05	13	100	3	GO:0098879
GeneOntologyMolecularFunction	ATP-dependent activity	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 DYNLRB2 MACF1 KIF3C DNAH5 DNAH8	5.72e-05	614	100	12	GO:0140657
GeneOntologyMolecularFunction	tubulin binding	KIF1B WHAMM KRIT1 ALMS1 FMN1 MACF1 KIF3C GNAS NLRP5 NIN	5.72e-05	428	100	10	GO:0015631
GeneOntologyMolecularFunction	pyrophosphatase activity	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 MACF1 KIF3C GNAS DNAH5 DNAH8 AGAP4 AGAP6	7.38e-05	839	100	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 MACF1 KIF3C GNAS DNAH5 DNAH8 AGAP4 AGAP6	7.48e-05	840	100	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ATAD5 DHX40 KIF1B ATP8B1 DHX30 ATP6V1H ABCD4 MACF1 KIF3C GNAS DNAH5 DNAH8 AGAP4 AGAP6	7.48e-05	840	100	14	GO:0016818
GeneOntologyMolecularFunction	synaptic receptor adaptor activity	SHANK1 SHANK2	1.48e-04	4	100	2	GO:0030160
GeneOntologyMolecularFunction	microtubule binding	KIF1B WHAMM KRIT1 ALMS1 FMN1 MACF1 KIF3C NIN	1.59e-04	308	100	8	GO:0008017
GeneOntologyMolecularFunction	DNA-directed DNA polymerase activity	POLG PRIMPOL REV1	2.59e-04	25	100	3	GO:0003887
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF1B DYNLRB2 KIF3C DNAH5 DNAH8	3.19e-04	118	100	5	GO:0003774
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB2 PFKM	5.13e-04	7	100	2	GO:0008443
GeneOntologyMolecularFunction	structural constituent of postsynapse	SHANK1 MPP2 SHANK2	5.44e-04	32	100	3	GO:0099186
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2A	6.82e-04	8	100	2	GO:0140945
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNLRB2 DNAH5 DNAH8	8.37e-04	37	100	3	GO:0045505
GeneOntologyMolecularFunction	DNA polymerase activity	POLG PRIMPOL REV1	9.05e-04	38	100	3	GO:0034061
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2A	1.09e-03	10	100	2	GO:0140999
GeneOntologyMolecularFunction	structural constituent of synapse	SHANK1 MPP2 SHANK2	1.21e-03	42	100	3	GO:0098918
GeneOntologyMolecularFunction	ionotropic glutamate receptor binding	SHANK1 SHANK2 GNAS	2.25e-03	52	100	3	GO:0035255
GeneOntologyMolecularFunction	microtubule minus-end binding	MACF1 NIN	2.50e-03	15	100	2	GO:0051011
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	SHANK1 MAPK8IP3 SHANK2	2.51e-03	54	100	3	GO:0030159
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	SETD1A DAZAP2 E4F1 NCAPG2 STAT5A STAT5B NCOR2 KMT2A RAD21	2.58e-03	582	100	9	GO:0140297
GeneOntologyMolecularFunction	kinesin binding	KIF1B MAPK8IP3 KIF3C	2.65e-03	55	100	3	GO:0019894
GeneOntologyBiologicalProcess	microtubule-based movement	CFAP47 ANK3 KIF1B SPG11 MAPK8IP3 ENO4 RASGRP1 DYNLRB2 KIF3C DNAH5 DNAH8 HYDIN	4.27e-06	493	99	12	GO:0007018
GeneOntologyBiologicalProcess	positive regulation of natural killer cell differentiation	STAT5A STAT5B RASGRP1	2.29e-05	12	99	3	GO:0032825
GeneOntologyBiologicalProcess	natural killer cell differentiation	STAT5A STAT5B RASGRP1 HECTD1	3.25e-05	38	99	4	GO:0001779
GeneOntologyBiologicalProcess	microtubule-based process	CFAP47 ANK3 KIF1B SPG11 MAPK8IP3 ENO4 RASGRP1 ALMS1 DYNLRB2 MACF1 KIF3C DNAH5 DNAH8 HYDIN NLRP5 NIN	4.18e-05	1058	99	16	GO:0007017
GeneOntologyBiologicalProcess	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	LAMTOR5 DAZAP2	6.82e-05	3	99	2	GO:1905636
GeneOntologyBiologicalProcess	cellular response to hydrostatic pressure	PIK3CA PLEC	6.82e-05	3	99	2	GO:0071464
GeneOntologyBiologicalProcess	development of secondary male sexual characteristics	STAT5A STAT5B	6.82e-05	3	99	2	GO:0046544
GeneOntologyBiologicalProcess	regulation of multicellular organism growth	STAT5A STAT5B ALMS1 PIK3CA GNAS	8.56e-05	93	99	5	GO:0040014
GeneOntologyBiologicalProcess	regulation of natural killer cell differentiation	STAT5A STAT5B RASGRP1	1.34e-04	21	99	3	GO:0032823
GeneOntologyBiologicalProcess	cell-substrate junction assembly	WHAMM FMN1 LRP1 MACF1 PLEC	1.73e-04	108	99	5	GO:0007044
GeneOntologyCellularComponent	sarcolemma	CACNB2 ANK3 RYR1 SGCZ GNAS PLEC FER1L5	3.84e-05	190	101	7	GO:0042383
GeneOntologyCellularComponent	dendrite	EPHB2 SHANK1 MPP2 ANK3 KIF1B SPG11 MAPK8IP3 SHANK2 LRP1 KIF3C GNAS PLEC NIN	2.48e-04	858	101	13	GO:0030425
GeneOntologyCellularComponent	dendritic tree	EPHB2 SHANK1 MPP2 ANK3 KIF1B SPG11 MAPK8IP3 SHANK2 LRP1 KIF3C GNAS PLEC NIN	2.54e-04	860	101	13	GO:0097447
MousePheno	increased circulating mineral level	ACTR8 KIF1B ATP8B1 RHAG RYR1 DHX30 ATP6V1H DYNLRB2 DAAM2 GNAS DNAH5 HECTD1 AGAP4 AGAP6	2.26e-05	626	85	14	MP:0014547
MousePheno	increased mineral level	ACTR8 KIF1B ATP8B1 RHAG RYR1 DHX30 ATP6V1H DYNLRB2 DAAM2 GNAS DNAH5 HECTD1 AGAP4 AGAP6	4.61e-05	668	85	14	MP:0014535
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	3.16e-05	12	100	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	3.16e-05	12	100	3	IPR027970
Domain	P-loop_NTPase	MPP2 CACNB2 ATAD5 DHX40 KIF1B PFKFB2 DHX30 ABCD4 KIF3C GNAS DNAH5 DNAH8 HYDIN GNL3 NLRP5	4.37e-05	848	100	15	IPR027417
Domain	-	MACF1 PLEC	4.20e-04	6	100	2	3.90.1290.10
Domain	SAM_1	EPHB2 SHANK1 SHANK2 BICC1	4.85e-04	68	100	4	PF00536
Domain	Ankyrin_rpt	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6 TCTN2	5.21e-04	262	100	7	IPR002110
Domain	CH	CFAP47 MACF1 PLEC TAGLN	5.41e-04	70	100	4	PF00307
Domain	-	CFAP47 MACF1 PLEC TAGLN	5.71e-04	71	100	4	1.10.418.10
Domain	STAT_TF_DNA-bd_sub	STAT5A STAT5B	5.86e-04	7	100	2	IPR012345
Domain	STAT	STAT5A STAT5B	5.86e-04	7	100	2	IPR001217
Domain	STAT_int	STAT5A STAT5B	5.86e-04	7	100	2	SM00964
Domain	STAT_TF_DNA-bd	STAT5A STAT5B	5.86e-04	7	100	2	IPR013801
Domain	STAT_bind	STAT5A STAT5B	5.86e-04	7	100	2	PF02864
Domain	STAT_int	STAT5A STAT5B	5.86e-04	7	100	2	PF02865
Domain	Plectin	MACF1 PLEC	5.86e-04	7	100	2	PF00681
Domain	-	STAT5A STAT5B	5.86e-04	7	100	2	1.10.532.10
Domain	STAT_alpha	STAT5A STAT5B	5.86e-04	7	100	2	PF01017
Domain	-	STAT5A STAT5B	5.86e-04	7	100	2	1.20.1050.20
Domain	STAT_TF_prot_interaction	STAT5A STAT5B	5.86e-04	7	100	2	IPR013799
Domain	Plectin_repeat	MACF1 PLEC	5.86e-04	7	100	2	IPR001101
Domain	STAT_TF_coiled-coil	STAT5A STAT5B	5.86e-04	7	100	2	IPR015988
Domain	-	STAT5A STAT5B	5.86e-04	7	100	2	2.60.40.630
Domain	PLEC	MACF1 PLEC	5.86e-04	7	100	2	SM00250
Domain	-	MPP2 CACNB2 ATAD5 DHX40 PFKFB2 DHX30 ABCD4 GNAS DNAH5 DNAH8 HYDIN GNL3	6.33e-04	746	100	12	3.40.50.300
Domain	CH	CFAP47 MACF1 PLEC TAGLN	6.34e-04	73	100	4	PS50021
Domain	CH-domain	CFAP47 MACF1 PLEC TAGLN	7.03e-04	75	100	4	IPR001715
Domain	STAT_TF_alpha	STAT5A STAT5B	7.78e-04	8	100	2	IPR013800
Domain	DHC_N1	DNAH5 DNAH8	7.78e-04	8	100	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH8	7.78e-04	8	100	2	IPR013594
Domain	SAM	EPHB2 SHANK1 SHANK2 BICC1	1.28e-03	88	100	4	SM00454
Domain	SAM_DOMAIN	EPHB2 SHANK1 SHANK2 BICC1	1.70e-03	95	100	4	PS50105
Domain	SAM	EPHB2 SHANK1 SHANK2 BICC1	1.83e-03	97	100	4	IPR001660
Domain	-	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6	2.17e-03	248	100	6	1.25.40.20
Domain	ANK	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6	2.31e-03	251	100	6	SM00248
Domain	ANK_REPEAT	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6	2.40e-03	253	100	6	PS50088
Domain	Ankyrin_rpt-contain_dom	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6	2.45e-03	254	100	6	IPR020683
Domain	ANK_REP_REGION	SHANK1 ANK3 KRIT1 HECTD1 AGAP4 AGAP6	2.45e-03	254	100	6	PS50297
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH8	2.48e-03	14	100	2	IPR024317
Domain	Dynein_HC_stalk	DNAH5 DNAH8	2.48e-03	14	100	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH8	2.48e-03	14	100	2	IPR013602
Domain	DHC_N2	DNAH5 DNAH8	2.48e-03	14	100	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH5 DNAH8	2.48e-03	14	100	2	IPR011704
Domain	MT	DNAH5 DNAH8	2.48e-03	14	100	2	PF12777
Domain	AAA_8	DNAH5 DNAH8	2.48e-03	14	100	2	PF12780
Domain	AAA_5	DNAH5 DNAH8	2.48e-03	14	100	2	PF07728
Domain	-	EPHB2 SHANK1 SHANK2 BICC1	2.53e-03	106	100	4	1.10.150.50
Domain	-	RYR1 STAT5A STAT5B RASGRP1 MACF1 NIN	2.80e-03	261	100	6	1.10.238.10
Domain	DHC_fam	DNAH5 DNAH8	2.85e-03	15	100	2	IPR026983
Domain	FH2	FMN1 DAAM2	2.85e-03	15	100	2	PS51444
Domain	Dynein_heavy	DNAH5 DNAH8	2.85e-03	15	100	2	PF03028
Domain	FH2_Formin	FMN1 DAAM2	2.85e-03	15	100	2	IPR015425
Domain	FH2	FMN1 DAAM2	2.85e-03	15	100	2	PF02181
Domain	Dynein_heavy_dom	DNAH5 DNAH8	2.85e-03	15	100	2	IPR004273
Domain	FH2	FMN1 DAAM2	2.85e-03	15	100	2	SM00498
Domain	p53-like_TF_DNA-bd	STAT5A KRIT1 STAT5B	2.87e-03	53	100	3	IPR008967
Domain	Post-SET_dom	SETD1A KMT2A	3.24e-03	16	100	2	IPR003616
Domain	PostSET	SETD1A KMT2A	3.24e-03	16	100	2	SM00508
Domain	POST_SET	SETD1A KMT2A	3.24e-03	16	100	2	PS50868
Domain	SAM/pointed	EPHB2 SHANK1 SHANK2 BICC1	3.61e-03	117	100	4	IPR013761
Domain	DUF1605	DHX40 DHX30	3.66e-03	17	100	2	IPR011709
Domain	OB_NTP_bind	DHX40 DHX30	3.66e-03	17	100	2	PF07717
Domain	HA2	DHX40 DHX30	4.11e-03	18	100	2	SM00847
Domain	HA2	DHX40 DHX30	4.11e-03	18	100	2	PF04408
Domain	Helicase-assoc_dom	DHX40 DHX30	4.11e-03	18	100	2	IPR007502
Domain	EF-hand-dom_pair	RYR1 STAT5A STAT5B RASGRP1 MACF1 NIN	4.46e-03	287	100	6	IPR011992
Domain	CH	MACF1 PLEC TAGLN	5.12e-03	65	100	3	SM00033
Pathway	PID_IL5_PATHWAY	STAT5A STAT5B PIK3CA	5.25e-05	14	76	3	M135
Pathway	BIOCARTA_IL7_PATHWAY	STAT5A STAT5B PIK3CA	8.02e-05	16	76	3	M1296
Pathway	BIOCARTA_IL7_PATHWAY	STAT5A STAT5B PIK3CA	8.02e-05	16	76	3	MM1420
Pathway	REACTOME_SIGNALING_BY_FLT3_ITD_AND_TKD_MUTANTS	STAT5A STAT5B PIK3CA	8.02e-05	16	76	3	M41733
Pathway	REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS	STAT5A STAT5B PIK3CA	1.16e-04	18	76	3	M673
Pathway	REACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS	STAT5A STAT5B PIK3CA	1.37e-04	19	76	3	M41732
Pathway	REACTOME_SIGNALING_BY_KIT_IN_DISEASE	STAT5A STAT5B PIK3CA	1.61e-04	20	76	3	M39002
Pathway	BIOCARTA_PPARA_PATHWAY	STAT5A STAT5B NCOR2 PIK3CA	1.74e-04	52	76	4	M2404
Pathway	BIOCARTA_GLEEVEC_PATHWAY	STAT5A STAT5B PIK3CA	2.47e-04	23	76	3	MM1424
Pathway	BIOCARTA_GLEEVEC_PATHWAY	STAT5A STAT5B PIK3CA	2.47e-04	23	76	3	M7897
Pathway	BIOCARTA_TPO_PATHWAY	STAT5A STAT5B PIK3CA	2.81e-04	24	76	3	M11520
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	2.84e-04	5	76	2	M48987
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	2.84e-04	5	76	2	M48986
Pathway	KEGG_MEDICUS_REFERENCE_PRL_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	2.84e-04	5	76	2	M49006
Pathway	BIOCARTA_TPO_PATHWAY	STAT5A STAT5B PIK3CA	3.18e-04	25	76	3	MM1519
Pathway	REACTOME_SIGNALING_BY_ERYTHROPOIETIN	STAT5A STAT5B PIK3CA	3.18e-04	25	76	3	M27865
Pathway	PID_IL3_PATHWAY	STAT5A STAT5B PIK3CA	3.58e-04	26	76	3	M182
Pathway	BIOCARTA_GH_PATHWAY	STAT5A STAT5B PIK3CA	4.01e-04	27	76	3	M9043
Pathway	REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	STAT5A STAT5B PIK3CA	4.01e-04	27	76	3	MM14712
Pathway	REACTOME_INTERLEUKIN_9_SIGNALING	STAT5A STAT5B	4.24e-04	6	76	2	MM15581
Pathway	REACTOME_INTERLEUKIN_21_SIGNALING	STAT5A STAT5B	4.24e-04	6	76	2	MM15621
Pathway	REACTOME_FLT3_SIGNALING_IN_DISEASE	STAT5A STAT5B PIK3CA	4.48e-04	28	76	3	M41724
Pathway	WP_PDGFRBETA_PATHWAY	STAT5A STAT5B PIK3CA	4.97e-04	29	76	3	M39616
Pathway	REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	STAT5A STAT5B PIK3CA	4.97e-04	29	76	3	M779
Pathway	PID_IL2_STAT5_PATHWAY	STAT5A STAT5B PIK3CA	5.51e-04	30	76	3	M234
Pathway	REACTOME_STAT5_ACTIVATION	STAT5A STAT5B	5.92e-04	7	76	2	M27953
Pathway	KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	5.92e-04	7	76	2	M47581
Pathway	KEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	5.92e-04	7	76	2	M47646
Pathway	KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B	5.92e-04	7	76	2	M47430
Pathway	REACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5	STAT5A STAT5B	5.92e-04	7	76	2	M27907
Pathway	REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION	STAT5A STAT5B PIK3CA	6.07e-04	31	76	3	M661
Pathway	PID_PDGFRB_PATHWAY	STAT5A STAT5B PIK3CA LRP1 TAGLN	6.52e-04	129	76	5	M186
Pathway	BIOCARTA_GH_PATHWAY	STAT5A STAT5B PIK3CA	7.31e-04	33	76	3	MM1404
Pathway	REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING	STAT5A STAT5B PIK3CA	8.71e-04	35	76	3	MM15144
Pathway	BIOCARTA_IL2RB_PATHWAY	STAT5A STAT5B PIK3CA	9.46e-04	36	76	3	MM1418
Pathway	PID_GMCSF_PATHWAY	STAT5A STAT5B PIK3CA	9.46e-04	36	76	3	M22
Pathway	REACTOME_INTERLEUKIN_9_SIGNALING	STAT5A STAT5B	1.01e-03	9	76	2	M27861
Pathway	BIOCARTA_IL22BP_PATHWAY	STAT5A STAT5B	1.01e-03	9	76	2	MM1419
Pathway	BIOCARTA_IL22BP_PATHWAY	STAT5A STAT5B	1.01e-03	9	76	2	M8066
Pathway	BIOCARTA_IL2RB_PATHWAY	STAT5A STAT5B PIK3CA	1.03e-03	37	76	3	M8615
Pathway	REACTOME_SIGNALING_BY_SCF_KIT	STAT5A STAT5B PIK3CA	1.03e-03	37	76	3	MM14564
Pathway	REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE	STAT5A STAT5B PIK3CA	1.11e-03	38	76	3	M27536
Pathway	REACTOME_FLT3_SIGNALING	STAT5A STAT5B PIK3CA	1.11e-03	38	76	3	M29803
Pathway	PID_ERBB4_PATHWAY	STAT5A STAT5B PIK3CA	1.11e-03	38	76	3	M13
Pathway	REACTOME_INTERLEUKIN_21_SIGNALING	STAT5A STAT5B	1.26e-03	10	76	2	M27898
Pathway	REACTOME_STAT5_ACTIVATION_DOWNSTREAM_OF_FLT3_ITD_MUTANTS	STAT5A STAT5B	1.26e-03	10	76	2	M41731
Pathway	REACTOME_INTERLEUKIN_2_SIGNALING	STAT5A STAT5B	1.26e-03	10	76	2	MM15618
Pathway	REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	STAT5A STAT5B PIK3CA	1.39e-03	41	76	3	MM15162
Pathway	PID_TCPTP_PATHWAY	STAT5A STAT5B PIK3CA	1.49e-03	42	76	3	M91
Pathway	REACTOME_SIGNALING_BY_LEPTIN	STAT5A STAT5B	1.53e-03	11	76	2	M27195
Pathway	REACTOME_INTERLEUKIN_15_SIGNALING	STAT5A STAT5B	1.53e-03	11	76	2	MM15578
Pathway	REACTOME_SIGNALING_BY_SCF_KIT	STAT5A STAT5B PIK3CA	1.59e-03	43	76	3	M508
Pathway	REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING	STAT5A STAT5B PIK3CA	1.70e-03	44	76	3	M1012
Pathway	REACTOME_INTERLEUKIN_2_SIGNALING	STAT5A STAT5B	1.83e-03	12	76	2	M27893
Pathway	WP_RESOLVIN_E1_AND_RESOLVIN_D1_SIGNALING_DECREASE_INFLAMMATION	EPHB2 PIK3CA	1.83e-03	12	76	2	M45559
Pathway	WP_15Q25_COPY_NUMBER_VARIATION	SHANK1 WHAMM RYR1	1.94e-03	46	76	3	M48105
Pathway	WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING	STAT5A STAT5B PIK3CA	2.06e-03	47	76	3	M39380
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	1.04e-09	6	102	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	1.04e-09	6	102	4	25930072
Pubmed	Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.	STAT5A STAT5B NCOR2	2.45e-08	3	102	3	11726519
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SHANK1 CACNB2 ANK3 AAK1 SHANK2 MACF1 GNAS AGAP4 AGAP6	1.53e-07	281	102	9	28706196
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1	7.08e-07	24	102	4	32212159
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 ACTR8 ANK3 POLG KIF1B WHAMM DAZAP2 KRIT1 STAT5B MAPK8IP3 DHX30 LRP1 MACF1 DAAM2 PLEC HECTD1	1.05e-06	1285	102	16	35914814
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF1B AAK1 PFKFB2 UNC45A RFX7 ALMS1 KMT2A MACF1 GNAS PLEC HECTD1 BICC1 DOP1A	1.48e-06	861	102	13	36931259
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNB2 MAN2B2 ANK3 POLG KIF1B AAK1 ATP8B1 STAT5B MAPK8IP3 NCOR2 SHANK2 LRP1 MACF1 GNAS HECTD1 GNL3 DOP1A	1.52e-06	1489	102	17	28611215
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	ANK3 KIF1B DHX30 SHANK2 MACF1 DOP1A	2.23e-06	128	102	6	30995482
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	LAMA1 PFKM RYR1 KMT2A DNAH5 DOP1A NLRP5	2.82e-06	208	102	7	33230847
Pubmed	Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.	EPHB2 STAT5A STAT5B	2.90e-06	10	102	3	18694996
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DHX40 LAMA1 DHX30 MACF1 PLEC DNAH5 GNL3	6.12e-06	234	102	7	36243803
Pubmed	Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.	STAT5A STAT5B	8.52e-06	2	102	2	23151802
Pubmed	Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.	STAT5A STAT5B	8.52e-06	2	102	2	26999798
Pubmed	A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.	STAT5A STAT5B	8.52e-06	2	102	2	31443474
Pubmed	Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.	STAT5A STAT5B	8.52e-06	2	102	2	12377952
Pubmed	A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.	STAT5A STAT5B	8.52e-06	2	102	2	21127177
Pubmed	The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.	STAT5A STAT5B	8.52e-06	2	102	2	16289657
Pubmed	Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.	STAT5A STAT5B	8.52e-06	2	102	2	25552366
Pubmed	Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.	STAT5A STAT5B	8.52e-06	2	102	2	25470773
Pubmed	Constitutively active Stat5A and Stat5B promote adipogenesis.	STAT5A STAT5B	8.52e-06	2	102	2	21431790
Pubmed	Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.	STAT5A STAT5B	8.52e-06	2	102	2	28500076
Pubmed	STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.	STAT5A STAT5B	8.52e-06	2	102	2	21826656
Pubmed	Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.	STAT5A STAT5B	8.52e-06	2	102	2	7720707
Pubmed	STAT5A and STAT5B have opposite correlations with drug response gene expression.	STAT5A STAT5B	8.52e-06	2	102	2	27264955
Pubmed	Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.	STAT5A STAT5B	8.52e-06	2	102	2	22159083
Pubmed	STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.	STAT5A STAT5B	8.52e-06	2	102	2	20008792
Pubmed	STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.	STAT5A STAT5B	8.52e-06	2	102	2	33199496
Pubmed	The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.	STAT5A STAT5B	8.52e-06	2	102	2	16502315
Pubmed	Stat5: an essential regulator of mast cell biology.	STAT5A STAT5B	8.52e-06	2	102	2	12217382
Pubmed	Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.	STAT5A STAT5B	8.52e-06	2	102	2	31599926
Pubmed	DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.	STAT5A STAT5B	8.52e-06	2	102	2	10594041
Pubmed	Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.	STAT5A STAT5B	8.52e-06	2	102	2	21036145
Pubmed	Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.	STAT5A STAT5B	8.52e-06	2	102	2	10486277
Pubmed	Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.	STAT5A STAT5B	8.52e-06	2	102	2	16840779
Pubmed	The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.	STAT5A STAT5B	8.52e-06	2	102	2	15128421
Pubmed	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.	STAT5A STAT5B	8.52e-06	2	102	2	30377054
Pubmed	Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.	STAT5A STAT5B	8.52e-06	2	102	2	23565285
Pubmed	Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.	STAT5A STAT5B	8.52e-06	2	102	2	32790723
Pubmed	In vivo identification of novel STAT5 target genes.	STAT5A STAT5B	8.52e-06	2	102	2	18492722
Pubmed	Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.	STAT5A STAT5B	8.52e-06	2	102	2	10066807
Pubmed	Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.	STAT5A STAT5B	8.52e-06	2	102	2	10835485
Pubmed	A new mouse model for autosomal recessive polycystic kidney disease.	ANK3 BICC1	8.52e-06	2	102	2	11944981
Pubmed	Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.	STAT5A STAT5B	8.52e-06	2	102	2	35464049
Pubmed	Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.	STAT5A STAT5B	8.52e-06	2	102	2	18286195
Pubmed	Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.	STAT5A STAT5B	8.52e-06	2	102	2	23773921
Pubmed	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.	STAT5A STAT5B	8.52e-06	2	102	2	8631883
Pubmed	Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.	STAT5A STAT5B	8.52e-06	2	102	2	11030348
Pubmed	Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.	STAT5A STAT5B	8.52e-06	2	102	2	24878107
Pubmed	Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.	STAT5A STAT5B	8.52e-06	2	102	2	12847485
Pubmed	Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.	STAT5A STAT5B	8.52e-06	2	102	2	12835478
Pubmed	Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.	STAT5A STAT5B	8.52e-06	2	102	2	7568026
Pubmed	Identification of STAT5A and STAT5B target genes in human T cells.	STAT5A STAT5B	8.52e-06	2	102	2	24497979
Pubmed	Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.	STAT5A STAT5B	8.52e-06	2	102	2	17536022
Pubmed	STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.	STAT5A STAT5B	8.52e-06	2	102	2	17382296
Pubmed	STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.	STAT5A STAT5B	8.52e-06	2	102	2	17911616
Pubmed	STAT5 signaling in sexually dimorphic gene expression and growth patterns.	STAT5A STAT5B	8.52e-06	2	102	2	10486314
Pubmed	The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.	STAT5A STAT5B	8.52e-06	2	102	2	17599554
Pubmed	MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.	STAT5A STAT5B	8.52e-06	2	102	2	24497923
Pubmed	Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.	STAT5A STAT5B	8.52e-06	2	102	2	24335105
Pubmed	Brain STAT5 signaling modulates learning and memory formation.	STAT5A STAT5B	8.52e-06	2	102	2	29460051
Pubmed	The Stat5-RARalpha fusion protein represses transcription and differentiation through interaction with a corepressor complex.	STAT5B NCOR2	8.52e-06	2	102	2	11929749
Pubmed	STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.	STAT5A STAT5B	8.52e-06	2	102	2	28606561
Pubmed	Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.	STAT5A STAT5B	8.52e-06	2	102	2	12393407
Pubmed	The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.	STAT5A STAT5B	8.52e-06	2	102	2	12039059
Pubmed	Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.	STAT5A STAT5B	8.52e-06	2	102	2	21178171
Pubmed	Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.	STAT5A STAT5B	8.52e-06	2	102	2	20233708
Pubmed	Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.	STAT5A STAT5B	8.52e-06	2	102	2	16775227
Pubmed	STAT5 isoforms: controversies and clarifications.	STAT5A STAT5B	8.52e-06	2	102	2	17447893
Pubmed	Acidic glycosaminoglycans and laminin-1 in renal corpuscles of mutant blebs (my) and control mice.	LAMA1 FREM2	8.52e-06	2	102	2	9302549
Pubmed	Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.	STAT5A STAT5B	8.52e-06	2	102	2	16115927
Pubmed	Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.	STAT5A STAT5B	8.52e-06	2	102	2	23275557
Pubmed	Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation.	STAT5A STAT5B	8.52e-06	2	102	2	11867689
Pubmed	Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.	STAT5A STAT5B	8.52e-06	2	102	2	15980098
Pubmed	Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.	STAT5A STAT5B	8.52e-06	2	102	2	15340066
Pubmed	STAT5A/B gene locus undergoes amplification during human prostate cancer progression.	STAT5A STAT5B	8.52e-06	2	102	2	23660011
Pubmed	Role of Stat5 in type I interferon-signaling and transcriptional regulation.	STAT5A STAT5B	8.52e-06	2	102	2	12901872
Pubmed	O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.	STAT5A STAT5B	8.52e-06	2	102	2	28074064
Pubmed	STAT5b: A master regulator of key biological pathways.	STAT5A STAT5B	8.52e-06	2	102	2	36755813
Pubmed	Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling.	STAT5A STAT5B	8.52e-06	2	102	2	25333863
Pubmed	A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance.	STAT5A STAT5B	8.52e-06	2	102	2	12421978
Pubmed	A single amino acid in the DNA binding regions of STAT5A and STAT5B confers distinct DNA binding specificities.	STAT5A STAT5B	8.52e-06	2	102	2	9852045
Pubmed	Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.	STAT5A STAT5B	8.52e-06	2	102	2	19966185
Pubmed	Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.	STAT5A STAT5B	8.52e-06	2	102	2	21704724
Pubmed	Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.	STAT5A STAT5B	8.52e-06	2	102	2	38618957
Pubmed	Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.	SHANK1 SHANK2	8.52e-06	2	102	2	25188300
Pubmed	Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.	STAT5A STAT5B	8.52e-06	2	102	2	8732682
Pubmed	How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5.	STAT5A STAT5B	8.52e-06	2	102	2	26717567
Pubmed	The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5.	STAT5A STAT5B	8.52e-06	2	102	2	32281944
Pubmed	Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice.	STAT5A STAT5B	8.52e-06	2	102	2	34818373
Pubmed	Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting.	STAT5A STAT5B	8.52e-06	2	102	2	23465551
Pubmed	STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells.	STAT5A STAT5B	8.52e-06	2	102	2	11756158
Pubmed	IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice.	STAT5A STAT5B	8.52e-06	2	102	2	29203513
Pubmed	WDR87 interacts with CFAP47 protein in the middle piece of spermatozoa flagella to participate in sperm tail assembly.	CFAP47 WDR87	8.52e-06	2	102	2	36571501
Pubmed	Prognostic significance of signal transducer and activator of transcription 5 and 5b expression in Epstein-Barr virus-positive patients with chronic lymphocytic leukemia.	STAT5A STAT5B	8.52e-06	2	102	2	27367207
Pubmed	Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.	STAT5A STAT5B	8.52e-06	2	102	2	16493008
Pubmed	Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.	STAT5A STAT5B	8.52e-06	2	102	2	8816482
Pubmed	The role of STAT proteins in growth hormone signaling.	STAT5A STAT5B	8.52e-06	2	102	2	10851057
Pubmed	Genome-wide regulation of electro-acupuncture on the neural Stat5-loss-induced obese mice.	STAT5A STAT5B	8.52e-06	2	102	2	28806763
Pubmed	Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.	STAT5A STAT5B	8.52e-06	2	102	2	29105654
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	1.36e-04	8	102	2	chr9q12
GeneFamily	Ankyrin repeat domain containing	SHANK1 ANK3 KRIT1 SHANK2 HECTD1 AGAP4 AGAP6	4.96e-05	242	72	7	403
GeneFamily	Sterile alpha motif domain containing	EPHB2 SHANK1 SHANK2 BICC1	4.19e-04	88	72	4	760
GeneFamily	EF-hand domain containing\|Plakins	MACF1 PLEC	4.31e-04	8	72	2	939
GeneFamily	DEAH-box helicases	DHX40 DHX30	1.81e-03	16	72	2	500
GeneFamily	Dyneins, axonemal	DNAH5 DNAH8	2.05e-03	17	72	2	536
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6	2.05e-03	17	72	2	1291
GeneFamily	DNA polymerases	POLG REV1	3.75e-03	23	72	2	535
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MPP2 CACNB2	4.78e-03	26	72	2	904
Coexpression	GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP	AAK1 DAZAP2 ALMS1 PIK3CA KMT2A MACF1 ASXL2	1.23e-05	199	101	7	M7596
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_UP	KIF1B ACOT7 DAZAP2 OAS3 UNC45A KMT2A REV1	1.27e-05	200	101	7	M4016
Coexpression	JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN	ACOT7 PFKM LRP1 GNAS	2.28e-05	43	101	4	M1240
Coexpression	JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN	ACOT7 PFKM LRP1 GNAS	3.55e-05	48	101	4	MM529
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHANK1 CACNB2 SGCZ LRP1 DAAM2 KCNK17 GPR176 BICC1	1.02e-08	183	102	8	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 ANK3 SGCZ LRP1 DAAM2 TAGLN GPR176	2.36e-07	185	102	7	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DYNLRB2 MACF1 DNAH5 HYDIN	3.48e-07	196	102	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DYNLRB2 MACF1 DNAH5 HYDIN	3.48e-07	196	102	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 SHANK2 DYNLRB2 DNAH5 HYDIN	2.24e-06	165	102	6	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 SHANK2 DYNLRB2 DNAH5 HYDIN	2.24e-06	165	102	6	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SGCZ LRP1 DAAM2 TAGLN BICC1	3.58e-06	179	102	6	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SGCZ DAAM2 TAGLN GPR176 BICC1	4.06e-06	183	102	6	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 ANK3 SGCZ DAAM2 TAGLN GPR176	4.33e-06	185	102	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 SGCZ LRP1 DAAM2 GPR176 BICC1	4.89e-06	189	102	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 LAMA1 FREM2 SHANK2 HYDIN BICC1	5.68e-06	194	102	6	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DYNLRB2 DNAH5 HYDIN	5.85e-06	195	102	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 LAMA1 FREM2 SHANK2 HYDIN BICC1	6.02e-06	196	102	6	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DYNLRB2 DNAH5 HYDIN	6.02e-06	196	102	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADGRG3 KIF1B PFKFB2 CR1 STAT5B HPGD	6.76e-06	200	102	6	6beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	SETD1A ANK3 KIF1B SHANK2 KMT2A KIF3C	6.76e-06	200	102	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADGRG3 KIF1B PFKFB2 CR1 STAT5B HPGD	6.76e-06	200	102	6	026495aa7f1e7528a01d9199475cfc393677fc60
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 SHANK2 DYNLRB2 DNAH5 HYDIN	2.55e-05	151	102	5	8216462e723fec2797387929dde095370947e10a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA1 SHANK2 DNAH5 HYDIN BICC1	3.79e-05	164	102	5	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 ATAD5 RHAG DYNLRB2 NLRP5	4.50e-05	170	102	5	4ab2a890c8631028ee9099d2faf6091c742a317b
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	CFAP47 STAT5A ENO4 DYNLRB2 DNAH5	4.63e-05	171	102	5	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	droplet-Fat-Gat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 DYNLRB2 DNAH5 HYDIN CCDC158	4.89e-05	173	102	5	f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCell	droplet-Fat-Gat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 DYNLRB2 DNAH5 HYDIN CCDC158	4.89e-05	173	102	5	a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCell	droplet-Fat-Gat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 DYNLRB2 DNAH5 HYDIN CCDC158	4.89e-05	173	102	5	f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 ENO4 DYNLRB2 HYDIN CCDC158	5.45e-05	177	102	5	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 ENO4 DYNLRB2 DNAH5 HYDIN	5.45e-05	177	102	5	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 ENO4 DYNLRB2 DNAH5 HYDIN	5.45e-05	177	102	5	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 ENO4 DYNLRB2 HYDIN CCDC158	5.60e-05	178	102	5	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 ENO4 DYNLRB2 HYDIN CCDC158	5.60e-05	178	102	5	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 DYNLRB2 DNAH5 HYDIN CCDC158	6.06e-05	181	102	5	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 DYNLRB2 DNAH5 HYDIN CCDC158	6.06e-05	181	102	5	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 DYNLRB2 DNAH5 HYDIN CCDC158	6.06e-05	181	102	5	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 FREM2 LOXHD1 DNAH5 HYDIN	6.55e-05	184	102	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 FREM2 LOXHD1 DNAH5 HYDIN	6.55e-05	184	102	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 FREM2 LOXHD1 DNAH5 HYDIN	6.55e-05	184	102	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 FREM2 DYNLRB2 DNAH5 HYDIN	6.72e-05	185	102	5	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 SHANK2 DNAH5 HYDIN TCTN2	6.72e-05	185	102	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VSIG10 ENO4 DYNLRB2 DNAH5 HYDIN	6.89e-05	186	102	5	29c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 PFKFB2 FREM2 SHANK2 FMN1	7.07e-05	187	102	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 ANK3 FREM2 TAGLN BICC1	7.25e-05	188	102	5	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 CYP39A1 LRP1 TAGLN BICC1	7.43e-05	189	102	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 SHANK2 DYNLRB2 DNAH5 HYDIN	7.62e-05	190	102	5	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 SHANK2 DYNLRB2 DNAH5 HYDIN	7.62e-05	190	102	5	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 CYP39A1 LRP1 TAGLN BICC1	7.62e-05	190	102	5	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 LAMA1 DNAH5 HYDIN BICC1	7.81e-05	191	102	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 ATP8B1 FREM2 SHANK2 DNAH5	7.81e-05	191	102	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 CYP39A1 LRP1 TAGLN BICC1	8.00e-05	192	102	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	ANK3 SHANK2 DYNLRB2 DNAH5 HYDIN	8.00e-05	192	102	5	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 PFKFB2 VSIG10 FREM2 SHANK2	8.00e-05	192	102	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 CYP39A1 LRP1 TAGLN BICC1	8.00e-05	192	102	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 LRP1 DAAM2 TAGLN BICC1	8.00e-05	192	102	5	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	CFAP47 SHANK2 DYNLRB2 DNAH5 HYDIN	8.00e-05	192	102	5	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 DYNLRB2 DNAH5 HYDIN BICC1	8.20e-05	193	102	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 PFKFB2 FREM2 DNAH5 HYDIN	8.20e-05	193	102	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 SHANK2 DYNLRB2 DNAH5 HYDIN	8.40e-05	194	102	5	958e648138676d46698090b4046cb484083ae449
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DNAH5 HYDIN	8.61e-05	195	102	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 ANK3 SHANK2 DNAH5 HYDIN	8.61e-05	195	102	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1B PFKFB2 SGCZ KMT2A MACF1	8.61e-05	195	102	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1B PFKFB2 SGCZ KMT2A MACF1	8.61e-05	195	102	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADGRG3 AAK1 CR1 HPGD MACF1	8.82e-05	196	102	5	5bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCell	primary_visual_cortex-Neuronal\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SHANK1 ANK3 AAK1 ACOT7 ATP6V1H	8.82e-05	196	102	5	8efc2b3a95f57c31be203ac781b2098d4909297f
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SHANK1 ANK3 AAK1 ACOT7 ATP6V1H	8.82e-05	196	102	5	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 LAMA1 FREM2 SHANK2 BICC1	8.82e-05	196	102	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ANK3 SHANK2 HYDIN BICC1	9.03e-05	197	102	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 DYNLRB2 DNAH5 HYDIN CCDC158	9.03e-05	197	102	5	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 AAK1 ZNF407 DDHD1 MACF1	9.47e-05	199	102	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADGRG3 KIF1B PFKFB2 CR1 STAT5B	9.47e-05	199	102	5	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 WHAMM RASGRP1 KMT2A MACF1	9.47e-05	199	102	5	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	OAS3 CR1 NCAPG2 AGAP6 DOP1A	9.47e-05	199	102	5	c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CACNB2 WDR36 LRP1 TAGLN BICC1	9.47e-05	199	102	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ADGRG3 KIF1B PFKFB2 CR1 STAT5B	9.69e-05	200	102	5	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	CACNB2 LAMA1 LRP1 MACF1 BICC1	9.69e-05	200	102	5	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	OAS3 KMT2A MACF1 GNAS RAD21	9.69e-05	200	102	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	CR1 LRP1 MACF1 GNAS PLEC	9.69e-05	200	102	5	a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell	severe-CD163+_Monocytes_(Sample_ID1_d7)\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EPHB2 OTUD1 OAS3 CR1 LRP1	9.69e-05	200	102	5	a3f22826f3d8f917ff0594bdadd93b60763bcaa2
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	ENO4 HPGD DYNLRB2 DNAH5 HYDIN	9.69e-05	200	102	5	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 ATP8B1 SHANK2 FMN1 RAVER2	9.69e-05	200	102	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AAK1 HPGD AGAP4 AGAP6	1.07e-04	107	102	4	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AAK1 HPGD AGAP4 AGAP6	1.07e-04	107	102	4	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	Control-CD4+_T_activated\|Control / Disease condition and Cell class	OAS3 LMOD2 SHANK2 DNAH5	1.47e-04	116	102	4	e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	OAS3 LMOD2 SHANK2 DNAH5	1.57e-04	118	102	4	f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OAS3 LMOD2 SHANK2 DNAH5	1.57e-04	118	102	4	0dcac16eea8e7978de370a815da9a0cdd212598e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OAS3 LMOD2 SHANK2 DNAH5	1.57e-04	118	102	4	7da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OAS3 LMOD2 SHANK2 DNAH5	1.57e-04	118	102	4	c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCell	Control-Lymphoid_T/NK-CD4+_T_activated\|Control / Disease group, lineage and cell class	OAS3 LMOD2 SHANK2 DNAH5	1.62e-04	119	102	4	d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	POLG AAK1 LRP1 NIN	1.78e-04	122	102	4	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	368C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 OAS3 STAT5A DAAM2	2.93e-04	139	102	4	39f3c28f89c37bb8cc049c56d2948ea906fb3d86
ToppCell	368C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 OAS3 STAT5A DAAM2	2.93e-04	139	102	4	4efab4421e3448880a1dcf981f6a65131b038010
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SHANK1 TAGLN KCNK17 CCDC158	3.18e-04	142	102	4	61eefa32926a057e53747633bf4a81f09ea721c5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-OPC_related\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RASGRP1 PLEC PCBP4 PRIMPOL	3.18e-04	142	102	4	d2d150e3019a5b7b143e50b1c1c2b6764abf36bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-OPC_related-Oligodendrocyte/OPC\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RASGRP1 PLEC PCBP4 PRIMPOL	3.18e-04	142	102	4	43e72e4b9ae33768672ef90c8bbfd2ca1818c746
ToppCell	Healthy_donor-B_cell\|World / disease group, cell group and cell class (v2)	ATP8B1 KCNK17 DNAH8 PRIMPOL	3.91e-04	150	102	4	a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR1 RASGRP1 HPGD LRP1	4.11e-04	152	102	4	82a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	ADGRG3 ANK3 STAT5B CCDC158	4.11e-04	152	102	4	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP39A1 ALMS1 DNAH5 HYDIN	4.32e-04	154	102	4	ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	CACNB2 RYR1 RASGRP1 DNAH8	4.43e-04	155	102	4	d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	SHANK1 PFKFB2 KCNK17 BICC1	4.65e-04	157	102	4	eb2520c237543ea4869d4386afc0457b111f6193
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC4F HPGD RAVER2 LRP1	4.76e-04	158	102	4	d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCell	Control-Lymphocyte-T_NK-Treg\|Control / Disease, Lineage and Cell Type	AAK1 RASGRP1 HPGD DNAH8	4.76e-04	158	102	4	260dc209f619e1d17a11cede979636001c749786
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 DAAM2 PCBP4 DNAH5	4.76e-04	158	102	4	f296ca24fdedc33f1d24b79e7660763114ce7fa3
Drug	Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A	EPHB2 CACNB2 ACTR8 ANK3 POLG ZNF407 PFKFB2 UNC45A NCOR2	2.09e-07	198	99	9	3134_UP
Drug	Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	SETD1A ACTR8 POLG ZNF813 STAT5B SHANK2 ABCD4 MACF1	2.12e-06	194	99	8	7468_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A	ANK3 ATAD5 POLG AAK1 CYP39A1 NCOR2 LRP1 BICC1	2.21e-06	195	99	8	1214_UP
Drug	Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; PC3; HG-U133A	ANK3 ACOT7 MAPK8IP3 KIF3C GNAS PLEC GPR176 RAD21	2.29e-06	196	99	8	1927_DN
Drug	Nadolol [42200-33-9]; Down 200; 13uM; HL60; HT_HG-U133A	EPHB2 CACNB2 ACTR8 ANK3 ZNF407 KIF3C PLEC TAGLN	2.66e-06	200	99	8	3020_DN
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A	EPHB2 SETD1A CACNB2 ATAD5 NCOR2 KMT2A GPR176	1.97e-05	190	99	7	3848_UP
Drug	diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A	ANK3 POLG PIP5K1C NCOR2 KMT2A PLEC DOP1A	2.32e-05	195	99	7	333_DN
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; HL60; HG-U133A	ACTR8 UNC45A RHAG STAT5B KMT2A DOP1A TCTN2	2.32e-05	195	99	7	1366_DN
Drug	Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; PC3; HT_HG-U133A	EPHB2 ATAD5 CYP39A1 MAPK8IP3 SHANK2 LRP1 GPR176	2.40e-05	196	99	7	7300_UP
Drug	Pentoxifylline [6493-05-6]; Down 200; 14.4uM; HL60; HG-U133A	AAK1 ATP8B1 KRIT1 MAPK8IP3 ALMS1 KMT2A RAD21	2.40e-05	196	99	7	1444_DN
Drug	sulindac; Down 200; 100uM; MCF7; HG-U133A	ATAD5 AAK1 MAPK8IP3 NCOR2 ABCD4 KMT2A KIF3C	2.48e-05	197	99	7	168_DN
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A	EPHB2 CACNB2 ANK3 STAT5A KIF3C GNAS PCBP4	2.48e-05	197	99	7	3019_DN
Drug	Penbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A	AAK1 DAZAP2 STAT5B NCOR2 SHANK2 KMT2A GNAS	2.48e-05	197	99	7	7476_UP
Drug	C75; Down 200; 10uM; PC3; HT_HG-U133A	EPHB2 ACTR8 DAZAP2 UNC45A MAPK8IP3 PCBP4 BICC1	2.48e-05	197	99	7	6428_DN
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A	SETD1A UNC45A MAPK8IP3 SHANK2 HPGD KIF3C PLEC	2.56e-05	198	99	7	6508_DN
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; HL60; HT_HG-U133A	ATAD5 UNC45A KRIT1 STAT5B MAPK8IP3 ABCD4 KIF3C	2.56e-05	198	99	7	1838_DN
Drug	Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A	EPHB2 CACNB2 MAPK8IP3 NCOR2 ALMS1 HPGD GNAS	2.56e-05	198	99	7	4812_UP
Drug	alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A	SETD1A PIP5K1C STAT5A STAT5B NCOR2 TAGLN PCBP4	2.73e-05	200	99	7	2670_DN
Drug	Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; PC3; HT_HG-U133A	EPHB2 DAZAP2 PFKFB2 KRIT1 MAPK8IP3 ALMS1 DOP1A	2.73e-05	200	99	7	4475_DN
Drug	AZD 1480	STAT5A STAT5B	1.12e-04	4	99	2	ctd:C545606
Drug	UM-272	PFKM KRIT1	1.12e-04	4	99	2	CID000038088
Drug	N-methyl-DL-aspartic acid	EPHB2 SHANK1 CACNB2 PFKM RYR1 KRIT1 SHANK2 PIK3CA LRP1 GNAS GNL3	1.31e-04	655	99	11	CID000004376
Drug	geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A	ACTR8 UNC45A STAT5B MAPK8IP3 KIF3C TCTN2	1.33e-04	179	99	6	1169_UP
Drug	Corticosterone [50-22-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A	MPP2 ATP8B1 UNC45A PIP5K1C MAPK8IP3 RASGRP1	1.69e-04	187	99	6	3244_DN
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MPP2 ANK3 ATAD5 KRIT1 STAT5B MACF1	1.74e-04	188	99	6	6451_DN
Drug	Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ANK3 ATAD5 KRIT1 ALMS1 MACF1 TAGLN	1.89e-04	191	99	6	4811_DN
Drug	Paclitaxel [33069-62-4]; Down 200; 4.6uM; PC3; HT_HG-U133A	EPHB2 PFKFB2 MACF1 GNAS PLEC GPR176	1.89e-04	191	99	6	6720_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A	EPHB2 SHANK1 NCOR2 ALMS1 DAAM2 GPR176	1.95e-04	192	99	6	2831_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	SETD1A ZNF813 ZNF407 KRIT1 KIF3C PLEC	2.00e-04	193	99	6	3077_DN
Drug	ikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA	MPP2 ACTR8 POLG ZNF813 ALMS1 TAGLN	2.00e-04	193	99	6	866_DN
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	ATAD5 AAK1 UNC45A KRIT1 STAT5B PLEC	2.00e-04	193	99	6	4846_DN
Drug	Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA	EPHB2 SETD1A CR1 NCOR2 SHANK2 TCTN2	2.00e-04	193	99	6	948_UP
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A	EPHB2 CACNB2 ANK3 UNC45A HPGD TAGLN	2.12e-04	195	99	6	3124_UP
Drug	Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; HL60; HG-U133A	ATP8B1 KRIT1 MAPK8IP3 MACF1 TCTN2 RAD21	2.12e-04	195	99	6	1431_DN
Drug	Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A	EPHB2 SETD1A PFKFB2 RHAG MAPK8IP3 RAVER2	2.12e-04	195	99	6	2875_UP
Drug	Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ATAD5 POLG VSIG10 PIP5K1C STAT5B ALMS1	2.17e-04	196	99	6	7022_DN
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; HL60; HT_HG-U133A	MPP2 AAK1 UNC45A VSIG10 CR1 DOP1A	2.17e-04	196	99	6	2198_DN
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A	EPHB2 ATAD5 ZNF407 NCOR2 BICC1 DOP1A	2.17e-04	196	99	6	4551_UP
Drug	Carisoprodol [78-44-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	MPP2 ATP8B1 PFKFB2 PIP5K1C CYP39A1 LRP1	2.17e-04	196	99	6	6610_DN
Drug	Betonicine [515-25-3]; Up 200; 25.2uM; HL60; HT_HG-U133A	MPP2 ANK3 UNC45A RHAG SHANK2 PLEC	2.17e-04	196	99	6	2207_UP
Drug	Ofloxacin [82419-36-1]; Down 200; 11uM; PC3; HT_HG-U133A	EPHB2 SETD1A ATAD5 ACOT7 NCOR2 GPR176	2.17e-04	196	99	6	3673_DN
Drug	Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A	EPHB2 MPP2 SETD1A CACNB2 POLG UNC45A	2.23e-04	197	99	6	3572_DN
Drug	Hydroflumethiazide [135-09-1]; Up 200; 12uM; PC3; HT_HG-U133A	EPHB2 DAZAP2 UNC45A RYR1 KRIT1 NCOR2	2.23e-04	197	99	6	7259_UP
Drug	ICI 182,780; Down 200; 1uM; PC3; HG-U133A	MPP2 POLG AAK1 ATP8B1 RHAG ALMS1	2.23e-04	197	99	6	704_DN
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; HL60; HG-U133A	ATP8B1 UNC45A CR1 RHAG KIF3C TCTN2	2.23e-04	197	99	6	1713_DN
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A	EPHB2 ATP8B1 MAPK8IP3 NCOR2 LRP1 KIF3C	2.23e-04	197	99	6	6621_DN
Drug	chlorpropamide; Up 200; 100uM; MCF7; HG-U133A	EPHB2 ADGRG3 ANK3 CR1 PLEC BICC1	2.23e-04	197	99	6	141_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; HL60; HT_HG-U133A	KIF1B PFKFB2 STAT5B LRP1 DAAM2 KIF3C	2.23e-04	197	99	6	2356_UP
Drug	bepridil	CACNB2 LAMTOR5 RYR1 KRIT1 SHANK2	2.26e-04	126	99	5	CID000002351
Drug	Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	CACNB2 AAK1 OAS3 PFKFB2 RHAG RYR1	2.30e-04	198	99	6	2841_UP
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A	SETD1A ZNF407 PIP5K1C MAPK8IP3 NCOR2 DOP1A	2.30e-04	198	99	6	4762_DN
Drug	Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A	SHANK1 SETD1A ATP8B1 ALMS1 GNAS GPR176	2.30e-04	198	99	6	1493_UP
Drug	Trichlorfon [52-68-6]; Down 200; 15.6uM; HL60; HT_HG-U133A	ATAD5 ACOT7 OAS3 UNC45A STAT5B DHX30	2.30e-04	198	99	6	1839_DN
Drug	Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; HL60; HT_HG-U133A	EPHB2 ADGRG3 ANK3 HPGD KIF3C PCBP4	2.30e-04	198	99	6	3128_UP
Drug	Diprophylline [479-18-5]; Down 200; 15.8uM; HL60; HT_HG-U133A	POLG UNC45A PIP5K1C KRIT1 MAPK8IP3 ALMS1	2.30e-04	198	99	6	1853_DN
Drug	Ald1.1-H_000455; Down 200; 10uM; MCF7; HT_HG-U133A	PFKFB2 RFX7 MACF1 KIF3C DOP1A TCTN2	2.30e-04	198	99	6	7516_DN
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT_HG-U133A	AAK1 ZNF407 MAPK8IP3 NCOR2 ABCD4 LRP1	2.30e-04	198	99	6	4214_UP
Drug	Betazole hydrochloride; Down 200; 27uM; PC3; HT_HG-U133A	EPHB2 ANK3 POLG MAPK8IP3 PLEC GPR176	2.30e-04	198	99	6	1812_DN
Drug	Benzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A	EPHB2 ANK3 UNC45A KIF3C PCBP4 TCTN2	2.30e-04	198	99	6	2989_DN
Drug	Alfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A	EPHB2 CACNB2 ZNF407 OAS3 RHAG NCOR2	2.30e-04	198	99	6	3135_UP
Drug	Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; PC3; HG-U133A	POLG OAS3 KRIT1 SHANK2 HPGD GNL3	2.30e-04	198	99	6	1888_DN
Drug	Riluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A	EPHB2 PFKFB2 RHAG STAT5A KIF3C GNAS	2.30e-04	198	99	6	4689_UP
Drug	rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A	CR1 CYP39A1 STAT5A MAPK8IP3 NCOR2 PCBP4	2.36e-04	199	99	6	2693_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; PC3; HT_HG-U133A	ATAD5 POLG ZNF407 PFKFB2 CYP39A1 GPR176	2.36e-04	199	99	6	7281_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A	EPHB2 CACNB2 KRIT1 MAPK8IP3 ALMS1 HPGD	2.36e-04	199	99	6	4826_UP
Drug	Suramin sodium salt; Down 200; 10uM; MCF7; HT_HG-U133A	MPP2 OAS3 RFX7 STAT5B NCOR2 PLEC	2.36e-04	199	99	6	7524_DN
Drug	Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ZNF407 PFKFB2 CR1 STAT5A MAPK8IP3 NCOR2	2.36e-04	199	99	6	2266_UP
Drug	S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; HL60; HT_HG-U133A	EPHB2 SETD1A CR1 STAT5B KMT2A KIF3C	2.36e-04	199	99	6	3082_DN
Drug	Mifepristone [84371-65-3]; Up 200; 9.4uM; HL60; HG-U133A	OAS3 ATP8B1 CR1 STAT5A KRIT1 MACF1	2.36e-04	199	99	6	1569_UP
Drug	Iopromide [73334-07-3]; Up 200; 5uM; HL60; HT_HG-U133A	EPHB2 AAK1 ZNF407 CYP39A1 NCOR2 HPGD	2.36e-04	199	99	6	2739_UP
Drug	Scopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A	ANK3 ZNF407 PFKFB2 CR1 ABCD4 DAAM2	2.42e-04	200	99	6	3131_UP
Drug	Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; HL60; HG-U133A	ACTR8 RFX7 ALMS1 KMT2A MACF1 TCTN2	2.42e-04	200	99	6	1389_DN
Disease	cerebral cavernous malformation (is_implicated_in)	KRIT1 PIK3CA	3.20e-05	3	97	2	DOID:0060669 (is_implicated_in)
Disease	sensory peripheral neuropathy, remission	MPP2 SGCZ KMT2A	5.81e-05	23	97	3	EFO_0009785, MONDO_0002321
Disease	Cerebral cavernous malformation	KRIT1 PIK3CA	6.39e-05	4	97	2	cv:C2919945
Disease	Hereditary cavernous hemangioma of brain	KRIT1 PIK3CA	6.39e-05	4	97	2	cv:C2931263
Disease	colon adenocarcinoma (is_implicated_in)	STAT5A STAT5B PIK3CA	8.48e-05	26	97	3	DOID:234 (is_implicated_in)
Disease	Schizophrenia	SHANK1 SETD1A CACNB2 ANK3 LAMA1 LMOD2 PIK3CA LRP1 KMT2A DAAM2 GNAS	1.55e-04	883	97	11	C0036341
Disease	seasonal allergic rhinitis	WDR36 CLEC4F DNAH5	1.59e-04	32	97	3	EFO_0003956
Disease	Cornelia De Lange Syndrome	KMT2A RAD21	2.96e-04	8	97	2	C0270972
Disease	cerebral palsy (implicated_via_orthology)	AGAP4 AGAP6	4.73e-04	10	97	2	DOID:1969 (implicated_via_orthology)
Disease	Polydactyly	FREM2 ALMS1 PIK3CA TCTN2	6.12e-04	117	97	4	C0152427
Disease	polychlorinated biphenyls measurement, gestational serum measurement	FMN1 BICC1	6.91e-04	12	97	2	EFO_0007042, EFO_0007964
Disease	Fetal Alcohol Spectrum Disorders	ANK3 PIK3CA	8.15e-04	13	97	2	C2985290
Disease	bipolar I disorder	CACNB2 ANK3 SHANK2 PLEC	1.23e-03	141	97	4	EFO_0009963
Disease	triiodothyronine measurement	EPHB2 MPP2	1.25e-03	16	97	2	EFO_0008392
Disease	migraine without aura, susceptibility to, 4	MPP2 LRP1	1.25e-03	16	97	2	MONDO_0011847
Disease	Fetal Alcohol Syndrome	ANK3 PIK3CA	1.41e-03	17	97	2	C0015923
Disease	Nonorganic psychosis	SHANK1 ANK3 LMOD2	1.54e-03	69	97	3	C0349204
Disease	Myeloid Leukemia	KMT2A RAD21	1.58e-03	18	97	2	C0023470
Disease	Leukemia, Monocytic, Chronic	KMT2A RAD21	1.58e-03	18	97	2	C0023466
Disease	hematocrit	KIF1B AAK1 ATP8B1 PFKM CR1 NCOR2 FMN1 ASXL2 HYDIN BICC1	1.82e-03	1011	97	10	EFO_0004348
Disease	Manic	ANK3 SHANK2 DNAH8	2.19e-03	78	97	3	C0338831
Disease	Colorectal Carcinoma	SHANK1 CACNB2 LAMA1 PIK3CA ABCD4 LRP1 GNAS DNAH8	2.22e-03	702	97	8	C0009402
Disease	Carcinoma of lung	PIK3CA RAD21	2.59e-03	23	97	2	C0684249
Disease	Leukemia, Myelocytic, Acute	RASGRP1 KMT2A ASXL2 RAD21	2.59e-03	173	97	4	C0023467
Disease	hepatocellular carcinoma (is_implicated_in)	POLG KIF1B PIK3CA RAD21	3.05e-03	181	97	4	DOID:684 (is_implicated_in)
Disease	descending aortic diameter	UNC45A LRP1 TAGLN	3.09e-03	88	97	3	EFO_0021788

Protein segments in the cluster

Peptide	Gene	Start	Entry
NVAGNVHGGTILKMI	ACOT7	66	O00154
VHIMKKRNGGGSLNN	AGAP4	176	Q96P64
GIQMVSKNGNLQLHT	ATAD5	451	Q96QE3
ERQGNVLVISHQAVM	PFKFB2	381	O60825
IQIMRDLSGHKNIVG	AAK1	91	Q2M2I8
VGQKMTTLQHRSQGD	ACTR8	401	Q9H981
HQLQNFNTLMAVIGG	RASGRP1	286	O95267
HMLNKGIQAGNLEIV	ALMS1	3881	Q8TCU4
VLNNRLVGLSVGQMH	ADGRG3	176	Q86Y34
HVKVTAQDLIGNRNM	DOP1A	1471	Q5JWR5
GQQLGMTFISVGHRQ	ABCD4	566	O14678
IKGVQQRLQEALGMH	DHX30	681	Q7L2E3
GRNGSNIKHIMQRTG	BICC1	301	Q9H694
IQAAQKQMAHAVRGK	ASXL2	1266	Q76L83
NDVNMIKTAHIGVGI	ATP8B1	896	O43520
RGKSQAKHLNVQMVA	CACNB2	411	Q08289
VHIMKKRNGGGSLNN	AGAP6	176	Q5VW22
IAAQRVMHSNQKGLL	RAVER2	321	Q9HCJ3
QQMLHGLQRALAKTG	RAD21	561	O60216
HILGITMGNQEGKLQ	FMN1	106	Q68DA7
IKALMNNSQGRAHVL	DAAM2	181	Q86T65
QIGAISQGMSVQLHV	NCOR2	1121	Q9Y618
EIRQMSGAHIKIGNQ	PCBP4	266	P57723
QMLNVNIHLTTGGRL	OTUD1	386	Q5VV17
VMQGANVLVTQRKGN	DAZAP2	141	Q15038
IQSHKGVIGTMVVNA	DYNLRB2	11	Q8TF09
VEHIERSKMQQVGGN	MAPK8IP3	176	Q9UPT6
GSQLLEMFHIGQQQI	GPR176	366	Q14439
VQLRSGNRIIMGKNH	KIF1B	616	O60333
AVQRANKHVGSNMKL	LRP1	2441	Q07954
RRVQGAKGFQHQRMT	LRP1	4446	Q07954
QHVTLIVFGIGMVNR	KIAA1109	2771	Q2LD37
GHIMNQLINGTVLVE	FREM2	1236	Q5SZK8
IIEKIRIGHNNTGMN	LOXHD1	1166	Q8IVV2
TGKGILAIMRALQHN	LMOD2	281	Q6P5Q4
IEHVMNLGNQTRAVG	KIF3C	191	O14782
AGHQKKILNSIQVMR	EPHB2	961	P29323
VVLNRLGHLMQQGVN	KCNK17	146	Q96T54
IFDSRKNVLGHMQQG	PFKM	651	P08237
GQGQEVHARKLIQMS	DNAH8	3941	Q96JB1
IQMLSRGLHEQIFGQ	POLG	76	P54098
LKHGNNTTVQQIMEG	KRIT1	436	O00522
IGEHQKTQGLRAIMN	NLRP5	446	P59047
LVIARILHGGMVAQQ	MPP2	186	Q14168
VRNSHTIMQIQCKGG	PIK3CA	851	P42336
NMVRIIASHQVLNGG	MACF1	2721	Q9UPN3
RHVRIKQMGKNASGQ	HECTD1	1211	Q9ULT8
VGRMRGIIHLSVINN	HYDIN	3581	Q4G0P3
VNGMVHVIKGIQFGS	CR1	111	P17927
IVKQMRILHVNGFNG	GNAS	56	P63092
LVNQGAHVDAQTKMG	ANK3	716	Q12955
ISSQGNGQVEVMLHR	MAN2B2	781	Q9Y2E5
NGNIMIQKHDGITVA	LAMTOR5	71	O43504
KRGQQQITGKMSHLG	ENO4	346	A6NNW6
TVLAQRRGMHQKGGI	GNL3	366	Q9BVP2
GSLKNVHMAVIRGKQ	KMT2A	1916	Q03164
KMGTVNLHQFTGQLT	CYP39A1	126	Q9NYL5
VVHGIGQKMDQGRII	DDHD1	411	Q8NEL9
IMKVVQQIVHQASAG	E4F1	671	Q66K89
IENMTQLVGQHGRTA	CCDC158	571	Q5M9N0
SQHGMIGVTQPRKVA	DHX40	96	Q8IX18
VTHNGKQLVMTVGLL	RYR1	4831	P21817
MNTQKGSLTINVHRG	CFAP47	1	Q6ZTR5
QHTFLMNGLIQGVKG	MFSD14C	76	Q5VZR4
QHTFLMNGLIQGVKG	MFSD14B	76	Q5SR56
VHARKLLQQTMANGG	DNAH5	4081	Q8TE73
NIGRAHKSNNIMILV	PRIMPOL	421	Q96LW4
MAQGFRTVLGLVQQH	OAS3	651	Q9Y6K5
LHGQVMDQKLSGQRA	PLA2G4D	436	Q86XP0
MHVNGKVALVTGAAQ	HPGD	1	P15428
RVIEQLGGKQLVMNH	ATP6V1H	426	Q9UI12
SIAGQQHQTRIKMGN	FER1L5	191	A0AVI2
QEVMSLHKQLQNAGG	NIN	1801	Q8N4C6
QADIRHILNKNGGVM	TACO1	161	Q9BSH4
VQSGGKNIRVVVMNN	PIP5K1C	226	O60331
LGGRHQVSINNTAVM	LAMA1	546	P25391
IENILKAHMGRNLGQ	SPATA31A7	726	Q8IWB4
TVRLLVGGKLNVHMN	STAT5B	351	P51692
LRQVIQGHGKANTMV	WHAMM	201	Q8TF30
VTVNARNHMGQLTGQ	SGCZ	111	Q96LD1
SQLQEGKHVIGLQMG	TAGLN	166	Q01995
THGNRQMTVIRKVEG	MRPL49	101	Q13405
MGNIIHAQLDIKGQQ	SETD1A	161	O15047
VVNMIRQGGNHLVLK	SHANK2	701	Q9UPX8
VKVGHRQVVNMIRQG	SHANK1	731	Q9Y566
TVRLLVGGKLNVHMN	STAT5A	351	P42229
HLGNTNADIQMVKGV	CLEC4F	141	Q8N1N0
IQVLNGHMKNASREI	CLEC4F	376	Q8N1N0
KMIHGTIKNQLQGLQ	NCAPG2	241	Q86XI2
NTGQNTMLINLGRHK	SPG11	2306	Q96JI7
IENILKAHMGRNLGQ	SPATA31A3	726	Q5VYP0
IENILKAHMGRNLGQ	SPATA31A1	726	Q5TZJ5
ISDMRGVGIHVNQLV	REV1	811	Q9UBZ9
IENILKAHMGRNLGQ	SPATA31A5	726	Q5VU36
LSMLGAIQQLQQRGH	UGT1A1	41	P22309
KLNMVHIQNATLAGG	RHAG	266	Q02094
GKVLPLNVQVVTQHM	RFX7	291	Q2KHR2
FQAMQKGLIVREHGI	PLEC	2926	Q15149
QAMQKGLVLRQHGIR	PLEC	3586	Q15149
LHMFQTQGKIGNQVE	ZNF813	151	Q6ZN06
HRVTALVNGNIEQMG	VSIG10	501	Q8N0Z9
QTLAMAGQVARVVHI	ZNF407	1891	Q9C0G0
ETVVRVLMHQGKGQL	WDR87	176	Q6ZQQ6
INAHQKGIMTQRFVV	TCTN2	406	Q96GX1
QELQHRGAVVVLNMV	UNC45A	876	Q9H3U1
VVAIGLMSGQVIIHN	WDR36	261	Q8NI36
RHKMAVVQGQLFAVG	KLHL35	386	Q6PF15