Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	complement component C4b binding	CR1 CR1L MASP2	1.54e-07	3	108	3	GO:0001855
GeneOntologyMolecularFunction	endopeptidase activity	PAPPA2 KLK6 PRSS57 ADAM15 RHBDL1 ADAMTS13 TMPRSS11F ADAM12 PRSS36 ESPL1 MASP2	2.15e-05	430	108	11	GO:0004175
GeneOntologyMolecularFunction	complement binding	CR1 CR1L CR2 MASP2	2.59e-05	32	108	4	GO:0001848
GeneOntologyMolecularFunction	complement component C3b receptor activity	CR1 CR1L	2.90e-05	2	108	2	GO:0004877
GeneOntologyMolecularFunction	complement component C4b receptor activity	CR1 CR1L	2.90e-05	2	108	2	GO:0001861
GeneOntologyMolecularFunction	immune receptor activity	IL12RB1 CRLF1 IL20RA CR1 CR1L CR2 IL22RA1	3.21e-05	165	108	7	GO:0140375
GeneOntologyMolecularFunction	complement receptor activity	CR1 CR1L CR2	5.36e-05	14	108	3	GO:0004875
GeneOntologyMolecularFunction	interleukin-20 binding	IL20RA IL22RA1	8.66e-05	3	108	2	GO:0042015
GeneOntologyMolecularFunction	opsonin binding	CR1 CR1L MASP2	3.25e-04	25	108	3	GO:0001846
GeneOntologyMolecularFunction	serine-type endopeptidase activity	KLK6 PRSS57 RHBDL1 TMPRSS11F PRSS36 MASP2	5.88e-04	190	108	6	GO:0004252
GeneOntologyMolecularFunction	opsonin receptor activity	CR1 CR1L	7.94e-04	8	108	2	GO:0001847
GeneOntologyMolecularFunction	peptidase activity	PAPPA2 KLK6 PRSS57 ADAM15 RHBDL1 ADAMTS13 TMPRSS11F ADAM12 PRSS36 ESPL1 MASP2	8.30e-04	654	108	11	GO:0008233
GeneOntologyMolecularFunction	serine-type peptidase activity	KLK6 PRSS57 RHBDL1 TMPRSS11F PRSS36 MASP2	9.19e-04	207	108	6	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	KLK6 PRSS57 RHBDL1 TMPRSS11F PRSS36 MASP2	1.04e-03	212	108	6	GO:0017171
GeneOntologyMolecularFunction	growth hormone receptor binding	TYK2 SOCS2	1.27e-03	10	108	2	GO:0005131
GeneOntologyMolecularFunction	complement component C3b binding	CR1 CR1L	1.85e-03	12	108	2	GO:0001851
GeneOntologyMolecularFunction	cytokine receptor activity	IL12RB1 CRLF1 IL20RA IL22RA1	1.91e-03	97	108	4	GO:0004896
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CR1 CR1L CR2	7.25e-06	8	106	3	GO:0045959
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	CR1 CR1L CR2	1.54e-05	10	106	3	GO:0030450
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2	2.81e-05	12	106	3	GO:0002924
GeneOntologyBiologicalProcess	female pregnancy	KPNA6 CR1 CR1L HAVCR2 THBD FBN2 HSD11B2 CDH1	4.39e-05	249	106	8	GO:0007565
GeneOntologyBiologicalProcess	negative regulation of complement activation	CR1 CR1L CR2	4.61e-05	14	106	3	GO:0045916
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	CR1 CR1L CR2	7.04e-05	16	106	3	GO:0002713
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	CR1 CR1L CR2	7.04e-05	16	106	3	GO:0002890
GeneOntologyBiologicalProcess	complement activation, classical pathway	CR1 CR1L CR2 MASP2	7.64e-05	44	106	4	GO:0006958
GeneOntologyBiologicalProcess	negative regulation of humoral immune response	CR1 CR1L CR2	1.20e-04	19	106	3	GO:0002921
GeneOntologyBiologicalProcess	multi-organism reproductive process	KPNA6 CR1 CR1L HAVCR2 THBD FBN2 HSD11B2 CDH1	1.27e-04	290	106	8	GO:0044703
GeneOntologyBiologicalProcess	multi-multicellular organism process	KPNA6 CR1 CR1L HAVCR2 THBD FBN2 HSD11B2 CDH1	1.40e-04	294	106	8	GO:0044706
GeneOntologyBiologicalProcess	regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2	1.89e-04	22	106	3	GO:0002923
GeneOntologyBiologicalProcess	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	IL12RB1 CR1 CR1L CR2 TYK2 HAVCR2 EXOSC6	2.13e-04	235	106	7	GO:0002822
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2 MASP2	2.92e-04	62	106	4	GO:0002455
GeneOntologyBiologicalProcess	regulation of adaptive immune response	IL12RB1 CR1 CR1L CR2 TYK2 HAVCR2 EXOSC6	3.26e-04	252	106	7	GO:0002819
GeneOntologyBiologicalProcess	regulation of complement activation	CR1 CR1L CR2	3.53e-04	27	106	3	GO:0030449
GeneOntologyBiologicalProcess	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	CR1 CR1L CR2 HAVCR2	3.72e-04	66	106	4	GO:0002823
GeneOntologyBiologicalProcess	branching involved in salivary gland morphogenesis	LAMA5 ESRP2 CDH1	3.94e-04	28	106	3	GO:0060445
GeneOntologyCellularComponent	interleukin-12 receptor complex	IL12RB1 TYK2	7.91e-05	3	108	2	GO:0042022
GeneOntologyCellularComponent	interleukin-23 receptor complex	IL12RB1 TYK2	1.58e-04	4	108	2	GO:0072536
GeneOntologyCellularComponent	side of membrane	ROBO4 IL12RB1 CRLF1 PKP4 CR1 CR1L CR2 CD163 TYK2 THBD LYPD5 CDH1 ALG1	5.79e-04	875	108	13	GO:0098552
GeneOntologyCellularComponent	cell surface	ROBO4 IL12RB1 CRLF1 ADAM15 NTRK2 ADAMTS13 TMPRSS11F CR1 CR1L CR2 CD163 HAVCR2 THBD CIITA CDH1	5.85e-04	1111	108	15	GO:0009986
Domain	Sushi	PAPPA2 CR1 CR1L CR2 MASP2	1.18e-05	52	107	5	PF00084
Domain	CCP	PAPPA2 CR1 CR1L CR2 MASP2	1.42e-05	54	107	5	SM00032
Domain	SUSHI	PAPPA2 CR1 CR1L CR2 MASP2	1.70e-05	56	107	5	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA2 CR1 CR1L CR2 MASP2	1.86e-05	57	107	5	IPR000436
Domain	Ig-like_fold	PAPPA2 ROBO4 IL12RB1 ADAMTSL1 CRLF1 NTRK2 IL20RA IL22RA1 HAVCR2 LRIG3 VSIG10L ADGRF3 MYBPHL	1.98e-04	706	107	13	IPR013783
Domain	FN3_dom	PAPPA2 ROBO4 IL12RB1 CRLF1 IL20RA IL22RA1 MYBPHL	2.01e-04	209	107	7	IPR003961
Domain	TRYPSIN_HIS	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	3.15e-04	103	107	5	IPR018114
Domain	NUT	NUTM2A NUTM2B	3.22e-04	5	107	2	IPR024310
Domain	NUT_N	NUTM2A NUTM2B	3.22e-04	5	107	2	IPR024309
Domain	NUT	NUTM2A NUTM2B	3.22e-04	5	107	2	PF12881
Domain	TRYPSIN_SER	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	3.60e-04	106	107	5	PS00135
Domain	TRYPSIN_HIS	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	3.76e-04	107	107	5	PS00134
Domain	-	PAPPA2 ROBO4 IL12RB1 ADAMTSL1 CRLF1 NTRK2 IL20RA IL22RA1 HAVCR2 LRIG3 VSIG10L MYBPHL	4.13e-04	663	107	12	2.60.40.10
Domain	WxxW_domain	MUC5B MUC5AC	4.80e-04	6	107	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	4.80e-04	6	107	2	PF13330
Domain	Peptidase_S1A	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	4.83e-04	113	107	5	IPR001314
Domain	ACR	ADAM15 ADAMTS13 ADAM12	4.84e-04	27	107	3	SM00608
Domain	ADAM_Cys-rich	ADAM15 ADAMTS13 ADAM12	4.84e-04	27	107	3	IPR006586
Domain	TRYPSIN_DOM	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	5.23e-04	115	107	5	PS50240
Domain	Tryp_SPc	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	5.66e-04	117	107	5	SM00020
Domain	EGF-like_dom	ADAM15 LAMA5 ADAM12 THBD FBN2 MEGF11 MASP2	5.79e-04	249	107	7	IPR000742
Domain	Trypsin	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	6.59e-04	121	107	5	PF00089
Domain	Trypsin_dom	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	6.59e-04	121	107	5	IPR001254
Domain	EGF_1	ADAM15 LAMA5 ADAM12 THBD FBN2 MEGF11 MASP2	6.66e-04	255	107	7	PS00022
Domain	Peptidase_S1_PA	KLK6 PRSS57 TMPRSS11F PRSS36 MASP2	7.10e-04	123	107	5	IPR009003
Domain	EGF-like_CS	ADAM15 LAMA5 ADAM12 THBD FBN2 MEGF11 MASP2	7.64e-04	261	107	7	IPR013032
Domain	EGF_2	ADAM15 LAMA5 ADAM12 THBD FBN2 MEGF11 MASP2	8.35e-04	265	107	7	PS01186
Domain	Cadherin_pro_dom	CDH1 CDH3	8.90e-04	8	107	2	IPR014868
Domain	Cadherin_pro	CDH1 CDH3	8.90e-04	8	107	2	SM01055
Domain	FN3	ROBO4 IL12RB1 CRLF1 IL20RA IL22RA1 MYBPHL	1.01e-03	199	107	6	PS50853
Domain	MBT	MBTD1 L3MBTL1	1.14e-03	9	107	2	SM00561
Domain	MBT	MBTD1 L3MBTL1	1.14e-03	9	107	2	PS51079
Domain	MetalloPept_cat_dom	PAPPA2 ADAM15 ADAMTS13 ADAM12	1.21e-03	81	107	4	IPR024079
Domain	-	PAPPA2 ADAM15 ADAMTS13 ADAM12	1.21e-03	81	107	4	3.40.390.10
Domain	MBT	MBTD1 L3MBTL1	1.42e-03	10	107	2	PF02820
Domain	Interfer-bind	IL20RA IL22RA1	1.42e-03	10	107	2	PF09294
Domain	Mbt	MBTD1 L3MBTL1	1.42e-03	10	107	2	IPR004092
Domain	Interferon/interleukin_rcp_dom	IL20RA IL22RA1	1.42e-03	10	107	2	IPR015373
Domain	DISINTEGRIN_1	ADAM15 ADAMTS13 ADAM12	1.55e-03	40	107	3	PS00427
Domain	Reprolysin	ADAM15 ADAMTS13 ADAM12	1.55e-03	40	107	3	PF01421
Domain	ADAM_MEPRO	ADAM15 ADAMTS13 ADAM12	1.55e-03	40	107	3	PS50215
Domain	DISINTEGRIN_2	ADAM15 ADAMTS13 ADAM12	1.55e-03	40	107	3	PS50214
Domain	Peptidase_M12B	ADAM15 ADAMTS13 ADAM12	1.55e-03	40	107	3	IPR001590
Domain	Disintegrin_dom	ADAM15 ADAMTS13 ADAM12	1.66e-03	41	107	3	IPR001762
Domain	TRYPSIN_SER	KLK6 TMPRSS11F PRSS36 MASP2	1.78e-03	90	107	4	IPR033116
Domain	TIL	MUC5B MUC5AC	2.07e-03	12	107	2	PF01826
Domain	Tissue_fac	IL20RA IL22RA1	2.07e-03	12	107	2	PF01108
Domain	Tissue_factor	IL20RA IL22RA1	2.07e-03	12	107	2	IPR001187
Domain	C8	MUC5B MUC5AC	2.07e-03	12	107	2	PF08742
Domain	IGc2	ROBO4 ADAMTSL1 NTRK2 LRIG3 VSIG10L MYBPHL	2.34e-03	235	107	6	SM00408
Domain	EGF_3	ADAM15 ADAM12 THBD FBN2 MEGF11 MASP2	2.34e-03	235	107	6	PS50026
Domain	Ig_sub2	ROBO4 ADAMTSL1 NTRK2 LRIG3 VSIG10L MYBPHL	2.34e-03	235	107	6	IPR003598
Domain	EGF	ADAM15 LAMA5 THBD FBN2 MEGF11 MASP2	2.34e-03	235	107	6	SM00181
Domain	Unchr_dom_Cys-rich	MUC5B MUC5AC	2.43e-03	13	107	2	IPR014853
Domain	C8	MUC5B MUC5AC	2.43e-03	13	107	2	SM00832
Domain	ZINC_PROTEASE	PAPPA2 ADAM15 ADAMTS13 ADAM12	2.43e-03	98	107	4	PS00142
Domain	-	POLG PIWIL2 ESRP2	2.47e-03	47	107	3	3.30.420.10
Domain	TIL_dom	MUC5B MUC5AC	2.83e-03	14	107	2	IPR002919
Domain	Glyco_hormone_CN	MUC5B MUC5AC	3.25e-03	15	107	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	3.25e-03	15	107	2	PF00007
Domain	VWD	MUC5B MUC5AC	3.70e-03	16	107	2	SM00216
Domain	VWF_type-D	MUC5B MUC5AC	3.70e-03	16	107	2	IPR001846
Domain	VWFD	MUC5B MUC5AC	3.70e-03	16	107	2	PS51233
Domain	VWD	MUC5B MUC5AC	3.70e-03	16	107	2	PF00094
Domain	FN3	PAPPA2 ROBO4 IL12RB1 CRLF1 MYBPHL	4.25e-03	185	107	5	SM00060
Domain	CTCK_1	MUC5B MUC5AC	4.69e-03	18	107	2	PS01185
Domain	ADAM_CR	ADAM15 ADAM12	4.69e-03	18	107	2	PF08516
Domain	Ig_I-set	ROBO4 ADAMTSL1 NTRK2 LRIG3 MYBPHL	4.76e-03	190	107	5	IPR013098
Domain	I-set	ROBO4 ADAMTSL1 NTRK2 LRIG3 MYBPHL	4.76e-03	190	107	5	PF07679
Domain	EGF_extracell	ADAM15 ADAM12 MEGF11	4.94e-03	60	107	3	IPR013111
Domain	EGF_2	ADAM15 ADAM12 MEGF11	4.94e-03	60	107	3	PF07974
Domain	VWC_out	MUC5B MUC5AC	5.22e-03	19	107	2	SM00215
Domain	TSP_1	ADAMTSL1 ADAMTS13 SPON1	5.66e-03	63	107	3	PF00090
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL1 MUC5B ADAMTS13 SPON1 MUC5AC	3.40e-05	68	77	5	M27303
Pathway	KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY	IL20RA IL22RA1 TYK2	4.31e-05	13	77	3	M47556
Pathway	REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING	IL12RB1 CRLF1 TYK2	8.34e-05	16	77	3	MM15127
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTSL1 MUC5B ADAMTS13 SPON1 MUC5AC ALG1	1.29e-04	143	77	6	M27275
Pathway	REACTOME_INTERLEUKIN_20_FAMILY_SIGNALING	IL20RA IL22RA1 TYK2	1.67e-04	20	77	3	MM15496
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	CR1 CR2 THBD MASP2	2.79e-04	58	77	4	M39649
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	CR1 CR2 THBD MASP2	2.98e-04	59	77	4	M48343
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL1 MUC5B ADAMTS13 SPON1 MUC5AC	3.20e-04	109	77	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL1 MUC5B ADAMTS13 SPON1 MUC5AC	3.48e-04	111	77	5	M27416
Pathway	REACTOME_INTERLEUKIN_20_FAMILY_SIGNALING	IL20RA IL22RA1 TYK2	3.72e-04	26	77	3	M27750
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTSL1 GALNS MUC5B ADAMTS13 SPON1 MUC5AC ALG1	4.24e-04	250	77	7	M27554
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	CR1 CR2 THBD MASP2	5.44e-04	69	77	4	M16894
Pathway	REACTOME_INTERLEUKIN_12_SIGNALING	IL12RB1 TYK2	6.08e-04	7	77	2	MM17223
Pathway	REACTOME_INTERLEUKIN_23_SIGNALING	IL12RB1 TYK2	8.07e-04	8	77	2	MM15619
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR1L CR2	3.16e-08	3	111	3	2528587
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR1L CR2	3.16e-08	3	111	3	7528766
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR1L CR2	3.16e-08	3	111	3	2139460
Pubmed	Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.	CR1 CR1L CR2	1.26e-07	4	111	3	16127466
Pubmed	Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.	CR1 CR1L CR2	1.26e-07	4	111	3	30217731
Pubmed	Complement-dependent P-selectin expression and injury following ischemic stroke.	CR1 CR1L CR2	3.15e-07	5	111	3	17082645
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CR1 CR1L CR2	3.15e-07	5	111	3	20962256
Pubmed	Links between signal transduction, transcription and adhesion in epithelial bud development.	LAMA5 CDH1 CDH3	1.75e-06	8	111	3	12646922
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CR1 CR1L CR2	1.75e-06	8	111	3	2564419
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SYNRG ACTR10 BACH2 PKP4 CAMSAP3 MAST2 NCKAP5L CEP164 KIAA1671 ALDH1A2 FBN2 EXOSC6 NEURL4	3.49e-06	853	111	13	28718761
Pubmed	Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.	IL12RB1 MUC5B TYK2 SOCS2 HAVCR2 CDH1 MUC5AC	4.37e-06	204	111	7	20503287
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	IL12RB1 MUC5B TYK2 SOCS2 HAVCR2 CDH1 MUC5AC	4.51e-06	205	111	7	19258923
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	IL12RB1 MUC5B TYK2 SOCS2 HAVCR2 CDH1 MUC5AC	4.81e-06	207	111	7	17703412
Pubmed	Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.	CR1 CR1L CR2	5.12e-06	11	111	3	1543915
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NEMP1 KIF26A SMCHD1 LAMA5 GPATCH2L LRIG3 KMT2C GTF3C2 KBTBD11 ESPL1	7.95e-06	529	111	10	14621295
Pubmed	Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.	CR1 CR1L CR2	8.84e-06	13	111	3	16002709
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	1.01e-05	2	111	2	7513696
Pubmed	Functional identification of transcription control sequences of the mouse Crry gene.	CR1 CR1L	1.01e-05	2	111	2	8335915
Pubmed	Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.	CR1 CR2	1.01e-05	2	111	2	14635039
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	1.01e-05	2	111	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	1.01e-05	2	111	2	14988081
Pubmed	Structural and energetic determinants of adhesive binding specificity in type I cadherins.	CDH1 CDH3	1.01e-05	2	111	2	25253890
Pubmed	p0071 interacts with E-cadherin in the cytoplasm so as to promote the invasion and metastasis of non-small cell lung cancer.	PKP4 CDH1	1.01e-05	2	111	2	28898462
Pubmed	Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.	CR1 CR1L	1.01e-05	2	111	2	10779754
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	1.01e-05	2	111	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	1.01e-05	2	111	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	1.01e-05	2	111	2	24317696
Pubmed	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.	CR1 CR1L	1.01e-05	2	111	2	16444293
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	1.01e-05	2	111	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	1.01e-05	2	111	2	35776514
Pubmed	Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.	CR1 CR1L	1.01e-05	2	111	2	1730912
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	1.01e-05	2	111	2	24327612
Pubmed	Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.	CR1 CR1L	1.01e-05	2	111	2	19740350
Pubmed	Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblasts.	CDH1 CDH3	1.01e-05	2	111	2	9682977
Pubmed	[Cadherins E and P expression in the molecular types of breast cancer].	CDH1 CDH3	1.01e-05	2	111	2	26299056
Pubmed	Expression and functional role of E- and P-cadherins in mouse mammary ductal morphogenesis and growth.	CDH1 CDH3	1.01e-05	2	111	2	7781895
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	1.01e-05	2	111	2	28607090
Pubmed	Thrombomodulin reduces tumorigenic and metastatic potential of lung cancer cells by up-regulation of E-cadherin and down-regulation of N-cadherin expression.	THBD CDH1	1.01e-05	2	111	2	27223053
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	1.01e-05	2	111	2	31030254
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	1.01e-05	2	111	2	23527003
Pubmed	The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.	CR1 CR2	1.01e-05	2	111	2	11981823
Pubmed	Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.	CDH1 CDH3	1.01e-05	2	111	2	12021924
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	1.01e-05	2	111	2	16540890
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	1.01e-05	2	111	2	27845589
Pubmed	E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements.	CDH1 CDH3	1.01e-05	2	111	2	32572153
Pubmed	Differential expression of E-cadherin and P-cadherin in pT3 prostate cancer: correlation with clinical and pathological features.	CDH1 CDH3	1.01e-05	2	111	2	30006753
Pubmed	Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.	CR1 CR1L	1.01e-05	2	111	2	2952719
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	1.01e-05	2	111	2	27435107
Pubmed	Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification.	CDH1 CDH3	1.01e-05	2	111	2	10545227
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	1.01e-05	2	111	2	26871672
Pubmed	Differential spatiotemporal expression of E- and P-cadherin during mouse tooth development.	CDH1 CDH3	1.01e-05	2	111	2	8619966
Pubmed	Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.	CR1 CR2	1.01e-05	2	111	2	1708808
Pubmed	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.	CR1 CR1L	1.01e-05	2	111	2	12767833
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	1.01e-05	2	111	2	11587997
Pubmed	Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces.	CDH1 CDH3	1.01e-05	2	111	2	23277553
Pubmed	Reciprocal altered expression of E-cadherin and P-cadherin in mucous membrane pemphigoid.	CDH1 CDH3	1.01e-05	2	111	2	21781454
Pubmed	Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis.	CDH1 CDH3	1.01e-05	2	111	2	2806126
Pubmed	Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesis.	CDH1 CDH3	1.01e-05	2	111	2	2806125
Pubmed	Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.	CR1 CR1L	1.01e-05	2	111	2	20484840
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	1.01e-05	2	111	2	34656442
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	1.01e-05	2	111	2	34058148
Pubmed	Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.	CR1 CR1L	1.01e-05	2	111	2	17674370
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	1.01e-05	2	111	2	14718370
Pubmed	A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos.	CDH1 CDH3	1.01e-05	2	111	2	3539943
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	1.01e-05	2	111	2	21653907
Pubmed	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.	CR1 CR1L	1.01e-05	2	111	2	11698469
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	1.01e-05	2	111	2	36427316
Pubmed	Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones.	CR1 CR1L	1.01e-05	2	111	2	34709768
Pubmed	The murine complement regulator Crry: new insights into the immunobiology of complement regulation.	CR1 CR1L	1.01e-05	2	111	2	11915940
Pubmed	Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecules.	CDH1 CDH3	1.01e-05	2	111	2	3428270
Pubmed	Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.	CR1 CR1L	1.01e-05	2	111	2	7691944
Pubmed	Comparative functional evolution of human and mouse CR1 and CR2.	CR1 CR2	1.01e-05	2	111	2	18713965
Pubmed	The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1.	CR1 CR1L	1.01e-05	2	111	2	2911011
Pubmed	E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor.	KLF6 CDH1	1.01e-05	2	111	2	16702959
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	1.01e-05	2	111	2	23272068
Pubmed	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.	CR1 CR1L	1.01e-05	2	111	2	12902517
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	1.01e-05	2	111	2	27729120
Pubmed	Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.	CR1 CR1L	1.01e-05	2	111	2	17015675
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	1.01e-05	2	111	2	36111525
Pubmed	Similarities in structure and expression between mouse P-cadherin, chicken B-cadherin and frog XB/U-cadherin.	CDH1 CDH3	1.01e-05	2	111	2	7743137
Pubmed	Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.	CR1 CR1L	1.01e-05	2	111	2	23153828
Pubmed	Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.	CR1 CR2	1.01e-05	2	111	2	37833411
Pubmed	[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].	CR1 CR2	1.01e-05	2	111	2	26189291
Pubmed	Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice.	CR1 CR1L	1.01e-05	2	111	2	12973023
Pubmed	Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.	CR1 CR2	1.01e-05	2	111	2	23440418
Pubmed	Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.	CR1 CR1L	1.01e-05	2	111	2	10586048
Pubmed	In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.	CR1 CR1L	1.01e-05	2	111	2	16301687
Pubmed	Differential Expression of E-Cadherin and P-Cadherin in Breast Cancer Molecular Subtypes.	CDH1 CDH3	1.01e-05	2	111	2	32988879
Pubmed	Expression dynamics of Crry at the implantation sites in normal pregnancy and response against miscarriage induction.	CR1 CR1L	1.01e-05	2	111	2	36450590
Pubmed	Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.	CR1 CR1L	1.01e-05	2	111	2	16301324
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	1.01e-05	2	111	2	32348677
Pubmed	Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues.	CDH1 CDH3	1.01e-05	2	111	2	2793940
Pubmed	Overexpression of the Oncogenic Variant (KLF6-SV1) in Young NPC Patients and Correlation with Lack of E-Cadherin.	KLF6 CDH1	1.01e-05	2	111	2	29854578
Pubmed	The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes.	CR1 CR1L	1.01e-05	2	111	2	2307848
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	1.01e-05	2	111	2	24332705
Pubmed	Complement regulatory protein Crry/p65 costimulation expands natural treg cells with enhanced suppressive properties in proteoglycan-induced arthritis.	CR1 CR1L	1.01e-05	2	111	2	21380996
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SYNRG KIF26A POLG LAMA5 MAST2 TYK2 ESRP2 KMT2C CDK13 TMEM132A EXOSC6 KBTBD11 ESPL1 RIC1	1.18e-05	1105	111	14	35748872
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	ROBO4 ADAMTSL1 PRSS57 CRLF1 SHC4 IL20RA ADAMTS13 ADAM12 LRIG3 LYPD5 ADGRF3 MEGF11 ALG1	1.62e-05	985	111	13	12975309
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	WRNIP1 MUC5B NCKAP5L PTH1R CEP164 TMEM132A	1.85e-05	170	111	6	23314748
Pubmed	NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.	DCT CDH1 CDH3	2.49e-05	18	111	3	23389444
Interaction	CR1 interactions	CR1 CR1L CR2	7.99e-06	8	107	3	int:CR1
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	ESRP2 EXOSC6 HSD11B2 CDH1 CDH3	8.68e-05	183	111	5	chr16q22
Cytoband	16q22.1	ESRP2 EXOSC6 CDH1 CDH3	1.53e-04	110	111	4	16q22.1
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 CR1 CR1L CR2 MASP2	4.05e-06	57	76	5	1179
GeneFamily	Proteases, serine	KLK6 PRSS57 TMPRSS11F PRSS36	1.42e-04	63	76	4	738
GeneFamily	CD molecules\|Type I classical cadherins	CDH1 CDH3	1.73e-04	5	76	2	1185
GeneFamily	Complement system\|Sushi domain containing	CR1 CR1L CR2	4.61e-04	36	76	3	492
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 ADAMTSL1 NTRK2 LRIG3 MYBPHL	5.84e-04	161	76	5	593
GeneFamily	Sterile alpha motif domain containing\|MBT domain containing	MBTD1 L3MBTL1	6.16e-04	9	76	2	1263
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL12RB1 IL20RA IL22RA1	7.28e-04	42	76	3	602
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	3.48e-03	21	76	2	648
GeneFamily	Fibronectin type III domain containing	ROBO4 IL12RB1 CRLF1 MYBPHL	4.62e-03	160	76	4	555
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM15 ADAM12	5.72e-03	27	76	2	47
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IL12RB1 CR1 CR2 CD163 THBD CDH1	6.25e-03	394	76	6	471
ToppCell	wk_15-18-Epithelial-Distal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TTYH1 CRLF1 CAMSAP3 LAMA5 ESRP2 HSD11B2 CDH1 CDH3	3.52e-08	197	111	8	b7aff83c27606d87565382a768119a863fe1c294
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 ALDH1A2 SPAG17 CDH3 MEGF11	5.03e-07	190	111	7	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 ALDH1A2 SPAG17 CDH3 MEGF11	5.21e-07	191	111	7	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 ALDH1A2 SPAG17 CDH3 MEGF11	5.21e-07	191	111	7	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	NS-critical-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 ADAM15 MUC5B ESRP2 LRIG3 CDH3 MUC5AC	6.41e-07	197	111	7	a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	RNF152 CUL7 DND1 TYK2 GTF3C2 ZNF283	2.55e-06	155	111	6	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	droplet-Liver-Npc-21m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 CHRM1 GPATCH2L ALDH1A2 ZFR2	2.75e-06	157	111	6	264b22d0ffc43049161843bb55d2eccbf5fca575
ToppCell	droplet-Liver-Npc-21m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ADAM15 CHRM1 GPATCH2L ALDH1A2 ZFR2	2.75e-06	157	111	6	67945d37027be62c880d3072afa7ca7e97c76c20
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 SOCS2 THBD ALDH1A2 ZFR2 KBTBD11	5.48e-06	177	111	6	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRLF1 MUC5B ITPRID1 ALDH1A2 FBN2 CDH3	5.66e-06	178	111	6	b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRLF1 MUC5B ITPRID1 ALDH1A2 FBN2 CDH3	5.66e-06	178	111	6	fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	TCAF2 TRPM7 POLG ZNF397 CUL7 ADGRF3	5.84e-06	179	111	6	c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 TCAF2 KIF26A ESRP2 TMEM132A CDH3	6.22e-06	181	111	6	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CRLF1 KLF6 CAMSAP3 ESRP2 CDH1 CDH3	7.50e-06	187	111	6	baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROBO4 ADAMTSL1 OAS3 KIAA1671 THBD CIITA	7.50e-06	187	111	6	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ROBO4 ADAMTSL1 ADAM15 CHRM1 KIAA1671 TMEM132A	7.73e-06	188	111	6	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 SHC4 ADAM12 DCT ALDH1A2 CDH1	7.73e-06	188	111	6	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6 CDH3	7.73e-06	188	111	6	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 SHC4 ADAM12 DCT ALDH1A2 CDH1	7.73e-06	188	111	6	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CRLF1 CAMSAP3 IL22RA1 HSD11B2 CDH1 CDH3	7.97e-06	189	111	6	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	CRLF1 LAMA5 LRIG3 TMEM132A CDH1 CDH3	7.97e-06	189	111	6	8030a353473da34ae92429f2d822171a2e94248f
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6 MEGF11	8.46e-06	191	111	6	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6 MEGF11	8.46e-06	191	111	6	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CRLF1 LAMA5 ESRP2 HSD11B2 CDH1 CDH3	8.72e-06	192	111	6	fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CRLF1 LAMA5 ESRP2 HSD11B2 CDH1 CDH3	8.72e-06	192	111	6	87b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROBO4 RNF152 KIF26A PKP4 KIAA1671 THBD	8.72e-06	192	111	6	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CRLF1 LAMA5 ESRP2 ALDH1A2 CDH1 CDH3	8.98e-06	193	111	6	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	facs-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDH ADAM15 ESRP2 THBD LYPD5 CDH1	8.98e-06	193	111	6	33437fdb417d78463caee14a9f0e094da1733829
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CRLF1 LAMA5 ESRP2 ALDH1A2 CDH1 CDH3	8.98e-06	193	111	6	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCAF2 ROBO4 ADAMTSL1 ADAM15 THBD SPON1	8.98e-06	193	111	6	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CRLF1 CAMSAP3 ESRP2 HSD11B2 CDH1 CDH3	9.25e-06	194	111	6	20f81f457ab0a404600effe8beb91fe73d1cfc10
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TTYH1 KLK6 MUC5B ITPRID1 TMEM132A HSD11B2	9.25e-06	194	111	6	e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 CRLF1 CAMSAP3 LAMA5 CDH1 CDH3	9.52e-06	195	111	6	0e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 PKP4 PTH1R ALDH1A2 SPON1 CDH3	9.80e-06	196	111	6	d688350aadc622984d612ae6b2fd7c0113a4ec0f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6 ALDH1A2	9.80e-06	196	111	6	e02301642243df483fd066d978317c113c04692b
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRLF1 LAMA5 ESRP2 HSD11B2 CDH1 CDH3	1.07e-05	199	111	6	debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 CRLF1 LAMA5 ESRP2 CDH1 CDH3	1.07e-05	199	111	6	af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 SOCS2 THBD ALDH1A2 LYPD5 KBTBD11	1.10e-05	200	111	6	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	wk_08-11-Epithelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRLF1 LAMA5 ESRP2 HSD11B2 CDH1 CDH3	1.10e-05	200	111	6	445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 KIF26A ADAM15 PKP4 KIAA1671 THBD	1.10e-05	200	111	6	90061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 SOCS2 THBD ALDH1A2 LYPD5 KBTBD11	1.10e-05	200	111	6	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LAMA5 TMPRSS11F DCT ALDH1A2 CDH1	4.21e-05	154	111	5	8a643d91896af9b630a715fb284c1523d01ad1a3
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	IL12RB1 TDH DCT ADGRF3	4.57e-05	79	111	4	cd182dbc8d0ccc2406e78c9ba71476c1f463359b
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	IL12RB1 TDH DCT ADGRF3	4.57e-05	79	111	4	bcb9181d7de7a385b890523299f8290836aa536e
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTYH1 LAMA5 CR1L LYPD5 ESPL1	5.20e-05	161	111	5	8ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B ITPRID1 ALDH1A2 CDH1 MUC5AC	5.85e-05	165	111	5	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B ITPRID1 ALDH1A2 CDH1 MUC5AC	5.85e-05	165	111	5	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B ITPRID1 ALDH1A2 CDH1 MUC5AC	5.85e-05	165	111	5	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 RNF152 KIF26A LYPD5 KBTBD11	5.85e-05	165	111	5	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	ROBO4 RNF152 KIF26A SGCG KBTBD11	6.19e-05	167	111	5	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RNF152 ANG CUL7 DND1 ZNF283	6.19e-05	167	111	5	6c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RNF152 ANG CUL7 DND1 ZNF283	6.37e-05	168	111	5	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF2 NTRK2 IL20RA ADAM12 L3MBTL1	6.55e-05	169	111	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADAMTS13 GREB1L HAVCR2 CCNE2 TMEM132A	7.12e-05	172	111	5	68fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMA5 MUC5B OSBPL7 CDH1 MUC5AC	7.12e-05	172	111	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ROBO4 IL12RB1 ADAMTSL1 ALDH1A2 KBTBD11	7.12e-05	172	111	5	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM15 CHRM1 IL22RA1 THBD ADGRF3	7.12e-05	172	111	5	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTSL1 DCT ARHGAP6 FBN2 SPON1	7.52e-05	174	111	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BACH2 ITPRID1 CR2 ADAM12 CIITA	7.52e-05	174	111	5	8bdf5a97faf1cf0426d1a8851f8a3e27578f7598
ToppCell	facs-Marrow-KLS-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 SOCS2 SPON1 LYPD5 MASP2	7.52e-05	174	111	5	0cf40ce9d9ad926c4909665aaa224694b5d970cb
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BACH2 ITPRID1 CR2 ADAM12 CIITA	7.52e-05	174	111	5	fbf998dd33ac27dad7639ea85fca393ba2835307
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAPPA2 ADAMTSL1 SGCG XKR8 ARHGAP6	7.72e-05	175	111	5	90e29945aa861082c94bb4f331161adc3a6ef899
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	SGCG IL20RA CR1 KBTBD11 HSD11B2	7.72e-05	175	111	5	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	CRLF1 LAMA5 LRIG3 CDH1 CDH3	7.93e-05	176	111	5	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	SMCHD1 OAS3 HAVCR2 FBN2 ESPL1	8.15e-05	177	111	5	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTSL1 SGCG XKR8 ARHGAP6 MEGF11	8.15e-05	177	111	5	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ESRP2 ALDH1A2 CIITA CDH1	8.29e-05	92	111	4	bbaf5a131f860198840e34843b7c841bcc98d9c4
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	ESRP2 ALDH1A2 CIITA CDH1	8.29e-05	92	111	4	e6aa2b8ca9235a7291ee41d976b886fec185835d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RHBDL1 IL20RA PRSS36 CD163 CIITA	8.37e-05	178	111	5	24e8c62060455159235985f456af0c5023a7f3f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RHBDL1 IL20RA PRSS36 CD163 CIITA	8.37e-05	178	111	5	4f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTSL1 SGCG XKR8 ARHGAP6 MEGF11	8.59e-05	179	111	5	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PAPPA2 SGCG CD163 ESRP2	9.02e-05	94	111	4	d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PAPPA2 SGCG CD163 ESRP2	9.02e-05	94	111	4	dfc3f7977b9df433009d1d2d465b64a2de5806e2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GREB1L ARHGAP6 HSD11B2 SPAG17 CDH1	9.05e-05	181	111	5	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM7 PTH1R NUTM2E ARHGAP6 HSD11B2	9.05e-05	181	111	5	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 BACH2 PKP4 PTH1R CDH3	9.05e-05	181	111	5	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 RNF152 LAMA5 PTH1R ARHGAP6	9.29e-05	182	111	5	ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 KIF26A ADAM15 PKP4 THBD	9.29e-05	182	111	5	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	droplet-Lung-nan-21m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 CAMSAP3 ITPRID1 ALDH1A2 CDH1	9.29e-05	182	111	5	40539ade8c3cd12b61f1cd0d493828e58282796b
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MUC5B GREB1L ESRP2 CDH1 MUC5AC	9.29e-05	182	111	5	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CRLF1 LAMA5 ESRP2 CDH1 CDH3	9.53e-05	183	111	5	0cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 RNF152 LAMA5 PTH1R ARHGAP6	9.78e-05	184	111	5	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 RNF152 LAMA5 PTH1R ARHGAP6	9.78e-05	184	111	5	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6	9.78e-05	184	111	5	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MUC5B CD163 CCNE2 SPAG17 ESPL1	1.00e-04	185	111	5	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PAPPA2 SGCG PTH1R SOCS2 FBN2	1.00e-04	185	111	5	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	droplet-Fat-Mat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 KIF26A PKP4 THBD CDH3	1.00e-04	185	111	5	d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCell	facs-Kidney-nan-18m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEMP1 KLF6 CR2 CIITA MYBPHL	1.00e-04	185	111	5	a3b937163346d729115e6335336e33d3e71fccb0
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 RNF152 ADAM15 KIAA1671 KBTBD11	1.00e-04	185	111	5	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TCAF2 TRPM7 ZNF397 CUL7 ADGRF3	1.03e-04	186	111	5	bca5215d406f1785bf3a420201d5686071fcaca5
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CRLF1 HSD11B2 CDH1 CDH3 MEGF11	1.03e-04	186	111	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PAPPA2 NTRK2 FBN2 SPON1 HSD11B2	1.05e-04	187	111	5	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	E12.5-Epithelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CRLF1 KLF6 ESRP2 CDH1 CDH3	1.05e-04	187	111	5	29ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CRLF1 CAMSAP3 HSD11B2 CDH1 CDH3	1.05e-04	187	111	5	c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell	COVID-19-kidney-Mito-rich_Distal\|kidney / Disease (COVID-19 only), tissue and cell type	PAPPA2 NTRK2 PKP4 PTH1R ARHGAP6	1.05e-04	187	111	5	2ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RNF152 CR1 CD163 THBD KBTBD11	1.05e-04	187	111	5	3b1439018e265a61d9599e307a202e3c2f60ed32
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|IPF / Disease state, Lineage and Cell class	CRLF1 LAMA5 TMEM132A CDH1 CDH3	1.05e-04	187	111	5	19d6a404fc3651d98a93e3848e372df51a239c57
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RNF152 CR1 CD163 THBD KBTBD11	1.05e-04	187	111	5	e99bc27d212c74da37770297122a4b30445ccd0d
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 RNF152 KIF26A ADAM15 KIAA1671	1.05e-04	187	111	5	d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ROBO4 ADAM15 NTRK2 KIAA1671 THBD	1.05e-04	187	111	5	106f50ad85a92403037214f0e94702230284837f
Computational	Genes in the cancer module 27.	IL12RB1 CRLF1 NTRK2 CR1 CR2 CHRM1 PTH1R CD163 THBD CIITA	4.82e-05	355	65	10	MODULE_27
Drug	Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A	ANG NTRK2 OAS3 MAST2 CEP164 ADRA1B L3MBTL1 CDK13 MASP2	4.23e-07	197	108	9	3568_UP
Drug	Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A	PAPPA2 MUC5B PIWIL2 ADAM12 PTH1R GREB1L ARHGAP6 CIITA	4.41e-06	196	108	8	5606_UP
Drug	Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A	PAPPA2 KLF6 NTRK2 POLG BACH2 CUL7 MAST2 MASP2	4.58e-06	197	108	8	4555_UP
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; HL60; HT_HG-U133A	PAPPA2 ANG MAST2 DCT ESRP2 ALDH1A2 L3MBTL1 SPON1	4.58e-06	197	108	8	3069_UP
Drug	Scopoletin [92-61-5]; Down 200; 20.8uM; HL60; HT_HG-U133A	PAPPA2 KLF6 ADAM15 CR1 MAST2 CEP164 GPATCH2L CDK13	4.75e-06	198	108	8	3131_DN
Drug	Suloctidil [54063-56-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A	PAPPA2 IL12RB1 ANG KLF6 CUL7 SOCS2 CIITA	1.69e-05	170	108	7	5021_UP
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; MCF7; HT_HG-U133A	NEMP1 KLF6 GTF3C2 CDK13 CCNE2 CDH1 CWF19L1	3.23e-05	188	108	7	2805_DN
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	ANG KLF6 NTRK2 MUC5B GPATCH2L L3MBTL1 CDH1	3.70e-05	192	108	7	1221_UP
Drug	5-aza-2′-deoxycytidine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	IL12RB1 MBTD1 SGCG GPATCH2L GREB1L L3MBTL1 MUC5AC	4.08e-05	195	108	7	920_UP
Drug	Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A	KLF6 ADAM15 NTRK2 PKP4 L3MBTL1 OSBPL7 CDH1	4.21e-05	196	108	7	4324_UP
Drug	Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A	NTRK2 PIWIL2 CR1 IL22RA1 CEP164 THBD L3MBTL1	4.35e-05	197	108	7	4239_UP
Drug	Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A	ROBO4 ADAMTS13 CUL7 MAST2 CIITA SPON1 HSD11B2	4.35e-05	197	108	7	3554_UP
Drug	Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; HL60; HT_HG-U133A	NEMP1 KLF6 POLG PKP4 ADAM12 GPATCH2L CDK13	4.49e-05	198	108	7	2578_UP
Drug	Alfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A	IL12RB1 KLK6 ANG OAS3 CEP164 ZFR2 SPON1	4.49e-05	198	108	7	3135_UP
Disease	Familial Thrombotic Thrombocytopenic Purpura	ADAMTS13 THBD	8.22e-05	4	110	2	C1956258
Disease	Congenital Thrombotic Thrombocytopenic Purpura	ADAMTS13 THBD	8.22e-05	4	110	2	C1268935
Disease	Purpura, Thrombotic Thrombocytopenic	ADAMTS13 THBD	8.22e-05	4	110	2	C0034155
Disease	kallikrein-7 measurement	KLK6 CD163	1.37e-04	5	110	2	EFO_0008195
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	1.37e-04	5	110	2	C0206630
Disease	level of Phosphatidylcholine (15:0_18:1) in blood serum	ALDH1A2 GTF3C2	1.37e-04	5	110	2	OBA_2045064
Disease	Agouti-related protein measurement	ESRP2 CDH1 CDH3	1.38e-04	27	110	3	EFO_0008016
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	2.05e-04	6	110	2	C0334488
Disease	level of Phosphatidylcholine (16:0_18:1) in blood serum	ALDH1A2 GTF3C2	2.05e-04	6	110	2	OBA_2045070
Disease	blood sedimentation	CR1 CR1L	2.86e-04	7	110	2	EFO_0004304
Disease	COVID-19 symptoms measurement	MUC5B TYK2 MUC5AC	3.02e-04	35	110	3	EFO_0600019
Disease	Malignant tumor of prostate	KLF6 CDH1	4.87e-04	9	110	2	cv:C0376358
Disease	Diabetes, Autoimmune	BACH2 TYK2 HSD11B2	5.97e-04	44	110	3	C0205734
Disease	Brittle diabetes	BACH2 TYK2 HSD11B2	5.97e-04	44	110	3	C0342302
Disease	Diabetes Mellitus, Sudden-Onset	BACH2 TYK2 HSD11B2	5.97e-04	44	110	3	C4554117
Disease	Diabetes Mellitus, Ketosis-Prone	BACH2 TYK2 HSD11B2	5.97e-04	44	110	3	C3837958
Disease	hepatocellular carcinoma (is_implicated_in)	POLG CEP164 HAVCR2 CDK13 CDH1	5.98e-04	181	110	5	DOID:684 (is_implicated_in)
Disease	Diabetes Mellitus, Insulin-Dependent	BACH2 TYK2 HSD11B2	6.38e-04	45	110	3	C0011854
Disease	pulmonary fibrosis	MUC5B MUC5AC	7.41e-04	11	110	2	EFO_0009448
Disease	vitamin D measurement, COVID-19	OAS3 ALDH1A2 SPON1	8.20e-04	49	110	3	EFO_0004631, MONDO_0100096
Disease	susceptibility to measles measurement	PAPPA2 SGCG KIAA1671	8.20e-04	49	110	3	EFO_0008414
Disease	level of Sphingomyelin (d34:2) in blood serum	ALDH1A2 RIC1	1.05e-03	13	110	2	OBA_2045174
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	GREB1L ALDH1A2	1.05e-03	13	110	2	OBA_2045082
Disease	polyp of colon	LAMA5 CDH1 CDH3	1.21e-03	56	110	3	MONDO_0021400
Disease	idiopathic pulmonary fibrosis	TTYH1 MUC5B MUC5AC	1.27e-03	57	110	3	EFO_0000768
Disease	systemic lupus erythematosus, COVID-19	ADAM15 OAS3 TYK2	1.34e-03	58	110	3	MONDO_0007915, MONDO_0100096
Disease	cystic fibrosis (is_marker_for)	MUC5B HAVCR2 MUC5AC	1.62e-03	62	110	3	DOID:1485 (is_marker_for)
Disease	Ulcerative Colitis	CDH1 CDH3 MASP2	1.70e-03	63	110	3	C0009324
Disease	pelvic organ prolapse	ADAMTSL1 LAMA5 DCT FBN2	1.71e-03	136	110	4	EFO_0004710
Disease	cholangiocarcinoma (is_marker_for)	MUC5B OSBPL7 MUC5AC	1.78e-03	64	110	3	DOID:4947 (is_marker_for)
Disease	Benign neoplasm of stomach	KLF6 CDH1	1.81e-03	17	110	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	KLF6 CDH1	1.81e-03	17	110	2	C0496905
Disease	Carcinoma in situ of stomach	KLF6 CDH1	1.81e-03	17	110	2	C0154060
Disease	Hypogammaglobulinemia	BACH2 CR2	1.81e-03	17	110	2	C0086438
Disease	progression free survival, ovarian carcinoma	NTRK2 ACTR10	2.03e-03	18	110	2	EFO_0001075, EFO_0004920
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	BACH2 PRSS36	2.03e-03	18	110	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	respiratory system disease	BACH2 OSBPL7 MUC5AC RIC1	2.16e-03	145	110	4	EFO_0000684
Disease	Stomach Carcinoma	KLF6 CDH1	2.76e-03	21	110	2	C0699791
Disease	prostate cancer (is_marker_for)	KLK6 KMT2C CDK13 CDH1	2.81e-03	156	110	4	DOID:10283 (is_marker_for)
Disease	Parkinson's disease (is_implicated_in)	KLK6 ANG POLG	2.91e-03	76	110	3	DOID:14330 (is_implicated_in)
Disease	idiopathic pulmonary fibrosis (is_marker_for)	NTRK2 THBD	3.31e-03	23	110	2	DOID:0050156 (is_marker_for)
Disease	Neoplasm of the genitourinary tract	KLF6 CDH1	3.60e-03	24	110	2	cv:C0042065

Protein segments in the cluster

Peptide	Gene	Start	Entry
QWDGVGPIPGLSKSP	PKP4	801	Q99569
KIPSPGGGCVTWSCI	TTYH1	81	Q9H313
AFAPICNPVLCPWGK	ESD	171	P10768
PVPKGLWVGAGQSLP	BACH2	461	Q9BYV9
CPIPLSSSFGRWPKG	ADGRF3	66	Q8IZF5
NPPGLPSIAVCWFVG	ALG1	131	Q9BT22
PALIVKGEPPWCSQQ	C2orf48	81	Q96LS8
CQSLWGPGAQPAAPL	ADAM15	531	Q13444
PIGVCGQIIPWNFPL	ALDH1A2	176	O94788
CPAAGEVSNKLPKWP	CIITA	321	P33076
NCWPPVLSGGISPCI	CCNE2	56	O96020
QQCVTLWGPGAKPAP	ADAM12	531	O43184
ISIGPLLGWKEPAPN	ADRA1B	176	P35368
LAWPVLVGPQDGGCP	CACTIN-AS1	161	Q8N1I8
LPWGVKVSIIQPGCF	HSD11B2	251	P80365
AAWVIPGPTTGPKAA	CAMSAP3	741	Q9P1Y5
GSPCPAVWPDVIKLP	CDK13	931	Q14004
PPAKANCVAWLGGAI	ACTR10	346	Q9NZ32
LPKPVTVRGCWAGPC	ADAMTS13	1116	Q76LX8
WAGPCVGQGTPSLVP	ADAMTS13	1126	Q76LX8
RKDGCWAPTGTPPTA	MUC5B	5256	Q9HC84
GWPKRLLCPLGSPAE	RIC1	6	Q4ADV7
TAWAGLQGPPLPTLC	ANO7	6	Q6IWH7
VWALSNLCRGKNPPP	KPNA6	231	O60684
PGWIGKDCSQACPPG	MEGF11	686	A6BM72
CLDPPLQTVPKGGWK	KMT2C	1036	Q8NEZ4
DGACIPRSPWKPGTL	KIAA1671	551	Q9BY89
KSPWPACGPRNGLVG	NCKAP5L	1061	Q9HCH0
PVGWCAASGKPLVPP	MBTD1	231	Q05BQ5
AWAKLGPTPLSNCPV	ITPRID1	1021	Q6ZRS4
LQCIAGGSPPPKLNW	LRIG3	716	Q6UXM1
VGCGLSLAPGPAPTW	EXOSC6	181	Q5RKV6
LGCPIKGHPVPNITW	ADAMTSL1	1416	Q8N6G6
ILLTSPWPKCVGNFG	CWF19L1	151	Q69YN2
HPVGWCQKQGKPLTP	L3MBTL1	466	Q9Y468
KVAVSPAVGPGPWGS	NEMP1	6	O14524
LVLEAWQKGPCPPRG	CUL7	1591	Q14999
WQKGPCPPRGLVSSL	CUL7	1596	Q14999
WRKVAGATVGPGPVP	POLG	6	P54098
VQVEGSPWVPCLPGK	LMLN2	566	A0A1B0GTW7
ECPPVAGPDGLSKAW	KIF26A	261	Q9ULI4
GCPNAVPPRKKGETW	MUC5AC	4851	P98088
QVTTCKLHGGSPWPP	ANG	101	P03950
DRCKPGFWGLSPSNP	LAMA5	756	O15230
GAQCVPVSPGQLPWL	GREB1L	496	Q9C091
WGRAVPCVSGGLPKP	IL20RA	26	Q9UHF4
GPGKPAAAAAWIQGP	ARHGAP6	886	O43182
WPTGGSNLCPPELAK	PRSS36	821	Q5K4E3
ISCVPPAKLQGLSPW	PAPPA2	1491	Q9BXP8
WAPPGCEKLGKCLTP	GALNS	496	P34059
CWKGLLLPSSEEPGP	ESPL1	1801	Q14674
PLKNVGCLIGPDNIW	CC2D2A	1426	Q9P2K1
EGVWTPPVPQCKVAA	CR2	456	P20023
QVGIWSGPAPQCIIP	CR1	221	P17927
QVGIWSGPAPQCIIP	CR1	671	P17927
QVGIWSGPAPQCIIP	CR1	1121	P17927
IWSGPAPQCIIPNKC	CR1L	216	Q2VPA4
PNITVLAPGKGPWQV	CHRM1	11	P11229
TPSSPWKLGDCGPQD	IL12RB1	176	P42701
PGPPQSIKLVDVWGF	MYBPHL	146	A2RUH7
CGSVATPLGPKWPEP	MASP2	11	O00187
TLVRKGCWTGPPAGQ	LYPD5	71	Q6UWN5
GATDPIPPEGCWKAQ	MAST2	1606	Q6P0Q8
PVFLTKCLGIGPAGW	DND1	271	Q8IYX4
GPSPWGLLESLVCPK	IL22RA1	526	Q8N6P7
CVPGFTVPNLLPKWA	GPATCH2L	256	Q9NWQ4
GKAWGNPCETCPPVN	FBN2	1611	P35556
QLGCPTAIKAPGWAN	CD163	91	Q86VB7
VGLPPEKPVNISCWS	CRLF1	131	O75462
TCPGPWKGGFILPVL	CDH3	646	P22223
VDGIKESVCWGPPPA	NEURL4	1316	Q96JN8
WVIPPISCPENEKGP	CDH1	156	P12830
RGPTPGGQCIWKPNS	OSBPL7	711	Q9BZF2
PVQSWKGPGLPRAGC	OAS3	336	Q9Y6K5
KGFCPQDRPPSLGSW	FAM180B	161	Q6P0A1
WQAPGALCGGVVCPP	NUTM2A	231	Q8IVF1
WQAPGALCGGVVCPP	NUTM2B	231	A6NNL0
WQAPGALCGGVVCPP	NUTM2E	231	B1AL46
FWIAPPAGTGCVILK	SPON1	146	Q9HCB6
LWIGLQLPPGCGDPK	THBD	86	P07204
PGPPGNKDLCFTWRE	SMCHD1	1226	A6NHR9
CPWCRGVTKLPPGFS	RNF152	51	Q8N8N0
KGQDWPPGSGSLPCA	TMEM132A	146	Q24JP5
FWINCVEPKPPGLVL	SYNRG	1296	Q9UMZ2
AVSWLCPCPGAPVGV	TCAF2	81	A6NFQ2
KAPVPPQVTLWICGL	NBPF7P	291	P0C2Y1
GCWPQASKPLDPALG	PIWIL2	26	Q8TC59
TPAAPGNLVPVCWGK	HAVCR2	41	Q8TDQ0
GNLVPVCWGKGACPV	HAVCR2	46	Q8TDQ0
LPVKPPAGSWGAQII	PRSS57	21	Q6UWY2
INKCTGAIWGLPLPT	SOCS2	171	O14508
ADPCPWPGSLVVLFG	ESRP2	21	Q9H6T0
TGTGPLSQKCWEPEP	RHBDL1	36	O75783
AKQWSPCVAPLRLPG	KBTBD11	531	O94819
TVCLPKLVQGTWGPS	SGCG	241	Q13326
GPPFGTQIWKGLCIE	SPAG17	1731	Q6Q759
LKPGNGTVFVSWVPP	ROBO4	356	Q8WZ75
APLPGEWKPCQDITG	CEP164	56	Q9UPV0
WCIPFTVKGNPKPAL	NTRK2	301	Q16620
PLGSPWHCGKAPETV	SHC4	486	Q6S5L8
AAGCRPQWGKPAQPK	ZFR2	411	Q9UPR6
IVSWGQSCALPKKPG	TMPRSS11F	406	Q6ZWK6
AKPVATAPIPGTPWC	TCERG1	521	O14776
LCWPLGAPGEVVAVP	PTH1R	116	Q03431
FGWTGPNCERKKPPV	DCT	111	P40126
IPSLILWGPPGCGKT	WRNIP1	261	Q96S55
ASPQGPAVPWKDLTC	ZNF397	141	Q8NF99
VGLDLQPWGCQPKSV	TMEM89	31	A2RUT3
CPSGAWELPGTPRKA	GTF3C2	476	Q8WUA4
QGLGVEVPSIKPPSW	VSIG10L	46	Q86VR7
VTLLCAWPGGLPPAQ	VSIG10L2	346	P0DP72
VIPQICGPGTWLTPF	TRPM7	1061	Q96QT4
GQSPACGCWTPVLPV	TDH	11	Q8IZJ6
IPWLAPECLPGGANS	TYK2	776	P29597
PSGIPLQLWLPVGCG	XKR8	311	Q9H6D3
VQWCDLGSLQAPPPG	ZNF283	11	Q8N7M2
LWGCVPGELPSPGKV	KLF6	161	Q99612
VSWGNIPCGSKEKPG	KLK6	211	Q92876