Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidic acid binding

MICALL1 RAPGEF2 PLEKHN1

1.09e-0424783GO:0070300
GeneOntologyMolecularFunctionsmall GTPase binding

MICALL1 RALBP1 DVL2 PAK2 GOLGA5 FGD6 MLPH

2.59e-04321787GO:0031267
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

3.02e-074803PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

3.02e-074803IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

3.02e-074803IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

3.02e-074803PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

3.02e-074803IPR015753
DomainLRR_8

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

9.26e-05171806PF13855
DomainLeu-rich_rpt_typical-subtyp

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

1.12e-04177806IPR003591
DomainLRR_TYP

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

1.12e-04177806SM00369
DomainLRR

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

2.24e-04201806PS51450
DomainZnf_FYVE_PHD

PIKFYVE PHF2 FGD6 MLPH PRDM14

4.22e-04147805IPR011011
Domain-

CNKSR1 TJP1 DVL2 LRRC7 RAPGEF2

4.63e-041508052.30.42.10
DomainPDZ

CNKSR1 TJP1 DVL2 LRRC7 RAPGEF2

4.77e-04151805PS50106
DomainPDZ

CNKSR1 TJP1 DVL2 LRRC7 RAPGEF2

4.92e-04152805IPR001478
DomainZnf_FYVE

PIKFYVE FGD6 MLPH

5.73e-0438803IPR000306
DomainZF_FYVE

PIKFYVE FGD6 MLPH

6.67e-0440803PS50178
DomainLeu-rich_rpt

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

1.08e-03271806IPR001611
DomainPH

CNKSR1 ABR OBSCN PLEKHN1 FGD6 TECPR1

1.23e-03278806SM00233
DomainPH_DOMAIN

CNKSR1 ABR OBSCN PLEKHN1 FGD6 TECPR1

1.26e-03279806PS50003
DomainPH_domain

CNKSR1 ABR OBSCN PLEKHN1 FGD6 TECPR1

1.28e-03280806IPR001849
Domain-

CNKSR1 ABR OBSCN PLEKHN1 FGD6 TNS3 TECPR1

1.43e-033918072.30.29.30
DomainPH_dom-like

CNKSR1 ABR OBSCN PLEKHN1 FGD6 TNS3 TECPR1

2.32e-03426807IPR011993
DomainLRR_1

LRRC37A LRIG1 LRRC37A3 LRRC37A2 LRRC7

2.50e-03219805PF00560
Domain-

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

2.54e-033218063.80.10.10
DomainL_dom-like

LRRC37A LRIG1 LRRC37A3 LRRC53 LRRC37A2 LRRC7

2.83e-03328806IPR032675
DomainRhoGEF

ABR OBSCN FGD6

3.10e-0368803SM00325
DomainSAM_1

CNKSR1 SCML1 SAMD14

3.10e-0368803PF00536
DomainPDZ

TJP1 DVL2 LRRC7 RAPGEF2

3.16e-03141804PF00595
DomainRasGEFN

RAPGEF2 RGL2

3.27e-0320802SM00229
DomainRhoGEF

ABR OBSCN FGD6

3.37e-0370803PF00621
DomainDH_2

ABR OBSCN FGD6

3.37e-0370803PS50010
DomainDH-domain

ABR OBSCN FGD6

3.51e-0371803IPR000219
Domain-

ABR OBSCN FGD6

3.51e-03718031.20.900.10
DomainRasGEF_N

RAPGEF2 RGL2

3.61e-0321802PF00618
DomainPDZ

TJP1 DVL2 LRRC7 RAPGEF2

3.76e-03148804SM00228
DomainDEP

PIKFYVE DVL2

3.96e-0322802PF00610
DomainRas-like_Gua-exchang_fac_N

RAPGEF2 RGL2

3.96e-0322802IPR000651
DomainDEP

PIKFYVE DVL2

3.96e-0322802PS50186
DomainRASGEF_NTER

RAPGEF2 RGL2

3.96e-0322802PS50212
DomainDEP

PIKFYVE DVL2

3.96e-0322802SM00049
DomainDEP_dom

PIKFYVE DVL2

4.32e-0323802IPR000591
DomainIQ

SCN5A OBSCN MYO15A

5.08e-0381803SM00015
DomainSAM

CNKSR1 SCML1 SAMD14

6.39e-0388803SM00454
DomainIQ_motif_EF-hand-BS

SCN5A OBSCN MYO15A

6.80e-0390803IPR000048
DomainRASGEF_CAT

RAPGEF2 RGL2

6.82e-0329802PS50009
DomainFYVE

PIKFYVE FGD6

6.82e-0329802PF01363
DomainFYVE

PIKFYVE FGD6

6.82e-0329802SM00064
DomainRasGEF

RAPGEF2 RGL2

7.29e-0330802PF00617
Domain-

RAPGEF2 RGL2

7.29e-03308021.10.840.10
DomainRas_GEF_dom

RAPGEF2 RGL2

7.29e-0330802IPR023578
DomainRASGEF_cat_dom

RAPGEF2 RGL2

7.29e-0330802IPR001895
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MICALL1 KIAA1671 TFEB TNK1 NHSL1 NES HIVEP2 MAP2 TJP1 CLMN RAPGEF2 RGL2 FGD6 TNS3 DMTN

1.52e-09861821536931259
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

5.04e-08482322419166
Pubmed

Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK.

NES MAP2 PRKAA1

7.01e-07882337113766
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

1.50e-061082323064749
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

FAM163B KL MAP2 DLGAP4 RTN3 LRRC7 SAMD14 DMTN

1.70e-0634782817114649
Pubmed

Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex.

NES TJP1 RAPGEF2

3.55e-061382327390776
Pubmed

Knockdown of IL4I1 Improved High Glucose-evoked Insulin Resistance in HepG2 Cells by Alleviating Inflammation and Lipotoxicity Through AHR Activation.

AHR IL4I1

5.49e-06282236913096
Pubmed

Prolactin increases expression of cytoskeletal proteins in SK-N-SH cells.

NES MAP2

5.49e-06282225629269
Pubmed

IL4I1-driven AHR signature: a new avenue for cancer therapy.

AHR IL4I1

5.49e-06282233692337
Pubmed

Human Chorionic Gonadotropin-Stimulated Interleukin-4-Induced-1 (IL4I1) Promotes Human Decidualization via Aryl Hydrocarbon Receptor.

AHR IL4I1

5.49e-06282236834576
Pubmed

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.

AHR IL4I1

5.49e-06282232818467
Pubmed

Endogenous Indole Pyruvate Pathway for Tryptophan Metabolism Mediated by IL4I1.

AHR IL4I1

5.49e-06282232866000
Pubmed

High glucose alters the expression of genes involved in proliferation and cell-fate specification of embryonic neural stem cells.

NES MAP2

5.49e-06282216508779
Pubmed

What role for AHR activation in IL4I1-mediated immunosuppression ?

AHR IL4I1

5.49e-06282234026337
Pubmed

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia.

HHEX NUP98

5.49e-06282218388181
Pubmed

[Microtubule-associated protein 2 and nestin expressions in human embryonic and fetal gastric tissues].

NES MAP2

5.49e-06282222985576
Pubmed

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.

NES MAP2 PAK2

5.63e-061582322810622
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KIAA1671 PHF2 HIVEP2 ABR MAP2 TJP1 CLMN NFIB OBSCN RTN3 RPRD2 LRRC7 RAPGEF2 MLPH

9.39e-061489821428611215
Pubmed

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.

NES MAP2 PRKAA1

1.63e-052182319217427
Pubmed

Aryl Hydrocarbon Receptor Defect Attenuates Mitogen-Activated Signaling through Leucine-Rich Repeats and Immunoglobulin-like Domains 1 (LRIG1)-Dependent EGFR Degradation.

LRIG1 AHR

1.64e-05382234576152
Pubmed

Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2.

KL PRKAA1

1.64e-05382227242197
Pubmed

Rab23 Regulates Radial Migration of Projection Neurons via N-cadherin.

NES MAP2

1.64e-05382229420702
Pubmed

Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner.

PIKFYVE PRKAA1

1.64e-05382234107300
Pubmed

The Pluripotency Regulator PRDM14 Requires Hematopoietic Regulator CBFA2T3 to Initiate Leukemia in Mice.

CBFA2T3 PRDM14

1.64e-05382231015254
Pubmed

Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro.

NES MAP2

1.64e-05382221677276
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP2 CLMN DLGAP4 RTN3 LRRC7 DMTN

1.85e-0523182616452087
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPD2 NHSL1 NES LRIG1 MAP2 TJP1 CLMN DLGAP4 PRKAA1 RTN3 LRRC7 RAPGEF2 DMTN

2.91e-051431821337142655
Pubmed

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.

NES MAP2 PAK2

3.16e-052682317875933
Pubmed

AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes.

TFEB PRKAA1

3.28e-05482226944679
Pubmed

Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells.

NES MAP2

3.28e-05482231150727
Pubmed

MHC class I protein is expressed by neurons and neural progenitors in mid-gestation mouse brain.

NES MAP2

3.28e-05482223147111
Pubmed

Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain.

NES MAP2

3.28e-05482212515851
Pubmed

Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells.

NES MAP2

3.28e-05482216914739
Pubmed

Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells.

NES MAP2

3.28e-05482216547973
Pubmed

The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis.

NES MAP2

3.28e-05482219737524
Pubmed

Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain.

NES MAP2

3.28e-05482212752375
Pubmed

Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a.

NES MAP2

3.28e-05482212668607
Pubmed

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

NES MAP2

5.47e-05582210205173
Pubmed

NFIB regulates embryonic development of submandibular glands.

TJP1 NFIB

5.47e-05582225403566
Pubmed

STRADalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice.

NES MAP2

5.47e-05582220424326
Pubmed

Legionella effector AnkX interacts with host nuclear protein PLEKHN1.

MICALL1 PLEKHN1

5.47e-05582229433439
Pubmed

FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation.

NES MAP2

5.47e-05582229799787
Pubmed

Combinatorial roles of the nuclear receptor corepressor in transcription and development.

NES MAP2

5.47e-05582211030619
Pubmed

Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.

NES MAP2

5.47e-05582210096549
Pubmed

C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment.

NES MAP2

5.47e-05582218506028
Pubmed

Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells.

NES MAP2

5.47e-05582223874697
Pubmed

Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.

NES MAP2

5.47e-05582216037066
Pubmed

Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland.

NES MAP2

5.47e-05582220625432
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MICALL1 PIKFYVE SEMA6B TFEB NHSL1 HIVEP2 ABR KANSL1 SCN5A OBSCN RGL2

5.65e-051105821135748872
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

MICALL1 KIAA1671 NHSL1 TJP1 CLMN PAK2 LRRC7 GOLGA5

5.73e-0556582825468996
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

KIAA1671 PHF2 ZC3H4 SCML1 SCN5A DVL2 AHR ASCC3 RAPGEF2 PLEKHN1 SPATC1L

6.17e-051116821131753913
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

KIAA1671 TJP1 ZC3H4 CLMN NUP98 DVL2 PAK2 RPRD2 GOLGA5 NCAPH

6.93e-05934821033916271
Pubmed

SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.

NES TJP1 DVL2

7.83e-053582339366759
Pubmed

Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons.

NES MAP2

8.19e-05682215617678
Pubmed

Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration.

NES MAP2

8.19e-05682217182786
Pubmed

Epiprofin/Sp6 regulates Wnt-BMP signaling and the establishment of cellular junctions during the bell stage of tooth development.

NES TJP1

8.19e-05682222868911
Pubmed

Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex.

NES MAP2

8.19e-05682215504324
Pubmed

Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development.

NES MAP2

8.19e-05682217715063
Pubmed

Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain.

NES MAP2

8.19e-05682216908105
Pubmed

Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium.

NES TJP1

8.19e-05682218582453
Pubmed

Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk.

MAP2 PRKAA1

8.19e-05682230997723
Pubmed

Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium.

NES MAP2

8.19e-05682212453462
Pubmed

Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region.

NES MAP2

8.19e-05682215939089
Pubmed

PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin.

PHF2 NES

8.19e-05682238808662
Pubmed

The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway.

NES TJP1

1.14e-04782227142930
Pubmed

Presenilin-1 regulates neuronal differentiation during neurogenesis.

NES MAP2

1.14e-04782210821758
Pubmed

Neogenin is expressed on neurogenic and gliogenic progenitors in the embryonic and adult central nervous system.

NES MAP2

1.14e-04782217604699
Pubmed

Osterix is dispensable for the development of the mouse olfactory bulb.

NES MAP2

1.14e-04782227449610
Pubmed

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.

HHEX TJP1

1.14e-04782216364283
Pubmed

The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development.

NES MAP2

1.14e-0478227956838
Pubmed

Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.

NES TJP1

1.14e-04782222902295
Pubmed

Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure.

TJP1 DVL2

1.14e-04782225596276
Pubmed

Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice.

NES MAP2

1.14e-0478228863127
Pubmed

Flattop regulates basal body docking and positioning in mono- and multiciliated cells.

TJP1 DVL2

1.14e-04782225296022
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

KIAA1671 NHSL1 SCML1 ASCC3 TNS3

1.40e-0420982536779422
Pubmed

Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.

NES MAP2 TJP1

1.46e-044382327664421
Pubmed

Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse.

AHR MLPH

1.52e-0488227165695
Pubmed

Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair.

NES LRIG1

1.52e-04882234124060
Pubmed

The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells.

NES MAP2

1.52e-04882210627606
Pubmed

Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons.

NES MAP2

1.52e-04882218768805
Pubmed

Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.

NES KL

1.52e-04882228837861
Pubmed

A human MAP kinase interactome.

HIVEP2 KANSL1 NUP98 PAK2 MUC12 RAPGEF2 RGL2

1.54e-0448682720936779
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

PIKFYVE TJP1 DVL2 ASCC3 GOLGA5

1.63e-0421682531519766
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TFEB TJP1 WDCP DVL2 AHR ETV3 RTN3 RPRD2 RAPGEF2 TNS3

1.64e-041038821026673895
Pubmed

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells.

NES TJP1 NFIB

1.78e-044682325182747
Pubmed

Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.

NES TJP1

1.96e-04982212515806
Pubmed

Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain.

NES MAP2

1.96e-04982212798291
Pubmed

Consequence of the loss of Sox2 in the developing brain of the mouse.

NES MAP2

1.96e-04982218638478
Pubmed

Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons.

NES MAP2

1.96e-04982224720729
Pubmed

Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons.

NES MAP2

1.96e-04982222142223
Pubmed

Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice.

NES MAP2

1.96e-04982216571605
Pubmed

Platelet-derived growth factor receptor-alpha in ventricular zone cells and in developing neurons.

NES MAP2

1.96e-04982211414789
Pubmed

Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3.

NES MAP2

1.96e-04982219129405
Pubmed

Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain.

NES TJP1

1.96e-04982226921468
Pubmed

Characterization of TROY-expressing cells in the developing and postnatal CNS: the possible role in neuronal and glial cell development.

NES MAP2

1.96e-04982216820005
Pubmed

EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons.

NES MAP2

1.96e-04982223416450
Pubmed

MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling.

NES MAP2

1.96e-04982225224226
Pubmed

Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis.

NES MAP2

1.96e-04982222898830
Pubmed

Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.

NES MAP2

1.96e-04982228467410
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

TJP1 NUP98 AHR RTN3 ASCC3

2.01e-0422682537839992
InteractionYWHAH interactions

MICALL1 KIAA1671 TFEB TNK1 NHSL1 NES HIVEP2 MAP2 TJP1 CLMN PRKAA1 PAK2 RAPGEF2 RGL2 FGD6 TNS3 DMTN

1.43e-0611028117int:YWHAH
InteractionYWHAB interactions

MICALL1 KIAA1671 TFEB TNK1 NHSL1 MAP2 TJP1 PRKAA1 DVL2 PAK2 RTN3 RAPGEF2 RGL2 FGD6 TNS3 DMTN

2.30e-0610148116int:YWHAB
InteractionYWHAG interactions

MICALL1 KIAA1671 TFEB TNK1 NHSL1 HIVEP2 MAP2 TJP1 CLMN DVL2 PAK2 RTN3 RAPGEF2 RGL2 FGD6 TNS3 DMTN

7.62e-0612488117int:YWHAG
Cytoband17q21.31

LRRC37A KANSL1 LRRC37A2

4.39e-048282317q21.31
Cytoband7p12.3

PKD1L1 TNS3

7.11e-04228227p12.3
GeneFamilyPDZ domain containing

CNKSR1 TJP1 DVL2 LRRC7 RAPGEF2

2.31e-051524151220
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

MAP2 CMYA5 CBFA2T3

3.80e-0529413396
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR OBSCN FGD6

4.49e-0466413722
GeneFamilySterile alpha motif domain containing

CNKSR1 SCML1 SAMD14

1.04e-0388413760
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

CNKSR1 ABR PLEKHN1 FGD6

1.19e-03206414682
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PIKFYVE FGD6

2.24e-033141281
CoexpressionPURWIN_MEWO_SOX10_TARGETS

NHSL1 NES ABR NFIB RAPGEF2

9.91e-0692815M48228
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LRIG1 MAP2 NFIB LRRC7 PLG TNS3

1.24e-061868264d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 TRIM41 LRRC37A2 FAM217B PAK2 SMPD2

1.59e-0619482688db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 TRIM41 LRRC37A2 FAM217B PAK2 SMPD2

1.59e-06194826a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MICALL1 TNK1 LRRC37A2 SMPD2 CMYA5 MYO15A

1.89e-062008260f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HHEX TJP1 NFIB AHR RGL2 IL4I1

1.89e-062008263585484c7e24e941708bee471ca607d8ccee74e6
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 PGGHG TRIM41 LRRC37A2 PAK2

1.52e-05169825665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 PGGHG TRIM41 LRRC37A2 PAK2

1.52e-051698256614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

GPD2 NOP9 LRIG1 SAMD14 IL4I1

1.61e-051718250d14bc9688c427ba2265984987dc3eea195b19eb
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

SEMA6B NES KL LRRC37A3 NFIB

1.90e-05177825f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

NES HIVEP2 LRRC37A3 DLGAP4 TNS3

1.95e-05178825edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPD2 HIVEP2 NTAN1 DLGAP4 FGD6

2.23e-0518382591079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KIAA1671 TJP1 NFIB CMYA5 DMTN

2.35e-05185825d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL AHR

2.74e-05191825edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL IL4I1

2.74e-05191825e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFIB RALBP1 RTN3 CMYA5 VWA5B1

2.95e-0519482569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RALBP1 AHR CMYA5 MLPH VWA5B1

3.02e-051958253d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCelltumor_Lung-Endothelial_cells-Tip-like_ECs|tumor_Lung / Location, Cell class and cell subclass

NES KL TJP1 NFIB SAMD14

3.18e-05197825353b76ca3e2aa4b8f51396e7121c4baa114083a0
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL1 KANSL1 STAG1 LRRC37A3 RAPGEF2

3.25e-051988251996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

NHSL1 HIVEP2 MAP2 NFIB DLGAP4

3.41e-0520082584e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

KIAA1671 NHSL1 ABR LRIG1 FGD6

3.41e-05200825941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NES TJP1 AHR RGL2 IL4I1

3.41e-0520082579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NES KL TJP1 DLGAP4 AHR

3.41e-0520082566f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NES KL TJP1 DLGAP4 AHR

3.41e-05200825b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HHEX TJP1 NFIB AHR RGL2

3.41e-0520082558a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HHEX TJP1 NFIB AHR RGL2

3.41e-05200825b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RALBP1 AHR PCARE MLPH

1.34e-04141824091b5b72811db5fca2314f4a79d467566920e257
ToppCellPND07-Immune-Immune_Myeloid-DC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 CBFA2T3 PLEKHN1 IL4I1

1.57e-04147824bbc52cbea37a38058436e3fc6fc0777f83404524
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

WDCP PLEKHN1 NCAPH IL4I1

1.65e-041498242a7f71da51c85e04de2123164914122480e60d66
ToppCellsevere_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

TNK1 CNKSR1 OBSCN SPATC1L

1.88e-0415482465ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MED16 KEL LRRC7 NCAPH

1.92e-041558244559e3011514041b65c17ae4ede29da202bce14c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES CLMN WDCP CBFA2T3

2.02e-04157824f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HHEX KEL CBFA2T3 DMTN

2.07e-04158824944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RALBP1 SCML1 RTN3 CMYA5

2.17e-041608247064af50fc10e3ea03badf415306222b74db0f95
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 CBFA2T3 PLEKHN1 IL4I1

2.17e-041608247db30647b596f0c419087e6fabb9b99dcd5bddd4
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETV3 CBFA2T3 PLEKHN1 IL4I1

2.17e-0416082401f22cdb2a2f73776b7f91746e95c1850df94235
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 CLMN PSORS1C2 SAMD14

2.28e-041628243dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 CLMN PSORS1C2 SAMD14

2.28e-041628240a7138266054ea5954649c8b61ef93905d56b068
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 CLMN PSORS1C2 SAMD14

2.28e-0416282425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellB_cells-ABCs|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PIKFYVE TFEB HHEX CBFA2T3

2.39e-04164824f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MICALL1 AHR CBFA2T3 DMTN

2.56e-04167824b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SCML1 AHR IL4I1 FGD6

2.61e-04168824d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLEKHN1 NCAPH IL4I1 DMTN

2.86e-04172824d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHEX AHR ETV3 CBFA2T3

2.99e-04174824c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZC3H4 RAPGEF2 GOLGA5 PLEKHN1

3.05e-04175824f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES STAG1 PAK2 ASCC3

3.26e-0417882401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV3 KEL IL4I1

3.31e-04738233ac392ac46ad577c7d2c2b5e6a0a96ceb613097b
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV3 KEL IL4I1

3.31e-04738231bd6ff9659efc43b0a596da50e325bde2f0ba8f7
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AHR RAPGEF2 PLEKHN1 IL4I1

3.33e-04179824d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIKFYVE HHEX SCML1 CBFA2T3

3.33e-04179824a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TJP1 NFIB CMYA5 DMTN

3.33e-0417982499777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 ETV3 PLEKHN1 IL4I1

3.33e-04179824d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B NES FAM217B CBFA2T3

3.40e-04180824f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B NES FAM217B CBFA2T3

3.40e-0418082453db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B NES FAM217B CBFA2T3

3.40e-0418082428bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

ETV3 SAMD14 IL4I1 PRDM14

3.47e-04181824982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

ETV3 SAMD14 IL4I1 PRDM14

3.47e-041818246252184ef098b911df50be4fe1b5565849a5b6b8
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NES CLMN NFIB CBFA2T3

3.54e-04182824e67f3234165199085c793915ebb1f9bbd845e933
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

HHEX TJP1 AHR NCAPH

3.54e-04182824ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

KIAA1671 HHEX TJP1 AHR

3.54e-04182824fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NES HHEX ALG1L2 TECPR1

3.62e-04183824ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA6B NES HHEX KL

3.62e-04183824a644258ba90acc62d571623e429d72ffc4b69203
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 LRIG1 PGGHG TNS3

3.85e-0418682473cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPD2 TFEB MAP2 VWA5B1

3.85e-04186824a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIKFYVE TFEB HHEX CBFA2T3

3.85e-04186824fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TJP1 CLMN OBSCN CBFA2T3

3.92e-0418782486250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRIG1 MAP2 SCN5A ANKRD53

3.92e-0418782469b47f00598d647e2a99427ebddf42c339428e47
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL

3.92e-0418782429b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SEMA6B HHEX TECPR1

3.92e-041878240ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

NES TJP1 CLMN CBFA2T3

3.92e-04187824406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 HHEX KL AHR

3.92e-04187824106f50ad85a92403037214f0e94702230284837f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES TJP1 PCARE CMYA5

3.92e-0418782424c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX TECPR1

3.92e-04187824a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

SCN5A OBSCN LRRC7 CMYA5

4.00e-041888246d249fe92d51a19da19ec14bb2262d394255d577
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL

4.00e-04188824b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

LRRC37A3 DLGAP4 FAM217B TNS3

4.00e-0418882414bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPD2 TFEB MAP2 VWA5B1

4.00e-04188824e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

PGGHG MAP2 TJP1 DMTN

4.00e-04188824be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellNS-moderate-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIKFYVE TFEB HHEX CBFA2T3

4.00e-04188824e9ed34cfea1d93eaa8e63d5b5dbb64f1520d9c4c
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TJP1 CLMN OBSCN CBFA2T3

4.00e-04188824ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NFIB KEL SAMD14 DMTN

4.00e-04188824c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL

4.09e-04189824033a2be8bbb7bfb437e6f1657b6ca02070c74aa8
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 LRIG1 PGGHG TNS3

4.17e-0419082478cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIKFYVE TJP1 SMPD2 CBFA2T3

4.17e-04190824ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

MAP2 CLMN RAPGEF2 CBFA2T3

4.17e-04190824a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL1 LRIG1 PGGHG TNS3

4.17e-04190824e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SEMA6B HHEX KL

4.17e-041908247ba2be2630183df86de21689289a8620a4cd507e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFIB RALBP1 CMYA5 VWA5B1

4.25e-041918243e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 NES ABR MAP2

4.25e-04191824b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTAN1 TJP1 NFIB DMTN

4.25e-04191824361b123c8289015206d5e706ab2c615d9a724179
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 SCN5A OBSCN CMYA5

4.25e-04191824543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

KIAA1671 HHEX TJP1 AHR

4.25e-0419182444c596984c6196f6014e0e405dbe5560841e54ff
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

SCN5A OBSCN LRRC7 CMYA5

4.25e-041918245d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

PIKFYVE TFEB HHEX CBFA2T3

4.25e-04191824c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

KIAA1671 HHEX TJP1 AHR

4.25e-04191824e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 SCN5A OBSCN CMYA5

4.25e-041918249d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellfacs-Thymus-Epithelium-24m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SEMA6B NES NFIB

4.34e-0419282439afea574725ce0c67afdd79facdb34f819a828d
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 KL LRIG1 CBFA2T3

4.34e-0419282414a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SEMA6B NES NFIB

4.34e-04192824597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SEMA6B NES NFIB

4.34e-04192824bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES HHEX TJP1 AHR

4.34e-04192824e4dd24aefdf13cd4206714f02fde2288f3173ffc
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MICALL1 PHF2 ZC3H4 NFIB RPRD2 CBFA2T3 TNS3

2.12e-061688073868_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

PHF2 STAG1 ZC3H4 NFIB RPRD2 CBFA2T3 TNS3

2.48e-061728071072_DN
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

HIVEP2 STAG1 NFIB NUP98 RAPGEF2 NCAPH TNS3

2.68e-061748077530_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

MICALL1 PHF2 STAG1 ZC3H4 NFIB CBFA2T3 TNS3

3.00e-061778071645_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 STAG1 ZC3H4 NFIB RPRD2 CBFA2T3 MLPH

3.12e-061788076276_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

MICALL1 PHF2 NFIB RPRD2 CBFA2T3 TNS3

2.92e-051698065231_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

PHF2 STAG1 ZC3H4 NFIB RPRD2 CBFA2T3

3.02e-051708061050_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MICALL1 PHF2 ZC3H4 NFIB RPRD2 CBFA2T3

3.22e-051728063428_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

PHF2 STAG1 ZC3H4 NFIB RPRD2 CBFA2T3

3.55e-051758061058_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 NFIB RPRD2 CBFA2T3 MLPH TNS3

3.67e-051768066932_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

PHF2 STAG1 ZC3H4 NFIB RPRD2 CBFA2T3

3.78e-051778066434_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 STAG1 NFIB RPRD2 CBFA2T3 TNS3

3.78e-051778065308_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A

MICALL1 PHF2 STAG1 ZC3H4 RPRD2 CBFA2T3

4.03e-051798061175_DN
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

MICALL1 PHF2 STAG1 NFIB CBFA2T3 TNS3

4.03e-05179806332_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MICALL1 STAG1 ZC3H4 NFIB CBFA2T3 MLPH

4.29e-051818067005_DN
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

MICALL1 NFIB NUP98 DVL2 SMPD2 DMTN

5.95e-051928066044_DN
DrugBrinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A

GPD2 TNK1 CNKSR1 MED16 SMPD2 DMTN

6.67e-051968065016_DN
DrugAzaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TNK1 NES CNKSR1 DLGAP4 DVL2 RAPGEF2

6.86e-051978067231_DN
DrugZalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A

MICALL1 GPD2 WDCP NUP98 RAPGEF2 DMTN

6.86e-051978067352_DN
DrugCinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

GPD2 TNK1 HHEX NFIB DVL2 DMTN

7.06e-051988063175_DN
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

GPD2 CNKSR1 HIVEP2 NFIB SMPD2 FGD6

7.26e-051998065701_DN
Drug1,2,3,4,7,8-hexachlorodibenzodioxin

PRKAA1 AHR

7.28e-054802ctd:C078219
DiseaseMalignant neoplasm of breast

MICALL1 HHEX NOP9 LRRC37A WDCP PRKAA1 LRRC37A2 NUP98 OBSCN FAM217B AHR LRRC7

2.11e-0510747712C0006142
Diseasebrain ischemia (biomarker_via_orthology)

NES MAP2 TJP1 SCN5A

1.50e-04102774DOID:2316 (biomarker_via_orthology)
DiseaseMental Retardation, Psychosocial

CNKSR1 KANSL1 STAG1 ASCC3

4.89e-04139774C0025363
DiseaseProfound Mental Retardation

CNKSR1 KANSL1 STAG1 ASCC3

4.89e-04139774C0020796
DiseaseMental deficiency

CNKSR1 KANSL1 STAG1 ASCC3

4.89e-04139774C0917816
Diseasenoggin measurement

HHEX HIVEP2

1.00e-0318772EFO_0021995
Diseasecoronary artery disease

PHF2 HIVEP2 STAG1 NFIB RPRD2 LRRC7 PLG RAPGEF2 FGD6 TNS3

1.06e-0311947710EFO_0001645
DiseaseIntellectual Disability

CNKSR1 HIVEP2 KANSL1 STAG1 NFIB ASCC3

1.12e-03447776C3714756
Diseasebasal cell carcinoma

DLGAP4 AHR MYO15A TNS3

1.53e-03189774EFO_0004193
Diseasereticulocyte measurement

PIKFYVE KANSL1 MED16 ZC3H4 PRKAA1 PAK2 KEL CBFA2T3 TNS3

1.66e-031053779EFO_0010700
Diseasehemoglobin A1 measurement

HHEX KL LRIG1 ZC3H4 AHR PAK2

2.40e-03520776EFO_0007629
Diseasecortical surface area measurement

NHSL1 ABR KANSL1 LRIG1 STAG1 MAP2 TJP1 NFIB RALBP1 FGD6

2.55e-0313457710EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
EESEASPQVHPFPDH

ABR

361

Q12979
HHPSEARPFPDLTSS

AHR

831

P35869
STHSPFRARSEPEDP

ALG1L2

36

C9J202
ASSRFHFPPLDTHSP

ETV3

146

P41162
DSRPRHLSDSLDPPH

DLGAP4

6

Q9Y2H0
HLSDSLDPPHEPLFA

DLGAP4

11

Q9Y2H0
SRPPSFHPNVSSSHE

DVL2

131

O14641
LPPTSSPSEHRRVEH

RALBP1

6

Q15311
DSSPRLSTFPQHHHP

NFIB

331

O00712
PEPTHLHADSRDCPT

CDRT4

116

Q8N9R6
HPDPTPEHDFSSFLE

ANKRD53

411

Q8N9V6
RSEPAPDSHPHLSPE

NOP9

46

Q86U38
LHHPPDRTSDSTPDP

NUP98

1761

P52948
SSHSSHFPRESPHAP

LRRC37A3

61

O60309
HFPRESPHAPTLPAD

LRRC37A3

66

O60309
DTPTDVTHHPIPSEE

GPD2

356

P43304
FSSLVPEDSPHVGHR

KIAA1671

961

Q9BY89
SSHSSHFPRESPHAP

LRRC37A2

61

A6NM11
HFPRESPHAPTLPAD

LRRC37A2

66

A6NM11
SSHSSHFPRESPHAP

LRRC37A

61

A6NMS7
HFPRESPHAPTLPAD

LRRC37A

66

A6NMS7
PRDASHFPEPDTHSV

LRIG1

876

Q96JA1
HFPEPDTHSVACRQP

LRIG1

881

Q96JA1
STHRHTPETEVPPSN

LRRC7

826

Q96NW7
LPFEDEAPFHHSGSR

MYO15A

206

Q9UKN7
EPTPIHPAFSHHSAA

HHEX

71

Q03014
HPVENASVPRPSSHF

GOLGA5

96

Q8TBA6
PQPTPTDAEHRHSHS

LRRC53

841

A6NM62
DSDDDHSRNHSPSPP

NHSL1

1376

Q5SYE7
EIHPSHYAFETSPRP

FAM217B

256

Q9NTX9
EDHASLAPPLSPDHS

NES

461

P48681
HPVLAFPDDVPTSLH

KANSL1

666

Q7Z3B3
HASRLSHSEPPSATP

MICALL1

491

Q8N3F8
EDPTTFAAHSLPSDP

PGGHG

6

Q32M88
PEEDASHAHPEPATA

PSMB11

256

A5LHX3
ATRPPSFTPHTHRED

CBFA2T3

91

O75081
SFTPHTHREDGPATL

CBFA2T3

96

O75081
SPRTPRSLDHLHPED

MED16

861

Q9Y2X0
SHSLEHDSPSTPRPS

OBSCN

6961

Q5VST9
FDPHRGTPLSDHEAL

SMPD2

261

O60906
RPEISPPSDFEHTIH

PAK2

71

Q13177
DLPRSPTSPSHLTHF

PIKFYVE

16

Q9Y2I7
SHEGLVTDPHSPARF

EEF1AKMT4-ECE2

836

P0DPD8
HPTTSPTAASRDVHP

LINC00482

31

Q8N8I6
EPDFAVHSHLPPLHS

FAM163B

46

P0C2L3
PDLVVASEHSFPPHT

CMYA5

846

Q8N3K9
DTFTHHPLAPPGDSR

KL

91

Q9UEF7
PHFHHPETSRPDSNI

DMTN

126

Q08495
FNSTFEHHLPPSPLE

RPRD2

1186

Q5VT52
RSQPTHSPDPHLSDF

PKD1L1

1056

Q8TDX9
SHPEEQPTSISPSRH

MLPH

256

Q9BV36
HSRPQSSPADRESPF

PCARE

511

A6NGG8
SPSHDLAKEEGSHPP

IL4I1

536

Q96RQ9
VHCDRPSIPASFPEH

RTN3

151

O95197
LESSPSLHSPADPSH

RGL2

586

O15211
ELESAHHPFTAPHPS

DARS2

496

Q6PI48
SRTPSPVHPSDFSEH

SCML1

176

Q9UN30
SPDPCQPHSHDFLTD

TRIM41

401

Q8WV44
QPPSPFHHLDFSHSL

TFEB

386

P19484
PDAPDHTSETSHSPL

PLEKHN1

441

Q494U1
EPPPESHSSSLADHE

PHF2

1011

O75151
HVPREVPPFLSSSHE

PRDM14

106

Q9GZV8
SHSEDLADFPPSPDR

SCN5A

1996

Q14524
SSDEFLDEPLPPVHH

SAMD14

311

Q8IZD0
SPLAEPPHFVEHIRS

NTAN1

256

Q96AB6
PFHSHELSLAEPPDS

TNS3

996

Q68CZ2
SPHRPRFSPATHPSE

PLG

131

P00747
AFLSPPEPHSHRGTD

SPATC1L

116

Q9H0A9
SPPDSFLDDHHLTRP

PRKAA1

356

Q13131
PIESNPHSFDSPHTK

ASCC3

1876

Q8N3C0
ARHDEESHSLSPPGE

CLMN

516

Q96JQ2
GHPHSASSPSERVFP

NCAPH

21

Q15003
QSPHSLPSDPEEHSH

CNKSR1

691

Q969H4
ITDFPEGHSHPARKP

RAPGEF2

1411

Q9Y4G8
RASHGDFPLTPHASP

SEMA6B

781

Q9H3T3
FVSEPSPDLEAHEHP

TECPR1

741

Q7Z6L1
SPSPSSFEKVPDHHS

FGD6

226

Q6ZV73
PESEHGSEPDFLHNP

STAG1

1136

Q8WVM7
HLFPEHPLEPDSFSE

ZC3H4

731

Q9UPT8
SAPLTEASAHSHPPE

MAP2

16

P11137
DSHPSPHFPRDSGIH

nan

6

Q6ZRN7
PDQRSEPSDHSRHSP

TJP1

316

Q07157
APHPADRPSFSHLEG

TNK1

361

Q13470
RHSSTPDHTSTLEPP

WDCP

526

Q9H6R7
EPSSSPRDFSPSSHH

HIVEP2

2031

P31629
SPGDLEPSHHPSAFE

VWA5B1

766

Q5TIE3
HPSHPPAEDREEAGS

PSORS1C2

26

Q9UIG4
SPQDSHDTHSPPHLR

KEL

686

P23276
SHSRPGPTHTIAFPD

MUC12

311

Q9UKN1