Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 TAS2R42 ADRA1D CELSR1 TAS2R14 CELSR3 CELSR2 FZD10 TAS2R40 CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	5.50e-10	884	141	26	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51A4 OR51A2 ABCA1 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GFRA2 GPR146 MST1R OR2L2 TAS2R42 ADRA1D CELSR1 TAS2R14 CELSR3 CELSR2 FZD10 TAS2R40 CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	6.21e-08	1353	141	29	GO:0004888
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC43A2 ANO9 ABCA1 PIEZO1 PKD1L1 SLC22A11 CYB561D2 SLC17A4 SLCO4A1 MFSD4A TMC4 SLC4A3 SLC38A1 CNNM4 ABCG4 SLC30A5 CLCN4 SLC16A6 ABCA5 LRRC26 NIPA2 SLC25A29 SLC39A7 VDAC1	2.57e-06	1180	141	24	GO:0022857
GeneOntologyMolecularFunction	transporter activity	SLC43A2 ANO9 ABCA1 PIEZO1 PKD1L1 SLC22A11 CYB561D2 SLC17A4 SLCO4A1 MFSD4A TMC4 SLC4A3 SLC38A1 CNNM4 ABCG4 SLC30A5 CLCN4 SLC16A6 ABCA5 LRRC26 NIPA2 SLC25A29 SLC39A7 VDAC1	1.15e-05	1289	141	24	GO:0005215
GeneOntologyMolecularFunction	protein-hormone receptor activity	LGR4 LGR5 CMKLR1	4.81e-04	22	141	3	GO:0016500
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCA1 SLC22A11 CYB561D2 SLC17A4 SLCO4A1 SLC4A3 SLC38A1 ABCG4 SLC30A5 CLCN4 ABCA5	5.83e-04	477	141	11	GO:0022804
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR51A4 OR51A2 ABCA1 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 ADCY9 GPR146 OR2L2 TAS2R42 ADRA1D CELSR1 TAS2R14 CELSR3 CELSR2 FZD10 TAS2R40 CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	2.18e-07	1395	141	28	GO:0007186
Domain	GPCR_Rhodpsn_7TM	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 TAS2R42 ADRA1D CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	1.96e-07	670	143	20	IPR017452
Domain	G_PROTEIN_RECEP_F1_2	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 TAS2R42 ADRA1D CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	3.20e-07	691	143	20	PS50262
Domain	GPCR_Rhodpsn	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 TAS2R42 ADRA1D CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	3.28e-07	692	143	20	IPR000276
Domain	7tm_1	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 ADRA1D CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	1.03e-06	677	143	19	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51A4 OR51A2 OXER1 GPR17 FPR1 LGR4 OR2AG2 OR2M3 LGR5 OR2L13 GPR146 OR2L2 ADRA1D CMKLR1 OR4K15 HRH3 S1PR4 OR10A5 OR2AG1	1.23e-06	685	143	19	PS00237
Domain	LamG	COL15A1 CELSR1 CNTNAP5 CELSR3 CELSR2	2.09e-05	44	143	5	SM00282
Domain	GAIN_dom_N	CELSR1 CELSR3 CELSR2	6.93e-05	11	143	3	IPR032471
Domain	GAIN	CELSR1 CELSR3 CELSR2	6.93e-05	11	143	3	PF16489
Domain	Laminin_G	COL15A1 CELSR1 CNTNAP5 CELSR3 CELSR2	8.11e-05	58	143	5	IPR001791
Domain	GPS	PKD1L1 CELSR1 CELSR3 CELSR2	1.60e-04	36	143	4	PS50221
Domain	GPS	PKD1L1 CELSR1 CELSR3 CELSR2	1.79e-04	37	143	4	IPR000203
Domain	MFS	SLC43A2 SLC22A11 SLC17A4 SLCO4A1 MFSD4A SLC16A6	1.83e-04	108	143	6	PS50850
Domain	LAM_G_DOMAIN	CELSR1 CNTNAP5 CELSR3 CELSR2	1.99e-04	38	143	4	PS50025
Domain	Laminin_G_2	CELSR1 CNTNAP5 CELSR3 CELSR2	2.43e-04	40	143	4	PF02210
Domain	MFS_1	SLC43A2 SLC22A11 SLC17A4 MFSD4A SLC16A6	3.11e-04	77	143	5	PF07690
Domain	MFS	SLC43A2 SLC22A11 SLC17A4 MFSD4A SLC16A6	3.11e-04	77	143	5	IPR011701
Domain	RDM_domain_RFPL	RFPL1 RFPL2	5.73e-04	5	143	2	IPR022723
Domain	RDM	RFPL1 RFPL2	5.73e-04	5	143	2	PF11002
Domain	MFS_dom	SLC43A2 SLC22A11 SLC17A4 SLCO4A1 MFSD4A SLC16A6	5.83e-04	134	143	6	IPR020846
Domain	Gphrmn_rcpt_fam	LGR4 LGR5	8.56e-04	6	143	2	IPR002131
Domain	HormR	CELSR1 CELSR3 CELSR2	8.93e-04	25	143	3	SM00008
Domain	LRRNT	LGR4 LGR5 IGSF10 LRRC26 LGI1	9.41e-04	98	143	5	IPR000372
Domain	LRRNT	LGR4 LGR5 IGSF10 LRRC26 LGI1	9.41e-04	98	143	5	SM00013
Domain	TAS2R	TAS2R42 TAS2R14 TAS2R40	1.00e-03	26	143	3	PF05296
Domain	T2R	TAS2R42 TAS2R14 TAS2R40	1.00e-03	26	143	3	IPR007960
Domain	GPCR_2_secretin-like	CELSR1 CELSR3 CELSR2 FZD10	1.15e-03	60	143	4	IPR000832
Domain	GPCR_2-like	CELSR1 CELSR3 CELSR2 FZD10	1.15e-03	60	143	4	IPR017981
Domain	RPEL	PHACTR4 MYOCD	1.19e-03	7	143	2	PS51073
Domain	RPEL	PHACTR4 MYOCD	1.19e-03	7	143	2	SM00707
Domain	RPEL	PHACTR4 MYOCD	1.19e-03	7	143	2	PF02755
Domain	RPEL_repeat	PHACTR4 MYOCD	1.19e-03	7	143	2	IPR004018
Domain	G_PROTEIN_RECEP_F2_4	CELSR1 CELSR3 CELSR2 FZD10	1.23e-03	61	143	4	PS50261
Domain	HRM	CELSR1 CELSR3 CELSR2	1.25e-03	28	143	3	PF02793
Domain	ConA-like_dom	COL15A1 RFPL1 CELSR1 CNTNAP5 CELSR3 CELSR2 RFPL2	1.51e-03	219	143	7	IPR013320
Domain	EGF_LAM_2	CELSR1 CELSR3 CELSR2	1.53e-03	30	143	3	PS50027
Domain	EGF_LAM_1	CELSR1 CELSR3 CELSR2	1.53e-03	30	143	3	PS01248
Domain	WD40_repeat_dom	ARPC1A AMBRA1 LRRK1 EDC4 WDHD1 TENM3 WDR90 DCAF4L1	2.08e-03	297	143	8	IPR017986
Domain	GPS	CELSR1 CELSR3 CELSR2	2.21e-03	34	143	3	SM00303
Domain	EGF_Lam	CELSR1 CELSR3 CELSR2	2.40e-03	35	143	3	SM00180
Domain	GPS	CELSR1 CELSR3 CELSR2	2.40e-03	35	143	3	PF01825
Domain	Laminin_EGF	CELSR1 CELSR3 CELSR2	2.40e-03	35	143	3	PF00053
Domain	LRR_TYP	LGR4 LRRK1 LGR5 IGSF10 LRRC26 LGI1	2.44e-03	177	143	6	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LGR4 LRRK1 LGR5 IGSF10 LRRC26 LGI1	2.44e-03	177	143	6	IPR003591
Domain	ThiF_NAD_FAD-bd	ATG7 UBA1	2.52e-03	10	143	2	IPR000594
Domain	ThiF	ATG7 UBA1	2.52e-03	10	143	2	PF00899
Domain	Laminin_EGF	CELSR1 CELSR3 CELSR2	3.05e-03	38	143	3	IPR002049
Domain	Olfact_rcpt	OR51A4 OR51A2 OR2AG2 OR2M3 OR2L13 OR2L2 OR4K15 OR10A5 OR2AG1	3.31e-03	393	143	9	IPR000725
Domain	GPCR_2_extracellular_dom	CELSR1 CELSR3 CELSR2	3.53e-03	40	143	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	CELSR1 CELSR3 CELSR2	3.53e-03	40	143	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	CELSR1 CELSR3 CELSR2	3.53e-03	40	143	3	PS50227
Domain	ABC_A	ABCA1 ABCA5	3.65e-03	12	143	2	IPR026082
Domain	ABC_transporter_CS	ABCA1 ABCG4 ABCA5	4.06e-03	42	143	3	IPR017871
Domain	-	ARPC1A AMBRA1 EDC4 MST1R NBAS WDHD1 WDR90 DCAF4L1	4.17e-03	333	143	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	ARPC1A AMBRA1 EDC4 MST1R NBAS WDHD1 WDR90 DCAF4L1	4.32e-03	335	143	8	IPR015943
Domain	MS4A	MS4A14 MS4A6A	4.99e-03	14	143	2	IPR030417
Domain	AAA	RAD51B ABCA1 DNAH7 ABCG4 ABCA5	5.04e-03	144	143	5	SM00382
Domain	AAA+_ATPase	RAD51B ABCA1 DNAH7 ABCG4 ABCA5	5.04e-03	144	143	5	IPR003593
Domain	WD_REPEATS_1	ARPC1A AMBRA1 EDC4 NBAS WDHD1 WDR90 DCAF4L1	5.64e-03	278	143	7	PS00678
Domain	WD_REPEATS_2	ARPC1A AMBRA1 EDC4 NBAS WDHD1 WDR90 DCAF4L1	5.75e-03	279	143	7	PS50082
Domain	WD_REPEATS_REGION	ARPC1A AMBRA1 EDC4 NBAS WDHD1 WDR90 DCAF4L1	5.75e-03	279	143	7	PS50294
Domain	ABC_tran	ABCA1 ABCG4 ABCA5	5.91e-03	48	143	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA1 ABCG4 ABCA5	5.91e-03	48	143	3	PS50893
Domain	-	CELSR1 CNTNAP5 CELSR3 CELSR2	6.12e-03	95	143	4	2.60.120.200
Domain	ABC_TRANSPORTER_1	ABCA1 ABCG4 ABCA5	6.26e-03	49	143	3	PS00211
Domain	7tm_2	CELSR1 CELSR3 CELSR2	6.62e-03	50	143	3	PF00002
Domain	ABC_transporter-like	ABCA1 ABCG4 ABCA5	6.62e-03	50	143	3	IPR003439
Domain	G_PROTEIN_RECEP_F2_2	CELSR1 CELSR3 CELSR2	6.62e-03	50	143	3	PS00650
Domain	ASX_HYDROXYL	CELSR1 CELSR3 CELSR2 HMCN1	7.33e-03	100	143	4	PS00010
Pathway	WP_GPCRS_NONODORANT	GPR17 FPR1 ADRA1D CELSR1 TAS2R14 CELSR3 CELSR2 TAS2R40 HRH3 S1PR4	2.05e-05	266	101	10	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	OXER1 GPR17 FPR1 TAS2R42 SAA1 ADRA1D TAS2R14 FZD10 KEL TAS2R40 CMKLR1 HRH3 S1PR4	2.56e-05	463	101	13	M507
Pathway	WP_GPCRS_OTHER	GPR17 ADRA1D CELSR1 CELSR3 CELSR2 OR10A5	5.37e-05	93	101	6	M39629
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC43A2 ANO9 ABCA1 SLC22A11 SLCO4A1 SLC4A3 ADCY9 SLC38A1 ABCG4 SLC30A5 CLCN4 ABCA5 NIPA2 SLC25A29 SLC39A7 VDAC1	6.46e-05	736	101	16	M27287
Pathway	REACTOME_SIGNALING_BY_GPCR	OXER1 GPR17 RASGRF2 FPR1 ADCY9 TAS2R42 SAA1 ADRA1D TAS2R14 FZD10 KEL TAS2R40 CMKLR1 HRH3 S1PR4	1.36e-04	702	101	15	M746
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	STK36 ERCC2 MYO7A LONRF1 PIEZO1 ZBTB4 CYB561D2 SLCO4A1 AMBRA1 LRRK1 EDC4 ADCY9 TYK2 PCNX2 MST1R CELSR1 CELSR3 CELSR2 MAD1L1 PIGW MICAL3 WDR90 DOCK6	2.56e-10	1105	146	23	35748872
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR3 CELSR2	7.25e-08	3	146	3	11677057
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR3 CELSR2	2.89e-07	4	146	3	37224017
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR3 CELSR2	2.89e-07	4	146	3	11850187
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR1 CELSR3 CELSR2	2.51e-06	7	146	3	17937400
Pubmed	Genomic analysis of orthologous mouse and human olfactory receptor loci.	OR2AG2 OR10A5 OR2AG1	5.98e-06	9	146	3	11416212
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SLC43A2 CMTM3 GPR17 PRSS16 RHBDD2 SLCO4A1 MFSD4A MBOAT2 SLC4A3 GPR146 TM7SF2 TTI1 NIPA2	8.34e-06	697	146	13	28298427
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CELSR3 CELSR2	1.17e-05	11	146	3	25024228
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL15A1 TM9SF1 PIEZO1 LGR4 MBOAT2 SLC38A1 IGSF10 MST1R CELSR1 UBA1 CELSR3 CELSR2 TENM3 SVIL TTI1 SLC39A7 CA5A	1.27e-05	1201	146	17	35696571
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 CELSR3 CELSR2	1.55e-05	12	146	3	11891983
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR3 CELSR2	1.55e-05	12	146	3	20631168
Pubmed	Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.	OXER1 GPR17 FPR1 SAA1 S1PR4	1.66e-05	75	146	5	2834384
Pubmed	A quantitative model of the switch cycle of an archaeal flagellar motor and its sensory control.	DLG5 ABCA1	1.75e-05	2	146	2	16192281
Pubmed	Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.	LGR4 LGR5	1.75e-05	2	146	2	36410420
Pubmed	Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9.	CELSR3 CELSR2	1.75e-05	2	146	2	10790539
Pubmed	Serum amyloid A is a chemotactic agonist at FPR2, a low-affinity N-formylpeptide receptor on mouse neutrophils.	FPR1 SAA1	1.75e-05	2	146	2	10753626
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	1.75e-05	2	146	2	23292348
Pubmed	Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.	LGR4 LGR5	1.75e-05	2	146	2	9849958
Pubmed	Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.	LGR5 SLC39A7	1.75e-05	2	146	2	27736879
Pubmed	AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through an ATG7-independent pathway.	ATG7 AMBRA1	1.75e-05	2	146	2	28789945
Pubmed	Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells.	ABCA1 MYOCD	1.75e-05	2	146	2	33035679
Pubmed	Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.	ATG7 AMBRA1	1.75e-05	2	146	2	27390127
Pubmed	Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia.	ABCA1 ABCA5	1.75e-05	2	146	2	32687853
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	ABCA1 EDC4 CELSR2 DOCK6	2.19e-05	39	146	4	21347282
Pubmed	Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.	CELSR1 CELSR3 CELSR2	2.55e-05	14	146	3	39225402
Pubmed	A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.	MYO7A CELSR1 CELSR3	2.55e-05	14	146	3	29784671
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR1 CELSR3 CELSR2	3.18e-05	15	146	3	20473291
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	CELSR1 CELSR3 CELSR2 FZD10	4.62e-05	47	146	4	33141892
Pubmed	LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.	MYO7A LGR4 LGR5	4.72e-05	17	146	3	27559308
Pubmed	Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.	LGR4 LGR5	5.24e-05	3	146	2	28634819
Pubmed	Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.	ATG7 LGR5	5.24e-05	3	146	2	32371487
Pubmed	Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.	RFPL1 RFPL2	5.24e-05	3	146	2	18656177
Pubmed	ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane.	ABCA1 ABCG4	5.24e-05	3	146	2	25302608
Pubmed	Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts.	LGR4 LGR5	5.24e-05	3	146	2	28777797
Pubmed	Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases.	LGR4 LGR5	5.24e-05	3	146	2	33262293
Pubmed	Activation of formyl peptide receptor like-1 by serum amyloid A induces CCL2 production in human umbilical vein endothelial cells.	FPR1 SAA1	5.24e-05	3	146	2	19167353
Pubmed	Clinical Significance of Stem Cell Biomarkers EpCAM, LGR5 and LGR4 mRNA Levels in Lymph Nodes of Colon Cancer Patients.	LGR4 LGR5	5.24e-05	3	146	2	35008827
Pubmed	R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.	LGR4 LGR5	5.24e-05	3	146	2	21693646
Pubmed	ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL.	ABCA1 ABCG4	5.24e-05	3	146	2	16902247
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ADCY9 SLC38A1 SLC30A5 NUP155 CELSR2 TENM3 KIAA1217 PHACTR4 MICAL3	7.69e-05	421	146	9	36976175
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	STK36 MYO7A TMC4 IGSF10 UBA1 BBX	8.06e-05	168	146	6	30631154
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLG5 PIEZO1 AMBRA1 LRRK1 ADCY9 NUP155 CELSR3 ABCA5 WDR90 DOCK6	8.51e-05	529	146	10	14621295
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	MUC5B DNAH7 ANAPC1 MAD1L1 KEL DOCK6	8.60e-05	170	146	6	23314748
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	CYP1A2 LGR4 LGR5	9.12e-05	21	146	3	27088858
Pubmed	Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle.	ABCA1 ABCA5	1.04e-04	4	146	2	33404706
Pubmed	ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.	ABCA1 ABCG4	1.04e-04	4	146	2	15210959
Pubmed	Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.	TAS2R42 TAS2R40	1.04e-04	4	146	2	23632330
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R42 TAS2R14 TAS2R40	1.05e-04	22	146	3	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R42 TAS2R14 TAS2R40	1.21e-04	23	146	3	20022913
Pubmed	Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.	LGR4 LGR5 FZD10	1.37e-04	24	146	3	31772170
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	CYP1A2 ABCA1 SLC22A11 SLCO4A1 ABCG4 ABCA5	1.72e-04	193	146	6	19343046
Pubmed	R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.	LGR4 LGR5	1.74e-04	5	146	2	22815884
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA1 ABCA5	1.74e-04	5	146	2	12532264
Pubmed	Duplications on human chromosome 22 reveal a novel Ret Finger Protein-like gene family with sense and endogenous antisense transcripts.	RFPL1 RFPL2	1.74e-04	5	146	2	10508838
Pubmed	Dispersed DNA variants underlie hearing loss in South Florida's minority population.	MYO7A STRC	1.74e-04	5	146	2	37996878
Pubmed	Human salivary mucin MG1 selectively forms heterotypic complexes with amylase, proline-rich proteins, statherin, and histatins.	MUC5B OVGP1	1.74e-04	5	146	2	9109822
Pubmed	Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.	LGR4 LGR5	1.74e-04	5	146	2	23393138
Pubmed	LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.	LGR4 LGR5	1.74e-04	5	146	2	37402772
Pubmed	Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.	LGR5 CELSR1	1.74e-04	5	146	2	33398177
Pubmed	NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.	LGR4 LGR5	1.74e-04	5	146	2	31867777
Pubmed	Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.	ABCA1 ABCG4	1.74e-04	5	146	2	23584088
Pubmed	The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells.	RFPL1 RFPL2	1.74e-04	5	146	2	11850190
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	CELSR1 CELSR3 CELSR2	1.76e-04	26	146	3	37228654
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R42 TAS2R14 TAS2R40	2.20e-04	28	146	3	15744053
Pubmed	Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.	CELSR1 CELSR2	2.60e-04	6	146	2	36712970
Pubmed	LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.	LGR5 BPTF	2.60e-04	6	146	2	30224759
Pubmed	Genome-wide association study of multiplex schizophrenia pedigrees.	CNTNAP5 TENM3	2.60e-04	6	146	2	22885689
Pubmed	Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.	LGR4 LGR5	2.60e-04	6	146	2	24225776
Pubmed	Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.	LGR4 LGR5	2.60e-04	6	146	2	21727895
Pubmed	Dystroglycan is a scaffold for extracellular axon guidance decisions.	CELSR1 CELSR3	2.60e-04	6	146	2	30758284
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R42 TAS2R14 TAS2R40	2.71e-04	30	146	3	12679530
Pubmed	Discovery and refinement of loci associated with lipid levels.	ABCA1 ATG7 GPR146 CELSR2 A2ML1 DOCK6	2.78e-04	211	146	6	24097068
Pubmed	Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.	CELSR1 CELSR3 CELSR2	3.29e-04	32	146	3	23177622
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	CELSR1 CELSR3 CELSR2	3.61e-04	33	146	3	25713288
Pubmed	IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.	ATG7 LGR5	3.63e-04	7	146	2	38081361
Pubmed	Identification of a new tissue-kallikrein-binding protein.	ITIH4 SERPINC1	3.63e-04	7	146	2	3643793
Pubmed	Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.	LGR4 LGR5	3.63e-04	7	146	2	37651925
Pubmed	Varying mechanical forces drive sensory epithelium formation.	MYO7A LGR5	3.63e-04	7	146	2	37922362
Pubmed	Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.	LGR4 LGR5	3.63e-04	7	146	2	29752411
Pubmed	Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.	UBA1 ANAPC1	3.63e-04	7	146	2	33082289
Pubmed	Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea.	MYO7A LGR5	3.63e-04	7	146	2	21472479
Pubmed	Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.	LGR4 LGR5	3.63e-04	7	146	2	32457899
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R42 TAS2R14 TAS2R40	3.94e-04	34	146	3	15496549
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	USP24 SLCO4A1 BPTF UBA1 WDHD1 ANAPC1 SVIL PHACTR4 MAD1L1 MICAL3 VDAC1	4.47e-04	774	146	11	15302935
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	LGR4 SLC38A1 BPTF BBX TENM3 KIAA1217 SVIL TTI1 IPO11	4.59e-04	536	146	9	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	LGR4 SLC38A1 BPTF BBX TENM3 KIAA1217 SVIL TTI1 IPO11	4.72e-04	538	146	9	10512203
Pubmed	R-spondins/Lgrs expression in tooth development.	LGR4 LGR5	4.82e-04	8	146	2	24616052
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	MYO7A STRC	4.82e-04	8	146	2	21165971
Pubmed	RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.	RFPL1 RFPL2	4.82e-04	8	146	2	12525704
Pubmed	Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium.	LGR4 LGR5	4.82e-04	8	146	2	24139799
Pubmed	Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells.	ATG7 AMBRA1	4.82e-04	8	146	2	22240590
Pubmed	A complex oscillating network of signaling genes underlies the mouse segmentation clock.	DACT2 MBOAT2 GFRA2	5.07e-04	37	146	3	17095659
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	RETREG2 TM9SF1 RHBDD2 LGR4 ADCY9 SLC35F5 SLC30A5 SLC16A6 CELSR2 TMEM168 TTI1 DOCK6 IPO11	5.57e-04	1061	146	13	33845483
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2AG2 OR2M3 OR2L13 OR2L2 OR4K15 OR10A5 OR2AG1	6.10e-04	340	146	7	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2AG2 OR2M3 OR2L13 OR2L2 OR4K15 OR10A5 OR2AG1	6.10e-04	340	146	7	11802173
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	CELSR3 CELSR2	6.18e-04	9	146	2	9693030
Pubmed	Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.	LGR4 LGR5	6.18e-04	9	146	2	21508962
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2AG2 OR2M3 OR2L13 OR2L2 OR4K15 OR10A5 OR2AG1	6.42e-04	343	146	7	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2AG2 OR2M3 OR2L13 OR2L2 OR4K15 OR10A5 OR2AG1	6.76e-04	346	146	7	14611657
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCG4 ABCA5	7.70e-04	10	146	2	11435397
Interaction	TSPAN15 interactions	GPR17 RETREG2 TM9SF1 PIEZO1 LGR4 TMC4 CNNM4 CELSR2 TM7SF2 PIGW FZD10 S1PR4	3.85e-07	276	136	12	int:TSPAN15
Interaction	YIPF3 interactions	SLC43A2 RETREG2 PIEZO1 SLC35F5 PIGW FZD10 NIPA2 CMKLR1 S1PR4	4.90e-06	186	136	9	int:YIPF3
Interaction	TOP3B interactions	STK36 ERCC2 MYO7A LONRF1 PIEZO1 ARPC1A ZBTB4 CYB561D2 SLCO4A1 AMBRA1 LRRK1 EDC4 ADCY9 TYK2 PCNX2 MST1R CELSR1 CELSR3 CELSR2 SVIL MAD1L1 PIGW MICAL3 WDR90 DOCK6 VDAC1	5.01e-06	1470	136	26	int:TOP3B
Interaction	ZW10 interactions	GPR17 FPR1 MFSD4A NUP155 MAD1L1 FZD10 CMKLR1 S1PR4	1.05e-05	155	136	8	int:ZW10
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3 CELSR2	2.25e-07	3	111	3	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3 CELSR2	2.25e-07	3	111	3	1189
GeneFamily	Solute carriers	SLC43A2 SLC22A11 SLC17A4 SLCO4A1 SLC4A3 SLC35F5 SLC38A1 SLC30A5 SLC16A6 SLC25A29 SLC39A7	3.15e-05	395	111	11	752
GeneFamily	Olfactory receptors, family 2	OR2AG2 OR2M3 OR2L13 OR2L2 OR2AG1	6.61e-04	113	111	5	149
GeneFamily	G protein-coupled receptors, Class A orphans	GPR17 LGR4 LGR5 GPR146	1.35e-03	78	111	4	262
GeneFamily	Ubiquitin like modifier activating enzymes	ATG7 UBA1	1.63e-03	10	111	2	100
GeneFamily	Taste 2 receptors	TAS2R42 TAS2R14 TAS2R40	1.75e-03	39	111	3	1162
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA5	3.24e-03	14	111	2	805
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR17 CELSR2 HMCN1 TENM3 QKI TMEM200C LGI1	2.20e-06	181	145	7	a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASGRF2 SLC4A3 PHKA1 TENM3 KIAA1217 QKI HRH3	3.03e-06	190	145	7	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	DLG5 PRSS16 ZBTB4 EDC4 SLC38A1 OVGP1 DCAF4L1	3.97e-06	198	145	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	distal-2-Hematologic-Interstitial_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC43A2 FPR1 GFRA2 SLC16A6 MS4A14 CMKLR1 MS4A6A	4.11e-06	199	145	7	d4caf296b6ce22a10b78d0efd4e018d867ccb78a
ToppCell	distal-Hematologic-Interstitial_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC43A2 FPR1 GFRA2 SLC16A6 MS4A14 CMKLR1 MS4A6A	4.11e-06	199	145	7	e25a67a196f226b60b4aa0ff0cf4471d66333445
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A FPR1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.11e-06	199	145	7	9545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A FPR1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.25e-06	200	145	7	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	RETREG2 CSMD3 SLC38A1 CELSR3 ZDHHC22 HRH3	1.47e-05	161	145	6	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GFRA2 SLC35F5 PHKA1 OVGP1 ZSCAN20 CELSR2	1.69e-05	165	145	6	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GFRA2 SLC35F5 PHKA1 OVGP1 ZSCAN20 CELSR2	1.69e-05	165	145	6	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	ABCA1 MYO7A GFRA2 CELSR1 ABCA5 CMKLR1	2.29e-05	174	145	6	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO4A1 TMC4 LGR5 STPG2 LRRC26 CA5A	2.29e-05	174	145	6	b4483d7d9f22f09ed7fa0b72305434a47ccaade0
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	ABCA1 MYO7A GFRA2 CELSR1 ABCA5 CMKLR1	2.52e-05	177	145	6	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAD51B MUC5B SAA1 CELSR1 KIAA1217 LRRC26	2.52e-05	177	145	6	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RAD51B MUC5B SAA1 CELSR1 KIAA1217 LRRC26	2.52e-05	177	145	6	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	SLCO4A1 ESAM MFSD4A STPG2 GPR146 KIAA1217	2.77e-05	180	145	6	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SLCO4A1 ESAM MFSD4A STPG2 GPR146 KIAA1217	2.77e-05	180	145	6	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 LGR4 ADTRP CSMD3 CNTNAP5 ABCA5	2.85e-05	181	145	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERCC2 GFRA2 CNNM4 QKI MS4A6A DCAF4L1	2.94e-05	182	145	6	4a85429d365c4b2d73fc921f261b4b7635ac40bd
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERCC2 GFRA2 CNNM4 QKI MS4A6A DCAF4L1	2.94e-05	182	145	6	53213af34af3337f5edc734d3b7b79e4349eac0d
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERCC2 GFRA2 CNNM4 QKI MS4A6A DCAF4L1	2.94e-05	182	145	6	7909089ed6325c44edd6f9b7e8b1d542398222ea
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A SLC4A3 ZNF568 MST1R MYOCD WDR90	3.23e-05	185	145	6	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	SLCO4A1 ESAM MBOAT2 GPR146 KIAA1217 DOCK6	3.23e-05	185	145	6	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A SLC4A3 ZNF568 MST1R MYOCD WDR90	3.23e-05	185	145	6	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 LGR4 MFSD4A XKR6 HMCN1 ABCA5	3.53e-05	188	145	6	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 LGR4 MFSD4A XKR6 HMCN1 ABCA5	3.53e-05	188	145	6	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 LGR4 MFSD4A XKR6 HMCN1 ABCA5	3.64e-05	189	145	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MUC5B TMC4 CELSR1 MGAT3 CELSR2 LRRC26	3.64e-05	189	145	6	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MUC5B TMC4 CELSR1 MGAT3 CELSR2 LRRC26	3.64e-05	189	145	6	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	SLC38A1 KIAA1217 SVIL MYOCD MICAL3 QKI	3.64e-05	189	145	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 CELSR1 TENM3 DOCK6 TMEM200C IPO11	3.75e-05	190	145	6	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	GPR17 RASGRF2 SLCO4A1 ESAM KIAA1217 DOCK6	3.75e-05	190	145	6	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 CELSR1 TENM3 DOCK6 TMEM200C IPO11	3.75e-05	190	145	6	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA1 ATG7 MYO7A GFRA2 CMKLR1 MS4A6A	3.75e-05	190	145	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 CELSR1 TENM3 DOCK6 TMEM200C IPO11	3.75e-05	190	145	6	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 SLCO4A1 ESAM LGR5 MBOAT2 KIAA1217	3.75e-05	190	145	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STK36 MUC5B TMC4 CELSR1 MGAT3 LRRC26	3.75e-05	190	145	6	576c45a30a4808b47433bc6c2c41396135556c40
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 LGR4 MFSD4A XKR6 HMCN1 ABCA5	3.75e-05	190	145	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC43A2 ATG7 MYO7A GFRA2 CMKLR1 MS4A6A	4.21e-05	194	145	6	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 LRRK1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.21e-05	194	145	6	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 PRSS16 DACT2 ITIH4 ZSCAN20 STRC	4.33e-05	195	145	6	fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	ABCA1 PIEZO1 ESAM HMCN1 SVIL IPO11	4.33e-05	195	145	6	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 LRRK1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.33e-05	195	145	6	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RASGRF2 ESAM GPR146 HMCN1 SVIL CA5A	4.45e-05	196	145	6	ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell	medial-Hematologic-Interstitial_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC43A2 FPR1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.58e-05	197	145	6	b90c8a41e99c87b46be699d03cd49c97a2ad51af
ToppCell	medial-Hematologic-Interstitial_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC43A2 FPR1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.58e-05	197	145	6	13aec816e21754eac590a12c3a9c795c41108277
ToppCell	medial-2-Hematologic-Interstitial_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC43A2 FPR1 GFRA2 MS4A14 CMKLR1 MS4A6A	4.58e-05	197	145	6	38a74eeb2a4c8d6a86b133f02f4e6c641f16a3ac
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 MYO7A FPR1 GFRA2 CMKLR1 MS4A6A	4.71e-05	198	145	6	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 FPR1 ADTRP MS4A14 CMKLR1 MS4A6A	4.71e-05	198	145	6	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ABCA1 MYO7A GFRA2 MS4A14 CMKLR1 MS4A6A	4.85e-05	199	145	6	2649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO4A1 ESAM LGR5 MBOAT2 GPR146 DOCK6	4.85e-05	199	145	6	7ed541309808f15d65a9c4b26be2050e077539e6
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC17A4 MUC5B TMC4 DNAH7 CELSR1 A2ML1	4.85e-05	199	145	6	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC43A2 MYO7A FPR1 MS4A14 CMKLR1 MS4A6A	4.85e-05	199	145	6	1413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC17A4 MUC5B TMC4 DNAH7 CELSR1 A2ML1	4.85e-05	199	145	6	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RASGRF2 ESAM EDC4 GPR146 HMCN1 DOCK6	4.85e-05	199	145	6	63c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO4A1 ESAM LGR5 MBOAT2 GPR146 DOCK6	4.85e-05	199	145	6	14a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ESAM MFSD4A BPTF HMCN1 KIAA1217 DOCK6	4.98e-05	200	145	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	DLG5 LGR4 MUC5B SAA1 ABCA5 KIAA1217	4.98e-05	200	145	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	mLN-Macrophage\|mLN / Region, Cell class and subclass	MYO7A FPR1 GFRA2 KEL CMKLR1 MS4A6A	4.98e-05	200	145	6	68d709afd226241e002dae6d6820bccd1cfd87a1
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B TMC4 XKR6 CELSR1 KIAA1217 SLC25A29	4.98e-05	200	145	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	mLN-(6)_Macrophage\|mLN / shred on region, Cell_type, and subtype	MYO7A FPR1 GFRA2 KEL CMKLR1 MS4A6A	4.98e-05	200	145	6	6dcba82a7d322102bae205543086e84c7655b3e0
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	STK36 ANO9 DLG5 ADCY9 MICAL3 IPO11	4.98e-05	200	145	6	c2df917900872453ea17a39928e39d071a6d3339
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYO7A FPR1 GFRA2 CMKLR1 MS4A6A CA5A	4.98e-05	200	145	6	a1ae299cf77580a6d1a728ee591888b6d70a19d6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 DLG5 XKR6 CSMD3 UGT3A2	8.32e-05	136	145	5	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADTRP SLC38A1 CNTNAP5 ABCA5 DCAF4L1	8.61e-05	137	145	5	81cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PIEZO1 ADTRP HMCN1 S1PR4 CA5A	1.13e-04	145	145	5	37580218f6a6f65a1d827cbcf59465f8827f9a55
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MST1R CNTNAP5 CLCN4 WDHD1 MYOCD	1.13e-04	145	145	5	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STK36 PIEZO1 SLC38A1 SPATA9 SLC25A29	1.13e-04	145	145	5	bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESAM CNTNAP5 MS4A14 SLC25A29 SLC39A7	1.49e-04	154	145	5	ce4b1e878cd88065fbfd2df18caf19703fec37d8
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 ARPC1A ADTRP DNAH7 SVIL	1.49e-04	154	145	5	6c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 FPR1 ZBTB4 LRRK1 GFRA2	1.63e-04	157	145	5	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DACT2 MUC5B LGR5 OVGP1 LRRC26	1.78e-04	160	145	5	6005948e400e781cdb876ba350b3ec8991e3945f
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A3 ITIH4 ABCG4 KEL MICAL3	1.78e-04	160	145	5	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A3 ITIH4 ABCG4 KEL MICAL3	1.78e-04	160	145	5	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	Club_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	MFSD4A MUC5B SAA1 ADRA1D LRRC26	1.83e-04	161	145	5	bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A3 ITIH4 ABCG4 KEL MICAL3	1.83e-04	161	145	5	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	Bronchial-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR17 COL15A1 LGR5 MBOAT2 CELSR2	1.89e-04	162	145	5	afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PRSS16 A2ML1 PIGW WDR90 DCAF4L1	2.11e-04	166	145	5	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CSMD3 IGSF10 PHKA1 CLCN4	2.11e-04	166	145	5	13027ae342994db4540e64eb910df1f42b160931
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	PRSS16 A2ML1 PIGW WDR90 DCAF4L1	2.11e-04	166	145	5	eb8d972326a734549675307e411fc795af66da70
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CSMD3 IGSF10 PHKA1 CLCN4	2.11e-04	166	145	5	b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright\|ICU-NoSEP / Disease, Lineage and Cell Type	STK36 ANO9 DLG5 ADCY9 MICAL3	2.17e-04	167	145	5	f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 CMKLR1 MS4A6A DCAF4L1 CA5A	2.17e-04	167	145	5	2dc3de562a26077cb76855b725cf278a272d3276
ToppCell	Tuft-tuft-1\|World / Class top	RASGRF2 MYO7A NBAS FZD10 SLC25A29	2.24e-04	168	145	5	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7\|TCGA-Lung / Sample_Type by Project: Shred V9	PRSS16 IL37 MFSD4A TMC4 OVGP1	2.30e-04	169	145	5	5f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	MYO7A PIEZO1 EDC4 GFRA2 MS4A14	2.43e-04	171	145	5	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCHS2 TMC4 HMCN1 FZD10 DOCK6	2.43e-04	171	145	5	a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANO9 ADTRP ITIH4 CELSR1 ARMC5	2.43e-04	171	145	5	5636ec11ed1f7aacf98cd9e85853ee1a05bd2cf2
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC43A2 ABCA1 MYO7A GFRA2 MS4A6A	2.43e-04	171	145	5	5e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TMC4 LGR5 MST1R HMCN1 TMEM168	2.49e-04	172	145	5	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TMC4 LGR5 MST1R HMCN1 TMEM168	2.49e-04	172	145	5	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 LGR4 MFSD4A HMCN1 ABCA5	2.56e-04	173	145	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	COL15A1 MYO7A CELSR2 CMKLR1 IPO11	2.70e-04	175	145	5	7de1023161233b64f11e130881c742f4cf2bff65
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	LRRK1 IGSF10 LRRC26 CMKLR1 MS4A6A	2.70e-04	175	145	5	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCA1 LGR4 LGR5 ABCA5 CA5A	2.77e-04	176	145	5	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LGR4 ADTRP STPG2 CNTNAP5 ABCA5	2.77e-04	176	145	5	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 DLG5 CSMD3 MBOAT2 ABCA5	2.92e-04	178	145	5	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DCHS2 SLC17A4 DNAH7 TENM3 MICAL3	2.92e-04	178	145	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GFRA2 OVGP1 MGAT3 TMEM200C LGI1	2.92e-04	178	145	5	3e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 MFSD4A MUC5B CELSR1 KIAA1217	3.00e-04	179	145	5	1fc1f252ca943a2f649d1e627f56acbf15f8e058
Disease	triglycerides in LDL measurement	ABCA1 SLC38A1 BPTF CELSR2	1.35e-04	56	137	4	EFO_0022320
Disease	triglyceride measurement, intermediate density lipoprotein measurement	ABCA1 SLC38A1 GPR146 BPTF CELSR2	1.73e-04	111	137	5	EFO_0004530, EFO_0008595
Disease	HDL cholesterol change measurement	ABCA1 MBOAT2 DOCK6	1.85e-04	24	137	3	EFO_0007805
Disease	triglycerides in medium LDL measurement	ABCA1 SLC38A1 BPTF CELSR2	2.01e-04	62	137	4	EFO_0022322
Disease	Periodontal Pocket	RHBDD2 XKR6 TENM3	2.09e-04	25	137	3	EFO_1001393
Disease	response to TNF antagonist, joint damage measurement	RAD51B CSMD3 GFRA2	2.09e-04	25	137	3	EFO_0004653, EFO_0005413
Disease	intermediate coronary syndrome (is_implicated_in)	ITIH4 SERPINC1	2.12e-04	5	137	2	DOID:8805 (is_implicated_in)
Disease	alcohol consumption measurement	CYP1A2 DLG5 RASGRF2 ARPC1A CSMD3 MBOAT2 GFRA2 STPG2 SLC38A1 MST1R NBAS CNTNAP5 MAD1L1 MICAL3 WDR90 CA5A	2.18e-04	1242	137	16	EFO_0007878
Disease	triglycerides in small LDL measurement	ABCA1 SLC38A1 BPTF CELSR2	2.42e-04	65	137	4	EFO_0022323
Disease	aggressive behaviour measurement, ADHD symptom measurement	XKR6 MST1R BBX MAD1L1	2.88e-04	68	137	4	EFO_0007826, EFO_0007860
Disease	primary ciliary dyskinesia (is_implicated_in)	STK36 DNAH7	3.17e-04	6	137	2	DOID:9562 (is_implicated_in)
Disease	right ventricular ejection fraction measurement	ABCA1 XKR6 SVIL	3.63e-04	30	137	3	EFO_0021816
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	4.43e-04	7	137	2	DOID:0050580 (is_implicated_in)
Disease	osteopetrosis (implicated_via_orthology)	LRRK1 CLCN4	4.43e-04	7	137	2	DOID:13533 (implicated_via_orthology)
Disease	serum albumin measurement	SLC43A2 CYP1A2 ADCY9 GFRA2 SLC38A1 ABCG4 BBX ABCA5 MAD1L1 MICAL3	4.61e-04	592	137	10	EFO_0004535
Disease	response to paliperidone, schizophrenia symptom severity measurement	RASGRF2 USP24 XKR6 CSMD3 HMCN1 SVIL	5.32e-04	216	137	6	EFO_0007925, EFO_0007927
Disease	eosinophil count	RAD51B FPR1 SLC17A4 RHBDD2 XKR6 ADTRP DNAH7 ZNF568 ITIH4 SLC38A1 BPTF CELSR1 ANAPC1 UGT3A2 VDAC1 S1PR4 CA5A	5.50e-04	1488	137	17	EFO_0004842
Disease	advanced glycation end-product measurement	CYP1A2 SLC38A1	7.54e-04	9	137	2	EFO_0007819
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ABCA1 XKR6 SLC38A1 CELSR2 DOCK6	7.57e-04	153	137	5	EFO_0004611, EFO_0020944
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	ABCA1 XKR6 SLC38A1 BPTF CELSR2 DOCK6	9.82e-04	243	137	6	EFO_0004612, EFO_0020944
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	ABCA1 SLC38A1 GPR146 BPTF CELSR2	1.09e-03	166	137	5	EFO_0004530, EFO_0004611
Disease	1-methylxanthine measurement	CYP1A2 SLC38A1	1.15e-03	11	137	2	EFO_0021174
Disease	5-acetylamino-6-amino-3-methyluracil measurement	CYP1A2 SLC38A1	1.15e-03	11	137	2	EFO_0800951
Disease	neurotic disorder	XKR6 BBX TENM3 MAD1L1	1.28e-03	101	137	4	EFO_0004257
Disease	neuropathic pain	SLC17A4 GFRA2 ZSCAN20	1.37e-03	47	137	3	EFO_0005762
Disease	total lipids in lipoprotein particles measurement	ABCA1 CELSR2 DOCK6	1.45e-03	48	137	3	EFO_0022309
Disease	Colorectal Carcinoma	CYP1A2 ABCA1 ERCC2 RASGRF2 LGR5 CSMD3 OVGP1 ABCA5 UGT3A2 QKI	1.67e-03	702	137	10	C0009402
Disease	waist-hip ratio	RAD51B CYP1A2 ABCA1 COL15A1 ATG7 SLC22A11 SLC17A4 LGR4 ZNF568 SLC35F5 BPTF MGAT3 BBX DOCK6	1.73e-03	1226	137	14	EFO_0004343
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	ABCA1 SLC38A1 GPR146 BPTF CELSR2 DOCK6	1.81e-03	274	137	6	EFO_0004530, EFO_0004612
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	ABCA1 XKR6 SLC38A1 BPTF CELSR2 DOCK6	1.88e-03	276	137	6	EFO_0004612, EFO_0020943
Disease	HMG CoA reductase inhibitor use measurement	ABCA1 SLC38A1 GPR146 CELSR2 DOCK6	1.93e-03	189	137	5	EFO_0009932
Disease	phospholipids in medium HDL measurement	ABCA1 CELSR2 DOCK6	2.15e-03	55	137	3	EFO_0022295
Disease	chenodeoxycholate measurement	FPR1 HMCN1	2.16e-03	15	137	2	EFO_0010471
Disease	Tinnitus, response to cisplatin	ADRA1D TENM3	2.16e-03	15	137	2	GO_0072718, HP_0000360
Disease	omega-3 polyunsaturated fatty acid measurement	ABCA1 TMC4 CELSR2 DOCK6	2.27e-03	118	137	4	EFO_0010119
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ABCA1 USP24 SLC38A1 BPTF CELSR2 DOCK6	2.44e-03	291	137	6	EFO_0008317, EFO_0020946
Disease	maximal oxygen uptake measurement, response to exercise	SLC43A2 QKI	2.46e-03	16	137	2	EFO_0004887, EFO_0007768
Disease	metabolic syndrome	ABCA1 EDC4 SLC38A1 BPTF CELSR2	2.47e-03	200	137	5	EFO_0000195
Disease	total lipids in medium HDL measurement	ABCA1 CELSR2 DOCK6	2.51e-03	58	137	3	EFO_0022310
Disease	colorectal health	PKD1L1 STPG2 PCNX2 ADRA1D MAD1L1	2.52e-03	201	137	5	EFO_0008460
Disease	cholesterol in medium HDL measurement	ABCA1 CELSR2 DOCK6	2.63e-03	59	137	3	EFO_0021903
Disease	cognitive function measurement	RAD51B PIEZO1 ADTRP CSMD3 GFRA2 SLC38A1 MST1R ADRA1D CNTNAP5 MGAT3 BBX KIAA1217 MAD1L1 UGT3A2 TMEM200C	2.77e-03	1434	137	15	EFO_0008354
Disease	triacylglycerol 56:9 measurement	CNTNAP5 MAGEC1	2.78e-03	17	137	2	EFO_0010436
Disease	phospholipids in HDL measurement	ABCA1 CELSR2 DOCK6	2.89e-03	61	137	3	EFO_0022293
Disease	docosahexaenoic acid measurement	ABCA1 TMC4 CELSR2 DOCK6	2.96e-03	127	137	4	EFO_0007761
Disease	HETE measurement	RAD51B PIEZO1 NBAS	3.03e-03	62	137	3	EFO_0801166
Disease	level of Phosphatidylinositol (18:0_18:1) in blood serum	TMC4 DOCK6	3.12e-03	18	137	2	OBA_2045155
Disease	polyunsaturated fatty acid measurement	ABCA1 SLC38A1 CELSR2 DOCK6	3.31e-03	131	137	4	EFO_0010733
Disease	familial hyperlipidemia (biomarker_via_orthology)	ABCA1 SERPINC1	3.47e-03	19	137	2	DOID:1168 (biomarker_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	STK36 CELSR2	3.47e-03	19	137	2	DOID:10908 (implicated_via_orthology)
Disease	phospholipid measurement	ABCA1 SLC38A1 GPR146 DOCK6	4.19e-03	140	137	4	EFO_0004639
Disease	phospholipids:total lipids ratio	ABCA1 USP24 BPTF CELSR2 DOCK6	4.24e-03	227	137	5	EFO_0020946
Disease	skin hydration measurement	PKD1L1 FZD10	4.24e-03	21	137	2	EFO_0009586
Disease	bipolar I disorder	ITIH4 CNNM4 MAD1L1 PIGW	4.30e-03	141	137	4	EFO_0009963
Disease	fatty acid measurement	ABCA1 TMC4 XKR6 SLC38A1 BPTF CELSR2 DOCK6	4.36e-03	436	137	7	EFO_0005110

Protein segments in the cluster

Peptide	Gene	Start	Entry
LARGLKLTFDSSFSP	VDAC1	91	P21796
TASLLFPQSSSIVIF	ABCA5	286	Q8WWZ7
QPAETSRFLLFSALA	ABCG4	496	Q9H172
SRFLLFSALATATAL	ABCG4	501	Q9H172
VVKSTAASLAFPFLL	SLC4A3	1171	P48751
PAVSAFFSLAALAEV	BBX	891	Q8WY36
TNSSSVAIAILVPFF	CSMD3	3626	Q7Z407
LSLPTTITSAAFTLR	ARID3C	176	A6NKF2
SRSDSFLTFAPSVLS	EVX1	376	P49640
FLTFAPSVLSKASSV	EVX1	381	P49640
ALVSLAVAFTFPFIT	GPR17	221	Q13304
PSSLSSLARIFSILS	ABCA1	2181	O95477
ASFSLSLTFTSRLAP	A2ML1	516	A8K2U0
AFRDLLFTTLAFPVS	ADTRP	81	Q96IZ2
ASATASPFFRALLSG	ARMC5	766	Q96C12
FAALVAAFTLRSINP	CLCN4	296	P51793
VLRFDSSAPFLSSTT	CELSR1	1321	Q9NYQ6
VLRFDSSAPFIASSS	CELSR2	1246	Q9HCU4
TFLLAFSPDRTLLAS	AMBRA1	56	Q9C0C7
VLASALFSSSAVPFL	ANO9	356	A1A5B4
DNIFLSPLSISTAFA	SERPINC1	106	P01008
TVQRFLFTPLATTAT	BPTF	2331	Q12830
FLPLLSVSFVSENSV	ARPC1A	246	Q92747
LNLSLAYSFVTPLTS	ITIH4	576	Q14624
STVFLSSTIFLVLPF	OR2L2	196	Q8NH16
LSAANITLFTPSSFF	MUC5B	511	Q9HC84
ADFSPAFLSTTLSAL	RAD51B	76	O15315
FSLAATAQAAPRIIT	QKI	216	Q96PU8
SVPFSATELLLASAI	CYP1A2	6	P05177
LQTIRFSPDIFSSVS	EDC4	391	Q6P2E9
ETISAFTSDPALLSF	ANAPC1	1736	Q9H1A4
LLFTSVVTPKALADF	OR2AG2	71	A6NM03
AVLIASTRSPISFLS	MICAL3	641	Q7RTP6
PAFLSSLTLELFSRQ	MAD1L1	701	Q9Y6D9
PVSRSFSSTLLSIFQ	MAGEC1	201	O60732
FSSTLLSIFQSSPER	MAGEC1	206	O60732
FSSTLLSLFQSSPER	MAGEC1	381	O60732
LEFLSKLSSIIPSAF	MAGEC3	586	Q8TD91
RTSFSPTIQTFILSA	MBOAT2	356	Q6ZWT7
RELASLSPNLVSSFF	MGAT3	36	Q09327
FTSSLAISLVFAVIP	MFSD4A	86	Q8N468
AASVLEFPAFLSESL	LRRK1	536	Q38SD2
AFTVGSFLLSAITLP	SLC43A2	91	Q8N370
DASLLSVVSFPAFAV	PHKA1	256	P46020
PLAAAIAASDFRTSV	LONRF1	181	Q17RB8
FSFTPLIQRSLEFSV	IPO11	286	Q9UI26
PSSLASDRFNFILAS	DCAF4L1	66	Q3SXM0
FTVALTASEALSPLA	EID2B	146	Q96D98
AVSASTVFLSLRPFL	PCNX2	1111	A6NKB5
FPSLLILSCSDTSIF	OR2M3	181	Q8NG83
ADSGFLSLSSFLLLV	OR4K15	201	Q8NH41
LLALDAFSSDSIPLF	DLG5	1706	Q8TDM6
DVSFSLASLPVSFRK	NIPA2	301	Q8N8Q9
LADFSPLTLLANFAT	ERCC2	391	P18074
SIPDFAFTNLSSLVV	LGR4	191	Q9BXB1
LLFTSVVTPKALADF	OR2AG1	71	Q9H205
SLSSLPTVLSIFLFN	OR51A2	76	Q8NGJ7
SLSSLPTVLSIFLFN	OR51A4	76	Q8NGJ6
LFVISPASSFIGDLS	NBAS	166	A2RRP1
ARFIISTSITTAPAA	PHACTR4	196	Q8IZ21
ALTTSSPSIFNIDFL	MYOCD	906	Q8IZQ8
LSFLVPSLLQFTFSE	NUP155	261	O75694
TSSSLVSAFLAPILA	OXER1	86	Q8TDS5
CSVDSLLPFTLSFVR	HMCN1	451	Q96RW7
PLAVFASSFSISLVV	DCHS2	2986	Q6V1P9
LPLAFVATLTAFIFS	TM7SF2	131	O76062
PSQLSAFRTLLFSAL	CA5A	256	P35218
SSAFTVLTFLIDPAR	FZD10	241	Q9ULW2
RLTTATAALSFPSAA	IGSF10	1071	Q6WRI0
IRPEIFFALASSLSS	IL37	86	Q9NZH6
SAGLPARLTLEFSAF	ATG7	56	O95352
SAQALFPFEASLLTS	DACT2	586	Q5SW24
PAISTLARSAIFSVT	DOCK6	316	Q96HP0
FFLDETLRSLASPSS	GFRA2	11	O00451
LAVSFRAFASSVTPD	DNAH7	1671	Q8WXX0
ASPTFSSLLDVFLST	ADCY9	781	O60503
TFFAPALDVIRGSLS	ESAM	196	Q96AP7
LRAFPVNAATFATVT	SLC25A29	256	Q8N8R3
SRTLFIVLFFLPSDV	MS4A14	151	Q96JA4
SLGIILASASFSPNF	MS4A6A	61	Q9H2W1
TASTLEFFTPFLSVT	HRH3	201	Q9Y5N1
SKLLAFSSSFVTPLL	GPR146	281	Q96CH1
VSVLRFDSSAPFLAS	CELSR3	1391	Q9NYQ7
TLIPSTFFRDFAISV	COL15A1	81	P39059
RTLQLAASVPFFAIS	SLC22A11	256	Q9NSA0
SIASSLVVLFFLPET	SLC22A11	501	Q9NSA0
FISSFLTLFIPLAAN	SLC17A4	146	Q9Y2C5
REGLLFTALAASTFS	S1PR4	121	O95977
LVPSSLVESFSIFRS	PKD1L1	2501	Q8TDX9
TIFVAVLARPGSSLF	CYB561D2	31	O14569
ALSFVTTQAPSLLLF	CNTNAP5	1041	Q8WYK1
PVAFLSFSSLINLTF	LGR5	781	O75473
SFSSLINLTFISPEV	LGR5	786	O75473
SFSSLPTEIQSLLFL	OR10A5	16	Q9H207
ILVRAEFSSTSLPQF	OVGP1	381	Q12889
VFVLTFSAPLATVLS	SLC16A6	71	O15403
STSLFLLFPFIGITS	OR2L13	201	Q8N349
LTSTVFIFIPFTLSL	TAS2R14	181	Q9NYV8
LVSLSFSFPLSRDVF	TAS2R40	151	P59535
SLTSFIPFSLFLTSL	TAS2R42	186	Q7RTR8
LSASTVPLTFLFVDR	RFPL1	226	O75677
TSGLFTLILAAVFPS	SLC35F5	276	Q8WV83
AVLLAFLSPASQISS	TRGV1	6	A0A0A0MS02
SFNFAPRLFILSSSS	SVIL	1996	O95425
PRLFILSSSSGDFAA	SVIL	2001	O95425
FVDSSLSAFALLPLQ	TMEM200C	371	A6NKL6
ILSVFIPSLFLENFS	PIGF	21	Q07326
TSIPVRSLELFFATS	RASGRF2	691	O14827
SSRPLRVLSFVAAAF	FPR1	236	P21462
LSSSSLRPFFLLSVS	RETREG2	96	Q8NC44
SADTIRALFVSAFPQ	KIAA1217	206	Q5T5P2
ADSLPIALVSFAVSA	SLC26A10	281	Q8NG04
SLFEIISFPAKTALT	SPATA9	131	Q9BWV2
FAVVFSPIQLSSLTS	STRC	1696	Q7RTU9
SASPRTIVSFLSVAL	STK36	1056	Q9NRP7
TSAFTAIAILAVDFP	PIGW	136	Q7Z7B1
SLVLGVSSRSFFSFL	SAA1	11	P0DJI8
VVIFFTFLSSIPALT	SLCO4A1	586	Q96BD0
ADLLLSATVLPFSAT	ADRA1D	141	P25100
LAFFLSSPSLVFRDT	CMKLR1	166	Q99788
ASSASAFLTAPLLEF	CMTM3	61	Q96MX0
ASTFFPQVLRASSEL	LINC01561	11	Q8N1V8
RFLATEVSQFSPSLI	CNNM4	556	Q6P4Q7
FTISSRVISFALFAS	XKR6	366	Q5GH73
LIFPHSTTVLALAFS	WDR90	1201	Q96KV7
AFLTLLPTSISQFFS	ZDHHC22	161	Q8N966
TKAFLAILSESPFSE	ZSCAN20	491	P17040
IFPLSSDIVTSRQSF	ZNF568	161	Q3ZCX4
ATVLISAAPFFVLFL	SLC39A7	141	Q92504
EVPSATFFTALLSLL	RHBDD2	16	Q6NTF9
TFFTALLSLLVSGPR	RHBDD2	21	Q6NTF9
PFLSLTARESTFTIA	STPG2	41	Q8N412
SLSFDPKDIFLASAS	WDHD1	141	O75717
ISSLPETTQNFLFFL	TMC4	636	Q7Z404
SVLAASSPFFREALL	ZBTB4	46	Q9P1Z0
ASLTLVFERSPFLTQ	TENM3	911	Q9P273
RLSATTVPLTFLFVD	RFPL2	286	O75678
VIFAVLLFFSSLETP	TMEM168	206	Q9H0V1
ISFKSLVASLAEPDF	UBA1	301	P22314
QPSASSILESLFRSF	USP24	1151	Q9UPU5
SAIFFILSANILSSP	SLC30A5	351	Q8TAD4
SPVRFDTFDSLSLSI	USP30	241	Q70CQ3
SVSELFSSILVPGFF	PIEZO1	676	Q92508
PFVAILSTSFGSLEF	UGT3A2	161	Q3SY77
LIFASVASSAPVRAV	PRSS16	201	Q9NQE7
PLLVSSSFSRVDLFN	MST1R	426	Q04912
LTVPVLFFTVRSSLF	SLC38A1	366	Q9H2H9
IILTTSLFSVPFFLT	TM9SF1	376	O15321
FASFLPGISTALTRL	TTI1	206	O43156
SLPSRAAALSFVSLV	TYK2	406	P29597
TLAALFVREAFGPST	KEL	421	P23276
RLTLSPLTAFSDAAF	LRRC26	236	Q2I0M4
LTSIDPVLTTFFNLS	LRRC51	91	Q96E66
SFLFTPSLQLLLFTS	LGI1	86	O95970
VLFSPSLATAASLLE	MYO7A	346	Q13402