Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	2.85e-10	37	151	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	3.58e-10	38	151	8	GO:0070001
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ	4.38e-08	14	151	5	GO:0003964
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	9.95e-07	11	151	4	GO:0004523
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ	9.50e-06	38	151	5	GO:0034061
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.70e-05	21	151	4	GO:0035613
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 PAPOLB ERVK-7 ERVK-10 POLR3B ERVK-8 POLQ	1.59e-04	152	151	7	GO:0016779
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.71e-04	37	151	4	GO:0016891
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC4A8 TUSC3 RYR3 ITPR1 CACNG2 SLC9A2 KCNJ2 KCNJ14 SLC28A1 SCNN1G KCNAB1 CNGB1	2.23e-04	465	151	12	GO:0046873
GeneOntologyMolecularFunction	ATP-dependent activity	DDX19B DDX19A KIF27 IPO8 SPG7 HSPH1 SRCAP ABCA10 ABCA9 ABCA6 MYH14 DDX3Y POLQ DNAH9	2.40e-04	614	151	14	GO:0140657
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.01e-04	46	151	4	GO:0016893
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 LGMN SPG7 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ATG4B ERVK-8 ERVK-19 ERVK-24	4.39e-04	430	151	11	GO:0004175
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX19B DDX19A KIF27 SPG7 SRCAP ABCA10 ABCA9 ABCA6 DDX3Y POLQ DNAH9	5.42e-04	441	151	11	GO:0016887
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	RYR3 ITPR1 KCNJ2 KCNJ14 SCNN1G CNGB1	6.91e-04	140	151	6	GO:0099094
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC4A8 TUSC3 SLC25A14 RYR3 ITPR1 CACNG2 SLC9A2 KCNJ2 KCNJ14 SLC28A1 SCNN1G KCNAB1 CNGB1	9.72e-04	627	151	13	GO:0022890
GeneOntologyMolecularFunction	dynein light intermediate chain binding	HOOK1 HOOK2 DNAH9	1.21e-03	28	151	3	GO:0051959
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 LGMN SPG7 RBP3 ERVK-7 ERVK-21 ERVK-9 ERVK-10 MYSM1 ATG4B ERVK-8 ERVK-19 ERVK-24	1.42e-03	654	151	13	GO:0008233
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC4A8 IPO8 TUSC3 SLC25A14 ABCA10 ABCA9 RYR3 ITPR1 CACNG2 SLC9A2 ABCA6 KCNJ2 KCNJ14 SLC28A1 SCNN1G KCNAB1 SLC25A44 SLC2A12 CNGB1	1.49e-03	1180	151	19	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC4A8 TUSC3 SLC25A14 RYR3 ITPR1 CACNG2 SLC9A2 KCNJ2 KCNJ14 SLC28A1 SCNN1G KCNAB1 CNGB1	1.63e-03	664	151	13	GO:0008324
GeneOntologyMolecularFunction	transporter activity	PITPNM2 SLC4A8 IPO8 TUSC3 SLC25A14 ABCA10 ABCA9 RYR3 ITPR1 CACNG2 SLC9A2 ABCA6 KCNJ2 KCNJ14 SLC28A1 SCNN1G KCNAB1 SLC25A44 SLC2A12 CNGB1	1.73e-03	1289	151	20	GO:0005215
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR3 ITPR1 CNGB1	1.96e-03	33	151	3	GO:0005217
GeneOntologyMolecularFunction	O-acetyltransferase activity	CHAT CRAT	1.98e-03	9	151	2	GO:0016413
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 SAMD8 LRRK2 PAPOLB DGKB ERVK-7 ERVK-10 STK3 MST1R JAK3 STK11 POLR3B GUCY2D ERVK-8 POLQ ADPGK	2.00e-03	938	151	16	GO:0016772
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.87e-06	13	151	4	GO:0015074
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ	2.61e-05	48	151	5	GO:0000731
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 FLOT1	3.79e-05	85	151	6	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 FLOT1	3.79e-05	85	151	6	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 FLOT1	4.91e-05	89	151	6	GO:0006949
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission	LGMN SLC4A8 APP CACNG2 PTPN5 STX3 NF1 RIMS1 FLOT1	5.64e-05	233	151	9	GO:0050806
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	LGMN SLC4A8 LRRK2 DGKB CHAT DCC APP CACNG2 PTPN5 STX3 NF1 GUCY1B1 SORCS3 RIMS1 FLOT1	1.10e-04	663	151	15	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	LGMN SLC4A8 LRRK2 DGKB CHAT DCC APP CACNG2 PTPN5 STX3 NF1 GUCY1B1 SORCS3 RIMS1 FLOT1	1.11e-04	664	151	15	GO:0099177
GeneOntologyBiologicalProcess	lysosomal transport	LRRK2 ASB14 LYST CACNG2 HOOK1 HOOK2 STX7	1.25e-04	151	151	7	GO:0007041
Domain	ARM-type_fold	NCAPD3 RAP1GDS1 IPO8 DOCK8 DOCK9 LRRK2 INTS1 HSPBP1 LYST PPP4R4 RYR3 ITPR1 NF1 CTNNBL1	3.79e-07	339	144	14	IPR016024
Domain	KN_motif	KANK1 KANK3 KANK4	1.79e-06	4	144	3	IPR021939
Domain	KN_motif	KANK1 KANK3 KANK4	1.79e-06	4	144	3	PF12075
Domain	ABC_A	ABCA10 ABCA9 ABCA6	9.38e-05	12	144	3	IPR026082
Domain	ARM-like	NCAPD3 RAP1GDS1 IPO8 DOCK8 LRRK2 HSPBP1 PPP4R4 NF1 CTNNBL1	2.51e-04	270	144	9	IPR011989
Domain	-	NCAPD3 RAP1GDS1 IPO8 LRRK2 HSPBP1 PPP4R4 NF1 CTNNBL1	3.31e-04	222	144	8	1.25.10.10
Domain	-	LRRK2 ASB14 ANKRD44 KANK1 KANK3 KANK4 CAMTA1 FEM1A	6.89e-04	248	144	8	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	LRRK2 ASB14 ANKRD44 KANK1 KANK3 KANK4 CAMTA1 FEM1A	8.04e-04	254	144	8	IPR020683
Domain	RIH_assoc-dom	RYR3 ITPR1	8.68e-04	6	144	2	IPR013662
Domain	HNOB_dom_associated	GUCY1B1 GUCY2D	8.68e-04	6	144	2	IPR011645
Domain	HOOK	HOOK1 HOOK2	8.68e-04	6	144	2	PF05622
Domain	Myb-like_dom	GON4L SNAPC4	8.68e-04	6	144	2	IPR017877
Domain	Ins145_P3_rec	RYR3 ITPR1	8.68e-04	6	144	2	PF08709
Domain	DUF3398	DOCK8 DOCK9	8.68e-04	6	144	2	PF11878
Domain	RIH_assoc	RYR3 ITPR1	8.68e-04	6	144	2	PF08454
Domain	RIH_dom	RYR3 ITPR1	8.68e-04	6	144	2	IPR000699
Domain	Ins145_P3_rcpt	RYR3 ITPR1	8.68e-04	6	144	2	IPR014821
Domain	Ryanodine_recept-rel	RYR3 ITPR1	8.68e-04	6	144	2	IPR015925
Domain	-	RYR3 ITPR1	8.68e-04	6	144	2	1.25.10.30
Domain	HNOBA	GUCY1B1 GUCY2D	8.68e-04	6	144	2	PF07701
Domain	Hook-related_fam	HOOK1 HOOK2	8.68e-04	6	144	2	IPR008636
Domain	RYDR_ITPR	RYR3 ITPR1	8.68e-04	6	144	2	PF01365
Domain	DOCK_C/D_N	DOCK8 DOCK9	8.68e-04	6	144	2	IPR021816
Domain	Ankyrin_rpt	LRRK2 ASB14 ANKRD44 KANK1 KANK3 KANK4 CAMTA1 FEM1A	9.83e-04	262	144	8	IPR002110
Domain	Carn_acyl_trans	CHAT CRAT	1.21e-03	7	144	2	IPR000542
Domain	Carn_acyltransf	CHAT CRAT	1.21e-03	7	144	2	PF00755
Domain	ACYLTRANSF_C_1	CHAT CRAT	1.21e-03	7	144	2	PS00439
Domain	ACYLTRANSF_C_2	CHAT CRAT	1.21e-03	7	144	2	PS00440
Domain	Ig_E-set	PKHD1L1 MST1R KCNJ2 KCNJ14 CAMTA1	1.27e-03	104	144	5	IPR014756
Domain	Helicase_C	DDX19B DDX19A SRCAP DDX3Y POLQ	1.44e-03	107	144	5	PF00271
Domain	HELICc	DDX19B DDX19A SRCAP DDX3Y POLQ	1.44e-03	107	144	5	SM00490
Domain	Helicase_C	DDX19B DDX19A SRCAP DDX3Y POLQ	1.50e-03	108	144	5	IPR001650
Domain	HELICASE_CTER	DDX19B DDX19A SRCAP DDX3Y POLQ	1.56e-03	109	144	5	PS51194
Domain	HELICASE_ATP_BIND_1	DDX19B DDX19A SRCAP DDX3Y POLQ	1.56e-03	109	144	5	PS51192
Domain	DEXDc	DDX19B DDX19A SRCAP DDX3Y POLQ	1.56e-03	109	144	5	SM00487
Domain	Helicase_ATP-bd	DDX19B DDX19A SRCAP DDX3Y POLQ	1.63e-03	110	144	5	IPR014001
Domain	TIG	PKHD1L1 MST1R CAMTA1	1.72e-03	31	144	3	PF01833
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10 ERVK-24	3.51e-10	4	152	4	10469592
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	1.15e-09	12	152	5	14557543
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-21 ERVK-19	1.75e-09	5	152	4	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	8.96e-09	94	152	8	21542922
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PITPNM2 SPG7 DOCK9 INTS1 SRCAP LYST FANCA MST1R JAK3 DIP2A FAT1 KANK3 DUSP16 BANP CPSF1 BCAM SNAPC4 FEM1A TOP3A TJP3	8.45e-08	1105	152	20	35748872
Pubmed	Kank proteins: a new family of ankyrin-repeat domain-containing proteins.	KANK1 KANK3 KANK4	3.26e-07	4	152	3	17996375
Pubmed	Kank proteins: structure, functions and diseases.	KANK1 KANK3 KANK4	3.26e-07	4	152	3	19554261
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	3.26e-07	4	152	3	7983737
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	SLC4A8 SPG7 TUSC3 APP JMJD1C CREM TBC1D32 EGF KCNJ2 SCNN1G FEM1A	7.95e-07	371	152	11	15747579
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-10 ERVK-24	1.02e-06	18	152	4	18664271
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	IPO8 DOCK8 DOCK9 KANK1 ITSN2 CPSF1 UTRN	1.37e-06	125	152	7	29467281
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	1.62e-06	6	152	3	15063128
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FNDC3B NCAPD3 GON4L CC2D1B JMJD1C ITPR1 FANCA DIP2A WASHC5 OSBPL11 HOOK2 TOP3A MOCOS	6.15e-06	650	152	13	38777146
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA10 ABCA9 ABCA6	9.60e-06	10	152	3	11435397
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	9.60e-06	10	152	3	12970426
Pubmed	Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia.	JAK3 SETBP1	1.90e-05	2	152	2	23832011
Pubmed	FAT1 inhibits AML autophagy and proliferation via downregulating ATG4B expression.	FAT1 ATG4B	1.90e-05	2	152	2	37952564
Pubmed	Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.	LRRK2 APP	1.90e-05	2	152	2	28720718
Pubmed	NAPE-specific phospholipase D regulates LRRK2 association with neuronal membranes.	NAPEPLD LRRK2	1.90e-05	2	152	2	33706934
Pubmed	KANK family proteins in cancer.	KANK1 KANK3	1.90e-05	2	152	2	33309958
Pubmed	Transmissible spongiform encephalopathy in the gray tremor mutant mouse.	SOX10 KRT71	1.90e-05	2	152	2	3855546
Pubmed	Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group.	JAK3 SETBP1	1.90e-05	2	152	2	26980750
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.90e-05	2	152	2	9060628
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.90e-05	2	152	2	9460924
Pubmed	Feedback activation of neurofibromin terminates growth factor-induced Ras activation.	NF1 EGF	1.90e-05	2	152	2	26861207
Pubmed	Neurofibromatosis type 1 protein and amyloid precursor protein interact in normal human melanocytes and colocalize with melanosomes.	APP NF1	1.90e-05	2	152	2	16374483
Pubmed	DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.	DDX19B DDX19A	1.90e-05	2	152	2	30699353
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF7 RAP1GDS1 DOCK9 DCC PRAMEF8 SRCAP ITPR1 DUSP16 UTRN	3.37e-05	363	152	9	14691545
Pubmed	Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins.	KANK1 KANK3 KANK4	4.40e-05	16	152	3	33253712
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT1 FAT2	5.68e-05	3	152	2	15744052
Pubmed	Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice.	CHAT APP	5.68e-05	3	152	2	24844149
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	5.68e-05	3	152	2	9971820
Pubmed	The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein.	APP FLOT1	5.68e-05	3	152	2	16480949
Pubmed	Neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice brains.	APP NF1	5.68e-05	3	152	2	21170735
Pubmed	Hypoxia increases amyloid-β level in exosomes by enhancing the interaction between CD147 and Hook1.	APP HOOK1	5.68e-05	3	152	2	29423001
Pubmed	APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis.	APP EGF	5.68e-05	3	152	2	33009641
Pubmed	Loss of presenilin function is associated with a selective gain of APP function.	DCC APP	5.68e-05	3	152	2	27196744
Pubmed	An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.	STK11 DIXDC1	5.68e-05	3	152	2	25042806
Pubmed	MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.	STK3 FRY	5.68e-05	3	152	2	19327996
Pubmed	Genetic analysis of hook, a gene required for endocytic trafficking in drosophila.	HOOK1 HOOK2	5.68e-05	3	152	2	9927460
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	5.68e-05	3	152	2	10516026
Pubmed	RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.	DDX19B DDX19A	5.68e-05	3	152	2	25585691
Pubmed	The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.	HOOK1 HOOK2	5.68e-05	3	152	2	11238449
Pubmed	Deletions of N33, STK11 and TP53 are involved in the development of lymph node metastasis in larynx and pharynx carcinomas.	TUSC3 STK11	5.68e-05	3	152	2	17641416
Pubmed	LGI3 interacts with flotillin-1 to mediate APP trafficking and exosome formation.	APP FLOT1	5.68e-05	3	152	2	20461023
Pubmed	The role of flotillins in regulating aβ production, investigated using flotillin 1-/-, flotillin 2-/- double knockout mice.	APP FLOT1	5.68e-05	3	152	2	24465508
Pubmed	Hook2, a microtubule-binding protein, interacts with Par6α and controls centrosome orientation during polarized cell migration.	PARD6A HOOK2	5.68e-05	3	152	2	27624926
Pubmed	Decreased inward rectifier potassium current IK1 in dystrophin-deficient ventricular cardiomyocytes.	KCNJ2 UTRN	5.68e-05	3	152	2	27560040
Pubmed	Association of megacolon with a new dominant spotting gene (Dom) in the mouse.	SOX10 KRT71	5.68e-05	3	152	2	6512238
Pubmed	An investigation into the human serum "interactome".	ERVK-10 DCC PTPN5 ABCA6 CAMTA1 MOCOS	8.24e-05	162	152	6	15174051
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	NCAPD3 INTS1 ITPR1 FANCA NF1	9.69e-05	104	152	5	31240132
Pubmed	Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer.	CACNG2 KRT71	1.13e-04	4	152	2	9065835
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR3 ITPR1	1.13e-04	4	152	2	23413940
Pubmed	HIV-1 Tat interacts with and regulates the localization and processing of amyloid precursor protein.	APP FLOT1	1.13e-04	4	152	2	24312169
Pubmed	Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.	KCNJ2 KCNJ14	1.13e-04	4	152	2	15958527
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR3 ITPR1	1.13e-04	4	152	2	9607712
Pubmed	Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation.	STK11 FLOT1	1.13e-04	4	152	2	25157091
Pubmed	Pure distal 9p deletion in a female infant with cerebral palsy.	DOCK8 KANK1	1.13e-04	4	152	2	22876580
Pubmed	Perinatal lethality (ple): a mutation caused by integration of a transgene into distal mouse chromosome 15.	SOX10 KRT71	1.13e-04	4	152	2	2744761
Pubmed	The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation.	LRRK2 STK3	1.13e-04	4	152	2	20090955
Pubmed	KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.	KANK1 KANK4	1.13e-04	4	152	2	25961457
Pubmed	A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.	ABCA10 ABCA6	1.13e-04	4	152	2	25294155
Pubmed	Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization.	APP PTPN5	1.13e-04	4	152	2	21883219
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA10 ABCA9 ABCA6	1.19e-04	22	152	3	8894702
Pubmed	Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.	LGMN APP	1.88e-04	5	152	2	28826672
Pubmed	Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter.	CHAT APP	1.88e-04	5	152	2	17709753
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.88e-04	5	152	2	11401426
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA9 ABCA6	1.88e-04	5	152	2	12532264
Pubmed	Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.	GALNT12 MUC2	1.88e-04	5	152	2	12135769
Pubmed	The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.	STX3 FLOT1	1.88e-04	5	152	2	19815536
Pubmed	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	MYSM1 ARHGAP22	1.88e-04	5	152	2	21310492
Pubmed	Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans.	PTGER1 CREM	1.88e-04	5	152	2	21444662
Pubmed	Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth.	DCC APP	1.88e-04	5	152	2	22782894
Pubmed	cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.	ITPR1 GUCY2D	1.88e-04	5	152	2	26124274
Pubmed	LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity.	LRRK2 EGF	1.88e-04	5	152	2	25080504
Pubmed	Mouse erythroid cells express multiple putative RNA helicase genes exhibiting high sequence conservation from yeast to mammals.	DDX19A DDX3Y	1.88e-04	5	152	2	8144024
Pubmed	A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.	TUSC3 STK11 NF1 TOP3A	1.93e-04	65	152	4	27453043
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	NCAPD3 RAP1GDS1 SAMD8 TUSC3 HSPH1 INTS1 GALNT12 SCAMP2 FAT1 NF1 HOOK2 BCAM STX7 ADPGK	2.45e-04	1061	152	14	33845483
Pubmed	Isolated Gonadotropin-Releasing Hormone (GnRH) Deficiency	SOX10 SRA1 POLR3B	2.47e-04	28	152	3	20301509
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FNDC3B NCAPD3 IPO8 TUSC3 INTS1 SCAMP2 JMJD1C STX3 TXNDC15 WASHC5 TMEM65 BCAM STX7 FLOT1 ADPGK	2.68e-04	1203	152	15	29180619
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR3 ITPR1	2.81e-04	6	152	2	23463619
Pubmed	The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development.	RNF148 RNF150	2.81e-04	6	152	2	12435366
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR3 ITPR1	2.81e-04	6	152	2	25966694
Pubmed	Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures.	CACNG2 KRT71	2.81e-04	6	152	2	2289471
Pubmed	Small mammalian animal models of heart disease.	STK11 UTRN	2.81e-04	6	152	2	27679742
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR3 ITPR1	2.81e-04	6	152	2	20519450
Pubmed	Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.	CHAT APP	2.81e-04	6	152	2	19726636
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR3 ITPR1	2.81e-04	6	152	2	16844763
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	SOX10 LYST ITPR1 KRT71	2.86e-04	72	152	4	25917818
Pubmed	Dissection of behavior and psychiatric disorders using the mouse as a model.	APP RYR3 KCNAB1	3.36e-04	31	152	3	10767319
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DDX19B DDX19A NCAPD3 IPO8 SPG7 HSPBP1 STK3 HOOK1 CPSF1 ADPGK	3.52e-04	606	152	10	36538041
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNG2 KCNJ2 KCNJ14 SCNN1G KCNAB1	3.75e-04	139	152	5	16985003
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT1 FAT2	3.93e-04	7	152	2	16059920
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR3 ITPR1	3.93e-04	7	152	2	11860456
Pubmed	Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.	FANCA TOP3A	3.93e-04	7	152	2	21240188
Pubmed	NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.	SLC4A8 SLC9A2	3.93e-04	7	152	2	23677982
Pubmed	Regulation of NMDA receptor trafficking by amyloid-beta.	APP PTPN5	3.93e-04	7	152	2	16025111
Pubmed	Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.	STK11 NF1	3.93e-04	7	152	2	35425962
Pubmed	A novel hook-related protein family and the characterization of hook-related protein 1.	HOOK1 HOOK2	3.93e-04	7	152	2	15882442
Pubmed	The hairy ears (Eh) mutation is closely associated with a chromosomal rearrangement in mouse chromosome 15.	SOX10 KRT71	3.93e-04	7	152	2	2272507
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	ABCA10 ABCA9 ABCA6 KCNJ2	3.20e-04	98	151	4	chr17q24
Cytoband	1p32.1	MYSM1 HOOK1	4.75e-04	10	151	2	1p32.1
Cytoband	19p13.1	PTGER1 JAK3 OR10H2	5.41e-04	48	151	3	19p13.1
Cytoband	1q22	GON4L ERVK-7 SLC25A44	8.96e-04	57	151	3	1q22
Cytoband	9p24.3	DOCK8 KANK1	9.53e-04	14	151	2	9p24.3
Cytoband	10q11.2	RBP3 CHAT	9.53e-04	14	151	2	10q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	PTGER1 JAK3 STK11 USHBP1 OR10H2 KANK3 HOOK2 FEM1A TJP3	1.36e-03	797	151	9	chr19p13
Cytoband	17q24.3	ABCA6 KCNJ2	1.41e-03	17	151	2	17q24.3
GeneFamily	Ankyrin repeat domain containing\|KN motif and ankyrin repeat domain containing	KANK1 KANK3 KANK4	7.37e-07	4	104	3	623
GeneFamily	ATP binding cassette subfamily A	ABCA10 ABCA9 ABCA6	6.43e-05	14	104	3	805
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP	IPO8 SAMD8 GALNT12 GMEB2 PTGIS FRY ITSN2 MOCOS	6.23e-06	179	142	8	M8828
Coexpression	GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP	GMEB2 MST1R PRR14 KANK1 STX3 BCAM SLC2A12 TOP3A	1.40e-05	200	142	8	M8469
Coexpression	GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	SAMD8 DOCK8 COPS3 SRCAP JMJD1C ITPR1 STX7 UTRN	1.40e-05	200	142	8	M7505
Coexpression	YOSHIMURA_MAPK8_TARGETS_UP	SOX10 KIF27 DOCK8 GMEB2 PTGER1 ITPR1 FAT2 SLC9A2 HOOK1 KCNJ2 ST6GALNAC3 SLC28A1 SCNN1G GMPR RIMS1 STX7 MUC2 FEM1A DNAH9 CNGB1	1.98e-05	1281	142	20	M1884
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	FNDC3B RYR3 RNF150 FRY FAT1 KANK1 ST6GALNAC3 UTRN	2.13e-05	212	142	8	M39221
Coexpression	BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_DN	SPG7 INTS1 ATG4B CPSF1	2.32e-05	31	142	4	M4671
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	SCFD2 HSPH1 COPS3 APP FAT1 KANK1 ARHGEF10 ITSN2 CTNNBL1 KANK4 GMPR	2.99e-05	441	142	11	M172
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PDE1A SLC4A8 SAMD8 LRRK2 GALNT12 DCC LYST CACNG2 PTPN5 ANKRD44 TBC1D32 FRY FAT2 HOOK1 SORCS3 RIMS1 CAMTA1 MUC2	3.12e-05	1106	142	18	M39071
Coexpression	FAN_EMBRYONIC_CTX_OLIG	SOX10 PDE1A SAMD8 DOCK9 APP ANKRD44 ARHGAP22 FRY ARHGEF10 WASHC5 KCNJ2 ST6GALNAC3 KANK4 DIXDC1	6.34e-05	754	142	14	M39037
Coexpression	PTEN_DN.V1_UP	SRA1 TUSC3 RBP3 DCC SLC9A2 KANK3 CAMTA1	7.18e-05	186	142	7	M2787
Coexpression	DESCARTES_FETAL_THYMUS_VASCULAR_ENDOTHELIAL_CELLS	DOCK9 PKHD1L1 EGF ST6GALNAC3 KANK3 BCAM	8.15e-05	131	142	6	M40316
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 JMJD1C RNF150 FRY KANK1 EGF SETBP1 GMPR UTRN	1.23e-08	190	144	9	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 PDE1A DGKB RNF150 OR51E1 FRY GUCY1B1 KCNAB1 BCAM	1.54e-08	195	144	9	5dc874641ad9537e4c1369825c1fb0a59f12a83d
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	DOCK8 DGKB OR51E1 FRY GUCY1B1 KCNAB1 BCAM UTRN	6.80e-08	165	144	8	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PDE1A TUSC3 RNF150 FAT1 SLC9A2 SCNN1G BCAM SLC2A12	1.64e-07	185	144	8	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA10 ABCA9 ITPR1 RNF150 KANK1 EGF ABCA6 SLC2A12	2.45e-07	195	144	8	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 PDE1A RNF150 OR51E1 FRY GUCY1B1 KCNAB1 BCAM	2.65e-07	197	144	8	d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 PDE1A RNF150 OR51E1 FRY GUCY1B1 KCNAB1 BCAM	2.65e-07	197	144	8	68c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FILIP1 GALNT12 MYH14 SCNN1G BCAM UTRN MOCOS TJP3	2.75e-07	198	144	8	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZNF527 DGKB RNF150 HOOK1 ARHGEF10 KCNJ14 KCNAB1 MOCOS	2.97e-07	200	144	8	be83f442179ba4217d12f0458059586ff3130991
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY ARHGEF10 KANK3 BCAM	1.18e-06	166	144	7	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY ARHGEF10 KANK3 BCAM	1.18e-06	166	144	7	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 ITPR1 FRY USHBP1 KCNJ2 BCAM	1.55e-06	173	144	7	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 ITPR1 FRY USHBP1 KCNJ2 BCAM	1.55e-06	173	144	7	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY USHBP1 KANK3 BCAM	2.02e-06	180	144	7	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY USHBP1 KANK3 BCAM	2.02e-06	180	144	7	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH14 ST6GALNAC3 SCNN1G BCAM UTRN MOCOS TJP3	2.10e-06	181	144	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 DGKB OR51E1 FRY KANK4 KCNAB1 BCAM	2.10e-06	181	144	7	59527ad218e49386b04cabb97d53d2ed55a35961
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE1A PTGIS ABCA10 ABCA9 ABCA6 ST6GALNAC3 KCNAB1	2.18e-06	182	144	7	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NAPEPLD RYR3 FRY KANK1 ST6GALNAC3 SLC2A12 DNAH9	2.26e-06	183	144	7	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NAPEPLD RYR3 FRY KANK1 ST6GALNAC3 SLC2A12 DNAH9	2.26e-06	183	144	7	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 DOCK9 PAPOLB PKHD1L1 USHBP1 ST6GALNAC3 KANK3	2.51e-06	186	144	7	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 DGKB PTGIS GUCY1B1 KANK4 KCNAB1 RIMS1	2.60e-06	187	144	7	ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 LRRK2 DCC FAT1 KANK1 STX3 SLC28A1	2.60e-06	187	144	7	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	DOCK9 LRRK2 DCC PPP4R4 KANK1 KCNJ2 DUSP16	2.70e-06	188	144	7	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FILIP1 PDE1A SLC4A8 DGKB GUCY1B1 KCNAB1 BCAM	2.70e-06	188	144	7	a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	PDE1A TUSC3 RNF150 FAT1 SLC9A2 SCNN1G SLC2A12	2.70e-06	188	144	7	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE1A DOCK9 PKHD1L1 PTGIS OR1N1 ST6GALNAC3 SETBP1	2.79e-06	189	144	7	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PDE1A DOCK9 PKHD1L1 PTGIS ITPR1 ST6GALNAC3 SETBP1	2.79e-06	189	144	7	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	DOCK9 APP PKHD1L1 PTPN5 ST6GALNAC3 BCAM UTRN	3.10e-06	192	144	7	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PITPNM2 DOCK9 TUSC3 APP ARHGEF10 ST6GALNAC3 KANK3	3.21e-06	193	144	7	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	SAMD8 PRDM4 ITPR1 ARHGEF10 SETBP1 ITSN2 FEM1A	3.21e-06	193	144	7	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	APP PKHD1L1 PTGIS RYR3 ST6GALNAC3 KANK3 UTRN	3.21e-06	193	144	7	287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRDM4 LYST JMJD1C ITPR1 ANKRD44 SETBP1 STX7	3.32e-06	194	144	7	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A PTGER1 FAT1 SLC9A2 MYH14 SCNN1G TJP3	3.32e-06	194	144	7	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 DGKB PTGIS OR51E1 FRY KCNAB1 UTRN	3.32e-06	194	144	7	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 PKHD1L1 FRY USHBP1 KANK3 BCAM UTRN	3.32e-06	194	144	7	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 DGKB PTGIS OR51E1 FRY KCNAB1 UTRN	3.32e-06	194	144	7	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 KANK1 USHBP1 KANK3 KCNAB1 BCAM UTRN	3.32e-06	194	144	7	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CHAT DCC ABCA9 PTPN5 EGF ABCA6	3.32e-06	125	144	6	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	PDE1A PTGIS ABCA10 ABCA9 ANKRD44 ABCA6 SETBP1	3.43e-06	195	144	7	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A PTGER1 FAT1 SLC9A2 MYH14 SCNN1G TJP3	3.43e-06	195	144	7	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 PDE1A RNF150 FRY GUCY1B1 KCNAB1 BCAM	3.55e-06	196	144	7	ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TUSC3 APP FRY USHBP1 ARHGEF10 KANK3 BCAM	3.55e-06	196	144	7	a53caedd0103bd162b3aee8ab87b4442a5e0338f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FILIP1 PDE1A RNF150 FRY GUCY1B1 KCNAB1 BCAM	3.55e-06	196	144	7	6d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FILIP1 PDE1A DGKB OR51E1 FRY KCNAB1 BCAM	3.80e-06	198	144	7	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3 UTRN	3.80e-06	198	144	7	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	368C-Endothelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY USHBP1 KANK3 BCAM	3.80e-06	198	144	7	9a2c2201baee51581733e183065298a97eba4553
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 APP PKHD1L1 USHBP1 ST6GALNAC3 KANK3 BCAM	3.80e-06	198	144	7	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3 UTRN	3.80e-06	198	144	7	99d6a64f3410dae3019161feef20a8f06081a24b
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FILIP1 MYH14 SCNN1G BCAM UTRN MOCOS TJP3	3.92e-06	199	144	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FNDC3B DOCK8 ASB14 SRCAP ITPR1 UTRN ADPGK	3.92e-06	199	144	7	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 DOCK9 APP FRY USHBP1 ARHGEF10 GUCY1B1	4.06e-06	200	144	7	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FILIP1 MYH14 SCNN1G BCAM UTRN MOCOS TJP3	4.06e-06	200	144	7	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DGKB RNF150 HOOK1 ARHGEF10 KCNJ14 KCNAB1 MOCOS	4.06e-06	200	144	7	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 DOCK9 APP FRY USHBP1 ARHGEF10 KANK4	4.06e-06	200	144	7	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PITPNM2 DOCK9 APP FRY USHBP1 ARHGEF10 GUCY1B1	4.06e-06	200	144	7	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	MYH14 KANK4 SCNN1G BCAM UTRN MOCOS TJP3	4.06e-06	200	144	7	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	DGKB FRY KCNAB1 RIMS1 BCAM UTRN	1.37e-05	160	144	6	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HSPBP1 DCC FRY HOOK1 KANK3 SNAPC4	1.52e-05	163	144	6	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	PDE1A DOCK8 FRY KCNAB1 BCAM UTRN	1.99e-05	171	144	6	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA10 ABCA9 ITPR1 KANK1 EGF ABCA6	2.13e-05	173	144	6	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FILIP1 PTGER1 HOOK1 ARHGEF10 KCNJ2 MOCOS	2.20e-05	174	144	6	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A DOCK8 ITPR1 FAM153B TMEM65 GMPR	2.27e-05	175	144	6	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RYR3 OR51E1 FAT1 ST6GALNAC3 BCAM SLC2A12	2.27e-05	175	144	6	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3	2.35e-05	176	144	6	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3	2.35e-05	176	144	6	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 PKHD1L1 USHBP1 GUCY1B1 KANK3 UTRN	2.35e-05	176	144	6	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 MST1R ZBTB34 EGF GUCY2D TJP3	2.42e-05	177	144	6	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE1A SLC4A8 DGKB GUCY1B1 KCNAB1 BCAM	2.42e-05	177	144	6	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 MST1R ZBTB34 EGF GUCY2D TJP3	2.42e-05	177	144	6	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3	2.50e-05	178	144	6	4b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCell	facs-Heart-RA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCC KANK1 USHBP1 SCNN1G BCAM CNGB1	2.66e-05	180	144	6	174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY ARHGEF10 BCAM	2.66e-05	180	144	6	162cec1734e560c068cd61717e40e18dcf92308c
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 TUSC3 APP FRY ARHGEF10 BCAM	2.66e-05	180	144	6	33c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 DGKB PTGIS RNF150 GUCY1B1 KCNAB1	2.66e-05	180	144	6	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PITPNM2 DOCK9 TUSC3 APP ARHGEF10 ST6GALNAC3	2.75e-05	181	144	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTGER1 PPP4R4 RNF150 MDH1B DIXDC1 RIMS1	2.75e-05	181	144	6	ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 CHAT PKHD1L1 USHBP1 KANK3 GUCY2D	2.83e-05	182	144	6	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE1A TUSC3 PTGIS ABCA9 ABCA6 GUCY1B1	2.83e-05	182	144	6	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 LYST USHBP1 KANK3 BCAM UTRN	2.83e-05	182	144	6	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1A ARHGAP22 SLC9A2 CTNNBL1 DIXDC1 TOP3A	2.92e-05	183	144	6	ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB DCC PKHD1L1 RYR3 FAT1 DNAH9	3.01e-05	184	144	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH14 SCNN1G BCAM UTRN MOCOS TJP3	3.01e-05	184	144	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB DCC PKHD1L1 RYR3 FAT1 DNAH9	3.01e-05	184	144	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB DCC PKHD1L1 RYR3 FAT1 DNAH9	3.01e-05	184	144	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	PDE1A DGKB GUCY1B1 SETBP1 KCNAB1 RIMS1	3.01e-05	184	144	6	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FILIP1 RAP1GDS1 LRRK2 HOOK1 MYH14 KANK4	3.01e-05	184	144	6	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	SRCAP PTGIS FRY USHBP1 ST6GALNAC3 DIXDC1	3.10e-05	185	144	6	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3	3.10e-05	185	144	6	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USHBP1 KCNJ2 KANK3 KANK4 CNGB1 MOCOS	3.10e-05	185	144	6	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE1A DOCK9 APP PKHD1L1 ST6GALNAC3 KANK3	3.10e-05	185	144	6	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	PITPNM2 DOCK9 TUSC3 APP ST6GALNAC3 KANK3	3.10e-05	185	144	6	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	(5)_Pericytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FILIP1 PDE1A DGKB GUCY1B1 KCNAB1 BCAM	3.20e-05	186	144	6	acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell	(5)_Pericytes-(50)_Pericytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FILIP1 PDE1A DGKB GUCY1B1 KCNAB1 BCAM	3.20e-05	186	144	6	67b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DGKB OR51E1 FRY GUCY1B1 KANK4 BCAM	3.20e-05	186	144	6	1e3ab663e4756975db6d802b2c6c054a94a79393
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH14 SCNN1G HOOK2 UTRN MOCOS TJP3	3.20e-05	186	144	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	DOCK9 TUSC3 APP ARHGEF10 ST6GALNAC3 KANK3	3.20e-05	186	144	6	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 LYST USHBP1 KANK3 BCAM UTRN	3.20e-05	186	144	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 DGKB FAT1 KANK1 GUCY1B1 KCNAB1	3.30e-05	187	144	6	8ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	PITPNM2 DOCK9 TUSC3 APP ST6GALNAC3 KANK3	3.30e-05	187	144	6	54d7588172ac145ff5045ad9771636729ca3f0ca
Drug	yohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA	TUSC3 INTS1 GON4L APP JMJD1C DIP2A NF1 BCAM TOP3A	4.65e-06	194	146	9	1119_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	TUSC3 APP CRAT LYST CREM STX3 ARHGEF10 TOP3A TJP3	5.27e-06	197	146	9	6941_DN
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A	SRCAP PPP4R4 MST1R NF1 ARHGEF10 SETBP1 BCAM UTRN TOP3A	5.72e-06	199	146	9	3560_UP
Drug	CAS 298-57-7	SOX10 PTGER1 PTGIS RYR3 ITPR1 CACNG2	7.50e-06	73	146	6	CID000002761
Disease	Profound Mental Retardation	DOCK8 GON4L DCC FRY POLR3B NF1 SETBP1	4.09e-06	139	137	7	C0020796
Disease	Mental Retardation, Psychosocial	DOCK8 GON4L DCC FRY POLR3B NF1 SETBP1	4.09e-06	139	137	7	C0025363
Disease	Mental deficiency	DOCK8 GON4L DCC FRY POLR3B NF1 SETBP1	4.09e-06	139	137	7	C0917816
Disease	rosacea severity measurement	DGKB FANCA STK3 SORCS3 RIMS1 CAMTA1	6.63e-05	147	137	6	EFO_0009180
Disease	Neurodevelopmental Disorders	DOCK8 SRCAP ITPR1 SETBP1 RIMS1	7.51e-05	93	137	5	C1535926
Disease	Juvenile Myelomonocytic Leukemia	JAK3 NF1 SETBP1	8.98e-05	19	137	3	C0349639
Disease	corneal hysteresis	FNDC3B ABCA10 ABCA6	1.05e-04	20	137	3	EFO_0010066
Disease	disease free survival, microsatellite instability measurement, colorectal cancer	HSPH1 GALNT12	2.12e-04	5	137	2	EFO_0000409, EFO_0007054, MONDO_0005575
Disease	Pancytopenia	MYSM1 FANCA MOCOS	2.35e-04	26	137	3	C0030312
Disease	uterine fibroid	SCFD2 ITPR1 KANK1 GUCY1B1 KCNAB1 TOP3A	3.45e-04	199	137	6	EFO_0000731
Disease	juvenile myelomonocytic leukemia (is_implicated_in)	JAK3 NF1	4.43e-04	7	137	2	DOID:0050458 (is_implicated_in)
Disease	Colorectal Carcinoma	RBP3 GALNT12 DCC ABCA10 ABCA9 STK11 FAT1 NF1 ABCA6 SETBP1 SCNN1G	4.51e-04	702	137	11	C0009402
Disease	gestational age	ABCA9 ANKRD44 KCNAB1 CAMTA1 UTRN	4.74e-04	138	137	5	EFO_0005112
Disease	intermediate density lipoprotein measurement	ABCA10 JMJD1C ABCA6 BCAM	7.35e-04	87	137	4	EFO_0008595
Disease	Spastic Paraplegia	SPG7 LYST	7.54e-04	9	137	2	C0037772
Disease	transient cerebral ischemia (biomarker_via_orthology)	CREM ITPR1 PTPN5 NF1 DUSP16	8.50e-04	157	137	5	DOID:224 (biomarker_via_orthology)
Disease	Inherited neuropathies	SPG7 ITPR1 WASHC5	8.53e-04	40	137	3	C0598589
Disease	concentration of large LDL particles measurement	ABCA10 ABCA6 BCAM	1.13e-03	44	137	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	ABCA10 ABCA6 BCAM	1.13e-03	44	137	3	EFO_0022225
Disease	response to cisplatin, response to antineoplastic agent	HAO1 PTPN5	1.15e-03	11	137	2	GO_0072718, GO_0097327
Disease	reticulocyte count	PITPNM2 FNDC3B COPS3 GMEB2 JMJD1C FAT1 EGF HOOK1 KANK3 SETBP1 GMPR HOOK2 STX7	1.19e-03	1045	137	13	EFO_0007986
Disease	esophagus squamous cell carcinoma (is_implicated_in)	DCC FANCA FAT1	1.20e-03	45	137	3	DOID:3748 (is_implicated_in)
Disease	Adenoid Cystic Carcinoma	SRCAP JMJD1C FANCA FAT1	1.24e-03	100	137	4	C0010606
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK1 HOOK2	1.37e-03	12	137	2	DOID:11726 (implicated_via_orthology)
Disease	hair colour measurement, hair morphology measurement	SPG7 FANCA	1.37e-03	12	137	2	EFO_0007821, EFO_0007822
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	FNDC3B KIF27 FANCA MST1R ANKRD44 SETBP1 CAMTA1	1.60e-03	364	137	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	triglycerides to total lipids in medium LDL percentage	JMJD1C ABCA6 BCAM	1.64e-03	50	137	3	EFO_0022334
Disease	free cholesterol in large LDL measurement	JMJD1C ABCA6 BCAM	1.73e-03	51	137	3	EFO_0022176
Disease	cholesterol to total lipids in small VLDL percentage	JMJD1C ABCA6 BCAM	1.73e-03	51	137	3	EFO_0022242
Disease	phospholipids in IDL measurement	ABCA10 ABCA6 BCAM	1.83e-03	52	137	3	EFO_0022164
Disease	chromosome-type aberration frequency	STX3 SLC2A12	1.88e-03	14	137	2	EFO_0009861
Disease	age at last pregnancy measurement	MST1R SORCS3	1.88e-03	14	137	2	EFO_0009440
Disease	response to selective serotonin reuptake inhibitor, openness measurement	TUSC3 UTRN	1.88e-03	14	137	2	EFO_0005658, EFO_0007914
Disease	Colorectal Neoplasms	GALNT12 DCC ABCA10 ABCA9 FAT1 ABCA6	1.91e-03	277	137	6	C0009404
Disease	triglycerides to total lipids in very large VLDL percentage	JMJD1C ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022340
Disease	cholesteryl esters to total lipids in very large VLDL percentage	JMJD1C ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022258
Disease	hair morphology measurement	KANK1 KRT71 OSBPL11	2.04e-03	54	137	3	EFO_0007821
Disease	cholesterol to total lipids in very large VLDL percentage	JMJD1C ABCA6 BCAM	2.04e-03	54	137	3	EFO_0022244
Disease	Carcinoma, Granular Cell	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0205644
Disease	Adenocarcinoma, Tubular	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0205642
Disease	Carcinoma, Cribriform	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0205643
Disease	Adenocarcinoma, Basal Cell	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0205641
Disease	Adenocarcinoma	PTGER1 STK11 EGF MUC2	2.13e-03	116	137	4	C0001418
Disease	colorectal cancer (is_implicated_in)	GALNT12 DCC FAT1 CTNNBL1	2.48e-03	121	137	4	DOID:9256 (is_implicated_in)
Disease	triglycerides to total lipids in small VLDL percentage	JMJD1C ABCA6 BCAM	2.51e-03	58	137	3	EFO_0022338
Disease	cholesterol in IDL measurement	JMJD1C ABCA6 BCAM	2.51e-03	58	137	3	EFO_0021899
Disease	triglycerides to total lipids in small LDL percentage	JMJD1C ABCA6 BCAM	2.63e-03	59	137	3	EFO_0022337
Disease	free cholesterol to total lipids in very large VLDL percentage	JMJD1C ABCA6 BCAM	2.63e-03	59	137	3	EFO_0022289
Disease	total lipids in IDL	JMJD1C ABCA6 BCAM	2.76e-03	60	137	3	EFO_0022161
Disease	schizophrenia, sex interaction measurement	ABCA9 ABCA6 MOCOS	2.76e-03	60	137	3	EFO_0008343, MONDO_0005090
Disease	breast carcinoma	SCFD2 FNDC3B NAPEPLD TMEM69 SCAMP2 JMJD1C ITPR1 USHBP1 SETBP1 SLC25A44 SORCS3 HOOK2	2.89e-03	1019	137	12	EFO_0000305
Disease	free cholesterol in IDL measurement	JMJD1C ABCA6 BCAM	2.89e-03	61	137	3	EFO_0022181
Disease	Idiopathic hypogonadotropic hypogonadism	SRA1 POLR3B	3.12e-03	18	137	2	C0342384
Disease	Bone marrow hypocellularity	MYSM1 FANCA	3.12e-03	18	137	2	C1855710
Disease	triglycerides to total lipids in IDL percentage	JMJD1C ABCA6 BCAM	3.17e-03	63	137	3	EFO_0022329
Disease	triglycerides to total lipids in medium VLDL percentage	JMJD1C ABCA6 BCAM	3.17e-03	63	137	3	EFO_0022335
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	JMJD1C CREM EGF GMPR	3.31e-03	131	137	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	JMJD1C CREM EGF GMPR	3.31e-03	131	137	4	C4552091
Disease	Juvenile arthritis	JMJD1C CREM EGF GMPR	3.31e-03	131	137	4	C3495559
Disease	Juvenile psoriatic arthritis	JMJD1C CREM EGF GMPR	3.31e-03	131	137	4	C3714758
Disease	Liver Cirrhosis, Experimental	LGMN TUSC3 HAO1 APP FRY FAT1 KANK1 EGF DUSP16 TMEM65	3.37e-03	774	137	10	C0023893
Disease	unipolar depression, mood disorder	DCC MST1R SORCS3 CAMTA1	3.58e-03	134	137	4	EFO_0003761, EFO_0004247
Disease	Juvenile-Onset Still Disease	JMJD1C CREM EGF GMPR	3.68e-03	135	137	4	C0087031
Disease	smoking behaviour measurement	SCFD2 HAO1 DCC SORCS3 CAMTA1	3.86e-03	222	137	5	EFO_0005671
Disease	apolipoprotein B measurement	DDX19B ABCA10 ABCA9 PPP4R4 NF1 HOOK1 ABCA6 KANK4 BCAM	3.89e-03	663	137	9	EFO_0004615
Disease	triglycerides to total lipids in very small VLDL percentage	JMJD1C ABCA6 BCAM	4.10e-03	69	137	3	EFO_0022341
Disease	disease	SETBP1 BCAM	4.24e-03	21	137	2	EFO_0000408
Disease	Malignant neoplasm of breast	FNDC3B OR1N1 SLC9A2 TXNDC15 NF1 EGF HOOK1 SETBP1 ITSN2 SLC28A1 OSBPL11 DNAH9	4.39e-03	1074	137	12	C0006142
Disease	mitochondrial DNA measurement	DGKB JMJD1C STK11 USHBP1 ST6GALNAC3 TOP3A	4.39e-03	328	137	6	EFO_0006312

Protein segments in the cluster

Peptide	Gene	Start	Entry
HIMEAQMEQLRGSIE	USHBP1	291	Q8N6Y0
MMSEHDLADVVQIAV	BANP	1	Q8N9N5
DLVVLSGLHMMEGQS	ADPGK	256	Q9BRR6
QEEGMVISHMAVSGV	ARHGEF10	1106	O15013
DDIQVNMMTLAEHII	CAMTA1	1391	Q9Y6Y1
DLNDIIQEMHVVATM	CTNNBL1	116	Q8WYA6
EQAITTPAMAVSHIM	COPS3	206	Q9UNS2
HSVMEELTSVIGINM	ABCA10	106	Q8WWZ4
QHIGNTLGSMIEEEM	TBC1D32	61	Q96NH3
QQLVETHMARVEAML	APP	451	P05067
EIATNHSVMEQLMSV	ABCA9	191	Q8IUA7
EQGISSLMERLHVME	DIXDC1	541	Q155Q3
IIEITTNHPVMEELM	ABCA6	186	Q8N139
TNHPVMEELMSVTAI	ABCA6	191	Q8N139
SIMIQDLDITVMVFH	CRAT	401	P43155
LALAAQSGHTEIMEM	ASB14	221	A6NK59
VHIAMDNTVVMEEIR	ATG4B	166	Q9Y4P1
MATPDVSVHMEEVVV	GMEB2	1	Q9UKD1
MIGDILAAELSHMQA	ITSN2	1286	Q9NZM3
STMVQEFVHLGAIDM	JAK3	596	P52333
HTPIIVMITNIEEMN	PTPN5	391	P54829
ASLVTMGIVNLNIHM	SLC2A12	356	Q8TD20
VILEGMVEATAMTTQ	KCNJ2	296	P63252
MNVIDHVRDMAAAGL	ANAPC7	1	Q9UJX3
SFIIAEMVGVLAVHM	CACNG2	186	Q9Y698
MVMIEEFKQGLAITH	PAPOLB	336	Q9NRJ5
TVMESDPVAHMIGVI	FAT1	1366	Q14517
MGQHNLTVLTEFILM	OR8K5	1	Q8NH50
TEAQHMVGAMRLAVT	FAM189A1	506	O60320
IMETISGDRLTHQIM	DCC	996	P43146
MLGLNHTSMSEFILV	OR10H2	1	O60403
QMVSDLSQVTVHLMA	KIAA0100	1381	Q14667
RFVVHITDVLAVSMM	INTS1	536	Q8N201
AVIMVMHSVLLGGEE	GUCY2D	241	Q02846
MRSIHGVGELMTQVV	ITPR1	931	Q14643
MTLEESVQHVVMEAI	HOOK2	136	Q96ED9
SVQHVVMEAIQELMT	HOOK2	141	Q96ED9
TPMEEIVRAMTHVIN	KCNAB1	216	Q14722
SMVQMTFLDDVVHSL	JMJD1C	236	Q15652
MGEEHLFSVEQITAM	HSPH1	106	Q92598
VVIMSAEGHVTMFLL	CPSF1	656	Q10570
GHQRAIMAHMTVEEI	FLOT1	106	O75955
EVMSLLEMGNAARHT	KIF27	181	Q86VH2
GFSHEEIISMLRMVS	MYH14	356	Q7Z406
FTVMETDPVNHMVGV	FAT2	1356	Q9NYQ8
IHSLSGMESTVLLAM	OR51E1	106	Q8TCB6
HIMVSMAIGVRLQVQ	MUC2	491	Q02817
NLVIEMVLSTDMSGH	PDE1A	321	P54750
HDVEMVGQLVGIMVV	PTGER1	291	P34995
AMQRMAHVDGELATV	HAO1	81	Q9UJM8
TALMLAVSHGRIDMV	KANK1	1236	Q14678
SLEGAMDSVLHTLQM	LRRK2	581	Q5S007
SHTSVVGMRNVTMAI	MOCOS	151	Q96EN8
ICHLALDMMEIAGQV	GUCY1B1	496	Q02153
IMTGHEECVQMLLEQ	ANKRD44	711	Q8N8A2
MVTLTGEKVDVHIMT	PITPNM2	1031	Q9BZ72
VILEGMVEATAMTTQ	KCNJ14	301	Q9UNX9
DTHASEMAIFLMGVV	OR2D2	191	Q9H210
SHLTEEERNIIMAVM	RIMS1	26	Q86UR5
VTDMMVANSHNLIVT	PARD6A	231	Q9NPB6
HKAMLMAQAITGVVL	ERVK-10	521	P87889
HKAMLMAQAITGVVL	ERVK-19	521	Q9YNA8
HKAMLMAQAITGVVL	ERVK-21	521	P62683
HKAMLMAQAITGVVL	ERVK-24	521	P63145
HKAMLMAQAITGVVL	ERVK-6	521	Q7LDI9
HKAMLMAQAITGVVL	ERVK-7	521	P63130
HKAMLMAQAITGVVL	ERVK-8	521	P62685
HKAMLMAQAITGVVL	ERVK-9	521	P63126
HKAMLMAQAITGVVL	HERVK_113	521	P62684
HEELALQMVVSTGMV	DOCK8	961	Q8NF50
AVETVVNMLMPHITQ	DOCK9	996	Q9BZ29
ITESQHMLVAEIMVS	EGF	816	P01133
SITVGNTTMHVMKDL	FNDC3B	911	Q53EP0
MVFEHTGNIPVTVME	FANCA	556	O15360
GMVVVDELHMLGDSH	POLQ	211	O75417
MAHEMIGTQIVTERL	DUSP16	1	Q9BY84
EGHQVALLSGEMMVE	DDX19B	356	Q9UMR2
IMNALIEAGAHMDAT	FEM1A	596	Q9BSK4
VTMATSEHVIMQNEA	RAP1GDS1	496	P52306
LMGAMQLIEDFSTHV	GON4L	756	Q3T8J9
LNSTEMHLIIVRGMN	CC2D1B	696	Q5T0F9
SSELENIISQMMHVA	DGKB	171	Q9Y6T7
CIAVEAGMDTLIMHL	GALNT12	506	Q8IXK2
VLHLLSVDVSTAEMM	LYST	331	Q99698
TELMMVIAQENLGAH	MDH1B	101	Q5I0G3
MLAISHGRQDMVATL	KANK3	701	Q6NY19
MLGVSHDREDMVQAL	KANK4	901	Q5T7N3
RHIEIQQMESTMASI	DNAH9	1261	Q9NYC9
NIAVIFMTEMVVDHS	FRY	1641	Q5TBA9
IMTLEESVQHVVMTA	HOOK1	141	Q9UJC3
ESVQHVVMTAIQELM	HOOK1	146	Q9UJC3
GVLTSVMNRMHVVSV	DIP2A	566	Q14689
EHTIMAGNVVTGEMV	GMPR	151	P36959
GHQVALLSGEMMVEQ	DDX19A	356	Q9NUU7
HIENFSDIDMGEIIM	DDX3Y	176	O15523
AEMQGSELQVTMHDT	BCAM	81	P50895
MTMETVESQHDGSIT	CREM	1	Q03060
FGMPIHSIIEVLNMV	PRAMEF8	186	Q5VWM4
EIETAMVTSIGMHLT	SCNN1G	346	P51170
QTVSEEATGVHMMQV	FAM153B	266	P0C7A2
TVSEEATGVHMMQVD	FAM153B	301	P0C7A2
VVMETDHIASRVNGM	PRDM4	266	Q9UKN5
HLVEVREMMSHAEGQ	OSBPL11	216	Q9BXB4
VEDKTVMAMGILHTI	IPO8	601	O15397
VMAMGILHTIDTILT	IPO8	606	O15397
IGLTMAVLHVTAMFN	OR10J5	151	Q8NHC4
HINEMMVFVLGGTVL	OR1N1	191	Q8NGS0
ITMPHAGVEDIVAIM	RNF150	156	Q9ULK6
MGMVQQLVALVRTEH	HSPBP1	271	Q9NZL4
MMELTAHQSSVGSVL	UTRN	356	P46939
LHVAGVEMQLTAAMS	PPP4R4	101	Q6NUP7
TSFIMVIVHERVPDM	SAMD8	166	Q96LT4
IMEGELQAREDVIHM	FILIP1	86	Q7Z7B0
DGALVEAGMETHIMT	SORCS3	656	Q9UPU3
DLGMMIHEQGDVIDS	STX7	191	O15400
LHLEEMGVSEEMQAR	PTGIS	261	Q16647
VLAVVLEDVMAVHMV	PRR14	51	Q9BWN1
IVTVIMGMGVAFHLE	TMEM69	186	Q5SWH9
EEDVGRMTMIRVVSH	ST6GALNAC3	116	Q8NDV1
NHSLAISVIMMVVAG	SCAMP2	256	O15127
DVMVNMIALTALHTE	SCFD2	306	Q8WU76
ELMSVGMDTFIHRID	STK11	16	Q15831
ITVPIDVVSQHLMMQ	SLC25A44	126	Q96H78
IGRSMATIMTDEIFH	SLC4A8	356	Q2Y0W8
LLVEMDGMGTTDHVI	SPG7	436	Q9UQ90
TLATGHFMSVINILM	SRCAP	881	Q6ZRS2
MNHTMVTEFVLLGLS	OR6C3	1	Q9NZP0
GEMLDNIELNVMHTV	STX3	226	Q13277
HKAMLMAQAITGVVL	ERVK-9	521	P63128
TIMEGTSLVQHLMTV	ARHGAP22	326	Q7Z5H3
TVMAITGMAIDNHLL	CHAT	611	P28329
HQMLSVILMLEVGEG	NCAPD3	301	P42695
HSQGMLDESELMVQL	CNGB1	926	Q14028
FGMPIHSIIEVLNMV	PRAMEF7	186	Q5VXH5
ILSGMMGDTILTHFV	SLC25A14	226	O95258
IEHNSTMLESDLGTM	STK3	351	Q13188
SHIILVLNAAITMGM	TUSC3	281	Q13454
LTHAISIFTEGILMM	WASHC5	676	Q12768
QEVLSMMGEFLVAHV	RBP3	141	P10745
IKHAIEMAETGMIST	SLC9A2	561	Q9UBY0
VAVMISNLKGMEILH	RNF148	151	Q8N7C7
HETVMEVMVNVLGTE	RYR3	2066	Q15413
LHERGAAEMVLQMIS	RYR3	3621	Q15413
LMVDHVTEVSQWMVG	SRA1	171	Q9HD15
VLGLDTQGDHMVMLS	TXNDC15	81	Q96J42
VDIGEISHEVMSNME	SOX10	276	P56693
EHLGQASIETMMLNL	NF1	981	P21359
IVQMIGTEEHVMAAF	POLR3B	251	Q9NW08
EHEMVMIDVDGSLTG	PKHD1L1	2791	Q86WI1
ADMTLSEVHVVMTGG	SLC28A1	331	O00337
NVTMVMTSVSGHLLA	TOP3A	81	Q13472
LDNAIMIVAGTHIEM	TMEM65	131	Q6PI78
MIVAGTHIEMSIGII	TMEM65	136	Q6PI78
DHIVMVNGVSMENAT	TJP3	56	O95049
MLTQLVQEMRVGSHI	SNAPC4	356	Q5SXM2
SQDTIMATIEAVIHM	SETBP1	1501	Q9Y6X0
VAHMGTMDGRILQVE	MST1R	461	Q04912
ASEMGLDSRMEIHTV	ZBTB34	481	Q8NCN2
EISQEMVMERLASHG	ZNF527	106	Q8NB42
IQSHISDMSVILSMD	KRT71	276	Q3SY84
IHRNGIPDEQIVVMM	LGMN	56	Q99538
GHATVMVEMDELIFL	NAPEPLD	131	Q6IQ20
IMDLHAHVSMAEVIG	MYSM1	586	Q5VVJ2