| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | NPC1 HCAR2 ABCA1 TRPA1 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 ADGRG1 ADGRL1 OR4D6 OR2S2 PTAFR ACKR4 GRM8 IL18R1 CHRM2 OR10R2 OR2B11 HCAR3 TAS2R8 TAS2R13 OR10AG1 OR10J5 FCER1A P2RY4 ACKR3 KIR3DL3 OR52E5 LRP5 HRH4 OR1K1 ADGRF4 SEMA6A C5AR1 TAS2R31 TAS2R43 IL17RD ADGRF1 GPR176 GPR45 OR2H2 SORL1 OR2A2 | 1.11e-22 | 1353 | 124 | 46 | GO:0004888 |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 ADGRG1 ADGRL1 OR4D6 OR2S2 PTAFR ACKR4 GRM8 CHRM2 OR10R2 OR2B11 HCAR3 TAS2R8 TAS2R13 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 ADGRF4 C5AR1 TAS2R31 TAS2R43 ADGRF1 GPR176 GPR45 OR2H2 OR2A2 | 4.81e-20 | 884 | 124 | 36 | GO:0004930 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | ANO4 CACNA1D ANO2 TMEM144 ABCA1 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 ANO5 APOL1 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLCO5A1 CLCN3 KCNT2 CLCN7 SLC24A2 SLC16A14 SLC28A1 NIPAL1 LRP5 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 SLC38A8 SLC35A5 SLC23A3 | 7.21e-17 | 1180 | 124 | 37 | GO:0022857 |
| GeneOntologyMolecularFunction | transporter activity | NPC1 ANO4 CACNA1D ANO2 TMEM144 ABCA1 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 ANO5 APOL1 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLCO5A1 CLCN3 KCNT2 CLCN7 SLC24A2 SLC16A14 SLC28A1 NIPAL1 LRP5 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 SLC38A8 SLC35A5 SLC23A3 | 1.87e-16 | 1289 | 124 | 38 | GO:0005215 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | ANO4 CACNA1D ANO2 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 ANO5 APOL1 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 CLCN7 SLC24A2 SLC28A1 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.22e-13 | 758 | 124 | 27 | GO:0015318 |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | ABCA1 ATP7A SLC38A5 TCIRG1 ABCC5 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLCO5A1 CLCN3 CLCN7 SLC24A2 SLC16A14 SLC28A1 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 SLC35A5 | 1.90e-13 | 477 | 124 | 22 | GO:0022804 |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | ANO4 CACNA1D ANO2 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ANO5 APOL1 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 CLCN7 SLC24A2 SLC28A1 NIPAL1 KCNQ3 SLC13A5 ATP2A1 ATP2A2 ATP2B3 | 1.62e-11 | 793 | 124 | 25 | GO:0015075 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 SLC6A2 SLC38A1 SLC6A3 KCNT2 SLC24A2 SLC28A1 NIPAL1 KCNQ3 SLC13A5 ATP2A1 ATP2A2 ATP2B3 | 6.20e-10 | 465 | 124 | 18 | GO:0046873 |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | SLC38A5 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLCO5A1 CLCN3 CLCN7 SLC24A2 SLC16A14 SLC28A1 SLC13A5 SLC35A5 | 4.60e-09 | 296 | 124 | 14 | GO:0015291 |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 SLC6A2 SLC38A1 SLC6A3 KCNT2 SLC24A2 SLC28A1 NIPAL1 KCNQ3 SLC13A5 ATP2A1 ATP2A2 ATP2B3 | 1.11e-08 | 627 | 124 | 19 | GO:0022890 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 SLC6A2 SLC38A1 SLC6A3 KCNT2 SLC24A2 SLC28A1 NIPAL1 KCNQ3 SLC13A5 ATP2A1 ATP2A2 ATP2B3 | 2.79e-08 | 664 | 124 | 19 | GO:0008324 |
| GeneOntologyMolecularFunction | inorganic anion transmembrane transporter activity | 1.15e-07 | 171 | 124 | 10 | GO:0015103 | |
| GeneOntologyMolecularFunction | active monoatomic ion transmembrane transporter activity | ATP7A SLC38A5 TCIRG1 SLC6A2 SLC38A1 SLC6A3 SLC24A2 SLC28A1 SLC13A5 ATP2A1 ATP2A2 ATP2B3 | 3.91e-07 | 301 | 124 | 12 | GO:0022853 |
| GeneOntologyMolecularFunction | ATPase-coupled transmembrane transporter activity | 3.96e-07 | 109 | 124 | 8 | GO:0042626 | |
| GeneOntologyMolecularFunction | olfactory receptor activity | OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 OR10AG1 OR10J5 OR52E5 OR1K1 OR2H2 OR2A2 | 4.85e-07 | 431 | 124 | 14 | GO:0004984 |
| GeneOntologyMolecularFunction | chloride transmembrane transporter activity | 1.13e-06 | 125 | 124 | 8 | GO:0015108 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | HCN4 HCN1 SLC38A5 SLC6A2 SLC38A1 SLC6A3 SLC24A2 SLC28A1 SLC13A5 | 1.23e-06 | 171 | 124 | 9 | GO:0015081 |
| GeneOntologyMolecularFunction | monoatomic anion transmembrane transporter activity | 4.66e-06 | 151 | 124 | 8 | GO:0008509 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | ANO4 CACNA1D ANO2 TRPA1 HCN4 HCN1 ANO5 APOL1 CLCN3 KCNT2 CLCN7 SLC24A2 KCNQ3 | 5.71e-06 | 459 | 124 | 13 | GO:0005216 |
| GeneOntologyMolecularFunction | gated channel activity | ANO4 CACNA1D ANO2 TRPA1 HCN4 HCN1 ANO5 CLCN3 KCNT2 CLCN7 KCNQ3 | 7.65e-06 | 334 | 124 | 11 | GO:0022836 |
| GeneOntologyMolecularFunction | nucleotide receptor activity | 9.50e-06 | 22 | 124 | 4 | GO:0016502 | |
| GeneOntologyMolecularFunction | purinergic nucleotide receptor activity | 9.50e-06 | 22 | 124 | 4 | GO:0001614 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | SLC38A5 ABCC5 SLC7A6 SLCO1B7 SLC38A1 SLCO5A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 1.49e-05 | 293 | 124 | 10 | GO:0008514 |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 1.56e-05 | 178 | 124 | 8 | GO:0015399 | |
| GeneOntologyMolecularFunction | chloride channel activity | 1.59e-05 | 86 | 124 | 6 | GO:0005254 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 1.83e-05 | 182 | 124 | 8 | GO:0005244 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 1.98e-05 | 184 | 124 | 8 | GO:0022832 | |
| GeneOntologyMolecularFunction | bitter taste receptor activity | 2.23e-05 | 27 | 124 | 4 | GO:0033038 | |
| GeneOntologyMolecularFunction | channel activity | ANO4 CACNA1D ANO2 TRPA1 HCN4 HCN1 ANO5 APOL1 CLCN3 KCNT2 CLCN7 SLC24A2 KCNQ3 | 2.37e-05 | 525 | 124 | 13 | GO:0015267 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | ANO4 CACNA1D ANO2 TRPA1 HCN4 HCN1 ANO5 APOL1 CLCN3 KCNT2 CLCN7 SLC24A2 KCNQ3 | 2.42e-05 | 526 | 124 | 13 | GO:0022803 |
| GeneOntologyMolecularFunction | P-type calcium transporter activity | 3.72e-05 | 11 | 124 | 3 | GO:0005388 | |
| GeneOntologyMolecularFunction | nicotinic acid receptor activity | 3.83e-05 | 2 | 124 | 2 | GO:0070553 | |
| GeneOntologyMolecularFunction | ATPase-coupled monoatomic cation transmembrane transporter activity | 4.15e-05 | 62 | 124 | 5 | GO:0019829 | |
| GeneOntologyMolecularFunction | symporter activity | 4.24e-05 | 150 | 124 | 7 | GO:0015293 | |
| GeneOntologyMolecularFunction | monoatomic anion channel activity | 4.44e-05 | 103 | 124 | 6 | GO:0005253 | |
| GeneOntologyMolecularFunction | carboxylic acid transmembrane transporter activity | SLC38A5 SLC7A6 SLCO1B7 SLC38A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 4.59e-05 | 207 | 124 | 8 | GO:0046943 |
| GeneOntologyMolecularFunction | organic acid transmembrane transporter activity | SLC38A5 SLC7A6 SLCO1B7 SLC38A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 4.75e-05 | 208 | 124 | 8 | GO:0005342 |
| GeneOntologyMolecularFunction | taste receptor activity | 5.04e-05 | 33 | 124 | 4 | GO:0008527 | |
| GeneOntologyMolecularFunction | P-type transmembrane transporter activity | 7.15e-05 | 36 | 124 | 4 | GO:0140358 | |
| GeneOntologyMolecularFunction | P-type ion transporter activity | 7.15e-05 | 36 | 124 | 4 | GO:0015662 | |
| GeneOntologyMolecularFunction | immune receptor activity | 7.75e-05 | 165 | 124 | 7 | GO:0140375 | |
| GeneOntologyMolecularFunction | norepinephrine:sodium symporter activity | 1.14e-04 | 3 | 124 | 2 | GO:0005334 | |
| GeneOntologyMolecularFunction | solute:sodium symporter activity | 1.50e-04 | 81 | 124 | 5 | GO:0015370 | |
| GeneOntologyMolecularFunction | organic cation transmembrane transporter activity | 1.68e-04 | 83 | 124 | 5 | GO:0015101 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 2.05e-04 | 193 | 124 | 7 | GO:0015276 | |
| GeneOntologyMolecularFunction | antiporter activity | 2.24e-04 | 138 | 124 | 6 | GO:0015297 | |
| GeneOntologyMolecularFunction | dopamine:sodium symporter activity | 2.28e-04 | 4 | 124 | 2 | GO:0005330 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 2.33e-04 | 197 | 124 | 7 | GO:0022834 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated channel activity | 2.47e-04 | 20 | 124 | 3 | GO:0141147 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated chloride channel activity | 2.47e-04 | 20 | 124 | 3 | GO:0005229 | |
| GeneOntologyMolecularFunction | intramembrane lipid transporter activity | 2.82e-04 | 51 | 124 | 4 | GO:0140303 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 3.63e-04 | 151 | 124 | 6 | GO:0015085 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | 3.76e-04 | 152 | 124 | 6 | GO:0022843 | |
| GeneOntologyMolecularFunction | phospholipid scramblase activity | 3.78e-04 | 23 | 124 | 3 | GO:0017128 | |
| GeneOntologyMolecularFunction | carbohydrate derivative transmembrane transporter activity | 4.95e-04 | 59 | 124 | 4 | GO:1901505 | |
| GeneOntologyMolecularFunction | nucleobase-containing compound transmembrane transporter activity | 4.95e-04 | 59 | 124 | 4 | GO:0015932 | |
| GeneOntologyMolecularFunction | G protein-coupled acetylcholine receptor activity | 7.87e-04 | 7 | 124 | 2 | GO:0016907 | |
| GeneOntologyMolecularFunction | solute:monoatomic cation symporter activity | 8.85e-04 | 119 | 124 | 5 | GO:0015294 | |
| GeneOntologyMolecularFunction | L-amino acid transmembrane transporter activity | 9.98e-04 | 71 | 124 | 4 | GO:0015179 | |
| GeneOntologyMolecularFunction | intracellularly ligand-gated monoatomic ion channel activity | 1.11e-03 | 33 | 124 | 3 | GO:0005217 | |
| GeneOntologyMolecularFunction | phospholipid transporter activity | 1.17e-03 | 74 | 124 | 4 | GO:0005548 | |
| GeneOntologyMolecularFunction | L-glutamine transmembrane transporter activity | 1.34e-03 | 9 | 124 | 2 | GO:0015186 | |
| GeneOntologyMolecularFunction | lipid transporter activity | 1.42e-03 | 196 | 124 | 6 | GO:0005319 | |
| GeneOntologyMolecularFunction | intracellularly cAMP-activated cation channel activity | 1.67e-03 | 10 | 124 | 2 | GO:0005222 | |
| GeneOntologyMolecularFunction | glycine transmembrane transporter activity | 1.67e-03 | 10 | 124 | 2 | GO:0015187 | |
| GeneOntologyMolecularFunction | ATPase-coupled inorganic anion transmembrane transporter activity | 1.67e-03 | 10 | 124 | 2 | GO:0043225 | |
| GeneOntologyMolecularFunction | cargo receptor activity | 1.95e-03 | 85 | 124 | 4 | GO:0038024 | |
| GeneOntologyMolecularFunction | voltage-gated chloride channel activity | 2.03e-03 | 11 | 124 | 2 | GO:0005247 | |
| GeneOntologyMolecularFunction | amide transmembrane transporter activity | 2.25e-03 | 42 | 124 | 3 | GO:0042887 | |
| GeneOntologyMolecularFunction | monoamine transmembrane transporter activity | 2.42e-03 | 12 | 124 | 2 | GO:0008504 | |
| GeneOntologyMolecularFunction | intracellularly cyclic nucleotide-activated monoatomic cation channel activity | 2.85e-03 | 13 | 124 | 2 | GO:0005221 | |
| GeneOntologyMolecularFunction | G protein-coupled neurotransmitter receptor activity | 2.85e-03 | 13 | 124 | 2 | GO:0099528 | |
| GeneOntologyMolecularFunction | cyclic nucleotide-activated monoatomic ion channel activity | 2.85e-03 | 13 | 124 | 2 | GO:0043855 | |
| GeneOntologyMolecularFunction | G protein-coupled purinergic nucleotide receptor activity | 2.85e-03 | 13 | 124 | 2 | GO:0045028 | |
| GeneOntologyMolecularFunction | cytokine receptor activity | 3.15e-03 | 97 | 124 | 4 | GO:0004896 | |
| GeneOntologyMolecularFunction | azole transmembrane transporter activity | 3.32e-03 | 14 | 124 | 2 | GO:1901474 | |
| GeneOntologyMolecularFunction | nucleotide-sugar transmembrane transporter activity | 3.32e-03 | 14 | 124 | 2 | GO:0005338 | |
| GeneOntologyMolecularFunction | ABC-type transporter activity | 3.50e-03 | 49 | 124 | 3 | GO:0140359 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic anion channel activity | 3.70e-03 | 50 | 124 | 3 | GO:0099095 | |
| GeneOntologyMolecularFunction | voltage-gated potassium channel activity | 3.77e-03 | 102 | 124 | 4 | GO:0005249 | |
| GeneOntologyMolecularFunction | ABC-type xenobiotic transporter activity | 3.81e-03 | 15 | 124 | 2 | GO:0008559 | |
| GeneOntologyMolecularFunction | potassium ion transmembrane transporter activity | 3.90e-03 | 167 | 124 | 5 | GO:0015079 | |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 4.18e-03 | 105 | 124 | 4 | GO:0015171 | |
| GeneOntologyMolecularFunction | alanine transmembrane transporter activity | 4.34e-03 | 16 | 124 | 2 | GO:0022858 | |
| GeneOntologyMolecularFunction | oligopeptide transmembrane transporter activity | 4.34e-03 | 16 | 124 | 2 | GO:0035673 | |
| GeneOntologyMolecularFunction | sodium:chloride symporter activity | 4.89e-03 | 17 | 124 | 2 | GO:0015378 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic anion channel activity | 4.89e-03 | 17 | 124 | 2 | GO:0008308 | |
| GeneOntologyMolecularFunction | sodium-independent organic anion transmembrane transporter activity | 5.48e-03 | 18 | 124 | 2 | GO:0015347 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 5.63e-03 | 343 | 124 | 7 | GO:0005261 | |
| GeneOntologyMolecularFunction | monoatomic anion:sodium symporter activity | 6.10e-03 | 19 | 124 | 2 | GO:0015373 | |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | CACNA1D HCAR2 ABCA1 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 ADGRG1 ADGRL1 OR4D6 OR2S2 PTAFR LMBRD2 ACKR4 GRM8 CHRM2 OR10R2 ADCY2 OR2B11 HCAR3 TAS2R8 TAS2R13 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 ADGRF4 C5AR1 TAS2R31 TAS2R43 ADGRF1 GPR176 GPR45 OR2H2 SORL1 OR2A2 | 4.02e-18 | 1395 | 125 | 41 | GO:0007186 |
| GeneOntologyBiologicalProcess | sensory perception of chemical stimulus | TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 SLC6A3 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 C5AR1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 1.48e-11 | 547 | 125 | 21 | GO:0007606 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 1.08e-10 | 485 | 125 | 19 | GO:0050907 |
| GeneOntologyBiologicalProcess | sensory perception | CACNA1D RIPOR2 TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 CDH23 OR4D6 OR2S2 GRM8 OR10R2 SLC6A3 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 KCNQ3 OR1K1 C5AR1 TAS2R31 TAS2R43 SLC38A8 OR2H2 OR2A2 | 2.10e-10 | 1072 | 125 | 27 | GO:0007600 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 GRM8 OR10R2 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 3.36e-10 | 582 | 125 | 20 | GO:0050906 |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | ANO4 CACNA1D ANO2 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 ANO5 APOL1 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 CLCN7 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 3.51e-10 | 1017 | 125 | 26 | GO:0098660 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 3.99e-10 | 524 | 125 | 19 | GO:0009593 |
| GeneOntologyBiologicalProcess | monoatomic ion transport | ANO4 CACNA1D ANO2 ATP7A TRPA1 OSTM1 HCN4 HCN1 SLC38A5 CDH23 TCIRG1 ABCC5 ANO5 APOL1 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 CLCN7 P2RY4 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 5.34e-10 | 1374 | 125 | 30 | GO:0006811 |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | ANO4 CACNA1D ANO2 ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 ANO5 APOL1 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 CLCN7 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 2.46e-09 | 1115 | 125 | 26 | GO:0034220 |
| GeneOntologyBiologicalProcess | detection of stimulus | TRPA1 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 GRM8 OR10R2 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 1.33e-08 | 722 | 125 | 20 | GO:0051606 |
| GeneOntologyBiologicalProcess | monoatomic anion transport | ANO4 ANO2 TRPA1 OSTM1 ABCC5 ANO5 APOL1 CLCN3 CLCN7 P2RY4 ABCC2 | 1.53e-08 | 183 | 125 | 11 | GO:0006820 |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 SLC6A3 OR2B11 OR10AG1 OR10J5 OR52E5 OR1K1 OR2H2 OR2A2 | 1.48e-07 | 465 | 125 | 15 | GO:0007608 |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.57e-07 | 922 | 125 | 21 | GO:0098662 |
| GeneOntologyBiologicalProcess | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | CACNA1D ABCA1 MC2R ADGRG1 ADGRL1 GRM8 CHRM2 ADCY2 HRH4 ADGRF4 ADGRF1 GPR176 | 1.76e-07 | 286 | 125 | 12 | GO:0007188 |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 TCIRG1 ABCC5 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 2.24e-07 | 942 | 125 | 21 | GO:0098655 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 OR10AG1 OR10J5 OR52E5 OR1K1 OR2H2 OR2A2 | 3.75e-07 | 432 | 125 | 14 | GO:0050911 |
| GeneOntologyBiologicalProcess | neuron cellular homeostasis | 7.80e-07 | 84 | 125 | 7 | GO:0070050 | |
| GeneOntologyBiologicalProcess | chloride transport | 1.13e-06 | 128 | 125 | 8 | GO:0006821 | |
| GeneOntologyBiologicalProcess | monoatomic cation transport | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 CDH23 TCIRG1 ABCC5 SLC6A2 SLC38A1 SLC6A3 CLCN3 KCNT2 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.62e-06 | 1157 | 125 | 22 | GO:0006812 |
| GeneOntologyBiologicalProcess | metal ion transport | CACNA1D ATP7A TRPA1 HCN4 HCN1 SLC38A5 CDH23 ABCC5 SLC6A2 SLC38A1 SLC6A3 KCNT2 SLC24A2 NIPAL1 KCNQ3 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 2.41e-06 | 1000 | 125 | 20 | GO:0030001 |
| GeneOntologyBiologicalProcess | monoatomic anion transmembrane transport | 4.31e-06 | 153 | 125 | 8 | GO:0098656 | |
| GeneOntologyBiologicalProcess | inorganic anion transport | 1.42e-05 | 180 | 125 | 8 | GO:0015698 | |
| GeneOntologyBiologicalProcess | export across plasma membrane | 1.92e-05 | 91 | 125 | 6 | GO:0140115 | |
| GeneOntologyBiologicalProcess | export from cell | CACNA1D TRAPPC11 HCAR2 ABCA1 TRPA1 SLC38A5 TCIRG1 ABCC5 PTAFR GRM8 HCAR3 FCER1A KCNT2 P2RY4 LRP5 KCNQ3 ABCC2 ATP2A2 ATP2B3 CKLF | 1.98e-05 | 1153 | 125 | 20 | GO:0140352 |
| GeneOntologyBiologicalProcess | import into cell | NPC1 CACNA1D ABCA1 HCN4 ICAM3 SLC38A5 AP3M1 SLITRK1 SLC6A2 SLC38A1 SLC6A3 CLCN3 SLC24A2 ACKR3 SLC28A1 AP3M2 LRP5 KCNQ3 SORL1 | 2.50e-05 | 1074 | 125 | 19 | GO:0098657 |
| GeneOntologyBiologicalProcess | transepithelial chloride transport | 2.53e-05 | 10 | 125 | 3 | GO:0030321 | |
| GeneOntologyBiologicalProcess | circulatory system process | CACNA1D TRPA1 HCN4 SLC38A5 ABCC5 PTAFR PPCS CHRM2 SLC38A1 TBC1D8 LRP5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 3.81e-05 | 733 | 125 | 15 | GO:0003013 |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 4.01e-05 | 208 | 125 | 8 | GO:0035725 | |
| GeneOntologyBiologicalProcess | chloride transmembrane transport | 6.22e-05 | 112 | 125 | 6 | GO:1902476 | |
| GeneOntologyBiologicalProcess | transepithelial transport | 8.09e-05 | 38 | 125 | 4 | GO:0070633 | |
| GeneOntologyBiologicalProcess | positive regulation of endoplasmic reticulum calcium ion concentration | 1.09e-04 | 3 | 125 | 2 | GO:0032470 | |
| GeneOntologyBiologicalProcess | regulation of action potential | 1.34e-04 | 81 | 125 | 5 | GO:0098900 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of bitter taste | 1.45e-04 | 44 | 125 | 4 | GO:0001580 | |
| GeneOntologyBiologicalProcess | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 1.66e-04 | 191 | 125 | 7 | GO:0007189 | |
| GeneOntologyBiologicalProcess | inorganic anion transmembrane transport | 1.67e-04 | 134 | 125 | 6 | GO:0098661 | |
| GeneOntologyBiologicalProcess | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 1.77e-04 | 86 | 125 | 5 | GO:0007193 | |
| GeneOntologyBiologicalProcess | amino acid transport | 1.89e-04 | 195 | 125 | 7 | GO:0006865 | |
| GeneOntologyBiologicalProcess | sensory perception of bitter taste | 2.03e-04 | 48 | 125 | 4 | GO:0050913 | |
| GeneOntologyBiologicalProcess | positive regulation of adiponectin secretion | 2.17e-04 | 4 | 125 | 2 | GO:0070165 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of taste | 2.39e-04 | 50 | 125 | 4 | GO:0050912 | |
| GeneOntologyBiologicalProcess | sodium ion transport | 2.76e-04 | 275 | 125 | 8 | GO:0006814 | |
| GeneOntologyBiologicalProcess | cardiac conduction | 3.59e-04 | 100 | 125 | 5 | GO:0061337 | |
| GeneOntologyBiologicalProcess | L-glutamine import across plasma membrane | 3.60e-04 | 5 | 125 | 2 | GO:1903803 | |
| GeneOntologyBiologicalProcess | membrane depolarization during SA node cell action potential | 3.60e-04 | 5 | 125 | 2 | GO:0086046 | |
| GeneOntologyBiologicalProcess | secretion | CACNA1D TRAPPC11 HCAR2 ABCA1 ATP7A TRPA1 TCIRG1 PTAFR GRM8 SLC6A3 HCAR3 FCER1A P2RY4 LRP5 KCNQ3 ABCC2 ATP2A2 CKLF | 4.06e-04 | 1221 | 125 | 18 | GO:0046903 |
| GeneOntologyBiologicalProcess | carboxylic acid transmembrane transport | 4.80e-04 | 163 | 125 | 6 | GO:1905039 | |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 5.14e-04 | 61 | 125 | 4 | GO:0007187 | |
| GeneOntologyBiologicalProcess | organic acid transmembrane transport | 5.46e-04 | 167 | 125 | 6 | GO:1903825 | |
| GeneOntologyBiologicalProcess | regulation of cardiac conduction | 7.08e-04 | 29 | 125 | 3 | GO:1903779 | |
| GeneOntologyBiologicalProcess | clathrin-coated vesicle cargo loading | 7.50e-04 | 7 | 125 | 2 | GO:0035652 | |
| GeneOntologyBiologicalProcess | clathrin-coated vesicle cargo loading, AP-3-mediated | 7.50e-04 | 7 | 125 | 2 | GO:0035654 | |
| GeneOntologyBiologicalProcess | calcium ion import into sarcoplasmic reticulum | 7.50e-04 | 7 | 125 | 2 | GO:1990036 | |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | CACNA1D ATP7A TRPA1 CDH23 TCIRG1 GCKR CLCN3 P2RY4 SLC24A2 LRP5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 7.74e-04 | 866 | 125 | 14 | GO:0055082 |
| GeneOntologyBiologicalProcess | sensory perception of taste | 8.65e-04 | 70 | 125 | 4 | GO:0050909 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | CACNA1D ATP7A TRPA1 CDH23 TCIRG1 GCKR SLC6A2 CLCN3 P2RY4 SLC24A2 LRP5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 8.83e-04 | 981 | 125 | 15 | GO:0019725 |
| GeneOntologyBiologicalProcess | carboxylic acid transport | SLC38A5 ABCC5 SLC7A6 SLCO1B7 SLC38A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 8.92e-04 | 410 | 125 | 9 | GO:0046942 |
| GeneOntologyBiologicalProcess | organic acid transport | SLC38A5 ABCC5 SLC7A6 SLCO1B7 SLC38A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 9.23e-04 | 412 | 125 | 9 | GO:0015849 |
| GeneOntologyBiologicalProcess | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway | 9.96e-04 | 8 | 125 | 2 | GO:0007197 | |
| GeneOntologyBiologicalProcess | adiponectin secretion | 9.96e-04 | 8 | 125 | 2 | GO:0070162 | |
| GeneOntologyBiologicalProcess | regulation of adiponectin secretion | 9.96e-04 | 8 | 125 | 2 | GO:0070163 | |
| GeneOntologyBiologicalProcess | regulation of cardiac muscle cell action potential involved in regulation of contraction | 9.96e-04 | 8 | 125 | 2 | GO:0098909 | |
| GeneOntologyBiologicalProcess | negative regulation of lipid catabolic process | 1.13e-03 | 34 | 125 | 3 | GO:0050995 | |
| GeneOntologyBiologicalProcess | organic anion transport | SLC38A5 ABCC5 SLC7A6 SLCO1B7 SLC38A1 SLCO5A1 SLC16A14 SLC13A5 ABCC2 SLC38A8 | 1.18e-03 | 515 | 125 | 10 | GO:0015711 |
| GeneOntologyBiologicalProcess | norepinephrine uptake | 1.28e-03 | 9 | 125 | 2 | GO:0051620 | |
| GeneOntologyCellularComponent | basolateral plasma membrane | ABCA1 ATP7A HCN4 HCN1 ABCC5 SLCO1B7 SLC38A1 SLCO5A1 P2RY4 SLC13A5 C5AR1 | 3.58e-06 | 320 | 125 | 11 | GO:0016323 |
| GeneOntologyCellularComponent | presynaptic membrane | CACNA1D ANO2 HCN1 ADGRL1 GRM8 CHRM2 SLC6A2 SLC6A3 P2RY4 ATP2B3 | 6.60e-06 | 277 | 125 | 10 | GO:0042734 |
| GeneOntologyCellularComponent | basal plasma membrane | ABCA1 ATP7A HCN4 HCN1 ABCC5 SLCO1B7 SLC38A1 SLCO5A1 P2RY4 SLC13A5 C5AR1 | 9.33e-06 | 354 | 125 | 11 | GO:0009925 |
| GeneOntologyCellularComponent | basal part of cell | ABCA1 ATP7A HCN4 HCN1 ABCC5 SLCO1B7 SLC38A1 SLCO5A1 P2RY4 SLC13A5 C5AR1 | 1.72e-05 | 378 | 125 | 11 | GO:0045178 |
| GeneOntologyCellularComponent | axon | ATP7A TRPA1 HCN4 HCN1 CYP17A1 ADGRL1 CHRM2 AP3M1 SLC6A2 SLC38A1 SLC6A3 CLCN3 AP3M2 KCNQ3 SEMA6A ATP2B3 SLC38A8 | 2.30e-05 | 891 | 125 | 17 | GO:0030424 |
| GeneOntologyCellularComponent | apical part of cell | CACNA1D RIPOR2 ATP7A TRPA1 CDH23 TCIRG1 ABCC5 SLC38A1 CLCN3 P2RY4 SLC28A1 C5AR1 ABCC2 | 5.57e-05 | 592 | 125 | 13 | GO:0045177 |
| GeneOntologyCellularComponent | apical plasma membrane | CACNA1D RIPOR2 ATP7A TRPA1 TCIRG1 ABCC5 SLC38A1 CLCN3 P2RY4 SLC28A1 ABCC2 | 1.67e-04 | 487 | 125 | 11 | GO:0016324 |
| GeneOntologyCellularComponent | synaptic membrane | CACNA1D ANO2 HCN1 ADGRL1 GRM8 CHRM2 SLITRK1 SLC6A2 SLC6A3 CLCN3 P2RY4 ATP2B3 | 1.99e-04 | 583 | 125 | 12 | GO:0097060 |
| GeneOntologyCellularComponent | HCN channel complex | 2.11e-04 | 4 | 125 | 2 | GO:0098855 | |
| GeneOntologyCellularComponent | cluster of actin-based cell projections | 3.93e-04 | 223 | 125 | 7 | GO:0098862 | |
| GeneOntologyCellularComponent | cochlear hair cell ribbon synapse | 5.24e-04 | 6 | 125 | 2 | GO:0098683 | |
| GeneOntologyCellularComponent | presynapse | CACNA1D ANO2 HCN4 HCN1 ADGRL1 GRM8 CHRM2 SLC6A2 SLC6A3 CLCN3 P2RY4 SLC24A2 AP3M2 ATP2B3 | 8.49e-04 | 886 | 125 | 14 | GO:0098793 |
| GeneOntologyCellularComponent | ribbon synapse | 9.12e-04 | 32 | 125 | 3 | GO:0097470 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | CACNA1D ANO2 OSTM1 HCN4 HCN1 TCIRG1 CLCN7 KCNQ3 ATP2A1 ATP2A2 | 1.20e-03 | 523 | 125 | 10 | GO:1902495 |
| GeneOntologyCellularComponent | presynaptic active zone membrane | 1.24e-03 | 78 | 125 | 4 | GO:0048787 | |
| GeneOntologyCellularComponent | platelet dense tubular network membrane | 1.24e-03 | 9 | 125 | 2 | GO:0031095 | |
| GeneOntologyCellularComponent | stereocilium bundle | 1.30e-03 | 79 | 125 | 4 | GO:0032421 | |
| GeneOntologyCellularComponent | transporter complex | CACNA1D ANO2 OSTM1 HCN4 HCN1 TCIRG1 CLCN7 KCNQ3 ATP2A1 ATP2A2 | 1.74e-03 | 550 | 125 | 10 | GO:1990351 |
| GeneOntologyCellularComponent | platelet dense tubular network | 1.88e-03 | 11 | 125 | 2 | GO:0031094 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 1.99e-03 | 378 | 125 | 8 | GO:0034702 | |
| GeneOntologyCellularComponent | AP-3 adaptor complex | 2.65e-03 | 13 | 125 | 2 | GO:0030123 | |
| GeneOntologyCellularComponent | GABA-ergic synapse | 3.08e-03 | 164 | 125 | 5 | GO:0098982 | |
| GeneOntologyCellularComponent | endosome | NPC1 ABCA1 ATP7A TCIRG1 ABCC5 ACKR4 AP3M1 TMBIM1 SPPL2A CLCN3 ACKR3 AP3M2 KIR3DL3 DYNC1LI2 SORL1 | 4.16e-03 | 1167 | 125 | 15 | GO:0005768 |
| GeneOntologyCellularComponent | neuronal cell body | CACNA1D ATP7A HCN4 HCN1 CYP17A1 GRM8 CHRM2 SLC6A2 SLC38A1 SLC6A3 KCNQ3 SORL1 | 4.33e-03 | 835 | 125 | 12 | GO:0043025 |
| GeneOntologyCellularComponent | cell projection membrane | 4.42e-03 | 431 | 125 | 8 | GO:0031253 | |
| HumanPheno | Osteopetrosis | 1.42e-05 | 19 | 42 | 4 | HP:0011002 | |
| Domain | G_PROTEIN_RECEP_F1_2 | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 OR4D6 OR2S2 PTAFR ACKR4 CHRM2 OR10R2 OR2B11 HCAR3 TAS2R8 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 C5AR1 GPR176 GPR45 OR2H2 OR2A2 | 6.63e-15 | 691 | 123 | 28 | PS50262 |
| Domain | GPCR_Rhodpsn | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 OR4D6 OR2S2 PTAFR ACKR4 CHRM2 OR10R2 OR2B11 HCAR3 TAS2R8 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 C5AR1 GPR176 GPR45 OR2H2 OR2A2 | 6.87e-15 | 692 | 123 | 28 | IPR000276 |
| Domain | GPCR_Rhodpsn_7TM | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 OR4D6 OR2S2 PTAFR ACKR4 CHRM2 OR10R2 OR2B11 HCAR3 TAS2R8 OR10AG1 OR10J5 P2RY4 ACKR3 HRH4 OR1K1 C5AR1 GPR176 GPR45 OR2H2 OR2A2 | 2.50e-14 | 670 | 123 | 27 | IPR017452 |
| Domain | 7tm_1 | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 OR4D6 OR2S2 PTAFR ACKR4 CHRM2 OR10R2 OR2B11 HCAR3 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 C5AR1 GPR176 GPR45 OR2H2 OR2A2 | 3.21e-14 | 677 | 123 | 27 | PF00001 |
| Domain | G_PROTEIN_RECEP_F1_1 | HCAR2 MRGPRD OR2G6 OR2G3 MC2R OR2G2 OR5K4 OR4D6 OR2S2 PTAFR ACKR4 CHRM2 OR10R2 OR2B11 HCAR3 OR10AG1 OR10J5 P2RY4 ACKR3 OR52E5 HRH4 OR1K1 C5AR1 GPR176 GPR45 OR2H2 OR2A2 | 4.25e-14 | 685 | 123 | 27 | PS00237 |
| Domain | Olfact_rcpt | OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 OR10AG1 OR10J5 OR52E5 OR1K1 OR2H2 OR2A2 | 3.19e-07 | 393 | 123 | 14 | IPR000725 |
| Domain | Anoct_dimer | 9.57e-06 | 7 | 123 | 3 | PF16178 | |
| Domain | Anoct_dimer | 9.57e-06 | 7 | 123 | 3 | IPR032394 | |
| Domain | TAS2R | 2.39e-05 | 26 | 123 | 4 | PF05296 | |
| Domain | T2R | 2.39e-05 | 26 | 123 | 4 | IPR007960 | |
| Domain | Hydrolase_3 | 3.23e-05 | 10 | 123 | 3 | PF08282 | |
| Domain | Anoctamin | 3.23e-05 | 10 | 123 | 3 | PF04547 | |
| Domain | Anoctamin | 3.23e-05 | 10 | 123 | 3 | IPR007632 | |
| Domain | HCAR2/3_rcpt | 4.30e-05 | 2 | 123 | 2 | IPR028017 | |
| Domain | GPS | 8.01e-05 | 35 | 123 | 4 | PF01825 | |
| Domain | ATPase_P-typ_cyto_domN | 8.01e-05 | 35 | 123 | 4 | IPR023299 | |
| Domain | P_typ_ATPase | 8.96e-05 | 36 | 123 | 4 | IPR001757 | |
| Domain | ATPase_P-typ_P_site | 8.96e-05 | 36 | 123 | 4 | IPR018303 | |
| Domain | GPS | 8.96e-05 | 36 | 123 | 4 | PS50221 | |
| Domain | ATPASE_E1_E2 | 8.96e-05 | 36 | 123 | 4 | PS00154 | |
| Domain | GPS | 1.00e-04 | 37 | 123 | 4 | IPR000203 | |
| Domain | ATPase_P-typ_transduc_dom_A | 1.00e-04 | 37 | 123 | 4 | IPR008250 | |
| Domain | E1-E2_ATPase | 1.00e-04 | 37 | 123 | 4 | PF00122 | |
| Domain | P-type_ATPase_IIA | 1.29e-04 | 3 | 123 | 2 | IPR005782 | |
| Domain | - | 1.47e-04 | 16 | 123 | 3 | 1.20.1110.10 | |
| Domain | ATPase_P-typ_TM_dom | 1.47e-04 | 16 | 123 | 3 | IPR023298 | |
| Domain | ATPase_P-typ_cation-transptr_C | 1.77e-04 | 17 | 123 | 3 | IPR006068 | |
| Domain | Cation_ATPase_C | 1.77e-04 | 17 | 123 | 3 | PF00689 | |
| Domain | Aa_trans | 1.77e-04 | 17 | 123 | 3 | PF01490 | |
| Domain | AA_transpt_TM | 1.77e-04 | 17 | 123 | 3 | IPR013057 | |
| Domain | Cation_ATPase_N | 2.12e-04 | 18 | 123 | 3 | PF00690 | |
| Domain | Cation_ATPase_N | 2.12e-04 | 18 | 123 | 3 | SM00831 | |
| Domain | ATPase_P-typ_cation-transptr_N | 2.50e-04 | 19 | 123 | 3 | IPR004014 | |
| Domain | GPCR_2_Ig-hepta-like_rcpt | 2.56e-04 | 4 | 123 | 2 | IPR008078 | |
| Domain | Ion_trans_N | 2.56e-04 | 4 | 123 | 2 | PF08412 | |
| Domain | Ion_trans_N | 2.56e-04 | 4 | 123 | 2 | IPR013621 | |
| Domain | G_PROTEIN_RECEP_F2_2 | 3.26e-04 | 50 | 123 | 4 | PS00650 | |
| Domain | 7tm_2 | 3.26e-04 | 50 | 123 | 4 | PF00002 | |
| Domain | Clathrin_mu_CS | 6.34e-04 | 6 | 123 | 2 | IPR018240 | |
| Domain | CLAT_ADAPTOR_M_1 | 6.34e-04 | 6 | 123 | 2 | PS00990 | |
| Domain | CLAT_ADAPTOR_M_2 | 6.34e-04 | 6 | 123 | 2 | PS00991 | |
| Domain | GPCR_2_secretin-like | 6.57e-04 | 60 | 123 | 4 | IPR000832 | |
| Domain | GPCR_2-like | 6.57e-04 | 60 | 123 | 4 | IPR017981 | |
| Domain | G_PROTEIN_RECEP_F2_4 | 6.99e-04 | 61 | 123 | 4 | PS50261 | |
| Domain | Ion_trans_dom | 9.46e-04 | 114 | 123 | 5 | IPR005821 | |
| Domain | Ion_trans | 9.46e-04 | 114 | 123 | 5 | PF00520 | |
| Domain | - | 1.20e-03 | 32 | 123 | 3 | 3.40.1110.10 | |
| Domain | - | 1.20e-03 | 32 | 123 | 3 | 2.70.150.10 | |
| Domain | GPS | 1.44e-03 | 34 | 123 | 3 | SM00303 | |
| Domain | Cl-channel_core | 1.50e-03 | 9 | 123 | 2 | IPR014743 | |
| Domain | - | 1.50e-03 | 9 | 123 | 2 | 1.10.3080.10 | |
| Domain | Voltage_CLC | 1.50e-03 | 9 | 123 | 2 | PF00654 | |
| Domain | Cl-channel_volt-gated | 1.50e-03 | 9 | 123 | 2 | IPR001807 | |
| Domain | HAD-like_dom | 1.84e-03 | 79 | 123 | 4 | IPR023214 | |
| Domain | Clathrin_mu | 1.87e-03 | 10 | 123 | 2 | IPR001392 | |
| Domain | Adap_comp_sub | 2.28e-03 | 11 | 123 | 2 | PF00928 | |
| Domain | G_PROTEIN_RECEP_F2_1 | 2.31e-03 | 40 | 123 | 3 | PS00649 | |
| Domain | GPCR_2_extracellular_dom | 2.31e-03 | 40 | 123 | 3 | IPR001879 | |
| Domain | G_PROTEIN_RECEP_F2_3 | 2.31e-03 | 40 | 123 | 3 | PS50227 | |
| Domain | ABC_transporter_CS | 2.65e-03 | 42 | 123 | 3 | IPR017871 | |
| Domain | Clathrin_sm-chain_CS | 2.72e-03 | 12 | 123 | 2 | IPR000804 | |
| Domain | OA_transporter | 2.72e-03 | 12 | 123 | 2 | IPR004156 | |
| Domain | OATP | 2.72e-03 | 12 | 123 | 2 | PF03137 | |
| Domain | MHD | 3.20e-03 | 13 | 123 | 2 | PS51072 | |
| Domain | MHD | 3.20e-03 | 13 | 123 | 2 | IPR028565 | |
| Domain | K_chnl_volt-dep_EAG/ELK/ERG | 3.72e-03 | 14 | 123 | 2 | IPR003938 | |
| Domain | Ldl_recept_b | 3.72e-03 | 14 | 123 | 2 | PF00058 | |
| Domain | LDLRB | 3.72e-03 | 14 | 123 | 2 | PS51120 | |
| Domain | ABC_tran | 3.88e-03 | 48 | 123 | 3 | PF00005 | |
| Domain | ABC_TRANSPORTER_2 | 3.88e-03 | 48 | 123 | 3 | PS50893 | |
| Domain | ABC_TRANSPORTER_1 | 4.12e-03 | 49 | 123 | 3 | PS00211 | |
| Domain | LY | 4.27e-03 | 15 | 123 | 2 | SM00135 | |
| Domain | LDLR_classB_rpt | 4.27e-03 | 15 | 123 | 2 | IPR000033 | |
| Domain | ABC_transporter-like | 4.36e-03 | 50 | 123 | 3 | IPR003439 | |
| Domain | CBS | 4.86e-03 | 16 | 123 | 2 | SM00116 | |
| Domain | AP_mu_sigma_su | 4.86e-03 | 16 | 123 | 2 | IPR022775 | |
| Domain | cNMP-bd_CS | 4.86e-03 | 16 | 123 | 2 | IPR018488 | |
| Domain | Clat_adaptor_s | 4.86e-03 | 16 | 123 | 2 | PF01217 | |
| Domain | - | 6.14e-03 | 18 | 123 | 2 | 1.20.144.10 | |
| Domain | NA_NEUROTRAN_SYMP_2 | 6.14e-03 | 18 | 123 | 2 | PS00754 | |
| Domain | acidPPc | 6.14e-03 | 18 | 123 | 2 | SM00014 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | NPC1 ANO4 ANO2 ABCA1 ATP7A TRPA1 OSTM1 SLC38A5 TCIRG1 ABCC5 ANO5 SLC7A6 ADCY2 SLC6A2 SLC38A1 SLC6A3 LMF2 CLCN3 MBTPS2 CLCN7 SLC24A2 SLC28A1 NIPAL1 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 2.38e-13 | 736 | 103 | 28 | M27287 |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | NPC1 ANO4 ANO2 ABCA1 ATP7A TRPA1 OSTM1 SLC38A5 TCIRG1 ABCC5 ANO5 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 LMF2 CLCN7 SLC24A2 SLC28A1 NIPAL1 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.90e-12 | 681 | 103 | 26 | MM14985 |
| Pathway | REACTOME_SENSORY_PERCEPTION | MPP1 CACNA1D ANO2 RIPOR2 OR2G6 OR2G3 OR2G2 OR5K4 CDH23 OR4D6 OR2S2 OR10R2 OR2B11 TAS2R8 TAS2R13 OR10AG1 OR10J5 OR52E5 OR1K1 TAS2R31 TAS2R43 OR2H2 OR2A2 | 1.35e-10 | 636 | 103 | 23 | M41834 |
| Pathway | WP_GPCRS_NONODORANT | HCAR2 MRGPRD MC2R ADGRG1 ADGRL1 PTAFR GRM8 CHRM2 HCAR3 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 | 7.93e-09 | 266 | 103 | 14 | MM15843 |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | ANO4 ANO2 ATP7A TRPA1 OSTM1 TCIRG1 ANO5 CLCN3 CLCN7 ATP2A1 ATP2A2 ATP2B3 | 8.73e-09 | 183 | 103 | 12 | M997 |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | ANO4 ANO2 ATP7A TRPA1 OSTM1 TCIRG1 ANO5 CLCN7 ATP2A1 ATP2A2 ATP2B3 | 6.20e-08 | 176 | 103 | 11 | MM15718 |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | HCAR2 MC2R PTAFR ACKR4 GRM8 CHRM2 HCAR3 TAS2R8 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 PLPPR2 | 2.30e-07 | 463 | 103 | 16 | M507 |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | ANO2 OR2G6 OR2G3 OR2G2 OR5K4 OR4D6 OR2S2 OR10R2 OR2B11 OR10AG1 OR10J5 OR52E5 OR1K1 OR2H2 OR2A2 | 3.42e-07 | 417 | 103 | 15 | M4072 |
| Pathway | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | HCAR2 GRM8 CHRM2 ADCY2 HCAR3 TAS2R8 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 | 4.59e-07 | 314 | 103 | 13 | M600 |
| Pathway | REACTOME_GPCR_LIGAND_BINDING | HCAR2 MC2R PTAFR ACKR4 GRM8 CHRM2 HCAR3 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 PLPPR2 | 5.06e-07 | 430 | 103 | 15 | MM15160 |
| Pathway | REACTOME_SIGNALING_BY_GPCR | HCAR2 MC2R PTAFR ACKR4 GRM8 CHRM2 ADCY2 HCAR3 TAS2R8 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 PLPPR2 GPR176 GPR45 | 6.60e-07 | 702 | 103 | 19 | M746 |
| Pathway | REACTOME_SIGNALING_BY_GPCR | HCAR2 MC2R PTAFR ACKR4 GRM8 CHRM2 ADCY2 HCAR3 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 PLPPR2 GPR176 GPR45 | 8.94e-07 | 646 | 103 | 18 | MM14962 |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 1.02e-06 | 186 | 103 | 10 | MM15994 | |
| Pathway | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | HCAR2 GRM8 CHRM2 ADCY2 HCAR3 TAS2R13 P2RY4 ACKR3 HRH4 C5AR1 TAS2R31 TAS2R43 | 1.27e-06 | 289 | 103 | 12 | MM15057 |
| Pathway | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | 8.93e-06 | 39 | 103 | 5 | M793 | |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 1.22e-05 | 106 | 103 | 7 | M27200 | |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 2.00e-05 | 260 | 103 | 10 | M39397 | |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | OR2G6 OR2G3 OR2G2 OR4D6 OR2S2 OR10R2 OR2B11 OR10AG1 OR10J5 OR1K1 OR2H2 OR2A2 | 2.62e-05 | 389 | 103 | 12 | M14091 |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | HCAR2 MC2R PTAFR ACKR4 CHRM2 HCAR3 P2RY4 ACKR3 HRH4 C5AR1 PLPPR2 | 2.87e-05 | 330 | 103 | 11 | M18334 |
| Pathway | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | HCAR2 MC2R PTAFR ACKR4 CHRM2 HCAR3 P2RY4 ACKR3 HRH4 C5AR1 PLPPR2 | 3.11e-05 | 333 | 103 | 11 | MM14963 |
| Pathway | WP_AUTOSOMAL_RECESSIVE_OSTEOPETROSIS_PATHWAYS | 5.99e-05 | 11 | 103 | 3 | M39871 | |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC38A5 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLC24A2 SLC28A1 SLC13A5 | 6.06e-05 | 238 | 103 | 9 | MM15076 |
| Pathway | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | 7.94e-05 | 12 | 103 | 3 | M27326 | |
| Pathway | REACTOME_STIMULI_SENSING_CHANNELS | 8.50e-05 | 99 | 103 | 6 | MM14910 | |
| Pathway | REACTOME_INDUCTION_OF_CELL_CELL_FUSION | 1.03e-04 | 13 | 103 | 3 | M46426 | |
| Pathway | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | 1.30e-04 | 14 | 103 | 3 | MM15052 | |
| Pathway | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | 1.47e-04 | 37 | 103 | 4 | MM15067 | |
| Pathway | KEGG_CALCIUM_SIGNALING_PATHWAY | 3.25e-04 | 178 | 103 | 7 | M2890 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 3.77e-04 | 47 | 103 | 4 | M42524 | |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC38A5 SLC7A6 SLC6A2 SLC38A1 SLC6A3 SLC24A2 SLC28A1 SLC13A5 | 4.75e-04 | 249 | 103 | 8 | M5988 |
| Pathway | KEGG_MEDICUS_PATHOGEN_SALMONELLA_SPVD_TO_TNF_NFKB_SIGNALING_PATHWAY | 5.21e-04 | 5 | 103 | 2 | M48980 | |
| Pathway | KEGG_TASTE_TRANSDUCTION | 5.56e-04 | 52 | 103 | 4 | M5785 | |
| Pathway | WP_GPCRS_OTHER | 5.90e-04 | 93 | 103 | 5 | M39629 | |
| Pathway | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 6.89e-04 | 55 | 103 | 4 | M971 | |
| Pathway | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 7.89e-04 | 57 | 103 | 4 | MM15643 | |
| Pathway | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | 9.75e-04 | 27 | 103 | 3 | MM15053 | |
| Pathway | WP_GPCRS_ODORANT | 1.02e-03 | 157 | 103 | 6 | MM15872 | |
| Pathway | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | 1.09e-03 | 28 | 103 | 3 | M924 | |
| Pathway | KEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA | 1.44e-03 | 8 | 103 | 2 | M47955 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 1.47e-03 | 31 | 103 | 3 | MM15691 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 1.61e-03 | 32 | 103 | 3 | MM14957 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 1.76e-03 | 33 | 103 | 3 | M188 | |
| Pathway | WP_ACETAMINOPHEN_IN_ANALGESIA_AND_ANTIPYRESIS | 1.84e-03 | 9 | 103 | 2 | M48307 | |
| Pathway | REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE | 2.20e-03 | 75 | 103 | 4 | M27032 | |
| Pathway | REACTOME_SENSORY_PROCESSING_OF_SOUND | 2.42e-03 | 77 | 103 | 4 | M41822 | |
| Pubmed | Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration. | 4.76e-08 | 3 | 127 | 3 | 15706348 | |
| Pubmed | A single-center experience in 20 patients with infantile malignant osteopetrosis. | 1.90e-07 | 4 | 127 | 3 | 19507210 | |
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | 8.39e-07 | 139 | 127 | 7 | 16985003 | |
| Pubmed | Identification and characterization of TMEM16E and TMEM16F genes in silico. | 9.43e-07 | 6 | 127 | 3 | 15067359 | |
| Pubmed | 9.43e-07 | 6 | 127 | 3 | 29937375 | ||
| Pubmed | 9.67e-07 | 21 | 127 | 4 | 10761934 | ||
| Pubmed | The molecular receptive ranges of human TAS2R bitter taste receptors. | 1.42e-06 | 23 | 127 | 4 | 20022913 | |
| Pubmed | ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins. | 1.65e-06 | 7 | 127 | 3 | 22075693 | |
| Pubmed | Systematic protein-protein interaction mapping for clinically relevant human GPCRs. | NPC1 TMEM144 MC2R ADGRG1 PTAFR CHRM2 ADCY2 TMBIM1 TMCC2 IL17RD ATP2A1 ATP2A2 ATP2B3 | 1.77e-06 | 697 | 127 | 13 | 28298427 |
| Pubmed | 2.02e-06 | 25 | 127 | 4 | 12139982 | ||
| Pubmed | Molecular mechanisms of bitter and sweet taste transduction. | 2.38e-06 | 26 | 127 | 4 | 11696554 | |
| Pubmed | 2.63e-06 | 8 | 127 | 3 | 10951186 | ||
| Pubmed | 2.79e-06 | 27 | 127 | 4 | 12581520 | ||
| Pubmed | 3.75e-06 | 29 | 127 | 4 | 15071553 | ||
| Pubmed | Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. | 5.60e-06 | 10 | 127 | 3 | 23532839 | |
| Pubmed | Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels. | 5.60e-06 | 10 | 127 | 3 | 19015192 | |
| Pubmed | 5.60e-06 | 10 | 127 | 3 | 24692353 | ||
| Pubmed | International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. | 6.39e-06 | 33 | 127 | 4 | 25713288 | |
| Pubmed | 7.22e-06 | 34 | 127 | 4 | 15496549 | ||
| Pubmed | 7.25e-06 | 126 | 127 | 6 | 17897319 | ||
| Pubmed | Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development. | 1.14e-05 | 38 | 127 | 4 | 30786075 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 24108692 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 28186140 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 12556521 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30154797 | ||
| Pubmed | The role of HCA2 (GPR109A) in regulating macrophage function. | 1.32e-05 | 2 | 127 | 2 | 23882124 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 36891315 | ||
| Pubmed | Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a. | 1.32e-05 | 2 | 127 | 2 | 38007572 | |
| Pubmed | ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity. | 1.32e-05 | 2 | 127 | 2 | 21527911 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 32851177 | ||
| Pubmed | Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE. | 1.32e-05 | 2 | 127 | 2 | 24691444 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 31347703 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 19644701 | ||
| Pubmed | Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis. | 1.32e-05 | 2 | 127 | 2 | 30659164 | |
| Pubmed | Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels. | 1.32e-05 | 2 | 127 | 2 | 17548059 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 19223991 | ||
| Pubmed | Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. | 1.32e-05 | 2 | 127 | 2 | 24820037 | |
| Pubmed | Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice. | 1.32e-05 | 2 | 127 | 2 | 23967184 | |
| Pubmed | Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles. | 1.32e-05 | 2 | 127 | 2 | 14638697 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 26371038 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 34653248 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 19136666 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 33488584 | ||
| Pubmed | Lactate-induced activation of HCA2 improves survival in mice with sepsis. | 1.32e-05 | 2 | 127 | 2 | 30951370 | |
| Pubmed | ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. | 1.32e-05 | 2 | 127 | 2 | 16525474 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 15537898 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 31858105 | ||
| Pubmed | Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy. | 1.32e-05 | 2 | 127 | 2 | 32068460 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30657794 | ||
| Pubmed | Localization of the gene causing autosomal dominant osteopetrosis type I to chromosome 11q12-13. | 1.32e-05 | 2 | 127 | 2 | 12054167 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 34092246 | ||
| Pubmed | Molecular identification of high and low affinity receptors for nicotinic acid. | 1.32e-05 | 2 | 127 | 2 | 12522134 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30271409 | ||
| Pubmed | Niacin fine-tunes energy homeostasis through canonical GPR109A signaling. | 1.32e-05 | 2 | 127 | 2 | 30596513 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 35320002 | ||
| Pubmed | GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. | 1.32e-05 | 2 | 127 | 2 | 16322797 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 18983141 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 31366236 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 11093780 | ||
| Pubmed | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. | 1.32e-05 | 2 | 127 | 2 | 32749217 | |
| Pubmed | GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice. | 1.32e-05 | 2 | 127 | 2 | 35489706 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 15718407 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 22712725 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 19561068 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 11402072 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 33104153 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 17702579 | ||
| Pubmed | The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. | 1.32e-05 | 2 | 127 | 2 | 24371223 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 26786096 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 21774590 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 14584882 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 20700532 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 36208084 | ||
| Pubmed | A role for cortical dopamine in the paradoxical calming effects of psychostimulants. | 1.32e-05 | 2 | 127 | 2 | 35210489 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 26656756 | ||
| Pubmed | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation. | 1.32e-05 | 2 | 127 | 2 | 37597514 | |
| Pubmed | The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism. | 1.32e-05 | 2 | 127 | 2 | 33924461 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 33977048 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 11745392 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30148678 | ||
| Pubmed | Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets. | 1.32e-05 | 2 | 127 | 2 | 25622782 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 21456027 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 33420329 | ||
| Pubmed | Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli. | 1.32e-05 | 2 | 127 | 2 | 11675786 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 12646212 | ||
| Pubmed | PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. | 1.32e-05 | 2 | 127 | 2 | 12563315 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 11784783 | ||
| Pubmed | Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology. | 1.32e-05 | 2 | 127 | 2 | 10603953 | |
| Pubmed | Formalin evokes calcium transients from the endoplasmatic reticulum. | 1.32e-05 | 2 | 127 | 2 | 25875358 | |
| Pubmed | Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight. | 1.32e-05 | 2 | 127 | 2 | 34769190 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 15763138 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30625381 | ||
| Pubmed | Novel mutations in Indian patients with autosomal recessive infantile malignant osteopetrosis. | 1.32e-05 | 2 | 127 | 2 | 20424301 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 30085883 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 21655214 | ||
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 18953100 | ||
| Pubmed | (D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. | 1.32e-05 | 2 | 127 | 2 | 15929991 | |
| Pubmed | 1.32e-05 | 2 | 127 | 2 | 36991440 | ||
| Pubmed | Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages. | 1.32e-05 | 2 | 127 | 2 | 25320346 | |
| Pubmed | CLCN7 and TCIRG1 mutations in a single family: Evidence for digenic inheritance of osteopetrosis. | 1.32e-05 | 2 | 127 | 2 | 30431110 | |
| Interaction | LGALS8 interactions | 5.45e-06 | 174 | 111 | 8 | int:LGALS8 | |
| Interaction | AP3S2 interactions | 1.61e-05 | 28 | 111 | 4 | int:AP3S2 | |
| Cytoband | 1q44 | 2.57e-04 | 110 | 127 | 4 | 1q44 | |
| Cytoband | 5p15.3 | 3.37e-04 | 10 | 127 | 2 | 5p15.3 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1q44 | 4.57e-04 | 128 | 127 | 4 | chr1q44 | |
| GeneFamily | Solute carriers | SLC38A5 SLC7A6 SLCO1B7 SLC6A2 SLC38A1 SLC6A3 SLCO5A1 SLC24A2 SLC16A14 SLC28A1 SLC13A5 SLC38A8 SLC35A5 SLC23A3 | 3.16e-08 | 395 | 99 | 14 | 752 |
| GeneFamily | Olfactory receptors, family 2 | 2.86e-06 | 113 | 99 | 7 | 149 | |
| GeneFamily | ATPases Ca2+ transporting | 1.31e-05 | 9 | 99 | 3 | 1209 | |
| GeneFamily | Anoctamins | 1.86e-05 | 10 | 99 | 3 | 865 | |
| GeneFamily | Taste 2 receptors | 6.00e-05 | 39 | 99 | 4 | 1162 | |
| GeneFamily | Hydroxy-carboxylic acid receptors | 8.87e-05 | 3 | 99 | 2 | 200 | |
| GeneFamily | Adhesion G protein-coupled receptors, subfamily F | 2.94e-04 | 5 | 99 | 2 | 916 | |
| GeneFamily | Atypical chemokine receptors | 4.39e-04 | 6 | 99 | 2 | 1090 | |
| GeneFamily | Cyclic nucleotide gated channels | 1.30e-03 | 10 | 99 | 2 | 250 | |
| GeneFamily | Chloride voltage-gated channels | 1.30e-03 | 10 | 99 | 2 | 302 | |
| GeneFamily | ATP binding cassette subfamily C | 2.23e-03 | 13 | 99 | 2 | 807 | |
| GeneFamily | CD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing | 2.98e-03 | 15 | 99 | 2 | 1296 | |
| GeneFamily | Olfactory receptors, family 10 | 5.68e-03 | 66 | 99 | 3 | 157 | |
| GeneFamily | G protein-coupled receptors, Class A orphans | 9.00e-03 | 78 | 99 | 3 | 262 | |
| ToppCell | facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.73e-09 | 145 | 126 | 8 | 96712c68ab759d7ade0d912581a1a7c25dc6def8 | |
| ToppCell | Influenza_Severe-Neutrophil|World / Disease group and Cell class | 2.89e-08 | 169 | 126 | 8 | 6e8e2580e19c96bcf7fa6a6d8c183df65f428396 | |
| ToppCell | COVID-19_Severe-Neutrophil-|COVID-19_Severe / Disease condition and Cell class | 4.92e-08 | 181 | 126 | 8 | 5e5101195d5ff8c8ea7ddcf0bc4f4e03e64c01e0 | |
| ToppCell | COVID-19_Severe-Neutrophil|COVID-19_Severe / Disease condition and Cell class | 4.92e-08 | 181 | 126 | 8 | aa5e5fb0308b5e2ef918548c85529c9a433c57f5 | |
| ToppCell | Influenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class | 3.89e-07 | 161 | 126 | 7 | 98c95b1b85d5427415af2ca8fb14849e97f6e8b5 | |
| ToppCell | facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 4.06e-07 | 162 | 126 | 7 | bf886e22ff2a20353499004b53f25fb9e6574896 | |
| ToppCell | droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 4.41e-07 | 164 | 126 | 7 | cfe07a1ebed8aecb08d0476db71fe314998d54aa | |
| ToppCell | droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 4.41e-07 | 164 | 126 | 7 | 6d331e74efecb4733d87653f86cd67247be05025 | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 5.85e-07 | 171 | 126 | 7 | ef9397cec7f5c217d34583f26270af7ed7fbcebf | |
| ToppCell | severe_influenza-Neutrophil|severe_influenza / disease group, cell group and cell class (v2) | 6.32e-07 | 173 | 126 | 7 | 615e266419b9f06e964eff73cb466f05451ba0dd | |
| ToppCell | CF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class | 6.83e-07 | 175 | 126 | 7 | 8020c3a34f77e68e8149f87481fb1dddd2ac675e | |
| ToppCell | Influenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class | 1.03e-06 | 186 | 126 | 7 | 1dfcec9196d4db76fba3abc74e85885b1fb98b87 | |
| ToppCell | CD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster | 1.23e-06 | 191 | 126 | 7 | 9454f642c3621370fa23640b631301346b300950 | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.36e-06 | 194 | 126 | 7 | 4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8 | |
| ToppCell | COVID-19_Severe-Neu_0|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients | 1.46e-06 | 196 | 126 | 7 | 4831243fcd680cf4821fa0246e758c3e7c13a962 | |
| ToppCell | BL-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.46e-06 | 196 | 126 | 7 | f64d7fed31e418c55fe946744d78c3cbecec9bbf | |
| ToppCell | COVID-19_Severe-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients | 1.46e-06 | 196 | 126 | 7 | 4fdea41ac7d84f0c52d102d87a5fce620480985e | |
| ToppCell | BL-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.51e-06 | 197 | 126 | 7 | 932a7fae4979b561688e6222505df0f4e510ab11 | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.51e-06 | 197 | 126 | 7 | d2b2eaa6f7294ff56b84a69c8727c7e0f9fd0466 | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.51e-06 | 197 | 126 | 7 | 340ce4fef244176fb52e38ffbcbdfda5ac3467dd | |
| ToppCell | critical-Myeloid-Neutrophil|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.51e-06 | 197 | 126 | 7 | f1248781e71e3a158d06e9ec93eb90dc6d48bcb2 | |
| ToppCell | NS-critical-d_07-13-Myeloid-Neutrophil|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.51e-06 | 197 | 126 | 7 | f38037dfa6c33e9336130d0cc65eaba0f120efb9 | |
| ToppCell | 10x3'2.3-week_17-19-Myeloid_neutrophil-granulo|week_17-19 / cell types per 3 fetal stages;per 3',per 5' | 1.56e-06 | 198 | 126 | 7 | f870e398e996c1f28c8462d87b18f71b20c71011 | |
| ToppCell | moderate-Myeloid-Neutrophil|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.56e-06 | 198 | 126 | 7 | a6306dac34af5783f3a734ef1eaa7a0c03267b4f | |
| ToppCell | 10x5'v1-week_14-16-Myeloid_neutrophil-granulo|week_14-16 / cell types per 3 fetal stages;per 3',per 5' | 1.61e-06 | 199 | 126 | 7 | 5919933c4b842b98fc98685dc8c72c8dd32c6ea3 | |
| ToppCell | 10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5' | 1.61e-06 | 199 | 126 | 7 | 86f2857ce60fbe59375411373ff49c684fd66ad0 | |
| ToppCell | LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA / Treatment groups by lineage, cell group, cell type | 1.67e-06 | 200 | 126 | 7 | fd1b6db3c62f5a205b769ba0e61433dae6285b67 | |
| ToppCell | LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type | 1.67e-06 | 200 | 126 | 7 | 0b7573ec4e9c67c7d11dd8f5011a70bade30e930 | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 2.83e-06 | 139 | 126 | 6 | fa0eedebf53317928022c3bed391ce99a2114f98 | |
| ToppCell | TCGA-Adrenal|World / Sample_Type by Project: Shred V9 | 3.62e-06 | 145 | 126 | 6 | 522ad2bc90b8ec326fcbc7b2250b09566efeeca2 | |
| ToppCell | droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.72e-06 | 169 | 126 | 6 | 7962165cab84af73d20b56eb70b1ed87c94025ef | |
| ToppCell | PND07-Immune-Immune_Myeloid-Granulocytic-Basophil|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 9.02e-06 | 170 | 126 | 6 | bca78719c17355772ad6c53ee75e459faf1d089f | |
| ToppCell | PND07-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 9.02e-06 | 170 | 126 | 6 | 40d863554ec98ae43f76511c1112859688846613 | |
| ToppCell | facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.32e-06 | 171 | 126 | 6 | 6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794 | |
| ToppCell | facs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.32e-06 | 171 | 126 | 6 | e02b5831768dbb1b68998b672e55c9680ab0cc86 | |
| ToppCell | droplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.64e-06 | 172 | 126 | 6 | 1b133be191252e7053faeacf9547730c3ae28d21 | |
| ToppCell | CTRL-Myeloid-Neutrophil|CTRL / Disease state, Lineage and Cell class | 9.64e-06 | 172 | 126 | 6 | ef3a6fe3b7300959f9f71130200c7fb8741c42b0 | |
| ToppCell | droplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.64e-06 | 172 | 126 | 6 | b3c53fd7e50f36de6a8585ae21d04e17932f262c | |
| ToppCell | droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.96e-06 | 173 | 126 | 6 | 1b9b4e165121b08ef15a93fca6bea875cae69f19 | |
| ToppCell | droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.96e-06 | 173 | 126 | 6 | c25f24d7b672c9686d31ebc8d263042282f520fd | |
| ToppCell | IIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster | 9.96e-06 | 173 | 126 | 6 | 4f2843371d18af766c1892529ce286f56c956fde | |
| ToppCell | severe_influenza-Neutrophil|World / disease group, cell group and cell class (v2) | 1.03e-05 | 174 | 126 | 6 | f9f07436b7d3f190800cd85d229f007032f391e1 | |
| ToppCell | saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.12e-05 | 103 | 126 | 5 | 3baaf23a9756be41af3a9b4f720e3ab00f1b674d | |
| ToppCell | facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.17e-05 | 178 | 126 | 6 | fcbbcc44271515de1969b4732b6441c012693d5f | |
| ToppCell | 10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue | 1.25e-05 | 180 | 126 | 6 | 7be7d7a6906fff6dbdecd9cb013d855aba4eda2a | |
| ToppCell | facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.25e-05 | 180 | 126 | 6 | bf8d13d4db1af55b8c9fe16aaccf8743e000e005 | |
| ToppCell | facs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.25e-05 | 180 | 126 | 6 | 839defb40f7cfb2711e9025194de636533f51bcd | |
| ToppCell | facs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.25e-05 | 180 | 126 | 6 | 82965ed1b72a1873c24dd4553d39681596057316 | |
| ToppCell | facs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.29e-05 | 181 | 126 | 6 | 7286700396676fdc41d9723979b8b408177aceb9 | |
| ToppCell | CF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class | 1.37e-05 | 183 | 126 | 6 | da43827952e6fdee2ce94648c316182f272b321c | |
| ToppCell | NS-moderate-d_07-13-Myeloid-Neutrophil|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.41e-05 | 184 | 126 | 6 | 4c7d05f1a4556b13cedbaaf88d67ac32d09b109b | |
| ToppCell | mild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 1.41e-05 | 184 | 126 | 6 | 1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5 | |
| ToppCell | COVID_non-vent-Myeloid-Monocytic-Neutrophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass | 1.46e-05 | 185 | 126 | 6 | 2c89af7cdf5306b900a5b8ec4fdfb8210e5667ed | |
| ToppCell | CV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster | 1.46e-05 | 185 | 126 | 6 | a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f | |
| ToppCell | CV-Moderate-7|CV / Virus stimulation, Condition and Cluster | 1.50e-05 | 186 | 126 | 6 | 8571956890fc9894d766ba294a28e376b4aba428 | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.55e-05 | 187 | 126 | 6 | 75bc05a0ba2727fecc236903ace792a28f3d3c9a | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.55e-05 | 187 | 126 | 6 | a0d59bf1043ff5a1e8110b39ecc2d3932675edd4 | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.60e-05 | 188 | 126 | 6 | aa46073e2940dc1d2020b2e259bf0fc06cb990ee | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.60e-05 | 188 | 126 | 6 | 04814b78da936a51a497e23060d19ca0d619e250 | |
| ToppCell | 10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5' | 1.60e-05 | 188 | 126 | 6 | b4d695c373195d389e0a579e9589e87433286b24 | |
| ToppCell | Monocytes-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id | 1.65e-05 | 189 | 126 | 6 | 2164adbe1b0e8e4d39644546b7dfb19e9ea4f7b9 | |
| ToppCell | COVID-19_Severe-Myeloid_G-Neutrophil|COVID-19_Severe / Disease group, lineage and cell class | 1.65e-05 | 189 | 126 | 6 | a62f4c445ede00d15b74bee65f4e4fb54cfd4d32 | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.65e-05 | 189 | 126 | 6 | f6b2b4824505f0119a017fdb73c55418fb651645 | |
| ToppCell | cellseq-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.65e-05 | 189 | 126 | 6 | fedab592be1d6520325b8c1b659b0a4dc3f4fe4d | |
| ToppCell | PBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09) | 1.65e-05 | 189 | 126 | 6 | db8e314ce95c32542bb4015a77032a33211fea0b | |
| ToppCell | saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.75e-05 | 191 | 126 | 6 | 47156e5f1d790707f42f6283104a44b33af613e5 | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.75e-05 | 191 | 126 | 6 | 4d7f6216958fb202426b7a102e74682105ce7fca | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.75e-05 | 191 | 126 | 6 | e979f6768065b8b3e522d66999ca794d844eccb4 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.75e-05 | 191 | 126 | 6 | 63d4226a8b59f648bdc9f41e4b2d750dfa342034 | |
| ToppCell | COVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type | 1.80e-05 | 192 | 126 | 6 | 441cd1ec171f643b28e1f6f9c04def629cc7391b | |
| ToppCell | NS-moderate-d_16-33-Myeloid-Neutrophil|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.80e-05 | 192 | 126 | 6 | 545c3990cbe3c04bfd95a0ab7499d2c4af509be1 | |
| ToppCell | NS-critical-d_0-4-Myeloid-Neutrophil|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.80e-05 | 192 | 126 | 6 | 3db74359c30172a51177e00eac1f48f483e15578 | |
| ToppCell | moderate-Myeloid-Neutrophil|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.80e-05 | 192 | 126 | 6 | 8105408400dac5dcb0ce62b558433257559c9f09 | |
| ToppCell | COVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.80e-05 | 192 | 126 | 6 | 0b9d22a222f1201e375f8e55cace9ef939febae4 | |
| ToppCell | severe-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 1.85e-05 | 193 | 126 | 6 | f4d43dfbf4115dd0f843ea5cf08049220342a047 | |
| ToppCell | PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.85e-05 | 193 | 126 | 6 | b044fca95f519ff2ceb378afe40a95911931a29e | |
| ToppCell | medial-Hematologic-Nonclassical_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.91e-05 | 194 | 126 | 6 | ac203d388a3a3884e316dec0dcbd408e43c6ef6c | |
| ToppCell | distal-Hematologic-Nonclassical_Monocyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.91e-05 | 194 | 126 | 6 | f1cabb198ab32deaf299899c5e8f42d861b8c574 | |
| ToppCell | medial-2-Hematologic-Nonclassical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.91e-05 | 194 | 126 | 6 | 202e5070728191c46161fa7d931f00be1c7559d4 | |
| ToppCell | medial-Hematologic-Nonclassical_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.91e-05 | 194 | 126 | 6 | 002cd317732fc6b0d9a72fb46199f71db5a638a7 | |
| ToppCell | mild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 1.91e-05 | 194 | 126 | 6 | ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.91e-05 | 194 | 126 | 6 | 607b5d194ba56efa9b106f10f89368fc103712a0 | |
| ToppCell | saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.91e-05 | 194 | 126 | 6 | f5367072b259ae170cf0df3d4d871ab41be29d29 | |
| ToppCell | cellseq-Immune-Immune_Myeloid-pMON-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.96e-05 | 195 | 126 | 6 | 2cb435dae2691e1250e26e59f9b8fb652a0c383e | |
| ToppCell | distal-Hematologic-Nonclassical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.96e-05 | 195 | 126 | 6 | 935461e849ca4d17627341b3ae5124d497793a91 | |
| ToppCell | cellseq-Immune-Immune_Myeloid-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.96e-05 | 195 | 126 | 6 | 217908cb53016a6cb51f1bc3fc752c8df650df71 | |
| ToppCell | Control-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class | 1.96e-05 | 195 | 126 | 6 | b4444b67a709e82b8e2ee510924c3152cb88b051 | |
| ToppCell | control-Myeloid-Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 2.02e-05 | 196 | 126 | 6 | 9c8623232c47af5de9f360fd5c5113362e37c6c9 | |
| ToppCell | saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 2.02e-05 | 196 | 126 | 6 | fe8d3f45a64323947c36b127355d5940eb56c0ca | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.02e-05 | 196 | 126 | 6 | 77feb22fd0b0b1df03375da472134412e9e69c90 | |
| ToppCell | NS-moderate-d_16-33-Myeloid|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 2.02e-05 | 196 | 126 | 6 | dc8483625f1188771eb98bd94757b25163b2fc2f | |
| ToppCell | mild-Myeloid-Neutrophils_4|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 2.02e-05 | 196 | 126 | 6 | f8c98cded5550843322b1711e1a57c7e88cae861 | |
| ToppCell | saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 2.02e-05 | 196 | 126 | 6 | 526d037bb12d81f1c235c60ddc787fbad0bbad77 | |
| ToppCell | NS-moderate-d_16-33|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 2.02e-05 | 196 | 126 | 6 | 85301941e0c04a237b307f56c87dc06760015a5d | |
| ToppCell | wk_15-18-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 2.02e-05 | 196 | 126 | 6 | aa53ae1e5d08d31cfd81b7fae46c2b5d21d4f9b2 | |
| ToppCell | 10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5' | 2.14e-05 | 198 | 126 | 6 | 82f6ac18c3a6487f03579b5c247844f1c115c2be | |
| ToppCell | 10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5' | 2.14e-05 | 198 | 126 | 6 | e76061e66f6d60f5735962aa7777dda8958caed9 | |
| ToppCell | critical-Myeloid-Neutrophil|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 2.14e-05 | 198 | 126 | 6 | 4da73dc3acb29d70b160903600d2bf7fdab34333 | |
| ToppCell | LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type | 2.20e-05 | 199 | 126 | 6 | 8c2ab13b5fffbab3da37041a7000d6537fc4db09 | |
| ToppCell | 10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5' | 2.20e-05 | 199 | 126 | 6 | caf2e050b21e7a16ce4e51b3f135debd06810231 | |
| Computational | GPCR signaling pathways (immune and neuro). | 1.00e-04 | 90 | 56 | 5 | MODULE_375 | |
| Computational | Genes in the cancer module 236. | 1.03e-04 | 18 | 56 | 3 | MODULE_236 | |
| Computational | Membranal receptors. | ABCA1 ICAM3 PTAFR IL18R1 SLC6A2 SLC6A3 HCAR3 FCER1A KCNQ3 C5AR1 | 2.93e-04 | 517 | 56 | 10 | MODULE_64 |
| Computational | Genes in the cancer module 289. | 4.50e-04 | 124 | 56 | 5 | MODULE_289 | |
| Drug | sodium | CACNA1D HCAR2 OSTM1 HCN1 SLC38A5 TCIRG1 HUWE1 SLC7A6 ADCY2 SLC6A2 SLC38A1 SLC6A3 HCAR3 CLCN3 TSPAN16 KCNT2 SLC24A2 SLC28A1 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.20e-09 | 944 | 123 | 23 | CID000000923 |
| Drug | verapamil | CACNA1D HCAR2 ABCA1 TRPA1 CYP17A1 ABCC5 APOL1 CHRM2 ADCY2 HCAR3 CLCN3 KCNT2 KCNQ3 ABCC2 ATP2A1 ATP2A2 ATP2B3 | 1.26e-09 | 490 | 123 | 17 | CID000002520 |
| Drug | epicholesterol | NPC1 HCAR2 ABCA1 CYP17A1 MC2R APOL1 CHRM2 ADCY2 HCAR3 MBTPS2 LRP5 SLC13A5 ABCC2 ATP2A1 ATP2A2 ATP2B3 SORL1 | 5.91e-08 | 636 | 123 | 17 | CID000000304 |
| Drug | potassium | CACNA1D HCAR2 TRPA1 HCN1 CYP17A1 SLC38A5 TCIRG1 GRM8 CHRM2 ADCY2 SLC38A1 HCAR3 CLCN3 KCNT2 CLCN7 SLC24A2 KCNQ3 HRH4 ATP2A1 ATP2A2 ATP2B3 | 1.02e-07 | 1008 | 123 | 21 | CID000000813 |
| Drug | AC1L9NAZ | 1.26e-07 | 198 | 123 | 10 | CID000449606 | |
| Drug | Verteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A | 2.22e-07 | 160 | 123 | 9 | 6133_DN | |
| Drug | lanthanum | 7.62e-07 | 136 | 123 | 8 | CID000023926 | |
| Drug | compound 48/80 | 1.68e-06 | 151 | 123 | 8 | CID000104735 | |
| Drug | gamma-aminobutyric acid | CACNA1D HCAR2 TRPA1 MRGPRD ICAM3 GRM8 CHRM2 SLC38A1 SLC6A3 HCAR3 CLCN3 CLCN7 SEMA6A | 1.80e-06 | 474 | 123 | 13 | CID000000119 |
| Drug | hemicholinium-3 | 4.11e-06 | 78 | 123 | 6 | CID000003585 | |
| Drug | myo-inositol | CACNA1D TRPA1 PTAFR GRM8 CHRM2 ADCY2 CSE1L FCER1A P2RY4 VNN2 HRH4 ATP2A1 ATP2A2 ATP2B3 GPR176 GPR45 | 7.83e-06 | 811 | 123 | 16 | CID000000892 |
| Drug | halothane | CACNA1D HCAR2 TRPA1 CYP17A1 CHRM2 ADCY2 HCAR3 ATP2A1 ATP2A2 ATP2B3 | 8.18e-06 | 314 | 123 | 10 | CID000003562 |
| Drug | Cocaine | 8.45e-06 | 8 | 123 | 3 | DB00907 | |
| Drug | Nicotinic Acids | 8.45e-06 | 8 | 123 | 3 | ctd:D009539 | |
| Drug | 3-isoreserpine | 9.22e-06 | 190 | 123 | 8 | CID000005052 | |
| Drug | pempidine | 9.40e-06 | 25 | 123 | 4 | CID000006603 | |
| Drug | AC1L9NBR | 1.07e-05 | 92 | 123 | 6 | CID000449625 | |
| Drug | Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A | 1.24e-05 | 198 | 123 | 8 | 5443_UP | |
| Drug | Adrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A | 1.24e-05 | 198 | 123 | 8 | 5464_UP | |
| Drug | AC1L1KS5 | CACNA1D HDAC11 TRPA1 GRM8 CHRM2 C5AR1 ATP2A1 ATP2A2 ATP2B3 GPR45 | 1.40e-05 | 334 | 123 | 10 | CID000005631 |
| Drug | Calcium | CACNA1D HCAR2 TRPA1 ADGRL1 PTAFR HCAR3 P2RY4 SLC24A2 HRH4 ABCC2 ATP2A1 ATP2A2 | 1.52e-05 | 493 | 123 | 12 | ctd:D002118 |
| Drug | octaethylene glycol | 1.74e-05 | 29 | 123 | 4 | CID000078798 | |
| Drug | 1sqc | 1.80e-05 | 10 | 123 | 3 | CID000444279 | |
| Drug | 6-methylpurine-2'-deoxyriboside | 1.98e-05 | 61 | 123 | 5 | CID000097184 | |
| Drug | tetrahydrodeoxycortisol | 2.28e-05 | 31 | 123 | 4 | CID000010593 | |
| Drug | 2,5-dimethylquinone | 2.46e-05 | 11 | 123 | 3 | CID000008718 | |
| Drug | oxotremorine | 2.68e-05 | 108 | 123 | 6 | CID000004630 | |
| Drug | 4-iodobenzoylchloride | 2.89e-05 | 2 | 123 | 2 | CID000074373 | |
| Drug | Bupropion | 2.89e-05 | 2 | 123 | 2 | DB01156 | |
| Drug | aspirin chloride | 2.89e-05 | 2 | 123 | 2 | CID000079668 | |
| Drug | Diethylpropion | 2.89e-05 | 2 | 123 | 2 | DB00937 | |
| Drug | Phenmetrazine | 2.89e-05 | 2 | 123 | 2 | DB00830 | |
| Drug | RTI-4793-14 | 2.89e-05 | 2 | 123 | 2 | CID000192688 | |
| Drug | 1vyq | 3.27e-05 | 12 | 123 | 3 | CID004369390 | |
| Drug | l-Lobeline | 3.32e-05 | 34 | 123 | 4 | CID000003945 | |
| Drug | (+/-)-Epibatidine | 3.73e-05 | 35 | 123 | 4 | CID000001204 | |
| Drug | iloperidone | 4.18e-05 | 36 | 123 | 4 | CID000071360 | |
| Drug | TMB-8 | 4.89e-05 | 176 | 123 | 7 | CID000005494 | |
| Drug | fluo-3 | 5.33e-05 | 122 | 123 | 6 | CID000104978 | |
| Drug | p-hydroxyhippuric acid | 5.36e-05 | 14 | 123 | 3 | CID000151012 | |
| Drug | caffeine | CACNA1D HCAR2 TRPA1 CYP17A1 GRM8 CHRM2 ADCY2 HCAR3 P2RY4 ATP2A1 ATP2A2 ATP2B3 | 5.44e-05 | 562 | 123 | 12 | CID000002519 |
| Drug | D-myo-inositol-1,4,5-triphosphate | CACNA1D TRPA1 PTAFR GRM8 CHRM2 ADCY2 FCER1A P2RY4 HRH4 ATP2A1 ATP2A2 ATP2B3 | 6.02e-05 | 568 | 123 | 12 | CID000000806 |
| Drug | carbonyl cyanide m-chlorophenylhydrazone | 6.11e-05 | 125 | 123 | 6 | CID000002603 | |
| Drug | pseudococaine | HCAR2 DOLPP1 ACKR4 GRM8 CHRM2 ADCY2 SLC6A2 SLC6A3 HCAR3 ATP2A1 ATP2A2 ATP2B3 | 6.23e-05 | 570 | 123 | 12 | CID000002826 |
| Drug | doxepin | 6.38e-05 | 40 | 123 | 4 | CID000003158 | |
| Drug | NSC172130 | 6.68e-05 | 15 | 123 | 3 | CID000003155 | |
| Drug | C12E8 | 7.74e-05 | 42 | 123 | 4 | CID000123921 | |
| Drug | AC1Q3ZOL | 8.18e-05 | 258 | 123 | 8 | CID000002376 | |
| Drug | D-161 compound | 8.65e-05 | 3 | 123 | 2 | ctd:C532102 | |
| Drug | 6-fluorodopamine | 8.65e-05 | 3 | 123 | 2 | CID000122236 | |
| Drug | Mazindol | 8.65e-05 | 3 | 123 | 2 | DB00579 | |
| Drug | Methylphenidate | 8.65e-05 | 3 | 123 | 2 | DB00422 | |
| Drug | Duloxetine | 8.65e-05 | 3 | 123 | 2 | DB00476 | |
| Drug | 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone | 8.65e-05 | 3 | 123 | 2 | ctd:C569113 | |
| Drug | Venlafaxine | 8.65e-05 | 3 | 123 | 2 | DB00285 | |
| Drug | 4-fluoroamphetamine | 8.65e-05 | 3 | 123 | 2 | ctd:C040639 | |
| Drug | Sibutramine | 8.65e-05 | 3 | 123 | 2 | DB01105 | |
| Drug | RTI-219 | 8.65e-05 | 3 | 123 | 2 | CID010524711 | |
| Drug | 2-(4-bromo-2,5-dimethoxyphenyl)ethylamine | 8.65e-05 | 3 | 123 | 2 | ctd:C079321 | |
| Drug | 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone | 8.65e-05 | 3 | 123 | 2 | ctd:C000592273 | |
| Drug | difluoropine | 8.65e-05 | 3 | 123 | 2 | CID000190851 | |
| Drug | Dexmethylphenidate | 8.65e-05 | 3 | 123 | 2 | DB06701 | |
| Drug | 2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine | 8.65e-05 | 3 | 123 | 2 | ctd:C000595926 | |
| Drug | 1,4-diazabicyclo[3.3.1]nonane | 8.65e-05 | 3 | 123 | 2 | CID015140257 | |
| Drug | 5-(2-aminopropyl)benzofuran | 8.65e-05 | 3 | 123 | 2 | ctd:C000608250 | |
| Drug | 4-methoxymethamphetamine | 8.65e-05 | 3 | 123 | 2 | ctd:C060169 | |
| Drug | 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine | 8.65e-05 | 3 | 123 | 2 | ctd:C554181 | |
| Drug | XeC compound | 9.31e-05 | 84 | 123 | 5 | CID000005701 | |
| Drug | Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A | 9.33e-05 | 195 | 123 | 7 | 4792_UP | |
| Drug | Flecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A | 9.63e-05 | 196 | 123 | 7 | 3761_UP | |
| Drug | AC1L88YH | 9.90e-05 | 17 | 123 | 3 | CID000374551 | |
| Drug | Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A | 1.09e-04 | 200 | 123 | 7 | 6071_DN | |
| Drug | phentolamine | 1.09e-04 | 200 | 123 | 7 | CID000005775 | |
| Drug | mianserin | 1.10e-04 | 87 | 123 | 5 | CID000004184 | |
| Drug | atropine sulfate | 1.15e-04 | 347 | 123 | 9 | CID000003661 | |
| Drug | sulfadoxine-pyrimethamine | 1.18e-04 | 18 | 123 | 3 | CID000065404 | |
| Drug | mecamylamine | 1.22e-04 | 89 | 123 | 5 | CID000004032 | |
| Drug | nimodipine | 1.39e-04 | 145 | 123 | 6 | CID000004497 | |
| Drug | femoxitine | 1.40e-04 | 19 | 123 | 3 | CID000043103 | |
| Drug | zotepine | 1.42e-04 | 49 | 123 | 4 | CID000005736 | |
| Drug | AC1MMLID | 1.43e-04 | 92 | 123 | 5 | CID000013245 | |
| Drug | Bay K 8644 | 1.67e-04 | 150 | 123 | 6 | CID000002303 | |
| Drug | ethylphenidate | 1.72e-04 | 4 | 123 | 2 | CID003080846 | |
| Drug | Fluorescent Dyes | 1.72e-04 | 4 | 123 | 2 | ctd:D005456 | |
| Drug | Chlorpheniramine | 1.72e-04 | 4 | 123 | 2 | DB01114 | |
| Drug | Niacin | 1.72e-04 | 4 | 123 | 2 | DB00627 | |
| Drug | Biogenic Monoamines | 1.72e-04 | 4 | 123 | 2 | ctd:D015306 | |
| Drug | 4-(4-Chlorophenyl)piperidine | 1.72e-04 | 4 | 123 | 2 | CID001203613 | |
| Drug | butriptyline | 1.72e-04 | 4 | 123 | 2 | CID000021771 | |
| Drug | norsalsolinol | 1.72e-04 | 4 | 123 | 2 | CID000036937 | |
| Drug | indatraline | 1.72e-04 | 4 | 123 | 2 | ctd:C418119 | |
| Drug | AC1L1KC5 | CACNA1D HCAR2 TRPA1 GRM8 CHRM2 HCAR3 MBTPS2 P2RY4 ATP2A1 ATP2A2 ATP2B3 | 1.73e-04 | 541 | 123 | 11 | CID000005428 |
| Drug | DCCD | 1.73e-04 | 151 | 123 | 6 | CID000010868 | |
| Drug | procaine | 1.86e-04 | 153 | 123 | 6 | CID000004914 | |
| Drug | indo-1 | 2.02e-04 | 99 | 123 | 5 | CID000105060 | |
| Drug | xanthohumol | 2.08e-04 | 54 | 123 | 4 | ctd:C104536 | |
| Drug | glutamate | CACNA1D HCAR2 TRPA1 HCN1 SLC7A6 GRM8 CHRM2 ADCY2 SLC38A1 SLC6A3 HCAR3 CLCN3 CLCN7 SLC24A2 SEMA6A | 2.17e-04 | 962 | 123 | 15 | CID000000611 |
| Drug | ivermectin | 2.22e-04 | 101 | 123 | 5 | CID006435110 | |
| Drug | glibenclamide | 2.35e-04 | 382 | 123 | 9 | CID000003488 | |
| Drug | 2-(aminomethyl)pyrrolidine | 2.45e-04 | 161 | 123 | 6 | CID000072032 | |
| Disease | Autosomal dominant osteopetrosis | 1.61e-05 | 2 | 119 | 2 | cv:C4272579 | |
| Disease | Tremor, Rubral | 3.45e-05 | 16 | 119 | 3 | C0750940 | |
| Disease | Ataxia, Appendicular | 3.45e-05 | 16 | 119 | 3 | C0750937 | |
| Disease | Ataxia, Motor | 3.45e-05 | 16 | 119 | 3 | C0278161 | |
| Disease | Ataxia, Sensory | 3.45e-05 | 16 | 119 | 3 | C0240991 | |
| Disease | Abnormal coordination | 3.45e-05 | 16 | 119 | 3 | C0520966 | |
| Disease | Ataxia, Truncal | 3.45e-05 | 16 | 119 | 3 | C0427190 | |
| Disease | Brody myopathy (implicated_via_orthology) | 4.83e-05 | 3 | 119 | 2 | DOID:0050692 (implicated_via_orthology) | |
| Disease | Osteopetrosis, Autosomal Recessive 6 | 4.83e-05 | 3 | 119 | 2 | C1969093 | |
| Disease | sick sinus syndrome (implicated_via_orthology) | 4.83e-05 | 3 | 119 | 2 | DOID:13884 (implicated_via_orthology) | |
| Disease | Osteopetrosis - intermediate type | 4.83e-05 | 3 | 119 | 2 | C0432261 | |
| Disease | Schizophrenia | HCAR2 ABCA1 GRM8 IL18R1 CHRM2 SLC6A2 SLC6A3 HCAR3 KCNQ3 ADGRF4 ATP2A2 KPNA1 SLC23A3 | 5.95e-05 | 883 | 119 | 13 | C0036341 |
| Disease | Mood Disorders | 6.35e-05 | 168 | 119 | 6 | C0525045 | |
| Disease | Gilles de la Tourette syndrome (implicated_via_orthology) | 9.63e-05 | 4 | 119 | 2 | DOID:11119 (implicated_via_orthology) | |
| Disease | Infantile malignant osteopetrosis | 9.63e-05 | 4 | 119 | 2 | C1318518 | |
| Disease | Ataxia | 1.38e-04 | 25 | 119 | 3 | C0004134 | |
| Disease | bilirubin metabolic disorder (implicated_via_orthology) | 1.60e-04 | 5 | 119 | 2 | DOID:2741 (implicated_via_orthology) | |
| Disease | metabolic syndrome | 1.65e-04 | 200 | 119 | 6 | EFO_0000195 | |
| Disease | attention deficit hyperactivity disorder (implicated_via_orthology) | 1.95e-04 | 28 | 119 | 3 | DOID:1094 (implicated_via_orthology) | |
| Disease | Gilles de la Tourette syndrome (is_implicated_in) | 2.39e-04 | 6 | 119 | 2 | DOID:11119 (is_implicated_in) | |
| Disease | Conn Syndrome | 2.39e-04 | 6 | 119 | 2 | C1384514 | |
| Disease | Sick Sinus Syndrome | 2.39e-04 | 6 | 119 | 2 | C0037052 | |
| Disease | Hyperaldosteronism | 2.39e-04 | 6 | 119 | 2 | C0020428 | |
| Disease | heart conduction disease (implicated_via_orthology) | 2.91e-04 | 32 | 119 | 3 | DOID:10273 (implicated_via_orthology) | |
| Disease | neutropenia (implicated_via_orthology) | 3.34e-04 | 7 | 119 | 2 | DOID:1227 (implicated_via_orthology) | |
| Disease | osteopetrosis (implicated_via_orthology) | 3.34e-04 | 7 | 119 | 2 | DOID:13533 (implicated_via_orthology) | |
| Disease | alcohol-related neurodevelopmental disorder (implicated_via_orthology) | 4.44e-04 | 8 | 119 | 2 | DOID:0050667 (implicated_via_orthology) | |
| Disease | glucose metabolism decline measurement, cingulate cortex measurement | 5.70e-04 | 9 | 119 | 2 | EFO_0007738, EFO_0009392 | |
| Disease | 5-acetylamino-6-formylamino-3-methyluracil measurement | 5.70e-04 | 9 | 119 | 2 | EFO_0800950 | |
| Disease | Bipolar Disorder | 7.21e-04 | 477 | 119 | 8 | C0005586 | |
| Disease | Generalized seizures | 7.60e-04 | 101 | 119 | 4 | C0234533 | |
| Disease | Clonic Seizures | 7.60e-04 | 101 | 119 | 4 | C0234535 | |
| Disease | Convulsive Seizures | 7.60e-04 | 101 | 119 | 4 | C0751494 | |
| Disease | Seizures, Sensory | 7.60e-04 | 101 | 119 | 4 | C0751496 | |
| Disease | Non-epileptic convulsion | 7.60e-04 | 101 | 119 | 4 | C0751056 | |
| Disease | Atonic Absence Seizures | 7.60e-04 | 101 | 119 | 4 | C0751123 | |
| Disease | Complex partial seizures | 7.60e-04 | 101 | 119 | 4 | C0149958 | |
| Disease | Single Seizure | 7.60e-04 | 101 | 119 | 4 | C0751110 | |
| Disease | Nonepileptic Seizures | 7.60e-04 | 101 | 119 | 4 | C3495874 | |
| Disease | Visual seizure | 7.60e-04 | 101 | 119 | 4 | C0270824 | |
| Disease | Epileptic drop attack | 7.60e-04 | 101 | 119 | 4 | C0270846 | |
| Disease | Vertiginous seizure | 7.60e-04 | 101 | 119 | 4 | C0422855 | |
| Disease | Gustatory seizure | 7.60e-04 | 101 | 119 | 4 | C0422854 | |
| Disease | Seizures, Somatosensory | 7.60e-04 | 101 | 119 | 4 | C0422850 | |
| Disease | Olfactory seizure | 7.60e-04 | 101 | 119 | 4 | C0422853 | |
| Disease | Seizures, Auditory | 7.60e-04 | 101 | 119 | 4 | C0422852 | |
| Disease | Generalized Absence Seizures | 7.60e-04 | 101 | 119 | 4 | C4505436 | |
| Disease | Jacksonian Seizure | 7.60e-04 | 101 | 119 | 4 | C0022333 | |
| Disease | Epileptic Seizures | 7.60e-04 | 101 | 119 | 4 | C4317109 | |
| Disease | Absence Seizures | 7.88e-04 | 102 | 119 | 4 | C4316903 | |
| Disease | Convulsions | 7.88e-04 | 102 | 119 | 4 | C4048158 | |
| Disease | Tonic Seizures | 7.88e-04 | 102 | 119 | 4 | C0270844 | |
| Disease | saturated fatty acids measurement | 8.02e-04 | 45 | 119 | 3 | EFO_0022304 | |
| Disease | Seizures, Focal | 8.47e-04 | 104 | 119 | 4 | C0751495 | |
| Disease | Myoclonic Seizures | 8.47e-04 | 104 | 119 | 4 | C4317123 | |
| Disease | Tonic - clonic seizures | 8.47e-04 | 104 | 119 | 4 | C0494475 | |
| Disease | 5-acetylamino-6-amino-3-methyluracil measurement | 8.66e-04 | 11 | 119 | 2 | EFO_0800951 | |
| Disease | calcium measurement | 1.03e-03 | 628 | 119 | 9 | EFO_0004838 | |
| Disease | N-acetylputrescine measurement | 1.04e-03 | 12 | 119 | 2 | EFO_0800127 | |
| Disease | glycochenodeoxycholate glucuronide (1) measurement | 1.22e-03 | 13 | 119 | 2 | EFO_0800474 | |
| Disease | triglycerides in HDL measurement | 1.29e-03 | 53 | 119 | 3 | EFO_0022317 | |
| Disease | triacylglycerol 52:1 measurement | 1.42e-03 | 14 | 119 | 2 | EFO_0010413 | |
| Disease | Autosomal recessive limb-girdle muscular dystrophy | 1.42e-03 | 14 | 119 | 2 | cv:C2931907 | |
| Disease | early cardiac repolarization measurement | 1.42e-03 | 14 | 119 | 2 | EFO_0004885 | |
| Disease | triglycerides in very large HDL measurement | 1.44e-03 | 55 | 119 | 3 | EFO_0022324 | |
| Disease | triglycerides in LDL measurement | 1.52e-03 | 56 | 119 | 3 | EFO_0022320 | |
| Disease | Sinus Node Dysfunction (disorder) | 1.64e-03 | 15 | 119 | 2 | C0428908 | |
| Disease | insulin resistance | 1.76e-03 | 59 | 119 | 3 | EFO_0002614 | |
| Disease | focal segmental glomerulosclerosis | 1.87e-03 | 16 | 119 | 2 | EFO_0004236 | |
| Disease | Parkinson disease | 1.96e-03 | 321 | 119 | 6 | MONDO_0005180 | |
| Disease | metabolite measurement | 1.99e-03 | 560 | 119 | 8 | EFO_0004725 | |
| Disease | HDL cholesterol change measurement, physical activity | 2.03e-03 | 62 | 119 | 3 | EFO_0003940, EFO_0007805 | |
| Disease | triglycerides in medium LDL measurement | 2.03e-03 | 62 | 119 | 3 | EFO_0022322 | |
| Disease | X-21441 measurement | 2.11e-03 | 17 | 119 | 2 | EFO_0800814 | |
| Disease | Colorectal Carcinoma | 2.20e-03 | 702 | 119 | 9 | C0009402 | |
| Disease | triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement | 2.23e-03 | 225 | 119 | 5 | EFO_0008317, EFO_0020947 | |
| Disease | triglycerides in small LDL measurement | 2.33e-03 | 65 | 119 | 3 | EFO_0022323 | |
| Disease | Pseudopelade | 2.64e-03 | 19 | 119 | 2 | C0086873 | |
| Disease | schizophrenia (implicated_via_orthology) | 2.65e-03 | 68 | 119 | 3 | DOID:5419 (implicated_via_orthology) | |
| Disease | ceramide measurement | 2.69e-03 | 235 | 119 | 5 | EFO_0010222 | |
| Disease | polymyositis | 2.92e-03 | 20 | 119 | 2 | EFO_0003063 | |
| Disease | attention deficit hyperactivity disorder (is_implicated_in) | 2.92e-03 | 20 | 119 | 2 | DOID:1094 (is_implicated_in) | |
| Disease | triglyceride measurement, phospholipid measurement | 2.94e-03 | 146 | 119 | 4 | EFO_0004530, EFO_0004639 | |
| Disease | cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement | 3.10e-03 | 243 | 119 | 5 | EFO_0004612, EFO_0020944 | |
| Disease | resting heart rate | 3.16e-03 | 149 | 119 | 4 | EFO_0004351 | |
| Disease | osteoporosis | 3.24e-03 | 73 | 119 | 3 | EFO_0003882 | |
| Disease | Attention Deficit Disorder | 3.53e-03 | 22 | 119 | 2 | C0041671 | |
| Disease | Minimal Brain Dysfunction | 3.53e-03 | 22 | 119 | 2 | C1321905 | |
| Disease | progranulin measurement | 3.53e-03 | 22 | 119 | 2 | EFO_0004625 | |
| Disease | complement factor H-like 1 protein measurement | 3.53e-03 | 22 | 119 | 2 | EFO_0600092 | |
| Disease | aspartate aminotransferase measurement | 3.66e-03 | 904 | 119 | 10 | EFO_0004736 | |
| Disease | Mental Depression | 3.74e-03 | 254 | 119 | 5 | C0011570 | |
| Disease | risk-taking behaviour | 3.85e-03 | 764 | 119 | 9 | EFO_0008579 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VIAFAIPLLDTKVFV | 161 | P60509 | |
| FFIPLLVVILFAVDT | 206 | P12319 | |
| LVVILFAVDTGLFIS | 211 | P12319 | |
| AFIVAFTSDIIPRLV | 746 | Q75V66 | |
| VAIAILVPFFALIFA | 3631 | Q7Z407 | |
| AFVVPALAIVAVNFV | 746 | Q5T601 | |
| SFIGPVSFVIVVNLV | 1006 | O94910 | |
| ALALNVPVFVVVTKI | 296 | O00178 | |
| SFAVATITEIPPVIF | 86 | Q96DB2 | |
| VVPATLVIIIFICFQ | 1711 | O95477 | |
| AFAIPAFVIVAVNLI | 561 | Q8IZF3 | |
| FEVVFIVLVAGSLSL | 21 | P08172 | |
| TSFLIPSSVIGVIVF | 371 | Q9NQ90 | |
| AFVIAITSDFIPRLV | 786 | Q32M45 | |
| FVSVIQTEVPPLFVI | 66 | Q9Y2T2 | |
| PDILALVIFAVVFLV | 36 | P21730 | |
| VFEDVPVGTIILTVT | 2411 | Q9H251 | |
| TAFVEPFVILLILIA | 86 | O14983 | |
| KFFIIGVTVLVVAVP | 416 | Q16720 | |
| FVPFIVFVSIATLLV | 941 | Q04656 | |
| VREFAKVFLPVFLTI | 36 | Q9NPB9 | |
| FVAVIQTEVPPLFVI | 66 | P53677 | |
| HVVAVVFITVPFLLI | 191 | Q8NH19 | |
| ELFVASILFLIVPVS | 201 | Q8NGZ5 | |
| QVAVASVFILVVPLS | 196 | O95918 | |
| IILIEFTPVTDFTFL | 471 | Q13478 | |
| VAITVPLVVISAFAT | 301 | Q8NFM7 | |
| LITVAIIAIFTFVEP | 111 | Q969X1 | |
| IIAIFTFVEPVSAFV | 116 | Q969X1 | |
| LSLSPVFVIVGFVTL | 36 | Q86YN1 | |
| ITTVIVPVVVVFLFL | 211 | Q14439 | |
| VAIVFVICFLPSVVV | 236 | Q8TDS4 | |
| GAAVVITILKVFFPV | 276 | Q9NU53 | |
| LDIFVLIASVPVVAV | 201 | O43525 | |
| VLAALEFPTVATVEI | 1861 | Q5SZK8 | |
| IVPEAFLVFTSRAAI | 641 | O75197 | |
| FTTPALVVEKDAVFI | 296 | O43237 | |
| FVLVGSVIVAFIEPV | 186 | P51798 | |
| VFSPFVLVIIVFSTL | 571 | Q63HM2 | |
| IGTSVVIIPFAILLF | 326 | Q8N743 | |
| PTRLFVVVLASVLVF | 216 | Q8TDS7 | |
| LLSILVFVPSAVVVA | 161 | Q6UWV2 | |
| VLIPSIVITVIFLFF | 11 | Q86UP2 | |
| VIFVFQLTPVLVSVV | 546 | Q92887 | |
| ILEIINAVPFIISIF | 141 | Q6UVM3 | |
| EVTNVIFLGVPVLFI | 201 | Q9NQN1 | |
| DTVPVIAVSVFILFL | 281 | Q86WC4 | |
| YQPEEIILVSFVLVF | 376 | Q6PEW0 | |
| IVFSSITVPKFLVDL | 71 | Q8NGJ1 | |
| VPVFVAILGIIATTF | 586 | O00222 | |
| LLATEVVTVFVFQEP | 556 | Q7Z6Z7 | |
| VVTVFVFQEPSLLSS | 561 | Q7Z6Z7 | |
| VVTLVVAVFFAPFGV | 196 | Q9Y5Y3 | |
| FISSIPVDYIFLIVE | 346 | Q9Y3Q4 | |
| FVPVFVAVLLTLGVV | 486 | P32942 | |
| FTEGAAVVVTPFLLI | 201 | Q8NGR3 | |
| VVIFATCVFVLVGPL | 196 | Q6IF42 | |
| TILAVLVAFFVLVPL | 201 | Q5JQS5 | |
| PCFVFVESVLLGIVI | 16 | Q96GM1 | |
| ILPSLTEIDTVVFIF | 396 | Q14397 | |
| PIVIAIFVGVLSFSI | 836 | O15118 | |
| TIAVVLTVFAVCFVP | 246 | P51582 | |
| FIISFKLETDPAIVI | 226 | Q9HAB8 | |
| APIVVVIASVVTFSV | 406 | O15440 | |
| VNLVFFIDSPTVIAV | 356 | P0CG42 | |
| VAFLITVPTALAIFF | 76 | Q08462 | |
| TVPTALAIFFAIFIL | 81 | Q08462 | |
| TAFVEPFVILLILVA | 86 | P16615 | |
| FISSIPVDYIFLIVE | 226 | O60741 | |
| DISFPVFVAVTNVIS | 166 | P05093 | |
| SVVLGFAVPFSIIAV | 216 | P25106 | |
| FPIFLVTLVALVDVD | 526 | Q9Y653 | |
| TDVAPVSFFLVLDVV | 336 | O14791 | |
| NFLSIDLPVVVETFV | 431 | O43462 | |
| KIVRTAELSPFIVFI | 386 | Q00013 | |
| LSAPAVLVVAVAVVV | 66 | Q9HBU6 | |
| DATVAIFVATLLFIV | 356 | Q86YT5 | |
| DFVIVIVGLFSVILE | 201 | Q01668 | |
| DPGFISFAVIITVIS | 206 | Q6NVV3 | |
| ESELFFVSVIILLVP | 196 | P59922 | |
| VSSFVIFVPIGLIFI | 201 | Q8NHC4 | |
| EFVIFICGVLVLVVP | 216 | Q8NGX6 | |
| ELVLFVVSVLFVVIP | 196 | Q8NGZ4 | |
| EAELFVASVVFLIVP | 196 | Q5TZ20 | |
| IVRTLVFVTPFTFLI | 151 | Q8NH55 | |
| AEFVISRPLVIVGFF | 166 | Q8N807 | |
| AITSFLEFVIPVILV | 176 | Q9H3N8 | |
| PSIFTLVIIAEFIIG | 6 | Q9NYV9 | |
| PIIFSSVVVVLFVIG | 6 | P59538 | |
| PIIFSSLVVVTFVIG | 6 | P59537 | |
| PAFLLFVVVVSIINF | 526 | P23975 | |
| ARSTDVAAVVVPILF | 2131 | Q92673 | |
| INDLVTPFFVVFLSE | 311 | Q9NU19 | |
| VLLVFVSTIANFITP | 656 | O75069 | |
| KLSVVATFLIEIAVP | 226 | Q9BU23 | |
| FLIVFILPLDVSTTI | 46 | Q68DH5 | |
| IVCDEFFVPSLTVIT | 151 | Q9UI40 | |
| DVFPLTSIIAIVHIF | 351 | Q7RTX9 | |
| AVLLAVTLTVPVVLF | 341 | Q8WUX1 | |
| QAEPVEIVAFSVIIL | 26 | Q71RC9 | |
| SVPVLIIHIFIVFSF | 181 | P25105 | |
| VISTPGVVARFVEFL | 121 | P52294 | |
| VAIVFVICFLPSVVV | 236 | P49019 | |
| LVIDVTFPSVAPFEL | 31 | Q9BSH3 | |
| AIVTAFITFIPKFIE | 446 | Q9H2Y9 | |
| VPFLIVGSVFVAFII | 116 | Q6UWI4 | |
| IFPVLVLLTVFIFVV | 586 | G3V0H7 | |
| VPAFLVELVSLVFLI | 56 | A6NNN8 | |
| IFSIPIQIFTIATVL | 201 | A6NMS3 | |
| EETVFLPLIVGFISI | 251 | Q9Y4F9 | |
| IVSAFVGFSVIPQEL | 276 | Q6PIS1 | |
| LPEEIFFTISIVGVL | 26 | Q01718 | |
| IVITGFEVTVILFFI | 46 | Q9UBR5 | |
| VIIVAAITAVIAFPN | 431 | P51790 | |
| EVTAATVVLLFFPIV | 101 | Q9UKR8 | |
| TVVLLFFPIVGDVAL | 106 | Q9UKR8 | |
| FPISVAVFALITLQV | 6 | O95498 | |
| FTAAEIAPFVEILLT | 541 | P55060 | |
| LSFAQLVSFTIFVPI | 936 | O75762 | |
| TIETVFPFDVAVKFV | 881 | Q7Z392 | |
| LAFLFSFVVVVPLSE | 16 | Q6ZVK1 | |
| VPGLLLVFVTSAFTV | 621 | Q96PX8 | |
| VIITTVSVLVFDFRP | 341 | Q9BS91 | |
| VVSAFIFLFIKSEIP | 136 | Q7Z5S9 | |
| VPVTLLAIAVILAFV | 646 | Q9H2E6 | |
| PIIVSIRSKVAFQFI | 361 | O95759 | |
| FLLFVVVVSIVTFRP | 531 | Q01959 | |
| LTFSPLTVVIFVVIC | 216 | Q8TCT8 | |
| VLPIIVFFSCVISVL | 266 | O00337 | |
| SVFLVIVPLFTDTIN | 436 | Q92536 | |
| FNLFAIVPFIVSLIS | 186 | Q9NYW2 | |
| IVAVILTVPVLFFTV | 361 | Q9H2H9 | |
| VGVAAVVLVPIFAAF | 766 | Q13488 |