Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 BACH2 ZNF780B ZNF316 SALL4 RELB ZNF275 ZSCAN25 ZNF236 ZNF467 ZNF496 ZNF623 SCX ZNF774 ZNF512B ZNF630 SALL1 MZF1 ZNF425 ZBED6 NR2E1 ZNF286B NFXL1 ZNF814 ZNF74 PAX2 PAX5 NOTCH1 ZNF646	7.64e-08	1412	185	35	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 BACH2 ZNF780B ZNF316 SALL4 RELB ZNF275 ZSCAN25 ZNF236 ZNF467 ZNF496 ZNF623 SCX ZNF774 ZNF512B ZNF630 SALL1 MZF1 ZNF425 NR2E1 ZNF286B NFXL1 ZNF814 ZNF74 PAX2 PAX5 ZNF646	1.50e-06	1459	185	33	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF134 ZNF311 ZNF211 ZBTB17 ZNF157 ZNF473 BACH2 ZNF780B ZNF316 SALL4 RELB ZNF275 ZSCAN25 ZNF236 ZNF467 ZNF496 ZNF623 SCX ZNF774 ZNF630 SALL1 MZF1 NR2E1 ZNF286B ZNF814 ZNF74 PAX2 PAX5 NOTCH1 ZNF646	2.07e-06	1271	185	30	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF134 ZNF311 ZNF211 ZBTB17 ZNF157 ZNF473 BACH2 ZNF780B ZNF316 SALL4 RELB ZNF275 ZSCAN25 ZNF236 ZNF467 ZNF496 ZNF623 SCX ZNF774 ZNF630 SALL1 MZF1 NR2E1 ZNF286B ZNF814 ZNF74 PAX2 PAX5 ZNF646	3.99e-06	1244	185	29	GO:0000978
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FRAS1 LAMA2 LAMA3 PAPLN TECTA SSPOP ZP1 SBSPON FBN3	6.65e-05	188	185	9	GO:0005201
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR PPIL2 TRIM50	1.90e-04	372	185	12	GO:0061630
GeneOntologyMolecularFunction	protein tyrosine kinase activator activity	ERBB3 DGKQ TGFA ALK	3.33e-04	36	185	4	GO:0030296
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR PPIL2 TRIM50	3.52e-04	398	185	12	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR PPIL2 TRIM50 LNX1	4.85e-04	473	185	13	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR PPIL2 TRIM50 LNX1	1.01e-03	512	185	13	GO:0019787
GeneOntologyCellularComponent	extracellular matrix	FRAS1 ADAMTS2 LAMA2 LAMA3 PAPLN MUC5B CPZ TECTA SSPOP ZP1 CCN4 EYS P3H2 GLG1 SBSPON ADAMTS18 LTBP3 FBN3	1.80e-05	656	182	18	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	FRAS1 ADAMTS2 LAMA2 LAMA3 PAPLN MUC5B CPZ TECTA SSPOP ZP1 CCN4 EYS P3H2 GLG1 SBSPON ADAMTS18 LTBP3 FBN3	1.88e-05	658	182	18	GO:0030312
MousePheno	increased macrophage cell number	RAG1 BACH2 RELB ZNF467 P2RX7 SQSTM1 PRKDC PAX5 FBLIM1 NOTCH3	4.58e-06	162	138	10	MP:0005425
MousePheno	abnormal appendicular skeleton morphology	PDS5B FRAS1 TRAF6 ADAMTS2 SYT17 BACH2 SALL4 ANKRD20A3P ANKRD20A8P TUBGCP2 IDS SSPOP SCX BMPR1B SALL1 ANKRD20A4P P2RX7 SACS GLG1 NFXL1 LTBP3 FBLIM1 ALK ANKRD20A1	6.71e-06	896	138	24	MP:0009250
MousePheno	abnormal pectoral girdle bone morphology	PDS5B FRAS1 ADAMTS2 ANKRD20A3P ANKRD20A8P TUBGCP2 IDS SSPOP BMPR1B ANKRD20A4P SACS ANKRD20A1	4.33e-05	301	138	12	MP:0004508
MousePheno	abnormal sternum morphology	PDS5B FRAS1 ADAMTS2 ANKRD20A3P ANKRD20A8P TUBGCP2 SSPOP BMPR1B ANKRD20A4P SACS ANKRD20A1	4.48e-05	255	138	11	MP:0000157
MousePheno	abnormal immunoglobulin heavy chain V(D)J recombination	RAG1 PRKDC PAX5	5.08e-05	8	138	3	MP:0008760
MousePheno	middle ear effusion	SALL4 MUC5B IDS	7.57e-05	9	138	3	MP:0030410
MousePheno	absent triquetrum	SALL4 SALL1	9.68e-05	2	138	2	MP:0030862
MousePheno	absent late pro-B cells	RAG1 PAX5	9.68e-05	2	138	2	MP:0005434
MousePheno	abnormal macrophage cell number	RAG1 BACH2 LAMA3 RELB ZNF467 P2RX7 SQSTM1 PRKDC PAX5 FBLIM1 NOTCH3	9.74e-05	278	138	11	MP:0020202
MousePheno	absent mature B cells	RAG1 PRKDC PAX5	1.47e-04	11	138	3	MP:0008212
Domain	ZnF_C2H2	ZXDC RAG1 ZNF134 ZNF311 ZNF672 ZNF211 RNF166 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF512B ZNF462 ZNF630 SALL1 RNF125 MZF1 ZNF425 HELZ2 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	1.10e-13	808	184	35	SM00355
Domain	Znf_C2H2-like	ZXDC RAG1 ZNF134 ZNF311 ZNF672 ZNF211 RNF166 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF512B ZNF462 ZNF630 SALL1 RNF125 MZF1 ZNF425 HELZ2 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	3.87e-13	796	184	34	IPR015880
Domain	Znf_C2H2	ZXDC ZNF134 ZNF311 ZNF672 ZNF211 RNF166 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF512B ZNF462 ZNF630 SALL1 RNF125 MZF1 ZNF425 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	2.77e-12	805	184	33	IPR007087
Domain	-	ZXDC RAG1 ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF462 ZNF630 SALL1 MZF1 ZNF425 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	4.85e-12	679	184	30	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZXDC ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF512B ZNF462 ZNF630 SALL1 MZF1 ZNF425 HELZ2 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	5.15e-12	775	184	32	PS50157
Domain	ZINC_FINGER_C2H2_1	ZXDC ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF512B ZNF462 ZNF630 SALL1 MZF1 ZNF425 HELZ2 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	5.52e-12	777	184	32	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZXDC RAG1 ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF462 ZNF630 SALL1 MZF1 ZNF425 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	8.37e-12	694	184	30	IPR013087
Domain	zf-C2H2	ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF462 ZNF630 SALL1 MZF1 ZNF425 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	4.24e-11	693	184	29	PF00096
Domain	EGF-like_dom	SELE MASP1 FRAS1 LAMA2 LAMA3 TECTA VWCE TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	1.83e-07	249	184	14	IPR000742
Domain	TSP_1	ADAMTS2 ADGRB3 PAPLN SSPOP CCN4 SBSPON ADAMTS18 UNC5D	1.86e-07	63	184	8	PF00090
Domain	TSP1	ADAMTS2 ADGRB3 PAPLN SSPOP CCN4 SBSPON ADAMTS18 UNC5D	2.38e-07	65	184	8	SM00209
Domain	TSP1_rpt	ADAMTS2 ADGRB3 PAPLN SSPOP CCN4 SBSPON ADAMTS18 UNC5D	2.38e-07	65	184	8	IPR000884
Domain	TSP1	ADAMTS2 ADGRB3 PAPLN SSPOP CCN4 SBSPON ADAMTS18 UNC5D	2.38e-07	65	184	8	PS50092
Domain	Growth_fac_rcpt_	FRAS1 ERBB3 LAMA3 VWCE CCN4 EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	4.24e-07	156	184	11	IPR009030
Domain	EGF	SELE FRAS1 LAMA2 LAMA3 TECTA VWCE TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	6.14e-07	235	184	13	SM00181
Domain	VWC_out	FRAS1 MUC5B TECTA VWCE SSPOP	9.14e-07	19	184	5	SM00215
Domain	EGF_1	SELE MASP1 LAMA2 LAMA3 VWCE SSPOP TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	1.54e-06	255	184	13	PS00022
Domain	VWFC_2	FRAS1 MUC5B TECTA VWCE SSPOP CCN4	1.79e-06	38	184	6	PS50184
Domain	VWC	FRAS1 MUC5B TECTA VWCE SSPOP CCN4	1.79e-06	38	184	6	SM00214
Domain	EGF_2	SELE MASP1 LAMA2 LAMA3 VWCE SSPOP TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	2.35e-06	265	184	13	PS01186
Domain	VWF_dom	FRAS1 MUC5B TECTA VWCE SSPOP CCN4	3.29e-06	42	184	6	IPR001007
Domain	Znf_RING	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR NFXL1 UNKL TRIM50 LNX1	4.51e-06	326	184	14	IPR001841
Domain	Znf_RING_CS	RAG1 RC3H2 TRAF6 RNF166 TRIM4 RNF125 TRIM9 CHFR TRIM50 LNX1	5.05e-06	163	184	10	IPR017907
Domain	EGF_Ca-bd_CS	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	5.22e-06	97	184	8	IPR018097
Domain	EGF_CA	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	6.08e-06	99	184	8	PS01187
Domain	ZF_RING_1	RAG1 RC3H2 TRAF6 RNF166 TRIM4 RNF125 TRIM9 TRIM28 CHFR NFXL1 UNKL TRIM50 LNX1	6.54e-06	291	184	13	PS00518
Domain	ASX_HYDROXYL	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	6.55e-06	100	184	8	PS00010
Domain	hEGF	EYS LTBP3 FBN3 NOTCH1 NOTCH3	7.19e-06	28	184	5	PF12661
Domain	ZF_RING_2	RAG1 RC3H2 TRAF6 RNF166 TRIM4 RNF125 TRIM9 TRIM28 CHFR NFXL1 UNKL TRIM50 LNX1	8.45e-06	298	184	13	PS50089
Domain	TIL_dom	MUC5B TECTA SSPOP LRP2	8.45e-06	14	184	4	IPR002919
Domain	-	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 MLLT10 RUFY2 RNF125 TRIM9 TRIM28 CHFR MLLT6 PPIL2 TRIM50 LNX1	9.99e-06	449	184	16	3.30.40.10
Domain	EGF-type_Asp/Asn_hydroxyl_site	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	1.01e-05	106	184	8	IPR000152
Domain	EGF-like_CS	SELE MASP1 LAMA2 LAMA3 VWCE TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	1.12e-05	261	184	12	IPR013032
Domain	KRAB	ZNF311 ZNF211 ZNF157 ZNF473 ZNF780B ZNF316 ZNF275 ZNF235 ZNF496 ZNF774 ZNF630 ZNF425 ZNF814 ZNF74	1.31e-05	358	184	14	PS50805
Domain	Znf_RING/FYVE/PHD	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 MLLT10 RUFY2 RNF125 TRIM9 TRIM28 CHFR MLLT6 PPIL2 TRIM50 LNX1	1.31e-05	459	184	16	IPR013083
Domain	zf-C3HC4	RAG1 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR TRIM50 LNX1	1.36e-05	223	184	11	PF00097
Domain	KRAB	ZNF311 ZNF211 ZNF157 ZNF473 ZNF780B ZNF316 ZNF275 ZSCAN25 ZNF235 ZNF496 ZNF630 ZNF425 ZNF814 ZNF74	1.83e-05	369	184	14	SM00349
Domain	KRAB	ZNF311 ZNF211 ZNF157 ZNF473 ZNF780B ZNF316 ZNF275 ZSCAN25 ZNF235 ZNF496 ZNF630 ZNF425 ZNF814 ZNF74	1.89e-05	370	184	14	IPR001909
Domain	EGF_3	SELE MASP1 VWCE SSPOP TGFA EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	2.22e-05	235	184	11	PS50026
Domain	EGF_CA	MASP1 VWCE LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	2.24e-05	86	184	7	PF07645
Domain	VWFC_1	FRAS1 MUC5B VWCE SSPOP CCN4	2.59e-05	36	184	5	PS01208
Domain	EGF_CA	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	2.82e-05	122	184	8	SM00179
Domain	EGF-like_Ca-bd_dom	MASP1 VWCE EYS LRP2 LTBP3 FBN3 NOTCH1 NOTCH3	3.17e-05	124	184	8	IPR001881
Domain	EGF	SELE TECTA TGFA EYS LRP2 FBN3 NOTCH1 NOTCH3	3.56e-05	126	184	8	PF00008
Domain	RING	RAG1 RC3H2 TRAF6 RNF166 TRIM4 RNF125 TRIM9 TRIM28 CHFR UNKL TRIM50 LNX1	5.19e-05	305	184	12	SM00184
Domain	Znf_C3HC4_RING-type	RAG1 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM50 LNX1	5.32e-05	172	184	9	IPR018957
Domain	KRAB	ZNF311 ZNF211 ZNF157 ZNF473 ZNF780B ZNF316 ZNF275 ZNF235 ZNF496 ZNF630 ZNF425 ZNF814 ZNF74	5.75e-05	358	184	13	PF01352
Domain	zf-C2H2_6	ZNF311 ZNF672 ZNF211 ZNF157 ZNF473 ZNF780B ZNF316 ZNF236 ZNF467 ZNF425 ZNF814 ZNF646	6.85e-05	314	184	12	PF13912
Domain	VWC	FRAS1 MUC5B VWCE CCN4	1.55e-04	28	184	4	PF00093
Domain	C8	MUC5B TECTA SSPOP	1.94e-04	12	184	3	PF08742
Domain	TIL	MUC5B TECTA SSPOP	1.94e-04	12	184	3	PF01826
Domain	LRR_6	NLRP2 FBXL7 LRRC14 NLRP4 NLRC3	2.05e-04	55	184	5	PF13516
Domain	Unchr_dom_Cys-rich	MUC5B TECTA SSPOP	2.50e-04	13	184	3	IPR014853
Domain	C8	MUC5B TECTA SSPOP	2.50e-04	13	184	3	SM00832
Domain	Pax2_C	PAX2 PAX5	2.88e-04	3	184	2	IPR022130
Domain	DUF3454	NOTCH1 NOTCH3	2.88e-04	3	184	2	PF11936
Domain	Pax2_C	PAX2 PAX5	2.88e-04	3	184	2	PF12403
Domain	DUF3454_notch	NOTCH1 NOTCH3	2.88e-04	3	184	2	IPR024600
Domain	DUF3454	NOTCH1 NOTCH3	2.88e-04	3	184	2	SM01334
Domain	VWF_type-D	MUC5B TECTA SSPOP	4.79e-04	16	184	3	IPR001846
Domain	VWFD	MUC5B TECTA SSPOP	4.79e-04	16	184	3	PS51233
Domain	VWD	MUC5B TECTA SSPOP	4.79e-04	16	184	3	SM00216
Domain	VWD	MUC5B TECTA SSPOP	4.79e-04	16	184	3	PF00094
Domain	Notch	NOTCH1 NOTCH3	5.72e-04	4	184	2	IPR008297
Domain	NODP	NOTCH1 NOTCH3	5.72e-04	4	184	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH3	5.72e-04	4	184	2	IPR011656
Domain	RNase_II/R_CS	DIS3 HELZ2	5.72e-04	4	184	2	IPR022966
Domain	ZF_C2HC_RNF	RNF166 RNF125	5.72e-04	4	184	2	PS51803
Domain	Notch_NOD_dom	NOTCH1 NOTCH3	5.72e-04	4	184	2	IPR010660
Domain	NOD	NOTCH1 NOTCH3	5.72e-04	4	184	2	PF06816
Domain	NOD	NOTCH1 NOTCH3	5.72e-04	4	184	2	SM01338
Domain	NODP	NOTCH1 NOTCH3	5.72e-04	4	184	2	SM01339
Domain	CTCK_1	MUC5B SSPOP CCN4	6.88e-04	18	184	3	PS01185
Domain	PLAC	ADAMTS2 PAPLN ADAMTS18	8.11e-04	19	184	3	PS50900
Domain	PLAC	ADAMTS2 PAPLN ADAMTS18	8.11e-04	19	184	3	IPR010909
Domain	Laminin_domII	LAMA2 LAMA3	9.47e-04	5	184	2	IPR010307
Domain	Laminin_aI	LAMA2 LAMA3	9.47e-04	5	184	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA3	9.47e-04	5	184	2	PF06008
Domain	Laminin_II	LAMA2 LAMA3	9.47e-04	5	184	2	PF06009
Domain	LNR	NOTCH1 NOTCH3	9.47e-04	5	184	2	PS50258
Domain	-	TMPRSS13 SSPOP LRP2 ALK	1.08e-03	46	184	4	4.10.400.10
Domain	LDLRA_1	TMPRSS13 SSPOP LRP2 ALK	1.26e-03	48	184	4	PS01209
Domain	LDrepeatLR_classA_rpt	TMPRSS13 SSPOP LRP2 ALK	1.37e-03	49	184	4	IPR002172
Domain	LDLa	TMPRSS13 SSPOP LRP2 ALK	1.37e-03	49	184	4	SM00192
Domain	LDLRA_2	TMPRSS13 SSPOP LRP2 ALK	1.37e-03	49	184	4	PS50068
Domain	NACHT	NLRP2 NLRP4 NLRC3	1.44e-03	23	184	3	PS50837
Domain	NACHT_NTPase	NLRP2 NLRP4 NLRC3	1.44e-03	23	184	3	IPR007111
Domain	ADAM_spacer1	ADAMTS2 PAPLN ADAMTS18	1.44e-03	23	184	3	IPR010294
Domain	ADAM_spacer1	ADAMTS2 PAPLN ADAMTS18	1.44e-03	23	184	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS2 PAPLN ADAMTS18	1.63e-03	24	184	3	IPR013273
Domain	Cys_knot_C	MUC5B SSPOP CCN4	1.84e-03	25	184	3	IPR006207
Domain	CTCK_2	MUC5B SSPOP CCN4	1.84e-03	25	184	3	PS01225
Domain	TB	LTBP3 FBN3	1.96e-03	7	184	2	PF00683
Domain	Notch_dom	NOTCH1 NOTCH3	1.96e-03	7	184	2	IPR000800
Domain	zf-Di19	RNF166 RNF125	1.96e-03	7	184	2	PF05605
Domain	Di19_Zn_binding_dom	RNF166 RNF125	1.96e-03	7	184	2	IPR008598
Domain	Notch	NOTCH1 NOTCH3	1.96e-03	7	184	2	PF00066
Domain	NL	NOTCH1 NOTCH3	1.96e-03	7	184	2	SM00004
Domain	cEGF	LRP2 LTBP3 FBN3	2.07e-03	26	184	3	PF12662
Domain	cEGF	LRP2 LTBP3 FBN3	2.07e-03	26	184	3	IPR026823
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS2 MUC5B SSPOP SBSPON ADAMTS18 NOTCH1 NOTCH3	3.41e-06	68	133	7	M27303
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZXDC FLNC FRAS1 ARHGEF19 MYO7A ZNF316 DGKQ PAPLN RELB MLLT10 ZNF236 STK11IP EML3 TLNRD1 TRIM28 DEF6 HELZ2 UNKL MLLT6 PAX2 LRRC14 LTBP3 PRKDC MCF2L PREX1 NOTCH1	3.40e-10	1105	188	26	35748872
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZXDC PDS5B ZBTB17 ZNF473 BACH2 SALL4 MLLT10 ZNF235 ZNF236 ZNF496 ZNF623 ZNF462 SALL1 TRIM28 NR2E1 ZNF286B MLLT6 PAX2 FBLIM1 MBNL3 DOP1B ZNF646	6.07e-10	808	188	22	20412781
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	5.69e-08	8	188	4	12634303
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	ZNF211 LAMA2 SSPOP ZDHHC15 NFXL1 LRP2 LTBP3	1.20e-07	71	188	7	33541421
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZXDC KLHL40 BACH2 RELB ZNF275 MLLT10 ZNF235 ZNF467 CHAMP1 ZNF462 TRIM9 TRIM28 SQSTM1 NR2E1 PAX2 PAX5 FBLIM1	3.61e-07	709	188	17	22988430
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FRAS1 LAMA2 LAMA3 GRIP1 PAX2	4.68e-07	29	188	5	22613833
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB3 CR1 LRP2 SNX27 ALK NOTCH1 NOTCH3	1.35e-06	101	188	7	23382219
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	FRAS1 TRPC4 LAMA3 GRIP1	1.43e-06	16	188	4	16880404
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	RC3H2 TRAF6 RNF166 TRIM4 RNF125 TRIM9 CHFR	1.76e-06	105	188	7	22493164
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	SELE LAMA2 LAMA3	3.07e-06	6	188	3	9597096
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS2 ADGRB3 PAPLN SSPOP CCN4 ADAMTS18	3.40e-06	75	188	6	20637190
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	PDS5B DHX40 CHAMP1 ZNF512B ZNF462 SALL1 RECQL5 PPIL2 KIF2A	3.71e-06	222	188	9	37071664
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ADGRB3 PUM2 DIS3 ZNF462 FBXL7 TRIM9 HELZ2 PREX1 DOP1B	4.14e-06	225	188	9	12168954
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	USP53 KLHL24 RELB MLLT10 SYNGAP1 PLEKHG4B SALL1 SQSTM1 PIP4P1 SYT14 MLLT6 NOTCH1	4.40e-06	430	188	12	35044719
Pubmed	Continued expression of GATA3 is necessary for cochlear neurosensory development.	MYO7A TECTA PAX2 NOTCH1	8.07e-06	24	188	4	23614009
Pubmed	The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.	MYO7A TECTA NOTCH1	8.53e-06	8	188	3	16141228
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ADAMTS2 POLA1 BACH2 TRPC4 MARCHF2 ZNF316 LAMA2 SALL4 IDS CHAMP1 EML3 SYNGAP1 TGFA TLNRD1 TRANK1 ANXA2R FBLIM1 UNC5D FBN3 NOTCH1	1.06e-05	1215	188	20	15146197
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYO7A POLA1 ZNF316 ANKRD20A3P CHN1 SSPOP CCN4 FBXL7 TRIM9 PLXNA4 PKHD1 LRP2 PRKDC FBN3 DOP1B	1.26e-05	736	188	15	29676528
Pubmed	Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.	MYO7A PAX2 NOTCH1	1.27e-05	9	188	3	20727173
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	SALL4 TLNRD1 BMPR1B SALL1 RNF125 PAX2 PAX5 FBLIM1 NLRP4 NOTCH1 NOTCH3	2.18e-05	424	188	11	21731673
Pubmed	Control of Tissue-Resident Invariant NKT Cells by Vitamin A Metabolites and P2X7-Mediated Cell Death.	RAG1 P2RX7	2.91e-05	2	188	2	31308092
Pubmed	Defensins: key players or bystanders in infection, injury, and repair in the lung?	DEFB118 DEFB127	2.91e-05	2	188	2	10588992
Pubmed	Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.	SALL4 SALL1	2.91e-05	2	188	2	19476507
Pubmed	Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.	SHC3 ALK	2.91e-05	2	188	2	12185581
Pubmed	During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.	RAG1 PRKDC	2.91e-05	2	188	2	12498815
Pubmed	Expression analysis of a Notch homologue in the mouse embryo.	ASS1 NOTCH1	2.91e-05	2	188	2	1426644
Pubmed	A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.	NOTCH1 NOTCH3	2.91e-05	2	188	2	21191019
Pubmed	Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.	PAX5 NOTCH1	2.91e-05	2	188	2	15356142
Pubmed	Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.	NOTCH1 NOTCH3	2.91e-05	2	188	2	21768299
Pubmed	Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.	NOTCH1 NOTCH3	2.91e-05	2	188	2	25700162
Pubmed	Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.	NOTCH1 NOTCH3	2.91e-05	2	188	2	18069660
Pubmed	Macromolecular organization of basement membranes.	LAMA2 LAMA3	2.91e-05	2	188	2	8939648
Pubmed	Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.	NOTCH1 NOTCH3	2.91e-05	2	188	2	34878922
Pubmed	Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors.	RAG1 PAX5	2.91e-05	2	188	2	15557148
Pubmed	DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer.	MZF1 PAX2	2.91e-05	2	188	2	27764784
Pubmed	TRAF6 is a critical factor for dendritic cell maturation and development.	TRAF6 RELB	2.91e-05	2	188	2	14499111
Pubmed	Identification of two promoters for human D-amino acid oxidase gene: implication for the differential promoter regulation mediated by PAX5/PAX2.	PAX2 PAX5	2.91e-05	2	188	2	25500505
Pubmed	Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1.	CCN4 NOTCH1	2.91e-05	2	188	2	21516124
Pubmed	Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.	FRAS1 GRIP1	2.91e-05	2	188	2	18155042
Pubmed	Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.	SALL4 SALL1	2.91e-05	2	188	2	19350679
Pubmed	Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk.	NOTCH1 NOTCH3	2.91e-05	2	188	2	17881497
Pubmed	The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.	NOTCH1 NOTCH3	2.91e-05	2	188	2	29023469
Pubmed	Novel role of the Ras cascade in memory B cell response.	RAG1 PRKDC	2.91e-05	2	188	2	16111632
Pubmed	Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.	NOTCH1 NOTCH3	2.91e-05	2	188	2	24728738
Pubmed	Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6.	TRAF6 SQSTM1	2.91e-05	2	188	2	27681126
Pubmed	The transcription factor BACH2 promotes tumor immunosuppression.	RAG1 BACH2	2.91e-05	2	188	2	26731475
Pubmed	Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.	NOTCH1 NOTCH3	2.91e-05	2	188	2	14595837
Pubmed	Effect of different Ig transgenes on B cell differentiation in scid mice.	RAG1 PRKDC	2.91e-05	2	188	2	9088976
Pubmed	NLRC3 alleviates hypoxia/reoxygenation induced inflammation in RAW264.7 cells by inhibiting K63-linked ubiquitination of TRAF6.	TRAF6 NLRC3	2.91e-05	2	188	2	32386989
Pubmed	Mouse homolog of SALL1, a causative gene for Townes-Brocks syndrome, binds to A/T-rich sequences in pericentric heterochromatin via its C-terminal zinc finger domains.	SALL4 SALL1	2.91e-05	2	188	2	17295837
Pubmed	Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis.	CCN4 NOTCH1	2.91e-05	2	188	2	27813493
Pubmed	Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors.	NOTCH1 NOTCH3	2.91e-05	2	188	2	16507912
Pubmed	Cardiac apoptosis in severe relapsing fever borreliosis.	RAG1 PRKDC	2.91e-05	2	188	2	16239571
Pubmed	Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice.	RAG1 PRKDC	2.91e-05	2	188	2	18752298
Pubmed	RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy.	RNF166 SQSTM1	2.91e-05	2	188	2	27880896
Pubmed	Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.	TRIM28 ZNF74	2.91e-05	2	188	2	17298944
Pubmed	Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy.	TRAF6 SQSTM1	2.91e-05	2	188	2	27458013
Pubmed	Purinergic P2X7 receptor drives T cell lineage choice and shapes peripheral γδ cells.	RAG1 P2RX7	2.91e-05	2	188	2	22649196
Pubmed	Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.	NOTCH1 NOTCH3	2.91e-05	2	188	2	33021719
Pubmed	Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1.	SELE GLG1	2.91e-05	2	188	2	11404363
Pubmed	TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells.	RAG1 TRIM28	2.91e-05	2	188	2	23169648
Pubmed	TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis.	RAG1 TRAF6	2.91e-05	2	188	2	16921377
Pubmed	An intrinsic BM hematopoietic niche occupancy defect of HSC in scid mice facilitates exogenous HSC engraftment.	RAG1 PRKDC	2.91e-05	2	188	2	22147896
Pubmed	Diagnostic utility of PAX2 and PAX5 in distinguishing non-small cell lung cancer from small cell lung cancer.	PAX2 PAX5	2.91e-05	2	188	2	26823795
Pubmed	Development of functional B cells in a line of SCID mice with transgenes coding for anti-double-stranded DNA antibody.	RAG1 PRKDC	2.91e-05	2	188	2	16393973
Pubmed	Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family.	SALL4 SALL1	2.91e-05	2	188	2	12395297
Pubmed	The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance.	NOTCH1 NOTCH3	2.91e-05	2	188	2	26634853
Pubmed	Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.	PKHD1 PRKDC	2.91e-05	2	188	2	24984783
Pubmed	Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.	PAX2 PAX5	2.91e-05	2	188	2	10662641
Pubmed	The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity.	RAG1 NLRC3	2.91e-05	2	188	2	30566882
Pubmed	Transient Notch signaling induces NK cell potential in Pax5-deficient pro-B cells.	PAX5 NOTCH1	2.91e-05	2	188	2	17111353
Pubmed	Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.	NOTCH1 NOTCH3	2.91e-05	2	188	2	26563570
Pubmed	The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination.	RAG1 PRKDC	2.91e-05	2	188	2	17296939
Pubmed	Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions.	RAG1 PRKDC	2.91e-05	2	188	2	14662857
Pubmed	Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo.	RAG1 PRKDC	2.91e-05	2	188	2	9278319
Pubmed	Cell-fate transition and determination analysis of mouse male germ cells throughout development.	ZXDC NOTCH1 NOTCH3	5.42e-05	14	188	3	34824237
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	RAG1 RCAN1 NLRP2 P2RX7 PRKDC NLRP4 ALK	5.72e-05	179	188	7	19074885
Pubmed	COUP-TFI controls Notch regulation of hair cell and support cell differentiation.	MYO7A NOTCH1 NOTCH3	6.74e-05	15	188	3	16914494
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ERBB3 TRAF6 ZNF473 RCAN1 ADGRB3 IDS SYNGAP1 RUFY2 ZNF512B PPT1 SACS TRIM9 LRP2 LTBP3 PRKDC SGSM3 LNX1 PREX1 DOP1B	7.53e-05	1285	188	19	35914814
Pubmed	Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice.	RAG1 PRKDC	8.69e-05	3	188	2	26168294
Pubmed	Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.	NOTCH1 NOTCH3	8.69e-05	3	188	2	15987768
Pubmed	Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex.	SALL4 SALL1	8.69e-05	3	188	2	19440552
Pubmed	Notch receptor expression in human brain arteriovenous malformations.	NOTCH1 NOTCH3	8.69e-05	3	188	2	25846406
Pubmed	Dense granule protein 3 of Toxoplasma gondii plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8+ T cells during the chronic stage of infection.	RAG1 PRKDC	8.69e-05	3	188	2	37868957
Pubmed	Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.	NOTCH1 NOTCH3	8.69e-05	3	188	2	27697639
Pubmed	NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.	NOTCH1 NOTCH3	8.69e-05	3	188	2	20801121
Pubmed	T cell requirement for development of chronic ulcerative dermatitis in E- and P-selectin-deficient mice.	SELE RAG1	8.69e-05	3	188	2	12391189
Pubmed	Resistance to skin tumorigenesis in DNAPK-deficient SCID mice is not due to immunodeficiency but results from hypersensitivity to TPA-induced apoptosis.	RAG1 PRKDC	8.69e-05	3	188	2	10545405
Pubmed	Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons.	RAG1 PRKDC	8.69e-05	3	188	2	11452126
Pubmed	Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESCAPE study.	SALL1 PAX2	8.69e-05	3	188	2	16971658
Pubmed	A xenograft model of macrophage activation syndrome amenable to anti-CD33 and anti-IL-6R treatment.	RAG1 PRKDC	8.69e-05	3	188	2	27699249
Pubmed	A Hitchhiker's guide to humanized mice: new pathways to studying viral infections.	RAG1 PRKDC	8.69e-05	3	188	2	29446074
Pubmed	Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.	RAG1 CCN4	8.69e-05	3	188	2	28783045
Pubmed	Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.	PAX5 NOTCH1	8.69e-05	3	188	2	12479824
Pubmed	DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1.	TRAF6 SQSTM1	8.69e-05	3	188	2	30281815
Pubmed	Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.	NOTCH1 NOTCH3	8.69e-05	3	188	2	7615640
Pubmed	The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.	NOTCH1 NOTCH3	8.69e-05	3	188	2	7918097
Pubmed	Smooth muscle Notch1 mediates neointimal formation after vascular injury.	NOTCH1 NOTCH3	8.69e-05	3	188	2	19433762
Pubmed	Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.	NOTCH1 NOTCH3	8.69e-05	3	188	2	18483410
Pubmed	KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.	NOTCH1 NOTCH3	8.69e-05	3	188	2	34854382
Interaction	ZNF74 interactions	VWCE TRIM28 P3H2 ZNF74 NOTCH1 NOTCH3	5.62e-07	34	183	6	int:ZNF74
Interaction	ZNF211 interactions	ZNF211 ZNF316 ZNF467 ZDHHC15 TRIM28	1.06e-06	21	183	5	int:ZNF211
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.44e-05	6	183	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.51e-05	7	183	3	int:ANKRD20A2P
Interaction	UBE2E2 interactions	RC3H2 RNF166 RNF125 TRIM28 SQSTM1 CHFR TRIM50	2.74e-05	96	183	7	int:UBE2E2
Cytoband	7q36.1	AOC1 ZNF467 SSPOP ZNF425	2.51e-04	74	188	4	7q36.1
Cytoband	19q13.4	ZNF134 ZNF211 MZF1 TRIM28	3.22e-04	79	188	4	19q13.4
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZXDC ZNF134 ZNF311 ZNF672 ZNF211 ZBTB17 ZNF157 ZNF473 ZNF780B ZNF316 SALL4 ZNF275 ZSCAN25 ZNF235 ZNF236 ZNF467 CHAMP1 ZNF496 ZNF623 ZNF774 ZNF462 ZNF630 SALL1 MZF1 ZNF425 ZNF286B ZNF814 ZNF74 ZNF488 ZNF646	5.82e-14	718	144	30	28
GeneFamily	Ring finger proteins	RAG1 RC3H2 TRAF6 RNF166 TRIM4 MARCHF2 RNF125 TRIM9 TRIM28 CHFR TRIM50 LNX1	2.11e-06	275	144	12	58
GeneFamily	Ankyrin repeat domain containing	TRPC4 ANKRD20A2P ANKRD20A3P TRANK1 ANKRD20A4P NOTCH1 ANKRD20A1 NOTCH3	7.24e-04	242	144	8	403
GeneFamily	NLR family	NLRP2 NLRP4 NLRC3	1.00e-03	25	144	3	666
GeneFamily	Paired boxes	PAX2 PAX5	2.19e-03	9	144	2	675
GeneFamily	Zinc fingers CCCH-type	RC3H2 UNKL MBNL3	2.69e-03	35	144	3	73
GeneFamily	Laminin subunits	LAMA2 LAMA3	3.95e-03	12	144	2	626
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL24 ZBTB17 KLHL40 BACH2 KLHL38	4.39e-03	134	144	5	861
GeneFamily	Kelch like\|BTB domain containing	KLHL24 KLHL40 KLHL38	4.53e-03	42	144	3	617
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF2B STARD9 KIF2A	5.85e-03	46	144	3	622
GeneFamily	Defensins, beta	DEFB118 DEFB127 DEFB108A	6.21e-03	47	144	3	503
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM4 TRIM9 TRIM28 TRIM50	7.02e-03	95	144	4	59
GeneFamily	DEAH-box helicases	DHX37 DHX40	7.03e-03	16	144	2	500
GeneFamily	PDZ domain containing	FRMPD2 GRIP1 SNX27 LNX1 PREX1	7.43e-03	152	144	5	1220
GeneFamily	Synaptotagmins	SYT17 SYT14	7.92e-03	17	144	2	765
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 LAMA2 LAMA3 PAPLN TECTA VWCE SSPOP ZP1 CCN4 EYS SBSPON LTBP3 FBN3	1.76e-09	196	187	13	M3008
Coexpression	NABA_CORE_MATRISOME	FRAS1 LAMA2 LAMA3 PAPLN TECTA VWCE SSPOP ZP1 CCN4 EYS SBSPON LTBP3 FBN3	9.94e-08	275	187	13	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 LAMA2 LAMA3 PAPLN TECTA VWCE SSPOP ZP1 CCN4 SBSPON LTBP3	1.37e-07	191	187	11	MM17059
Coexpression	NABA_CORE_MATRISOME	FRAS1 LAMA2 LAMA3 PAPLN TECTA VWCE SSPOP ZP1 CCN4 SBSPON LTBP3	4.15e-06	270	187	11	MM17057
Coexpression	GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN	MACROD1 ZNF623 TGFA QSOX1 ZDHHC15 RNF125 P2RX7 KIF2A PREX1	1.44e-05	200	187	9	M7157
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	TRPC4 ADGRB3 LAMA2 CCN4 FBXL7 TRIM9 STARD9 FBLIM1 NOTCH3	7.38e-08	179	188	9	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SALL4 MUC5B SSPOP TRANK1 PKHD1 LRP2 ZNF488 UNC5D	9.34e-08	184	188	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SALL4 MUC5B SSPOP TRANK1 PKHD1 LRP2 ZNF488 UNC5D	9.34e-08	184	188	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SALL4 MUC5B SSPOP TRANK1 PKHD1 LRP2 ZNF488 UNC5D	9.34e-08	184	188	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 BACH2 ITGA9 GRIP1 ZNF462 FBXL7 P3H2 ADAMTS18 PAX2	1.12e-07	188	188	9	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SALL1 P3H2 HPN CFAP221 PLXNA4 PKHD1 PAX2 MCF2L	1.23e-07	190	188	9	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STUM SYT17 CPZ EML3 EYS SACS PPIL2 NOTCH3	1.96e-07	145	188	8	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 LAMA3 ITGA9 GRIP1 PLEKHG4B P3H2 SBSPON PKHD1	9.71e-07	179	188	8	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 TRPC4 P2RX7 TRIM9 PLXNA4 PREX1 ALK	1.06e-06	181	188	8	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 TRPC4 P2RX7 TRIM9 PLXNA4 PREX1 ALK	1.24e-06	185	188	8	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 P3H2 HPN CFAP221 PKHD1 PAX2 MCF2L UNC5D	1.35e-06	187	188	8	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 ITGA9 GRIP1 PLEKHG4B BMPR1B PLXNA4 LNX1 NOTCH3	1.52e-06	190	188	8	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 P3H2 HPN CFAP221 PLXNA4 PKHD1 PAX2 MCF2L	1.52e-06	190	188	8	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KLHL24 LAMA3 SHC3 P3H2 CFAP221 PKHD1 CYP4X1 FBN3	1.64e-06	192	188	8	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ARHGEF19 LAMA3 P3H2 HPN PKHD1 LRP2	1.64e-06	192	188	8	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BACH2 TRPC4 GRIP1 EYS ASS1 FBLIM1 ALK UNC5D	1.71e-06	193	188	8	5581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 PLEKHG4B P3H2 HPN PKHD1 LRP2	1.78e-06	194	188	8	c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	1.78e-06	194	188	8	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 TMPRSS13 LAMA3 GRIP1 BMPR1B P3H2 PKHD1 LRP2	2.07e-06	198	188	8	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 DUSP4 MUC5B GRIP1 PLEKHG4B BMPR1B LNX1 NOTCH3	2.07e-06	198	188	8	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 DUSP4 MUC5B GRIP1 PLEKHG4B BMPR1B LNX1 NOTCH3	2.23e-06	200	188	8	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	USP53 FRAS1 ADAMTS2 BACH2 TRPC4 ADGRB3 LAMA2 FBXL7	2.23e-06	200	188	8	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MASP1 IZUMO4 AOC1 BACH2 LAMA2 SBSPON PLXNA4	4.03e-06	153	188	7	1524557514668f515ac1bbe847611f564b265b42
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LAMA2 MUC5B TECTA GRIP1 PKHD1 LRP2	5.41e-06	160	188	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LAMA2 MUC5B TECTA GRIP1 PKHD1 LRP2	5.41e-06	160	188	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 NOTCH3	5.64e-06	161	188	7	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE LAMA3 SALL4 PLEKHG4B PKHD1 FBN3	6.60e-06	108	188	6	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 PAPLN GRIP1 SBSPON PKHD1 LRP2 PAX2	7.45e-06	168	188	7	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 POLA1 TRPC4 LAMA2 CCN4 PLXNA4 FBLIM1	7.75e-06	169	188	7	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 STARD9 NOTCH3	8.69e-06	172	188	7	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 STARD9 NOTCH3	8.69e-06	172	188	7	553701349444eb366df3c11f54bb093434f153c6
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE DUSP4 CHN1 ZNF496 SSPOP SHC3 NOTCH3	9.02e-06	173	188	7	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE DUSP4 CHN1 ZNF496 SSPOP SHC3 NOTCH3	9.02e-06	173	188	7	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SNX20 TGFA EYS HPN ZNF488 PREX1 NLRC3	9.37e-06	174	188	7	5e6050d20a5b27640f6a200441125b8ceba123c8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 LAMA2 CCN4 KCND1 TRIM9 CYP4X1 NOTCH3	9.73e-06	175	188	7	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 CHN1 GRIP1 BMPR1B EYS CFAP221 ASS1	1.01e-05	176	188	7	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FRAS1 SALL4 ITGA9 CHN1 GRIP1 PLEKHG4B PLXNA4	1.05e-05	177	188	7	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BACH2 ADGRB3 LAMA2 FBXL7 SBSPON PLXNA4 LTBP3	1.05e-05	177	188	7	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 LAMA3 ITGA9 GRIP1 PLEKHG4B SBSPON PKHD1	1.05e-05	177	188	7	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	ZXDC MYO7A DUSP4 ZNF780B CHAMP1 SCX NOTCH3	1.09e-05	178	188	7	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPLN GRIP1 P3H2 SBSPON PKHD1 LRP2 PAX2	1.09e-05	178	188	7	544379f5a6145429762258d426b876bb36c112f5
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	ARHGEF19 RNF166 GNLY ZNF235 ZNF236 ZNF630 ANXA2R	1.13e-05	179	188	7	10c7d371937d9d93c12c8d3465430ef9e0c2ec81
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 STUM TRPC4 CPZ TGFA PLEKHG4B CCN4	1.17e-05	180	188	7	7a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 ADAMTS2 LAMA2 CCN4 TRIM9 CYP4X1 NOTCH3	1.21e-05	181	188	7	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 LAMA3 ITGA9 GRIP1 PLEKHG4B SBSPON PKHD1	1.21e-05	181	188	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 ADAMTS2 LAMA2 CCN4 TRIM9 CYP4X1 NOTCH3	1.21e-05	181	188	7	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 P2RX7 TRIM9 PLXNA4 PREX1 ALK	1.25e-05	182	188	7	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 HPN CFAP221 PKHD1 PAX2 MCF2L UNC5D	1.25e-05	182	188	7	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 GRIP1 P3H2 HPN PKHD1 LRP2 PAX2	1.25e-05	182	188	7	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 GRIP1 SALL1 HPN PKHD1 LRP2 PAX2	1.30e-05	183	188	7	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYT17 LAMA2 PAPLN CHN1 CCN4 ADAMTS18 NOTCH3	1.35e-05	184	188	7	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 LAMA3 ITGA9 GRIP1 PLEKHG4B SBSPON PKHD1	1.39e-05	185	188	7	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 LAMA3 ITGA9 GRIP1 PLEKHG4B SBSPON PKHD1	1.44e-05	186	188	7	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MASP1 PAPLN VWCE ZNF462 PKHD1 LRP2 UNC5D	1.44e-05	186	188	7	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 HPN PKHD1 LRP2 ADAMTS18	1.44e-05	186	188	7	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN GLG1 HPN ASS1 PKHD1 LRP2 MCF2L	1.44e-05	186	188	7	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 GRIP1 PLEKHG4B BMPR1B PLXNA4 LNX1 NOTCH3	1.50e-05	187	188	7	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 LAMA3 SHC3 PLEKHG4B P3H2 CYP4X1 FBN3	1.50e-05	187	188	7	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	1.50e-05	187	188	7	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POLA1 ADGRB3 ITGA9 CHN1 FBXL7 STARD9 PREX1	1.50e-05	187	188	7	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	USP53 FRAS1 ADAMTS2 TRPC4 ADGRB3 LAMA2 FBXL7	1.50e-05	187	188	7	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN P3H2 HPN ASS1 PKHD1 LRP2 MCF2L	1.50e-05	187	188	7	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ITGA9 ZNF462 FBXL7 P3H2 CFAP221 PAX2 FBLIM1	1.50e-05	187	188	7	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 STARD9 NOTCH3	1.50e-05	187	188	7	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN P3H2 HPN ASS1 PKHD1 LRP2 MCF2L	1.50e-05	187	188	7	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 GRIP1 P3H2 HPN PKHD1 LRP2 PAX2	1.50e-05	187	188	7	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 STARD9 NOTCH3	1.50e-05	187	188	7	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MASP1 TRPC4 LAMA2 CHN1 KLHL38 UNC5D NOTCH3	1.50e-05	187	188	7	8ee3bf885897efd634c3a0567637142a9f55e693
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ADGRB3 LAMA2 CCN4 TRIM9 STARD9 NOTCH3	1.55e-05	188	188	7	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNC ADGRB3 ITGA9 SCX SBSPON PLXNA4 SPOCD1	1.55e-05	188	188	7	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GRIP1 CCN4 BMPR1B SBSPON ASS1 LRP2 CYP4X1	1.55e-05	188	188	7	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	1.55e-05	188	188	7	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	BACH2 ADGRB3 LAMA2 ITGA9 CHN1 FBXL7 PLXNA4	1.60e-05	189	188	7	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ARHGEF19 LAMA3 P3H2 PKHD1 LRP2	1.60e-05	189	188	7	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 LAMA3 GRIP1 P3H2 PKHD1 LRP2	1.60e-05	189	188	7	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	MASP1 DUSP4 TRPC4 LAMA2 CHN1 STARD9 NOTCH3	1.60e-05	189	188	7	d7ed96add29f219183c802895fbff519b627f635
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	1.66e-05	190	188	7	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 LAMA3 PLEKHG4B P3H2 PKHD1 LRP2	1.66e-05	190	188	7	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ERBB3 MUC5B GRIP1 PLEKHG4B BMPR1B CYP4X1 LNX1	1.66e-05	190	188	7	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 BMPR1B P3H2 PKHD1 LNX1	1.71e-05	191	188	7	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	USP53 IZUMO4 AOC1 DUSP4 RELB ZNF467 KIF2A	1.77e-05	192	188	7	2c69f3f388b69fb1c1968c923cdbab90658883dd
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	USP53 IZUMO4 AOC1 DUSP4 RELB ZNF467 KIF2A	1.77e-05	192	188	7	d5a7b546ebfb2e757dd9c64cb1b651f6ed0e0fc7
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 TMPRSS13 GRIP1 BMPR1B P3H2 PKHD1 LRP2	1.83e-05	193	188	7	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 TMPRSS13 GRIP1 BMPR1B P3H2 PKHD1 LRP2	1.83e-05	193	188	7	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 GRIP1 P3H2 HPN PKHD1 LRP2 PAX2	1.83e-05	193	188	7	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 LAMA3 SHC3 P3H2 CFAP221 PKHD1 FBN3	1.83e-05	193	188	7	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 TRPC4 LAMA2 CCN4 FBXL7 PLXNA4 FBLIM1	1.89e-05	194	188	7	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 GRIP1 P3H2 HPN CFAP221 PKHD1 PAX2	1.89e-05	194	188	7	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB3 PAPLN VWCE P3H2 SBSPON PKHD1 LRP2	1.89e-05	194	188	7	70185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IZUMO4 AOC1 DUSP4 GPT RELB VWCE KIF2A	1.89e-05	194	188	7	f0467d81063a9b19783906c456935ef8318b9b98
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 TRPC4 LAMA2 CCN4 FBXL7 PLXNA4 FBLIM1	1.89e-05	194	188	7	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MASP1 STUM SYT17 SCX SBSPON PLXNA4 NOTCH3	1.89e-05	194	188	7	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 TRPC4 LAMA2 CCN4 BMPR1B FBXL7 FBLIM1	1.96e-05	195	188	7	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	1.96e-05	195	188	7	98dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	USP53 FRAS1 TRPC4 ADGRB3 LAMA2 FBXL7 PLXNA4	1.96e-05	195	188	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 TRPC4 LAMA2 CCN4 FBXL7 FBLIM1 NOTCH3	1.96e-05	195	188	7	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 TRPC4 LAMA2 SHC3 BMPR1B FBXL7 FBLIM1	2.02e-05	196	188	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	PCW_10-12-Epithelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	2.02e-05	196	188	7	9bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LAMA3 GRIP1 P3H2 HPN PKHD1 LRP2	2.02e-05	196	188	7	0a34a0009f479384f1994c6f977f942699a132c8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELE ADGRB3 ITGA9 CHN1 FBXL7 STARD9 PREX1	2.02e-05	196	188	7	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	TRAF6 ZNF211 TUBGCP2 IDS EML3 GLG1 RECQL5 KIF2A PAX5 SGSM3 MCF2L NOTCH3	7.52e-08	196	185	12	5519_DN
Drug	Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; HL60; HT_HG-U133A	KLHL24 ZBTB17 RELB TGFA P2RX7 GLG1 SQSTM1 RECQL5 LTBP3 NOTCH3	2.28e-06	180	185	10	2410_UP
Drug	Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	TSSK2 TUBGCP2 ZNF467 BMPR1B TRANK1 RECQL5 UNKL PPIL2 PAX2 MCF2L	5.10e-06	197	185	10	4620_UP
Drug	Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A	ZNF134 RCAN1 POLA1 LAMA3 TUBGCP2 ZNF236 LRP2 ZNF74 PPIL2 PAX5	5.33e-06	198	185	10	5495_DN
Drug	vinylene	RAG1 RNF166 SALL4 ZNF235 ZNF467 ZNF496 ZNF462 SALL1 RNF125 MZF1 TRIM28	5.56e-06	245	185	11	CID000006326
Disease	Craniofacial Abnormalities	MASP1 RCAN1 SALL4 BMPR1B UNC45B LRP2 LTBP3 NOTCH1	4.12e-06	156	173	8	C0376634
Disease	Cryptophthalmos syndrome	FRAS1 GRIP1	1.02e-04	3	173	2	C0265233
Disease	Duane Retraction Syndrome, Type 2	SALL4 CHN1	1.02e-04	3	173	2	C0751083
Disease	Duane Retraction Syndrome, Type 3	SALL4 CHN1	1.02e-04	3	173	2	C0751084
Disease	Type 1 Duane Retraction Syndrome	SALL4 CHN1	1.02e-04	3	173	2	C0994516
Disease	Duane retraction syndrome (is_implicated_in)	SALL4 CHN1	1.02e-04	3	173	2	DOID:12557 (is_implicated_in)
Disease	FRASER SYNDROME 1	FRAS1 GRIP1	1.02e-04	3	173	2	C4551480
Disease	Okihiro Syndrome	SALL4 CHN1	1.02e-04	3	173	2	C1623209
Disease	severe combined immunodeficiency (implicated_via_orthology)	RAG1 PRKDC	1.02e-04	3	173	2	DOID:627 (implicated_via_orthology)
Disease	Fraser syndrome (implicated_via_orthology)	FRAS1 GRIP1	2.03e-04	4	173	2	DOID:0090001 (implicated_via_orthology)
Disease	diabetic foot, neuropathy	LNX1 UNC5D	2.03e-04	4	173	2	EFO_0004149, EFO_1001459
Disease	X-24020 measurement	AOC1 TUBGCP2	3.38e-04	5	173	2	EFO_0022128
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	3.38e-04	5	173	2	EFO_0004647, EFO_0006952
Disease	Duane Retraction Syndrome	SALL4 CHN1	3.38e-04	5	173	2	C0013261
Disease	brain cancer (implicated_via_orthology)	NR2E1 NOTCH1 NOTCH3	4.66e-04	26	173	3	DOID:1319 (implicated_via_orthology)
Disease	clubfoot (implicated_via_orthology)	FRAS1 GRIP1	5.05e-04	6	173	2	DOID:11836 (implicated_via_orthology)
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH1 NOTCH3	7.04e-04	7	173	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH1 NOTCH3	7.04e-04	7	173	2	DOID:3620 (implicated_via_orthology)
Disease	intestinal cancer (implicated_via_orthology)	ERBB3 NOTCH1 NOTCH3	8.67e-04	32	173	3	DOID:10155 (implicated_via_orthology)
Disease	nicotine dependence symptom count, depressive symptom measurement	AOC1 UNC45B P3H2 PREX1	1.00e-03	75	173	4	EFO_0007006, EFO_0009262
Disease	urate measurement, bone density	FRAS1 BACH2 ADGRB3 SHC3 CCN4 EYS SALL1 ASS1 HELZ2 PLXNA4 PRKDC	1.12e-03	619	173	11	EFO_0003923, EFO_0004531
Disease	asparaginase-induced acute pancreatitis	SBSPON ADAMTS18	1.20e-03	9	173	2	EFO_1001507
Disease	renal Wilms' tumor (is_implicated_in)	SALL1 PAX2	1.49e-03	10	173	2	DOID:5176 (is_implicated_in)
Disease	Malignant neoplasm of breast	ERBB3 CTU2 TRPC4 LAMA2 TECTA ITGA9 STC2 UNC45B P3H2 KLHDC10 SPOCD1 ALK NOTCH1 NOTCH3 ZNF646	1.71e-03	1074	173	15	C0006142
Disease	Congenital small ears	FRAS1 GRIP1 SALL1	1.79e-03	41	173	3	C0152423
Disease	Congenital Abnormality	SALL1 NOTCH1	1.82e-03	11	173	2	C0000768
Disease	osteoarthritis, hip	MASP1 TGFA P3H2 LTBP3	2.14e-03	92	173	4	EFO_1000786
Disease	Non-Small Cell Lung Carcinoma	TGFA ZNF462 CHFR ALK NOTCH3	2.31e-03	156	173	5	C0007131
Disease	Alzheimer disease, gastroesophageal reflux disease	ERBB3 ADGRB3 RELB SALL1 TRIM9 ADAMTS18	2.33e-03	228	173	6	EFO_0003948, MONDO_0004975
Disease	Hypodontia	TGFA LTBP3	2.97e-03	14	173	2	C0020608
Disease	Impaired cognition	CR1 NOTCH3	2.97e-03	14	173	2	C0338656
Disease	Down syndrome (implicated_via_orthology)	RCAN1 DOP1B	3.41e-03	15	173	2	DOID:14250 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 NOTCH1	3.41e-03	15	173	2	C0496930
Disease	hepatoblastoma (is_marker_for)	SALL4 SALL1	3.41e-03	15	173	2	DOID:687 (is_marker_for)
Disease	Benign neoplasm of bladder	ERBB3 NOTCH1	3.41e-03	15	173	2	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 NOTCH1	3.41e-03	15	173	2	C0154091
Disease	superior parietal cortex volume measurement	ADGRB3 SHC3	3.41e-03	15	173	2	EFO_0010330
Disease	Myopia	LAMA2 P3H2	3.41e-03	15	173	2	C0027092
Disease	episodic memory	FASTKD2 SYNGAP1 QSOX1	3.55e-03	52	173	3	EFO_0004333
Disease	migraine disorder, fasting blood insulin measurement	ERBB3 ADGRB3	3.89e-03	16	173	2	EFO_0004466, MONDO_0005277
Disease	Limb Deformities, Congenital	SALL4 SALL1	4.39e-03	17	173	2	C0206762
Disease	Carcinoma of bladder	ERBB3 NOTCH1	4.92e-03	18	173	2	C0699885
Disease	Intellectual Disability	CHAMP1 SYNGAP1 ZNF462 RNF125 SACS ASS1 LRP2 SNX27	5.04e-03	447	173	8	C3714756
Disease	Polydactyly	FRAS1 SALL4 GRIP1 SALL1	5.06e-03	117	173	4	C0152427
Disease	Malignant neoplasm of skin	ERBB3 NOTCH1 NOTCH3	5.06e-03	59	173	3	C0007114
Disease	Skin Neoplasms	ERBB3 NOTCH1 NOTCH3	5.06e-03	59	173	3	C0037286

Protein segments in the cluster

Peptide	Gene	Start	Entry
IQPGHLCCVRISEDK	TDRD5	526	Q8NAT2
CDKENRTPLIQAVHC	ANKRD20A1	96	Q5TYW2
RTPLIQAVHCQEEAC	ANKRD20A1	101	Q5TYW2
GQARDHCRPRALCVI	GPT	226	P24298
HNRPRRDCVAEGKVC	ERBB3	486	P21860
FVCRKDAACQRPHED	BACH2	141	Q9BYV9
SQERAARVRCELCPH	MLLT6	56	P55198
ARVRCELCPHKDGAL	MLLT6	61	P55198
CDKENRTPLIQAVHC	ANKRD20A8P	96	Q5CZ79
RTPLIQAVHCQEEAC	ANKRD20A8P	101	Q5CZ79
HSRECLALKQARCSP	ANTXRL	516	A6NF34
CRSVLHKDIGPCRAA	ADGRB3	1196	O60242
CDKENRTPLIQAVHC	ANKRD20A4P	96	Q4UJ75
RTPLIQAVHCQEEAC	ANKRD20A4P	101	Q4UJ75
RTPLIQAVHCQEEAC	ANKRD20A5P	101	A0PJZ0
AVCRKVLEAPALHCE	DGKQ	136	P52824
SRLCNLRPCDVDIHT	CCN4	251	O95388
DCHDRCLAFTDVAPR	AOC1	176	P19801
DLDECVSQEHRCSPR	FBN3	1321	Q75N90
RNECREIPNVCSHGD	FBN3	1806	Q75N90
TEVCDSGCLLERRHP	ANXA2R	136	Q3ZCQ2
IPHQRRSIECCTERN	BMPR1B	86	O00238
CEFVRHCIAKSQERV	ASS1	331	P00966
LEETCNRRACPAHPV	ADAMTS18	1106	Q8TE60
AKHCNDARPESRRAC	ADAMTS2	956	O95450
ISDHCRGRLEVPCQS	MUC5B	5316	Q9HC84
REPCGHLKTSCEEQI	RC3H2	761	Q9HBD1
CHLDPRVFVDGLCRA	RCAN1	71	P53805
ADPVETNCKHVFCRV	RAG1	301	P15918
HPDKDVRLLVACCLA	PDS5B	71	Q9NTI5
HCDLTPKTCENFIRL	PPIL2	296	Q13356
RELCSACHNERLDVP	QSOX1	506	O00391
KDCTDGICRVRLRPH	RELB	201	Q01201
GCRVIQRILEHCTAE	PUM2	886	Q8TB72
DKLTPIHDRIFCCRS	PSMB6	66	P28072
PCDISRQLRVSHGCV	PAX5	51	Q02548
CDKENRTPLIQAVHC	ANKRD20A2P	96	Q5SQ80
RTPLIQAVHCQEEAC	ANKRD20A2P	101	Q5SQ80
RQCSICEAPRHKPDL	CAPN15	21	O75808
VLRFSVCDVVLDHCP	ARHGEF19	446	Q8IW93
VCDVVLDHCPAFRRV	ARHGEF19	451	Q8IW93
GRLHCPRQECIQAFD	KCND1	101	Q9NSA2
TPCKNAGTCHVVDRR	NOTCH1	66	P46531
RGEVRCHKQACLPLR	FRAS1	246	Q86XX4
QHEAVCKDEINRPRC	EYS	576	Q5T1H1
FCPHVLGCRDQVIAE	LAMA3	1161	Q16787
CELCHTEFAVEKRPR	MARCHF2	106	Q9P0N8
GPCETCRQEVEKHCR	NFXL1	436	Q6ZNB6
EKLCADRLICSVFPH	NLRC3	186	Q7RTR2
PDAAVCARAINVLHC	NLRC3	556	Q7RTR2
FPVCHDTEERCRLVL	EDRF1	591	Q3B7T1
RLHCLAPTANICEDI	DOP1B	901	Q9Y3R5
HAGFVEICVAVCRPE	PLXNA4	926	Q9HCM2
GFPAARRCHSCVQIK	KLHDC10	311	Q6PID8
SKVQLDCRECPEGHV	FLNC	2546	Q14315
LARAHLRDEEKSCPC	GNLY	31	P22749
RSDVDECRVGEPCRH	NOTCH3	156	Q9UM47
PFREHCTQVLQRCDL	LNX1	106	Q8TBB1
EKPTCEAVRCDAVHQ	SELE	421	P16581
RECGHDVTCPVAKEI	TUBGCP2	461	Q9BSJ2
CKVNVEGIHCDRCRP	LAMA2	1136	P24043
EREFPCHRLVLAACS	KLHL40	41	Q2TBA0
DVVPSSFCVKHCRNL	NLRP2	636	Q9NX02
TGVVVLCEALRHPEC	NLRP4	936	Q96MN2
IPKIFRCDRHNDCGD	LRP2	3006	P98164
LVCQHECVRELATRP	P3H2	281	Q8IVL5
LRACCIPSNEDHRRV	DEFB118	51	Q96PH6
GHCRKICRVNEVPEA	DEFB127	31	Q9H1M4
VARAHNVPVLVCCET	EIF2B4	426	Q9UI10
LICEEPTCRNRTRHL	POLA1	1346	P09884
PHTQRLLEVISVCDC	HPN	126	P05981
LRRVLEGHVFDVNCC	PAAF1	126	Q9BRP4
PCDISRQLRVSHGCV	PAX2	51	Q02962
RCPGESSHICDFIRK	PPT1	151	P50897
KCRVHTNPDRRCTEL	ITGA9	86	Q13797
ADPIDEHRICVCVRK	KIF2A	216	O00139
QLPESHRCLEELCCR	P2RX7	486	Q99572
ESCREDVTRVCPKHT	GLG1	116	Q92896
CDKENRTPLIQAVHC	ANKRD20A3P	96	Q5VUR7
RTPLIQAVHCQEEAC	ANKRD20A3P	101	Q5VUR7
TCRCPVERICKNHIL	CHFR	341	Q96EP1
CVEGKEFPCHRAVLS	KLHL24	71	Q6TFL4
RPCRHICEGLREVCQ	CPZ	116	Q66K79
RCELSVRAGHCKTPE	CR1	1386	P17927
ETEIHVGRCLNSRPC	DEFB108A	41	A8MXU0
RHCKRCVIEHTNPAF	FBXL7	476	Q9UJT9
ELRKPSARLECDHCS	CHAMP1	6	Q96JM3
CEDQPHRRCTLQSVL	FRMPD2	141	Q68DX3
CLALNPEHQERCREE	CYP4X1	331	Q8N118
KRGIIPLDAHCCVEV	DEF6	256	Q9H4E7
CIHRAAGPLLTDECR	MACROD1	186	Q9BQ69
EKSLCFRLVSPEHQC	LTBP3	401	Q9NS15
PRVCHVENGRVVACF	MBNL3	41	Q9NUK0
TCKIVDCRAPGELEH	MASP1	361	P48740
VDSIRPKCQELRHLC	MCF2L	426	O15068
DICAFCHKTVSPREL	FBLIM1	181	Q8WUP2
DCVRCLAVHPDGVRV	EML3	306	Q32P44
RCPVPSFHVELCREG	IDS	421	P22304
EAPHPRRITCTCEVE	CHN1	26	P15882
FIRECVERHSVCPEG	HELZ2	931	Q9BYK8
HVRTRDFDCCLVVPL	GRIP1	1056	Q9Y3R0
IRREVFCCGTCHELK	FAM240B	6	A0A1B0GVZ2
CPERGRVLCHRASVF	DHX37	1026	Q8IY37
FEGPKHEVLRRCLCA	DHX40	611	Q8IX18
IDAVKDCRGRVLVHC	DUSP4	266	Q13115
KATDPNECIICHRVL	SALL1	701	Q9NSC2
ATTDPNECLICHRVL	SALL4	561	Q9UJQ4
VRQVLRKCAHLGCAE	SACS	631	Q9NZJ4
IIESRIDCQHRCGIF	IZUMO4	121	Q1ZYL8
FTDRTLARCPHCRKV	PIP4P1	186	Q86T03
PVVVIRAGDAFCRDC	CTU2	36	Q2VPK5
EHRICVCVRKRPLNQ	KIF2B	211	Q8N4N8
PVDKTHRNQCRACRL	NR2E1	61	Q9Y466
CIRVHCKGDDTLLVP	CFAP221	136	Q4G0U5
QCLRCGHEFKPEEPR	STK11IP	671	Q8N1F8
GERTCGVHELICIRK	SYT14	6	Q8NB59
PVRVCDSCHALLIQR	RUFY2	586	Q8WXA3
KARRCQTEPCEGCEH	SSPOP	1956	A2VEC9
RHCVIGKVSVPLCEV	SYT17	286	Q9BSW7
ESHRSDPNRVVCPIC	RNF166	171	Q96A37
CSKVVLDNIHGCPLR	FASTKD2	366	Q9NYY8
RCHVLEKIVEPRGCF	PREX1	866	Q8TCU6
RVARHFQCTDPKNCS	SGSM3	441	Q96HU1
KPHRTFRFNECVCTP	POLR3A	481	O14802
AKDPVNRRACHILEC	SHC3	271	Q92529
DLRHPKRIFFCIDNC	PRAMEF27	446	A3QJZ7
PCDIRHVSPRKIECT	PKHD1	296	P08F94
HECLENTTRCFLEKP	STARD9	3161	Q9P2P6
NREDLRHLCICSVDP	DIS3	466	Q9Y2L1
EKKECRRDHRPPCAQ	SQSTM1	101	Q13501
IHRDIAARNCLLTCP	ALK	1246	Q9UM73
RAARVRCELCPHKDG	MLLT10	76	P55197
DVVSKCIRCHFQPLL	USP53	331	Q70EK8
CDHCQNPTAVRRRLE	RECQL5	431	O94762
CAVLLCHRDLDRPAE	SNX20	231	Q7Z614
QPRCAAIRLKSDCSH	TECTA	1386	O75443
RFLVQEDKPACVCHS	TGFA	61	P01135
LRCDPERDHFRKICE	UNC45B	366	Q8IWX7
KRREEALACPVCQEH	ZNF488	311	Q96MN9
QRIHTGERPFECQEC	ZNF157	461	P51786
KHDDDRRFTCPVEGC	ZXDC	381	Q2QGD7
RESCPKHAVRCDGVV	TMPRSS13	201	Q9BYE2
GHLPCIVRRTSKEAC	ZP1	241	P60852
DCAVCLEVLHQPVRT	RNF125	36	Q96EQ8
KVRRVDQCSCPAVHS	SBSPON	246	Q8IVN8
LCKVVNSHCVFPREL	SYNGAP1	551	Q96PV0
DRRSCNLHPCPETKR	PAPLN	351	O95428
FLRELERCQHCPLAV	PLEKHG4B	866	Q96PX9
VLCGARTDLPDRHVC	STUM	76	Q69YW2
HRFGCISRKCPAIRE	STC2	116	O76061
DVCVVRLCPHGARDT	SPOCD1	926	Q6ZMY3
IHILKDCPRRQVSCD	TRAF6	176	Q9Y4K3
QRTHTGERPFKCENC	ZNF774	366	Q6NX45
PCHRQGEQEETALCR	ZSCAN25	131	Q6NSZ9
RKTHLGERPAECAEC	ZNF672	386	Q499Z4
HSCVDVNECRRPLER	VWCE	216	Q96DN2
IHADPRRFRCSECGK	ZNF646	1251	O15015
CIVHVSEKPFTCREI	ZNF211	176	Q13398
CRHEVEQGCAVLRAT	TLNRD1	156	Q9H1K6
EIIFPHCACDSRRKG	SNX27	426	Q96L92
IEHCRIHTGEKPFEC	ZNF780B	321	Q9Y6R6
SPECEHLRIRECTAP	UNC5D	321	Q6UXZ4
ACRERAHGAVLRPCQ	UNKL	641	Q9H9P5
CGRPQTECRHKSIEL	PRKDC	1176	P78527
QRVHTREKPFECSEC	ZNF630	366	Q2M218
ITCPQCHRSLILDDR	TRIM9	126	Q9C026
QRAIHERGEAVCPTC	ZNF512B	501	Q96KM6
DPQHISRAVCNICKR	ZBED6	276	P86452
RIHTGEKPFSCRECS	ZBTB17	326	Q13105
RSRREQEKPHECSVC	ZNF496	426	Q96IT1
TCDVCGKVFPHRSRL	ZNF316	346	A6NFI3
KFCVEVHPTLRAICN	ZNF462	1971	Q96JM2
RRIHTGEKPFDCSQC	ZNF74	491	Q16587
IRIHTGERPFKCSEC	ZNF236	216	Q9UL36
QRTHTGEKPFRCNEC	ZNF286B	486	P0CG31
DQRPVCLVCRESQEH	TRIM4	101	Q9C037
HRPLRRCEAKCLVQS	TRANK1	2166	O15050
QRVHTRERPFECKEC	ZNF623	226	O75123
DEKPCRVHAARCGLQ	SCX	36	Q7RTU7
RVHSREKPFDCEECG	ZNF275	201	Q9NSD4
HLDAELRCPVCRQAV	TRIM50	46	Q86XT4
LCPHGELCISENERR	USP48	651	Q86UV5
ACHTRVHDRQKEFPC	ZNF425	486	Q6IV72
HRVDFPRSKNLTCEC	TSSK2	231	Q96PF2
QRVHTGEKPFRCNVC	ZNF235	506	Q14590
RIHTESKPFECIECG	ZNF134	336	P52741
HTGERPFPCTECEKR	ZNF467	266	Q7Z7K2
VSVPRPHEVRCNCVE	TRPC4	166	Q9UBN4
QRVHTTERPFKCGEC	ZNF814	651	B7Z6K7
EPLCETCVEAHQRVK	TRIM28	171	Q13263
GAVRFCDRCHLIKPD	ZDHHC15	126	Q96MV8
RRIHTGEKPHKCEVC	ZNF311	546	Q5JNZ3
ERIHTRGVKPFECDQ	ZNF473	581	Q8WTR7
VSICAGAREIPCHRN	KLHL38	36	Q2WGJ6
QECAHCSRALLQERP	LRRC14	66	Q15048
RFLQSRKHCPLAIDC	MYO7A	1856	Q13402
RRVHTGEQPFRCAEC	MZF1	431	P28698
RTHRREKPFACQDCG	MZF1	701	P28698