Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionTRAIL receptor activity

TNFRSF10D TNFRSF10C TNFRSF10A

4.57e-074983GO:0036463
GeneOntologyMolecularFunctionTRAIL binding

TNFRSF10D TNFRSF10C TNFRSF10A

1.14e-065983GO:0045569
GeneOntologyMolecularFunctiondeath receptor activity

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4

3.06e-0621984GO:0005035
GeneOntologyMolecularFunctiontumor necrosis factor receptor activity

TNFRSF10C TNFRSF10A TNFRSF4

2.44e-0512983GO:0005031
GeneOntologyMolecularFunctionzinc ion binding

EPRS1 TRAF6 SLC11A2 ZNF875 NSD1 GRIN2A GRIN2B ADAMTS5 TRIM64B EHMT2 MIB1 ADAMTS20 POLR1B NR5A1

1.12e-048919814GO:0008270
GeneOntologyMolecularFunctionToll-like receptor 2 binding

TLR6 TLR1

1.42e-044982GO:0035663
GeneOntologyMolecularFunctioncysteine-type endopeptidase activator activity involved in apoptotic process

TNFRSF10D TNFRSF10C TNFRSF10A

3.82e-0429983GO:0008656
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

4.93e-047982GO:0005234
GeneOntologyMolecularFunctionpeptidase activator activity involved in apoptotic process

TNFRSF10D TNFRSF10C TNFRSF10A

5.13e-0432983GO:0016505
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B

6.55e-048982GO:0022849
GeneOntologyMolecularFunctionlaminin-1 binding

NTN4 PXDN

6.55e-048982GO:0043237
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

6.55e-048982GO:0004972
GeneOntologyMolecularFunctionlipopeptide binding

TLR6 TLR1

1.05e-0310982GO:0071723
GeneOntologyMolecularFunctionscaffold protein binding

GIT1 GRIN2A GRIN2B CACNA1G

1.14e-0393984GO:0097110
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

NSD1 KMT2D EHMT2

1.31e-0344983GO:0140938
GeneOntologyMolecularFunctionamyloid-beta binding

GRIN2A GRIN2B TLR6 FZD5

1.60e-03102984GO:0001540
GeneOntologyMolecularFunctionstructural constituent of postsynaptic specialization

RAPSN GIT1

1.80e-0313982GO:0098879
GeneOntologyMolecularFunctiontransition metal ion binding

EPRS1 TRAF6 SLC11A2 ZNF875 NSD1 GRIN2A GRIN2B ADAMTS5 TRIM64B EHMT2 MIB1 ADAMTS20 POLR1B NR5A1

1.96e-0311899814GO:0046914
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

2.09e-0314982GO:0016595
GeneOntologyMolecularFunctioncysteine-type endopeptidase regulator activity involved in apoptotic process

TNFRSF10D TNFRSF10C TNFRSF10A

2.37e-0354983GO:0043028
GeneOntologyBiologicalProcessactivation of NF-kappaB-inducing kinase activity

TRAF6 TNFRSF10A TLR6 TLR1

1.13e-0617994GO:0007250
GeneOntologyBiologicalProcessTRAIL-activated apoptotic signaling pathway

TNFRSF10D TNFRSF10C TNFRSF10A

2.29e-0512993GO:0036462
GeneOntologyBiologicalProcessactivation-induced cell death of T cells

TNFRSF10C TNFRSF10A TNFRSF4

4.68e-0515993GO:0006924
GeneOntologyBiologicalProcessdetection of bacterial lipopeptide

TLR6 TLR1

6.82e-053992GO:0070340
GeneOntologyBiologicalProcesspositive regulation of JUN kinase activity

TRAF6 TLR6 FZD8 FZD5

8.96e-0549994GO:0043507
GeneOntologyBiologicalProcessdetection of bacterial lipoprotein

TLR6 TLR1

1.36e-044992GO:0042494
GeneOntologyBiologicalProcessSpemann organizer formation

WNT1 FZD5

1.36e-044992GO:0060061
MousePhenoabnormal midbrain-hindbrain boundary development

WNT1 HIRA LMX1B

8.82e-068773MP:0004096
MousePhenoabnormal interleukin-12 secretion

TRAF6 TNFRSF10D TNFRSF10C TNFRSF10A TLR6

2.25e-0562775MP:0008662
MousePhenoabnormal operant conditioning behavior

GIT1 GPRIN3 GRIN2B

4.42e-0513773MP:0002803
MousePhenodecreased susceptibility to Herpesvirales infection induced morbidity/mortality

TNFRSF10D TNFRSF10C TNFRSF10A

5.60e-0514773MP:0031025
MousePhenoabnormal midbrain-hindbrain boundary morphology

WNT1 HIRA LMX1B

6.97e-0515773MP:0012132
MousePhenodecreased rhombomere 1 size

WNT1 LMX1B

8.95e-053772MP:0012785
MousePhenoincreased circulating interleukin-12b level

TNFRSF10D TNFRSF10C TNFRSF10A

1.24e-0418773MP:0008647
MousePhenoabnormal rhombomere 1 morphology

WNT1 LMX1B

1.78e-044772MP:0012784
MousePhenoabsent midbrain-hindbrain boundary

WNT1 LMX1B

1.78e-044772MP:0012133
MousePhenoabnormal neuron number

NOG PDE6C GIT1 RREB1 CRB1 KMT2D PXDN WDR11 EGR3 LMX1B

1.92e-044567710MP:0008946
MousePhenodecreased neuron number

PDE6C GIT1 RREB1 CRB1 KMT2D PXDN WDR11 EGR3 LMX1B

2.15e-04376779MP:0008948
MousePhenodecreased susceptibility to Herpesvirales infection

TNFRSF10D TNFRSF10C TNFRSF10A

2.29e-0422773MP:0020917
MousePhenodecreased cellular sensitivity to gamma-irradiation

TNFRSF10D TNFRSF10C TNFRSF10A

2.29e-0422773MP:0003207
MousePhenoabnormal embryonic neuroepithelium morphology

ELOA2 HIRA WDR11 MIB1 LRP2

2.80e-04105775MP:0004261
MousePhenoabsent patella

PCSK5 LMX1B

2.96e-045772MP:0004694
MousePhenodecreased eye anterior chamber depth

PXDN LMX1B

2.96e-045772MP:0031212
DomainTNFR_c6

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

7.94e-0822965PF00020
DomainTNFR

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

1.95e-0726965SM00208
DomainTNFR_NGFR_1

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

3.48e-0729965PS00652
DomainTNFR_NGFR_2

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

3.48e-0729965PS50050
DomainFYVE

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

3.48e-0729965PF01363
DomainFYVE

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

3.48e-0729965SM00064
DomainTNFR_10

TNFRSF10D TNFRSF10C TNFRSF10A

5.24e-074963IPR020465
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

6.84e-0733965IPR001368
DomainZnf_FYVE-rel

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

7.99e-0734965IPR017455
DomainZnf_FYVE

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

1.42e-0638965IPR000306
DomainZF_FYVE

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

1.84e-0640965PS50178
DomainZnf_FYVE_PHD

PLEKHF1 NSD1 WDFY2 KMT2D MTMR4 ZFYVE21 FGD1

1.08e-05147967IPR011011
Domain-

TRAF6 RAPSN PLEKHF1 NSD1 WDFY2 TRIM64B KMT2D MTMR4 MIB1 ZFYVE21 FGD1

1.93e-0544996113.30.40.10
DomainZnf_RING/FYVE/PHD

TRAF6 RAPSN PLEKHF1 NSD1 WDFY2 TRIM64B KMT2D MTMR4 MIB1 ZFYVE21 FGD1

2.36e-054599611IPR013083
DomainPost-SET_dom

NSD1 KMT2D EHMT2

7.02e-0516963IPR003616
DomainPostSET

NSD1 KMT2D EHMT2

7.02e-0516963SM00508
DomainPOST_SET

NSD1 KMT2D EHMT2

7.02e-0516963PS50868
DomainNMDAR2_C

GRIN2A GRIN2B

7.82e-053962PF10565
DomainNMDAR2_C

GRIN2A GRIN2B

7.82e-053962IPR018884
DomainADAM_spacer1

ADAMTS5 ADAMTS16 ADAMTS20

2.16e-0423963IPR010294
DomainADAM_spacer1

ADAMTS5 ADAMTS16 ADAMTS20

2.16e-0423963PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS5 ADAMTS16 ADAMTS20

2.46e-0424963IPR013273
DomainToll-like_receptor

TLR6 TLR1

2.59e-045962IPR017241
DomainPEROXIDASE_1

MPO PXDN

3.87e-046962PS00435
DomainPep_M12B_propep

ADAMTS5 ADAMTS16 ADAMTS20

1.05e-0339963PF01562
DomainPeptidase_M12B_N

ADAMTS5 ADAMTS16 ADAMTS20

1.05e-0339963IPR002870
DomainDISINTEGRIN_1

ADAMTS5 ADAMTS16 ADAMTS20

1.13e-0340963PS00427
DomainReprolysin

ADAMTS5 ADAMTS16 ADAMTS20

1.13e-0340963PF01421
DomainADAM_MEPRO

ADAMTS5 ADAMTS16 ADAMTS20

1.13e-0340963PS50215
DomainDISINTEGRIN_2

ADAMTS5 ADAMTS16 ADAMTS20

1.13e-0340963PS50214
DomainPeptidase_M12B

ADAMTS5 ADAMTS16 ADAMTS20

1.13e-0340963IPR001590
DomainAn_peroxidase

MPO PXDN

1.15e-0310962PF03098
DomainHaem_peroxidase_animal

MPO PXDN

1.15e-0310962IPR019791
DomainHaem_peroxidase

MPO PXDN

1.15e-0310962IPR010255
DomainPEROXIDASE_3

MPO PXDN

1.15e-0310962PS50292
Domain-

MPO PXDN

1.15e-03109621.10.640.10
DomainSET

NSD1 KMT2D EHMT2

1.22e-0341963PF00856
DomainDisintegrin_dom

ADAMTS5 ADAMTS16 ADAMTS20

1.22e-0341963IPR001762
DomainGrowth_fac_rcpt_

PCSK5 LAMA3 CRB1 NTN4 LRP2

1.26e-03156965IPR009030
DomainFrizzled

FZD8 FZD5

1.40e-0311962IPR000539
DomainFrizzled

FZD8 FZD5

1.40e-0311962PF01534
DomainFrizzled

FZD8 FZD5

1.40e-0311962SM01330
DomainSET

NSD1 KMT2D EHMT2

1.70e-0346963SM00317
DomainEGF-like_dom

PCSK5 LAMA3 VWDE CRB1 LRP2 OTOG

1.80e-03249966IPR000742
DomainSET_dom

NSD1 KMT2D EHMT2

2.17e-0350963IPR001214
DomainSET

NSD1 KMT2D EHMT2

2.17e-0350963PS50280
DomainTIL_dom

LRP2 OTOG

2.29e-0314962IPR002919
DomainPLAC

PCSK5 ADAMTS16

2.29e-0314962PF08686
DomainVWF_type-D

VWDE OTOG

2.99e-0316962IPR001846
DomainLaminin_N

LAMA3 NTN4

2.99e-0316962IPR008211
DomainVWFD

VWDE OTOG

2.99e-0316962PS51233
DomainLamNT

LAMA3 NTN4

2.99e-0316962SM00136
DomainVWD

VWDE OTOG

2.99e-0316962SM00216
DomainLAMININ_NTER

LAMA3 NTN4

2.99e-0316962PS51117
DomainLaminin_N

LAMA3 NTN4

2.99e-0316962PF00055
DomainVWD

VWDE OTOG

2.99e-0316962PF00094
DomainFrizzled/SFRP

FZD8 FZD5

2.99e-0316962IPR015526
Domainaa-tRNA-synth_I_CS

EPRS1 LARS2

3.79e-0318962IPR001412
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

3.79e-0318962PF10613
DomainGlu/Gly-bd

GRIN2A GRIN2B

3.79e-0318962IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

3.79e-0318962SM00918
DomainIontro_rcpt

GRIN2A GRIN2B

3.79e-0318962IPR001320
DomainIono_rcpt_met

GRIN2A GRIN2B

3.79e-0318962IPR001508
DomainLig_chan

GRIN2A GRIN2B

3.79e-0318962PF00060
DomainPBPe

GRIN2A GRIN2B

3.79e-0318962SM00079
DomainTSP_1

ADAMTS5 ADAMTS16 ADAMTS20

4.18e-0363963PF00090
DomainPLAC

PCSK5 ADAMTS16

4.22e-0319962PS50900
DomainPLAC

PCSK5 ADAMTS16

4.22e-0319962IPR010909
DomainAA_TRNA_LIGASE_I

EPRS1 LARS2

4.22e-0319962PS00178
DomainTSP1

ADAMTS5 ADAMTS16 ADAMTS20

4.57e-0365963SM00209
DomainTSP1_rpt

ADAMTS5 ADAMTS16 ADAMTS20

4.57e-0365963IPR000884
DomainTSP1

ADAMTS5 ADAMTS16 ADAMTS20

4.57e-0365963PS50092
DomainFRI

FZD8 FZD5

4.68e-0320962SM00063
DomainRING

TRAF6 RAPSN NSD1 TRIM64B KMT2D MIB1

4.90e-03305966SM00184
PathwayREACTOME_TRAIL_SIGNALING

TNFRSF10D TNFRSF10C TNFRSF10A

7.95e-068753MM15449
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_DEATH_RECEPTORS_AND_LIGANDS

TNFRSF10D TNFRSF10C TNFRSF10A

3.07e-0512753M27631
PathwayREACTOME_REGULATION_BY_C_FLIP

TNFRSF10D TNFRSF10C TNFRSF10A

3.98e-0513753MM14947
PathwayWP_MYD88_DISTINCT_INPUTOUTPUT_PATHWAY

TRAF6 TLR6 TLR1

1.11e-0418753M39478
PathwayREACTOME_CASPASE_ACTIVATION_VIA_DEATH_RECEPTORS_IN_THE_PRESENCE_OF_LIGAND

TNFRSF10D TNFRSF10C TNFRSF10A

1.32e-0419753MM14555
PathwayREACTOME_CASPASE_ACTIVATION_VIA_EXTRINSIC_APOPTOTIC_SIGNALLING_PATHWAY

TNFRSF10D TNFRSF10C TNFRSF10A

2.37e-0423753MM15176
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

2.76e-045752M47667
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

4.13e-046752M47668
PathwayPID_TRAIL_PATHWAY

TNFRSF10D TNFRSF10C TNFRSF10A

4.31e-0428753M79
PathwayPID_WNT_SIGNALING_PATHWAY

WNT1 FZD8 FZD5

4.31e-0428753M77
PathwayWP_TOLLLIKE_RECEPTOR_SIGNALING_RELATED_TO_MYD88

TRAF6 TLR6 TLR1

5.84e-0431753M39573
Pubmed

Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut.

TRAF6 TNFRSF10D TNFRSF10C TNFRSF10A TLR6 TLR1 LTBR

1.45e-0895103720568250
Pubmed

Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivation.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103331473246
Pubmed

Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103330423122
Pubmed

TRAIL receptor deficiency sensitizes mice to dextran sodium sulphate-induced colitis and colitis-associated carcinogenesis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103324117005
Pubmed

Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103314769851
Pubmed

TNFRSF10A downregulation induces retinal pigment epithelium degeneration during the pathogenesis of age-related macular degeneration and central serous chorioretinopathy.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103335103281
Pubmed

Membrane expression of TRAIL receptors DR4, DR5, DcR1 and DcR2 in the normal endometrium, atypical endometrial hyperplasia and endometrioid adenocarcinoma: a tissue microarray study.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103323584885
Pubmed

The murine TRAIL receptor signals caspase-independent cell death through ceramide.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103317026999
Pubmed

Membrane expression of the death ligand trail receptors DR4 and DR5 in the normal endometrium, endometrial atypical hyperplasia and endometrioid endometrial cancer.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103323815209
Pubmed

Blockade of TRAIL pathway ameliorates HBV-induced hepatocyte apoptosis in an acute hepatitis model.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103317126290
Pubmed

TRAIL-R Deficient Mice Are Protected from Neurotoxic Effects of Amyloid-β.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103336232931
Pubmed

TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103324695582
Pubmed

Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103326791792
Pubmed

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103318079962
Pubmed

TRAIL-R as a negative regulator of innate immune cell responses.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103315589175
Pubmed

Induction of death receptor 5 expression in tumor vasculature by perifosine restores the vascular disruption activity of TRAIL-expressing CD34(+) cells.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103323605004
Pubmed

Death receptor 5 is required for intestinal stem cell activity during intestinal epithelial renewal at homoeostasis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103338199990
Pubmed

TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103315921376
Pubmed

T Cell-Specific Deletion of TRAIL Receptor Reveals Its Critical Role for Regulating Pathologic T Cell Activation and Disease Induction in Experimental Autoimmune Encephalomyelitis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103335264458
Pubmed

The transmembrane domains of TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 co-regulate apoptotic signaling capacity.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103322916132
Pubmed

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103323676461
Pubmed

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103324994655
Pubmed

DR5 knockout mice are compromised in radiation-induced apoptosis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.01e-074103315713653
Pubmed

The TNF and TNF receptor superfamilies: integrating mammalian biology.

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

1.10e-0739103511239407
Pubmed

Functional roles of tumor necrosis factor-related apoptosis-inducing ligand-DR5 interaction in B16F10 cells by activating the nuclear factor-κB pathway to induce metastatic potential.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103323347256
Pubmed

TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103323071253
Pubmed

TRAIL-expressing CD8+ T cells mediate tolerance following soluble peptide-induced peripheral T cell deletion.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103320807702
Pubmed

TRAIL, DR4 and DR5 are upregulated in kidneys from patients with lupus nephritis and exert proliferative and proinflammatory effects.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103319349211
Pubmed

TNFRSF10B is involved in motor dysfunction in Parkinson's disease by regulating exosomal α-synuclein secretion from microglia.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103336791922
Pubmed

Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103315173180
Pubmed

TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103321225479
Pubmed

In chronic pancreatitis, widespread emergence of TRAIL receptors in epithelia coincides with neoexpression of TRAIL by pancreatic stellate cells of early fibrotic areas.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103312808117
Pubmed

Systemic immunological tolerance to ocular antigens is mediated by TRAIL-expressing CD8+ T cells.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103321169546
Pubmed

TRAIL-Mediated Suppression of T Cell Receptor Signaling Inhibits T Cell Activation and Inflammation in Experimental Autoimmune Encephalomyelitis.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103329403497
Pubmed

Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103311844843
Pubmed

TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103318079967
Pubmed

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103310862756
Pubmed

TRAIL/DR5 signaling promotes macrophage foam cell formation by modulating scavenger receptor expression.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103324466325
Pubmed

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103330850660
Pubmed

Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103310383128
Pubmed

TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell destruction.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103312488957
Pubmed

Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103317051329
Pubmed

TRAIL induces proliferation in rodent pancreatic beta cells via AKT activation.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103333875613
Pubmed

Expression of TRAIL and its receptors DR5 and DcR2 in orthodontic tooth movement.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103323430714
Pubmed

TRAIL and KILLER are expressed and induce apoptosis in the murine preimplantation embryo.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103315128592
Pubmed

Following a TRAIL: update on a ligand and its five receptors.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103315538968
Pubmed

Hypoxia-induced apoptosis of mouse spermatocytes is mediated by HIF-1α through a death receptor pathway and a mitochondrial pathway.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103328444885
Pubmed

Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103322789540
Pubmed

Signaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103317041756
Pubmed

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103319226377
Pubmed

CD8 T cells utilize TRAIL to control influenza virus infection.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103318802095
Pubmed

Death receptor 5 signaling promotes hepatocyte lipoapoptosis.

TNFRSF10D TNFRSF10C TNFRSF10A

2.51e-075103321941003
Pubmed

LDL-receptor-related proteins in Wnt signal transduction.

WNT1 FZD8 FZD5

2.51e-075103311029007
Pubmed

A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103337460623
Pubmed

TRAIL/DR5 plays a critical role in NK cell-mediated negative regulation of dendritic cell cross-priming of T cells.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103321832159
Pubmed

Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103318006832
Pubmed

Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103328055006
Pubmed

Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103316174727
Pubmed

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103316046522
Pubmed

Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103315990565
Pubmed

No requirement for TRAIL in intrathymic negative selection.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103318192669
Pubmed

Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103315514675
Pubmed

Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.

TNFRSF10D TNFRSF10C TNFRSF10A

5.01e-076103318667695
Pubmed

Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4

5.09e-0722103415301860
Pubmed

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2.

TNFRSF10D TNFRSF10C TNFRSF10A

8.75e-077103334223817
Pubmed

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

WNT1 FZD8 FZD5

8.75e-07710339192640
Pubmed

Death receptor 5 and neuroproliferation.

TNFRSF10D TNFRSF10C TNFRSF10A

8.75e-077103321938487
Pubmed

Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription.

WNT1 FZD8 FZD5

8.75e-077103311265645
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GPRIN3 GRIN2A GRIN2B

8.75e-077103322833210
Pubmed

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.

TRAF6 TNFRSF10D TNFRSF10C TNFRSF10A TLR6 TLR1 ZFYVE21 LTBR

1.23e-06263103819773279
Pubmed

Opposing role of tumor necrosis factor receptor 1 signaling in T cell-mediated hepatitis and bacterial infection in mice.

TNFRSF10D TNFRSF10C TNFRSF10A

1.40e-068103326991125
Pubmed

Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.

TNFRSF10D TNFRSF10C TNFRSF10A

1.40e-068103325843002
Pubmed

Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

TNFRSF10D TNFRSF10C TNFRSF10A

1.40e-068103315044455
Pubmed

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.

TNFRSF10D TNFRSF10C TNFRSF10A

1.40e-068103326609054
Pubmed

IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals.

TNFRSF10D TNFRSF10C TNFRSF10A

2.09e-069103317617585
Pubmed

Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.

TNFRSF10D TNFRSF10C TNFRSF10A

2.98e-0610103324971483
Pubmed

Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL resistant.

TNFRSF10D TNFRSF10C TNFRSF10A

2.98e-0610103321768400
Pubmed

The plasticity of regulatory T cell function.

TNFRSF10D TNFRSF10C TNFRSF10A

2.98e-0610103322013112
Pubmed

RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.

TNFRSF10D TNFRSF10C TNFRSF10A

4.09e-0611103330988397
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

WNT1 FZD8 FZD5

4.09e-0611103317582687
Pubmed

Common genetic variants in candidate genes and risk of familial lymphoid malignancies.

TRAF6 TNFRSF10D TNFRSF10C TNFRSF10A TLR6 TLR1

4.85e-06145103619573080
Pubmed

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.

TNFRSF10D TNFRSF10C TNFRSF10A

5.44e-0612103330254289
Pubmed

Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE.

TRAF6 TLR6 TLR1

5.44e-0612103319254290
Pubmed

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.

TNFRSF10D TNFRSF10C TNFRSF10A

5.44e-0612103329436413
Pubmed

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.

TNFRSF10D TNFRSF10C TNFRSF10A

7.06e-0613103326982364
Pubmed

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

TLR6 TLR1

8.69e-062103222315281
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

8.69e-062103225131300
Pubmed

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

TLR6 TLR1

8.69e-062103218036178
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

8.69e-062103237657442
Pubmed

TRAIL induces death of human oligodendrocytes isolated from adult brain.

TNFRSF10D TNFRSF10C

8.69e-062103212390973
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

8.69e-062103238813758
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

8.69e-062103238731978
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

8.69e-062103220921396
Pubmed

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

TLR6 TLR1

8.69e-062103224445834
Pubmed

A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse.

TNFRSF10C TNFRSF10A

8.69e-062103222595876
Pubmed

[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].

TLR6 TLR1

8.69e-062103226470427
Pubmed

Spinal NR2B phosphorylation at Tyr1472 regulates IRE(-)DMT1-mediated iron accumulation and spine morphogenesis via kalirin-7 in tibial fracture-associated postoperative pain after orthopedic surgery in female mice.

SLC11A2 GRIN2B

8.69e-062103233443215
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

8.69e-062103230269991
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

8.69e-062103227199241
Pubmed

Membrane expression of trail receptors DcR1 and DcR2 in the normal endometrium, endometrial atypical hyperplasia and endometrioid endometrial cancer.

TNFRSF10D TNFRSF10C

8.69e-062103224649804
InteractionIGFL3 interactions

PCSK5 LRP12 LAMA3 VWDE PXDN LRP2

1.64e-0675976int:IGFL3
InteractionLRP6 interactions

TRAF6 WNT1 GRIN2A FZD8 FZD5 TLR1 CCL1

2.83e-06128977int:LRP6
CytobandEnsembl 112 genes in cytogenetic band chr8p21

TNFRSF10D TNFRSF10C TNFRSF10A EGR3

2.52e-041351034chr8p21
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF10D TNFRSF10C TNFRSF10A TNFRSF4 LTBR

1.63e-0729805782
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PLEKHF1 WDFY2 MTMR4 ZFYVE21 FGD1

2.32e-073180581
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS5 ADAMTS16 ADAMTS20

7.68e-051980350
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

4.00e-0478021201
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD1 KMT2D EHMT2

4.52e-0434803487
GeneFamilyCD molecules|Toll like receptors

TLR6 TLR1

8.50e-0410802948
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD8 FZD5

1.04e-0311802286
GeneFamilyLow density lipoprotein receptors

LRP12 LRP2

1.46e-0313802634
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TNFRSF10D TNFRSF10C TNFRSF10A TLR6 TNFRSF4 PTPRJ TLR1

1.79e-03394807471
GeneFamilyAminoacyl tRNA synthetases, Class I

EPRS1 LARS2

3.15e-0319802131
GeneFamilyRegulators of G-protein signaling

RGS16 RGS6

3.84e-0321802720
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC18 ZDHHC9

5.01e-032480276
GeneFamilyArfGAPs

GIT1 ACAP2

9.34e-0333802395
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN GPRIN3 VWDE RGS16 TNFRSF4 CCL1

3.01e-0617210364d04df9776394ea156ed5822f92ae74fdefbaa3d
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN GPRIN3 VWDE RGS16 TNFRSF4 CCL1

3.01e-0617210363acf35b774ebc0f9e96299d0bd3e9d03bbf6b90c
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAPSN GPRIN3 VWDE RGS16 TNFRSF4 CCL1

3.32e-0617510363bdccb4037053795d62ab5b6fcc09cdd406f9b50
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAPSN GPRIN3 VWDE RGS16 TNFRSF4 CCL1

3.32e-061751036770546ddaa49ee482c4c7577ab76efbc6c304a29
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS5 TLR6 PXDN TLR1 ADAMTS16 SPOCD1

3.79e-061791036cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA3 VWDE NTN4 MFSD2A HPN LRP2

4.72e-061861036bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RGS16 NTN4 MFSD2A FZD5 HPN LRP2

7.15e-062001036acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

RGS16 NTN4 MFSD2A FZD5 HPN LRP2

7.15e-062001036ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RGS16 NTN4 MFSD2A FZD5 HPN LRP2

7.15e-062001036eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

WNT1 LHFPL1 CCL1 OTOG

3.24e-05781034564ea2c113058df595c3b69827cf9a72380b48fc
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

WNT1 LHFPL1 CCL1 OTOG

3.24e-05781034dfe16ac0b10dce7ecf4b3a0b4e1013ac58cb9fc1
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

WNT1 LHFPL1 CCL1 OTOG

3.24e-057810346aa418ea30dfa7df2fc08cac5b31e3a654aaa7f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS5 ITPRID1 RGS16 GALNT17 PTPRJ

3.97e-05164103583141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRIN3 LHFPL1 RGS16 TNFRSF4 FZD5

4.46e-05168103504a7810f95196a21325356b42084f96c11af5964
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF TLR6 RNASE6 FZD5 TLR1

4.58e-05169103515a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARS2 KCNH4 TNFRSF4 LRP2 DNAH6

4.58e-05169103512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFAP47 RAPSN VWDE RGS16 CRB1

5.71e-0517710356f3b254e56e722cc23495b49e99a4abce0243cb3
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

FBXO38 WDR11 EHMT2 POLR1B SPOCD1

5.86e-051781035536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPRIN3 NTN4 GALNT17 RGS6 DNAH6

6.02e-051791035c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC11A2 LAMA3 NTN4 MFSD2A HPN

6.02e-051791035fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO PLEKHF1 ADAMTS5 TNFRSF4 GALNT17

6.18e-051801035f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPRIN3 NTN4 GALNT17 RGS6 DNAH6

6.18e-0518010358923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LINC02881 GRIN2B RGS16 EGR3 CCL1

6.18e-051801035f103e161e966c257eac97e1b30a461c4ed9cafc2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TLR6 PLEKHH3 PNPO TNFRSF4 LTBR

6.34e-051811035c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZDHHC18 TNFRSF10C PLEKHH3 PTPRJ EGR3

6.51e-051821035dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADAMTS16 LRP2 ADAMTS20 OTOG

6.86e-0518410352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGS6 PXDN EGR3 ADAMTS16 DNAH6

6.86e-051841035ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADAMTS16 LRP2 ADAMTS20 OTOG

6.86e-051841035ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B ADAMTS16 LRP2 ADAMTS20 OTOG

6.86e-0518410352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NOG ADAMTS5 CACNA1G FRMPD3

7.22e-051861035b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NOG ADAMTS5 CACNA1G FRMPD3

7.22e-051861035cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA3 VWDE MFSD2A HPN LRP2

7.40e-051871035db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 RREB1 HPN LRP2 RASSF4

7.40e-0518710353ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 NOG ADAMTS5 CACNA1G FRMPD3

7.40e-0518710358bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 NOG ADAMTS5 CACNA1G FRMPD3

7.40e-0518710353cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

RGS16 MFSD2A ZDHHC9 HPN LRP2

7.59e-0518810355f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZDHHC18 TNFRSF10C TLR6 EGR3 TLR1

7.59e-051881035aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZDHHC18 TNFRSF10C TLR6 EGR3 TLR1

7.59e-05188103504814b78da936a51a497e23060d19ca0d619e250
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CCDC125 CFAP47 LAMA3 VWDE LRP2

7.78e-0518910357659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LINC00473 SLC11A2 NEXMIF GRIN2B ADAMTS16

7.98e-051901035b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MPO ATG2B KMT2D WDR11 POLR1B

7.98e-0519010353f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA3 GRIN2A GRIN2B ADAMTS5 LRP2

8.18e-0519110354c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 NOG GRIN2B NTN4 RGS6

8.38e-05192103593903576dddd8227328e4ced75aa7625eedb9baf
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MPO ATG2B KMT2D WDR11 POLR1B

8.38e-051921035c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 GPRIN3 CRB1 NTN4 ADAMTS20

8.59e-051931035d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

8.80e-051941035c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

8.80e-051941035c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

9.01e-051951035f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS16 NTN4 MFSD2A FZD5 LRP2

9.01e-051951035d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

9.23e-0519610350a34a0009f479384f1994c6f977f942699a132c8
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

9.46e-05197103522b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A2 MFSD2A RNASE6 TLR1 RASSF4

9.46e-05197103561bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

9.46e-0519710356852a8ec1397811bbdd1fc625c52ed4fa75a931e
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LAMA3 NTN4 MFSD2A HPN LRP2

9.46e-0519710352f91b3870a7058168093a143110954c07588cfe9
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS16 MFSD2A ZDHHC9 HPN LRP2

9.46e-051971035d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RGS16 MFSD2A ZDHHC9 FZD5 LRP2

9.69e-05198103519eefd05573fbaed654af52bf0f8a26092b8b229
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC11A2 LAMA3 PGM3 NTN4 HPN

9.69e-051981035285f729140b1df029c24f6ca1d2438470ac51794
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_only / Treatment groups by lineage, cell group, cell type

HIRA MFSD2A MTMR4 TLR1 RASSF4

9.69e-05198103553c22e81e530d6fc272d4a45c8d1bf125feb254d
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RGS16 MFSD2A ZDHHC9 FZD5 HPN

9.69e-051981035de5748c2b66ecc432974cf095ecd241369579f7c
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPRIN3 TLR6 RNASE6 RASSF4 RFPL3S

9.92e-051991035514dbf128b6832b1cbd65be023d4fe02400e8dec
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PNPO TNFRSF4 MFSD2A TLR1 RASSF4

9.92e-0519910356dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCellCOVID-19-COVID-19_Mild-Myeloid-Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

ZDHHC18 TNFRSF10C TLR6 EGR3 TLR1

9.92e-0519910359f6b6731186ef399f952a75879eba66fd8ed3494
ToppCelldistal-2-Epithelial-Alveolar_Epithelial_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RGS16 MFSD2A FZD5 HPN LRP2

9.92e-05199103521b44031bc5182ee23ba5e206042b2e5e4ee0c3c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PPRC1 TNFRSF10D RGS16 DNAH6 MOV10

1.02e-0420010354db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PPRC1 TNFRSF10D RGS16 DNAH6 MOV10

1.02e-042001035d46a19274c2836ce7494790ce513764dedcadc79
ToppCellKidney-Fibroblasts|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

TKTL1 ADAMTS5 ITPRID1 ZNF526 TLR1

1.02e-0420010352c265ad8314a21bce50ac21b16da2fea125366ea
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PLEKHF1 PLEKHH3 MIB1 RASSF4

1.04e-0410510348f31edf4183587f5b53941475453c5aa49f10bbd
Diseaseosteoarthritis (biomarker_via_orthology)

ADAMTS5 TNFRSF10D TNFRSF10C TNFRSF10A

6.56e-0721984DOID:8398 (biomarker_via_orthology)
DiseaseProfound Mental Retardation

NSD1 GRIN2B MFSD2A ZNF526 CACNA1G TAF2

7.23e-06139986C0020796
DiseaseMental Retardation, Psychosocial

NSD1 GRIN2B MFSD2A ZNF526 CACNA1G TAF2

7.23e-06139986C0025363
DiseaseMental deficiency

NSD1 GRIN2B MFSD2A ZNF526 CACNA1G TAF2

7.23e-06139986C0917816
DiseaseIntellectual Disability

NSD1 GRIN2B PGM3 MFSD2A ZNF526 ZDHHC9 LRP2 CACNA1G TAF2

1.85e-05447989C3714756
DiseaseCluttering

GRIN2A MFSD2A

3.27e-053982C0009090
DiseaseDyslalia

GRIN2A MFSD2A

3.27e-053982C3495145
DiseaseAprosodia

GRIN2A MFSD2A

3.27e-053982C0233726
DiseaseRhinolalia

GRIN2A MFSD2A

3.27e-053982C0751513
DiseaseDysglossia

GRIN2A MFSD2A

3.27e-053982C0751512
DiseaseVerbal Fluency Disorders

GRIN2A MFSD2A

3.27e-053982C0751514
Diseaseneck circumference

NOG GALNT17 ADAMTS20

3.31e-0519983EFO_0011043
DiseaseHuntington's disease (is_implicated_in)

NOG GRIN2A GRIN2B

5.99e-0523983DOID:12858 (is_implicated_in)
DiseaseSpeech Disorders

GRIN2A MFSD2A

6.52e-054982C0037822
Diseaseneutrophil count, basophil count

CCDC125 MPO RAPSN TNFRSF10C RREB1 PTPRJ

1.05e-04224986EFO_0004833, EFO_0005090
Diseasecone-rod dystrophy (is_implicated_in)

PDE6C CRB1

1.08e-045982DOID:0050572 (is_implicated_in)
Diseasetuberculosis (is_implicated_in)

TLR6 TLR1 CCL1

1.10e-0428983DOID:399 (is_implicated_in)
Disease1-stearoyl-GPC (18:0) measurement

RAPSN MFSD2A

1.62e-046982EFO_0800217
Diseasecolon cancer (biomarker_via_orthology)

TNFRSF10D TNFRSF10C TNFRSF10A

2.98e-0439983DOID:219 (biomarker_via_orthology)
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

3.02e-048982DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

3.02e-048982DOID:1561 (biomarker_via_orthology)
Diseaseaspergillosis (is_implicated_in)

TLR6 TLR1

3.02e-048982DOID:13564 (is_implicated_in)
Disease22q11 partial monosomy syndrome

RREB1 HIRA

3.87e-049982C3266101
DiseaseAsymmetric crying face association

RREB1 HIRA

4.83e-0410982C0431406
Diseasephosphatidylethanolamine ether measurement

RAPSN GALNT17

4.83e-0410982EFO_0010229
Disease22q11 Deletion Syndrome

RREB1 HIRA

4.83e-0410982C2936346
DiseaseEpilepsy

NEXMIF GRIN2A GRIN2B ZDHHC9

4.87e-04109984C0014544
Diseasecomplement factor H-related protein 4 measurement

CRB1 NTN4 RGS6

5.86e-0449983EFO_0600091
DiseaseMicrophthalmos

CRB1 KMT2D

5.89e-0411982C0026010
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

5.89e-0411982DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

5.89e-0411982DOID:8725 (is_marker_for)
Diseaseneutrophil count, eosinophil count

CCDC125 MPO RAPSN TNFRSF10C PTPRJ

7.37e-04213985EFO_0004833, EFO_0004842
Diseasemale infertility (implicated_via_orthology)

CFAP47 ADAMTS16

8.32e-0413982DOID:12336 (implicated_via_orthology)
Diseasemyeloid white cell count

CCDC125 MPO ZDHHC18 RAPSN TNFRSF10C RREB1 GALNT17 PTPRJ POLR1B LTBR

1.12e-039379810EFO_0007988
DiseaseDiGeorge Syndrome

RREB1 HIRA

1.27e-0316982C0012236
DiseaseCONOTRUNCAL ANOMALY FACE SYNDROME

RREB1 HIRA

1.27e-0316982C0795907
Diseasephosphatidylcholine 32:2 measurement

RAPSN MIB1

1.27e-0316982EFO_0010374
DiseaseShprintzen syndrome

RREB1 HIRA

1.27e-0316982C0220704
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR6 TLR1

1.44e-0317982DOID:8677 (biomarker_via_orthology)
Diseaseintraocular pressure measurement

PCSK5 LRP12 RAPSN KLHL38 PTPRJ LMX1B ADAMTS20

1.56e-03509987EFO_0004695
Diseasegranulocyte count

CCDC125 MPO RAPSN TNFRSF10C PTPRJ

1.61e-03254985EFO_0007987
Diseaseanorexia nervosa

CRB1 WDR11 LRP2

1.66e-0370983MONDO_0005351
Diseasehepatitis B virus infection

GRIN2A EHMT2

1.80e-0319982EFO_0004197
DiseaseOvarian Failure, Premature

NOG NR5A1

2.20e-0321982C0085215
Diseasemyeloperoxidase (MPO)-DNA complex measurement

MPO LARS2

2.42e-0322982EFO_0011039
DiseaseAttention Deficit Disorder

GIT1 FGD1

2.42e-0322982C0041671
DiseaseMinimal Brain Dysfunction

GIT1 FGD1

2.42e-0322982C1321905
Diseasenephrosis (biomarker_via_orthology)

LRP2 CCL1

2.42e-0322982DOID:2527 (biomarker_via_orthology)
DiseaseEpilepsy, Cryptogenic

NEXMIF GRIN2A GRIN2B

2.60e-0382983C0086237
DiseaseAwakening Epilepsy

NEXMIF GRIN2A GRIN2B

2.60e-0382983C0751111
DiseaseAura

NEXMIF GRIN2A GRIN2B

2.60e-0382983C0236018
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR4 FGD1

2.87e-0324982DOID:10595 (implicated_via_orthology)
DiseaseAttention deficit hyperactivity disorder

GIT1 FGD1

2.87e-0324982C1263846
Diseaselung squamous cell carcinoma (is_implicated_in)

KMT2D PTPRJ

2.87e-0324982DOID:3907 (is_implicated_in)
DiseaseKidney Diseases

MPO PCSK5 LRP2

3.18e-0388983C0022658

Protein segments in the cluster

PeptideGeneStartEntry
VDSKSMQVPFSRCCF

CCL1

21

P22362
PQGMEIKSNERCCSF

PGM3

261

O95394
CTGKRAIYRSCSLMP

ADAMTS5

606

Q9UNA0
AFDMIGQRSRSSKCP

GIPC3

196

Q8TF64
MSRKGPRAEVCADCS

GIT1

1

Q9Y2X7
TERGFEELPLCSCRM

EHMT2

416

Q96KQ7
RRFCFEVVSPTKSCM

ACAP2

326

Q15057
SGRSPQECCLRVSLM

ATG2B

1691

Q96BY7
PISGMCSKYRSCTIN

ADAMTS16

406

Q8TE57
VGRRMKFRSCNTDSC

ADAMTS20

596

P59510
MPRGKFICNECRTGI

NSD1

1576

Q96L73
VSASKGRLMRCVRCP

NSD1

1651

Q96L73
TRSCPNCRRSSMKPG

RAPSN

396

Q13702
SDASCMSQRRPKCRA

RASSF4

141

Q9H2L5
VPGCVNTTEMDIRKC

RGS6

206

P49758
CCPQGFLRSGTKRVM

KIRREL3-AS3

191

Q8N7Y1
EKSCGACLREETPRM

ELOA2

251

Q8IYF1
VSCGKMAAPTRNTCT

PTPRJ

796

Q12913
TMCQKEEFPCSRNGV

LRP12

411

Q9Y561
CNCSRRGTIEAAMPE

LAMA3

1356

Q16787
DMACAKTTTRGECPR

ITPRID1

521

Q6ZRS4
CPMTRIFDDGRCVSN

PCSK5

906

Q92824
TCPEQDKYRTITGMC

MPO

166

P05164
CSMFLCRSRNGIPEV

PDE6C

96

P51160
GRTEVMQKTCSCRFL

KCNH4

56

Q9UQ05
VLKGMFVPSCSGCRT

SLC11A2

236

P49281
SCRPGYKLMSDKRTC

LRP2

3136

P98164
SQMGKPVSFSTFRRC

LHFPL1

36

Q86WI0
MCLATCTRDGKPSAR

PNPO

81

Q9NVS9
MRSPEGRQKAFSTCA

OR5B12

226

Q96R08
CRMNRKQYIRSCPGT

MEIOSIN

551

C9JSJ3
MAQKEGGRTVPCCSR

HPN

1

P05981
GCCSKRPNSKQMRAT

MTMR4

931

Q9NYA4
RRVPFIMCCGGKSSE

MIB1

906

Q86YT6
RGCSQPERVKFTLNM

MFSD2A

471

Q8NA29
CISLRTFVMRNCAGP

FBXO38

231

Q6PIJ6
RSVCERAKAGCSPLM

FZD5

106

Q13467
GCQCRAPMVSVSSER

FZD8

231

Q9H461
LCMSPVGEAFRSRCR

DNAH6

2576

Q9C0G6
RSRCRMFPSLVNCCT

DNAH6

2586

Q9C0G6
GNPCSCARMAASTRK

CCDC125

286

Q86Z20
CSQPRENGMRSCRSV

CACNA1G

271

O43497
RRAPGCAGRCITMKN

LINC00473

71

A8K010
SFSCAKRALMRRPGC

CPHXL2

121

A0A1W2PPK0
GPGMSREQRRSCDCK

FRMPD3

1321

Q5JV73
GHKPFQCRICMRSFS

EGR3

301

Q06889
RTPAMIGCSFVVNRK

GALNT17

321

Q6IS24
ACEKRMLSVFSTCGR

HIRA

751

P54198
EFQTELKCMCRPGFT

CRB1

1276

P82279
EMRSCKPLTRESGCS

GPRIN3

231

Q6ZVF9
FKPCFMGERSEIQCI

CFAP47

421

Q6ZTR5
SMRCYRKACRSASPS

PPRC1

1401

Q5VV67
SCLMAPSVSCRKRYS

LGSN

356

Q5TDP6
GSCFSKRSCSVPEGM

NOG

176

Q13253
ATTDCSPCLRMVSNR

OTOG

2301

Q6ZRI0
SPCLRMVSNRTFSAC

OTOG

2306

Q6ZRI0
PDKATDICMRCTQTR

PLEKHF1

151

Q96S99
PFCRFQKCLTVGMRL

NR5A1

66

Q13285
SNNGCMRDPTLYRCK

EPRS1

346

P07814
LTCMSCTFRPGGAVR

PLEKHH3

336

Q7Z736
CPRCKGAAKRETDTM

LARS2

506

Q15031
VSSRCEKACNPRMGN

NTN4

26

Q9HB63
MPSKFSCRQLREAGQ

MOV10

1

Q9HCE1
SLFTRMFCCKSCPNI

TAF2

721

Q6P1X5
QPSRTCLGCFMESKD

NEXMIF

141

Q5QGS0
CMRCQEPFNSITKRR

FGD1

736

P98174
MTDCRLTSGKYPQCR

RNASE6

101

Q93091
MRSIKAGDNPFQCTC

TLR1

516

Q15399
SFFCRMKCNRPSVKV

ARNTL

246

O00327
SKNSSRLGGRPCMCT

C10orf95

36

Q9H7T3
VGSSCKRPTVCMGRQ

LINC02881

56

B7Z368
FQDKNSPEMCRTCRT

TNFRSF10D

146

Q9UBN6
RTCRTGCPRGMVKVS

TNFRSF10D

156

Q9UBN6
KRRCTRFCSASLEMP

TP53TG5

236

Q9Y2B4
TGRRFQKSICDPTCM

VWDE

1481

Q8N2E2
KLPGRNTFCCDGRVM

ZDHHC9

16

Q9Y397
CSCMSFNPETRRLSI

WDFY2

71

Q96P53
MRSHTGERPYKCQTC

RREB1

1531

Q92766
SNLSARSCRFCVMSP

RFPL3S

6

P0C7P2
SRACSGPFMEQRRSK

SPOCD1

406

Q6ZMY3
PCTFSTFGCHEKMQR

TRAF6

241

Q9Y4K3
SGARCMFFVRSSPVC

PXDN

871

Q92626
FRNENSPEMCRKCSR

TNFRSF10C

116

O14798
MCRTLAAFPTTCLER

RGS16

1

O15492
KPGTFRNDNSAEMCR

TNFRSF10A

191

O00220
MRSIKAGDNPFQCTC

TLR6

521

Q9Y2C9
CRPGNGMVSRCSRSQ

TNFRSF4

46

P43489
TSCCERGFKAMNRIR

ZNF862

1036

O60290
CTSKRKTQCRCQPGM

LTBR

116

P36941
GRTTVFSEMRQECKC

WNT1

206

P04628
TRGPCPDMQSRCQTK

ZNF790

71

Q6PG37
RCCSQKVPLRRMCFV

ZFYVE21

76

Q9BQ24
PLHRCRCGKTFSNMT

ZNF526

386

Q8TF50
THSGEKPFMCRECGR

ZNF875

546

P10072
RVTKTVRPFSMVCCP

WDR11

351

Q9BZH6
RRESPTMTEFLCKEC

AGPAT5

241

Q9NUQ2
SGKFKCVCITMRVPR

POLR1B

861

Q9H9Y6
RGERPFTCMECGKSF

ZNF777

541

Q9ULD5
RALEMCPSCFQKERS

TTC1

141

Q99614
GRAPMRCPSCRKTSE

TRIM64B

46

A6NI03
ANAKGMCFIRTTRPE

TKTL1

436

P51854
TCKMFRPPRTSHCSV

ZDHHC18

196

Q9NUE0
AIKCTMCRAQRPSGT

ZRANB1

21

Q9UGI0
KRQMFSLCGTTVPDC

KLHL38

256

Q2WGJ6
QRTGATSSCNRMRCP

KMT2D

5096

O14686
ERCFPRGQTDCAKML

LMX1B

11

O60663
RSPFKCDACLRMGNL

GRIN2A

1231

Q12879
SGTCMRNTVPCQKRI

GRIN2B

426

Q13224