Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LTBP2 CHADL ECM1 SSPOP LTBP4 TNC	3.16e-07	188	30	6	GO:0005201
GeneOntologyMolecularFunction	growth factor binding	KAZALD1 LTBP2 HTRA1 LTBP4	8.38e-05	156	30	4	GO:0019838
GeneOntologyMolecularFunction	structural molecule activity	LAMC3 LTBP2 CHADL ECM1 SSPOP LTBP4 TNC	2.84e-04	891	30	7	GO:0005198
GeneOntologyMolecularFunction	protein-hormone receptor activity	LGR4 LGR5	4.95e-04	22	30	2	GO:0016500
GeneOntologyMolecularFunction	fibronectin binding	FSTL3 TNC	1.48e-03	38	30	2	GO:0001968
GeneOntologyBiologicalProcess	regulation of BMP signaling pathway	KCP VWC2 HTRA1 FSTL3 ZNF423	1.42e-06	131	31	5	GO:0030510
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	KCP VWC2 LTBP2 HTRA1 FSTL3 LTBP4 ZNF423	3.49e-06	445	31	7	GO:0141091
GeneOntologyBiologicalProcess	cell surface receptor protein serine/threonine kinase signaling pathway	KCP VWC2 LTBP2 HTRA1 FSTL3 LTBP4 ZNF423	5.89e-06	482	31	7	GO:0007178
GeneOntologyBiologicalProcess	BMP signaling pathway	KCP VWC2 HTRA1 FSTL3 ZNF423	1.05e-05	197	31	5	GO:0030509
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	KCP VWC2 HTRA1 FSTL3 LTBP4 ZNF423	1.12e-05	347	31	6	GO:0090092
GeneOntologyBiologicalProcess	epithelial cell proliferation involved in renal tubule morphogenesis	LGR4 LGR5	1.31e-05	4	31	2	GO:2001013
GeneOntologyBiologicalProcess	response to BMP	KCP VWC2 HTRA1 FSTL3 ZNF423	1.60e-05	215	31	5	GO:0071772
GeneOntologyBiologicalProcess	cellular response to BMP stimulus	KCP VWC2 HTRA1 FSTL3 ZNF423	1.60e-05	215	31	5	GO:0071773
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	LGR4 ADRB3 LGR5	1.78e-05	34	31	3	GO:0007190
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	LGR4 ADRB3 LGR5	2.92e-05	40	31	3	GO:0045762
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	KCP VWC2 HTRA1 FSTL3 LTBP4 ZNF423	2.95e-05	412	31	6	GO:0090287
GeneOntologyBiologicalProcess	response to growth factor	KCP VWC2 LTBP2 HTRA1 FSTL3 LTBP4 TNC ZNF423	3.58e-05	883	31	8	GO:0070848
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	LGR4 ADRB3 LGR5	5.08e-05	48	31	3	GO:0031281
GeneOntologyBiologicalProcess	positive regulation of lyase activity	LGR4 ADRB3 LGR5	5.40e-05	49	31	3	GO:0051349
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	LGR4 ADRB3 LGR5	9.44e-05	59	31	3	GO:0045761
GeneOntologyBiologicalProcess	regulation of cyclase activity	LGR4 ADRB3 LGR5	1.51e-04	69	31	3	GO:0031279
GeneOntologyBiologicalProcess	ossification	LGR4 KAZALD1 FSTL3 ECM1 EGR2 TNC	1.64e-04	562	31	6	GO:0001503
GeneOntologyBiologicalProcess	regulation of lyase activity	LGR4 ADRB3 LGR5	1.78e-04	73	31	3	GO:0051339
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	KCP VWC2 LTBP2 HTRA1 FSTL3 LTBP4 ZNF423	2.17e-04	850	31	7	GO:0071363
GeneOntologyBiologicalProcess	negative regulation of BMP signaling pathway	VWC2 HTRA1 FSTL3	2.34e-04	80	31	3	GO:0030514
GeneOntologyBiologicalProcess	positive regulation of interferon-alpha production	TRIM65 TLR9	9.26e-04	30	31	2	GO:0032727
GeneOntologyBiologicalProcess	regulation of interferon-alpha production	TRIM65 TLR9	1.41e-03	37	31	2	GO:0032647
GeneOntologyBiologicalProcess	negative regulation of cellular response to growth factor stimulus	VWC2 HTRA1 FSTL3	1.46e-03	150	31	3	GO:0090288
GeneOntologyBiologicalProcess	regulation of cold-induced thermogenesis	LGR4 ADRB3 ZNF423	1.52e-03	152	31	3	GO:0120161
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	KCP VWC2 LTBP2 HTRA1 FSTL3 LTBP4 ZNF423	1.59e-03	1186	31	7	GO:0007167
GeneOntologyBiologicalProcess	cold-induced thermogenesis	LGR4 ADRB3 ZNF423	1.63e-03	156	31	3	GO:0106106
GeneOntologyBiologicalProcess	interferon-alpha production	TRIM65 TLR9	1.65e-03	40	31	2	GO:0032607
GeneOntologyBiologicalProcess	positive regulation of BMP signaling pathway	KCP ZNF423	1.81e-03	42	31	2	GO:0030513
GeneOntologyCellularComponent	extracellular matrix	TRIL VWC2 LAMB4 LAMC3 KAZALD1 LTBP2 CHADL HTRA1 ECM1 SSPOP LTBP4 TNC	6.75e-11	656	31	12	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TRIL VWC2 LAMB4 LAMC3 KAZALD1 LTBP2 CHADL HTRA1 ECM1 SSPOP LTBP4 TNC	6.99e-11	658	31	12	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	VWC2 LAMB4 LAMC3 KAZALD1 LTBP2 CHADL HTRA1 ECM1 SSPOP LTBP4 TNC	1.34e-10	530	31	11	GO:0062023
GeneOntologyCellularComponent	interstitial matrix	VWC2 KAZALD1 TNC	1.98e-06	17	31	3	GO:0005614
GeneOntologyCellularComponent	basement membrane	VWC2 LAMB4 LAMC3 TNC	3.08e-05	122	31	4	GO:0005604
MousePheno	decreased interferon-beta secretion	TRIL TRIM65 TLR9	2.35e-05	33	24	3	MP:0008565
MousePheno	abnormal interferon-beta secretion	TRIL TRIM65 TLR9	9.30e-05	52	24	3	MP:0008558
Domain	Growth_fac_rcpt_	LAMC3 FAT1 KAZALD1 LTBP2 HTRA1 LTBP4 TNC	5.51e-09	156	31	7	IPR009030
Domain	EGF_1	LAMB4 LAMC3 FAT1 LTBP2 SSPOP LTBP4 TNC	1.62e-07	255	31	7	PS00022
Domain	EGF_2	LAMB4 LAMC3 FAT1 LTBP2 SSPOP LTBP4 TNC	2.10e-07	265	31	7	PS01186
Domain	-	LTBP2 FSTL3 LTBP4	2.31e-07	8	31	3	3.90.290.10
Domain	TB	LTBP2 FSTL3 LTBP4	3.45e-07	9	31	3	PS51364
Domain	TB_dom	LTBP2 FSTL3 LTBP4	3.45e-07	9	31	3	IPR017878
Domain	EGF-like_CS	LAMB4 LAMC3 FAT1 LTBP2 LTBP4 TNC	3.86e-06	261	31	6	IPR013032
Domain	LRR_8	LGR4 TRIL CHADL TLR9 LGR5	8.50e-06	171	31	5	PF13855
Domain	Leu-rich_rpt_typical-subtyp	LGR4 TRIL CHADL TLR9 LGR5	1.01e-05	177	31	5	IPR003591
Domain	LRR_TYP	LGR4 TRIL CHADL TLR9 LGR5	1.01e-05	177	31	5	SM00369
Domain	LRR	LGR4 TRIL CHADL TLR9 LGR5	1.86e-05	201	31	5	PS51450
Domain	LRRNT	LGR4 TRIL CHADL LGR5	2.01e-05	98	31	4	IPR000372
Domain	LRRNT	LGR4 TRIL CHADL LGR5	2.01e-05	98	31	4	SM00013
Domain	LRR_1	LGR4 TRIL CHADL TLR9 LGR5	2.81e-05	219	31	5	PF00560
Domain	VWFC_1	KCP VWC2 SSPOP	2.85e-05	36	31	3	PS01208
Domain	Kazal_2	KAZALD1 HTRA1 FSTL3	2.85e-05	36	31	3	PF07648
Domain	VWC	KCP VWC2 SSPOP	3.36e-05	38	31	3	SM00214
Domain	VWFC_2	KCP VWC2 SSPOP	3.36e-05	38	31	3	PS50184
Domain	EGF_3	FAT1 LTBP2 SSPOP LTBP4 TNC	3.93e-05	235	31	5	PS50026
Domain	EGF	LAMC3 FAT1 LTBP2 LTBP4 TNC	3.93e-05	235	31	5	SM00181
Domain	Gphrmn_rcpt_fam	LGR4 LGR5	3.98e-05	6	31	2	IPR002131
Domain	VWF_dom	KCP VWC2 SSPOP	4.55e-05	42	31	3	IPR001007
Domain	EGF-like_dom	LAMC3 FAT1 LTBP2 LTBP4 TNC	5.18e-05	249	31	5	IPR000742
Domain	TB	LTBP2 LTBP4	5.57e-05	7	31	2	PF00683
Domain	KAZAL	KAZALD1 HTRA1 FSTL3	5.99e-05	46	31	3	SM00280
Domain	KAZAL_2	KAZALD1 HTRA1 FSTL3	7.70e-05	50	31	3	PS51465
Domain	Leu-rich_rpt	LGR4 TRIL CHADL TLR9 LGR5	7.73e-05	271	31	5	IPR001611
Domain	Kazal_dom	KAZALD1 HTRA1 FSTL3	8.17e-05	51	31	3	IPR002350
Domain	-	LGR4 TRIL CHADL TLR9 LGR5	1.71e-04	321	31	5	3.80.10.10
Domain	L_dom-like	LGR4 TRIL CHADL TLR9 LGR5	1.89e-04	328	31	5	IPR032675
Domain	Unchr_dom_Cys-rich	KCP SSPOP	2.06e-04	13	31	2	IPR014853
Domain	C8	KCP SSPOP	2.06e-04	13	31	2	SM00832
Domain	-	CUL9 LAMC3 SSPOP	2.38e-04	73	31	3	2.60.120.260
Domain	TIL_dom	KCP SSPOP	2.40e-04	14	31	2	IPR002919
Domain	LAMININ_NTER	LAMB4 LAMC3	3.15e-04	16	31	2	PS51117
Domain	VWFD	KCP SSPOP	3.15e-04	16	31	2	PS51233
Domain	Laminin_N	LAMB4 LAMC3	3.15e-04	16	31	2	PF00055
Domain	VWD	KCP SSPOP	3.15e-04	16	31	2	SM00216
Domain	VWF_type-D	KCP SSPOP	3.15e-04	16	31	2	IPR001846
Domain	Laminin_N	LAMB4 LAMC3	3.15e-04	16	31	2	IPR008211
Domain	VWD	KCP SSPOP	3.15e-04	16	31	2	PF00094
Domain	LamNT	LAMB4 LAMC3	3.15e-04	16	31	2	SM00136
Domain	EGF_CA	FAT1 LTBP2 LTBP4	3.86e-04	86	31	3	PF07645
Domain	VWC_out	KCP SSPOP	4.48e-04	19	31	2	SM00215
Domain	IGFBP_N_2	KAZALD1 HTRA1	4.97e-04	20	31	2	PS51323
Domain	IGFBP-like	KAZALD1 HTRA1	4.97e-04	20	31	2	IPR000867
Domain	IGFBP	KAZALD1 HTRA1	4.97e-04	20	31	2	PF00219
Domain	Galactose-bd-like	CUL9 LAMC3 SSPOP	5.01e-04	94	31	3	IPR008979
Domain	EGF_Ca-bd_CS	FAT1 LTBP2 LTBP4	5.49e-04	97	31	3	IPR018097
Domain	EGF_CA	FAT1 LTBP2 LTBP4	5.83e-04	99	31	3	PS01187
Domain	ASX_HYDROXYL	FAT1 LTBP2 LTBP4	6.00e-04	100	31	3	PS00010
Domain	Kazal_1	KAZALD1 FSTL3	6.03e-04	22	31	2	PF00050
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT1 LTBP2 LTBP4	7.11e-04	106	31	3	IPR000152
Domain	VWC	KCP VWC2	9.81e-04	28	31	2	PF00093
Domain	EGF_CA	FAT1 LTBP2 LTBP4	1.07e-03	122	31	3	SM00179
Domain	EGF-like_Ca-bd_dom	FAT1 LTBP2 LTBP4	1.12e-03	124	31	3	IPR001881
Domain	EGF_LAM_2	LAMB4 LAMC3	1.13e-03	30	31	2	PS50027
Domain	EGF_LAM_1	LAMB4 LAMC3	1.13e-03	30	31	2	PS01248
Domain	EGF	FAT1 LTBP2 TNC	1.17e-03	126	31	3	PF00008
Domain	Laminin_EGF	LAMB4 LAMC3	1.53e-03	35	31	2	PF00053
Domain	EGF_Lam	LAMB4 LAMC3	1.53e-03	35	31	2	SM00180
Domain	Laminin_EGF	LAMB4 LAMC3	1.81e-03	38	31	2	IPR002049
Domain	LRRNT	LGR4 LGR5	3.49e-03	53	31	2	PF01462
Domain	EGF_extracell	LTBP2 TNC	4.44e-03	60	31	2	IPR013111
Domain	EGF_2	LTBP2 TNC	4.44e-03	60	31	2	PF07974
Domain	Cys-rich_flank_reg_C	TRIL CHADL	9.75e-03	90	31	2	IPR000483
Domain	LRRCT	TRIL CHADL	9.75e-03	90	31	2	SM00082
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LAMC3 LTBP2 HTRA1 LTBP4 TNC	1.04e-04	300	23	5	M610
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMB4 LAMC3 TNC	3.32e-04	84	23	3	M7098
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO	LGR4 LGR5	4.28e-04	19	23	2	M47833
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR4 LGR5	5.25e-04	21	23	2	M27401
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LTBP2 HTRA1 LTBP4 TNC	7.38e-04	258	23	4	MM14572
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	LTBP2 FSTL3 LTBP4	8.96e-04	118	23	3	MM15588
Pathway	WP_WHITE_FAT_CELL_DIFFERENTIATION	EGR2 ZNF423	1.23e-03	32	23	2	M39333
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	LTBP2 LTBP4	1.23e-03	32	23	2	MM14854
Pathway	WP_WHITE_FAT_CELL_DIFFERENTIATION	EGR2 ZNF423	1.30e-03	33	23	2	MM15869
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	LTBP2 LTBP4	1.64e-03	37	23	2	M27134
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	LTBP2 LTBP4	1.73e-03	38	23	2	MM14874
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LTBP2 LTBP4	1.82e-03	39	23	2	MM14601
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	LTBP2 FSTL3 LTBP4	2.19e-03	161	23	3	M27871
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LTBP2 LTBP4	2.31e-03	44	23	2	M26969
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	LTBP2 LTBP4	2.63e-03	47	23	2	M646
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	LTBP2 HTRA1 FSTL3 ECM1 LTBP4 TNC	9.60e-08	248	32	6	24006456
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LTBP2 HTRA1 ECM1 LTBP4 TNC	2.24e-07	146	32	5	27068509
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	LTBP2 HTRA1 ECM1 LTBP4 TNC	4.36e-07	167	32	5	22159717
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LTBP2 ECM1 SSPOP LTBP4 TNC	5.49e-07	175	32	5	28071719
Pubmed	Latent TGF-β binding protein 2 and 4 have essential overlapping functions in microfibril development.	LTBP2 LTBP4	8.20e-07	2	32	2	28252045
Pubmed	Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.	LGR4 LGR5	8.20e-07	2	32	2	36410420
Pubmed	Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.	LGR4 LGR5	8.20e-07	2	32	2	9849958
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	LTBP2 HTRA1 LTBP4 TNC	2.26e-06	101	32	4	20551380
Pubmed	Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.	LGR4 LGR5	2.46e-06	3	32	2	28634819
Pubmed	Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases.	LGR4 LGR5	2.46e-06	3	32	2	33262293
Pubmed	Clinical Significance of Stem Cell Biomarkers EpCAM, LGR5 and LGR4 mRNA Levels in Lymph Nodes of Colon Cancer Patients.	LGR4 LGR5	2.46e-06	3	32	2	35008827
Pubmed	R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.	LGR4 LGR5	2.46e-06	3	32	2	21693646
Pubmed	Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts.	LGR4 LGR5	2.46e-06	3	32	2	28777797
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP2 LTBP4	4.92e-06	4	32	2	15611103
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP2 LTBP4	4.92e-06	4	32	2	11104663
Pubmed	R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.	LGR4 LGR5	8.19e-06	5	32	2	22815884
Pubmed	Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.	LGR4 LGR5	8.19e-06	5	32	2	23393138
Pubmed	LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.	LGR4 LGR5	8.19e-06	5	32	2	37402772
Pubmed	NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.	LGR4 LGR5	8.19e-06	5	32	2	31867777
Pubmed	Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.	FAT1 LGR5	8.19e-06	5	32	2	33328637
Pubmed	Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.	LGR4 LGR5	1.23e-05	6	32	2	24225776
Pubmed	Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.	LGR4 LGR5	1.23e-05	6	32	2	21727895
Pubmed	Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.	LGR4 LGR5	1.72e-05	7	32	2	37651925
Pubmed	Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.	LTBP2 LTBP4	1.72e-05	7	32	2	10930463
Pubmed	Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.	LGR4 LGR5	1.72e-05	7	32	2	32457899
Pubmed	Phosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphatase.	RACGAP1 PTPA	1.72e-05	7	32	2	18201571
Pubmed	Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.	LGR4 LGR5	1.72e-05	7	32	2	29752411
Pubmed	Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium.	LGR4 LGR5	2.29e-05	8	32	2	24139799
Pubmed	R-spondins/Lgrs expression in tooth development.	LGR4 LGR5	2.29e-05	8	32	2	24616052
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	CHADL SSPOP TNC	2.84e-05	64	32	3	22261194
Pubmed	Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.	LGR4 LGR5	2.94e-05	9	32	2	21508962
Pubmed	A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns.	TLR9 LGR5	2.94e-05	9	32	2	30170812
Pubmed	Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.	LGR4 LGR5	4.49e-05	11	32	2	20223988
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	VWC2 LAMC3 KAZALD1	5.34e-05	79	32	3	18757743
Pubmed	The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.	LGR4 LGR5	5.38e-05	12	32	2	30146491
Pubmed	RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.	LGR4 LGR5	5.38e-05	12	32	2	29769720
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	LTBP2 HTRA1 TNC	6.87e-05	86	32	3	28327460
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LGR4 LAMC3 FAT1 LTBP2 HTRA1 FSTL3 ECM1	9.08e-05	1201	32	7	35696571
Pubmed	Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii.	LGR5 TNC	9.76e-05	16	32	2	36165446
Pubmed	Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.	LGR4 LGR5	9.76e-05	16	32	2	29859889
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	LTBP2 LTBP4 TNC	9.84e-05	97	32	3	27559042
Pubmed	LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.	LGR4 LGR5	1.11e-04	17	32	2	27559308
Pubmed	Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.	ECM1 TNC	1.11e-04	17	32	2	27398409
Pubmed	Marker genes identify three somatic cell types in the fetal mouse ovary.	LGR4 LGR5	1.11e-04	17	32	2	25158167
Pubmed	Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice.	LGR4 LGR5	1.24e-04	18	32	2	26776520
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMB4 LAMC3	1.24e-04	18	32	2	11311202
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	LGR4 LGR5	1.70e-04	21	32	2	27088858
Pubmed	Schwann cell myelination requires integration of laminin activities.	LAMC3 EGR2	1.70e-04	21	32	2	22767514
Pubmed	Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.	LGR4 LGR5	2.05e-04	23	32	2	24680895
Pubmed	LGR5 controls extracellular matrix production by stem cells in the developing intestine.	LGR4 LGR5	2.05e-04	23	32	2	32468660
Pubmed	Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.	LGR4 LGR5	2.24e-04	24	32	2	31772170
Pubmed	Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.	FAT1 TNC	2.24e-04	24	32	2	26116661
Pubmed	Tissue-specific activities of the Fat1 cadherin cooperate to control neuromuscular morphogenesis.	FAT1 TNC	2.43e-04	25	32	2	29768404
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMC3 ECM1	2.63e-04	26	32	2	24742657
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	TRIM65 KAZALD1 PTPA FSTL3 MIR1915HG SAMD11	2.97e-04	1021	32	6	26760575
Pubmed	Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.	CHRNA10 TNC	3.05e-04	28	32	2	22808246
Pubmed	CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.	LGR4 ADRB3 ZNF423	3.29e-04	146	32	3	29688375
Pubmed	Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function.	HTRA1 TNC	3.51e-04	30	32	2	32634398
Pubmed	TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis.	TLR9 LGR5	3.51e-04	30	32	2	25063677
Pubmed	R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.	LGR4 LGR5	3.51e-04	30	32	2	32324134
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	ECM1 LTBP4 TNC	3.77e-04	153	32	3	25037231
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CUL9 LAMC3 FAT1 KAZALD1 LTBP4 REPIN1	4.53e-04	1105	32	6	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	LGR4 CUL9 FAT1 HTRA1 LTBP4 REPIN1	4.77e-04	1116	32	6	31753913
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	LTBP2 LTBP4	5.07e-04	36	32	2	20587546
Pubmed	Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.	EGR2 LTBP4	5.07e-04	36	32	2	23213481
Pubmed	Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin.	LAMC3 TNC	5.65e-04	38	32	2	27653694
Pubmed	Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.	LGR4 LGR5	8.64e-04	47	32	2	28813421
Pubmed	Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.	ADRB3 ZNF423	8.64e-04	47	32	2	32892421
Cytoband	7q36.1	SSPOP REPIN1	1.23e-03	74	32	2	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	SSPOP REPIN1	5.52e-03	159	32	2	chr7q36
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP2 LTBP4	8.47e-06	4	22	2	628
GeneFamily	Laminin subunits	LAMB4 LAMC3	9.26e-05	12	22	2	626
GeneFamily	G protein-coupled receptors, Class A orphans	LGR4 LGR5	4.01e-03	78	22	2	262
Coexpression	NABA_CORE_MATRISOME	KCP LAMB4 LAMC3 LTBP2 CHADL ECM1 SSPOP LTBP4 TNC	3.07e-11	275	32	9	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	KCP LAMB4 LAMC3 LTBP2 ECM1 SSPOP LTBP4 TNC	7.64e-11	196	32	8	M3008
Coexpression	NABA_MATRISOME	KCP VWC2 LAMB4 LAMC3 KAZALD1 LTBP2 CHADL HTRA1 FSTL3 ECM1 SSPOP LTBP4 TNC	8.17e-11	1026	32	13	M5889
Coexpression	NABA_CORE_MATRISOME	KCP LAMC3 LTBP2 CHADL ECM1 SSPOP LTBP4 TNC	9.71e-10	270	32	8	MM17057
Coexpression	NABA_MATRISOME	KCP VWC2 LAMC3 KAZALD1 LTBP2 CHADL HTRA1 FSTL3 ECM1 SSPOP LTBP4 TNC	1.09e-09	1008	32	12	MM17056
Coexpression	NABA_ECM_GLYCOPROTEINS	KCP LAMC3 LTBP2 ECM1 SSPOP LTBP4 TNC	2.82e-09	191	32	7	MM17059
Coexpression	NABA_MATRISOME_POORLY_METASTATIC_MELANOMA	LTBP2 HTRA1 ECM1	1.35e-05	38	32	3	M47982
Coexpression	MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP	HTRA1 ECM1 EGR2 TNC	5.09e-05	168	32	4	M1124
Coexpression	MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP	HTRA1 ECM1 EGR2 TNC	6.95e-05	182	32	4	MM993
Coexpression	CUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL	KAZALD1 LTBP2 HTRA1 LTBP4	8.72e-05	193	32	4	M39321
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	HTRA1 FSTL3 ECM1 TNC	1.00e-04	200	32	4	M5930
Coexpression	XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP	LTBP2 ECM1	1.12e-04	13	32	2	M17359
Coexpression	HEBERT_MATRISOME_TNBC_LIVER_METASTASIS	ECM1 TNC	1.30e-04	14	32	2	M48002
Coexpression	MCLACHLAN_DENTAL_CARIES_DN	LGR4 LGR5 ZNF423	1.37e-04	82	32	3	M1278
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	RACGAP1 TRIL FAT1 EGR2 TNC	1.79e-04	439	32	5	M39054
Coexpression	FEKIR_HEPARG_SIDE_POP_VS_HEPARG_UP	FAT1 FSTL3 TNC	1.81e-04	90	32	3	M48360
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	KAZALD1 LTBP2 HTRA1 LGR5 EGR2 TNC	2.09e-04	721	32	6	M1999
Coexpression	BOQUEST_STEM_CELL_UP	FAT1 LTBP2 HTRA1 TNC	2.77e-04	261	32	4	M1834
Coexpression	HAY_BONE_MARROW_STROMAL	FAT1 LTBP2 HTRA1 TNC SAMD11 ZNF423	2.91e-04	767	32	6	M39209
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	LGR4 TRIL FAT1 KAZALD1 HTRA1 LGR5 EGR2 LTBP4 TNC	1.34e-06	768	32	9	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	LGR4 RACGAP1 FAT1 KAZALD1 LGR5 EGR2 LTBP4 TNC ZNF423	1.75e-06	793	32	9	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000	KCP LGR4 TRIM65 LTBP2 HTRA1 LGR5 MIR1915HG LTBP4 TNC	9.27e-06	973	32	9	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	LGR4 TRIL FAT1 KAZALD1 HTRA1 EGR2 LTBP4 ZNF423	1.44e-05	773	32	8	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	FAT1 LTBP2 HTRA1 ECM1 LTBP4 TNC	5.29e-05	455	32	6	GSM777055_500
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000	KCP CTBS LTBP2 ECM1 LGR5 SSPOP TNC SAMD11	7.93e-05	982	32	8	PCBC_ratio_MESO-5_vs_SC_1000
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#4	CTBS LTBP2 ECM1 TNC	8.59e-05	156	32	4	ratio_MESO_vs_SC_1000_K4
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	LGR4 TRIL HTRA1 EGR2 LTBP4 TNC ZNF423	1.29e-04	777	32	7	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200	FAT1 KAZALD1 LGR5 EGR2	1.40e-04	177	32	4	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_200
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	KCP KAZALD1 LTBP2 ADRB3 ECM1 LGR5 SSPOP SAMD11	1.68e-04	1094	32	8	ratio_EB_vs_SC_2500_K3
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	LGR4 FAT1 KAZALD1 EGR2 LTBP4	1.98e-04	364	32	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1	KAZALD1 LTBP2 HTRA1 LGR5 TNC	2.51e-04	383	32	5	Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3	KAZALD1 LTBP2 HTRA1 LGR5 TNC	3.43e-04	410	32	5	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#3_top-relative-expression-ranked_500	LAMC3 KAZALD1 LTBP4	3.80e-04	94	32	3	gudmap_developingGonad_e18.5_testes_500_k3
CoexpressionAtlas	geo_heart_top-relative-expression-ranked_2500_k-means-cluster#1	RACGAP1 FSTL3 ECM1 REPIN1	3.99e-04	233	32	4	geo_heart_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#1	KAZALD1 LTBP2 HTRA1 LGR5 TNC	4.41e-04	433	32	5	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K1
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500	FAT1 KAZALD1 HTRA1 LGR5 EGR2	4.41e-04	433	32	5	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500
CoexpressionAtlas	ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_100	LGR5 TNC SAMD11	4.42e-04	99	32	3	PCBC_ratio_DE_vs_SC_100
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500	FAT1 KAZALD1 HTRA1 LGR5 EGR2	4.79e-04	441	32	5	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	FAT1 HTRA1 ECM1 LTBP4 TNC	4.99e-04	445	32	5	GSM777043_500
CoexpressionAtlas	Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2	FAT1 HTRA1 ECM1 LTBP4 TNC	5.41e-04	453	32	5	GSM777067_500
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_1000	FAT1 KAZALD1 LTBP2 FSTL3 ECM1 EGR2 SAMD11	5.66e-04	990	32	7	JC_fibro_1000
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1	KAZALD1 LTBP2 ECM1 EGR2 SAMD11	6.03e-04	464	32	5	JC_fibro_1000_K1
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	FAT1 HTRA1 ECM1 LTBP4 TNC	6.15e-04	466	32	5	GSM777050_500
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_500	LAMC3 KAZALD1 LTBP4	7.20e-04	117	32	3	gudmap_developingGonad_P2_testes_500_k2
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	LGR4 TRIL HTRA1 LGR5 EGR2 LTBP4	7.33e-04	740	32	6	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#1	KAZALD1 LTBP2 HTRA1 LGR5 TNC	9.07e-04	508	32	5	Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#2_top-relative-expression-ranked_100	KAZALD1 HTRA1	9.32e-04	30	32	2	gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_100_k2
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1	LGR5 SAMD11	9.96e-04	31	32	2	ratio_ECTO_vs_SC_1000_K1
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LTBP2 FSTL3 ECM1 LTBP4 SAMD11 ZNF423	5.89e-09	200	32	6	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LAMC3 LTBP2 FSTL3 ECM1 LTBP4 TNC	5.89e-09	200	32	6	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LTBP2 FSTL3 ECM1 LTBP4 TNC SAMD11	5.89e-09	200	32	6	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LGR4 TRIL LAMC3 CHRNA10 SLX1A	1.13e-07	164	32	5	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL LAMC3 KAZALD1 LTBP4 TNC	1.13e-07	164	32	5	01a7c335897128d3478b8b9b44fb461cab493084
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMC3 LTBP2 FSTL3 REPIN1 TNC	1.23e-07	167	32	5	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL LAMC3 LGR5 LTBP4 TNC	1.89e-07	182	32	5	af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL LAMC3 LGR5 LTBP4 TNC	1.89e-07	182	32	5	b7d532feb73167e05475855061b35a209583f44c
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	LTBP2 HTRA1 ECM1 LTBP4 TNC	2.40e-07	191	32	5	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 HTRA1 ECM1 LTBP4 SAMD11	2.46e-07	192	32	5	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.53e-07	193	32	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LGR4 LAMC3 FAT1 LTBP2 HTRA1	2.53e-07	193	32	5	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.53e-07	193	32	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 ECM1 LGR5 LTBP4 TNC	2.59e-07	194	32	5	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.59e-07	194	32	5	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.59e-07	194	32	5	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LGR4 LAMC3 FAT1 LTBP2 HTRA1	2.59e-07	194	32	5	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	18-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	KAZALD1 LTBP2 FSTL3 LTBP4 TNC	2.66e-07	195	32	5	f86737bff21d81673238813df61a15cfe88d0b15
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 HTRA1 ECM1 LTBP4 SAMD11	2.66e-07	195	32	5	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAZALD1 HTRA1 ECM1 LTBP4 TNC	2.73e-07	196	32	5	f47e551ba484687ba6ce8c29a085106131364042
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 ECM1 LGR5 LTBP4 SAMD11	2.73e-07	196	32	5	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 ECM1 LGR5 LTBP4 SAMD11	2.73e-07	196	32	5	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 ECM1 LGR5 LTBP4 SAMD11	2.73e-07	196	32	5	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KAZALD1 LTBP2 HTRA1 LTBP4 TNC	2.80e-07	197	32	5	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.80e-07	197	32	5	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWC2 ECM1 LTBP4 TNC SAMD11	2.87e-07	198	32	5	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIL LTBP2 HTRA1 LTBP4 TNC	2.87e-07	198	32	5	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	LAMC3 LTBP2 ECM1 LTBP4 TNC	2.87e-07	198	32	5	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	distal-1-mesenchymal-Myofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LTBP2 FSTL3 ECM1 LTBP4 TNC	2.94e-07	199	32	5	58c36f5a30c6862b7f5587a0b9bc31da99e43dd5
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	LTBP2 HTRA1 FSTL3 ECM1 TNC	3.02e-07	200	32	5	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LTBP2 FSTL3 ECM1 LTBP4 SAMD11	3.02e-07	200	32	5	6316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP2 HTRA1 FSTL3 ECM1 LTBP4	3.02e-07	200	32	5	db6281b5d4032116310db379d9175d790994c99c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FSTL3 ECM1 LTBP4 TNC SAMD11	3.02e-07	200	32	5	7642a14855589b0b3f68dbdc9e4d3fc7291854f7
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP2 HTRA1 FSTL3 ECM1 LTBP4	3.02e-07	200	32	5	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	Fibroblast\|World / shred by cell class for parenchyma	LTBP2 FSTL3 ECM1 LTBP4 SAMD11	3.02e-07	200	32	5	dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	LTBP2 HTRA1 FSTL3 ECM1 TNC	3.02e-07	200	32	5	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP2 ECM1 LTBP4 TNC SAMD11	3.02e-07	200	32	5	c5d818203bef80ff97c2e0158cf61970673dd258
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FSTL3 ECM1 LTBP4 TNC SAMD11	3.02e-07	200	32	5	444c72334df421375ae6fc69b0adfd4950d49a43
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FSTL3 ECM1 LTBP4 TNC SAMD11	3.02e-07	200	32	5	5826c17da67bdaba3a828792279004218d8260c8
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP2 HTRA1 FSTL3 ECM1 LTBP4	3.02e-07	200	32	5	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	LTBP2 ECM1 LTBP4 TNC SAMD11	3.02e-07	200	32	5	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRIL LTBP2 HTRA1 FSTL3 LTBP4	3.02e-07	200	32	5	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LAMC3 LTBP2 HTRA1 TNC	4.52e-06	155	32	4	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIL LAMC3 ADRB3 EGR2	4.76e-06	157	32	4	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VWC2 KAZALD1 CHADL LGR5	5.25e-06	161	32	4	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGR4 VWC2 CHADL ZNF423	5.93e-06	166	32	4	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGR4 VWC2 CHADL ZNF423	5.93e-06	166	32	4	81c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell	Basal_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	LGR4 LGR5 LTBP4 TNC	5.93e-06	166	32	4	23c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_naive\|bone_marrow / Manually curated celltypes from each tissue	LGR4 KAZALD1 TLR9 REPIN1	6.67e-06	171	32	4	fcc31a9a69f96de10d1324a5a4fbfe4289bf4984
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	ADRB3 FSTL3 MIR1915HG ZNF423	6.82e-06	172	32	4	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KAZALD1 HTRA1 ADRB3 LTBP4	7.47e-06	176	32	4	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	TRIL LTBP2 LGR5 SAMD11	7.64e-06	177	32	4	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TRIL LTBP2 LGR5 SAMD11	7.64e-06	177	32	4	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMC3 KAZALD1 LGR5 LTBP4	7.99e-06	179	32	4	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL KAZALD1 LTBP4 TNC	8.16e-06	180	32	4	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWC2 LAMC3 HTRA1 EGR2	8.16e-06	180	32	4	e9785ac2806103f725f5a5208495826354ec6e22
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 CHRNA10 ECM1 LGR5	8.34e-06	181	32	4	a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCell	normal_Lung-Fibroblasts-Pericytes\|normal_Lung / Location, Cell class and cell subclass	LAMC3 FAT1 LTBP2 ECM1	8.34e-06	181	32	4	f74941e49950027360d71ea3b205fc20c6929766
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 CHRNA10 ECM1 LGR5	8.34e-06	181	32	4	504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 CHRNA10 ECM1 LGR5	8.34e-06	181	32	4	a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAZALD1 HTRA1 LTBP4 ZNF423	8.53e-06	182	32	4	aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LGR4 LAMC3 LTBP2 TNC	8.53e-06	182	32	4	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTRA1 FSTL3 LTBP4 SAMD11	8.71e-06	183	32	4	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIL LAMC3 ADRB3 ECM1	8.71e-06	183	32	4	8de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMB4 FAT1 ECM1 TNC	8.71e-06	183	32	4	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT1 LTBP4 TNC SAMD11	9.09e-06	185	32	4	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LGR4 VWC2 FAT1 HTRA1	9.29e-06	186	32	4	948815663c212c4311329d503b5991cbbbff9808
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC3 ECM1 LTBP4 TNC	9.29e-06	186	32	4	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMC3 KAZALD1 ADRB3 ECM1	9.49e-06	187	32	4	ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LGR4 LTBP2 HTRA1 SAMD11	9.49e-06	187	32	4	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 ECM1 LTBP4 ZNF423	9.49e-06	187	32	4	2c145e9d11424939dd99012a8cedf5d998b966e9
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LGR4 LTBP2 HTRA1 FSTL3	9.69e-06	188	32	4	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RACGAP1 LTBP2 HTRA1 TNC	9.69e-06	188	32	4	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LGR4 LTBP2 HTRA1 SAMD11	9.69e-06	188	32	4	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP2 HTRA1 ADRB3 FSTL3	9.89e-06	189	32	4	f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCell	facs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWC2 KAZALD1 ECM1 LTBP4	9.89e-06	189	32	4	7c6d586f352d0d44c24079e76272cb3a545441b5
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 FSTL3 ECM1 EGR2	9.89e-06	189	32	4	562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL LAMC3 KAZALD1 TNC	9.89e-06	189	32	4	9e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Airway_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KAZALD1 LTBP2 LTBP4 TNC	9.89e-06	189	32	4	4f9608b84d135268a17455661870c46ae8554a24
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	LGR4 TRIL LTBP4 TNC	9.89e-06	189	32	4	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	facs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWC2 KAZALD1 ECM1 LTBP4	9.89e-06	189	32	4	5438baaa3056fec46d59f75f03f27a93601936c1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 FSTL3 ECM1 EGR2	9.89e-06	189	32	4	270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAZALD1 HTRA1 LGR5 TNC	1.01e-05	190	32	4	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAZALD1 HTRA1 LGR5 TNC	1.01e-05	190	32	4	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAZALD1 LTBP2 ECM1 LTBP4	1.01e-05	190	32	4	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIL LAMC3 KAZALD1 TNC	1.01e-05	190	32	4	7f6dafd5418764d67f6d5ec2153233b791910e81
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	LGR4 FAT1 LTBP4 TNC	1.03e-05	191	32	4	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 HTRA1 ECM1 LTBP4	1.03e-05	191	32	4	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	LTBP2 LTBP4 TNC SAMD11	1.03e-05	191	32	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	LTBP2 LTBP4 TNC SAMD11	1.03e-05	191	32	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP2 CHADL LGR5 LTBP4	1.03e-05	191	32	4	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	facs-Trachea-nan-18m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIL HTRA1 ECM1 LTBP4	1.03e-05	191	32	4	783e8c436de90623bb1bc4117270d60c8c8a9461
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LTBP2 HTRA1 ECM1 TNC	1.05e-05	192	32	4	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWC2 FAT1 LTBP2 LGR5	1.05e-05	192	32	4	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	P28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LTBP2 HTRA1 FSTL3 ECM1	1.05e-05	192	32	4	87c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LTBP2 HTRA1 ECM1 TNC	1.05e-05	192	32	4	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LGR4 TRIL FAT1 LTBP2	1.05e-05	192	32	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 ADRB3 ECM1 LTBP4	1.05e-05	192	32	4	5876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LTBP2 HTRA1 ECM1 SAMD11	1.07e-05	193	32	4	b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	LAMC3 LTBP2 HTRA1 SAMD11	1.07e-05	193	32	4	cf2461af78f65616ce40d552ee9452295e3895ed
Drug	Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A	LAMB4 CHRNA10 LTBP4 TNC ZNF423	7.12e-06	194	32	5	4371_UP
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A	LAMB4 KAZALD1 CHRNA10 LGR5 LTBP4	7.68e-06	197	32	5	6759_UP
Disease	osteoarthritis, hip	LTBP2 CHADL TNC	1.12e-04	92	30	3	EFO_1000786
Disease	response to mitochondrial complex I inhibitor	VWC2 LTBP4	1.69e-04	19	30	2	EFO_0600033
Disease	Osteoarthritis of hip	CHADL TNC	1.88e-04	20	30	2	C0029410
Disease	Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine	LTBP2 ZNF423	6.51e-04	37	30	2	EFO_0004276, EFO_0004775, EFO_0006997
Disease	esophagus squamous cell carcinoma (is_implicated_in)	FAT1 HTRA1	9.63e-04	45	30	2	DOID:3748 (is_implicated_in)
Disease	esophagus squamous cell carcinoma (is_marker_for)	FAT1 HTRA1	2.58e-03	74	30	2	DOID:3748 (is_marker_for)
Disease	Glioblastoma	FAT1 LTBP4	2.93e-03	79	30	2	C0017636
Disease	age of onset of asthma	PTPA LTBP2	2.93e-03	79	30	2	OBA_2001001

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPCHEPRCLCRQEAL	CHRNA10	381	Q9GZZ6
CRCGRRLPPEPCAAA	ADRB3	361	P13945
AAGTDCPCPEPELCR	CTBS	36	Q01459
CPCPEPELCRPIRHH	CTBS	41	Q01459
HERPYPCPAEGCDRR	EGR2	336	P11161
RCPPVHHGCEDDPCP	FAT1	3786	Q14517
PDRPERPECADACCY	MIR1915HG	96	Q5T4H9
EGCAPCRPEECAAPR	KAZALD1	51	Q96I82
QERCCVPPGERCPSA	HHLA2	386	Q9UM44
PPLCAAPCSCDGDRR	LGR4	26	Q9BXB1
CEPARCPPQPEHCEG	HTRA1	41	Q92743
RPRCECAPDCSGLPA	FSTL3	116	O95633
INECRHPGTCPDGRC	LTBP2	971	Q14767
ECLDVDECHRVPPPC	LTBP4	626	Q8N2S1
DECHRVPPPCDLGRC	LTBP4	631	Q8N2S1
HPCPCNRFAELCDPE	LAMB4	861	A4D0S4
RPDHCPVCVSPLGCD	CUL9	2066	Q8IWT3
RADVECPPAHTCPCG	CRIPAK	161	Q8N1N5
AECPPAHTCRCGVPA	CRIPAK	226	Q8N1N5
HLCCRHPPSPTRDEC	ECM1	381	Q16610
RAVAPCPRACVCVPE	CHADL	391	Q6NUI6
LRGCPTHCHCEPDGR	LGR5	31	O75473
DERCVPPDLCPCRHS	SSPOP	966	A2VEC9
EPGSCCPSCRREAPE	SSPOP	5036	A2VEC9
PGDPCRICRCLEGHI	KCP	271	Q6ZWJ8
DFPHPSDPCRLCRCL	KCP	616	Q6ZWJ8
LQVHPPICDCPGCRI	SAMD11	6	Q96NU1
VVSHPECRDRCPLPC	RACGAP1	321	Q9H0H5
RDHAPDRPFVCPDCG	REPIN1	451	Q9BWE0
LCAQPECPRLHPRCI	VWC2	186	Q2TAL6
RRCDHAPNPCMECPR	TLR9	256	Q9NR96
CDECIPLPRAGHCAP	PTPA	91	Q15257
PLAEPVCPERCDCQH	TRIL	21	Q7L0X0
SEPECPGNCHLRGRC	TNC	186	P24821
EEGPLCCPHPGCLLR	SLX1A	196	Q9BQ83
EPADRPCAGLRCPEC	ZNF423	1111	Q2M1K9
DRCGKACPECREPFP	TRIM65	41	Q6PJ69
HCPPGQRGRRCEVCD	LAMC3	776	Q9Y6N6