Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	eukaryotic initiation factor 4E binding	EIF4G1 EIF4EBP3	4.33e-04	11	57	2	GO:0008190
GeneOntologyMolecularFunction	transcription coactivator binding	ZBTB49 NFATC1 RUNX1	4.93e-04	54	57	3	GO:0001223
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	TSC22D1 NFATC1 VASN PDPK1 LRP1 RUNX1 LTBP4 LDLRAD4	3.76e-06	336	57	8	GO:0071560
GeneOntologyBiologicalProcess	response to transforming growth factor beta	TSC22D1 NFATC1 VASN PDPK1 LRP1 RUNX1 LTBP4 LDLRAD4	4.38e-06	343	57	8	GO:0071559
GeneOntologyBiologicalProcess	somatic sensory system development	ULK1 ULK2	7.50e-06	2	57	2	GO:0160038
GeneOntologyBiologicalProcess	regulation of transforming growth factor beta receptor signaling pathway	TSC22D1 VASN PDPK1 LRP1 LTBP4 LDLRAD4	1.47e-05	192	57	6	GO:0017015
GeneOntologyBiologicalProcess	regulation of cellular response to transforming growth factor beta stimulus	TSC22D1 VASN PDPK1 LRP1 LTBP4 LDLRAD4	1.61e-05	195	57	6	GO:1903844
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	TSC22D1 VASN PDPK1 LRP1 ULK1 RUNX2 LTBP4 LDLRAD4	1.66e-05	412	57	8	GO:0090287
GeneOntologyBiologicalProcess	regulation of cell size	PLXNA4 LRP1 TSC1 ULK1 CCDC51 ULK2	3.60e-05	225	57	6	GO:0008361
GeneOntologyBiologicalProcess	regulation of collateral sprouting	LRP1 ULK1 ULK2	4.41e-05	25	57	3	GO:0048670
GeneOntologyBiologicalProcess	stem cell proliferation	TSC22D1 NFATC1 GLI2 RUNX2 RUNX1	7.08e-05	156	57	5	GO:0072089
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	TSC22D1 NFATC1 VASN PDPK1 LRP1 ULK1 RUNX2 RUNX1 LTBP4 LDLRAD4	9.96e-05	850	57	10	GO:0071363
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	TSC22D1 VASN PDPK1 LRP1 LTBP4 LDLRAD4	1.11e-04	276	57	6	GO:0007179
GeneOntologyBiologicalProcess	axon guidance	GLI2 CNTN5 PLXNA4 LRP1 ULK1 ULK2	1.33e-04	285	57	6	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	GLI2 CNTN5 PLXNA4 LRP1 ULK1 ULK2	1.35e-04	286	57	6	GO:0097485
GeneOntologyBiologicalProcess	response to growth factor	TSC22D1 NFATC1 VASN PDPK1 LRP1 ULK1 RUNX2 RUNX1 LTBP4 LDLRAD4	1.36e-04	883	57	10	GO:0070848
GeneOntologyBiologicalProcess	collateral sprouting	LRP1 ULK1 ULK2	1.45e-04	37	57	3	GO:0048668
GeneOntologyBiologicalProcess	regulation of cellular component size	PLXNA4 LRP1 TSC1 CDHR5 ULK1 CCDC51 ULK2	1.66e-04	426	57	7	GO:0032535
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	TSC22D1 VASN PDPK1 LRP1 RUNX2 LTBP4 LDLRAD4	2.16e-04	445	57	7	GO:0141091
GeneOntologyBiologicalProcess	regulation of growth	NACA EIF4G1 PLXNA4 LRP1 ULK1 RUNX1 LTBP4 ULK2 PYHIN1	2.59e-04	777	57	9	GO:0040008
GeneOntologyBiologicalProcess	cerebellar cortex morphogenesis	WHRN GLI2 ULK1	3.17e-04	48	57	3	GO:0021696
GeneOntologyBiologicalProcess	regulation of stem cell proliferation	TSC22D1 NFATC1 GLI2 RUNX2	3.29e-04	119	57	4	GO:0072091
GeneOntologyBiologicalProcess	cell surface receptor protein serine/threonine kinase signaling pathway	TSC22D1 VASN PDPK1 LRP1 RUNX2 LTBP4 LDLRAD4	3.51e-04	482	57	7	GO:0007178
GeneOntologyBiologicalProcess	regulation of extent of cell growth	PLXNA4 LRP1 ULK1 ULK2	3.61e-04	122	57	4	GO:0061387
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	TSC22D1 VASN PDPK1 LRP1 LTBP4 LDLRAD4	3.83e-04	347	57	6	GO:0090092
GeneOntologyBiologicalProcess	negative regulation of collateral sprouting	ULK1 ULK2	4.86e-04	12	57	2	GO:0048671
GeneOntologyBiologicalProcess	axon extension	PLXNA4 LRP1 ULK1 ULK2	5.30e-04	135	57	4	GO:0048675
GeneOntologyBiologicalProcess	regulation of cell growth	EIF4G1 PLXNA4 LRP1 ULK1 LTBP4 ULK2 PYHIN1	5.46e-04	519	57	7	GO:0001558
GeneOntologyBiologicalProcess	negative regulation of transforming growth factor beta receptor signaling pathway	VASN PDPK1 LRP1 LDLRAD4	5.76e-04	138	57	4	GO:0030512
GeneOntologyBiologicalProcess	cerebellum morphogenesis	WHRN GLI2 ULK1	6.12e-04	60	57	3	GO:0021587
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	TSC22D1 TRIM11 NFATC1 VASN GLI2 ULK1 RUNX1 ULK2 LDLRAD4	6.16e-04	875	57	9	GO:0045596
GeneOntologyBiologicalProcess	hindbrain morphogenesis	WHRN GLI2 ULK1	7.40e-04	64	57	3	GO:0021575
GeneOntologyBiologicalProcess	molting cycle	NFATC1 GLI2 EPS8L3 RUNX1	7.87e-04	150	57	4	GO:0042303
GeneOntologyBiologicalProcess	hair cycle	NFATC1 GLI2 EPS8L3 RUNX1	7.87e-04	150	57	4	GO:0042633
Domain	ZnF_C2HC	FAM90A14 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	9.03e-09	55	52	6	SM00343
Domain	Znf_CCHC	FAM90A14 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	9.03e-09	55	52	6	IPR001878
Domain	Ser/Thr_kinase_C	ULK1 ULK2	7.60e-06	2	52	2	IPR022708
Domain	DUF3543	ULK1 ULK2	7.60e-06	2	52	2	PF12063
Domain	Ser/Thr_kin_STPK_Ulk-1/2	ULK1 ULK2	7.60e-06	2	52	2	IPR016237
Domain	Runt	RUNX2 RUNX1	2.28e-05	3	52	2	PF00853
Domain	Runt_dom	RUNX2 RUNX1	2.28e-05	3	52	2	IPR013524
Domain	RunxI_C_dom	RUNX2 RUNX1	2.28e-05	3	52	2	IPR013711
Domain	RUNT	RUNX2 RUNX1	2.28e-05	3	52	2	PS51062
Domain	Runx_central_dom	RUNX2 RUNX1	2.28e-05	3	52	2	IPR027384
Domain	-	RUNX2 RUNX1	2.28e-05	3	52	2	4.10.770.10
Domain	TF_Runt-rel_RUNX	RUNX2 RUNX1	2.28e-05	3	52	2	IPR016554
Domain	RunxI	RUNX2 RUNX1	2.28e-05	3	52	2	PF08504
Domain	AML1_Runt	RUNX2 RUNX1	2.28e-05	3	52	2	IPR000040
Domain	EGF_3	CD248 MUC17 VASN LRP1 C1S LTBP4	4.67e-05	235	52	6	PS50026
Domain	IPT	NFATC1 PLXNA4 PKHD1L1	5.68e-05	27	52	3	SM00429
Domain	EGF-like_dom	CD248 MUC17 VASN LRP1 C1S LTBP4	6.44e-05	249	52	6	IPR000742
Domain	EGF_1	CD248 MUC17 VASN LRP1 C1S LTBP4	7.35e-05	255	52	6	PS00022
Domain	EGF-like_CS	CD248 MUC17 VASN LRP1 C1S LTBP4	8.35e-05	261	52	6	IPR013032
Domain	TIG	NFATC1 PLXNA4 PKHD1L1	8.66e-05	31	52	3	PF01833
Domain	EGF_2	CD248 MUC17 VASN LRP1 C1S LTBP4	9.08e-05	265	52	6	PS01186
Domain	IPT	NFATC1 PLXNA4 PKHD1L1	9.54e-05	32	52	3	IPR002909
Domain	EGF_CA	CD248 LRP1 C1S LTBP4	9.58e-05	86	52	4	PF07645
Domain	p53/RUNT-type_TF_DNA-bd	RUNX2 RUNX1	1.13e-04	6	52	2	IPR012346
Domain	-	RUNX2 RUNX1	1.13e-04	6	52	2	2.60.40.720
Domain	EGF_Ca-bd_CS	CD248 LRP1 C1S LTBP4	1.53e-04	97	52	4	IPR018097
Domain	EGF_CA	CD248 LRP1 C1S LTBP4	1.65e-04	99	52	4	PS01187
Domain	EGF-type_Asp/Asn_hydroxyl_site	CD248 LRP1 C1S LTBP4	2.15e-04	106	52	4	IPR000152
Domain	EGF_CA	CD248 LRP1 C1S LTBP4	3.68e-04	122	52	4	SM00179
Domain	EGF-like_Ca-bd_dom	CD248 LRP1 C1S LTBP4	3.92e-04	124	52	4	IPR001881
Domain	EGF	CD248 VASN LRP1 C1S	4.16e-04	126	52	4	PF00008
Domain	p53-like_TF_DNA-bd	NFATC1 RUNX2 RUNX1	4.32e-04	53	52	3	IPR008967
Domain	EGF	CD248 MUC17 VASN LRP1 LTBP4	4.85e-04	235	52	5	SM00181
Domain	Growth_fac_rcpt_	CD248 LRP1 PCSK4 LTBP4	9.28e-04	156	52	4	IPR009030
Domain	ASX_HYDROXYL	LRP1 C1S LTBP4	2.72e-03	100	52	3	PS00010
Domain	Ig_E-set	NFATC1 PLXNA4 PKHD1L1	3.04e-03	104	52	3	IPR014756
Domain	LDLR_class-A_CS	LRP1 LDLRAD4	5.54e-03	40	52	2	IPR023415
Domain	PH_dom-like	PRKD3 MAPK8IP1 PDPK1 EPS8L3 PLEKHA6	6.50e-03	426	52	5	IPR011993
Domain	Ldl_recept_a	LRP1 LDLRAD4	6.97e-03	45	52	2	PF00057
Domain	-	LRP1 LDLRAD4	7.28e-03	46	52	2	4.10.400.10
Domain	LDLRA_1	LRP1 LDLRAD4	7.90e-03	48	52	2	PS01209
Domain	LDLRA_2	LRP1 LDLRAD4	8.22e-03	49	52	2	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LDLRAD4	8.22e-03	49	52	2	IPR002172
Domain	LDLa	LRP1 LDLRAD4	8.22e-03	49	52	2	SM00192
Domain	SUSHI	CD248 C1S	1.06e-02	56	52	2	PS50923
Domain	Sushi_SCR_CCP_dom	CD248 C1S	1.10e-02	57	52	2	IPR000436
Pathway	KEGG_MTOR_SIGNALING_PATHWAY	PDPK1 TSC1 ULK1 ULK2	1.23e-05	52	39	4	M7561
Pathway	BIOCARTA_MTOR_PATHWAY	PDPK1 EIF4G1 TSC1	2.91e-05	22	39	3	M16563
Pathway	WP_NANOPARTICLE_TRIGGERED_AUTOPHAGIC_CELL_DEATH	TSC1 ULK1 ULK2	3.34e-05	23	39	3	M39325
Pathway	PID_MTOR_4PATHWAY	PDPK1 TSC1 ULK1 ULK2	3.80e-05	69	39	4	M121
Pathway	REACTOME_RUNX2_REGULATES_CHONDROCYTE_MATURATION	GLI2 RUNX2	7.42e-05	5	39	2	M27804
Pathway	WP_TARGET_OF_RAPAMYCIN_SIGNALING	TSC1 ULK1 ULK2	1.31e-04	36	39	3	M39635
Pathway	REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS	RUNX2 RUNX1	1.55e-04	7	39	2	M27799
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	5.44e-25	25	59	11	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	9.92e-23	23	59	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	FAM90A14 FAM90A17 VASN FAM90A19 FAM90A22 FAM90A26 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A10	4.20e-15	164	59	11	22967998
Pubmed	Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway.	EIF4EBP3 RUNX2 RUNX1	1.62e-07	7	59	3	21088106
Pubmed	Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).	ULK1 ULK2	2.83e-06	2	59	2	30782972
Pubmed	RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells.	RUNX2 RUNX1	2.83e-06	2	59	2	32180230
Pubmed	The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.	RUNX2 RUNX1	2.83e-06	2	59	2	9233771
Pubmed	Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.	RUNX2 RUNX1	2.83e-06	2	59	2	17290219
Pubmed	Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.	ULK1 ULK2	2.83e-06	2	59	2	9600096
Pubmed	Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes.	ULK1 ULK2	2.83e-06	2	59	2	24135897
Pubmed	Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.	RUNX2 RUNX1	2.83e-06	2	59	2	35551452
Pubmed	The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy.	ULK1 ULK2	2.83e-06	2	59	2	21460635
Pubmed	Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes.	ULK1 ULK2	2.83e-06	2	59	2	33149253
Pubmed	Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.	RUNX2 RUNX1	2.83e-06	2	59	2	23321257
Pubmed	ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.	ULK1 ULK2	2.83e-06	2	59	2	27153534
Pubmed	TLE3, transducing-like enhancer of split 3, suppresses osteoblast differentiation of bone marrow stromal cells.	TLE3 RUNX2	2.83e-06	2	59	2	23880346
Pubmed	Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.	ULK1 ULK2	2.83e-06	2	59	2	23291478
Pubmed	Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.	RUNX2 RUNX1	2.83e-06	2	59	2	17533052
Pubmed	A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.	RUNX2 RUNX1	2.83e-06	2	59	2	27634876
Pubmed	Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle.	ULK1 ULK2	2.83e-06	2	59	2	34658916
Pubmed	A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons.	ULK1 ULK2	2.83e-06	2	59	2	10624947
Pubmed	Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.	RUNX2 RUNX1	2.83e-06	2	59	2	16059634
Pubmed	Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene.	RUNX2 RUNX1	2.83e-06	2	59	2	10903914
Pubmed	Heritability and genetic association analysis of cognition in the Diabetes Heart Study.	TLE3 PLXNA4 RALGAPA2	6.03e-06	21	59	3	24684796
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	SF3B1 AP2A1 TLE3 AMOTL1 SRSF11	6.58e-06	154	59	5	16055720
Pubmed	Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors.	RUNX2 RUNX1	8.48e-06	3	59	2	19585539
Pubmed	Long non‑coding RNA growth arrest‑specific 5 (GAS5) acts as a tumor suppressor by promoting autophagy in breast cancer.	ULK1 ULK2	8.48e-06	3	59	2	32705220
Pubmed	Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development.	RUNX2 RUNX1	8.48e-06	3	59	2	14516670
Pubmed	Ammonia-induced autophagy is independent of ULK1/ULK2 kinases.	ULK1 ULK2	8.48e-06	3	59	2	21690395
Pubmed	Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection.	RUNX2 RUNX1	8.48e-06	3	59	2	12218099
Pubmed	Mutations and karyotype in myelodysplastic syndromes: TP53 clusters with monosomal karyotype, RUNX1 with trisomy 21, and SF3B1 with inv(3)(q21q26.2) and del(11q).	SF3B1 RUNX1	8.48e-06	3	59	2	29249799
Pubmed	Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.	GLI2 RUNX2	8.48e-06	3	59	2	17442891
Pubmed	Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function.	ULK1 ULK2	8.48e-06	3	59	2	35104184
Pubmed	RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region.	RUNX2 RUNX1	8.48e-06	3	59	2	16237704
Pubmed	Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer.	ULK1 ULK2	8.48e-06	3	59	2	39213022
Pubmed	Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells.	ULK1 ULK2	8.48e-06	3	59	2	26213203
Pubmed	ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer.	ULK1 ULK2	8.48e-06	3	59	2	32516362
Pubmed	Serine 389 phosphorylation of 3-phosphoinositide-dependent kinase 1 by UNC-51-like kinase 1 affects its ability to regulate Akt and p70 S6kinase.	PDPK1 ULK1	8.48e-06	3	59	2	32317083
Pubmed	The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).	RUNX2 RUNX1	8.48e-06	3	59	2	8384306
Pubmed	The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.	RUNX2 RUNX1	8.48e-06	3	59	2	12217689
Pubmed	AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.	RUNX2 RUNX1	8.48e-06	3	59	2	7835892
Pubmed	Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.	RUNX2 RUNX1	8.48e-06	3	59	2	15713794
Pubmed	Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.	RUNX2 RUNX1	8.48e-06	3	59	2	22032690
Pubmed	An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.	ULK1 ULK2	8.48e-06	3	59	2	37846507
Pubmed	Genetic regulation of the RUNX transcription factor family has antitumor effects.	RUNX2 RUNX1	8.48e-06	3	59	2	28530640
Pubmed	Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor.	RUNX2 RUNX1	8.48e-06	3	59	2	8497254
Pubmed	FNDC5/irisin facilitates muscle-adipose-bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2.	RUNX2 RUNX1	8.48e-06	3	59	2	35124008
Pubmed	Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2.	RUNX2 RUNX1	8.48e-06	3	59	2	15051730
Pubmed	AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene.	RUNX2 RUNX1	8.48e-06	3	59	2	10521447
Pubmed	Identification and comparative analysis of a second runx3 promoter.	RUNX2 RUNX1	8.48e-06	3	59	2	11483356
Pubmed	PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.	RUNX2 RUNX1	8.48e-06	3	59	2	8035830
Pubmed	RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.	RUNX2 RUNX1	8.48e-06	3	59	2	19020999
Pubmed	SF3B1, RUNX1 and TP53 Mutations Significantly Impact the Outcome of Patients With Lower-Risk Myelodysplastic Syndrome.	SF3B1 RUNX1	8.48e-06	3	59	2	36117041
Pubmed	Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators.	RUNX2 RUNX1	1.69e-05	4	59	2	29107070
Pubmed	A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.	RUNX2 RUNX1	1.69e-05	4	59	2	10228168
Pubmed	Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity.	TSC1 ULK1	1.69e-05	4	59	2	36398408
Pubmed	Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy.	ULK1 ULK2	1.69e-05	4	59	2	25925668
Pubmed	Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis.	RUNX2 RUNX1	1.69e-05	4	59	2	20236534
Pubmed	AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite element.	RUNX2 RUNX1	1.69e-05	4	59	2	11274169
Pubmed	ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function.	RUNX2 RUNX1	1.69e-05	4	59	2	9119228
Pubmed	Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse.	RUNX2 RUNX1	1.69e-05	4	59	2	26001080
Pubmed	ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.	ULK1 ULK2	1.69e-05	4	59	2	30979586
Pubmed	Dual color FISH on CBF primary acute myeloid leukemia.	RUNX2 RUNX1	1.69e-05	4	59	2	20306685
Pubmed	Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death.	ULK1 ULK2	1.69e-05	4	59	2	21475306
Pubmed	The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.	RUNX2 RUNX1	1.69e-05	4	59	2	25185713
Pubmed	Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.	RUNX2 RUNX1	1.69e-05	4	59	2	12807883
Pubmed	FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.	ULK1 ULK2	1.69e-05	4	59	2	18443221
Pubmed	Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation.	RUNX2 RUNX1	1.69e-05	4	59	2	11641401
Pubmed	Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.	RUNX2 RUNX1	1.69e-05	4	59	2	12464175
Pubmed	Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.	RUNX2 RUNX1	1.69e-05	4	59	2	8437866
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	TSC22D1 GLI2 RUNX2 LHX8 RUNX1	1.87e-05	191	59	5	24146773
Pubmed	Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma.	ULK1 ULK2	2.82e-05	5	59	2	32203415
Pubmed	Oncogenic Runx1-Myc axis in p53-deficient thymic lymphoma.	RUNX2 RUNX1	2.82e-05	5	59	2	35114276
Pubmed	Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles.	PDPK1 TSC1	2.82e-05	5	59	2	19843540
Pubmed	Atg101, a novel mammalian autophagy protein interacting with Atg13.	ULK1 ULK2	2.82e-05	5	59	2	19597335
Pubmed	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.	RUNX2 RUNX1	2.82e-05	5	59	2	11965546
Pubmed	Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma.	RUNX2 RUNX1	2.82e-05	5	59	2	34803166
Pubmed	Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3.	RUNX2 RUNX1	2.82e-05	5	59	2	20484411
Pubmed	Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death.	ULK1 ULK2	2.82e-05	5	59	2	22493260
Pubmed	Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.	PDPK1 RUNX2	2.82e-05	5	59	2	22133875
Pubmed	Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues.	RUNX2 RUNX1	2.82e-05	5	59	2	9794229
Pubmed	MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development.	MAML1 RUNX2	2.82e-05	5	59	2	23326237
Pubmed	Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development.	RUNX2 RUNX1	2.82e-05	5	59	2	7862157
Pubmed	Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1.	RUNX2 RUNX1	2.82e-05	5	59	2	17377532
Pubmed	Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac.	RUNX2 RUNX1	2.82e-05	5	59	2	27802172
Pubmed	A role for BCL2L13 and autophagy in germline purifying selection of mtDNA.	ULK1 ULK2	2.82e-05	5	59	2	36608143
Pubmed	The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.	ULK1 ULK2	2.82e-05	5	59	2	27203176
Pubmed	Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.	PDPK1 ULK1	2.82e-05	5	59	2	26593251
Pubmed	Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter.	RUNX2 RUNX1	2.82e-05	5	59	2	12551949
Pubmed	Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis.	GLI2 RUNX2	2.82e-05	5	59	2	21151991
Pubmed	Possible roles of Runx1 and Sox9 in incipient intramembranous ossification.	RUNX2 RUNX1	4.23e-05	6	59	2	15355562
Pubmed	Role of Unc51.1 and its binding partners in CNS axon outgrowth.	ULK1 ULK2	4.23e-05	6	59	2	15014045
Pubmed	Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.	RUNX2 RUNX1	4.23e-05	6	59	2	24677539
Pubmed	Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development.	RUNX2 RUNX1	4.23e-05	6	59	2	15389629
Pubmed	Upstream and downstream of mTOR.	EIF4G1 TSC1	4.23e-05	6	59	2	15314020
Pubmed	Annexin A2 Regulates Autophagy in Pseudomonas aeruginosa Infection through the Akt1-mTOR-ULK1/2 Signaling Pathway.	ULK1 ULK2	4.23e-05	6	59	2	26371245
Pubmed	The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.	ULK1 ULK2	4.23e-05	6	59	2	27046250
Pubmed	The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.	NFATC1 TSC1	4.23e-05	6	59	2	31289211
Pubmed	The essential requirement for Runx1 in the development of the sternum.	RUNX2 RUNX1	4.23e-05	6	59	2	20152828
Pubmed	Activation of Akt/PDK signaling in macrophages upon binding of receptor-recognized forms of alpha2-macroglobulin to its cellular receptor: effect of silencing the CREB gene.	PDPK1 LRP1	4.23e-05	6	59	2	15389876
Cytoband	8p23.1	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.03e-16	154	59	11	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.07e-14	234	59	11	chr8p23
GeneFamily	Autophagy related	ULK1 ULK2	1.02e-03	33	26	2	1022
Coexpression	DESCARTES_FETAL_THYMUS_STROMAL_CELLS	SSC5D CD248 LRP1 C1S LTBP4 ADAMTSL4	2.12e-07	137	49	6	M40313
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_DN	NFATC1 TLE3 NACA EIF4G1 SRSF11 RUNX2 RUNX1	5.25e-07	260	49	7	M41075
Coexpression	BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B	MAPK8IP1 ZBTB49 TRIM11 VASN AMOTL1 LRP1 ULK1 LTBP4	7.97e-06	554	49	8	M2244
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP	PRKD3 TSC22D1 SF3B1 CD248 TSC1	3.57e-05	200	49	5	M4524
Coexpression	WOOD_EBV_EBNA1_TARGETS_UP	SF3B1 EIF4G1 MAML1 C1S	5.38e-05	110	49	4	M1696
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	SF3B1 TLE3 PDPK1 AMOTL1 EIF4G1 LRP1 C1S SRSF11 TSC1 RUNX1 LTBP4	1.03e-06	801	47	11	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1	NFATC1 CDHR5 RUNX1 PKHD1L1 LDLRAD4	2.12e-05	152	47	5	ratio_MESO_vs_SC_1000_K1
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	SF3B1 PDPK1 EIF4G1 LRP1 C1S SRSF11 RUNX1	3.22e-05	413	47	7	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	SF3B1 TLE3 PDPK1 EIF4G1 LRP1 C1S SRSF11 TSC1 LTBP4	4.99e-05	790	47	9	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	SF3B1 PDPK1 AMOTL1 EIF4G1 LRP1 C1S SRSF11 TSC1 LTBP4	5.45e-05	799	47	9	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100	RUNX2 RUNX1 PCSK4 LDLRAD4	6.28e-05	97	47	4	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_100
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	SF3B1 TLE3 PDPK1 EIF4G1 SRSF11 TSC1	7.51e-05	323	47	6	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500	CD248 GLI2 PLXNA4 LRP1 RUNX1 LTBP4	1.63e-04	372	47	6	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	SF3B1 PDPK1 EIF4G1 PLXNA4 SRSF11 TSC1 LHX8 RUNX1	2.59e-04	770	47	8	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	SF3B1 PDPK1 EIF4G1 LRP1 SRSF11 LTBP4	2.61e-04	406	47	6	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	SF3B1 PDPK1 EIF4G1 SRSF11 TSC1 LHX8 RUNX1 LTBP4	2.77e-04	778	47	8	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	PDPK1 EIF4G1 SRSF11 TSC1 RUNX1	3.45e-04	275	47	5	gudmap_developingGonad_e14.5_ epididymis_1000_k3
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN AMOTL1 EIF4EBP3 LRP1 C1S C1orf159 CCDC51	2.74e-11	185	49	8	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN AMOTL1 EIF4EBP3 LRP1 C1S C1orf159 CCDC51	2.74e-11	185	49	8	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 VASN LRP1 C1S LTBP4	6.11e-08	189	49	6	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	6.11e-08	189	49	6	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SSC5D GLI2 PLXNA4 LRP1 ADAMTSL4 LDLRAD4	6.11e-08	189	49	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 VASN LRP1 C1S LTBP4	6.50e-08	191	49	6	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 VASN LRP1 C1S LTBP4	6.91e-08	193	49	6	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 VASN LRP1 C1S LTBP4	6.91e-08	193	49	6	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 VASN LRP1 C1S LTBP4	7.81e-08	197	49	6	c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SSC5D CD248 GLI2 LRP1 C1S LTBP4	8.54e-08	200	49	6	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	db6281b5d4032116310db379d9175d790994c99c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SSC5D CD248 LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	SSC5D CD248 PLXNA4 LRP1 RUNX2 LTBP4	8.54e-08	200	49	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SSC5D CD248 GLI2 LRP1 C1S LTBP4	8.54e-08	200	49	6	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SSC5D CD248 LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	cbf6a6c3db88bac37bd084a3a914b12b3af524eb
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD248 VASN LRP1 C1S LTBP4 ADAMTSL4	8.54e-08	200	49	6	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SSC5D ULK1 PLEKHA6 ULK2 ADAMTSL4	6.74e-07	151	49	5	45392bb1c6358beff33da0ca84f7696fb5824f30
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SSC5D ULK1 PLEKHA6 ULK2 ADAMTSL4	6.74e-07	151	49	5	3d861285c71abe220b19a069eb9876199c6c8f39
ToppCell	Mild_COVID-19-Myeloid-TRAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SSC5D ULK1 PLEKHA6 ULK2 ADAMTSL4	7.43e-07	154	49	5	ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD248 GLI2 LRP1 C1S LTBP4	1.36e-06	174	49	5	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD248 GLI2 LRP1 C1S LTBP4	1.36e-06	174	49	5	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SSC5D GLI2 PLXNA4 LRP1 LTBP4	1.56e-06	179	49	5	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	droplet-Limb_Muscle-nan-21m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S LTBP4	1.69e-06	182	49	5	a51cbdb8d6528a82044be838c70c492fc6370891
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	EIF4EBP3 C1S RALGAPA2 PKHD1L1 ULK2	1.69e-06	182	49	5	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 LRP1 C1S LTBP4	1.69e-06	182	49	5	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 VASN C1S LTBP4	1.74e-06	183	49	5	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 VASN C1S LTBP4	1.79e-06	184	49	5	4a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S LTBP4	1.79e-06	184	49	5	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S LTBP4	1.83e-06	185	49	5	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S LTBP4	1.83e-06	185	49	5	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SSC5D PLXNA4 LRP1 RUNX2 LTBP4	1.83e-06	185	49	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SSC5D PLXNA4 C1S LTBP4 LDLRAD4	1.83e-06	185	49	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NFATC1 GLI2 AMOTL1 PLXNA4 LDLRAD4	1.83e-06	185	49	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D GLI2 LRP1 C1S LTBP4	1.83e-06	185	49	5	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D GLI2 LRP1 C1S LTBP4	1.83e-06	185	49	5	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D GLI2 LRP1 C1S LTBP4	1.88e-06	186	49	5	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN C1S LTBP4 ADAMTSL4	1.93e-06	187	49	5	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S LTBP4	1.98e-06	188	49	5	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SSC5D CD248 LRP1 LTBP4 ADAMTSL4	1.98e-06	188	49	5	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.04e-06	189	49	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S LTBP4	2.04e-06	189	49	5	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK8IP1 NFATC1 C1S RUNX1 LTBP4	2.04e-06	189	49	5	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.04e-06	189	49	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	SSC5D GLI2 AMOTL1 PLXNA4 LDLRAD4	2.09e-06	190	49	5	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S LTBP4	2.09e-06	190	49	5	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.14e-06	191	49	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 VASN C1S LTBP4	2.14e-06	191	49	5	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SSC5D CD248 GLI2 C1S LTBP4	2.14e-06	191	49	5	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SSC5D GLI2 PLXNA4 ADAMTSL4 LDLRAD4	2.14e-06	191	49	5	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.20e-06	192	49	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.20e-06	192	49	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S PLEKHA6	2.20e-06	192	49	5	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D VASN LRP1 C1S RUNX1	2.20e-06	192	49	5	b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 GLI2 C1S LTBP4	2.20e-06	192	49	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.20e-06	192	49	5	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 GLI2 C1S LTBP4	2.20e-06	192	49	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 VASN LRP1 C1S	2.20e-06	192	49	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.20e-06	192	49	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 GLI2 C1S LTBP4	2.20e-06	192	49	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.20e-06	192	49	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.20e-06	192	49	5	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.20e-06	192	49	5	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.20e-06	192	49	5	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S PLEKHA6	2.20e-06	192	49	5	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.20e-06	192	49	5	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.20e-06	192	49	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S ADAMTSL4	2.26e-06	193	49	5	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SSC5D CD248 LRP1 C1S LTBP4	2.26e-06	193	49	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	facs-MAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 AMOTL1 LRP1 C1S LTBP4	2.26e-06	193	49	5	733f557bdc80293b40ccdf560f1675793df932d6
ToppCell	facs-MAT-Fat-24m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 AMOTL1 LRP1 C1S LTBP4	2.26e-06	193	49	5	eb3c46b6fb06dc8708dc3032189b47ed93ee2357
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.26e-06	193	49	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.26e-06	193	49	5	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D CD248 LRP1 C1S ADAMTSL4	2.26e-06	193	49	5	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.26e-06	193	49	5	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SSC5D CD248 LRP1 C1S LTBP4	2.26e-06	193	49	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	facs-MAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 AMOTL1 LRP1 C1S LTBP4	2.26e-06	193	49	5	b45cd02081f97904eaea2d013e1fa980505d060b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.31e-06	194	49	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.31e-06	194	49	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.31e-06	194	49	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI2 PLXNA4 LRP1 C1S LTBP4	2.31e-06	194	49	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.37e-06	195	49	5	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD248 VASN LRP1 C1S LTBP4	2.37e-06	195	49	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFATC1 CD248 VASN LRP1 C1S	2.37e-06	195	49	5	0feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCell	Mesenchymal_cells-Endosteal_fibro.\|World / Lineage and Cell class	CD248 VASN LRP1 LTBP4 ADAMTSL4	2.37e-06	195	49	5	d53974d1866e23c894ffd492ea11d20422919b11
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFATC1 CD248 VASN LRP1 C1S	2.37e-06	195	49	5	2a6f67875cef140b0e6b8401436719675c6b3665
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D CD248 LRP1 C1S LTBP4	2.37e-06	195	49	5	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.37e-06	195	49	5	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	facs-Trachea-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S LTBP4	2.37e-06	195	49	5	0d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VASN GLI2 LRP1 C1S LTBP4	2.43e-06	196	49	5	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.43e-06	196	49	5	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD248 VASN LRP1 C1S RUNX1	2.43e-06	196	49	5	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 LRP1 C1S RUNX2 LTBP4	2.43e-06	196	49	5	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD248 VASN LRP1 C1S RUNX1	2.43e-06	196	49	5	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	MatrixFB-Fibroblast-B_(Myofibroblast)\|MatrixFB / shred on cell class and cell subclass (v4)	SSC5D TSC22D1 CD248 PLXNA4 RUNX1	2.43e-06	196	49	5	38ea0eaf42f95c321ca23570d0d7752980cf00f8
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A	WHRN CD248 PLEKHA6 RUNX1 LDLRAD4 PYHIN1	3.76e-06	195	49	6	3834_UP
Drug	NSC226080	PRKD3 VASN PDPK1 CNTN5 EIF4G1 EIF4EBP3 LRP1 TSC1 ULK1	3.80e-05	782	49	9	CID000005040
Drug	Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A	MAML1 SRSF11 PLEKHA6 RUNX1 LTBP4	4.55e-05	183	49	5	3480_UP
Drug	Colchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A	WHRN MAML1 RUNX1 LTBP4 ADAMTSL4	5.30e-05	189	49	5	5675_UP
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	GLI2 LRP1 ULK1 RUNX2 RUNX1	5.85e-05	193	49	5	4466_UP
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A	WHRN LTBP4 ADAMTSL4 LDLRAD4 PYHIN1	6.00e-05	194	49	5	3900_UP
Drug	(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A	EPS8L3 RUNX2 RUNX1 LTBP4 LDLRAD4	6.15e-05	195	49	5	3789_UP
Drug	Aminocaproic acid [60-32-2]; Up 200; 30.4uM; HL60; HT_HG-U133A	NFATC1 C1orf159 RUNX2 KLHDC4 ADAMTSL4	6.30e-05	196	49	5	3122_UP
Drug	Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A	WHRN MAML1 C1orf159 LTBP4 ULK2	6.45e-05	197	49	5	3215_DN
Drug	haloperidol; Down 200; 10uM; PC3; HT_HG-U133A	LRP1 C1orf159 RUNX1 LTBP4 ULK2	6.61e-05	198	49	5	4468_DN
Drug	Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A	WHRN GLI2 CNTN5 RUNX2 RUNX1	6.61e-05	198	49	5	5416_UP
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	GLI2 LRP1 C1S RUNX1 LDLRAD4	6.61e-05	198	49	5	5087_UP
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A	EPS8L3 RUNX1 LTBP4 ADAMTSL4 LDLRAD4	6.77e-05	199	49	5	4311_UP
Disease	overall survival, pancreatic carcinoma	WHRN RUNX2 LDLRAD4	6.21e-05	49	46	3	EFO_0000638, EFO_0002618
Disease	Glioblastoma Multiforme	PRKD3 RUNX1 LTBP4	6.99e-04	111	46	3	C1621958
Disease	Hematopoetic Myelodysplasia	SF3B1 RUNX1	9.40e-04	29	46	2	C2713368
Disease	progressive supranuclear palsy	TRIM11 RUNX2	1.07e-03	31	46	2	MONDO_0019037
Disease	cognition	TLE3 PLXNA4	1.45e-03	36	46	2	EFO_0003925
Disease	spleen volume	CNTN5 PLEKHA6	2.06e-03	43	46	2	EFO_0600047
Disease	hip geometry	RUNX2 RUNX1	2.16e-03	44	46	2	EFO_0004685
Disease	complement factor H-related protein 3 measurement	SSC5D NFATC1 PLEKHA6	2.34e-03	169	46	3	EFO_0600056
Disease	Rheumatoid Arthritis	TLE3 RUNX2 RUNX1	2.54e-03	174	46	3	C0003873
Disease	atrial fibrillation	NFATC1 TLE3 CNTN5 NACA	2.65e-03	371	46	4	EFO_0000275

Protein segments in the cluster

Peptide	Gene	Start	Entry
GTGQSCPTGSRPPDM	ADAMTSL4	886	Q6UY14
MPPRGSLTGVQTCRT	CD248	741	Q9HCU0
MSTSTSCPIPGGRDQ	EIF4EBP3	1	O60516
NGGMEPTPSTVSTPS	AP2A1	641	O95782
GVTSRPCQLPFPSTM	AMOTL1	371	Q8IY63
GTSQPMPPGVGTSTS	CDHR5	546	Q9HBB8
GPSTSPQMGRRTPAQ	FAM90A10	341	A6NDY2
TNPIGTGDPSTPSRM	CNTN5	751	O94779
GPSTSPQMGRRTPAQ	FAM90A7	341	A6NKC0
GPSTSPQMGRRTPAQ	FAM90A23	341	A8MXZ1
PGMNTLGPSNSSCPR	MAML1	696	Q92585
PCRRSTATQMAPPGG	MAPK8IP1	236	Q9UQF2
SGMPTCRCPTGFTGP	LRP1	4251	Q07954
GPSTSPQMGRRTPAQ	FAM90A22	341	A8MWA6
GPSTSPQMGRRTPAQ	FAM90A14	341	P0C7W9
GSCMGPTTPDSRPRL	PCSK4	681	Q6UW60
PSRGPMSGGTQVTIT	PLXNA4	961	Q9HCM2
TPGTQGQSPSRVPML	EPS8L3	511	Q8TE67
CPQRSTLMPAAPGVS	NFATC1	751	O95644
LMPVTPQASVCTSPG	PRKD3	531	O94806
SSSPRSMASGSGCPP	LHX8	56	Q68G74
RQPVAGSQCPGMTTT	GLI2	1226	P10070
GPSTSPQMGRRTPAQ	FAM90A17	341	P0DV74
VPGFPAVMSSRGPCT	RALGAPA2	156	Q2PPJ7
GPSTSPQMGRRTPAQ	FAM90A16	341	P0DV73
GPSTSPQMGRRTPAQ	FAM90A19	341	P0DV76
GPSTSPQMGRRTPAQ	FAM90A8	341	A6NJQ4
TPGGPTKPTSSSCMD	E2F8	826	A0AVK6
GASTSTAMGRSPPPQ	PYHIN1	166	Q6K0P9
MGPTVSPICLPGTSS	C1S	541	P09871
IMSGARTASTPTPPQ	EIF4G1	196	Q04637
DPMTGRCVPPRTSAG	LTBP4	1126	Q8N2S1
TGPTPRSGCQMSVTP	KLHDC4	226	Q8TBB5
MIPPPQSSGNSSCRI	C1orf159	196	Q96HA4
GPSTSPQMGRRTPAQ	FAM90A5P	341	A8MXJ8
QCSPREGPASTPMSS	CCDC24	286	Q8N4L8
GPSTSPQMGRRTPAQ	FAM90A24P	341	P0C7X0
GTSMPNSTPSEGTTP	MUC17	1736	Q685J3
PATPISPGRASGMTT	RUNX1	271	Q01196
GGDRSPSRMLPPCTT	RUNX2	461	Q13950
PSRMLPPCTTTSNGS	RUNX2	466	Q13950
FMTRTLCSPGPSQPG	CCDC51	31	Q96ER9
PSMVRTQTESSTPPG	PDPK1	26	O15530
GPSTSPQMGRRTPAQ	FAM90A12P	341	A8MX19
GPSTSPQMGRRTPAQ	FAM90A9	341	A6NNJ1
GPSTSPQMGRRTPAQ	FAM90A13P	341	P0C7W8
GPSTSPQMGRRTPAQ	FAM90A26	341	D6RGX4
DLQPPSSMPSCSGTV	WHRN	606	Q9P202
VSSTGPSGMPSAPTN	TSC22D1	836	Q15714
PPSTMTSQAPGTAGV	SSC5D	431	A1L4H1
GPSTSPQMGRRTPAQ	FAM90A15P	341	P0C7V4
GRMLSVQCATPSPPT	PLEKHA6	1006	Q9Y2H5
MVCGMTTPPTSPGNV	TSC1	351	Q92574
SSSPTPMTICRPKGG	TRIM11	446	Q96F44
MSNTTVVPSTAGPGP	SRSF11	1	Q05519
TPASQMGGSTPVLTP	SF3B1	341	O75533
FPMQTGSCTSTVPAP	PKHD1L1	2631	Q86WI1
APTPGTSTTPGLRSM	TLE3	326	Q04726
CESQMGQGTRPSPTP	VASN	441	Q6EMK4
TSPMGFLRPGSCSPV	ULK2	441	Q8IYT8
TVVQPPGMPCNSTLS	ZBTB49	121	Q6ZSB9
SGSTPPQGPRTRMFS	ULK1	761	O75385
GPSTSPQMGRRTPAQ	FAM90A18	341	P0DV75
TCSSNGRMEGPPPTY	LDLRAD4	241	O15165
TCVSPPMSSGPISNI	NACA	461	E9PAV3