Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

2.02e-0849716GO:0140359
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

4.54e-0828715GO:0140326
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP13A4 ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

1.19e-07109717GO:0042626
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

1.02e-0651715GO:0140303
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP13A4 ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

3.27e-06178717GO:0015399
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 ABCA12 ABCA13 DDX60 DNAH9 ABCA7

3.46e-064417110GO:0016887
GeneOntologyMolecularFunctionlipid transporter activity

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7 SLC27A4

6.17e-06196717GO:0005319
GeneOntologyMolecularFunctionATP-dependent activity

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 ABCA12 ABCA13 DDX60 DNAH9 ABCA7 SLC27A4

1.02e-056147111GO:0140657
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 CILP ABCA12 ABCA13 DDX60 DNAH9 ABCA7

1.72e-048397111GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 CILP ABCA12 ABCA13 DDX60 DNAH9 ABCA7

1.74e-048407111GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 CILP ABCA12 ABCA13 DDX60 DNAH9 ABCA7

1.74e-048407111GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP13A4 ABCA2 ABCA3 ABCA4 DHX58 ABCA12 ABCA13 DDX60 DNAH9 ABCA7

3.97e-047757110GO:0017111
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ABCA3 ABCA4

1.10e-0314712GO:0140333
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ABCA7

1.45e-0316712GO:0140328
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP13A4 ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

1.51e-03477717GO:0022804
GeneOntologyMolecularFunctionflippase activity

ABCA3 ABCA4

1.64e-0317712GO:0140327
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCA4 ABCA12 SLC27A4

2.24e-0373713GO:0170055
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA3 ABCA7

2.27e-0320712GO:0008525
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCA3 ABCA4 ABCA7

2.33e-0374713GO:0005548
GeneOntologyBiologicalProcesslipid translocation

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

1.97e-0660715GO:0034204
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

2.95e-0665715GO:0097035
GeneOntologyBiologicalProcessregulation of cholesterol transport

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

9.87e-0683715GO:0032374
GeneOntologyBiologicalProcessregulation of sterol transport

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

9.87e-0683715GO:0032371
GeneOntologyBiologicalProcesspositive regulation of sterol transport

ABCA3 ABCA12 ABCA13 ABCA7

1.07e-0540714GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

ABCA3 ABCA12 ABCA13 ABCA7

1.07e-0540714GO:0032376
GeneOntologyBiologicalProcessphospholipid efflux

ABCA3 ABCA12 ABCA7

1.73e-0515713GO:0033700
GeneOntologyBiologicalProcessceramide transport

ABCA2 ABCA12 ABCA13

3.07e-0518713GO:0035627
GeneOntologyBiologicalProcessregulation of cholesterol efflux

ABCA2 ABCA3 ABCA12 ABCA7

4.14e-0556714GO:0010874
GeneOntologyBiologicalProcessregulation of RIG-I signaling pathway

DHX58 RNF125 DDX60

4.97e-0521713GO:0039535
GeneOntologyBiologicalProcessregulation of phospholipid efflux

ABCA3 ABCA7

6.98e-054712GO:1902994
GeneOntologyBiologicalProcesspositive regulation of phospholipid efflux

ABCA3 ABCA7

6.98e-054712GO:1902995
GeneOntologyBiologicalProcesspositive regulation of MDA-5 signaling pathway

DHX58 DDX60

6.98e-054712GO:1900245
GeneOntologyBiologicalProcesscholesterol transport

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

9.91e-05134715GO:0030301
GeneOntologyBiologicalProcesspositive regulation of cholesterol efflux

ABCA3 ABCA12 ABCA7

1.08e-0427713GO:0010875
GeneOntologyBiologicalProcesssterol transport

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

1.18e-04139715GO:0015918
GeneOntologyBiologicalProcesscholesterol efflux

ABCA2 ABCA3 ABCA12 ABCA7

1.44e-0477714GO:0033344
GeneOntologyBiologicalProcessRIG-I signaling pathway

DHX58 RNF125 DDX60

1.48e-0430713GO:0039529
GeneOntologyBiologicalProcessregulation of MDA-5 signaling pathway

DHX58 DDX60

2.43e-047712GO:0039533
GeneOntologyBiologicalProcessregulation of postsynaptic membrane neurotransmitter receptor levels

VAC14 GRIPAP1 HIP1 KALRN NBEA

2.55e-04164715GO:0099072
GeneOntologyBiologicalProcessregulation of protein localization to synapse

GRIPAP1 KALRN NBEA

3.02e-0438713GO:1902473
GeneOntologyBiologicalProcessregulation of protein localization to cell periphery

GRIPAP1 ABCA2 KALRN NBEA HECTD1

3.09e-04171715GO:1904375
GeneOntologyBiologicalProcessnegative regulation of RIG-I signaling pathway

DHX58 RNF125

3.23e-048712GO:0039536
GeneOntologyBiologicalProcessregulation of receptor localization to synapse

GRIPAP1 KALRN NBEA

3.27e-0439713GO:1902683
GeneOntologyBiologicalProcessregulation of lipid transport

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

3.81e-04179715GO:0032368
GeneOntologyBiologicalProcesspositive regulation of lipid transport

ABCA3 ABCA12 ABCA13 ABCA7

4.25e-04102714GO:0032370
GeneOntologyBiologicalProcessphospholipid transport

ABCA3 ABCA4 ABCA12 ABCA7

4.91e-04106714GO:0015914
GeneOntologyBiologicalProcessMDA-5 signaling pathway

DHX58 DDX60

6.30e-0411712GO:0039530
GeneOntologyBiologicalProcesspositive regulation of RIG-I signaling pathway

DHX58 DDX60

6.30e-0411712GO:1900246
GeneOntologyBiologicalProcessregulation of protein localization to cell surface

ABCA2 ABCA12 ABCA7

7.23e-0451713GO:2000008
GeneOntologyBiologicalProcessregulation of lipid localization

ABCA2 ABCA3 ABCA12 ABCA13 ABCA7

8.75e-04215715GO:1905952
GeneOntologyBiologicalProcessregulation of intracellular lipid transport

ABCA2 ABCA12

8.89e-0413712GO:0032377
GeneOntologyBiologicalProcesspositive regulation of lipid localization

ABCA3 ABCA12 ABCA13 ABCA7

1.03e-03129714GO:1905954
GeneOntologyBiologicalProcessmeiotic telomere clustering

TERB1 MEI1

1.04e-0314712GO:0045141
GeneOntologyBiologicalProcesschromosome localization to nuclear envelope involved in homologous chromosome segregation

TERB1 MEI1

1.04e-0314712GO:0090220
GeneOntologyBiologicalProcessregulation of GTPase activity

KALRN RASGRP3 PKP4 PREX2 SLC27A4 TBC1D20

1.04e-03335716GO:0043087
GeneOntologyCellularComponentlaminin-3 complex

LAMA1 LAMA3

3.21e-053692GO:0005608
GeneOntologyCellularComponentlamellar body membrane

ABCA3 ABCA12

6.42e-054692GO:0097232
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMA3

4.75e-0410692GO:0043256
DomainABC_A

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

2.02e-1212706IPR026082
DomainABC_tran

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

2.41e-0848706PF00005
DomainABC_TRANSPORTER_2

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

2.41e-0848706PS50893
DomainABC_TRANSPORTER_1

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

2.74e-0849706PS00211
DomainABC_transporter-like

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

3.11e-0850706IPR003439
DomainABC_transporter_CS

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

4.89e-0742705IPR017871
DomainARM-type_fold

VAC14 HIP1 PKP4 TERB1 NBEA MEI1 HECTD1 VIRMA MAP3K1 ITPR1

5.13e-073397010IPR016024
DomainAAA+_ATPase

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 DNAH9 ABCA7

1.12e-06144707IPR003593
DomainAAA

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 DNAH9 ABCA7

1.12e-06144707SM00382
DomainARM-like

VAC14 PKP4 TERB1 RIPOR3 NBEA MEI1 HECTD1

6.73e-05270707IPR011989
DomainLaminin_aI

LAMA1 LAMA3

1.37e-045702IPR009254
DomainLaminin_I

LAMA1 LAMA3

1.37e-045702PF06008
DomainLaminin_II

LAMA1 LAMA3

1.37e-045702PF06009
DomainLaminin_domII

LAMA1 LAMA3

1.37e-045702IPR010307
DomainWxxW_domain

CILP MUC5AC

2.06e-046702IPR025155
DomainMucin2_WxxW

CILP MUC5AC

2.06e-046702PF13330
DomainLAMININ_IVA

LAMA1 LAMA3

3.82e-048702PS51115
DomainLaminin_B

LAMA1 LAMA3

3.82e-048702PF00052
DomainLamB

LAMA1 LAMA3

3.82e-048702SM00281
DomainLaminin_IV

LAMA1 LAMA3

3.82e-048702IPR000034
Domain-

ABCA2 ABCA3 ABCA4 DHX58 ABCA12 ABCA13 DDX60 CARD11 DNAH9 ABCA7

4.41e-0474670103.40.50.300
DomainP-loop_NTPase

ABCA2 ABCA3 ABCA4 DHX58 ABCA12 ABCA13 DDX60 CARD11 DNAH9 ABCA7

1.18e-038487010IPR027417
Domain-

VAC14 PKP4 TERB1 RIPOR3 HECTD1

1.47e-032227051.25.10.10
DomainLaminin_N

LAMA1 LAMA3

1.61e-0316702IPR008211
DomainLAMININ_NTER

LAMA1 LAMA3

1.61e-0316702PS51117
DomainLaminin_N

LAMA1 LAMA3

1.61e-0316702PF00055
DomainLamNT

LAMA1 LAMA3

1.61e-0316702SM00136
DomainCARD

CARD6 CARD11

4.91e-0328702PF00619
Domain-

LAMA1 LAMA3 NBEA

5.46e-03957032.60.120.200
DomainEGF_LAM_2

LAMA1 LAMA3

5.63e-0330702PS50027
DomainEGF_LAM_1

LAMA1 LAMA3

5.63e-0330702PS01248
DomainCARD

CARD6 CARD11

6.00e-0331702IPR001315
PathwayKEGG_ABC_TRANSPORTERS

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

5.54e-0944466M11911
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA3 ABCA12 ABCA7

2.29e-0717464MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA3 ABCA12 ABCA7

2.94e-0718464M524
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

1.68e-0599465MM14986
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA2 ABCA3 ABCA4 ABCA12 ABCA7

2.04e-05103465M758
PathwayKEGG_MEDICUS_REFERENCE_RORA_MEDIATED_TRANSCRIPTION

RORA ITPR1

1.04e-045462M49011
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION

RORA ITPR1

1.55e-046462M47665
PathwayPID_INTEGRIN4_PATHWAY

LAMA1 LAMA3

5.62e-0411462M158
Pubmed

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

ABCA2 ABCA3 ABCA12 ABCA7

1.24e-09873424293640
Pubmed

Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment.

LAMA1 LAMA3

4.35e-0627328601594
Pubmed

Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.

ABCA4 ABCA7

1.30e-05373224097981
Pubmed

Regional variation in expression of calbindin and inositol 1,4,5-trisphosphate receptor type 1 mRNAs in the cerebellum of the staggerer mutant mouse.

RORA ITPR1

1.30e-0537328758947
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

VAC14 ABCA2 CD82 ABCA3 OBSL1 ABCA7 PCDH9 MAP3K1 TBC1D20

1.53e-0569773928298427
Pubmed

Dystroglycan protein distribution coincides with basement membranes and muscle differentiation during mouse embryogenesis.

LAMA1 LAMA3

2.60e-05473217676646
Pubmed

mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2.

ABCA2 ABCA3

2.60e-05473224145140
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA1 LAMA3

4.33e-05573211969289
Pubmed

PKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA1.

CARD11 MUC5AC

4.33e-05573222303480
Pubmed

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

ABCA3 ABCA7

4.33e-05573217142808
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA1 LAMA3

4.33e-0557329415429
Pubmed

ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.

ABCA3 ABCA12

4.33e-05573228468577
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA1 LAMA3

4.33e-05573211829758
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA1 LAMA3

4.33e-0557329389447
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA1 LAMA3

6.48e-0567329597096
Pubmed

Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.

ABCA4 ABCA7

6.48e-05673212111378
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMA1 LAMA3

6.48e-0567329506922
Pubmed

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

DHX58 DDX60

9.06e-05773221791617
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

VAC14 ABCA13 PPFIBP2 CARD11 CPLANE1 DNAH9

1.14e-0436173626167880
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA1 LAMA3

1.21e-0487329489770
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA1 LAMA3

1.21e-0487329852162
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA1 LAMA3

1.21e-0487328872465
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA1 LAMA3

1.93e-04107329034910
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA1 LAMA3

2.36e-041173212051813
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA1 LAMA3

2.36e-041173221524702
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA1 LAMA3

2.83e-041273216750824
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA1 LAMA3

2.83e-04127329396756
Pubmed

Autosomal Recessive Congenital Ichthyosis

ABCA12 SLC27A4

3.34e-041373220301593
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA1 LAMA3

3.34e-041373221900571
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA1 LAMA3

3.89e-04147329151674
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA1 LAMA3

4.48e-041573215895400
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA1 LAMA3

4.48e-04157329264260
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA1 LAMA3

5.12e-041673217601529
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

LAMA1 LAMA3

5.12e-041673230579834
Pubmed

Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.

LAMA1 LAMA3

5.12e-041673216880404
Pubmed

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

CD82 MAP3K1

6.51e-041873215829968
Pubmed

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

HIP1 RASGRP3

6.51e-041873219838193
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA1 LAMA3

6.51e-041873211311202
Pubmed

RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.

RORA ITPR1

6.51e-041873214687547
Pubmed

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines.

GRIPAP1 HIP1 MAP3K1

6.98e-048273325260751
Pubmed

PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.

ABCA12 SLC27A4

7.26e-041973228369476
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCA2 ABCA3 ABCA4 ABCA7

7.42e-0419373419343046
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA1 LAMA3

8.06e-042073222911573
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

ABCA2 ABCA3

8.89e-042173223137377
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA4 ABCA12

9.77e-04227328894702
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

ABCA13 DDX60 LAMA1 CARD11

9.80e-0420873433230847
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCA3 ABCA7

1.07e-032373210708515
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

C19orf81 TRIM66 MMS22L ABCA4 RNF125 RDH16 VIRMA ABTB2 MAP3K1

1.14e-03124273930973865
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA1 LAMA3

1.37e-032673224742657
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA1 LAMA3

1.37e-032673234189436
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

ABCA4 PKP4

1.47e-032773218649358
Pubmed

Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling.

RORA ITPR1

1.47e-032773218480159
Pubmed

The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.

RORA ITPR1

1.59e-032873224491816
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA1 LAMA3

1.70e-032973222613833
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

TSHZ3 RORA

2.07e-033273216516881
Pubmed

The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.

ABCA3 MUC5AC

2.07e-033273228546511
Pubmed

Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.

RDH16 CYP17A1

2.07e-033273217270348
Pubmed

Genome-wide association study of lung function decline in adults with and without asthma.

RORA PCDH9

2.07e-033273222424883
Cytoband16q22.1

VAC14 CARMIL2 FBXL8 TERB1

2.99e-0511073416q22.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

VAC14 CARMIL2 FBXL8 TERB1

2.15e-04183734chr16q22
Cytoband2q24.1

PKP4 CCDC148

8.53e-04277322q24.1
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA3 ABCA4 ABCA12 ABCA13 ABCA7

1.10e-1214516805
GeneFamilyLaminin subunits

LAMA1 LAMA3

5.06e-0412512626
GeneFamilyF-box and leucine rich repeat proteins

FBXL8 FBXL4

1.58e-0321512558
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

CARD6 CARD11

3.23e-0330512959
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

KALRN RORA NBEA ANKRD12 PCDH9 ITPR1

1.02e-05177736M39245
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ABCA4 KALRN ABCA12 ABCA13 LAMA1 DNAH9

2.21e-081847372cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ABCA4 KALRN ABCA12 ABCA13 LAMA1 DNAH9

2.21e-08184737ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ABCA4 KALRN ABCA12 ABCA13 LAMA1 DNAH9

2.21e-081847372b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 INMT LAMA1 RIPOR3 PPEF2

4.31e-0792735d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCA4 INMT LAMA1 RIPOR3 PPEF2

4.31e-0792735926e02725a03d8473eda25d4aef63e34a6566224
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 LAMA1 RIPOR3 MAP3K1 CCDC148

5.31e-071817369d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2 MAP3K1

5.48e-07182736a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2 MAP3K1

5.48e-07182736831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

5.66e-0718373631ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

6.03e-07185736898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 PKP4 LAMA1 RIPOR3 CCDC148

6.23e-07186736f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

6.43e-07187736b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 PKP4 LAMA1 RIPOR3 CCDC148

6.43e-07187736c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 FBXL4 ITPR1 CCDC148

6.43e-071877367ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 PKP4 LAMA1 RIPOR3 CCDC148

6.63e-07188736af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

6.84e-07189736f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 RORA PCDH9 CCDC148

6.84e-07189736830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

7.05e-07190736b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

7.05e-071907363dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 ITPR1 CCDC148

7.50e-07192736562df5e87038c500dd3a003fe5374cb31946b145
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NBEA CPLANE1 MUC5AC DNAH9 CFAP46

8.97e-07198736d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ATP13A4 ZNF469 ZNF561-AS1 LRRC17 FBXL4

6.02e-06157735a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 CCDC148

6.60e-0616073503b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NBEA DNAH9 CFAP46 CCDC148

8.61e-0616973514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 RIPOR3 PREX2 MAP3K1

8.86e-061707355d5f208682be21ed58320f5fc083a7898f8712da
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

KALRN RASGRP3 PKP4 SH3RF3 PREX2

9.38e-06172735c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NBEA MUC5AC DNAH9 CFAP46

1.05e-05176735dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 CCDC148

1.11e-051787354df6218b20c2f076c22346d23260964cc0d73e65
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 PREX2 MAP3K1

1.23e-051827358a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 LAMA1 RIPOR3 MAP3K1

1.23e-05182735eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 CCDC148

1.23e-05182735041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 PREX2 MAP3K1

1.23e-05182735e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 ITPR1 CCDC148

1.30e-05184735e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2

1.33e-05185735efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2

1.33e-05185735fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 CCDC148

1.37e-051867351850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 LAMA1 PCDH9 CCDC148

1.37e-051867354dafc215c42e7949f932a3627359c107943b5d6b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2

1.40e-05187735daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ABCA13 LAMA1 RIPOR3 MAP3K1

1.40e-05187735c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 DDX60 PREX2

1.40e-051877355b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 ITPR1 CCDC148

1.44e-051887352ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

KALRN INMT PKP4 SH3RF3 PREX2

1.44e-05188735d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 PREX2 PRODH

1.44e-05188735505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 FBXL4 CCDC148

1.44e-051887353cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 FBXL4 CCDC148

1.48e-05189735e059be2965cca70ff5576df055d0af1775b76e00
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 PREX2 PRODH

1.48e-05189735784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 PREX2 PRODH

1.48e-0518973537ecbd73408d462b47d7e5611f203143e08a2689
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KALRN INMT PKP4 SH3RF3 PREX2

1.52e-051907351caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PKP4 PCDH9 MAP3K1 CCDC148

1.52e-051907353fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP13A4 HIP1 CD82 ABTB2 PREX2

1.52e-0519073507f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 ITPR1 CCDC148

1.52e-05190735cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 LAMA1 OBSL1 PCDH9 CCDC148

1.56e-05191735f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 PKP4 PCDH9 ITPR1 CCDC148

1.56e-05191735963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KALRN RORA PCDH9 PREX2 LRRC17

1.56e-05191735fa380a8752de158974b2ae5e741573439719cc0d
ToppCellhealthy_donor-Lymphocytic-B_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

CD82 RASGRP3 PCDH9 MAP3K1 ITPR1

1.59e-051927357d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCellhealthy_donor-Lymphocytic-B_cell-|healthy_donor / Disease condition, Lineage, Cell class and subclass

CD82 RASGRP3 PCDH9 MAP3K1 ITPR1

1.59e-05192735975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCA4 INMT LAMA1 RIPOR3

1.60e-0592734bbaf5a131f860198840e34843b7c841bcc98d9c4
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCA4 INMT LAMA1 RIPOR3

1.60e-0592734e6aa2b8ca9235a7291ee41d976b886fec185835d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF125 KALRN PKP4 SH3RF3 PREX2

1.63e-051937357261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TSHZ3 KALRN RORA PREX2 LRRC17

1.68e-051947358c37bedb23285735ff3828db3889897fada8c95d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

ATP13A4 HIP1 ZNF507 LAMA3 PCDH9

1.68e-0519473588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ATP13A4 HIP1 ZNF507 LAMA3 PCDH9

1.68e-05194735a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KALRN RORA PCDH9 PREX2 LRRC17

1.68e-05194735a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NBEA MUC5AC DNAH9 CFAP46

1.72e-051957359651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

ATP13A4 HIP1 CD82 PREX2 PRODH

1.94e-05200735e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ATP13A4 CD82 PREX2 PRODH LRRC17

1.94e-052007357c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.50e-0510373439d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.50e-0510373401a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.59e-0510473411d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.59e-05104734424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.59e-051047349b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.90e-0510773413af691c8533418d2800a8eca61155896b559948
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

2.90e-05107734a5a34bb9706527799ddb494d4f1bfc634c29e8a9
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CILP INMT LAMA1 RIPOR3

6.59e-05132734893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ABCA12 LAMA1 DNAH9

8.51e-051417344aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABCA3 LRRC31 CYP17A1 OBSL1

8.51e-05141734f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ABCA12 LAMA1 DNAH9

8.51e-05141734e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABCA3 LRRC31 CYP17A1 OBSL1

8.51e-05141734bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

TUBGCP6 CDKN3 ABCA2 SLC27A4

9.73e-051467347fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX58 BTBD7 ABTB2 SLC27A4

1.03e-04148734b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX58 BTBD7 ABTB2 SLC27A4

1.03e-04148734ba277c898678dd36f8dc1d681301c71901b89055
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 DDX60 RASGRP3 PCDH9

1.08e-041507344bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATP13A4 ABCA4 ABCA13 MAP3K1

1.11e-0415173416fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

ABCA13 DNAH9 CFAP46 CCDC148

1.11e-041517348216462e723fec2797387929dde095370947e10a
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 ABCA3 LAMA3 PCDH9

1.17e-04153734e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 LAMA1 OBSL1 PCDH9

1.17e-041537340307f10e772021ae68a42690634df458672a6df9
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ATP13A4 ZNF469 ZNF561-AS1 LRRC17

1.17e-0415373444572f87d403e314050ab935d2cd676c33d9c287
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ABCA13 DNAH9 CFAP46 CCDC148

1.26e-0415673410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ATP13A4 ABCA3 OBSL1 PCDH9

1.29e-0415773431d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 ZNF469 ZNF561-AS1 LRRC17

1.32e-0415873441cf950983f47a9e55d56041b301006b42853b37
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDH16 ABCA12 LAMA1 DNAH9

1.39e-04160734c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDH16 ABCA12 LAMA1 DNAH9

1.39e-0416073425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

RNF125 RORA ANKRD12 ITPR1

1.45e-04162734b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 HECTD1 PCDH9 CCDC148

1.45e-04162734373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP13A4 PKP4 PCDH9 FBXL4

1.49e-04163734cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDKN3 ZNF469 ABCA13 ZNF507

1.52e-041647344ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF125 RDH16 CYP17A1 PRODH

1.52e-0416473490afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF507 LAMA3 PREX2 PRODH

1.60e-04166734f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF469 CARD11 SH3RF3 ABCA7

1.60e-04166734c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMS22L CARMIL2 CARD6 MEI1

1.67e-041687346c758eb120faf06ff72d157b495e399191c79ec9
Diseaserespiratory system disease

RDH16 RORA CARD11 MUC5AC

4.44e-04145724EFO_0000684
Diseaseneuroticism measurement, cognitive function measurement

MMS22L VAC14 KALRN ZNF507 CPNE1 RORA PCDH9

4.62e-04566727EFO_0007660, EFO_0008354
Diseaseautism spectrum disorder (implicated_via_orthology)

TSHZ3 ABCA3 PKP4 NBEA

5.30e-04152724DOID:0060041 (implicated_via_orthology)
DiseaseColorectal Neoplasms

ABCA3 ABCA4 ABCA12 ABCA13 LAMA1

5.89e-04277725C0009404
Diseaseacute graft vs. host disease, donor genotype effect measurement

KALRN RORA

6.04e-0415722EFO_0004599, EFO_0007892
Diseaseneutrophil collagenase measurement

ABCA13 CPNE1

6.89e-0416722EFO_0008248
DiseaseColorectal Carcinoma

ABCA3 ABCA4 KALRN ABCA12 ABCA13 LAMA1 PREX2

1.62e-03702727C0009402
Diseaseneuroticism measurement

MMS22L CYP17A1 PKP4 ZNF507 RORA CARD11 PCDH9 ITPR1

1.65e-03909728EFO_0007660
DiseaseInhalant adrenergic use measurement

RORA CARD11 MUC5AC

1.69e-0396723EFO_0009941

Protein segments in the cluster

PeptideGeneStartEntry
SDETMAAICCALHEV

PKP4

931

Q99569
QHICSDFEVMDELSC

nan

61

Q0VG73
MCRCSLVLLSVDHEV

C22orf39

1

Q6P5X5
AVLTLTEACATHEME

CCDC148

336

Q8NFR7
TSHSMEECEALCTRL

ABCA4

2126

P78363
LCAAMASCHSLILLD

ATP13A4

526

Q4VNC1
SHSMEECEALCTRLA

ABCA12

2446

Q86UK0
CLSCVDMKLSLEVSE

CARMIL2

221

Q6F5E8
LTLKCMEISSACLSD

CFAP46

301

Q8IYW2
SHSMEECEALCTRLA

ABCA3

1571

Q99758
LTSHSMEECEALCTR

ABCA13

4911

Q86UQ4
VLTHLSRCDSDLCEM

ANKRD12

1641

Q6UB98
REHLDMCQALSCHTD

ADAMTS13

326

Q76LX8
TSHSMEECEALCSRL

ABCA7

1981

Q8IZY2
MVLSICLCRHVHSED

CD82

246

P27701
KTDSLAHCISEDCRM

OARD1

26

Q9Y530
FVHAITSECVMLACE

OBSL1

816

O75147
CLCMETLPEEDFTHL

C19orf81

81

C9J6K1
ISAELMEEALCTACC

CDIPTOSP

41

P0DO92
DCDSCVMTLLNDLAT

LAMA3

1821

Q16787
LTLLAMECACCSLDA

INMT

161

O95050
DKEHTCETLLMCIVT

ITPR1

2531

Q14643
EEHCETLLCDLISLS

MMS22L

256

Q6ZRQ5
HCTCEIETLISMLQI

LRRC17

166

Q8N6Y2
ECEDSQLVSHLMSCK

DDX60

1566

Q8IY21
TEMCTQECLVLGHSD

PCDH9

1126

Q9HC56
DLHQCSLTADDVMSL

LRRC31

316

Q6UY01
LCISHSRSSVEMDCF

KALRN

1706

O60229
QSLISREECLCHSMI

TUBGCP6

161

Q96RT7
CHMTDLDVVCSSLEL

MUC5AC

5176

P98088
CSLEDLRSESVDKCM

PPFIBP2

386

Q8ND30
LLCSMEDGSVTDLCI

MEI1

101

Q5TIA1
LSRLECSDVIMDHCS

ZNF561-AS1

36

K7EIQ3
MIHFCSEALLKEVCD

HECTD1

551

Q9ULT8
IHTCINLDVRESCFM

IL36B

106

Q9NZH7
LDVLCATMLCSDSSL

CARD6

376

Q9BX69
VEFDSCMIEHCLSAV

CPLANE1

1311

Q9H799
HFLNETCLEVISEMC

FBXL4

386

Q9UKA2
HDTKISCECELEGML

FBXL8

46

Q96CD0
ICQEISTLCDMLATH

CYP17A1

146

P05093
CHDLLICTAELLQMA

DHX58

96

Q96C10
TSHSMEECEALCTRL

ABCA2

2241

Q9BZC7
CMYTDVVDLSVLHCS

BTBD7

331

Q9P203
QMVCHLLECLLTTED

DNAH9

2346

Q9NYC9
HLEVSSASMAEDLCR

GRIPAP1

731

Q4V328
IASCCEIMEELTTCL

CDKN3

116

Q16667
CTMSLKCDDVVHVRD

CARD11

791

Q9BXL7
MAHCVTLVQLSISCD

CPNE1

1

Q99829
SHMNIDITDDCICDL

PPEF2

686

O14830
CLLGMLDEESLTVCE

MAP3K1

446

Q13233
HCQTTDDLIQLTAMC

VAC14

266

Q08AM6
LSLVTNCMEHALIAC

RDH16

261

O75452
TLDELLCTCIEMFDD

RASGRP3

11

Q8IV61
HILMETDCVSCDDEC

LAMA1

1546

P25391
ESITCMTELLEHCDV

NBEA

116

Q8NFP9
MTELLEHCDVTCQAE

NBEA

121

Q8NFP9
EELMVCSHEIAASTA

HIP1

901

O00291
AKCDSHMETFLRCIE

PRODH

206

O43272
AILVDDMADTCVTIC

PRPS1L1

216

P21108
QRHCEILCSQTLSME

ABTB2

936

Q8N961
ICLAEMVSLCSEASE

CILP

176

O75339
LRHLQCSLDDTDMSC

TRIM77

306

I1YAP6
AECDTLVCLSEMRAH

RNF125

101

Q96EQ8
EHTSAESLMECILES

RIPOR3

556

Q96MK2
SEMASAICEVHASLD

SLC27A4

181

Q6P1M0
CSMHLTEDEIALFSA

RORA

411

P35398
MDESSLLDLLECSVC

SH3RF3

46

Q8TEJ3
EMCVCQIDDLLSSIT

PREX2

1041

Q70Z35
LKCMECGSSHDTLQE

TSHZ3

386

Q63HK5
CSVALMSHLSEDELE

ZNF469

1521

Q96JG9
NEVILMCSECHITSR

ZNF507

151

Q8TCN5
MCSECHITSRSQEEL

ZNF507

156

Q8TCN5
LDCDCDMASVHHLLS

TBC1D20

266

Q96BZ9
DMLTCHSCLVVEHKE

TRIM66

81

O15016
ELMTSICDCLLATLA

VIRMA

1321

Q69YN4
SIMLTLGHCTEDCEE

TERB1

316

Q8NA31