Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	ruffle	LIMA1 ABL1 MTSS1 ABCA7 PTPRJ EPHA2 CSPG4 FGD5 PSD4	4.94e-05	206	170	9	GO:0001726
GeneOntologyCellularComponent	histone deacetylase complex	ARID4B ZNF217 NCOR1 BRD8 SETD5 RERE	6.81e-05	85	170	6	GO:0000118
GeneOntologyCellularComponent	nuclear chromosome	SYCP2L ARID4B POLE2 CAMSAP3 E2F6 BRD8 SETD5 IK RAD9A	2.42e-04	254	170	9	GO:0000228
GeneOntologyCellularComponent	IRE1-TRAF2-ASK1 complex	ERN1 MAP3K5	3.90e-04	4	170	2	GO:1990604
Domain	VCX_VCY	VCX2 VCX3A VCX3B VCX	3.14e-08	5	168	4	PF15231
Domain	VCX/VCY1	VCX2 VCX3A VCX3B VCX	3.14e-08	5	168	4	IPR026653
Domain	SET	SETD1B PRDM4 KMT2D KMT5B SETD5	5.64e-05	46	168	5	SM00317
Domain	SET_dom	SETD1B PRDM4 KMT2D KMT5B SETD5	8.47e-05	50	168	5	IPR001214
Domain	SET	SETD1B PRDM4 KMT2D KMT5B SETD5	8.47e-05	50	168	5	PS50280
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABL1 SETD1B MORN1 ESYT1 GBX2 WNK1 NPHP4 BIRC6 ABCA7 KIFC2 MAP3K5 TYK2 NCOR1 KMT2D SCAP PTPRF SETD5 PTPRS CSPG4 NAV1 SNX15 FGFR1 ATG9A SLC45A1 RAD9A	2.88e-10	1105	173	25	35748872
Pubmed	A member of a gene family on Xp22.3, VCX-A, is deleted in patients with X-linked nonspecific mental retardation.	VCX2 VCX3A VCX3B VCX	5.91e-10	4	173	4	10903929
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 ATXN7L2 ARID4B MAP1A BIRC2 CHD9 RAB11FIP1 RREB1 ABCA7 TYK2 PASK ZBTB7A BRD8 IGFBP1 HMCN2 PRPF40B KMT5B SETD5 WDR6 ANKRD2 PIP4K2A RERE SRRM2 ZNF646	1.84e-09	1116	173	24	31753913
Pubmed	A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins.	VCX2 VCX3A VCY VCX	2.95e-09	5	173	4	10607842
Pubmed	Analysis of the VCX3A, VCX2 and VCX3B genes shows that VCX3A gene deletion is not sufficient to result in mental retardation in X-linked ichthyosis.	VCX2 VCX3A VCX3B	1.21e-07	3	173	3	18076704
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 CAMSAP3 E2F6 ZNF217 RREB1 BIRC6 NCOR1 KMT2D GTF3C1 WDR6 NAV1 RERE NPAT	2.01e-07	418	173	13	34709266
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZNF536 HECW1 CHD9 WNK1 SRRM2 PDZD2 ZNF646	9.45e-07	104	173	7	9205841
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF536 SETD1B SORBS1 GPATCH8 SETD5 STARD9 NAV1 OGFOD1 RERE SRRM2 DOP1B PDZD2	1.05e-06	407	173	12	12693553
Pubmed	Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.	PTPRF PTPRS BSN	1.20e-06	5	173	3	22357843
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ARHGAP32 LIMA1 AMER1 ABL1 ESYT1 CAMSAP3 SORBS1 RAB11FIP1 WNK1 SH3PXD2A STARD9 MAP3K9 NAV1 SRRM2 YTHDF2 WNK4 DOP1B	1.60e-06	861	173	17	36931259
Pubmed	A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family.	VCX3B VCY VCX	2.39e-06	6	173	3	17342728
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB15 PCDHB14 PCDHB12 PCDHB9	2.69e-06	20	173	4	11322959
Pubmed	Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.	BIRC2 PTPRF PTPRS	4.17e-06	7	173	3	29073098
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	PDXDC1 BIRC2 GPATCH8 TRIM3 GTF3C1 PTPRF PTPRS WDR6 EPHA2 IK	4.21e-06	313	173	10	38270169
Pubmed	Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.	MKRN3 PCDHB15 NDN	6.65e-06	8	173	3	23819640
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A4P ANKRD20A1	6.65e-06	8	173	3	12634303
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	ABL1 TYK2 EPHA2 FGFR1	6.89e-06	25	173	4	15254900
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIMA1 ARID4B TBC1D2 CAMSAP3 ZNF217 GPATCH8 RREB1 PASK NCOR1 ZBTB7A KMT2D BRD8 GTF3C1 RERE SRRM2	8.41e-06	774	173	15	15302935
Pubmed	Human transcription factor protein interaction networks.	ARHGAP32 ZNF536 LIMA1 ATXN7L2 ARID4B PHF23 E2F6 ZNF217 GPATCH8 GMEB2 RREB1 NCOR1 ZBTB7A KMT2D BRD8 GTF3C1 RERE SRRM2 IMMT YTHDF2 NPAT	9.53e-06	1429	173	21	35140242
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB15 PCDHB14 PCDHB12 PCDHB9 GBX2	1.06e-05	58	173	5	30377227
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF536 ARID4B E2F6 ZNF217 RREB1 NCOR1 KMT2D WDR6 RERE IMMT	1.14e-05	351	173	10	38297188
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	LIMA1 ANK2 PPP1R12B CAMSAP3 SORBS1	2.16e-05	67	173	5	29254152
Pubmed	AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix.	AIRE UBAC1	2.46e-05	2	173	2	16310047
Pubmed	Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.	ABL1 ERN1	2.46e-05	2	173	2	28380378
Pubmed	Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures.	ABL1 PAK2	2.46e-05	2	173	2	16867995
Pubmed	The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1).	HIC1 EPHA2	2.46e-05	2	173	2	22184117
Pubmed	Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK.	ABL1 PAK2	2.46e-05	2	173	2	11121037
Pubmed	Hypertension associated polymorphisms in WNK1/WNK4 are not associated with hydrochlorothiazide response.	WNK1 WNK4	2.46e-05	2	173	2	21704025
Pubmed	Modulation of neuritogenesis by a protein implicated in X-linked mental retardation.	VCX3A VCX3B	2.46e-05	2	173	2	19812318
Pubmed	Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.	WNK1 WNK4	2.46e-05	2	173	2	22294159
Pubmed	A novel protein encoded by circASK1 ameliorates gefitinib resistance in lung adenocarcinoma by competitively activating ASK1-dependent apoptosis.	MAP3K5 YTHDF2	2.46e-05	2	173	2	34389432
Pubmed	Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.	WNK1 WNK4	2.46e-05	2	173	2	16899520
Pubmed	WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.	WNK1 WNK4	2.46e-05	2	173	2	25113964
Pubmed	Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.	WNK1 WNK4	2.46e-05	2	173	2	29846116
Pubmed	Expression and localization of VCX/Y proteins and their possible involvement in regulation of ribosome assembly during spermatogenesis.	VCX3B VCX	2.46e-05	2	173	2	12862317
Pubmed	Foxa2 may modulate hepatic apoptosis through the cIAP1 pathway.	BIRC2 FOXA2	2.46e-05	2	173	2	23275033
Pubmed	WNK kinases regulate thiazide-sensitive Na-Cl cotransport.	WNK1 WNK4	2.46e-05	2	173	2	12671053
Pubmed	The metabolic sensor PASK is a histone 3 kinase that also regulates H3K4 methylation by associating with H3K4 MLL2 methyltransferase complex.	PASK KMT2D	2.46e-05	2	173	2	31529049
Pubmed	ProSAAS processing in mouse brain and pituitary.	CPE PCSK1N	2.46e-05	2	173	2	11094058
Pubmed	Inhibition of IRE1 modifies the hypoxic regulation of GADD family gene expressions in U87 glioma cells.	ERN1 PPP1R15A	2.46e-05	2	173	2	29227599
Pubmed	A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.	VCY VCX	2.46e-05	2	173	2	24970476
Pubmed	WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron.	WNK1 WNK4	2.46e-05	2	173	2	16820787
Pubmed	Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP.	RERE SLC45A1	2.46e-05	2	173	2	10729226
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHB15 PCDHB14 PCDHB12 PCDHB9 FAT2	3.07e-05	72	173	5	10380929
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	DDX59 SETD1B ARID4B PHF23 ACSM1 ZNF217 GPATCH8 PRDM4 WNK1 BIRC6 BRD8 SCAP UPF2 KMT5B PAK2 RASEF ATG9A RERE YTHDF2	3.71e-05	1327	173	19	32694731
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MAP1A TBC1D2 ZNF217 NPHP4 NCOR1 KMT2D NAV1	4.02e-05	184	173	7	32908313
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB15 PCDHB14 PCDHB12 PCDHB9 FAT2	4.25e-05	77	173	5	10835267
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	HIC1 ABL1 SETD1B GRWD1 MTSS1 KIFC2 ZFP36 MAP3K5	4.72e-05	257	173	8	30945288
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	CNKSR1 CAMSAP3 TACC2 RAB11FIP1 WNK1 NCOR1 BRD8 GTF3C1 SSH3 PAK2 SRRM2	4.78e-05	503	173	11	16964243
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB15 PCDHB14 PCDHB12 PCDHB9 FAT2	5.11e-05	80	173	5	10716726
Pubmed	Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors.	DBP FOXA2 IGFBP1	5.27e-05	15	173	3	12163409
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	AMER1 POLE2 TBC1D2 BIRC2 PNKD BIRC6 PARP10 KMT2D GTF3C1 WDR6 UBAC1 IMMT	5.44e-05	604	173	12	38803224
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAGEA8 ARHGAP32 MAP1A PHF23 APC2 PRDM4 WNK1 NCOR1 BSN WNK4	6.38e-05	430	173	10	35044719
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	AMER1 SETD1B TBC1D2 BIRC6 FREM2 RERE CPLANE1 SRRM2 YTHDF2 DOP1B	6.51e-05	431	173	10	33660365
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRF PTPRS	7.36e-05	3	173	2	31985401
Pubmed	c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.	ABL1 RAD9A	7.36e-05	3	173	2	11971963
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRF PTPRS	7.36e-05	3	173	2	20139422
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRF PTPRS	7.36e-05	3	173	2	33656439
Pubmed	Cbl-associated protein is tyrosine phosphorylated by c-Abl and c-Src kinases.	ABL1 SORBS1	7.36e-05	3	173	2	19891780
Pubmed	Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.	WNK1 WNK4	7.36e-05	3	173	2	24821705
Pubmed	Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.	WNK1 WNK4	7.36e-05	3	173	2	29667910
Pubmed	Clinical investigation of lipopolysaccharide in the persistence of metabolic syndrome (MS) through the activation of GRP78-IRE1α-ASK1 signaling pathway.	ERN1 MAP3K5	7.36e-05	3	173	2	34850317
Pubmed	IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to CXC195-induced apoptosis in human bladder carcinoma T24 cells.	ERN1 MAP3K5	7.36e-05	3	173	2	25797626
Pubmed	Disruption of the mouse necdin gene results in early post-natal lethality.	MKRN3 NDN	7.36e-05	3	173	2	10508517
Pubmed	Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs.	MKRN3 NDN	7.36e-05	3	173	2	30102380
Pubmed	Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.	WNK1 WNK4	7.36e-05	3	173	2	16788137
Pubmed	Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.	ZNF750 KMT2D	7.36e-05	3	173	2	27749841
Pubmed	Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.	MAP3K5 MAP3K9	7.36e-05	3	173	2	22197930
Pubmed	ProSAAS and prohormone convertase 1 are broadly expressed during mouse development.	CPE PCSK1N	7.36e-05	3	173	2	15018810
Pubmed	Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype.	MKRN3 NDN	7.36e-05	3	173	2	10915770
Pubmed	Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF.	PAK2 MUC5AC	7.36e-05	3	173	2	17555715
Pubmed	WNK kinases influence TRPV4 channel function and localization.	WNK1 WNK4	7.36e-05	3	173	2	16403833
Pubmed	Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway.	ERN1 MAP3K5	7.36e-05	3	173	2	28349059
Pubmed	Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.	WNK1 WNK4	7.36e-05	3	173	2	29459793
Pubmed	The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice.	FGFR1 NPAS1	7.36e-05	3	173	2	16172381
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRF PTPRS	7.36e-05	3	173	2	9784606
Pubmed	Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migration.	PTPRF EPHA2	7.36e-05	3	173	2	23358419
Pubmed	Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.	TYK2 RAD9A	7.36e-05	3	173	2	9733772
Pubmed	Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.	ABL1 SORBS1	7.36e-05	3	173	2	11374898
Pubmed	Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.	NCOR1 SETD5	7.36e-05	3	173	2	34857762
Pubmed	Knockout mice with pituitary malformations help identify human cases of hypopituitarism.	KMT5B SETD5 SH3PXD2A NPAT	7.51e-05	45	173	4	38822427
Pubmed	Protein tyrosine phosphatases expression during development of mouse superior colliculus.	PTPRF PTPRJ PTPRS	7.81e-05	17	173	3	19727691
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 LIMA1 ANK2 HECW1 APC2 CAMSAP3 SORBS1 ITIH1 TRIM3 MAP3K5 NCOR1 PTPRS NAV1 PAK2 BSN	1.02e-04	963	173	15	28671696
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	LIMA1 AMER1 ANK2 PPP1R12B CAMSAP3 SLC4A3 NCOR1 RFTN1 GTF3C1 SETD5 SH3PXD2A STARD9 CSPG4 PIP4K2A FGFR1 BSN SEC61A1 KIAA2012 IMMT	1.11e-04	1442	173	19	35575683
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PDXDC1 ARHGAP32 ESYT1 RFTN1 PTPRF PTPRJ PTPRS EPHA2 CSPG4	1.22e-04	377	173	9	38117590
Pubmed	Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.	ABL1 TYK2 EPHA2	1.30e-04	20	173	3	7893599
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 WNK1 BIRC6 HEPH PASK SCAP DOP1B	1.42e-04	225	173	7	12168954
Pubmed	Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.	PTPRF PTPRS	1.47e-04	4	173	2	14967925
Pubmed	CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.	ERN1 PPP1R15A	1.47e-04	4	173	2	15601821
Pubmed	IAPs: more than just inhibitors of apoptosis proteins.	BIRC2 BIRC6	1.47e-04	4	173	2	18414036
Pubmed	Structural insights into the recognition of substrates and activators by the OSR1 kinase.	WNK1 WNK4	1.47e-04	4	173	2	17721439
Pubmed	FBI-1 functions as a novel AR co-repressor in prostate cancer cells.	NCOR1 ZBTB7A	1.47e-04	4	173	2	20812024
Pubmed	ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.	ERN1 MAP3K5	1.47e-04	4	173	2	12050113
Pubmed	The OPCML tumor suppressor functions as a cell surface repressor-adaptor, negatively regulating receptor tyrosine kinases in epithelial ovarian cancer.	EPHA2 FGFR1	1.47e-04	4	173	2	22585860
Pubmed	WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.	WNK1 WNK4	1.47e-04	4	173	2	11571656
Pubmed	Human hypertension caused by mutations in WNK kinases.	WNK1 WNK4	1.47e-04	4	173	2	11498583
Pubmed	Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.	PTPRF PTPRS	1.47e-04	4	173	2	26231120
Pubmed	Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain.	MKRN3 NDN	1.47e-04	4	173	2	12971993
Pubmed	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.	PTPRF PTPRS	1.47e-04	4	173	2	8524829
Pubmed	Pseudohypoaldosteronism Type II	WNK1 WNK4	1.47e-04	4	173	2	22073419
Interaction	TOP3B interactions	LIMA1 ABL1 SETD1B GRWD1 MORN1 ESYT1 GBX2 WNK1 NPHP4 BIRC6 ABCA7 KIFC2 ZFP36 MAP3K5 TYK2 NCOR1 KMT2D SCAP PTPRF UPF2 SETD5 PTPRS CSPG4 NAV1 SNX15 FGFR1 ATG9A SLC45A1 IMMT YTHDF2 RAD9A	1.24e-06	1470	167	31	int:TOP3B
Interaction	FEV interactions	ARID4B E2F6 ZNF217 GPATCH8 GMEB2 RREB1 NCOR1 ZBTB7A KMT2D GTF3C1	7.72e-06	203	167	10	int:FEV
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.10e-05	6	167	3	int:ANKRD20A4P
Interaction	ARRDC3 interactions	PDXDC1 BIRC2 GPATCH8 TRIM3 PTPRF PTPRS WDR6 EPHA2 UBAC1 IK	1.82e-05	224	167	10	int:ARRDC3
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.91e-05	7	167	3	int:ANKRD20A2P
Interaction	TNK2 interactions	LIMA1 ANK2 HECW1 PPP1R12B CAMSAP3 SORBS1 CSPG4 FGFR1 ATG9A	3.71e-05	195	167	9	int:TNK2
Cytoband	5q31	PCDHB15 PCDHB14 PCDHB12 PCDHB9 BRD8	8.09e-05	115	174	5	5q31
GeneFamily	Variable charge X/Y family	VCX2 VCX3A VCX3B VCY VCX	5.21e-11	6	113	5	368
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRF PTPRJ PTPRS	2.91e-04	21	113	3	813
GeneFamily	Clustered protocadherins	PCDHB15 PCDHB14 PCDHB12 PCDHB9	6.89e-04	64	113	4	20
GeneFamily	Ankyrin repeat domain containing	ANK2 PPP1R12B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 ANKRD20A1	8.18e-04	242	113	7	403
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	BIRC2 BIRC6	1.06e-03	8	113	2	419
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1B KMT2D KMT5B	1.24e-03	34	113	3	487
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF536 HIC1 ZKSCAN7 ZNF217 RREB1 PRDM4 ZNF446 ZIC4 ZBTB7A ZNF792 ZBTB3 ZNF646	1.77e-03	718	113	12	28
Coexpression	GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP	ESYT1 ABCA7 IER2 TYK2 KMT2D BLCAP SCAP PTPRJ WDR6 OGFOD1	7.68e-07	196	173	10	M6293
Coexpression	GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_UP	SYCP2L ATXN7L2 APC2 SLC4A3 FREM2 IGFBP1 PTPRS CSPG4 BSN	8.06e-07	152	173	9	M405
Coexpression	GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN	TACC2 GPATCH8 IRAG1 WNK1 BIRC6 MAP3K5 SCAP EPHA2 PIP4K2A SRRM2	8.82e-07	199	173	10	M6964
Coexpression	LIU_PROSTATE_CANCER_DN	ZNF536 ANK2 EFS PPP1R12B FHOD3 SORBS1 IRAG1 HEPH ARL10 SH3PXD2A EPHA2 FGD5 FGFR1	2.58e-05	493	173	13	M19391
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	LIMA1 ABL1 ANK2 CPE PPP1R15A ZFP36 IER2 PTPRS FGFR1 NOVA1	2.92e-05	296	173	10	M41675
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	ABL1 POLE2 BIRC2 CHD9 ZNF217 CERS6 MAP3K5 FAT2 BRD8 NPAT	3.27e-05	300	173	10	M8702
Coexpression	GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_UP	ESYT1 MTSS1 ZKSCAN7 RFTN1 LY9 ZBTB3 PSD4 NPAT	3.32e-05	185	173	8	M5643
Coexpression	GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN	CERS6 BIRC6 MAP3K5 SCAP PIP4K2A PAK2 SRRM2 SEC61A1	5.56e-05	199	173	8	M6987
Coexpression	GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	APC2 WNK1 BIRC6 UPF2 EPHA2 PIP4K2A SRRM2 SEC61A1	5.76e-05	200	173	8	M291
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN	GRWD1 ZNF217 DBP RREB1 ZBTB7A PIANP GTF3C1 RERE	5.76e-05	200	173	8	M3579
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN	CHD9 DBP WNK1 ABCA7 MAP3K5 KMT2D PTPRJ LY9	5.76e-05	200	173	8	M7150
Coexpression	GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN	ERN1 MTSS1 SLC13A3 PPP1R15A ZFP36 MAP3K5 BLCAP PTPRJ	5.76e-05	200	173	8	M5600
Coexpression	BUSSLINGER_DUODENAL_MX_CELLS	CPE PCSK1N FGFR1	7.70e-05	13	173	3	M40036
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	ANK2 CHD9 FHOD3 SLC13A3 PTPRJ RERE SRRM2 PDZD2	1.16e-04	221	173	8	M39222
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	ARPP19 ARID4B BSDC1 SORBS1 GPATCH8 GMEB2 PPP1R15A RAB11FIP1 PRDM4 ZFP36 IGFBP1 UPF2 SETD5 MAP3K9 FGFR1 PDZD2	1.17e-04	822	173	16	M6782
Coexpression	FIGUEROA_AML_METHYLATION_CLUSTER_4_DN	GBX2 PTPRS EPHA2	1.21e-04	15	173	3	M2171
Coexpression	CAIRO_LIVER_DEVELOPMENT_UP	ARPP19 GRWD1 NDN HEPH PTPRS FGFR1 PDZD2	1.21e-04	166	173	7	M17163
Coexpression	CAIRO_LIVER_DEVELOPMENT_UP	ARPP19 GRWD1 NDN HEPH PTPRS FGFR1 PDZD2	1.26e-04	167	173	7	MM1057
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	SYCP2L ANK2 APC2 MTSS1 APLP1 FHOD3 SORBS1 CERS6 SLC4A3 KIFC2 FAT2 PIANP BLCAP SH3PXD2A MAP3K9 NAV1 BSN NOVA1 DOP1B	1.37e-04	1106	173	19	M39071
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 ESYT1 APLP1 CPE NCOR1 PTPRF WDR6 SH3PXD2A PCSK1N SRRM2	4.86e-09	194	173	10	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 APLP1 CPE NCOR1 PTPRF WDR6 SH3PXD2A PCSK1N SRRM2	7.21e-08	194	173	9	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 ANKRD2 PDZD2	6.65e-07	185	173	8	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	HECW1 CAMSAP3 CERS6 KIFC2 ZBTB7A PIANP SLC45A1 BSN	6.93e-07	186	173	8	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 APC2 APLP1 FHOD3 SMIM28 PCSK1N BSN ECE2	7.82e-07	189	173	8	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 SLC4A3 PDZD2	8.13e-07	190	173	8	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE TACC2 NCOR1 PTPRF SH3PXD2A PCSK1N SRRM2	8.80e-07	192	173	8	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE TACC2 NCOR1 PTPRF SH3PXD2A PCSK1N SRRM2	9.52e-07	194	173	8	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW1 MTSS1 TACC2 NDN CSPG4 NAV1 FGFR1 PDZD2	1.15e-06	199	173	8	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW1 MTSS1 TACC2 NDN CSPG4 NAV1 FGFR1 PDZD2	1.15e-06	199	173	8	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 SLC13A3 CERS6 PRDM4 GTF3C1 PTPRJ PCSK1N	1.63e-06	145	173	7	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|World / disease group, cell group and cell class (v2)	MAP1A NDN SORBS1 SLC4A3 PTPRS EPHA2 ZBTB3	4.15e-06	167	173	7	bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 ZKSCAN7 PTPRF PTPRS EPHA2 MUC5AC CCDC40	5.24e-06	173	173	7	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARID4B MTSS1 CHD9 PPP1R15A RAB11FIP1 PRDM4 RERE	5.24e-06	173	173	7	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 ZKSCAN7 PTPRF PTPRS EPHA2 MUC5AC CCDC40	5.24e-06	173	173	7	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PCDHB15 PCDHB12 FHOD3 ZNF750 FREM2 NOVA1 PDZD2	5.44e-06	174	173	7	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PCDHB15 PCDHB12 FHOD3 ZNF750 FREM2 NOVA1 PDZD2	5.44e-06	174	173	7	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PCDHB15 PCDHB12 FHOD3 ZNF750 FREM2 NOVA1 PDZD2	5.44e-06	174	173	7	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PCDHB15 PCDHB12 FHOD3 ZNF750 FREM2 NOVA1 PDZD2	5.44e-06	174	173	7	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDXDC1 ARHGAP32 RAB11FIP1 SH3PXD2A EPHA2 RASEF MUC5AC	6.55e-06	179	173	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 CAMSAP3 TACC2 PTPRF PTPRS EPHA2 FGFR1	6.55e-06	179	173	7	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZNF536 MTSS1 PODXL2 SORBS1 PCSK1N ECE2 NPAS1	7.30e-06	182	173	7	f2a1784ffcba9b27132e0db21e574cbd8a0a6418
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EFS PCDHB14 CPE PIANP CSPG4 FGFR1 WNK4	7.30e-06	182	173	7	ed487f3a774812caa2903a646b60c86edcc1e65e
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ABL1 ANKRD20A2P ANKRD20A3P RFTN1 ANKRD20A4P UPF2 ANKRD20A1	7.84e-06	184	173	7	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	ARID4B CHD9 NDN NCOR1 KMT5B SRRM2 NOVA1	8.13e-06	185	173	7	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NDN PPP1R15A ZFP36 IER2 PCSK1N	8.13e-06	185	173	7	4e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell	IPF-Myeloid-DC_Mature\|World / Disease state, Lineage and Cell class	MTSS1 CERS6 ITIH1 RFTN1 BICDL1 SH3PXD2A NAV1	8.42e-06	186	173	7	d0d3953d9b199e0e792990b8551efb993393fe7e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NDN PPP1R15A ZFP36 IER2 PCSK1N	8.42e-06	186	173	7	16092819e9148dfe64f07c737652b6e533e699f7
ToppCell	IPF-Myeloid-DC_Mature\|IPF / Disease state, Lineage and Cell class	MTSS1 CERS6 ITIH1 RFTN1 BICDL1 SH3PXD2A NAV1	8.72e-06	187	173	7	63e0304a0183b69aebb0d1a4640a506a0d6fb6e9
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 APLP1 CPE PTPRF SH3PXD2A NAV1 PCSK1N	9.02e-06	188	173	7	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	ANK2 APLP1 PODXL2 CPE FOXA2 PCSK1N NOVA1	9.02e-06	188	173	7	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-1\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	PPP1R12B ACSM1 SORBS1 IRAG1 HMCN2 SSH3	9.09e-06	124	173	6	57f3335f751868a768934c757b06a6378148dc9e
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NDN PPP1R15A ZFP36 IER2 PCSK1N	9.34e-06	189	173	7	ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 MAP1A APLP1 CPE IRAG1 PCSK1N NOVA1	9.34e-06	189	173	7	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 PDZD2	9.34e-06	189	173	7	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 MAP1A APLP1 CPE IRAG1 PCSK1N NOVA1	9.34e-06	189	173	7	381058f55908f84375b54601d617389ef43ab855
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 MAP1A APLP1 CPE IRAG1 PCSK1N NOVA1	9.34e-06	189	173	7	302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-duct_epithelial_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPG CNKSR1 EFS CPE CERS6 ZNF750 UPF2	9.67e-06	190	173	7	5b3f773380aef4773b70f0dbd74992d28e6586c6
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NDN PPP1R15A ZFP36 IER2 PCSK1N	9.67e-06	190	173	7	db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 PDZD2	1.00e-05	191	173	7	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 SLC4A3	1.00e-05	191	173	7	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ABL1 ANKRD20A2P ANKRD20A3P RFTN1 ANKRD20A4P UPF2 ANKRD20A1	1.00e-05	191	173	7	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ABL1 ANKRD20A2P ANKRD20A3P RAB11FIP1 ANKRD20A4P UPF2 ANKRD20A1	1.03e-05	192	173	7	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-27\|World / Primary Cells by Cluster	APLP1 PODXL2 CPE NDN PCSK1N RERE NOVA1	1.03e-05	192	173	7	cf989f26c0ebdc0cd12e1e41958f063e4fa3e468
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDXDC1 TBC1D2 FOXA2 PTPRF RASEF WNK4 DOP1B	1.07e-05	193	173	7	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TACC2 CERS6 RAB11FIP1 FAT2 SH3PXD2A EPHA2 RASEF	1.07e-05	193	173	7	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDXDC1 TBC1D2 FOXA2 PTPRF RASEF WNK4 DOP1B	1.07e-05	193	173	7	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 ESYT1 APLP1 CPE PTPRF SH3PXD2A PCSK1N	1.07e-05	193	173	7	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 CERS6 PDZD2	1.11e-05	194	173	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARPP19 MTSS1 CHD9 PPP1R15A RAB11FIP1 UPF2 RERE	1.14e-05	195	173	7	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARPP19 MTSS1 CHD9 PPP1R15A RAB11FIP1 UPF2 RERE	1.14e-05	195	173	7	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	mild_COVID-19-MAIT\|World / disease group, cell group and cell class (v2)	ERN1 PPP1R15A ZFP36 IER2 BICDL1 GTF3C1 PCSK1N	1.14e-05	195	173	7	74f0f709d9b3eed5d7e02a51884f02cc281782f1
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NCOR1 PTPRF PCSK1N RERE SRRM2	1.14e-05	195	173	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NCOR1 PTPRF PCSK1N RERE SRRM2	1.14e-05	195	173	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Heart-HEART-1m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODXL2 CPE NDN DBP PTPRS CSPG4 FGFR1	1.18e-05	196	173	7	1eb14182ef26e6141f510d397b00bf8a12efda3e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC\|World / Primary Cells by Cluster	APLP1 PODXL2 CPE NCOR1 PAK2 PCSK1N RERE	1.22e-05	197	173	7	2c3b0072f8e1e09c77a85c6fc3133d1796932fb2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC-29\|World / Primary Cells by Cluster	APLP1 PODXL2 CPE NCOR1 PAK2 PCSK1N RERE	1.22e-05	197	173	7	c5bc0e7eb85642b270efc2ba92b13a736af22052
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CDC42BPG ANKRD20A2P ANKRD20A3P SLC4A3 ANKRD20A4P CCDC40	1.24e-05	131	173	6	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 APC2 APLP1 FHOD3 PODXL2 SMIM28 PCSK1N	1.26e-05	198	173	7	50504a3871f76d6a5b439a56450d7770f4501eb0
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LIMA1 ANK2 MAP1A NDN PTPRS FGFR1 NOVA1	1.31e-05	199	173	7	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	Tracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PODXL2 TACC2 RAB11FIP1 RASEF PCSK1N MUC5AC WNK4	1.31e-05	199	173	7	f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW1 MTSS1 TACC2 CSPG4 NAV1 FGFR1 PDZD2	1.31e-05	199	173	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	LIMA1 ESYT1 PPP1R12B WNK1 PTPRJ PIP4K2A FGFR1	1.31e-05	199	173	7	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MTSS1 TACC2 NDN CSPG4 NAV1 FGFR1 PDZD2	1.35e-05	200	173	7	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMA1 ESYT1 PPP1R12B BICDL1 FGFR1 GJA10	2.89e-05	152	173	6	405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMA1 ESYT1 PPP1R12B BICDL1 FGFR1 GJA10	2.89e-05	152	173	6	06fa7d8acc8f56de00af9bee17884595b300410e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	LIMA1 ESYT1 PPP1R12B BICDL1 FGFR1 GJA10	3.00e-05	153	173	6	b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMA1 ESYT1 PPP1R12B BICDL1 FGFR1 GJA10	3.00e-05	153	173	6	487388082bb596809ba1caf9197626b6814792ab
ToppCell	MS-CD8-memory_CD4\|MS / Condition, Cell_class and T cell subcluster	HIC1 MORN1 APC2 TBC1D2 PIANP SLC14A2	3.11e-05	154	173	6	aec893cf3e1cf90e18a9117183fc7a1f397425a9
ToppCell	COVID-19_Severe-Lymphoid_T/NK-dn_T\|COVID-19_Severe / Disease group, lineage and cell class	LIMA1 ESYT1 PPP1R12B BICDL1 FGFR1 GJA10	3.34e-05	156	173	6	83f25683e0f55472b56f915ee176fc05efc33a31
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDC42BPG MORN1 SLC4A3 ARHGAP8 SLC14A2 CCDC40	3.59e-05	158	173	6	ab707bfe782c667b252b488ad1d7efd49cf0a899
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CHD9 PPP1R15A RAB11FIP1 PRDM4 RERE	4.27e-05	163	173	6	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SETD1B PTPRF PRPF40B WDR6 CPLANE1 IMPG2	4.73e-05	166	173	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 ZKSCAN7 IRAG1 PTPRF PTPRS EPHA2	4.73e-05	166	173	6	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 ZKSCAN7 IRAG1 PTPRF PTPRS EPHA2	4.73e-05	166	173	6	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	Control\|World / group, cell type (main and fine annotations)	TACC2 RAB11FIP1 FREM2 RASEF MUC5AC PDZD2	5.05e-05	168	173	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	MAP1A SORBS1 SLC4A3 PTPRS EPHA2 ZBTB3	5.05e-05	168	173	6	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMSAP3 PTPRF PTPRS EPHA2 FGFR1 MUC5AC	5.22e-05	169	173	6	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYCP2L ERN1 MAP1A CERS6 RFTN1 PTPRS	6.34e-05	175	173	6	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	GBX2 DBP ZFP36 IER2 ZBTB7A MUC5AC	6.34e-05	175	173	6	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HECW1 APC2 APLP1 FHOD3 GPR179 SMIM28	6.54e-05	176	173	6	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HECW1 APC2 APLP1 FHOD3 GPR179 SMIM28	6.54e-05	176	173	6	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE NDN ZFP36 IER2 PCSK1N	6.54e-05	176	173	6	3027d34fd663c8a08544d469183dc45138916749
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ERN1 APLP1 NPHP4 MAP3K5 SLC45A1 LY9	6.75e-05	177	173	6	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	APLP1 NPHP4 MAP3K5 SLC45A1 LY9 PSD4	6.96e-05	178	173	6	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP1 CPE PIANP NAV1 PCSK1N FGFR1	7.41e-05	180	173	6	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A PODXL2 CPE IRAG1 SLC4A3 CSPG4	7.41e-05	180	173	6	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PODXL2 CPE SORBS1 PTPRF PTPRS SEC61A1	7.41e-05	180	173	6	e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYCP2L ERN1 MAP1A SLC4A3 PTPRS EPHA2	7.87e-05	182	173	6	02c0824373a0ecebc922d4ca848ace9d570722c4
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B SORBS1 IRAG1 HEPH IER2 FREM2	7.87e-05	182	173	6	7b86703559438e2d5ef3dad963ee0d772513f313
ToppCell	droplet-Kidney-nan-18m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 CPE FOXA2 EPHA2 RASEF SLC14A2	7.87e-05	182	173	6	9fc2f84bf70ad9a11c8a7326bd101e6f6cbcc33e
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	RAB11FIP1 BICDL1 PTPRF SSH3 COQ9 PDZD2	7.87e-05	182	173	6	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APLP1 FOXA2 SLC4A3 ZNF446 KMT2D BLCAP	7.87e-05	182	173	6	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APLP1 FOXA2 SLC4A3 ZNF446 KMT2D BLCAP	7.87e-05	182	173	6	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APC2 APLP1 FHOD3 GPR179 SMIM28 ECE2	8.11e-05	183	173	6	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	ARID4B CHD9 ZNF217 PPP1R15A ZFP36 PARP10	8.11e-05	183	173	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SYCP2L MAP1A CERS6 SLC4A3 PTPRS EPHA2	8.11e-05	183	173	6	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PPP1R12B SORBS1 ANKRD20A3P IRAG1 ANKRD20A4P ANKRD20A1	8.36e-05	184	173	6	39168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ANK2 PPP1R12B TACC2 SORBS1 ANKRD2 PDZD2	8.36e-05	184	173	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 PPP1R12B FHOD3 TACC2 SORBS1 ANKRD2	8.61e-05	185	173	6	549eeb521c3985bff396ea0f202db21822efa51f
Drug	GBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A	MKRN3 NDN SORBS1 PPP1R15A ABCA7 ZFP36 IER2 ZNF750 PTPRS FGFR1 ZNF646	1.80e-07	187	171	11	3240_UP
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	ABL1 ARID4B CHD9 ZNF217 GMEB2 RREB1 KMT5B SETD5 NPAT	1.09e-05	184	171	9	2321_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT_HG-U133A	ARHGAP32 SETD1B ARID4B CHD9 GBX2 ZNF217 FOXA2 IER2 NPAT	1.09e-05	184	171	9	4610_DN
Drug	Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A	CNKSR1 APLP1 PPP1R15A ABCA7 ZFP36 IER2 KMT2D PTPRS DOP1B	1.47e-05	191	171	9	2627_UP
Drug	Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A	HECW1 ZKSCAN7 ABCA7 SLC4A3 TRIM3 BICDL1 NOVA1 IMPG2 ZNF646	1.74e-05	195	171	9	6063_UP
Drug	Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	HECW1 TBC1D2 SLC13A3 NDN DBP MAP3K5 BICDL1 DOP1B CCDC40	1.74e-05	195	171	9	4123_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A	ZNF536 MORN1 TBC1D2 AIRE SORBS1 ZNF446 TRIM3 FGFR1 ADGRD2	1.89e-05	197	171	9	2238_UP
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A	ARHGAP32 SETD1B GRWD1 TACC2 ZFP36 PIP4K2A FGFR1 NOVA1 DOP1B	1.89e-05	197	171	9	7138_DN
Drug	8 lg	MTSS1 RERE IMMT	2.27e-05	8	171	3	CID000028115
Disease	Malignant neoplasm of breast	HIC1 DDX59 ABL1 ANK2 PPP1R12B APC2 PCDHB15 BIRC2 TACC2 SORBS1 WNK1 NCOR1 KMT2D FGD5 FGFR1 ZBTB3 ZNF646	9.96e-05	1074	163	17	C0006142
Disease	glaucoma (is_marker_for)	HEPH RFTN1 MUC5AC	1.76e-04	20	163	3	DOID:1686 (is_marker_for)
Disease	Pseudohypoaldosteronism type 2A	WNK1 WNK4	1.81e-04	4	163	2	cv:C1840389
Disease	Pseudohypoaldosteronism, type 2	WNK1 WNK4	1.81e-04	4	163	2	cv:C1449844
Disease	transient cerebral ischemia (biomarker_via_orthology)	ANK2 PPP1R15A WNK1 MAP3K5 FGFR1 WNK4	2.46e-04	157	163	6	DOID:224 (biomarker_via_orthology)
Disease	migraine disorder, type 1 diabetes mellitus	RERE SLC45A1	3.00e-04	5	163	2	MONDO_0005147, MONDO_0005277
Disease	azoospermia (implicated_via_orthology)	CDC42BPG PTPRF PTPRS	4.39e-04	27	163	3	DOID:14227 (implicated_via_orthology)
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK1 WNK4	4.48e-04	6	163	2	DOID:4479 (implicated_via_orthology)
Disease	pseudohypoaldosteronism (is_implicated_in)	WNK1 WNK4	8.31e-04	8	163	2	DOID:4479 (is_implicated_in)
Disease	cognitive function measurement, self reported educational attainment	ATXN7L2 BIRC6 ITIH1 PTPRF PTPRJ BSN NOVA1 NPAS1	8.38e-04	355	163	8	EFO_0004784, EFO_0008354
Disease	Pseudohypoaldosteronism, Type I	WNK1 WNK4	1.33e-03	10	163	2	C0268436
Disease	Pseudohypoaldosteronism	WNK1 WNK4	1.33e-03	10	163	2	C0033805
Disease	Hyperpotassemia and Hypertension, Familial	WNK1 WNK4	1.33e-03	10	163	2	C2713447
Disease	Pseudohypoaldosteronism, Type I, Autosomal Recessive	WNK1 WNK4	1.33e-03	10	163	2	C1449843
Disease	Pseudohypoaldosteronism, Type II	WNK1 WNK4	1.33e-03	10	163	2	C1449844
Disease	Pseudohypoaldosteronism, Type I, Autosomal Dominant	WNK1 WNK4	1.33e-03	10	163	2	C1449842
Disease	autism spectrum disorder (implicated_via_orthology)	ARHGAP32 CHD9 PIANP KMT5B PAK2	1.59e-03	152	163	5	DOID:0060041 (implicated_via_orthology)
Disease	thrombin generation potential measurement	SYCP2L PTPRJ	1.61e-03	11	163	2	EFO_0005538
Disease	revision of total hip arthroplasty, aseptic loosening	VCX2 TBC1D2 VCX3B	1.62e-03	42	163	3	EFO_0010725, EFO_0020973
Disease	Royer Syndrome	MKRN3 NDN	1.93e-03	12	163	2	C0265222
Disease	Gastric Adenocarcinoma	ERN1 EPHA2 MAP3K9	1.98e-03	45	163	3	C0278701
Disease	myeloid white cell count	LIMA1 ABL1 SETD1B RREB1 PNKD ABCA7 MAP3K5 ZBTB7A GTF3C1 PTPRJ PAK2 ADGRD2 RERE	2.18e-03	937	163	13	EFO_0007988
Disease	reticulocyte measurement	ZNF217 PPP1R15A RREB1 PNKD BIRC6 MAP3K5 PTPRJ ZNF792 UBAC1 PAK2 ADGRD2 SLC45A1 BSN PDZD2	2.19e-03	1053	163	14	EFO_0010700
Disease	Prader-Willi Syndrome	MKRN3 NDN	2.27e-03	13	163	2	C0032897
Disease	Mammary Carcinoma, Human	HIC1 ABL1 PPP1R12B APC2 BIRC2 NCOR1 KMT2D FGD5 FGFR1	2.67e-03	525	163	9	C4704874
Disease	Mammary Neoplasms, Human	HIC1 ABL1 PPP1R12B APC2 BIRC2 NCOR1 KMT2D FGD5 FGFR1	2.67e-03	525	163	9	C1257931
Disease	Mammary Neoplasms	HIC1 ABL1 PPP1R12B APC2 BIRC2 NCOR1 KMT2D FGD5 FGFR1	2.74e-03	527	163	9	C1458155
Disease	lymphocyte count	LIMA1 ABL1 PHF23 ZNF217 CERS6 DBP RREB1 TYK2 NCOR1 ZBTB7A PTPRJ PAK2 ADGRD2 RERE LY9 RAD9A PSD4	3.13e-03	1464	163	17	EFO_0004587
Disease	Breast Carcinoma	HIC1 ABL1 PPP1R12B APC2 BIRC2 NCOR1 KMT2D FGD5 FGFR1	3.14e-03	538	163	9	C0678222
Disease	Metastatic melanoma	PASK MAP3K9 WNK4	3.34e-03	54	163	3	C0278883
Disease	Glioblastoma Multiforme	CDC42BPG ERN1 NCOR1 ZBTB7A	3.40e-03	111	163	4	C1621958
Disease	caudal anterior cingulate cortex volume measurement	HECW1 FAT2	3.91e-03	17	163	2	EFO_0010289
Disease	lymphocyte measurement	ERN1 ABCA7 RERE LY9	4.10e-03	117	163	4	EFO_0803546
Disease	Polydactyly	DDX59 FREM2 FGFR1 CPLANE1	4.10e-03	117	163	4	C0152427
Disease	migraine disorder, systolic blood pressure	HIC1 IRAG1	4.38e-03	18	163	2	EFO_0006335, MONDO_0005277
Disease	Tourette syndrome, schizophrenia	ZNF536 RERE	4.38e-03	18	163	2	EFO_0004895, MONDO_0005090
Disease	colorectal cancer (is_implicated_in)	AMER1 ABL1 IER2 PTPRJ	4.62e-03	121	163	4	DOID:9256 (is_implicated_in)
Disease	loneliness measurement	CHMP4A PTPRJ RASEF RERE	5.04e-03	124	163	4	EFO_0007865
Disease	glucose measurement	ERN1 CERS6 RREB1 FOXA2 CHMP4A PTPRJ BSN	5.34e-03	380	163	7	EFO_0004468
Disease	citrulline measurement	HMCN2 RP1L1	5.40e-03	20	163	2	EFO_0009777
Disease	reticulocyte count	ZNF217 GMEB2 PPP1R15A RREB1 PNKD BIRC6 PTPRJ ZNF792 UBAC1 ADGRD2 SLC45A1 BSN PDZD2	5.46e-03	1045	163	13	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
VPEKVSEPLPGSSHE	ANKRD20A1	301	Q5TYW2
DSDTEAAASPPHPAP	ARID4B	946	Q4LE39
PHPAPEEGVAEESLQ	ARID4B	956	Q4LE39
EEPELSGGPPHITSS	ESYT1	936	Q9BSJ8
GESEAEPVEPPHSGT	SLC4A3	146	P48751
STHLPAGPAPKVDED	CHMP4A	196	Q9BY43
DEPLTHDITGAPPLS	BIRC6	2461	Q9NR09
HLEATLEEAGPSPPT	CSPG4	806	Q6UVK1
VDVGETGPSPPIHSK	BSDC1	321	Q9NW68
PSHGSNPIEDPLEAE	BRD8	586	Q9H0E9
VPEKVSEPLPGSSHE	ANKRD20A4P	301	Q4UJ75
DPEPSGEPLTDLHSH	GJA10	391	Q969M2
PHPELKATDSQPTEG	FCRL4	191	Q96PJ5
HSEHLGPSELEAPAP	APLP1	486	P51693
PEASSLEEPHSPETG	AMER1	276	Q5JTC6
LFTPPVIGSHPDESG	POLE2	146	P56282
DPGEHPQAEPGSLAE	BICDL1	71	Q6ZP65
AVTFSPDLGPVPHEG	CAMSAP3	681	Q9P1Y5
APDKTEVTGDHIPTP	ARPP19	81	P56211
SEEEGTSDDLHPPPD	ATXN7L2	386	Q5T6C5
LGPEDSSDPTEHPTP	ABCA7	441	Q8IZY2
APGPAKDDTASHEPA	AIRE	496	O43918
VTVPAGAAPGPEEHT	GMEB2	501	Q9UKD1
LDPAPAVSEAGPETH	RASEF	86	Q8IZ41
SPGPHSEEEDEAEPS	RAD9A	336	Q99638
PESNPLEVHEEPLSG	RFTN1	261	Q14699
DVDDDTLNHPGTLPP	CDC42BPG	366	Q6DT37
EDSGDEDPSSHPATP	NPAS1	476	Q99742
ESPESHETPETPFVG	KIAA1107	706	Q9UPP5
EGTPVENSHSLPPES	NPAT	691	Q14207
VPEKVSEPLPGSSHE	ANKRD20A2P	301	Q5SQ80
GGSPIIQEPEEPSEH	ANK2	3821	Q01484
APAGPTFEEPGTVHI	ARL10	221	Q8N8L6
AGQPPHVLEEGPEAS	MORN1	466	Q5T089
QTTAPSGAEHPDEDP	PODXL2	311	Q9NZ53
DITEEGTSHSPPEPE	OGFOD1	386	Q8N543
APVHDESLVGPVDPS	PTPRJ	306	Q12913
HVPSTLDAGPEDTCP	PASK	846	Q96RG2
PGAITSPDEHILTPD	MAP1A	1306	P78559
EEEGPSTSPDPAHLE	MAGEA8	91	P43361
ETPHSPGVEDAPIAK	LIMA1	486	Q9UHB6
LHGTKPPPSEGSDEE	GRWD1	111	Q9BQ67
EVSDIHPGSDPTKPD	ITIH1	841	P19827
AGPEAHTPDITKAEP	GPR179	1366	Q6PRD1
EETGSSEDPSPPGGH	HIC1	401	Q14526
DREEPEGATPGTAHP	HECW1	616	Q76N89
PFHDPDIGPVTLTAD	HMCN2	81	Q8NDA2
AVPEPQESGSEEHLP	DOP1B	1041	Q9Y3R5
PVHDSPGKDDAVPDL	KMT5B	631	Q4FZB7
PTDTDENHLPAPLGT	FREM2	746	Q5SZK8
EQLDSAGVTGPHPPS	BSN	706	Q9UPA5
SPEQGAKDSHPSEEP	DDX59	76	Q5T1V6
PESSHEGLVTDPHSP	ECE2	761	P0DPD6
EADVSSPHPGEPNVP	IRAG1	231	Q9Y6F6
PPEESKSGEATADHP	GPATCH8	1206	Q9UKJ3
AADHDVGSELPPEGV	PCSK1N	221	Q9UHG2
TEHSVQVPEDAPPGT	FAT2	3221	Q9NYQ8
SAPHAAEAGSPESPE	IGFBP1	111	P08833
GPEERGEHSPESPSV	MTSS1	636	O43312
AVDESTVPPDHSPPE	PDZD2	51	O15018
VPHPEDDHSQVEGPE	PDXDC1	771	Q6P996
TVPEETGPEAGSSAP	FGD5	496	Q6ZNL6
RGAPHPESEPESSEE	KIAA2012	441	Q0VF49
TDHPEIGEGKPTPAL	IMMT	171	Q16891
APGDTQHSEEAEPEP	MUC5AC	5621	P98088
SVPEGPFPGHLVDVS	PCDHB15	726	Q9Y5E8
NCDHPLPETTATGDP	ARHGAP32	1116	A7KAX9
SEEHLDAPTEPVSGP	NPHP4	451	O75161
SVPEGPFPGHLVDVS	PCDHB12	726	Q9Y5F1
TVAHTEVGPGPESSP	PTPRS	696	Q13332
SVPEGPFPGHLVDVS	PCDHB14	726	Q9Y5E9
PVPAPVGDSHVDGAA	PAK2	201	Q13177
VPEKVSEPLPGSSHE	ANKRD20A3P	301	Q5VUR7
AASHEPPPEPEEITG	ANKRD2	131	Q9GZV1
EDPETEVPTHPEDGT	APC2	251	O95996
PTPPGAGVKEEHDQS	CHD9	2316	Q3L8U1
EEDPGHALEETPPSS	GBX2	221	P52951
SDSPLPESAHDPGVV	BLCAP	71	P62952
SESTHPEGPEEEENP	E2F6	256	O75461
LSPTEEEEPEHPFGV	CPLANE1	3141	Q9H799
THVEEPAFLPDPNDG	ERN1	66	O75460
GEDSVFSHEPLPEEP	FGFR1	791	P11362
LECPEHTLPSPEGAT	EPHA2	291	P29317
EDGQSASRHPEPVPE	ATG9A	811	Q7Z3C6
ASRHPEPVPEEGSED	ATG9A	816	Q7Z3C6
VTSPEPSHGVLGPSE	CCDC40	156	Q4G0X9
HPQASAGDPEPESEA	FHOD3	551	Q2V2M9
IELSDNPGVHEPGEP	CPE	91	P16870
QGESDPLDHEPAVSP	ABL1	556	P00519
EGAPATAPEPHSLGI	ABCG5	26	Q9H222
SSDEEDSEPPGKNPH	CERS6	346	Q6ZMG9
PEPPGALASHDQDTL	EFS	266	O43281
QAEAPADTPEPTAGH	LY9	491	Q9HBG7
EPDPADLALSSIPGH	DBP	206	Q10586
QGAEKPDPESSHSPP	COQ9	66	O75208
HPGETEVPLDLPADS	SLC13A3	206	Q8WWT9
ESPERGGPAEVVHDS	SCAP	596	Q12770
LPEEGPGDSLPSHTA	SLC45A1	351	Q9Y2W3
QEESPSHFTAVPGEP	KIFC2	161	Q96AC6
GPSSDGIHEEPTPVN	MAP3K9	711	P80192
LQPDTPDCAGDSHTP	AUNIP	156	Q9H7T9
EGESDGTHPVGTPPD	PIP4K2A	301	P48426
SDCPEHGPVTFVPDT	PRDM4	386	Q9UKN5
LGEAESDPHPSHPDQ	PPP1R15A	461	O75807
AHTDVGPGPESSPVL	PTPRF	686	P10586
TPGHEEEEPVAPSTV	PARP10	631	Q53GL7
VNPDGSPSSLDPPEH	UPF2	901	Q9HAU5
GTHTGVPIDLDPPDS	NOVA1	11	P51513
SVPEGPFPGHLVDVS	PCDHB9	726	Q9Y5E1
AETATPDGEHPFPEP	IER2	81	Q9BTL4
AGPASETPAGTESPH	FOXA2	291	Q9Y261
EDHSAPPSPEEKDSG	MAP3K5	1026	Q99683
VGTDVTEGPAHPAPH	NAV1	1276	Q8NEY1
GNASDGEPPESPHAE	RAB11FIP1	846	Q6WKZ4
PEEPVSEGTQHDPLS	VCX3A	91	Q9NNX9
EPLKHESPAAPSSAG	TEX55	11	Q96M34
LQSHSSPEGKEEPEP	PNKD	41	Q8N490
VPHSDVGEPPASTGA	SRRM2	2501	Q9UQ35
PEEPVSEGTQHDPLS	VCX3B	91	Q9H321
PEEPVSEGTQHDPLS	VCY	91	O14598
AFGDSPTPTPDHEEP	PIANP	241	Q8IYJ0
TIPEGHAPTDADPAC	HEPH	166	Q9BQS7
QEHSAEEGSVCDPPP	NCOR1	801	O75376
PGDTGLHSSPPENED	PSD4	196	Q8NDX1
PQLATPGSSHPGEEE	SETD5	866	Q9C0A6
FSIDLPEHPPAGEVT	SMIM28	86	A0A1B0GU29
ESSPAGPEKPHDSLD	SETD1B	486	Q9UPS6
PFPSPDGDTVTQHEE	RERE	301	Q9P2R6
IPTSPEGVAPTSGHD	STARD9	3571	Q9P2P6
DRSTHFPEEEPLSGP	IMPG2	671	Q9BZV3
GGVSPEEHPAPEVST	SSH3	481	Q8TE77
ADPPIIHFGPGESSS	BIRC2	371	Q13490
PDPLSEVHGALSPAE	ADGRD2	391	Q7Z7M1
HPAVAESAVVGSPDP	ACSM1	491	Q08AH1
DPDDEAGSHSASPSP	CNKSR1	526	Q969H4
EDGPSHPETKPGSLD	ZNF750	591	Q32MQ0
PEEPVSEGTQHDPLS	VCX2	91	Q9H322
EPSGESAAPDSALPH	MKRN3	36	Q13064
GGPSTAAHIEPPTQE	MKRN3	141	Q13064
GTEEPTEPPSHLSET	RP1L1	1446	Q8IWN7
HGPSDEEQGSPPEDK	RREB1	1216	Q92766
SPPESFGSVLEDPVH	SEC61A1	346	P61619
PSGAEDIDLNSPDHP	TEX54	56	A0A1B0GVG6
TPPAEGEGHEAPIAK	SH3PXD2A	361	Q5TCZ1
QSEPPVIGEPASDSH	SYCP2L	466	Q5T4T6
HESKPGLEPEPSSAD	SORBS1	96	Q9BX66
DPFSKEEGAAPSPTH	SNX15	216	Q9NRS6
LSLSPDVPVPSDHGG	ZFP36	11	P26651
DVPVPSDHGGTESSP	ZFP36	16	P26651
ESPQDPSGESPHGAE	ZNF646	706	O15015
PTELPHPSEGNDEKA	TMUB2	96	Q71RG4
HSPSGSESEEEELPP	PRPF40B	711	Q6NWY9
PPGPTDGAKVHEDST	TACC2	546	O95359
SEPFSNPLAPDGHDV	IK	6	Q13123
SPLGFSHAAPEEDTP	TNXA	16	Q16473
SHAAPEEDTPAPELA	TNXA	21	Q16473
DHDSTVLEPPVDPGL	WDR6	951	Q9NNW5
ATVHPEGVPPADSES	PHF23	286	Q9BUL5
PEEPVSEGTQHDPLS	VCX	91	Q9H320
IFSTPEAPGEHGLAP	ARHGAP8	411	P85298
TEEPLGSPHPSGTVE	ZNF446	131	Q9NWS9
SSAEPEAEPHLSGPV	ZNF536	11	O15090
AASSPSVFPGLHEEP	ZIC4	36	Q8N9L1
TPSDGEPHEATEGVV	ZNF792	231	Q3KQV3
GEHPPLSSSPVEHEG	ZKSCAN7	361	Q9P0L1
DVTPPPDGSTTHNLE	ZNF217	646	O75362
HAEDPTIDTPLPGQA	UBAC1	231	Q9BSL1
LSEPSHLNGPSSDPE	WNK1	2001	Q9H4A3
SSEDSPPEGQAPPSH	GTF3C1	1841	Q12789
HPPTAGPKVEEGSEA	SLC14A2	456	Q15849
PGGQESPSPHTAEVE	WNK4	971	Q96J92
AGSGSTPSEPHPVLE	YTHDF2	376	Q9Y5A9
DGPIGIPFPDHSSDI	ZBTB7A	6	O95365
TGHEPPGEDSPQSGE	TBC1D2	231	Q9BYX2
AHDPEDPHPLSVVAG	TRIM3	96	O75382
TDPGPESAAGPPTHE	TYK2	301	P29597
EEVGPSDHFLPTDPH	ZBTB3	406	Q9H5J0
PSATESDLPNPHVGE	KMT2D	26	O14686
GSPEKHEPSAVPATE	PPP1R12B	686	O60237
EVHSSPGVSEGVPPS	NDN	21	Q99608