Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A9 SLC22A10

1.01e-045642GO:0015636
GeneOntologyBiologicalProcessnegative regulation of type II interferon production

HLA-DRB1 ZNF683 CR1 PDCD1LG2

2.01e-0551654GO:0032689
GeneOntologyBiologicalProcessT cell differentiation

EOMES FZD8 STK11 JMJD6 HLA-DRB1 AMBRA1 ZNF683 CR1

2.58e-05382658GO:0030217
GeneOntologyBiologicalProcessT cell activation

EOMES FZD8 STK11 JMJD6 HLA-DRB1 AMBRA1 ZNF683 CR1 RAC2 PDCD1LG2

6.38e-057016510GO:0042110
DomainPKD

PKD1L1 PMEL

2.48e-047652PF00801
DomainPKD/Chitinase_dom

PKD1L1 PMEL

4.23e-049652IPR022409
DomainPKD

PKD1L1 PMEL

4.23e-049652SM00089
DomainPKD

PKD1L1 PMEL

6.43e-0411652PS50093
DomainPKD_dom

PKD1L1 PMEL

6.43e-0411652IPR000601
Domain-

PKD1L1 PMEL

6.43e-04116522.60.40.670
DomainRHO

RAC2 RAC3

2.18e-0320652PS51420
Domainzf-C2H2

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

2.69e-03693658PF00096
DomainZINC_FINGER_C2H2_2

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

5.29e-03775658PS50157
DomainZINC_FINGER_C2H2_1

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

5.37e-03777658PS00028
DomainZnf_C2H2

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

6.62e-03805658IPR007087
DomainZnF_C2H2

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

6.76e-03808658SM00355
Pubmed

A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population.

HLA-DRB1 IRF5

3.66e-06267218408250
Pubmed

B7-DC (PD-L2) costimulation of CD4+ T-helper 1 response via RGMb.

RGMB PDCD1LG2

3.66e-06267228479601
Pubmed

Structure and chromosomal assignment to 22q12 and 17qter of the ras-related Rac2 and Rac3 human genes.

RAC2 RAC3

3.66e-0626729299243
Pubmed

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance.

RGMB PDCD1LG2

3.66e-06267224752301
Pubmed

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

HLA-DRB1 HIC2 IRF5

5.46e-061867319838193
Pubmed

Identification of a novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney.

SLC22A9 SLC22A10

1.10e-05367217079864
Pubmed

Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter.

SLC22A9 SLC22A10

1.10e-05367216150593
Pubmed

Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.

RAC2 RAC3

1.10e-05367216081809
Pubmed

Signaling and cytoskeletal requirements in erythroblast enucleation.

RAC2 RAC3

1.10e-05367222461493
Pubmed

Renal expression of organic anion transporter Oat5 in rats and mice exhibits the female-dominant sex differences.

SLC22A9 SLC22A10

1.10e-05367220865662
Pubmed

Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney.

SLC22A9 SLC22A10

1.10e-05367220332632
Pubmed

rac, a novel ras-related family of proteins that are botulinum toxin substrates.

RAC2 RAC3

1.10e-0536722674130
Pubmed

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.

RAC2 RAC3

1.10e-05367222123845
Pubmed

HLA-DRB1, IRF5, and CD28 gene polymorphisms in Egyptian patients with rheumatoid arthritis: susceptibility and disease activity.

HLA-DRB1 IRF5

1.10e-05367234017081
Pubmed

Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What's behind Neuro-RACopathies.

RAC2 RAC3

1.10e-05367234943902
Pubmed

Distinct Roles of Small GTPases Rac1 and Rac2 in Histamine H4 Receptor-Mediated Chemotaxis of Mast Cells.

HRH4 RAC2

1.10e-05367230021868
Pubmed

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.

SLC22A9 SLC22A10

2.19e-05467219417012
Pubmed

Isolation of a family of organic anion transporters from human liver and kidney.

SLC22A9 SLC22A10

2.19e-05467211327718
Pubmed

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

SLC22A9 SLC22A10

2.19e-05467215068970
Pubmed

Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues.

EOMES ZNF683

3.64e-05567234462601
Pubmed

Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis.

EOMES ZNF683

3.64e-05567234183415
Pubmed

PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.

RAC2 RAC3

3.64e-05567222043008
Pubmed

Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1.

HLA-DRB1 IRF5

7.63e-05767220797713
Pubmed

ILC1 Confer Early Host Protection at Initial Sites of Viral Infection.

EOMES ZNF683

7.63e-05767229056343
Pubmed

The yin-yang of PR-domain family genes in tumorigenesis.

PRDM7 PRDM5

7.63e-05767210668202
Pubmed

FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development.

EOMES PLXNA4

7.63e-05767227791111
Pubmed

A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation.

SPRY4 CBL

7.63e-05767216893902
Pubmed

Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes.

EOMES ZNF683

1.02e-04867231810881
Pubmed

Generation and characterization of Rac3 knockout mice.

RAC2 RAC3

1.02e-04867215964829
Pubmed

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

EOMES AMBRA1

1.02e-04867233854232
Pubmed

Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.

RAC2 RAC3

1.02e-04867224598074
Pubmed

RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma.

FZD8 RNF43

1.02e-04867231286874
Pubmed

SET domains and histone methylation.

PRDM7 PRDM5

1.02e-04867214675547
Pubmed

CYBA encoding p22(phox), the cytochrome b558 alpha polypeptide: gene structure, expression, role and physiopathology.

RAC2 RAC3

1.02e-04867227048830
Pubmed

Developmental nonlinearity drives phenotypic robustness.

SPRY4 RICTOR

1.63e-041067229213092
Pubmed

Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates.

SPRY4 CBL

1.63e-041067218273061
Pubmed

Regulation of lymphatic-blood vessel separation by endothelial Rac1.

RAC2 RAC3

1.63e-041067219906871
Pubmed

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

FZD8 RNF43

1.99e-041167222575959
Pubmed

The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation.

RAC2 RAC3

1.99e-041167218786395
Pubmed

Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

SPRY4 CBL

2.38e-041267217974561
Pubmed

Molecular physiology of renal organic anion transporters.

SLC22A9 SLC22A10

2.81e-041367216403838
Pubmed

CbGRiTS: cerebellar gene regulation in time and space.

EOMES PCSK9

2.81e-041367225446528
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA4 RAC2

2.81e-041367211604131
Pubmed

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

SLC22A9 SLC22A10

2.81e-041367215369770
Pubmed

Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner.

EOMES SPRY4

3.28e-041467225446535
Pubmed

Genome-wide association study of pancreatic cancer in Japanese population.

RNF149 RNF43

3.28e-041467220686608
Pubmed

Essential role of Rac1 and Rac3 GTPases in neuronal development.

RAC2 RAC3

3.28e-041467219126596
Pubmed

Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning.

EOMES FZD8

3.78e-041567215302604
Pubmed

Genetic variants in the prediction of rheumatoid arthritis.

HLA-DRB1 IRF5

4.31e-041667220439292
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC22A9 SLC22A10

4.31e-041667219679677
Pubmed

Pluripotency factors regulate definitive endoderm specification through eomesodermin.

EOMES FZD8

4.31e-041667221245162
Pubmed

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.

RGMB PLXNA4 INSM2

4.51e-047767329445148
Pubmed

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

HLA-DRB1 IRF5

4.88e-041767221779181
Pubmed

Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.

RICTOR CBL

6.12e-041967231959764
Pubmed

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

EOMES FZD8

6.12e-041967221822279
Pubmed

Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.

EOMES SPRY4

6.79e-042067223633963
Pubmed

Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.

EOMES RICTOR

7.50e-042167223637172
Pubmed

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.

HLA-DRB1 AMBRA1

8.24e-042267220694011
Pubmed

Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium.

EOMES FZD8

9.82e-042467215858069
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FRMPD1 PCNX1 FAN1

1.02e-0310267310231032
Pubmed

Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development.

FZD8 SPRY4

1.07e-032567221784065
Pubmed

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.

EOMES RICTOR

1.07e-032567228069738
Pubmed

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.

PLXNA4 RAC3

1.15e-032667239152101
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

JMJD6 AMBRA1 RICTOR HIC2 C11orf16 PRDM5 TEP1 RNF43

1.34e-03111667831753913
Pubmed

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

EOMES HLA-DRB1

1.44e-032967222190364
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD8 EFNA3 PLXNA4

1.52e-0311767317145500
Pubmed

Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.

EOMES RICTOR

1.54e-033067222056141
Pubmed

Correct patterning of the primitive streak requires the anterior visceral endoderm.

EOMES FZD8

1.54e-033067221445260
Pubmed

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.

PLXNA4 NOSTRIN

1.54e-033067219401682
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

PCNX1 RNF43

1.86e-033367219336002
InteractionMYOF interactions

MEX3A SPRY4 RICTOR RAC2 RAC3

1.81e-05102645int:MYOF
InteractionSTXBP3 interactions

RNF149 RICTOR STRA6 RAC2 RAC3

1.99e-05104645int:STXBP3
InteractionMAP3K11 interactions

CBL MAP4K2 RAC2 RAC3

3.95e-0560644int:MAP3K11
InteractionZNF287 interactions

KLF15 ZNF770 PRDM5 ZNF445

3.95e-0560644int:ZNF287
InteractionALDH3A2 interactions

RNF149 WSB2 ADCK2 CBL RNF43 RAC2 RAC3

4.94e-05304647int:ALDH3A2
InteractionANKLE2 interactions

MEX3A RNF149 RNF43 RAC2 RAC3 FAN1

5.40e-05210646int:ANKLE2
InteractionZDHHC8 interactions

RNF43 RAC2 RAC3

7.54e-0526643int:ZDHHC8
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

KLF15 INSM2 ZNF770 ZNF683 HIC2 PRDM7 PRDM5 ZNF445

4.07e-0471846828
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM7 PRDM5

8.41e-04174621197
GeneFamilyRho family GTPases

RAC2 RAC3

1.17e-0320462390
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN

NAPSA B3GNT6 KLHDC1 RNF43 RAC2 PDCD1LG2

1.24e-05200676M7150
CoexpressionAtlaslung

NAPSA SHROOM4 HLA-DRB1 C11orf16 CD300C PCSK9

1.81e-05182646lung
CoexpressionAtlasMyeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1

NAPSA CSGALNACT2 HLA-DRB1 RNF149 ZNF770 IRF5 NOSTRIN PDCD1LG2

1.87e-05382648GSM538248_500
CoexpressionAtlasMyeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3

NAPSA CSGALNACT2 HLA-DRB1 RNF149 ZNF770 IRF5 NOSTRIN PDCD1LG2

2.21e-05391648GSM538249_500
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES EFCAB6 ZNF683 RAC2 PDCD1LG2

2.95e-061486757cb4865a1e9522e24f9c14799568b67172bd99dc
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

SHROOM4 SLC22A9 PKD1L1 SLC22A10 NOSTRIN

4.32e-06160675958256e3d3836160763b82bb48f794087918d935
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CSGALNACT2 RNF149 IRF5 TEP1

5.48e-0616867500cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CSGALNACT2 RNF149 IRF5 TEP1

5.64e-0616967590c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellwk_20-22-Hematologic-Myeloid-pre-pDC/DC5|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NAPSA HLA-DRB1 IRF5 LTB4R2 CD300C

7.06e-061776756de3c623f8595d7e3827df99b806bc9f1f15b3b7
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

CSGALNACT2 JMJD6 HLA-DRB1 RNF149 RICTOR

1.10e-05194675d1366b169d14011194e61d16b6b0953349febc78
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 IRF5 CR1 CD300C RAC2

1.13e-051956754387e27d2288fb46a9ed110464542a4aea402358
ToppCell5'-Adult-LymphNode-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA HLA-DRB1 IRF5 CR1 RAC2

1.13e-05195675e98217f9cf8c9574af66a1d8953101119c89c8a1
ToppCellwk_08-11-Hematologic-Myeloid-Myelocyte-like|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

METTL25B CSGALNACT2 ZNF770 IRF5 RAC2

1.16e-051966754b88c96b737a747422674ad99c073b28e6febc7c
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CSGALNACT2 RNF149 PCNX1 CR1 RAC2

1.19e-051976751acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

RGMB MEX3A PLXNA4 HIC2 RAC3

1.27e-05200675c92e4fc0442404481fcac623d691dae6215b852d
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-Uncommitted_AE_Progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

NAPSA ADAMTSL1 EFCAB6 RNF43

3.57e-051236745f002f5180fe47fe57ab888b5f0319df99ab2c59
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

6.25e-0514267439ada235a46f2202c093cf2336de224a5957ed1a
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES ZNF683 RAC2 PDCD1LG2

7.93e-051516741525422afadff68a1525ced6d5db45fdea450678
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

8.13e-05152674bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 LTB4R2 RAC2

8.13e-05152674254f92d9e6c9c6404f3875dd54d655af87854b14
ToppCellfacs-Aorta-Heart-24m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

8.13e-05152674525d65c5c8e5580947367afdb1f6e68b49e9e5bb
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA KLHDC1 CD300C PDCD1LG2

8.99e-051566745d97755db872d51522f6412a93704f3c79a084cd
ToppCellPND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NAPSA IRF5 CBL RAC2

8.99e-05156674166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCellPND07-28-samps-Myeloid-Granulocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NAPSA IRF5 CBL RAC2

8.99e-051566745e1c5a7c9293b886920739cf766521df7f69726c
ToppCellfacs-MAT-Fat-18m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES ADCK2 RNF43 RAC2

9.22e-05157674e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCellfacs-Aorta-Heart-24m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

9.68e-05159674443f6df4a88fa8755adcde4cc12575dff614ecb4
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 RAC2

9.92e-051606746329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES NAPSA IRF5 RAC2

1.02e-0416167416f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 CD300C

1.02e-04161674787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES NAPSA IRF5 RAC2

1.02e-04161674f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 CD300C

1.02e-041616743db97af49520dc8cbafb4454d8afd9d588160e89
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 CD300C

1.02e-04161674f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES NAPSA IRF5 RAC2

1.02e-0416167458a32a1033f379579697bda1bbf047a088e4a34f
ToppCellImmune_cells-B_cell|World / Lineage and Cell class

NAPSA IRF5 RAC2 PDCD1LG2

1.07e-041636743a02465de7c2f7cea227e289fb082a1fb6400301
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CSGALNACT2 RNF149 IRF5

1.09e-04164674cd0794f84dfd346807e2d803723718b7f22e9232
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHDC1 IRF5 PMEL RAC2

1.09e-04164674b175258fb0885afd84d4a414c0ae441f880e8469
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CSGALNACT2 RNF149 IRF5

1.09e-0416467412251a49fd4af32d4edb58046245548c260cf04b
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 CD300C

1.09e-04164674b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHDC1 IRF5 PMEL RAC2

1.09e-04164674875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHDC1 IRF5 PMEL RAC2

1.09e-041646748bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

SHROOM4 SPRY4 PMEL LTB4R2

1.12e-04165674ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 RAC2 PDCD1LG2

1.14e-041666748e5a262dc4f04c5fc75b9a7a907832a0d7877df0
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 CD300C RAC2

1.14e-04166674e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCellfacs-GAT-Fat-24m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.17e-041676745d9ffbcb539d9c50cef9dd792ea11aa37dd2c1df
ToppCellfacs-Heart-LV-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CD300C RAC2 PDCD1LG2

1.17e-041676744a669eafde3582a451614ad304769b47aa1d9578
ToppCellfacs-GAT-Fat-24m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.17e-04167674c31e41fb76ba261ac546fac3cc2b8337e39bfa86
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT6 FZD8 PLXNA4 PMEL

1.17e-041676742812353ff66e76f10bd327ceb0e6b009502a5258
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF43 RAC2 PDCD1LG2

1.17e-041676748ce8d93c79ac6a3f52252b4cec53378c362bfe0a
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF43 RAC2 PDCD1LG2

1.17e-041676748340f7075d00dccb304cfd4c9b5711ca6dbf7cce
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT6 FZD8 PLXNA4 PMEL

1.17e-04167674d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCellfacs-GAT-Fat-24m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.17e-04167674a04d1f2413fd24ad5e9cc67312220606157fecf3
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 CD300C RAC2

1.20e-0416867484977db9d71e59208727885320cc18d80d064380
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 TEP1 RAC2

1.20e-04168674ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 TEP1 RAC2

1.20e-04168674af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BCLAF3 FZD8 ANKFY1 ETFDH

1.22e-04169674665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CD300C RAC2 PDCD1LG2

1.22e-04169674ae85cef7ef8f761c19f4af2a23fe333641c38a92
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CD300C RAC2 PDCD1LG2

1.22e-04169674c01bc3f2f299109086ded83dc11e98559bf1940c
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BCLAF3 FZD8 ANKFY1 ETFDH

1.22e-041696746614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellfacs-SCAT-Fat-24m-Myeloid-myeloid_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.25e-0417067413480e5f2de50425e42be0144b876e9aa4006a68
ToppCellfacs-SCAT-Fat-24m-Myeloid-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.25e-04170674d22cd09a43a14045bb1181189fe8accf78fdde3b
ToppCellfacs-SCAT-Fat-24m-Myeloid|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 RAC2

1.25e-04170674f9968d3735328a39157764343dd40f1ad8bf710d
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 TEP1 RAC2

1.28e-0417167487cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 RAC2

1.28e-041716744ad28ecfde3d529a09b80be908c446bd5274518e
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPRY4 PLXNA4 RICTOR RAC3

1.28e-04171674714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCelldroplet-Lung-21m-Hematologic-myeloid|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.28e-0417167422ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES RNF43 RAC2 PDCD1LG2

1.28e-041716744198e7fef1aaee3d85722094f3e444655d393e9e
ToppCelldroplet-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

1.31e-04172674f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCelldroplet-Lung-nan-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 TEP1

1.31e-0417267435d09640d5b04fa0bbb1b40d4b8f97da587a5046
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 TEP1 RAC2

1.31e-04172674cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 TEP1 RAC2

1.31e-04172674f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC2|bone_marrow / Manually curated celltypes from each tissue

NAPSA HLA-DRB1 IRF5 CD300C

1.31e-0417267464928cea7e5b60e4bc4af016454b0173ebcc07c7
ToppCelldroplet-Lung-nan-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 TEP1

1.31e-0417267498cb64e2a768908105701a7a5b58f336036250fd
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.31e-04172674a53c906539557594ef10368bc29aec4af063fd37
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES RNF43 RAC2 PDCD1LG2

1.31e-04172674a3bcf0d432d8fccce50248e8d0c7a4804d69bfee
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES RNF43 RAC2 PDCD1LG2

1.31e-04172674976d27edd5608616830624907fe050fcd3551865
ToppCellfacs-Trachea-nan-24m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 RAC2 PDCD1LG2

1.34e-0417367471c90c57225e452c73bf7bea46b454c472bf5f76
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.34e-041736749acad7ec70f713fe3db6cef7bbe3b183bf16ae67
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCLAF3 CSGALNACT2 ETFDH CD300C

1.37e-04174674ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF149 LTB4R2 CD300C RAC2

1.40e-04175674e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA HLA-DRB1 CR1 RAC2

1.40e-04175674d544f24ee33783ed4afb4d7ec079a4484118bb15
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF5 TEP1 RAC2 RAC3

1.40e-0417567443b9cfd7c47d57244565c641e57f3256b5900804
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF5 TEP1 RAC2 RAC3

1.40e-04175674a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF5 TEP1 RAC2 RAC3

1.43e-041766741df640f88667e2dad30e65279d6d33bba75024c1
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA RNF149 IRF5 TEP1

1.43e-041766741bf8fed48bd224f09efe90a38233b1f01d7311fe
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA IRF5 TEP1 RAC2

1.43e-04176674a85ad8b4815fde72edd5c900e882a0bc04033ea8
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 IRF5 CR1 RAC2

1.49e-041786742e51c1596022b7047994ee13c18375bad19a54a5
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.53e-0417967466afd54428e6dcadc3e341faecfde42be4fb5905
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 IRF5 RAC2 PDCD1LG2

1.53e-041796741016af3d61a9276a792629f8b1a28a93038e29c1
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES ZNF683 C11orf16 RAC2

1.53e-04179674f7d3d37505893ae55065c89d957084602729decc
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.53e-04179674fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 TEP1

1.53e-041796746d2458a887047b5c20389f08345ff5aac7c683e6
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EOMES EFNA3 HLA-DRB1 ZNF683

1.56e-04180674f24d4cbba4cb50fce3b3d9c4629aa856d9b05358
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF683 CR1 CD300C RAC2

1.56e-041806741c5515f29ead129bee3b4ca27799796956811a39
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 IRF5 CR1 RAC2

1.59e-04181674e7d9910f6143055645b6f03b1018282e6c215f10
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES NAPSA ZNF683 RAC2

1.59e-04181674dd4126bf3c02e63866e2b3f2db81e3565f0e8c40
ToppCelldroplet-Lung-18m-Hematologic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA RNF149 IRF5 RAC2

1.59e-04181674f6017f64ff236a9a7d2c4810aa2f350b5f02f8ad
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

EFNA3 STRA6 RNF43 PDCD1LG2

1.59e-0418167433938e6521712058312879f84f4ae381c2bfc379
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

HLA-DRB1 IRF5 CD300C RAC2

1.59e-04181674193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCellwk_15-18-Hematologic-Myeloid-pre-pDC/DC5|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 IRF5 CD300C RAC2

1.63e-04182674748401d2c84260a777001dd75b0182453185addc
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA HLA-DRB1 CR1 RAC2

1.70e-04184674a068ae741889d59937690c11e0bf405481402c25
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 RAC2 PDCD1LG2

1.73e-04185674bf4dbb5f139566750e50a81eb062ed8b9e5786c3
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA IRF5 RAC2 PDCD1LG2

1.73e-041856743d035bb453a5942411da4eb8b3a1ca0961a089b2
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES NAPSA ZNF683 RAC2

1.77e-04186674e37e317e9770e35cb41137f51868d8b20ecd21d8
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAPSA HLA-DRB1 CR1 RAC2

1.77e-04186674b5e094850ac3785775393cd78a939b02339732b0
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; PC3; HT_HG-U133A

STK11 ANKFY1 PIDD1 PCNX1 HIC2 IRF5 STRA6

1.89e-061986774681_UP
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A

METTL25B ANKFY1 EFNA3 FRMPD1 ADCK2 PCNX1

2.50e-051976764189_DN
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A

EFNA3 PCNX1 HIC2 STRA6 MAP4K2 RAC2

2.50e-051976764831_UP
DrugDeltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A

EFNA3 PCNX1 IRF5 STRA6 CBL MAP4K2

2.50e-051976766026_DN
DrugCloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A

METTL25B ANKFY1 PIDD1 PMEL CBL RNF43

2.65e-051996762289_DN
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

STARD8 EFCAB6 FRMPD1 HRH4 ADCK2 CD300C

2.65e-051996763786_UP
DrugB258

RAC2 RAC3

1.27e-046672CID000593690
DrugDBMIB

JMJD6 ETFDH RAC2

1.91e-0438673CID000034474
DrugMonensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A

STK11 SPEG AMBRA1 ADCK2 TEP1

2.27e-041876757402_DN
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; HL60; HT_HG-U133A

ANKFY1 PIDD1 PCNX1 CR1 CBL

2.44e-041906751343_DN
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A

FZD8 ANKFY1 PCNX1 TEP1 CBL

2.50e-041916754298_DN
DrugClidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A

STK11 TTBK2 PCNX1 STRA6 TEP1

2.50e-041916756837_DN
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A

ADCK2 PCNX1 PMEL CR1 CBL

2.50e-041916752824_UP
DrugNimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A

STK11 FRMPD1 PCNX1 CR1 TEP1

2.62e-041936752275_UP
DrugPrilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A

ANKFY1 EFNA3 PCNX1 CBL RAC3

2.62e-041936753624_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

EFNA3 JMJD6 PCNX1 HIC2 CBL

2.62e-041936755602_DN
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A

STK11 TTBK2 PIDD1 PCNX1 TEP1

2.68e-041946756833_DN
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A

STARD8 ADCK2 PCNX1 IRF5 RAC3

2.68e-041946755954_UP
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A

SPEG PIDD1 AMBRA1 CR1 MAP4K2

2.75e-041956753393_DN
DrugAcacetin [480-44-4]; Up 200; 14uM; HL60; HT_HG-U133A

EFCAB6 JMJD6 PMEL CR1 RAC3

2.75e-041956752189_UP
DrugBromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A

STK11 ANKFY1 IRF5 CBL RNF43

2.75e-041956753719_DN
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A

EFNA3 JMJD6 AMBRA1 PCNX1 MAP4K2

2.75e-041956756648_DN
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

STK11 EFNA3 FRMPD1 HRH4 C11orf16

2.81e-041966753571_UP
DrugNizatidine [76963-41-2]; Up 200; 12uM; PC3; HT_HG-U133A

METTL25B FRMPD1 PIDD1 PCNX1 TEP1

2.81e-041966756305_UP
DrugRifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A

HIC2 PMEL STRA6 TEP1 CBL

2.81e-041966752847_UP
DrugSolasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

METTL25B EFNA3 PIDD1 HIC2 TEP1

2.81e-041966753830_DN
DrugMethacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

PIDD1 PCNX1 HIC2 CBL RAC3

2.81e-041966754143_DN
DrugTheobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A

STK11 FRMPD1 PIDD1 PCNX1 TEP1

2.81e-041966754958_UP
DrugDinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

METTL25B PIDD1 HIC2 MAP4K2 RAC3

2.81e-041966755409_DN
DrugCephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A

ANKFY1 EFNA3 AMBRA1 ADCK2 IRF5

2.81e-041966752628_DN
DrugKaempferol [520-18-3]; Up 200; 14uM; MCF7; HT_HG-U133A

STK11 EFNA3 JMJD6 HIC2 C11orf16

2.81e-041966753579_UP
DrugCefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A

STK11 ANKFY1 AMBRA1 IRF5 RAC3

2.81e-041966756323_DN
DrugCalycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A

STK11 METTL25B ANKFY1 EFNA3 ADCK2

2.81e-041966752764_DN
Drug1-phenylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A

METTL25B STARD8 KLF15 AMBRA1 PCNX1

2.88e-0419767522_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

EFNA3 PCNX1 HIC2 MAP4K2 RAC3

2.88e-041976756060_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

TTBK2 PIDD1 HIC2 IRF5 TEP1

2.88e-041976756940_UP
DrugFlutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A

TTBK2 ADCK2 HIC2 PMEL RAC3

2.88e-041976753885_DN
Drug(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A

TTBK2 EFNA3 ADCK2 PCNX1 HIC2

2.88e-041976755999_DN
DrugPractolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A

FRMPD1 PIDD1 ADCK2 CR1 CBL

2.88e-041976755664_UP
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

FZD8 ANKFY1 EFNA3 SPEG PCNX1

2.88e-041976756758_DN
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A

PCNX1 IRF5 TEP1 RNF43 MAP4K2

2.88e-041976753877_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

STK11 EFNA3 ADCK2 PCNX1 TEP1

2.88e-041976754730_DN
DrugIsoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A

METTL25B AMBRA1 PCNX1 C11orf16 CR1

2.88e-041976755840_UP
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A

EFNA3 PCNX1 STRA6 CBL MAP4K2

2.95e-041986756053_DN
DrugDilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A

JMJD6 PIDD1 PCNX1 HIC2 CD300C

2.95e-041986752294_UP
DrugPentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A

ANKFY1 EFNA3 JMJD6 ADCK2 HIC2

2.95e-041986757375_UP
DrugPipemidic acid [51940-44-4]; Up 200; 13.2uM; HL60; HT_HG-U133A

FZD8 EFNA3 ADCK2 PCNX1 CBL

2.95e-041986753093_UP
Drug3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A

PIDD1 PCNX1 IRF5 TEP1 RNF43

2.95e-041986755259_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A

STK11 METTL25B JMJD6 AMBRA1 RAC3

2.95e-041986753112_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A

TTBK2 METTL25B SPEG AMBRA1 MAP4K2

2.95e-041986752047_DN
DrugCephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A

STK11 EFCAB6 SPEG HIC2 CBL

2.95e-041986755615_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A

CR1 CBL RNF43 RAC2 RAC3

2.95e-041986755214_UP
DrugBisoprolol fumarate; Down 200; 9uM; HL60; HT_HG-U133A

TTBK2 PIDD1 AMBRA1 PCNX1 HIC2

2.95e-041986751287_DN
DrugNitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ANKFY1 EFNA3 PCNX1 STRA6 CBL

2.95e-041986756043_DN
Drugondansetron

JMJD6 HRH4 RNF43

2.96e-0444673CID000004595
DrugMefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A

STK11 ANKFY1 PIDD1 ADCK2 RAC3

3.02e-041996751863_UP
DrugBufexamac [2438-72-4]; Up 200; 18uM; PC3; HT_HG-U133A

FRMPD1 PIDD1 HIC2 CR1 RNF43

3.02e-041996755090_UP
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A

EFNA3 PIDD1 PCNX1 TEP1 CBL

3.02e-041996757429_UP
DrugThalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A

PIDD1 AMBRA1 PCNX1 PMEL CR1

3.02e-041996752095_UP
DrugLevamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A

STARD8 PIDD1 PCNX1 TEP1 RAC2

3.02e-041996757450_UP
Drugbenserazide hydrochloride; Up 200; 10uM; MCF7; HG-U133A

STARD8 KLF15 ADCK2 IRF5 RAC2

3.02e-04199675641_UP
DrugKetorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PIDD1 AMBRA1 ADCK2 RNF43 RAC3

3.02e-041996755988_DN
DrugFlecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

STARD8 SPEG PMEL CBL RNF43

3.09e-042006753418_UP
DrugNoscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A

TTBK2 ANKFY1 SPEG PIDD1 RNF43

3.09e-042006757204_UP
Diseaseautosomal dominant intellectual developmental disorder 48 (implicated_via_orthology)

RAC2 RAC3

1.43e-053652DOID:0080235 (implicated_via_orthology)
DiseaseDiffuse Scleroderma

HLA-DRB1 IRF5

4.76e-055652C1258104
DiseaseCREST Syndrome

HLA-DRB1 IRF5

7.13e-056652C0206138
DiseaseScleroderma, Limited

HLA-DRB1 IRF5

7.13e-056652C0748540
Diseaseestrogen measurement

SLC22A9 SLC22A10

2.13e-0410652EFO_0011007
Diseaseovarian neoplasm

STK11 JMJD6 SLC22A10 RNF43

2.22e-04134654C0919267
DiseaseMalignant neoplasm of ovary

STK11 JMJD6 SLC22A10 RNF43

2.42e-04137654C1140680
DiseaseBenign tumor of pancreas

STK11 RNF43

3.67e-0413652C0347284
Diseaserheumatoid arthritis, COVID-19

EFNA3 HLA-DRB1 IRF5

3.86e-0464653EFO_0000685, MONDO_0100096
Diseaseemployment status

PLXNA4 KLF15

4.93e-0415652EFO_0005241
DiseasePancreatic carcinoma

STK11 RNF43

7.98e-0419652C0235974
DiseaseJuvenile Myelomonocytic Leukemia

CBL RAC2

7.98e-0419652C0349639
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

TEP1 RNF43

7.98e-0419652DOID:4928 (is_marker_for)
Diseasealcohol use disorder (implicated_via_orthology)

ZNF683 MAP4K2 RAC2 RAC3

9.14e-04195654DOID:1574 (implicated_via_orthology)
Diseasefetal hemoglobin measurement

OR51B6 PRDM5

9.77e-0421652EFO_0004576
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

ETFDH MAP4K2

1.39e-0325652EFO_0004465, EFO_0004466, EFO_0004469
Diseasecolorectal adenocarcinoma (is_marker_for)

RICTOR STRA6

1.62e-0327652DOID:0050861 (is_marker_for)
DiseaseQRS-T angle

ADAMTSL1 SPEG PCNX1

1.67e-03106653EFO_0020097
DiseaseNeoplasm of uncertain or unknown behavior of ovary

STK11 RNF43

1.87e-0329652C0496920
Diseasemultiple sclerosis

EOMES ADAMTSL1 CSGALNACT2 HLA-DRB1 SPRY4 IRF5

1.96e-03594656MONDO_0005301
DiseaseOvarian Carcinoma

STK11 RNF43

2.00e-0330652C0029925

Protein segments in the cluster

PeptideGeneStartEntry
LCNRPLWLKFHRHQT

EOMES

271

O95936
QFSKLHVRVTPHPWT

ADCK2

166

Q7Z695
PHPWTHTERFLRQAF

ADCK2

176

Q7Z695
HVQKLPWDHVPCLRR

C1orf167

91

Q5SNV9
LIGHRRTPWCVTFHP

AMBRA1

91

Q9C0C7
KHPTHWNRQCTFILR

CC2D2B

1331

Q6DHV5
EKEHRTLNKFWCRPP

CD300C

46

Q08708
RTHPTWLLHIFIPFC

PDCD1LG2

216

Q9BQ51
ENVRAKWFPEVRHHC

RAC2

91

P15153
KWFPEVRHHCPSTPI

RAC2

96

P15153
KWYPEVRHHCPHTPI

RAC3

96

P60763
PRHSNWLRFVHEAPS

PRDM5

76

Q9NQX1
CPLRIHAAVTWIHPV

MAP4K2

481

Q12851
HRNKWGETPLHTACR

ANKFY1

486

Q9P2R3
QGHKRWCLFPTSTPR

JMJD6

201

Q6NYC1
PIIHRWRETDFFPCS

ADAMTSL1

296

Q8N6G6
LPQVRKQLPWHCFSH

PCNX1

1311

Q96RV3
TATFHRCAKDPWRLP

PCSK9

61

Q8NBP7
DPHVRHTWKSNCLPL

PLXNA4

1731

Q9HCM2
PIVVRLHWFPYCRSH

OR51B6

156

Q9H340
SVLFPIWFKCHRPRH

MRGPRD

126

Q8TDS7
SPHHVVRWVDPTALC

METTL25B

221

Q96FB5
KLFCIPWRHATRHGP

IRF5

41

Q13568
SCPANLASHRRWHKP

INSM2

301

Q96T92
DAVRHSRKHLWPVVP

RICTOR

991

Q6R327
HNRPRWEATHNCPCL

FZD8

556

Q9H461
PFREFQRWKHHPSIR

ETFDH

336

Q16134
QRWKHHPSIRPTLEG

ETFDH

341

Q16134
TPVPGLFHLWHEKRC

CSGALNACT2

476

Q8N6G5
WKHRSLSPVPRNAEH

BCLAF3

11

A2AJT9
KRWECNRPHAPHSPI

EFNA3

106

P52797
DRWDPPLAKCTSRTH

CR1

1956

P17927
IIPDWLRSHPHTRKF

EFCAB6

6

Q5THR3
HPPEKCTWHFTESRS

FRMPD1

1446

Q5SYB0
DTRPRFLWQPKRECH

HLA-DRB1

31

P01911
THLPKTRPRLWHTAC

KLHDC1

291

Q8N7A1
HLRRHTGEKPFACTW

KLF15

341

Q9UIH9
PWKSFRQALHEVHPI

CBL

201

P22681
RHCRHFPLLWDAPAK

B3GNT6

96

Q6ZMB0
QQARHLRWAHPPSKA

PKD1L1

2251

Q8TDX9
EAPQRLWAHCQVPHF

PIDD1

431

Q9HB75
HPCSNSIFRWREKEH

NOSTRIN

381

Q8IVI9
RDWNRLKNHPSLRCH

FAN1

636

Q9Y2M0
RQHEKTHWLTRPFPC

HIC2

521

Q96JB3
LWKRDHLSRCQSHPG

HRH4

201

Q9H3N8
EALHPRKERWHIFPS

RGMB

396

Q6NW40
PTPARCDQDVTHHWI

SPRY4

76

Q9C004
HLWRDRVCQLCHPSP

LTB4R2

161

Q9NPC1
EKCRRFVHPQWQLLH

SLC22A9

86

Q8IVM8
EKCRRFVHPQWQLLH

SLC22A10

86

Q63ZE4
RSIHVPHAVWPFQVK

PRDM7

416

Q9NQW5
RNCVDPWLHQHRTCP

RNF43

296

Q68DV7
RNAPVSRPHSWHVAK

SHROOM4

91

Q9ULL8
RQIRQHSWFRKKHPP

STK11

301

Q15831
PHSSSHWLRLPRIFC

PMEL

631

P40967
CRKLRWHSFQNSHRP

STARD8

491

Q92502
LHRSPHPSRQAIFCW

STRA6

406

Q9BX79
HKSFTREHPRPLHWA

C11orf16

226

Q9NQ32
PQHSSHWCPEREKVK

C11orf40

26

Q8WZ69
PCKHIFHRICIDPWL

RNF149

286

Q8NC42
PVLIHSFPACHRDWV

TEP1

2096

Q99973
VHPWSRPSLQDCLAH

SPEG

3201

Q15772
WRVHQPGCKPLSTFR

MEX3A

321

A1L020
SHIPLRPKHWFQLCR

SPDYE3

476

A6NKU9
HKPCVPAVSRTDHIW

TTBK2

491

Q6IQ55
PHWKRHQLTHFKERP

ZNF770

666

Q6IQ21
HQRIHSTERPFKCQW

ZNF445

886

P59923
WARHHPQVPDVSCLV

WSB2

111

Q9NYS7
VHTGERPHKCSIPWV

ZNF683

371

Q8IZ20
PRAWECHLRRVHNLT

nan

41

Q6ZRX8
FFSVPCWLHHRFDPK

NAPSA

111

O96009