Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

6.86e-06120214GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

5.11e-05200214GO:0008237
GeneOntologyMolecularFunctionNotch binding

JAG2 NOTCH1

3.64e-0427212GO:0005112
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

9.49e-04430214GO:0004175
GeneOntologyMolecularFunctiontranscription coactivator activity

KMT2C WDR77 NOTCH1

3.76e-03303213GO:0003713
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

4.38e-03654214GO:0008233
GeneOntologyBiologicalProcesssecretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

WDR77 NOTCH1

5.35e-064202GO:0060528
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 NOTCH1

1.34e-056202GO:0060120
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 NOTCH1

1.34e-056202GO:0009912
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS12 ADAMTS14 ADAMTS9 NOTCH1 ADAMTSL2

2.46e-05377205GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS12 ADAMTS14 ADAMTS9 NOTCH1 ADAMTSL2

2.49e-05378205GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS12 ADAMTS14 ADAMTS9 NOTCH1 ADAMTSL2

2.52e-05379205GO:0045229
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation involved in prostate gland development

WDR77 NOTCH1

4.89e-0511202GO:0060768
GeneOntologyBiologicalProcessprostate glandular acinus development

WDR77 NOTCH1

5.86e-0512202GO:0060525
GeneOntologyBiologicalProcessepithelial cell proliferation involved in prostate gland development

WDR77 NOTCH1

5.86e-0512202GO:0060767
GeneOntologyBiologicalProcessepithelial cell differentiation involved in prostate gland development

WDR77 NOTCH1

9.31e-0515202GO:0060742
GeneOntologyBiologicalProcessanatomical structure maturation

ADAMTS12 SCARF1 WDR77 NOTCH1

3.32e-04354204GO:0071695
GeneOntologyBiologicalProcessapoptotic process involved in morphogenesis

JAG2 NOTCH1

4.35e-0432202GO:0060561
GeneOntologyBiologicalProcesscell-substrate adhesion

ADAMTS12 ADAMTS9 TMEM8B NOTCH1

5.79e-04410204GO:0031589
GeneOntologyBiologicalProcessaorta morphogenesis

ADAMTS9 NOTCH1

7.16e-0441202GO:0035909
GeneOntologyBiologicalProcessdevelopmental maturation

ADAMTS12 SCARF1 WDR77 NOTCH1

7.48e-04439204GO:0021700
GeneOntologyBiologicalProcessapoptotic process involved in development

JAG2 NOTCH1

9.41e-0447202GO:1902742
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

JAG2 NOTCH1

1.19e-0353202GO:0045747
GeneOntologyBiologicalProcessbiological phase

SYCP2 NOTCH1

1.19e-0353202GO:0044848
GeneOntologyCellularComponentextracellular matrix

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2 ANGPTL4

4.53e-05656226GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2 ANGPTL4

4.61e-05658226GO:0030312
DomainTSP_1

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

7.25e-0963215PF00090
DomainTSP1

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

8.51e-0965215SM00209
DomainTSP1_rpt

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

8.51e-0965215IPR000884
DomainTSP1

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

8.51e-0965215PS50092
DomainADAM_spacer1

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

1.03e-0823214IPR010294
DomainADAM_spacer1

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

1.03e-0823214PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

1.24e-0824214IPR013273
DomainEGF_3

SCARF1 JAG2 SSPOP PGAP6 TMEM8B NOTCH1

1.72e-07235216PS50026
DomainEGF_1

SCARF1 JAG2 SSPOP PGAP6 TMEM8B NOTCH1

2.79e-07255216PS00022
DomainEGF_2

SCARF1 JAG2 SSPOP PGAP6 TMEM8B NOTCH1

3.50e-07265216PS01186
DomainPLAC

ADAMTS12 ADAMTS14 ADAMTSL2

1.17e-0619213IPR010909
DomainPLAC

ADAMTS12 ADAMTS14 ADAMTSL2

1.17e-0619213PS50900
DomainDUF3522

PGAP6 TMEM8B

3.61e-063212PF12036
DomainDUF3522

PGAP6 TMEM8B

3.61e-063212IPR021910
DomainEGF

SCARF1 JAG2 PGAP6 TMEM8B NOTCH1

5.22e-06235215SM00181
DomainEGF-like_CS

SCARF1 JAG2 PGAP6 TMEM8B NOTCH1

8.69e-06261215IPR013032
DomainPeptidase_M12B_N

ADAMTS12 ADAMTS14 ADAMTS9

1.09e-0539213IPR002870
DomainPep_M12B_propep

ADAMTS12 ADAMTS14 ADAMTS9

1.09e-0539213PF01562
DomainDISINTEGRIN_1

ADAMTS12 ADAMTS14 ADAMTS9

1.18e-0540213PS00427
DomainADAM_MEPRO

ADAMTS12 ADAMTS14 ADAMTS9

1.18e-0540213PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAMTS14 ADAMTS9

1.18e-0540213PS50214
DomainReprolysin

ADAMTS12 ADAMTS14 ADAMTS9

1.18e-0540213PF01421
DomainPeptidase_M12B

ADAMTS12 ADAMTS14 ADAMTS9

1.18e-0540213IPR001590
DomainCYSTEINE_SWITCH

ADAMTS12 ADAMTS14 ADAMTS9

1.27e-0541213PS00546
DomainDisintegrin_dom

ADAMTS12 ADAMTS14 ADAMTS9

1.27e-0541213IPR001762
DomainPept_M10_metallopeptidase

ADAMTS12 ADAMTS14 ADAMTS9

1.47e-0543213IPR001818
DomainEGF_extracell

SCARF1 JAG2 NOTCH1

4.02e-0560213IPR013111
DomainEGF_2

SCARF1 JAG2 NOTCH1

4.02e-0560213PF07974
DomainMetalloPept_cat_dom

ADAMTS12 ADAMTS14 ADAMTS9

9.88e-0581213IPR024079
Domain-

ADAMTS12 ADAMTS14 ADAMTS9

9.88e-05812133.40.390.10
DomainEGF-like_dom

SCARF1 JAG2 PGAP6 NOTCH1

1.54e-04249214IPR000742
DomainZINC_PROTEASE

ADAMTS12 ADAMTS14 ADAMTS9

1.74e-0498213PS00142
DomainVWC_out

JAG2 SSPOP

2.04e-0419212SM00215
DomainhEGF

JAG2 NOTCH1

4.47e-0428212PF12661
DomainGrowth_fac_rcpt_

SCARF1 JAG2 NOTCH1

6.81e-04156213IPR009030
DomainVWFC_1

JAG2 SSPOP

7.41e-0436212PS01208
DomainVWC

JAG2 SSPOP

8.26e-0438212SM00214
DomainVWFC_2

JAG2 SSPOP

8.26e-0438212PS50184
DomainVWF_dom

JAG2 SSPOP

1.01e-0342212IPR001007
DomainEGF_CA

JAG2 NOTCH1

4.16e-0386212PF07645
DomainEGF_Ca-bd_CS

JAG2 NOTCH1

5.26e-0397212IPR018097
DomainEGF_CA

JAG2 NOTCH1

5.47e-0399212PS01187
DomainASX_HYDROXYL

JAG2 NOTCH1

5.58e-03100212PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 NOTCH1

6.25e-03106212IPR000152
DomainEGF_CA

JAG2 NOTCH1

8.19e-03122212SM00179
DomainEGF-like_Ca-bd_dom

JAG2 NOTCH1

8.45e-03124212IPR001881
DomainEGF

JAG2 NOTCH1

8.72e-03126212PF00008
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP NOTCH1 ADAMTSL2

1.78e-1068186M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

1.04e-0939185M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

1.04e-0939185MM15165
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP NOTCH1 ADAMTSL2

1.65e-08143186M27275
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

1.99e-07109185MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

2.18e-07111185M27416
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP NOTCH1 ADAMTSL2

4.55e-07250186M27554
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 NOTCH1

3.22e-057182M27199
PathwayPID_NOTCH_PATHWAY

JAG2 SSPOP NOTCH1

5.43e-0559183M17
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

6.89e-0510182MM14849
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

1.19e-0413182M47423
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1

1.60e-0415182M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

1.83e-0416182M47424
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 NOTCH1

2.07e-0417182M39389
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

2.33e-0418182MM14775
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH1

5.30e-0427182M39545
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

7.01e-0431182M592
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 NOTCH1

1.11e-0339182MM14604
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH1

1.48e-0345182M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

1.54e-0346182MM15971
PathwayPID_PS1_PATHWAY

SSPOP NOTCH1

1.54e-0346182M70
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

1.61e-0347182M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 NOTCH1

1.75e-0349182M618
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1

2.44e-0358182M29616
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 NOTCH1

2.70e-0361182M39540
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

KMT2C NOTCH1

3.05e-0365182M39682
PathwayPID_HDAC_CLASSI_PATHWAY

SSPOP WDR77

3.15e-0366182M101
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

3.94e-0374182M616
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

4.81e-0382182MM15922
PathwayWP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS

NOTCH1 TG

6.15e-0393182M39791
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS12 ADAMTS14 ADAMTS9 SSPOP ADAMTSL2

1.33e-097523520637190
Pubmed

Downregulation of Notch-1/Jagged-2 in human colon tissues from Hirschsprung disease patients.

JAG2 NOTCH1

4.18e-07223221892607
Pubmed

Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.

JAG2 NOTCH1

4.18e-07223211700865
Pubmed

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.

JAG2 NOTCH1

4.18e-07223223074278
Pubmed

[Expression and significance of Notch-1 and Jagged-2 in patients with Hirschsprung disease].

JAG2 NOTCH1

4.18e-07223222030773
Pubmed

Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse.

JAG2 NOTCH1

1.25e-06323219181188
Pubmed

ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.

JAG2 NOTCH1

1.25e-06323238485033
Pubmed

The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.

JAG2 NOTCH1

1.25e-06323237330998
Pubmed

Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.

JAG2 NOTCH1

1.25e-06323218458347
Pubmed

A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.

JAG2 NOTCH1

2.51e-06423210837254
Pubmed

Notch signalling pathway mediates hair cell development in mammalian cochlea.

JAG2 NOTCH1

2.51e-06423210080181
Pubmed

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

JAG2 NOTCH1

2.51e-0642329315665
Pubmed

Activation of Notch signaling in human tongue carcinoma.

JAG2 NOTCH1

2.51e-06423220819128
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

JAG2 NOTCH1

2.51e-06423220040020
Pubmed

The Notch signalling pathway in hair growth.

JAG2 NOTCH1

2.51e-0642329858728
Pubmed

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.

JAG2 NOTCH1

2.51e-06423224398584
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG2 NOTCH1

4.18e-06523211006133
Pubmed

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.

JAG2 NOTCH1

4.18e-06523212175503
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 NOTCH1

4.18e-06523215064243
Pubmed

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.

JAG2 NOTCH1

4.18e-06523232255245
Pubmed

Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform.

JAG2 NOTCH1

4.18e-06523217332426
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 NOTCH1

6.26e-06623210958687
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 NOTCH1

8.77e-06723210383933
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH1

8.77e-06723210079256
Pubmed

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice.

JAG2 NOTCH1

8.77e-0672329531541
Pubmed

Evidence for a Notch1-mediated transition during olfactory ensheathing cell development.

JAG2 NOTCH1

8.77e-06723227271278
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

JAG2 NOTCH1

8.77e-06723216169548
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH1

8.77e-06723212846471
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 NOTCH1

1.17e-05823222652674
Pubmed

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

JAG2 NOTCH1

1.17e-05823216141228
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH1

1.17e-0582329858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 NOTCH1

1.17e-05823211044610
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH1

1.50e-05923211118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH1

1.50e-05923216245338
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

JAG2 NOTCH1

1.50e-05923211944948
Pubmed

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.

ADAMTS9 NOTCH1

1.50e-05923223095891
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

JAG2 NOTCH1

1.50e-05923210837027
Pubmed

Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence.

JAG2 NOTCH1

1.88e-051023219439425
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH1

1.88e-051023223665443
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS12 ADAMTS9

1.88e-051023211167130
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH1

2.29e-051123216607638
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH1

2.29e-051123210878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH1

2.29e-051123212866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH1

2.75e-051223215465494
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS12 ADAMTS9

2.75e-051223225770910
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 NOTCH1

3.25e-051323231202705
Pubmed

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.

JAG2 NOTCH1

3.25e-051323234838591
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH1

3.25e-051323211578869
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG2 NOTCH1

3.79e-051423228192800
Pubmed

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

JAG2 NOTCH1

3.79e-051423218528438
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH1

3.79e-051423214757642
Pubmed

Notch1 is required for neuronal and glial differentiation in the cerebellum.

JAG2 NOTCH1

3.79e-051423211807030
Pubmed

BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling.

JAG2 NOTCH1

4.37e-051523216324690
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH1

4.37e-051523212971992
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

JAG2 NOTCH1

4.37e-05152329291577
Pubmed

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

JAG2 NOTCH1

4.37e-051523217194759
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 NOTCH1

4.37e-051523212167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 NOTCH1

4.37e-051523216914494
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG2 NOTCH1

4.99e-051623227641601
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 NOTCH1

4.99e-051623212617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 NOTCH1

4.99e-051623210842072
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 NOTCH1

4.99e-051623232161758
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 NOTCH1

4.99e-051623217273555
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 NOTCH1

5.66e-051723218694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 NOTCH1

5.66e-051723215821257
Pubmed

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution.

JAG2 NOTCH1

6.36e-051823236899896
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 NOTCH1

6.36e-051823218093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 NOTCH1

6.36e-051823215689374
Pubmed

Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.

JAG2 NOTCH1

7.10e-051923218505817
Pubmed

Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development.

JAG2 NOTCH1

7.10e-051923221302255
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 NOTCH1

7.10e-051923216518823
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

JAG2 NOTCH1

7.89e-052023229961574
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 NOTCH1

8.72e-052123228656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH1

8.72e-052123214702043
Pubmed

Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.

JAG2 NOTCH1

8.72e-052123231631837
Pubmed

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

JAG2 NOTCH1

8.72e-052123219686682
Pubmed

FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development.

JAG2 NOTCH1

8.72e-052123214651921
Pubmed

The role of Irf6 in tooth epithelial invagination.

JAG2 NOTCH1

9.59e-052223222366192
Pubmed

Sequential Notch activation regulates ventricular chamber development.

JAG2 NOTCH1

9.59e-052223226641715
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 NOTCH1

9.59e-052223221750033
Pubmed

Notch signalling regulates epibranchial placode patterning and segregation.

JAG2 NOTCH1

1.05e-042323231988190
Pubmed

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.

JAG2 NOTCH1

1.05e-042323224337118
Pubmed

PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.

JAG2 NOTCH1

1.05e-042323231504280
Pubmed

Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.

JAG2 NOTCH1

1.05e-042323223386589
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 NOTCH1

1.05e-042323214701881
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

JAG2 NOTCH1

1.14e-042423221420948
Pubmed

WD40 repeat and FYVE domain containing 3 is essential for cardiac development.

JAG2 NOTCH1

1.24e-042523230428088
Pubmed

Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin.

JAG2 NOTCH1

1.24e-042523230220568
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 NOTCH1

1.35e-042623219369401
Pubmed

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

ADAMTS9 NOTCH1

1.45e-042723220490451
Pubmed

A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice.

JAG2 NOTCH1

1.45e-042723229956664
Pubmed

Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

JAG2 NOTCH1

1.45e-042723224148613
Pubmed

Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate.

JAG2 NOTCH1

1.56e-042823219782673
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 NOTCH1

1.68e-042923225535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

JAG2 NOTCH1

1.68e-042923221402740
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

JAG2 NOTCH1

1.80e-043023224552588
Pubmed

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.

JAG2 NOTCH1

1.80e-043023216524929
Pubmed

pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.

JAG2 NOTCH1

1.80e-043023217257418
Pubmed

ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.

JAG2 NOTCH1

1.92e-043123237573008
Pubmed

Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.

JAG2 NOTCH1

2.18e-043323216000382
Cytoband7q36.1

KMT2C SSPOP

7.51e-04742527q36.1
CytobandEnsembl 112 genes in cytogenetic band chr7q36

KMT2C SSPOP

3.39e-03159252chr7q36
CytobandEnsembl 112 genes in cytogenetic band chr19p13

THSD8 DNASE2 ANGPTL4

9.02e-03797253chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr9q34

NOTCH1 ADAMTSL2

1.35e-02325252chr9q34
CytobandEnsembl 112 genes in cytogenetic band chr17p13

SCARF1 C17orf114

1.52e-02346252chr17p13
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS14 ADAMTS9

2.80e-071913350
CoexpressionCUI_DEVELOPING_HEART_C4_ENDOTHELIAL_CELL

SCARF1 ADAMTS9 NOTCH1 ANGPTL4

9.00e-06146244M39301
CoexpressionNABA_MATRISOME

ADAMTS12 CLEC6A ADAMTS14 ADAMTS9 SSPOP ADAMTSL2 ANGPTL4

2.37e-051008247MM17056
CoexpressionNABA_MATRISOME

ADAMTS12 CLEC6A ADAMTS14 ADAMTS9 SSPOP ADAMTSL2 ANGPTL4

2.66e-051026247M5889
CoexpressionGSE3982_MAST_CELL_VS_BASOPHIL_UP

ATP13A3 TMEM8B WDR77 TG

2.92e-05197244M5438
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS12 CLEC6A ADAMTS14 ADAMTS9 ADAMTSL2 ANGPTL4

4.26e-05738246MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS12 CLEC6A ADAMTS14 ADAMTS9 ADAMTSL2 ANGPTL4

4.69e-05751246M5885
CoexpressionNABA_ECM_REGULATORS

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

6.11e-05238244M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS12 ADAMTS14 ADAMTS9 ADAMTSL2

6.51e-05242244MM17062
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1

9.57e-0516242M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1

9.57e-0516242MM1296
CoexpressionLU_TUMOR_ANGIOGENESIS_UP

JAG2 NOTCH1

2.38e-0425242M9946
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYCP2 ATP13A3 ADAMTS9 NOTCH1

3.34e-061862544ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.64e-06190254bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.64e-06190254d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.64e-0619025438a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.79e-061922540986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.79e-06192254b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9 NOTCH1

3.79e-061922548f20d3511dcb44445592b17d005a53da0052ae56
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP13A3 ADAMTS14 ADAMTS9 ANGPTL4

4.11e-06196254b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9 NOTCH1

4.37e-06199254b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9 NOTCH1

4.37e-06199254f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCelldroplet-Heart-nan-18m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 NOTCH1 SPHKAP

4.72e-05126253de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 CLEC6A SSPOP

6.18e-05138253c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 CLEC6A SSPOP

6.73e-0514225367d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

SCARF1 JAG2 NOTCH1

9.76e-0516125352239a887799362256ecd7e740b716b88ed59a62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 DNASE2 ADAMTSL2

9.94e-05162253bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

CLEC6A ADAMTSL2 ANGPTL4

1.07e-041662537c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

CLEC6A ADAMTSL2 ANGPTL4

1.07e-041662537286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCelldroplet-Fat-Scat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC6A PGAP6 DNASE2

1.11e-04168253749eccebe4ee066f827d2a3980512f195f23ac27
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

JAG2 SYCP2 WDR77

1.17e-04171253b113fbebb89056af0b9c775d2fb6552206a80467
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAG2 ADAMTS9 NOTCH1

1.19e-04172253c84cab89c97d647b8a256fd08e33d9102810febd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS9 NOTCH1 ANGPTL4

1.27e-041762532bc4d3ddc2f752d8255dec0e7a9b87c7f82a372d
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS12 SPHKAP ADAMTSL2

1.34e-0417925310fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.36e-04180253755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ADAMTS9 NOTCH1

1.40e-041822530346f81bbb1f309f3e9d063b20547d548d09472c
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.47e-04185253dec60254204014083ff3b4aec0cc75410950a486
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

ADAMTS14 ADAMTS9 ADAMTSL2

1.47e-041852534905adaeeffd353e089578e5ea614437dbe794e6
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A3 CLEC6A DNASE2

1.47e-04185253afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A3 CLEC6A DNASE2

1.47e-04185253775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.47e-04185253201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.47e-04185253334f006c3ef33338ff8d649309d3f448733a3a99
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.47e-04185253a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAG2 SYCP2 ADAMTS9

1.50e-04186253a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCARF1 ADAMTS9 ADAMTSL2

1.52e-04187253be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ADAMTS9 NOTCH1

1.52e-0418725325efb82afe863a853ecdd781ad89026c993aaa67
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JAG2 ATP13A3 NOTCH1

1.54e-04188253366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ADAMTS9 ADAMTSL2

1.54e-04188253a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.54e-0418825320072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 SSPOP NOTCH1

1.54e-04188253524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCellfacs-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.54e-04188253dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 SSPOP NOTCH1

1.54e-04188253d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.54e-041882536ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ADAMTS9 NOTCH1

1.57e-04189253db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-041892535559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.57e-04189253e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 ADAMTS9 NOTCH1

1.57e-041892533fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1

1.59e-04190253632d5dc11765053366d61f0a0c7916111cea4f50
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTS9 NOTCH1

1.59e-041902532655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.59e-04190253141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9

1.62e-0419125390f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9

1.62e-04191253a0018f88f7132477cc467ee15db029a585290595
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 ADAMTS9

1.62e-041912536b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1

1.62e-041912531b1e943709d0c3283a980c7c965ef1f110506a29
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1

1.62e-0419125379b399496bd7322a1d53c43378f48695fd09a5d9
ToppCellfacs-Trachea-24m-Endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1

1.62e-041912539c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.64e-041922530f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.64e-041922531f35efb0765e05f7f9c881849953bef3965be25a
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.64e-04192253777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.64e-041922535a0615fdc217554ccd611504b16e5d97628e207d
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.64e-0419225360a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JAG2 ATP13A3 ANGPTL4

1.64e-04192253aedddccacf60e884af044cefba6c64ca10ac97d2
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JAG2 ATP13A3 ANGPTL4

1.64e-04192253389d5e6d0689371bfe1d0b06e92e0e6e5573567b
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1

1.64e-041922535012cc3ec0766f06af447463413422b484446c43
ToppCell(4)_Endothelial_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SCARF1 NOTCH1 ANGPTL4

1.67e-04193253ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCellfacs-MAT-Fat-24m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.67e-04193253ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KMT2C ATP13A3 TG

1.67e-04193253779276e775cb2492e8dd36436295a536084a6415
ToppCellfacs-MAT-Fat-24m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.67e-04193253737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCellfacs-MAT-Fat-24m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1

1.67e-04193253724bb613fa434add5b1c5586b629328f819fbdfe
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS12 ADAMTSL2 ANGPTL4

1.67e-04193253b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SCARF1 NOTCH1 ANGPTL4

1.69e-041942534428b472c2042f88eae028b1770767512a515b75
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 ATP13A3

1.72e-04195253a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ATP13A3 ADAMTS9

1.72e-04195253b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Early_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 ANGPTL4

1.74e-041962530f00aac6dac699507ce336020b2e96fd192de0be
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.74e-041962539b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 ADAMTS9 NOTCH1

1.74e-04196253ae46d4b00be92e64e46252dcc156161b171eded4
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 ADAMTSL2 ANGPTL4

1.74e-04196253cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 ADAMTSL2 ANGPTL4

1.74e-041962539737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 ATP13A3 ANGPTL4

1.74e-04196253cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.77e-0419725398e34e8612f111bb667a574de1faaa785d318ca4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 JAG2 ADAMTSL2

1.77e-041972539244f087ba4b60fdc81d54ce91860de715b3e12c
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.77e-04197253dfc052a447c3b32235fcaffdf06c4e0941723d19
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.80e-041982534a70a1ab40fe30b90acd97e4e36067db62acc905
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.80e-0419825309e452742aed9f48bf1ffc35c6b06a296bcfe076
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.80e-04198253ff8a9adc1302a4679ccdfe9ef95ef53e4c7a5391
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAG2 ADAMTS9 ANGPTL4

1.80e-041982531e83bec16dcd60460422625f89952ff506d6be51
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAG2 ADAMTS9 ANGPTL4

1.80e-041982532630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.80e-04198253f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 JAG2 ADAMTSL2

1.80e-0419825372e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.80e-04198253e9e98c20ff7b3f3851db86381550ce7085e2db9e
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS9 ANGPTL4 FAM87A

1.80e-04198253447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 JAG2 ADAMTSL2

1.82e-04199253d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP13A3 CLEC6A ANGPTL4

1.82e-04199253880ba91ccecc6633f6daba7822d9200548a8632f
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 ADAMTS9

1.82e-041992530d63da0afa93741c37609d879941de202d9ac86c
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JAG2 ADAMTS9 ANGPTL4

1.82e-041992531c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 JAG2 ADAMTSL2

1.82e-04199253cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
Diseasescoliosis (implicated_via_orthology)

ADAMTS9 SSPOP

6.33e-065242DOID:0060249 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

KMT2C DNASE2

4.16e-0512242DOID:7148 (implicated_via_orthology)
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH1

1.73e-0424242C0887833
DiseaseHeart valve disease

NOTCH1 ADAMTSL2

2.04e-0426242C0018824
DiseaseGlioblastoma

JAG2 NOTCH1

1.88e-0379242C0017636
DiseaseGiant Cell Glioblastoma

JAG2 NOTCH1

2.12e-0384242C0334588
Diseasecarpal tunnel syndrome

ADAMTS14 ADAMTSL2

2.38e-0389242EFO_0004143
DiseaseSquamous cell carcinoma of esophagus

KMT2C NOTCH1

2.70e-0395242C0279626
DiseaseAdenoid Cystic Carcinoma

KMT2C NOTCH1

2.99e-03100242C0010606
Diseaseblood cobalt measurement

ADAMTS14 POM121L12

3.05e-03101242EFO_0007577
DiseaseGlioblastoma Multiforme

JAG2 NOTCH1

3.67e-03111242C1621958
Diseasecortical surface area measurement

JAG2 IFT22 ADAMTS9 TMEM8B TG

4.02e-031345245EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
MGLKGAWCFPWCGCR

C17orf114

1

A0A1B0GUV1
CAKSLSGGWWFGTCS

ANGPTL4

341

Q9BY76
RWGKCCLPWALGCRK

ATP13A3

1166

Q9H7F0
AGWKVGNWSKCSRNC

ADAMTS12

1366

P58397
WALKSWAPCSKACGG

ADAMTS14

851

Q8WXS8
HWCDSSPCKNGGKCW

NOTCH1

1061

P46531
LQTVPKGGWKCKWCV

KMT2C

1041

Q8NEZ4
DGRRDCSKVWCGWKP

JAG2

896

Q9Y219
CSKVWCGWKPCLLAG

JAG2

901

Q9Y219
GEWTKWTACSRSCGG

ADAMTSL2

51

Q86TH1
CSCKAGWRGWSCTDN

PGAP6

521

Q9HCN3
LTCCWWPQGSQGKTL

GPR180

11

Q86V85
WEGCMKGGLCRAWNP

POM121L12

116

Q8N7R1
WRFGSWTPCSATCGK

ADAMTS9

1186

Q9P2N4
GRCPKWKAGAWSQCS

ADAMTS9

1496

Q9P2N4
WKAGAWSQCSVSCGR

ADAMTS9

1501

Q9P2N4
LWDCGGDAKFESCWP

IFT22

61

Q9H7X7
SKWCVSPKGPWTCVG

DNASE2

296

O00115
CGWRTAVAPAKFCLW

FAM87A

41

P0C7U9
GRCWAGSLWLFKDPC

WDR77

51

Q9BQA1
NSSGKQPWFCAWKRG

SPHKAP

951

Q2M3C7
KWNRTVRTCCPGWGG

SSPOP

86

A2VEC9
WSPWAKCLGPCGSQS

SSPOP

1916

A2VEC9
TGACVCKPGWWGRRC

SCARF1

176

Q14162
TKVPAWGCCPASWKS

CLEC6A

71

Q6EIG7
ICGNKIHSKWACWTP

SYCP2

606

Q9BX26
CKAGWRGWGCTDSAD

TMEM8B

211

A6NDV4
CWCVNSWGKELPGSR

TG

636

P01266
LGPWGKWRCLCDLGK

THSD8

56

A0A1W2PP97