Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

MMRN1 FBN1 FBN2

3.79e-0712253GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

MMRN1 FBN1 FBN2

6.25e-0714253GO:0097493
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MMRN1 FBN1 FBN2 SSPOP

8.25e-05188254GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

MMRN1 FBN1 FBN2 CUBN DLL1 DLL4

2.62e-04749256GO:0005509
GeneOntologyMolecularFunctionNotch binding

DLL1 DLL4

5.18e-0427252GO:0005112
GeneOntologyMolecularFunctionreceptor ligand activity

FBN1 FBN2 DLL1 DLL4

4.46e-03547254GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

FBN1 FBN2 DLL1 DLL4

4.67e-03554254GO:0030546
GeneOntologyMolecularFunctionsignaling receptor regulator activity

FBN1 FBN2 DLL1 DLL4

6.77e-03616254GO:0030545
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

6.51e-064222GO:0035583
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

3.03e-058222GO:0071694
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

5.94e-0511222GO:0035581
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

HHIP FBN1 FBN2 DLL1 SMAD2

6.17e-05412225GO:0090287
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

8.41e-0513222GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

8.41e-0513222GO:1900116
GeneOntologyBiologicalProcessdorsal/ventral pattern formation

HHIP DLL4 SMAD2

1.95e-04107223GO:0009953
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

HHIP FBN1 FBN2 DLL1 DLL4 SMAD2

2.04e-04850226GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

HHIP FBN1 FBN2 DLL1 DLL4 SMAD2

2.50e-04883226GO:0070848
GeneOntologyBiologicalProcessnegative regulation of myeloid cell differentiation

GPR137 FBN1 DLL1

3.77e-04134223GO:0045638
GeneOntologyBiologicalProcesspericardium development

DLL4 SMAD2

4.04e-0428222GO:0060039
GeneOntologyBiologicalProcesscirculatory system development

HHIP MEF2B FBN1 DLL1 DLL4 RAPGEF3 SMAD2

5.39e-041442227GO:0072359
GeneOntologyBiologicalProcessaortic valve morphogenesis

DLL4 SMAD2

7.86e-0439222GO:0003180
GeneOntologyBiologicalProcessendothelium development

DLL1 DLL4 RAPGEF3

9.20e-04182223GO:0003158
GeneOntologyBiologicalProcessheart development

MEF2B FBN1 DLL1 DLL4 SMAD2

1.03e-03757225GO:0007507
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

FBN1 FBN2 SMAD2

1.07e-03192223GO:0017015
GeneOntologyBiologicalProcessaortic valve development

DLL4 SMAD2

1.09e-0346222GO:0003176
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

FBN1 FBN2 SMAD2

1.12e-03195223GO:1903844
GeneOntologyBiologicalProcessnegative regulation of Notch signaling pathway

DLL1 DLL4

1.19e-0348222GO:0045746
GeneOntologyBiologicalProcesssemi-lunar valve development

DLL4 SMAD2

1.29e-0350222GO:1905314
GeneOntologyBiologicalProcessneuroepithelial cell differentiation

DLL1 SMAD2

1.34e-0351222GO:0060563
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

DLL1 DLL4

1.45e-0353222GO:0045747
GeneOntologyBiologicalProcessregionalization

HHIP DLL1 DLL4 SMAD2

1.50e-03478224GO:0003002
GeneOntologyBiologicalProcesstrabecula morphogenesis

FBN2 DLL4

1.67e-0357222GO:0061383
GeneOntologyBiologicalProcessnegative regulation of osteoclast differentiation

GPR137 FBN1

1.79e-0359222GO:0045671
GeneOntologyBiologicalProcessheart valve morphogenesis

DLL4 SMAD2

2.04e-0363222GO:0003179
GeneOntologyBiologicalProcesspattern specification process

HHIP DLL1 DLL4 SMAD2

2.12e-03526224GO:0007389
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

1.06e-0413252GO:0001527
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

6.47e-06382HP:0012772
HumanPhenoDisproportionate tall stature

FBN1 FBN2 SMAD2

2.64e-054183HP:0001519
HumanPhenoAbnormal bleeding

FBN1 CUBN DLL4 SMAD2 POT1 CFHR3

3.11e-0553786HP:0001892
HumanPhenoCrumpled ear

FBN1 FBN2

3.23e-05682HP:0009901
HumanPhenoInternal hemorrhage

FBN1 DLL4 SMAD2 POT1 CFHR3

6.01e-0533985HP:0011029
HumanPhenoAbnormality of coagulation

FBN1 CUBN DLL4 SMAD2 POT1 CFHR3

9.17e-0564786HP:0001928
HumanPhenoSlender build

FBN1 FBN2 SMAD2

1.11e-046683HP:0001533
HumanPhenoAortic root aneurysm

FBN1 FBN2 SMAD2

1.32e-047083HP:0002616
HumanPhenoCutis marmorata

FBN1 DLL4 SMAD2

1.44e-047283HP:0000965
HumanPhenoDilatation of the ascending aorta

FBN1 FBN2 SMAD2

2.28e-048483HP:0005111
HumanPhenoAbnormality of habitus

FBN1 FBN2 SMAD2

2.53e-048783HP:0010718
HumanPhenoSlender long bone

FBN1 FBN2 SMAD2

2.71e-048983HP:0003100
HumanPhenoGracile long bones

FBN1 FBN2 SMAD2

2.71e-048983HP:0003061
HumanPhenoMucoid extracellular matrix accumulation

FBN1 SMAD2

3.64e-041982HP:0200146
HumanPhenoMedial degeneration

FBN1 SMAD2

3.64e-041982HP:0032079
HumanPhenoCystic medial necrosis

FBN1 SMAD2

3.64e-041982HP:0012180
HumanPhenoDescending thoracic aorta aneurysm

FBN1 SMAD2

3.64e-041982HP:0004959
HumanPhenoAbnormality of blood circulation

FBN1 DLL4 SMAD2 POT1 CFHR3

3.82e-0449885HP:0011028
HumanPhenoParoxysmal dyspnea

FBN1 SMAD2

4.04e-042082HP:0012763
HumanPhenoIncreased blood pressure

FBN1 DLL4 SMAD2 POT1 CFHR3

4.20e-0450885HP:0032263
HumanPhenoHypertension

FBN1 DLL4 SMAD2 POT1 CFHR3

4.20e-0450885HP:0000822
HumanPhenoDescending aortic dissection

FBN1 SMAD2

4.47e-042182HP:0012499
HumanPhenoCongenital malformation of the great arteries

FBN1 FBN2 DLL1 DLL4 SMAD2

5.08e-0452985HP:0011603
HumanPhenoChoroidal neovascularization

FBN2 CFHR3

5.37e-042382HP:0011506
HumanPhenoDural ectasia

FBN1 SMAD2

5.86e-042482HP:0100775
HumanPhenoCarotid artery dilatation

FBN1 SMAD2

5.86e-042482HP:0012163
HumanPhenoAbnormal spinal meningeal morphology

FBN1 SMAD2

6.36e-042582HP:0010303
HumanPhenoBicuspid aortic valve

FBN1 FBN2 SMAD2

6.39e-0411983HP:0001647
HumanPhenoAbnormal aortic valve cusp morphology

FBN1 FBN2 SMAD2

6.71e-0412183HP:0031567
HumanPhenoThoracic aortic aneurysm

FBN1 FBN2 SMAD2

6.71e-0412183HP:0012727
HumanPhenoAscending aortic dissection

FBN1 SMAD2

6.88e-042682HP:0004933
HumanPhenoAbnormal systemic blood pressure

FBN1 DLL4 SMAD2 POT1 CFHR3

7.17e-0456985HP:0030972
HumanPhenoAbdominal aortic aneurysm

FBN1 FBN2 SMAD2

7.38e-0412583HP:0005112
HumanPhenoSingle central incisor

DLL1 SMAD2

7.43e-042782HP:0001573
HumanPhenoAbnormal ascending aorta morphology

FBN1 SMAD2

7.43e-042782HP:0031784
HumanPhenoSolitary median maxillary central incisor

DLL1 SMAD2

7.43e-042782HP:0006315
HumanPhenoAbnormal morphology of the choroidal vasculature

FBN2 CFHR3

7.99e-042882HP:0025568
HumanPhenoArachnodactyly

FBN1 FBN2 SMAD2

8.85e-0413383HP:0001166
HumanPhenoAbnormal uvea morphology

FBN1 FBN2 DLL1 SMAD2 POT1 CFHR3

8.99e-0496586HP:0000553
HumanPhenoAbnormality of blood volume homeostasis

FBN1 SMAD2

1.05e-033282HP:0011104
HumanPhenoHypovolemia

FBN1 SMAD2

1.05e-033282HP:0011106
HumanPhenoPeripheral arterial stenosis

FBN1 SMAD2

1.11e-033382HP:0004950
HumanPhenoAbnormal atrioventricular valve morphology

FBN1 FBN2 DLL4 SMAD2

1.23e-0335084HP:0006705
HumanPhenoAbnormal aortic morphology

FBN1 FBN2 DLL1 SMAD2

1.41e-0336384HP:0030963
HumanPhenoStriae distensae

FBN1 SMAD2

1.48e-033882HP:0001065
HumanPhenoIschemic stroke

FBN1 SMAD2

1.48e-033882HP:0002140
HumanPhenoSlender finger

FBN1 FBN2 SMAD2

1.49e-0315983HP:0001238
HumanPhenoCerebral infarct

FBN1 SMAD2

1.55e-033982HP:0025722
HumanPhenoSubarachnoid hemorrhage

FBN1 SMAD2

1.55e-033982HP:0002138
HumanPhenoScaphocephaly

FBN1 FBN2

1.63e-034082HP:0030799
HumanPhenoAortic dissection

FBN1 SMAD2

1.63e-034082HP:0002647
HumanPhenoAortic dilatation

FBN1 FBN2 SMAD2

1.75e-0316883HP:0001724
HumanPhenoLong toe

FBN1 FBN2 SMAD2

1.75e-0316883HP:0010511
HumanPhenoAortic aneurysm

FBN1 FBN2 SMAD2

1.75e-0316883HP:0004942
HumanPhenoJoint dislocation

FBN1 FBN2 DLL1 SMAD2

1.85e-0339084HP:0001373
HumanPhenoLens dislocation

FBN1 FBN2

1.89e-034382HP:0000665
HumanPhenoEctopia lentis

FBN1 FBN2

1.89e-034382HP:0001083
HumanPhenoAbnormal systemic arterial morphology

FBN1 FBN2 DLL1 DLL4 SMAD2

1.99e-0370885HP:0011004
HumanPhenoPremature birth

FBN1 DLL1 DLL4

2.03e-0317783HP:0001622
HumanPhenoAbnormal aortic morphology

FBN1 FBN2 DLL1 SMAD2

2.05e-0340184HP:0001679
HumanPhenoPectus carinatum

FBN1 FBN2 SMAD2

2.06e-0317883HP:0000768
HumanPhenoDuodenal atresia

FBN2 DLL1

2.07e-034582HP:0002247
HumanPhenoAbnormal heart valve physiology

FBN1 FBN2 DLL4 SMAD2

2.09e-0340384HP:0031653
HumanPhenoPregnancy history

FBN1 DLL1 SMAD2

2.20e-0318283HP:0002686
HumanPhenoPast medical history

FBN1 DLL1 SMAD2

2.24e-0318383HP:0032443
HumanPhenoEsophageal varix

DLL4 POT1

2.25e-034782HP:0002040
HumanPhenoReticulocytosis

CUBN CFHR3

2.25e-034782HP:0001923
HumanPhenoAbnormal morphology of the great vessels

FBN1 FBN2 DLL1 DLL4 SMAD2

2.38e-0373685HP:0030962
HumanPhenoMetatarsus adductus

FBN1 FBN2

2.65e-035182HP:0001840
HumanPhenoDilatation of the cerebral artery

FBN1 SMAD2

2.65e-035182HP:0004944
HumanPhenoAtrioventricular valve regurgitation

FBN1 FBN2 DLL4

2.72e-0319683HP:0034376
HumanPhenoAbnormal pulmonary valve morphology

FBN1 DLL4 SMAD2

2.80e-0319883HP:0001641
HumanPhenoAplasia/Hypoplasia of the skin

FBN1 DLL4 SMAD2

2.93e-0320183HP:0008065
HumanPhenoThrombocytopenia

CUBN DLL4 POT1 CFHR3

3.45e-0346184HP:0001873
HumanPhenoAbnormal atrioventricular valve physiology

FBN1 FBN2 DLL4

3.55e-0321583HP:0031650
HumanPhenoVascular dilatation

FBN1 FBN2 SMAD2

3.55e-0321583HP:0002617
HumanPhenoLimited elbow extension

FBN1 FBN2

3.65e-036082HP:0001377
HumanPhenoDolichocephaly

FBN1 FBN2 SMAD2

3.74e-0321983HP:0000268
HumanPhenoTransient ischemic attack

FBN1 SMAD2

3.77e-036182HP:0002326
HumanPhenoLack of skin elasticity

FBN1 SMAD2

3.77e-036182HP:0100679
DomainEGF_3

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 SSPOP VWDE

1.76e-11235269PS50026
DomainEGF_1

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 SSPOP VWDE

3.65e-11255269PS00022
DomainEGF_2

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 SSPOP VWDE

5.15e-11265269PS01186
DomainEGF

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 VWDE

7.17e-10235268SM00181
DomainEGF-like_dom

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 VWDE

1.13e-09249268IPR000742
DomainEGF-like_CS

MMRN1 HHIP FBN1 FBN2 CUBN DLL1 DLL4 VWDE

1.64e-09261268IPR013032
DomainEGF-type_Asp/Asn_hydroxyl_site

MMRN1 FBN1 FBN2 CUBN DLL1 DLL4

6.08e-09106266IPR000152
DomainEGF_CA

MMRN1 FBN1 FBN2 CUBN DLL1 DLL4

1.42e-08122266SM00179
DomainEGF-like_Ca-bd_dom

MMRN1 FBN1 FBN2 CUBN DLL1 DLL4

1.57e-08124266IPR001881
DomainASX_HYDROXYL

FBN1 FBN2 CUBN DLL1 DLL4

2.39e-07100265PS00010
DomainGrowth_fac_rcpt_

FBN1 FBN2 CUBN DLL1 DLL4

2.18e-06156265IPR009030
DomainFBN

FBN1 FBN2

5.59e-063262IPR011398
DomainEGF_Ca-bd_CS

FBN1 FBN2 CUBN DLL1

9.36e-0697264IPR018097
DomainEGF_CA

FBN1 FBN2 CUBN DLL1

1.02e-0599264PS01187
DomainDSL

DLL1 DLL4

1.12e-054262PF01414
DomainDSL

DLL1 DLL4

1.12e-054262SM00051
DomainDSL

DLL1 DLL4

1.86e-055262PS51051
DomainNotch_ligand_N

DLL1 DLL4

1.86e-055262IPR011651
DomainMNNL

DLL1 DLL4

1.86e-055262PF07657
DomainDSL

DLL1 DLL4

1.86e-055262IPR001774
DomainEGF

MMRN1 CUBN DLL1 DLL4

2.63e-05126264PF00008
DomainTLV_coat

ERVV-1 ERVV-2

3.90e-057262PF00429
DomainTB

FBN1 FBN2

3.90e-057262PF00683
DomainTLV/ENV_coat_polyprotein

ERVV-1 ERVV-2

5.19e-058262IPR018154
Domain-

FBN1 FBN2

5.19e-0582623.90.290.10
DomainTB_dom

FBN1 FBN2

6.67e-059262IPR017878
DomainTB

FBN1 FBN2

6.67e-059262PS51364
DomainVWFD

SSPOP VWDE

2.21e-0416262PS51233
DomainVWD

SSPOP VWDE

2.21e-0416262SM00216
DomainVWF_type-D

SSPOP VWDE

2.21e-0416262IPR001846
DomainVWD

SSPOP VWDE

2.21e-0416262PF00094
DomainEGF_CA

FBN1 FBN2 CUBN

2.27e-0486263PF07645
DomainEMI

MMRN1 SSPOP

2.50e-0417262PS51041
DomaincEGF

FBN1 FBN2

5.93e-0426262PF12662
DomaincEGF

FBN1 FBN2

5.93e-0426262IPR026823
DomainhEGF

FBN2 DLL1

6.89e-0428262PF12661
DomainLdl_recept_a

LDLRAD1 SSPOP

1.78e-0345262PF00057
Domain-

LDLRAD1 SSPOP

1.86e-03462624.10.400.10
DomainLDLRA_1

LDLRAD1 SSPOP

2.02e-0348262PS01209
DomainLDLa

LDLRAD1 SSPOP

2.11e-0349262SM00192
DomainLDLRA_2

LDLRAD1 SSPOP

2.11e-0349262PS50068
DomainLDrepeatLR_classA_rpt

LDLRAD1 SSPOP

2.11e-0349262IPR002172
DomainCUB_dom

MGAT3 CUBN

2.84e-0357262IPR000859
DomainEGF_extracell

HHIP DLL4

3.14e-0360262IPR013111
DomainEGF_2

HHIP DLL4

3.14e-0360262PF07974
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2 SMAD2

3.30e-0625173M39713
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

DLL1 DLL4

2.86e-057172M27199
PathwayKEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

DLL1 DLL4

2.86e-057172M47805
PathwayPID_NOTCH_PATHWAY

DLL1 DLL4 SSPOP

4.54e-0559173M17
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

DLL1 DLL4

4.90e-059172M47866
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL1 DLL4

1.06e-0413172M47423
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

DLL1 DLL4

1.42e-0415172M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

DLL1 DLL4

1.63e-0416172M47424
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

DLL1 DLL4

1.84e-0417172M39389
PathwayREACTOME_SIGNALING_BY_NOTCH3

DLL1 DLL4

2.31e-0419172MM15594
PathwayWP_PROGERIAASSOCIATED_LIPODYSTROPHY

FBN1 SMAD2

3.12e-0422172M42534
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

DLL1 DLL4

3.12e-0422172M27210
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

DLL1 DLL4

4.04e-0425172M27879
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DLL1 DLL4

4.72e-0427172M39545
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

DLL1 DLL4

6.24e-0431172M592
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

6.65e-0432172MM14854
PathwayREACTOME_SIGNALING_BY_NOTCH2

DLL1 DLL4

7.07e-0433172M604
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

DLL1 DLL4 SMAD2

8.84e-04161173M39770
PathwayWP_NEOVASCULARIZATION_PROCESSES

DLL4 SMAD2

8.89e-0437172M39506
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

8.89e-0437172M27134
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 SMAD2

9.38e-0438172MM14874
PathwayREACTOME_SIGNALING_BY_NOTCH

DLL1 DLL4

9.88e-0439172MM14604
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

9.88e-0439172MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

1.26e-0344172M26969
PathwayWP_NOTCH_SIGNALING_WP268

DLL1 DLL4

1.31e-0345172M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

DLL1 DLL4

1.37e-0346172MM15971
PathwayPID_PS1_PATHWAY

DLL1 SSPOP

1.37e-0346172M70
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

DLL1 DLL4

1.43e-0347172M7946
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 SMAD2

1.43e-0347172M646
PathwayREACTOME_SIGNALING_BY_NOTCH3

DLL1 DLL4

1.56e-0349172M618
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

DLL1 DLL4

2.17e-0358172M29616
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

FBN1 SMAD2

2.25e-0359172M39886
PathwayWP_NOTCH_SIGNALING_WP61

DLL1 DLL4

2.40e-0361172M39540
PathwayWP_CANCER_PATHWAYS

HHIP DLL1 DLL4 SMAD2

2.71e-03507174M48302
PathwayREACTOME_SIGNALING_BY_NOTCH1

DLL1 DLL4

3.51e-0374172M616
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

FBN1 SMAD2

3.80e-0377172MM14670
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

DLL1 DLL4

4.30e-0382172MM15922
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

FBN1 SMAD2

5.61e-0394172M1041
PathwayWP_NEURAL_CREST_DIFFERENTIATION

DLL1 DLL4

5.96e-0397172MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

DLL1 DLL4

6.44e-03101172M39448
PathwayWP_COMPREHENSIVE_IL17A_SIGNALING

FBN1 SMAD2

7.60e-03110172MM16642
PathwayWP_1P36_COPY_NUMBER_VARIATION_SYNDROME

DLL1 SMAD2

7.87e-03112172M48072
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN1 FBN2

8.14e-03114172MM14571
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

FBN1 SMAD2

8.70e-03118172MM15588
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

DLL1 DLL4

8.70e-03118172M39852
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FBN1 FBN2 SMAD2

3.38e-071827335503090
Pubmed

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo.

DLL1 DLL4

5.80e-07227215146182
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

5.80e-07227212399449
Pubmed

Induction of T-cell development by Delta-like 4-expressing fibroblasts.

DLL1 DLL4

5.80e-07227223988616
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

5.80e-07227221851253
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

5.80e-07227212429739
Pubmed

In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects.

DLL1 DLL4

5.80e-07227215728481
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

5.80e-07227224833718
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

5.80e-07227230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

5.80e-07227221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

5.80e-07227215131124
Pubmed

Suppression of Th2 cell development by Notch ligands Delta1 and Delta4.

DLL1 DLL4

5.80e-07227218209061
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

5.80e-07227224265020
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

5.80e-07227212524050
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

5.80e-07227220529844
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

5.80e-07227225524144
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

5.80e-07227220404337
Pubmed

Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development.

DLL1 DLL4

5.80e-07227216393955
Pubmed

Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes.

DLL1 DLL4

5.80e-07227220548034
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

5.80e-07227223133647
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

5.80e-0722728791520
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

5.80e-0722728120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

5.80e-07227235419902
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

5.80e-0722728307578
Pubmed

Isolation and characterization of the notch ligand delta4.

DLL1 DLL4

5.80e-07227211035934
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

5.80e-07227216407178
Pubmed

Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice.

DLL1 DLL4

5.80e-07227231934853
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

5.80e-07227210504303
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

5.80e-0722721852206
Pubmed

Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.

ERVV-1 ERVV-2

5.80e-07227223555306
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

5.80e-07227210359653
Pubmed

Dengue virus up-regulates expression of notch ligands Dll1 and Dll4 through interferon-β signalling pathway.

DLL1 DLL4

5.80e-07227225041739
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-1 ERVV-2

5.80e-07227218826608
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

5.80e-0722727744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

5.80e-07227226408953
Pubmed

DLL1- and DLL4-Mediated Notch Signaling Is Essential for Adult Pancreatic Islet Homeostasis.

DLL1 DLL4

5.80e-07227232029480
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

5.80e-07227218006876
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

HHIP FBN1 FBN2

1.67e-063027332882513
Pubmed

Heritable Thoracic Aortic Disease Overview

FBN1 FBN2 SMAD2

1.67e-063027320301299
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

FBN1 FBN2

1.74e-06327210825173
Pubmed

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

DLL1 DLL4

1.74e-06327221372153
Pubmed

Lack of Delta like 1 and 4 expressions in nude thymus anlages.

DLL1 DLL4

1.74e-06327216095582
Pubmed

Expanding the phenotypic spectrum of Mendelian connective tissue disorders to include prominent kidney phenotypes.

FBN2 SMAD2

1.74e-06327234355836
Pubmed

Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.

DLL1 DLL4

1.74e-06327212684674
Pubmed

Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.

DLL1 DLL4

1.74e-06327223839946
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

FBN1 FBN2

1.74e-06327230201140
Pubmed

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

FBN1 FBN2

1.74e-06327220855508
Pubmed

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

FBN1 FBN2 SMAD2

1.85e-063127325762570
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

DLL1 DLL4 SMAD2

2.69e-063527321252157
Pubmed

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.

FBN1 FBN2 SMAD2

2.93e-063627335167946
Pubmed

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

DLL1 DLL4

3.48e-06427218824585
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2

3.48e-06427212429738
Pubmed

Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.

DLL1 DLL4

3.48e-06427220602435
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

FBN1 FBN2

3.48e-06427225406291
Pubmed

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

FBN1 FBN2

3.48e-06427220729550
Pubmed

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.

DLL1 DLL4

3.48e-06427232820046
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2

3.48e-06427225034023
Pubmed

No evidence for a functional role of bi-directional Notch signaling during angiogenesis.

DLL1 DLL4

3.48e-06427223300864
Pubmed

Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development.

DLL1 DLL4

3.48e-06427223162128
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2

3.48e-06427216835936
Pubmed

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.

DLL1 DLL4

3.48e-06427228319044
Pubmed

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

FBN1 FBN2

5.80e-06527226601954
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

DLL1 DLL4

5.80e-06527221726900
Pubmed

Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.

DLL1 DLL4

5.80e-06527219723503
Pubmed

Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.

DLL1 DLL4

5.80e-06527219110448
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBN1 FBN2

5.80e-06527217255108
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 FBN2

5.80e-06527234411563
Pubmed

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.

DLL1 DLL4

5.80e-06527230181175
Pubmed

Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.

FBN1 FBN2

5.80e-06527212590922
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

FBN1 FBN2

5.80e-06527223493297
Pubmed

Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.

HHIP DLL1 DLL4

6.61e-064727332747435
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

DLL1 DLL4 SMAD2

7.05e-064827335247391
Pubmed

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.

DLL1 DLL4

8.69e-06627219050235
Pubmed

BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein.

FBN1 SMAD2

8.69e-06627217015622
Pubmed

Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.

DLL1 DLL4

8.69e-06627219217325
Pubmed

Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing.

DLL1 DLL4

8.69e-06627235091558
Pubmed

Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.

FBN1 FBN2

8.69e-0662727873879
Pubmed

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.

ERVV-1 ERVV-2

8.69e-06627223085571
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

MMRN1 FBN1 FBN2 SSPOP

9.93e-0617527428071719
Pubmed

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.

DLL1 DLL4

1.22e-05727226114479
Pubmed

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.

DLL1 DLL4

1.22e-05727224025447
Pubmed

GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.

DLL1 DLL4

1.22e-05727232060138
Pubmed

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.

DLL1 DLL4

1.22e-05727230289388
Pubmed

Regulation of limb patterning by extracellular microfibrils.

FBN1 FBN2

1.22e-05727211470817
Pubmed

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.

DLL1 DLL4

1.22e-05727221238454
Pubmed

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

DLL1 DLL4

1.22e-05727227576369
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN1 FBN2

1.62e-05827223055981
Pubmed

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.

FBN1 FBN2

1.62e-05827231201465
Pubmed

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.

DLL1 DLL4

1.62e-05827224647000
Pubmed

Syncytins expressed in human placental trophoblast.

ERVV-1 ERVV-2

1.62e-05827233504453
Pubmed

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

FBN1 FBN2

1.62e-05827218339631
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL1 DLL4

2.08e-05927216245338
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 FBN2

2.08e-05927212122015
Pubmed

Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium.

DLL1 DLL4

2.08e-05927217605079
Pubmed

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.

DLL1 DLL4

2.08e-05927228714968
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FBN2

2.08e-05927238844137
Pubmed

Monitoring Notch1 activity in development: evidence for a feedback regulatory loop.

DLL1 DLL4

2.08e-05927217685488
Pubmed

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.

DLL1 DLL4

2.08e-05927220727173
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

DLL1 DLL4

2.08e-05927210837027
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN1 FBN2 SSPOP

2.30e-057127333541421
InteractionMFAP5 interactions

FBN1 FBN2 DLL1 VWDE

5.65e-0752264int:MFAP5
InteractionNTN5 interactions

FBN1 FBN2 VWDE

3.79e-0624263int:NTN5
InteractionFBN2 interactions

FBN1 FBN2 SMAD2

7.90e-0565263int:FBN2
InteractionMFAP2 interactions

FBN1 FBN2

1.05e-0412262int:MFAP2
CytobandEnsembl 112 genes in cytogenetic band chr4q31

TMEM184C HHIP

4.20e-03164272chr4q31
CoexpressionNABA_ECM_GLYCOPROTEINS

MMRN1 FBN1 FBN2 SSPOP VWDE

1.13e-06191265MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

MMRN1 FBN1 FBN2 SSPOP VWDE

1.29e-06196265M3008
CoexpressionNABA_CORE_MATRISOME

MMRN1 FBN1 FBN2 SSPOP VWDE

6.16e-06270265MM17057
CoexpressionNABA_CORE_MATRISOME

MMRN1 FBN1 FBN2 SSPOP VWDE

6.73e-06275265M5884
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_DN

MMRN1 HHIP DLL4 RAPGEF3 CNR2

1.07e-04491265MM455
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL1 DLL4

1.13e-0416262M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL1 DLL4

1.13e-0416262MM1296
CoexpressionINGRAM_SHH_TARGETS_UP

HHIP FBN1 FBN2

2.54e-04125263M1320
CoexpressionAtlasplacenta

ERVV-1 FBN1 FBN2 ERVV-2 DLL4

3.83e-05349245placenta
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3 CNR2

3.70e-061762743494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3 CNR2

3.70e-06176274d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCellfacs-MAT-Fat-3m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL1 DLL4 RAPGEF3

5.33e-06193274e164f6403a8b541ced08a6feec915d2e855036ea
ToppCellfacs-MAT-Fat-3m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL1 DLL4 RAPGEF3

5.33e-06193274b32533afeff1905e188becaa09079e9699722e4b
ToppCellfacs-MAT-Fat-3m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL1 DLL4 RAPGEF3

5.33e-061932742ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP FBN1 FBN2 DLL1

6.02e-06199274e78f661b40da34768469549b6e755d330be6bbd8
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocholangiocarcinoma_(Mixed)-1|TCGA-Liver / Sample_Type by Project: Shred V9

ARSH IGFL2 FBN2

3.77e-0510827390c95fe363ced0d87f77e44165ed3cc319a6dfdf
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

RNF224 IGFL2 FBN2

1.17e-041582733bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

MMRN1 IGFL2 FBN1

1.17e-041582730d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP DLL1 DLL4

1.21e-041602736215ac6123a295f3c2f033786602a57b2e2e1177
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

MMRN1 HHIP CNR2

1.30e-0416427336e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

MMRN1 FBN1 DLL4

1.38e-0416727397d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellIIH-naiveBc|IIH / Condition, Cell_class and T cell subcluster

MGAT3 C11orf16 CNR2

1.40e-041682738450ed6720d308c711dfbc76652e5821be7b8e93
ToppCellIIH-naiveBc-|IIH / Condition, Cell_class and T cell subcluster

MGAT3 C11orf16 CNR2

1.40e-0416827327b500f79aedc4669988670c92ff1a47dcbdf2a0
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MMRN1 FBN1 DLL4

1.48e-0417127307ff7059071da83da1d8f266a586573920d75b58
ToppCellT_cells-CD56_bright_CD16-_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ARSH MMRN1 DLL1

1.50e-04172273980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 RAPGEF3 CNR2

1.50e-04172273a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

MMRN1 DLL4 SSPOP

1.50e-04172273c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 LDLRAD1 RAPGEF3

1.55e-0417427346bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LDLRAD1 C11orf16 SSPOP

1.55e-04174273f1510b0f7771936adf29ae3572feab55db31832b
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LDLRAD1 C11orf16 SSPOP

1.55e-041742735d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM184C HHIP FBN1

1.66e-0417827327497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM184C HHIP FBN1

1.66e-04178273d348a9550db940d204706529759dc51e30506b5f
ToppCellcontrol-NK_CD56bright|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MMRN1 DLL1 CNR2

1.66e-04178273f3d0bc9a39ed94785676f10c285c5b031bc93aae
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMRN1 FBN1 VWDE

1.69e-041792732f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

MMRN1 FBN1 VWDE

1.69e-0417927319fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMRN1 FBN1 VWDE

1.69e-041792734bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMRN1 FBN1 VWDE

1.69e-041792733e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

MMRN1 FBN1 VWDE

1.69e-0417927350a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MMRN1 FBN1 VWDE

1.74e-0418127354a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MMRN1 FBN1 VWDE

1.74e-041812735b84625b1d3737708001b64f6da9360330d39a27
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

IGFL2 FBN1 FBN2

1.74e-04181273bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MMRN1 FBN1 VWDE

1.74e-04181273e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HHIP FBN1 FBN2

1.74e-041812739b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 FBN1 RAPGEF3

1.77e-04182273d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HHIP MGAT3 FBN2

1.77e-04182273812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MMRN1 DLL1 RAPGEF3

1.80e-04183273c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

CUBN DLL1 DLL4

1.86e-04185273ad52970e88e8947ef256095bd4b40229b912d58a
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 FBN2

1.86e-04185273785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 FBN2

1.86e-0418527397a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 FBN2

1.89e-0418627394d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell367C-Endothelial_cells-Endothelial-D|367C / Donor, Lineage, Cell class and subclass (all cells)

MMRN1 DLL4 RAPGEF3

1.92e-041872731342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell367C-Endothelial_cells-Endothelial-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

MMRN1 DLL4 RAPGEF3

1.92e-041872737aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

MMRN1 DLL1 RAPGEF3

1.92e-04187273e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 DLL4 SSPOP

1.95e-04188273524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 DLL1 CFHR3

1.95e-04188273997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 DLL4 SSPOP

1.95e-04188273d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMRN1 DLL4 RAPGEF3

1.98e-04189273e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LDLRAD1 C11orf16

1.98e-04189273dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMRN1 DLL4 RAPGEF3

1.98e-04189273ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMRN1 DLL4 RAPGEF3

1.98e-04189273f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 ERVV-1 DLL4

1.98e-04189273a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.01e-041902731ff2295c9fc94ea21fff286706b739d0deb032d0
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.01e-04190273d415c8f3d69a8142e95307aeabc6d0e812cd5165
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.01e-0419027361f2f9fb4b8f47a2a669f6b052214d2ce0c194cd
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMRN1 CUBN DLL4

2.01e-0419027306bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MMRN1 DLL1 CNR2

2.04e-041912737a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

MMRN1 DLL1 CNR2

2.04e-04191273e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMRN1 DLL1 CNR2

2.04e-04191273f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MMRN1 DLL1 CNR2

2.04e-04191273c023ca893ceae19b54967096f6e2588dc39fa268
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMRN1 DLL1 CNR2

2.04e-041912731161e465c50c2071764279e01cf08b1048cce0e3
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.08e-04192273945153c41dde6e90d103206955e1707b54eb0665
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.08e-041922736ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell15-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

MMRN1 FBN1 DLL4

2.11e-041932736ea0444fc3dc156997129387184e6418947f4b12
ToppCellT_cells-CD56_bright_CD16-_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

MMRN1 DLL1 CNR2

2.11e-04193273826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

MMRN1 DLL1 CNR2

2.11e-041932738b1e7a226a6057e1097c1525984127b54e823876
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.11e-04193273aaa5042388dc451bff384c6bb237348f08280a08
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.11e-041932734aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCell15-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

MMRN1 FBN1 DLL4

2.11e-04193273b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCellEndothelial-endothelial_cell_of_vein|World / Lineage, Cell type, age group and donor

MMRN1 DLL1 RAPGEF3

2.14e-041942733cbd9622a68e89add90e589867d88c83c5a33476
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 DLL4 RAPGEF3

2.17e-04195273ccfb80e3bfdf5304fa798e0a47b473955ecc0c6d
ToppCell(6)_Endothelial-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MMRN1 DLL4 RAPGEF3

2.17e-04195273c0005a5f2dc63a0cc254c45ac89a2f42df6f8bde
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.17e-0419527398d79f6a8a5cc86a219efe8db9f9535d7ad4c5be
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAT3 LDLRAD1 C11orf16

2.17e-04195273ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.17e-04195273ea0627ffe1750dbdd48006d251c0ba4cadd32faf
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.17e-041952733b95a989adb99591b44704ff4c496a1c6cb0bb18
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MMRN1 DLL1 RAPGEF3

2.17e-04195273cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.20e-04196273b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARSH MEF2B C11orf16

2.20e-04196273a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.20e-041962739a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellfacs-Lung-ENDOMUCIN|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.20e-0419627369f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCellfacs-Lung-ENDOMUCIN-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL1 DLL4 RAPGEF3

2.20e-04196273f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.20e-04196273ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.20e-04196273039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.20e-0419627304dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBN1 CUBN DLL4

2.24e-04197273ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright|ICU-SEP / Disease, condition lineage and cell class

MMRN1 DLL1 CNR2

2.24e-04197273c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

MMRN1 DLL1 CNR2

2.24e-04197273cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP FBN2 DLL1

2.24e-041972732e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

MMRN1 DLL4 RAPGEF3

2.24e-041972737caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP FBN2 DLL1

2.24e-041972731da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

MMRN1 DLL1 CNR2

2.24e-04197273ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MMRN1 DLL4 RAPGEF3

2.24e-04197273951f18f326967206adbbfc422cce9eea3d2e0854
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 DLL4 RAPGEF3

2.24e-04197273488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMRN1 CUBN DLL4

2.24e-041972739e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN1 DLL4 RAPGEF3

2.27e-04198273ff8a9adc1302a4679ccdfe9ef95ef53e4c7a5391
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP FBN1 DLL1

2.27e-0419827309be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell368C-Endothelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

MMRN1 DLL4 RAPGEF3

2.27e-041982739a2c2201baee51581733e183065298a97eba4553
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

MMRN1 DLL1 DLL4

2.27e-0419827370d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP FBN2 DLL1

2.27e-041982734a4566f86c9365a41b4cfd1609eac09bd73b3f34
ComputationalAdhesion molecules.

MMRN1 FBN1 FBN2

5.74e-04141133MODULE_122
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

1.45e-063212DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

2.89e-064212DOID:0060249 (is_implicated_in)
DiseaseGeleophysic dysplasia

FBN1 SMAD2

4.82e-065212C3489726
DiseaseAcromicric Dysplasia

FBN1 SMAD2

4.82e-065212C0265287
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 SMAD2

7.11e-0653213C4707243
Diseasepancreatic ductal adenocarcinoma (is_marker_for)

SMAD2 CFHR3

1.68e-0427212DOID:3498 (is_marker_for)
Diseaseovarian cancer (is_implicated_in)

SMAD2 POT1

7.26e-0456212DOID:2394 (is_implicated_in)
DiseaseAbnormality of refraction

HHIP FBN1 FBN2 POT1

1.18e-03673214HP_0000539
DiseaseColorectal Carcinoma

HHIP FBN2 CUBN SMAD2

1.38e-03702214C0009402
Diseasedilated cardiomyopathy (implicated_via_orthology)

DLL1 DLL4

1.47e-0380212DOID:12930 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KHFPPLCCCPPWAMG

TMEM184C

151

Q9NVA4
KPWLQPCCGTFPFCG

ARSH

536

Q5FYA8
GYCSKPAECLCRPGW

DLL4

231

Q9NR61
PPCLWYFLPTLGCFC

LINC00518

101

Q8N0U6
RWACTPPGYVFLCGP

ERVV-2

246

B6SEH9
YLPLMGWTCCPRPCS

CNR2

166

P34972
GPPASYCAKLCEPQW

C8orf76

26

Q96K31
CVCLPGWHGPSCGVP

MGAT3

171

Q09327
SLDWRCCPGYSGPKC

MMRN1

266

Q13201
GPLPFWLLYCCPVCL

GPR137

91

Q96N19
RGYPLLWPAPCCSCH

GPR137

396

Q96N19
RWACTPPGYVFLCGP

ERVV-1

246

B6SEH8
PVTVCPPCGPGWWRC

LDLRAD1

156

Q5T700
QSLCGLGPPCAGCPW

MEF2B

311

Q02080
CICPPQWKGPLCSAD

CUBN

156

O60494
GWSPAVPCLRKCYFP

CFHR3

76

Q02985
VCNPGWKGPYCTEPI

DLL1

211

O00548
WKGPYCTEPICLPGC

DLL1

216

O00548
YCCPGWKTLPGGNQC

FBN1

66

P35555
PWLCQPAPRCGDKIY

IGFL2

31

Q6UWQ7
YCCPGWKTLPGGNQC

FBN2

96

P35556
PYCPLGSCPQGWVLV

SSPOP

2001

A2VEC9
LLCQPGGCPLPCGWS

SSPOP

2706

A2VEC9
CTDLPCPVPGGWCPW

SSPOP

3401

A2VEC9
CPPGIKIDAYPWLEC

POT1

591

Q9NUX5
WGCGSLCCPPLGSPE

RNF224

141

P0DH78
YCTPTGKCCCSPGWE

HHIP

616

Q96QV1
CLCGCPPCGTTWWPL

C11orf16

281

Q9NQ32
TPDICQCKPGWYGPT

VWDE

1406

Q8N2E2
YWVATELCLCPVPGP

RAPGEF3

716

O95398
YGWHPATVCKIPPGC

SMAD2

366

Q15796