Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCN1 CLCN2 CLCN4

5.69e-05111433GO:0005247
MousePhenofused cornea and lens

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.47e-06241185MP:0001307
MousePhenoabsent pinna reflex

AGAP5 CDH23 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6

9.93e-06891187MP:0006358
MousePhenoabnormal pinna reflex

AGAP5 CDH23 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6

2.28e-051011187MP:0001485
MousePhenoabnormal vestibular system physiology

CDH23 IREB2 CSF1 ATP2B2 SLC4A11

5.58e-05491185MP:0004742
MousePhenosmall frontal bone

B3GLCT NELL1 ALKBH1 HCFC1

6.25e-05261184MP:0004377
MousePhenoabnormal auditory brainstem response

AGAP5 CDH23 REST PCYOX1L CSF1 CLCN1 OSBPL2 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6 KLHL18 NIPBL SLC4A11

9.97e-0557611815MP:0004738
MousePhenoabnormal viscerocranium morphology

NCOA3 AGAP5 B3GLCT NELL1 ALKBH1 EHBP1L1 CSF1 GLG1 LRP4 AGAP9 AGAP7P AGAP4 AGAP6 NIPBL HCFC1

1.38e-0459311815MP:0005274
MousePhenoabnormal hearing electrophysiology

AGAP5 CDH23 REST PCYOX1L CSF1 CLCN1 OSBPL2 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6 KLHL18 NIPBL SLC4A11

1.40e-0459411815MP:0006335
MousePhenoabnormal monocyte cell number

SLC15A3 ITGB2 MEFV AGBL4 TMUB1 TRAP1 CSF1 CLCN1 PI4KA SNRNP200

1.97e-0429511810MP:0012441
MousePhenoabnormal ear physiology

AGAP5 CDH23 IREB2 REST PCYOX1L CSF1 CLCN1 OSBPL2 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6 KLHL18 NIPBL SLC4A11

2.00e-0468411816MP:0003878
MousePhenoabnormal uvea morphology

CYP1B1 AGAP5 NTRK1 ITGB2 ALKBH1 AGAP9 AGAP7P AGAP4 AGAP6

2.03e-042411189MP:0005197
MousePhenoabnormal iris morphology

CYP1B1 AGAP5 NTRK1 ALKBH1 AGAP9 AGAP7P AGAP4 AGAP6

2.21e-041921188MP:0001322
MousePhenoabnormal monocyte morphology

SLC15A3 ITGB2 MEFV AGBL4 TMUB1 TRAP1 CSF1 CLCN1 PI4KA SNRNP200

2.31e-0430111810MP:0002620
MousePhenodecreased bone ossification

ITGB2 NELL1 ALKBH1 NIPBL

2.57e-04371184MP:0020040
MousePhenoabnormal anterior uvea morphology

CYP1B1 AGAP5 NTRK1 ALKBH1 AGAP9 AGAP7P AGAP4 AGAP6

2.81e-041991188MP:0005194
MousePhenoimpaired liver regeneration

GFER FAH ABTB2

3.03e-04161183MP:0005517
MousePhenoabnormal snout morphology

AGAP5 ALKBH1 CSF1 AGAP9 AGAP7P AGAP4 AGAP6 NIPBL HCFC1

3.26e-042571189MP:0000443
MousePhenoabnormal hearing physiology

AGAP5 CDH23 REST PCYOX1L CSF1 CLCN1 OSBPL2 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6 KLHL18 NIPBL SLC4A11

3.30e-0464311815MP:0001963
MousePhenoabnormal tooth morphology

NCOA3 AGAP5 ALKBH1 EHBP1L1 CSF1 LRP4 AGAP9 AGAP7P AGAP4 AGAP6

3.58e-0431811810MP:0002100
MousePhenoabnormal dental arch morphology

NCOA3 AGAP5 ALKBH1 EHBP1L1 CSF1 LRP4 AGAP9 AGAP7P AGAP4 AGAP6

3.67e-0431911810MP:0030254
MousePhenocornea opacity

AGAP5 NTRK1 AGAP9 AGAP7P AGAP4 AGAP6 SLC4A11

3.96e-041591187MP:0001314
MousePhenoabnormal auditory brainstem response waveform shape

CSF1 OSBPL2 ATP2B2 NIPBL

4.22e-04421184MP:0011966
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.34e-06291415SM00105
DomainARFGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.34e-06291415PS50115
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.34e-06291415PF01412
DomainArfGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.34e-06291415IPR001164
DomainAnkyrin_rpt-contain_dom

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP9 AGAP7P AGAP4 AGAP6 ABTB2

2.35e-0525414110IPR020683
DomainANK_REP_REGION

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP9 AGAP7P AGAP4 AGAP6 ABTB2

2.35e-0525414110PS50297
DomainCl-channel_core

CLCN1 CLCN2 CLCN4

3.42e-0591413IPR014743
Domain-

CLCN1 CLCN2 CLCN4

3.42e-05914131.10.3080.10
DomainVoltage_CLC

CLCN1 CLCN2 CLCN4

3.42e-0591413PF00654
DomainCl-channel_volt-gated

CLCN1 CLCN2 CLCN4

3.42e-0591413IPR001807
DomainANK

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP7P AGAP4 AGAP6 ABTB2

1.24e-042511419SM00248
DomainANK_REPEAT

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP7P AGAP4 AGAP6 ABTB2

1.32e-042531419PS50088
DomainAnkyrin_rpt

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP7P AGAP4 AGAP6 ABTB2

1.71e-042621419IPR002110
DomainCBS_dom

CLCN1 CLCN2 CLCN4

4.37e-04201413IPR000644
DomainCBS

CLCN1 CLCN2 CLCN4

4.37e-04201413PF00571
DomainCBS

CLCN1 CLCN2 CLCN4

4.37e-04201413PS51371
Domain-

AGAP5 ILK ANKLE2 TRANK1 AGAP9 AGAP4 AGAP6 ABTB2

5.99e-0424814181.25.40.20
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.46e-109145512640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.91e-1010145520664521
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.32e-1011145515381706
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.47e-0913145527713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.28e-0914145522453919
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETD1A NES ILK RTCB ABCF2 MCM5 SNX33 PTBP1 ANKHD1 ALKBH1 KANSL1 SLC16A1 UBTF PI4KA XRN1 MMS19 MAPK1 PLOD1 SNRNP200 NIPBL TOP2A ZMYM3 EPB41L2

1.04e-0813531452329467282
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

AGAP5 PLPPR3 TRAP1 MYO1F CEP131 AGAP9 AGAP7P AGAP4 AGAP6 ARHGAP33

3.00e-082181451033378226
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1A AGAP5 ANKHD1 ANKLE2 RUFY3 UBE2O TRANK1 LRP4 HHIPL1 AGAP9 AGAP7P AGAP4 AGAP6

3.75e-075291451314621295
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

AGAP5 PLPPR3 YES1 PI4KA CPNE4 AGAP9 AGAP7P AGAP4 ATP2B2 AGAP6 FAM131B

1.17e-064051451138187761
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

MCM5 PTBP1 RNF2 HTATSF1 MMS19 MAPK1 HCFC1

1.24e-06129145723022380
Pubmed

Expression of CLCN voltage-gated chloride channel genes in human blood vessels.

CLCN1 CLCN2 CLCN4

1.41e-066145310198195
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

TCAF1 RTCB RBM3 NOA1 MCM5 REST PTBP1 YES1 BLK TRAP1 UBE2O RNF2 UBTF HTATSF1 MAPK1 POLQ SNRNP200 HCFC1

1.62e-0611531451829845934
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TPT1 MYH13 SIK1 ABCF2 MCM5 APOB ACTN3 PTBP1 NEB ANKLE2 TRAP1 RNF2 CLCN4 XRN1 SEPTIN10 POLQ ATP2B2 NIPBL TOP2A SLC4A11

2.49e-0614421452035575683
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

AGAP5 REST MED13L RNF2 KANSL1 ARID2 AGAP9 AGAP7P AGAP4 AGAP6 NIPBL EPB41L2

2.81e-065361451215840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

AGAP5 REST MED13L RNF2 KANSL1 ARID2 AGAP9 AGAP7P AGAP4 AGAP6 NIPBL EPB41L2

2.92e-065381451210512203
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TPT1 NCOA3 ILK RTCB RBM3 GPS2 MCM5 MED13L PTBP1 UBTF ARID2 MAPK1 SNRNP200 NIPBL HCFC1 TOP2A ZMYM3

3.81e-0611031451734189442
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NES RTCB MCM5 ANKHD1 UBE2O UBTF XRN1 PLOD1 SNRNP200 NIPBL HCFC1 ZMYM3 EPB41L2

3.84e-066531451322586326
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA3 RTCB MCM5 PTBP1 UBTF ARID2 SNRNP200 HCFC1

4.28e-06220145835785414
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

NES ATP6V1E1 RTCB MCM5 YES1 UBTF PI4KA SSH2 SEPTIN10 PLOD1 SNRNP200 TOP2A EPB41L2

4.31e-066601451332780723
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

SETD1A AGAP5 CDH23 LAMC3 EHBP1L1 RPIA GLG1 ARID2 MAPK1 AGAP9 AGAP7P SEPTIN10 AGAP4 ATP2B2 AGAP6 KLHL18 ABTB2 PLXNB3

4.55e-0612421451830973865
Pubmed

Changing expression of chloride channels during preimplantation mouse development.

CLCN1 CLCN2 CLCN4

5.85e-069145323115349
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

TCAF1 ABCF2 RYR3 SLC16A1 UBTF MMS19 SNRNP200 TOP2A

6.12e-06231145836597993
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NES RTCB ABCF2 MCM5 PTBP1 YES1 TRAP1 UBTF PI4KA CEP131 MAPK1 PLOD1 SNRNP200 NIPBL TOP2A EPB41L2

6.32e-0610241451624711643
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

TCAF1 ILK RTCB RBM3 ABCF2 MCM5 PTBP1 ANKHD1 UBE2O SLC16A1 GLG1 HTATSF1 MAPK1 PLOD1 SNRNP200 NIPBL HCFC1 TOP2A EPB41L2

7.21e-0614151451928515276
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

MYH13 NEB RYR3 RPIA TRANK1 UBTF ARID2 C4B ADGRF3 PLOD1 HCFC1

8.24e-064971451136774506
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

MYOM1 ACTN3 NEB

8.34e-0610145320368620
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NES ATP6V1E1 PDE2A RTCB ACTN3 PTBP1 TF RUFY3 AGBL4 UBE2O PI4KA XRN1 C4B SSH2 MAPK1 CPNE4 ATP2B2 SNRNP200 EPB41L2

8.44e-0614311451937142655
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

AGAP5 MCM5 APOB NEB TRAP1 XRN1 AGAP7P AGAP4 SNRNP200 KLHL18 HCFC1

1.11e-055131451125798074
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

ILK PTBP1 ARID2 MMS19 SNRNP200 NIPBL HCFC1 TOP2A ZMYM3

1.15e-05332145932786267
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

MYOM1 ACTN3 NEB

1.52e-051214538618961
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYP1B1 RTCB RBM3 NOA1 ABCF2 MCM5 EXOSC5 ANKHD1 YES1 RNF2 GLG1 PI4KA ARID2 XRN1 CDC42EP5 CEP131 NIPBL ZMYM3 EPB41L2

1.58e-0514971451931527615
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

ILK RTCB ABCF2 MCM5 PTBP1 ANKHD1 AKR7A2 TMUB1 TRAP1 XRN1 EPB41L2

1.60e-055341451135032548
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A NR2F6 PDE2A POMGNT1 MCM5 LAMC3 MED13L ANKHD1 EHBP1L1 KANSL1 PI4KA LRP4 CEP131 HCFC1 ABTB2 ARHGAP33

1.62e-0511051451635748872
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

TPT1 NES ATP6V1E1 TCAF1 ILK RTCB CALML3 MCM5 YES1 REXO2 UBE2O SLC16A1 GLG1 HTATSF1 MAPK1 PLOD1 HCFC1 TOP2A

1.66e-0513671451832687490
Pubmed

Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin.

NEB RBM20

1.73e-052145227139341
Pubmed

Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice.

CDH23 ATP2B2

1.73e-052145211423214
Pubmed

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities.

ITGB2 PCYOX1L

1.73e-052145237179332
Pubmed

Modification of human hearing loss by plasma-membrane calcium pump PMCA2.

CDH23 ATP2B2

1.73e-052145215829536
Pubmed

Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation.

MAPK1 TOP2A

1.73e-052145210207078
Pubmed

A genetic variant near the PMAIP1/Noxa gene is associated with increased bleomycin sensitivity.

NOA1 REST

1.73e-052145221106707
Pubmed

ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.

MAPK1 TOP2A

1.73e-052145238097570
Pubmed

The Emerging Role of the RBM20 and PTBP1 Ribonucleoproteins in Heart Development and Cardiovascular Diseases.

PTBP1 RBM20

1.73e-052145232276354
Pubmed

In vivo suppressor mutations correct a murine model of hereditary tyrosinemia type I.

HGD FAH

1.73e-052145210518553
Pubmed

mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw).

CDH23 ATP2B2

1.73e-05214529325047
Pubmed

A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers.

CDH23 ATP2B2

1.73e-052145223792079
Pubmed

Ribotoxic stress through p38 mitogen-activated protein kinase activates in vitro the human pyrin inflammasome.

MEFV MAPK1

1.73e-052145223479736
Pubmed

Down-regulation of salt-inducible kinase 1 (SIK1) is mediated by RNF2 in hepatocarcinogenesis.

SIK1 RNF2

1.73e-052145227911266
Pubmed

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness.

CDH23 ATP2B2

1.73e-052145217234811
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

TPT1 RBM3 MCM5 APOB PTBP1 TF RPIA C4B SNRNP200 NIPBL HCFC1 TOP2A

2.00e-056521451231180492
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A RTCB ANKHD1 UBE2O RNF2 SLC16A1 ARID2 XRN1 SNRNP200 HCFC1 TOP2A

2.07e-055491451138280479
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PLPPR3 PTBP1 ANKLE2 RUFY3 AKR7A2 TRAP1 UBE2O SLC16A1 GLG1 PI4KA XRN1 CEP131 CPNE4 SEPTIN10 FAM131B EPB41L2

2.34e-0511391451636417873
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

HGD ATP6V1E1 MAN1A1 MYH13 CALML3 NEB TF SLC22A12 AKR7A2 FAH SIAE GK2 GLG1 PLOD1 NIPBL

2.42e-0510161451519056867
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

ATP6V1E1 ILK RTCB ABCF2 MCM5 ACTN3 TRAP1 SLC16A1 MAPK1 SNRNP200 HCFC1 TOP2A

2.42e-056651451230457570
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

AGAP5 PI4KA MAPK1 AGAP9 AGAP7P AGAP4 AGAP6 EPB41L2

2.52e-05281145828706196
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RTCB ABCF2 MCM5 LAMC3 APOB PTBP1 ANKHD1 TRAP1 UBE2O RNF2 SLC16A1 UBTF PI4KA SNRNP200 NIPBL HCFC1 TOP2A EPB41L2

2.87e-0514251451830948266
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

TCAF1 ABCF2 MCM5 EXOSC5 ANKHD1 UBE2O OSBPL2 RNF2 SLC16A1 PI4KA MAPK1

2.96e-055711451137167062
Pubmed

Defining the membrane proteome of NK cells.

MAN1A1 ILK ABCF2 MCM5 PTBP1 ANKLE2 ITGB2 PCYOX1L TRAP1 EHBP1L1 SLC16A1 GLG1 PI4KA XRN1 MMS19 HCFC1

3.16e-0511681451619946888
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

CYP1B1 B3GLCT RTCB NOA1 POMGNT1 ABCF2 MCM5 SNX33 ANKLE2 AKR7A2 TRAP1 RPIA GLG1 HTATSF1 MAPK1 PLOD1 SNRNP200 EPB41L2

3.63e-0514511451830550785
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

RUFY3 CLCN4 PI4KA ATP2B2 NIPBL

3.89e-0590145515033168
Pubmed

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.

RTCB ABCF2 PTBP1 UBTF HTATSF1 SNRNP200 TOP2A

4.06e-05220145734091597
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

RNF2 KANSL1 HTATSF1 NIPBL HCFC1 ZMYM3

4.13e-05150145628242625
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

APOB ITGB2 TF CFAP54 C4B

4.32e-0592145537343697
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

RTCB ABCF2 MCM5 APOB MEFV UBE2O SLC16A1 UBTF SNRNP200 EPB41L2

4.33e-054911451036273042
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

TPT1 AGAP5 KANSL1 AGAP7P AGAP4 SNRNP200 EPB41L2

4.68e-05225145725277244
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

NES TCAF1 ILK MCM5 PTBP1 YES1 RUFY3 XRN1 HCFC1 TOP2A

4.88e-054981451036634849
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

RTCB UGT1A6 ABCF2 MCM5 TF SLC16A1 HTATSF1 MAPK1 SNRNP200 TOP2A EPB41L2

5.14e-056071451139147351
Pubmed

Aneuploidy as a mechanism for stress-induced liver adaptation.

HGD FAH

5.16e-053145222863619
Pubmed

RNA-binding proteins RBM20 and PTBP1 regulate the alternative splicing of FHOD3.

PTBP1 RBM20

5.16e-053145230468920
Pubmed

Plasma concentrations of apolipoproteins A-I, B, and M in patients with critical limb ischemia.

APOB APOM

5.16e-053145220080084
Pubmed

Plasma concentrations of apolipoproteins A-I, B and M in patients with abdominal aortic aneurysms.

APOB APOM

5.16e-053145219932694
Pubmed

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF.

UBTF MAPK1

5.16e-053145211741541
Pubmed

G protein pathway suppressor 2 enhanced the renal large-conductance Ca2+-activated potassium channel expression via inhibiting ERK1/2 signaling pathway.

GPS2 MAPK1

5.16e-053145229767559
Pubmed

Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization.

CSF1 SCGB1A1

5.16e-053145230054206
Pubmed

The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection.

SETD1A HCFC1

5.16e-053145217578910
Pubmed

Modulation of cell adhesion and motility in the immune system by Myo1f.

ITGB2 MYO1F

5.16e-053145217023661
Pubmed

Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4.

PTBP1 RBM20

5.16e-053145229518215
Pubmed

MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1.

SETD1A HCFC1

5.16e-053145233050986
Pubmed

Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation.

NES MAPK1

5.16e-053145227894083
Pubmed

Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.

NEB RBM20

5.16e-053145227889803
Pubmed

Induction of dendritic cell-like phenotype in macrophages during foam cell formation.

APOB CSF1

5.16e-053145217244792
Pubmed

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor.

NCOA3 MAPK1

5.16e-053145210866661
Pubmed

Phosphorylation of MCT-1 by p44/42 MAPK is required for its stabilization in response to DNA damage.

SLC16A1 MAPK1

5.16e-053145217016429
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

SETD1A CALML3 MCM5 RNF2 PI4KA MMS19 SNRNP200 NIPBL HCFC1

5.96e-05410145926949251
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

TPT1 ATP6V1E1 RTCB EXOSC5 MED13L ANKHD1 YES1 TF TRAP1 UBTF PI4KA XRN1

6.10e-057321451234732716
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

TCAF1 MYH13 RTCB RBM3 IREB2 APOB SNX33 ACTN3 PTBP1 ANKHD1 TRAP1 RNF2 C4B CEP131 PLOD1 HCFC1 EPB41L2

6.11e-0513711451736244648
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TCAF1 OSBPL2 SNRNP200 KLHL18 FAM131B

6.75e-0510114559872452
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

TPT1 RTCB MCM5 ANKHD1 UBE2O PI4KA SEPTIN10 ATP2B2 SNRNP200 TOP2A

9.23e-055381451028524877
Pubmed

Human transcription factor protein interaction networks.

NCOA3 SETD1A RTCB GPS2 ANKHD1 RBM20 PRDM1 UBE2O RNF2 KANSL1 UBTF ARID2 XRN1 CEP131 NIPBL HCFC1 ZMYM3

1.01e-0414291451735140242
Pubmed

Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B.

ILK MAPK1

1.03e-044145221177334
Pubmed

The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles.

APOB APOM

1.03e-044145222826357
Pubmed

Lycium barbarum Polysaccharides Promote Maturity of Murine Dendritic Cells through Toll-Like Receptor 4-Erk1/2-Blimp1 Signaling Pathway.

PRDM1 MAPK1

1.03e-044145233344654
Pubmed

An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2.

ILK MAPK1

1.03e-044145225398317
Pubmed

Nestin is expressed during development and in myotendinous and neuromuscular junctions in wild type and desmin knock-out mice.

NES MYOM1

1.03e-044145210438587
Pubmed

B cell receptor-ERK1/2 signal cancels PAX5-dependent repression of BLIMP1 through PAX5 phosphorylation: a mechanism of antigen-triggering plasma cell differentiation.

PRDM1 MAPK1

1.03e-044145222593617
Pubmed

Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration.

NTRK1 RUFY3

1.03e-044145231221560
Pubmed

Alternative Splicing of Cdh23 Exon 68 Is Regulated by RBM24, RBM38, and PTBP1.

CDH23 PTBP1

1.03e-044145232774357
Pubmed

Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1.

TRAP1 MAPK1

1.03e-044145228099845
Pubmed

Neurotrophin receptors TrkA and TrkB in retinoblastoma are differentially expressed depending on cellular differentiation.

NTRK1 MAPK1

1.03e-044145219816090
Pubmed

MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly.

APOB MAPK1

1.03e-044145217038630
Pubmed

GM-CSF regulates fusion of mononuclear osteoclasts into bone-resorbing osteoclasts by activating the Ras/ERK pathway.

CSF1 MAPK1

1.03e-044145219641137
InteractionRSPH6A interactions

TCAF1 MYH13 RSPH6A ACTN3 NEB

3.95e-06341435int:RSPH6A
InteractionSNRPN interactions

NTRK1 REST ACVRL1 YES1 UBE2O RNF2 HTATSF1 SNRNP200 HCFC1

7.38e-061861439int:SNRPN
InteractionTTN interactions

MYOM1 RBM3 NTRK1 RSPH6A ACTN3 NEB SLC15A3 RNF2 MAPK1 ABTB2 TOP2A

9.72e-0629914311int:TTN
GeneFamilyAnkyrin repeat domain containing

AGAP5 ILK ANKHD1 ANKLE2 TRANK1 AGAP9 AGAP7P AGAP4 AGAP6 ABTB2

8.42e-072429910403
GeneFamilyArfGAPs

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

9.34e-0733995395
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP5 AGAP9 AGAP4 AGAP6

1.91e-06179941291
GeneFamilyChloride voltage-gated channels

CLCN1 CLCN2 CLCN4

1.86e-0510993302
GeneFamilyRNA binding motif containing

SETD1A ENOX1 RBM3 PTBP1 RBM20 HTATSF1

1.12e-03213996725
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.77e-06371445MM1121
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

4.27e-06441445MM485
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_UP

CYP1B1 REST SLC15A3 ITGB2 CSF1 SLC16A1 EPB41L2

3.97e-051671447M2395
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

TPT1 NCOA3 MAN1A1 REST ANKLE2 ITGB2 PRDM1 TRANK1 CSF1 KANSL1 GLG1 UBTF ARID2 SLC7A5P2 MYO1F XRN1 IL17RA SSH2 MAPK1 SNRNP200 NIPBL

6.78e-05149214421M40023
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_UP

CYP1B1 REST SLC15A3 ITGB2 CSF1 SLC16A1 EPB41L2

7.59e-051851447MM1072
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D

TPT1 TCAF1 ENOX1 SNX33 PTBP1 TST GFER SLC22A12 FAH EHBP1L1 CLCN2 PLOD1 NIPBL HCFC1 EPB41L2

8.69e-0586514415M2417
CoexpressionWIERENGA_STAT5A_TARGETS_DN

HGD ILK PCYOX1L CLCN2 CLCN4 PLXDC2 IL17RA

9.88e-051931447M2213
CoexpressionAFFAR_YY1_TARGETS_DN

SETD1A ATP6V1E1 MCM5 REST GK2 CLCN1 PCOLCE2 TOP2A

9.91e-052601448M1471
CoexpressionLU_AGING_BRAIN_UP

CYP1B1 TCAF1 TST YES1 SLC16A1 LRP4 SEPTIN10 NIPBL

1.07e-042631448M5547
CoexpressionBENPORATH_NANOG_TARGETS

CYP1B1 TCAF1 MAN2C1 ABCF2 APOB EXOSC5 REST RYR3 APOM ALKBH1 RNF2 GLG1 SLC7A5P2 KLHL18 TOP2A FAM131B

1.11e-0498814416M6616
CoexpressionGSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP

NR2F6 MAN1A1 TST CLCN4 MYO1F IL17RA ARHGAP33

1.12e-041971447M5363
CoexpressionMULLIGHAN_MLL_SIGNATURE_2_UP

GPS2 RSPH6A ITGB2 AKR7A2 EHBP1L1 GLG1 MYO1F IL17RA PLOD1 NIPBL

1.14e-0442014410M3053
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D

TPT1 TCAF1 ENOX1 SNX33 PTBP1 TST GFER SLC22A12 FAH EHBP1L1 CLCN2 PLOD1 NIPBL HCFC1 EPB41L2

1.16e-0488814415MM1315
CoexpressionGSE40666_WT_VS_STAT4_KO_CD8_TCELL_DN

B3GLCT ILK NOA1 REXO2 ACAD8 GLG1 PI4KA

1.20e-041991447M9223
CoexpressionGSE14308_TH1_VS_NAIVE_CD4_TCELL_DN

NCOA3 SETD1A GPS2 IREB2 MED13L SNRNP200 ZMYM3

1.23e-042001447M3377
CoexpressionGSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN

RBM3 YES1 TF PRDM1 KANSL1 GLG1 IL17RA

1.23e-042001447M3893
CoexpressionGSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

SNX33 NEB SLC15A3 EHBP1L1 MYO1F PCOLCE2 TOP2A

1.23e-042001447M7962
CoexpressionGSE3982_DC_VS_BASOPHIL_UP

LAMC3 TST ATP10A GLG1 SCGB1A1 PCOLCE2 POLQ

1.23e-042001447M5472
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPT1 NTRK1 CSF1 PLXDC2 SCARA5 C4B PCOLCE2 EPB41L2

1.78e-0718714487beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCelldroplet-Kidney-nan-21m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD CDH23 APOB SLC22A12 AKR7A2 APOM FAH

2.26e-06183144701e7256c9e0ce53f8e10f3d3a5be15dedd312426
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP1B1 NTRK1 RBM20 PLXDC2 SCARA5 C4B PCOLCE2

2.51e-0618614477c1807fca590cdccf7f5734460bac228d33964ca
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCAF1 YES1 RUFY3 NELL1 KANSL1 ARID2 XRN1

2.70e-0618814476468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCAF1 YES1 RUFY3 NELL1 KANSL1 ARID2 XRN1

2.70e-0618814477a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCAF1 YES1 RUFY3 NELL1 KANSL1 ARID2 XRN1

2.70e-0618814479cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPT1 CALML3 TST SLC22A12 AKR7A2 APOM FAH

3.21e-06193144755f37fdba469bea9869a34c4d4f00cb1a3b7a73f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP1B1 RBM3 ITGB2 MEFV SCGB1A1 MYO1F IL17RA

3.43e-061951447f8908657db50f1c58904dd6fee4fc23f5ae3eed6
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

MGAM MEFV EHBP1L1 PLXDC2 MYO1F IL17RA SSH2

3.67e-061971447a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellsevere-unassigned|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NEB TF CLCN4 POLQ TOP2A ARHGAP33

3.81e-061281446bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCelldroplet-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 ITGB2 EHBP1L1 SCGB1A1 MYO1F IL17RA

9.85e-061511446c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BLK SIAE ZNF547 CLCN2 ARID2 ZNF697

1.02e-051521446b8aa62e3cf2b4c252db4bccfa75d881c4fa0a788
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ENOX1 RSPH6A GFER PLXDC2 MYO1F PCOLCE2

1.10e-05154144644d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NR2F6 ITGB2 MEFV EHBP1L1 MYO1F IL17RA

1.27e-051581446b35bab2b93d0af821bfae18a358eb7dddaf3860f
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NR2F6 ITGB2 MEFV EHBP1L1 MYO1F IL17RA

1.27e-0515814467bd4a64a610eb1cbcd3d07ea5258a55107cf6c00
ToppCellmild-Myeloid-Eosinophils|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NTRK1 RYR3 CSF1 TEX101 SSH2 ABTB2

1.52e-0516314467c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD TST SLC22A12 AKR7A2 APOM FAH

1.63e-051651446082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD TST SLC22A12 AKR7A2 APOM FAH

1.69e-0516614460868f45d8d39ad39b5cee5e81ac3dd4dc512775d
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CALML3 LAMC3 REXO2 LRP4 C4B PCOLCE2

1.80e-051681446d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 SIK1 ITGB2 MYO1F IL17RA SSH2

1.87e-051691446ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 SIK1 ITGB2 MYO1F IL17RA SSH2

1.87e-051691446c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPT1 MYOM1 RYR3 TRANK1 C4B ATP2B2

1.87e-05169144612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 SIK1 ITGB2 SCGB1A1 MYO1F IL17RA

2.06e-05172144651bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 SIK1 ITGB2 SCGB1A1 MYO1F IL17RA

2.06e-051721446be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP1B1 ATP10A MEFV PLXDC2 MYO1F HHIPL1

2.58e-051791446cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

2.66e-051801446b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

2.75e-051811446bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

2.75e-051811446cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NTRK1 NELL1 CSF1 CEP131 ADGRF3 ATP2B2

2.83e-0518214464cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TPT1 ITGB2 PLXDC2 MYO1F IL17RA EPB41L2

2.83e-051821446c6b3762ccec326f057819f75fa7fac0145fb7d54
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 ENOX1 PLXDC2 SCARA5 C4B PCOLCE2

2.92e-051831446a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCelldroplet-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 ENOX1 PLXDC2 SCARA5 C4B PCOLCE2

2.92e-051831446ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

NCOA3 MAN1A1 PRDM1 BLK POLQ ACOXL

2.92e-0518314462c016bb59f131a0e821853b085289a3583f0a729
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

3.01e-0518414463d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

3.01e-05184144645577ff91c3b2b303acd97239dde2463ea7a429c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 ATP6V1E1 SLC15A3 ITGB2 RPIA IL17RA

3.01e-0518414468e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

3.10e-0518514463e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB SLC22A12 AKR7A2 APOM FAH

3.10e-0518514460ff4148b4701003d9d594e0da8261176fb13aa59
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP1B1 MGAM CSF1 SCARA5 PCOLCE2 CPNE4

3.10e-051851446d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 CDH23 TRANK1 SCARA5 PCOLCE2 EPB41L2

3.40e-051881446ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 CDH23 TRANK1 SCARA5 PCOLCE2 EPB41L2

3.60e-051901446efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellHSPCs-Gran/Mono_prog.|World / Lineage and Cell class

PLPPR3 MCM5 EXOSC5 PCYOX1L TRAP1 MYO1F

3.60e-05190144694547c1cc2c3f2ac28a6d07317e50e1e3fd20267
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAN1A1 LHFPL3 PRDM1 CDC42EP5 ABTB2

3.62e-051151445ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC15A3 ITGB2 EHBP1L1 PLXDC2 MYO1F EPB41L2

3.71e-051911446b5715eeb72a97b7bc87b83f6c289e225f58da842
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP1B1 NTRK1 PLXDC2 SCARA5 C4B PCOLCE2

3.71e-0519114462b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

MAN1A1 PLXDC2 SCARA5 PCOLCE2 ABTB2 EPB41L2

3.82e-051921446356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellMacrophages-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SLC15A3 ITGB2 ATP10A CSF1 PLXDC2 PCOLCE2

3.93e-051931446a6694b33adcdb17cdd1567eb9507dbf06e6468d8
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

MAN1A1 PLXDC2 SCARA5 PCOLCE2 SSH2 ABTB2

4.05e-05194144611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellnormal_Lung|World / Location, Cell class and cell subclass

MAN1A1 ACVRL1 SLC15A3 PLXDC2 SCGB1A1 PCOLCE2

4.05e-051941446affae83d7f982d18117f5b95705f09809f304b0b
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP10A PLXDC2 SLC16A1 IL17RA NIPBL ABTB2

4.05e-051941446f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP10A PLXDC2 SLC16A1 IL17RA NIPBL ABTB2

4.05e-051941446cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP10A PLXDC2 SLC16A1 IL17RA NIPBL ABTB2

4.05e-05194144666c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGD TPT1 TST AKR7A2 APOM FAH

4.16e-051951446eb96439b59914954f684c4bfd9e9a6dbd3201a20
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP10A PLXDC2 SLC16A1 IL17RA NIPBL ABTB2

4.16e-05195144679114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

MAN1A1 PLXDC2 SCARA5 SSH2 ABTB2 EPB41L2

4.16e-051951446ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH23 ITGB2 MEFV EHBP1L1 MYO1F SSH2

4.16e-0519514461d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

MGAM MEFV PLXDC2 MYO1F IL17RA SSH2

4.28e-05196144604d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

CDH23 ITGB2 EHBP1L1 PLXDC2 MYO1F IL17RA

4.28e-0519614463ef193c5180de3137daf886492e74fc574bc9767
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NEB TF CLCN4 POLQ TOP2A ARHGAP33

4.41e-05197144670704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell(5)_Fibroblasts-(5)_Fibroblast-F|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CYP1B1 RBM3 ACVRL1 REXO2 SCARA5 PCOLCE2

4.41e-051971446fbff2fb7a8142b88c9dc71aa10980f4350b7e081
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEFV EHBP1L1 PLXDC2 MYO1F IL17RA SSH2

4.53e-051981446ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HGD ABCF2 RYR3 CSF1 PLOD1 PLXNB3

4.53e-051981446399760b6b6fef8639ded53b14f251b9fce600e81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGD TPT1 CALML3 TST SLC22A12 APOM

4.53e-051981446a9d72b17adfddb6ac1857c5f094280e86582693b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGD TPT1 CALML3 TST SLC22A12 APOM

4.53e-051981446b933bd66f544822fcf1f2aa2d928c31500e2b3f4
ToppCellCOVID-19-kidney-PCT-S3-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGD CALML3 GPS2 TST SLC22A12 AKR7A2

4.53e-05198144636a60397f49f5381ae377155b73e1891448846b7
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

CYP1B1 ITGB2 MEFV PLXDC2 MYO1F IL17RA

4.79e-052001446621af09aae34226902c03edf556562f3ab35a7d8
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

CYP1B1 ITGB2 MEFV PLXDC2 MYO1F IL17RA

4.79e-052001446b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MGAM SLC15A3 ITGB2 MEFV CSF1 MYO1F

4.79e-052001446fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCellcontrol-Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYP1B1 MED13L SLC15A3 MEFV PLXDC2 IL17RA

4.79e-052001446b5d197472799cc61d7497faed91ac2564ae4930a
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

CYP1B1 ITGB2 MEFV PLXDC2 MYO1F IL17RA

4.79e-052001446e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellParenchyma_Control_(B.)|World / Sample group, Lineage and Cell type

MAN1A1 SLC15A3 ATP10A PLXDC2 SCARA5 PCOLCE2

4.79e-052001446220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM CALML3 TST SLC22A12 APOM FAH

4.79e-052001446825aad08431dd6b54aa636ace6efc821dfaf8014
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLPPR3 LAMC3 NELL1 LRP4 ADGRF3

1.24e-041491445aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM5 RSPH6A BLK RPIA SLC4A11

1.28e-041501445d6b977dd47aa017f6ba762f0c505cd896caa523f
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB TST APOM FAH

1.32e-0415114457758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB TST APOM FAH

1.32e-041511445b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

NTRK1 CFAP54 CSF1 LRP4 ATP2B2

1.36e-041521445519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB TST APOM FAH

1.36e-041521445faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

NTRK1 CFAP54 CSF1 LRP4 ATP2B2

1.36e-041521445faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB TST APOM FAH

1.36e-0415214451febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 ITGB2 SCGB1A1 MYO1F IL17RA

1.40e-0415314456dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 ITGB2 SCGB1A1 MYO1F IL17RA

1.40e-041531445f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TF SCGB1A1 BPIFB4 CDC42EP5 CPNE4

1.49e-0415514458dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TF SCGB1A1 BPIFB4 CDC42EP5 CPNE4

1.49e-04155144542533beaded07068f00540de704de07e4f19abcf
ToppCellPND07-28-samps-Myeloid-Granulocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SIK1 ITGB2 MEFV MYO1F IL17RA

1.53e-0415614455e1c5a7c9293b886920739cf766521df7f69726c
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 EHBP1L1 ADGRF3 ATP2B2 TOP2A

1.53e-0415614458349604bd801e20d33770f7d8243598c3756302b
ToppCellPND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SIK1 ITGB2 MEFV MYO1F IL17RA

1.53e-041561445166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCellfacs-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 ITGB2 MEFV MYO1F IL17RA

1.53e-0415614453f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCellfacs-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 ITGB2 MEFV MYO1F IL17RA

1.53e-04156144569e6e8810d1738a66c9821910f41498931cf30cc
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC15A3 MEFV CSF1 IL17RA ABTB2

1.58e-0415714455098675f64342c41c5ca3551b24962d10c83e64d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTRK1 LAMC3 ATP10A PLXDC2 SCARA5

1.58e-0415714451e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCellfacs-Lung-Endomucin_-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC15A3 ITGB2 MEFV MYO1F IL17RA

1.58e-0415714452b60de520edf167f5ca790b478557a778435b3d9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10A SLC22A12 RYR3 NELL1 PCOLCE2

1.68e-041591445fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10A SLC22A12 RYR3 NELL1 PCOLCE2

1.68e-041591445aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10A SLC22A12 RYR3 NELL1 PCOLCE2

1.68e-0415914458bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

PDE2A MYOM1 RYR3 SCARA5 PCOLCE2

1.73e-0416014458a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

PDE2A MYOM1 RYR3 SCARA5 PCOLCE2

1.73e-041601445c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC15A3 ITGB2 MEFV PRDM1 MYO1F

1.73e-0416014456329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

PDE2A MYOM1 RYR3 SCARA5 PCOLCE2

1.73e-041601445d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD APOB APOM FAH C4B

1.78e-041611445274838cebdc7af1db32d309dfe42ef7ccd3c190b
DrugAC1L1K7T

CYP1B1 NCOA3 NR2F6 CALML3 NTRK1 UGT1A6 SIK1 ACVRL1 TF PRDM1 CSF1 CLCN1 CLCN2 OSBPL2 CLCN4 MAPK1

2.41e-0663214316CID000005376
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; PC3; HT_HG-U133A

MGAM PDE2A APOB RSPH6A ATP10A GFER CSF1 CLCN4 SCGB1A1

4.63e-0619814394101_UP
Diseasecerebral palsy (implicated_via_orthology)

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.53e-10101405DOID:1969 (implicated_via_orthology)
DiseaseDeafness, Autosomal Recessive 12

CDH23 ATP2B2

2.24e-0521402C1832394
DiseaseAutosomal recessive nonsyndromic hearing loss 12

CDH23 ATP2B2

2.24e-0521402cv:C1832394
Diseaseautosomal recessive nonsyndromic deafness 12 (is_implicated_in)

CDH23 ATP2B2

2.24e-0521402DOID:0110467 (is_implicated_in)
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE 12

CDH23 ATP2B2

2.24e-0521402601386
Diseasecancer (implicated_via_orthology)

CALML3 YES1 ITGB2 BLK RNF2 MAPK1 NIPBL TOP2A

4.43e-052681408DOID:162 (implicated_via_orthology)
DiseaseBehcet Syndrome

APOB ITGB2 MEFV

1.97e-04241403C0004943
Diseasecolorectal cancer (implicated_via_orthology)

SNX33 YES1 BLK

3.86e-04301403DOID:9256 (implicated_via_orthology)
Diseaseanemia (biomarker_via_orthology)

IREB2 TF

4.62e-0471402DOID:2355 (biomarker_via_orthology)
Diseaseosteopetrosis (implicated_via_orthology)

CSF1 CLCN4

4.62e-0471402DOID:13533 (implicated_via_orthology)
Diseasefrontotemporal dementia

ACTN3 CFAP54 CEP131

4.69e-04321403MONDO_0017276
Diseasemonocyte percentage of leukocytes

CDH23 MED13L TRAP1 CSF1 KANSL1 GLG1 PI4KA MYO1F IL17RA SSH2 ACOXL

7.55e-0473114011EFO_0007989
DiseaseFEV/FEC ratio

CYP1B1 MGAM ENOX1 CDH23 IREB2 RSPH6A SNX33 REST NEB AGBL4 CLCN4 PLXDC2 MYO1F HHIPL1 SSH2

7.55e-04122814015EFO_0004713
DiseaseDisease Exacerbation

ABCF2 EXOSC5 TRAP1 ACAD8 TOP2A

1.17e-031651405C0235874
Diseasemyotonia congenita (implicated_via_orthology)

MYH13 CLCN1

1.43e-03121402DOID:2106 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH13 CLCN1 CLCN2

1.55e-03481403DOID:423 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

CYP1B1 NCOA3 NR2F6 PDE2A MAN2C1 RBM3 NOA1 CSF1 CLCN1 ZNF436 PLOD1 NIPBL TOP2A

1.85e-03107414013C0006142
DiseaseNephrosis

NES ITGB2

2.25e-03151402C0027720
Diseaseresponse to statin, LDL cholesterol change measurement

APOB EPB41L2

2.25e-03151402EFO_0007804, GO_0036273
Diseaseanemia (implicated_via_orthology)

IREB2 SLC4A11

2.25e-03151402DOID:2355 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

FADS2B RYR3 ARID2 ADGRF3 SSH2

2.43e-031951405DOID:1574 (implicated_via_orthology)
DiseaseN-acetyl-beta-alanine measurement

RYR3 VPS35L

2.57e-03161402EFO_0021430
Diseasecathepsin L1 measurement

SLC15A3 PLXDC2

2.57e-03161402EFO_0010619
Diseaseurate measurement, spine bone mineral density

UGT1A6 RBM20 CPNE4

2.67e-03581403EFO_0004531, EFO_0007701
Diseasewhite matter microstructure measurement

MAN1A1 APOB ANKHD1 ITGB2 TF KANSL1 SSH2

2.67e-033901407EFO_0005674
Diseaseacute kidney failure (biomarker_via_orthology)

NES GFER SCGB1A1

3.08e-03611403DOID:3021 (biomarker_via_orthology)
DiseaseC-X-C motif chemokine 16 measurement

CDH23 ACOXL

3.25e-03181402EFO_0010911
Diseaseserum hepcidin measurement

TF NELL1

3.25e-03181402EFO_0004504
Diseaseglomerulonephritis (is_marker_for)

TF CSF1

3.63e-03191402DOID:2921 (is_marker_for)
DiseaseMammary Carcinoma, Human

CYP1B1 NCOA3 NR2F6 PDE2A MAN2C1 RBM3 CSF1 TOP2A

3.68e-035251408C4704874
DiseaseMammary Neoplasms, Human

CYP1B1 NCOA3 NR2F6 PDE2A MAN2C1 RBM3 CSF1 TOP2A

3.68e-035251408C1257931
DiseaseMammary Neoplasms

CYP1B1 NCOA3 NR2F6 PDE2A MAN2C1 RBM3 CSF1 TOP2A

3.76e-035271408C1458155
DiseaseBreast Carcinoma

CYP1B1 NCOA3 NR2F6 PDE2A MAN2C1 RBM3 CSF1 TOP2A

4.25e-035381408C0678222
Diseasetransferrin glycosylation measurement

TF REXO2

4.42e-03211402EFO_0021537
DiseaseMalignant Glioma

NTRK1 CLCN2 TOP2A

4.54e-03701403C0555198
Diseasemixed gliomas

NTRK1 CLCN2 TOP2A

4.54e-03701403C0259783
Diseaseage-related hearing impairment

ENOX1 CDH23 SIK1 SNX33 MED13L SLC4A11

4.60e-033241406EFO_0005782
DiseaseLupus Erythematosus, Systemic

PRDM1 BLK C4B

4.72e-03711403C0024141

Protein segments in the cluster

PeptideGeneStartEntry
AGDRMAGAPMAAAVQ

AGAP4

36

Q96P64
ADAINEFEGGMMLVS

ABCF2

556

Q9UG63
MAGDRAFSQGEVIMD

ADGRF3

691

Q8IZF5
VDNIVFNMAAGSAPM

APOM

66

O95445
AAPASGEMTMDALLA

ANKLE2

56

Q86XL3
EMGRRMDAPASAAAV

AKR7A2

46

O43488
LIMSNIGADGMLDFP

CFAP54

451

Q96N23
GDRGVMMDISAPFFR

C4orf33

26

Q8N1A6
AGAEDRMAGAPMAAA

AGAP9

176

Q5VTM2
NDAPDDMVLGMCFSG

B3GLCT

416

Q6Y288
PADLRGVAHNNLMAM

C4B

1206

P0C0L5
VAFDFAAREMAPNMA

ACAD8

51

Q9UKU7
IFDLAFMPAMNAVLG

BPIFB4

571

P59827
LGGLQRDEAPTAMFM

ALKBH1

256

Q13686
RDEAPTAMFMHSGDI

ALKBH1

261

Q13686
PGTLMAADRAKQMFG

GPS2

141

Q13227
SMDIQMFGPDALAAV

ARID2

451

Q68CP9
AADPVLSGLAQMMRE

ACVRL1

456

P37023
AMSGSGNLMDFLDEP

CLCN4

6

P51793
AGNRGFIDIMDMPNT

CDH23

3106

Q9H251
AMEMQPLKSAEGGDA

ATP2B2

356

Q01814
QEGMQAVMASDFAVP

ATP10A

1051

O60312
TPSRLAVAFQAMGAM

ACOXL

236

Q9NUZ1
ARDRMAGAPMAAAVQ

AGAP6

36

Q5VW22
MVLAAAMSQDADPSG

RBM20

1

Q5T481
NPEHASVAMRAMNGE

RBM3

56

P98179
HAAPMAAERAVAFMD

NR2F6

266

P10588
TGIPAMVDFAAMREA

IREB2

91

P48200
PQMSGMAALAAAAAA

HCFC1

541

P51610
AFVDMVARPSMGLVA

SLC16A1

306

P53985
MAAAAAAGAGPEMVR

MAPK1

1

P28482
RQMAELMPVGDNNFS

REST

71

Q13127
GDLFTAAMNMILPDF

IL17RA

476

Q96F46
PFGQASASIMAAFMD

NTRK1

366

P04629
FPDDMDNDIGILMTG

MED13L

2031

Q71F56
MPETTALGAAMAAGA

GK3P

451

Q14409
DPSSRNFIMEGGAMV

MCM5

421

P33992
GDFMSGRLMSLQENP

HHIPL1

496

Q96JK4
MAAAAAVEAAAPMGA

MMS19

1

Q96T76
AGFPALINRMKADGM

MGAM

1296

O43451
PRLMGEGFVVMQSND

KIAA1109

276

Q2LD37
IGVMDQSLMKDFPGA

EPB41L2

556

O43491
AAMPAFAGAMSLAGA

PCYOX1L

221

Q8NBM8
AFPMVELGASMEQAR

PLXNB3

316

Q9ULL4
FSQGDLEKAMGNRPM

PDE2A

831

O00408
RNFRLNSSDMDGEPM

NIPBL

1471

Q6KC79
FSMDDPDAGAMGAAA

EHBP1L1

1296

Q8N3D4
KDGVEVPFMREMAGA

PI4KA

1241

P42356
EVMLGSEPAMGESAA

NES

1081

P48681
MAAMAPALTDAAAEA

KANSL1

1

Q7Z3B3
PGEDMRQLADGSMDV

METTL7B

126

Q6UX53
MMAAKRADGAAPAGE

SLC7A5P2

26

Q9GIP4
EMEMFNVPELIGAQA

MEFV

581

O15553
AACMALVDAGVPMRA

EXOSC5

136

Q9NQT4
GFMAMFSAAEPNERG

PCOLCE2

136

Q9UKZ9
ARTVVGFGMDPDLQM

NELL1

16

Q92832
LMDSQDALAQAPMDG

FAM131B

171

Q86XD5
GPEVRMANADARNMG

PLOD1

351

Q02809
VREGGAAMAAGESMA

REXO2

26

Q9Y3B8
AGEDAMDVFRAMHPE

FADS2B

101

A8MWK0
MNAQETATGMAFEEP

HTATSF1

411

O43719
DAPEGGLDAMMQVAA

ITGB2

231

P05107
MELESVGMGGAAAFR

ARHGAP33

476

O14559
APADGFSDLAMQVMT

GLG1

1126

Q92896
AASPAVGTVGMDMDE

APOB

4001

P04114
ANEVMEDPGQGSSMA

CEFIP

931

Q711Q0
EDPGQGSSMARMEAS

CEFIP

936

Q711Q0
MQGMDPSALEALINF

KLHL18

81

O94889
AFNPGMEDILDSAMG

CSF1

286

P09603
MPETTALGAAMAAGA

GK2

451

Q14410
MSPEAFLGEANVMKA

BLK

276

P51451
QAQMEERAADRGMPF

POLQ

2296

O75417
GVGNADFSDMQMLDG

CPNE4

471

Q96A23
PFADLSNMEIGMKVA

ILK

391

Q13418
MAEGSQSAPEAGNDM

AGBL4

1

Q5VU57
AEDRMAGAPMAAAVQ

AGAP7P

36

Q5VUJ5
GPSMLDAVLGVMDAA

CDC42EP5

96

Q6NZY7
MDGNLPSGEAMVRQF

MAN2C1

336

Q9NTJ4
MFALGADAAPEGMAQ

MAN1A1

481

P33908
NGTVDFPEFLGMMAR

CALML3

61

P27482
GAAPRDMMDAFILSA

CYP1B1

286

Q16678
AQGEMFSVADMGRLA

C19orf54

166

Q5BKX5
GVMVARGLLANPAMF

DUS4L

236

O95620
LDMELEMAFFVGPGN

FAH

196

P16930
LQMAVMGTAAAFAPA

SLC22A12

181

Q96S37
SPARSAAAGAMAGVM

SLC25A35

101

Q3KQZ1
EAPRSMQGAIMGIFF

SLC15A3

486

Q8IY34
AGDASGVEAPMMIRL

SCARA5

381

Q6ZMJ2
AAGDNLEMMAPSRGS

CEP131

436

Q9UPN4
ELPQMMAAAADGLGS

ENOX1

16

Q8TC92
SLAFDMENDPVMGTH

NOA1

461

Q8NC60
NAAMAIDPVMDGASE

RNF2

211

Q99496
LAPERIADGTMAFMF

HGD

386

Q93099
AAMALFGDLVAAMAD

MROH5

1141

Q6ZUA9
FGMQDGSVNMREKPF

RPIA

296

P49247
LVAAGAAQPAASMVM

HSFX1

371

Q9UBD0
IGNMAAFDMNDPEAV

RTCB

96

Q9Y3I0
MPQVFQAEEARLGGM

RSPH6A

71

Q9H0K4
PNALMMEEEGAIIAG

RUFY3

196

Q7L099
AMLFTDAGAPMRGKV

SLC4A11

161

Q8NBS3
MATPSAAFEALMNGV

TCAF1

1

Q9Y4C2
EDEAMVLFLNMVAPG

POMGNT1

156

Q8WZA1
CFALSQPRAMMEEGE

NCOA3

226

Q9Y6Q9
MARFPKADLAAAGVM

PLXDC2

1

Q6UX71
RSGVEAFILGDVPMM

SNX33

191

Q8WV41
MVIMSEFSADPAGQG

SIK1B

1

A0A0B4J2F2
MVIMSEFSADPAGQG

SIK1

1

P57059
PNTFMAVAMDLCDRD

SIAE

356

Q9HAT2
AAMAAPSSDEAMNLI

PRDM1

536

O75626
GLFAMEPIAADEMVI

SETD1A

1581

O15047
PDIRGMENGNMDLAS

OSBPL2

406

Q9H1P3
AAGDEAMVQMLIDAG

ABTB2

531

Q8N961
QNGMMEPDDFRACLI

ACTN3

776

Q08043
FARIMTMVDPNAAGV

ACTN3

801

Q08043
FFLPGGARSEMMDDL

GFER

16

P55789
AGDRMAGAPMAAAVQ

AGAP5

36

A6NIR3
MERDDSGMVAPSNIF

ANKHD1

2441

Q8IWZ3
GQFMAGELMPREAIS

CLCN1

411

P35523
MAAAAAEEGMEPRAL

CLCN2

1

P51788
GMALPQGRLTFMDVA

ZNF610

16

Q8N9Z0
MELFSPDQDMREAGA

SCGB1A1

46

P11684
LMAGSQAPVTFEDMA

ZNF436

6

Q9C0F3
MFAATADPAALAAAM

VPS35L

81

Q7Z3J2
MNGEADAMSLDGGFV

TF

401

P02787
PFLRTDSGMHAMEDQ

SSH2

1291

Q76I76
FAAPAASIMVAEGML

PLPPR3

81

Q6T4P5
NMAAAGIPAMSAKDA

SAGE2P

241

A6NJ88
GFEPFAVNMNRDVAM

RYR3

1221

Q15413
IGENMNPDGMVALLD

TPT1

136

P13693
ATAAVQGAVAMAAPM

UBE2O

781

Q9C0C9
QGAVAMAAPMAGLME

UBE2O

786

Q9C0C9
GLSMTVEADPANMFN

TEX101

31

Q9BY14
FFMAVDGVAPRAKMN

XRN1

81

Q8IZH2
MSSDAEMAIFGEAAP

MYH13

1

Q9UKX3
AAMNGQLPFAVVGSM

SEPTIN10

251

Q9P0V9
EDDQSGVADMAMFPG

ZNF697

91

Q5TEC3
GVADMAMFPGLSESD

ZNF697

96

Q5TEC3
DEMDVAPLNLGMIAA

SNRNP200

1806

O75643
DNMGRAGEMELKPFN

TOP2A

196

P11388
MAEMNPAQGHVVFED

ZNF547

1

Q8IVP9
AMIAAGLVDDPRAMV

TRAP1

676

Q12931
QMMPEVRGALFGANA

ATP6V1E1

206

P36543
DSGHIRGAVNMPFMD

TST

201

Q16762
RGAVNMPFMDFLTED

TST

206

Q16762
PLFGDQMDNAKRMET

UGT1A6

391

P19224
QPSAAMAATDSMRGE

TMUB1

51

Q9BVT8
MAATDSMRGEAPGAE

TMUB1

56

Q9BVT8
GKFGMLAPNRDDENM

TRANK1

2341

O15050
MNGEADCPTDLEMAA

UBTF

1

P17480
ASAAAVDAGMAMAGQ

PTBP1

166

P26599
VDAGMAMAGQSPVLR

PTBP1

171

P26599
FGPARDDVLAMAVKM

ZMYM3

971

Q14202
PQLVDMAAQIADGMA

YES1

371

P07947
GAREAFLEQMMSLEG

LAMC3

1071

Q9Y6N6
SNLPGLMDMQAVDRA

LRP4

1291

O75096
LMDMQAVDRAQPLGF

LRP4

1296

O75096
MPGAAAAAAAAAAAM

LHFPL3

1

Q86UP9
EFLNVPDQGMAGMQR

MYO1F

1006

O00160
VAAMNMAGLGAPSAV

MYOM1

1011

P52179
GRGLNAMANETPDFM

NEB

6021

P20929