Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	synapse assembly	SEMA4D DSCAM ASIC2 ACHE USP9X DVL1 SIX1 ZDHHC8 ADGRF1	1.49e-05	308	97	9	GO:0007416
GeneOntologyBiologicalProcess	kidney mesenchyme development	SIX1 SIX2 SMAD4	5.40e-05	16	97	3	GO:0072074
GeneOntologyBiologicalProcess	ear development	SPRY2 DVL1 SIX1 TECTA DCHS1 OTOP1 SIX2 OTOG	6.01e-05	285	97	8	GO:0043583
GeneOntologyBiologicalProcess	developmental growth involved in morphogenesis	SEMA4D SPRY2 DSCAM USP9X DVL1 SPART SIX1 MEGF8	8.40e-05	299	97	8	GO:0060560
GeneOntologyBiologicalProcess	ear morphogenesis	SPRY2 DVL1 SIX1 TECTA OTOP1 SIX2	8.87e-05	154	97	6	GO:0042471
Domain	Kringle	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	IPR000001
Domain	Kringle_CS	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	IPR018056
Domain	KRINGLE_2	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	PS50070
Domain	Kringle	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	PF00051
Domain	KRINGLE_1	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	PS00021
Domain	KR	HGF HGFAC PIK3IP1 PLG	1.48e-06	17	96	4	SM00130
Domain	Kringle-like	HGF HGFAC PIK3IP1 PLG	2.11e-05	32	96	4	IPR013806
Domain	DVL-1	DVL1P1 DVL1	2.61e-05	2	96	2	IPR008340
Domain	Dishevelled_fam	DVL1P1 DVL1	1.56e-04	4	96	2	IPR008339
Domain	Dishevelled	DVL1P1 DVL1	1.56e-04	4	96	2	PF02377
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	1.56e-04	4	96	2	IPR003351
Domain	PAN_AP	HGF PLG	2.59e-04	5	96	2	SM00473
Domain	PAN	HGF PLG	5.40e-04	7	96	2	PS50948
Domain	RNase_Zc3h12a	NYNRIN ZC3H12C	5.40e-04	7	96	2	PF11977
Domain	Pan_app	HGF PLG	5.40e-04	7	96	2	IPR003609
Domain	DIX	DVL1P1 DVL1	5.40e-04	7	96	2	PF00778
Domain	RNase_Zc3h12_NYN	NYNRIN ZC3H12C	5.40e-04	7	96	2	IPR021869
Domain	SIX1_SD	SIX1 SIX2	5.40e-04	7	96	2	PF16878
Domain	PAN_1	HGF PLG	5.40e-04	7	96	2	PF00024
Domain	SIX1_SD	SIX1 SIX2	5.40e-04	7	96	2	IPR031701
Domain	DIX	DVL1P1 DVL1	5.40e-04	7	96	2	IPR001158
Domain	DIX	DVL1P1 DVL1	5.40e-04	7	96	2	PS50841
Domain	DAX	DVL1P1 DVL1	5.40e-04	7	96	2	SM00021
Domain	PSI	SEMA4D MST1R MEGF8	5.86e-04	32	96	3	PF01437
Domain	Plexin_repeat	SEMA4D MST1R MEGF8	5.86e-04	32	96	3	IPR002165
Domain	E3_UB_ligase_RBR	RNF144A RNF19B	1.15e-03	10	96	2	IPR031127
Domain	IGc2	GP6 SEMA4D ADAMTSL1 DSCAM MYOM3 OBSCN	1.34e-03	235	96	6	SM00408
Domain	Ig_sub2	GP6 SEMA4D ADAMTSL1 DSCAM MYOM3 OBSCN	1.34e-03	235	96	6	IPR003598
Domain	fn3	DSCAM MYOM3 OBSCN LRRN4CL PTPRH	1.49e-03	162	96	5	PF00041
Domain	PSI	SEMA4D MST1R MEGF8	1.50e-03	44	96	3	IPR016201
Domain	-	SEMA4D STXBP5 WDR81 GEMIN5 MST1R ERCC8 DMWD	1.65e-03	333	96	7	2.130.10.10
Domain	TIL	TECTA OTOG	1.67e-03	12	96	2	PF01826
Domain	C8	TECTA OTOG	1.67e-03	12	96	2	PF08742
Domain	PSI	SEMA4D MST1R MEGF8	1.70e-03	46	96	3	SM00423
Domain	WD40/YVTN_repeat-like_dom	SEMA4D STXBP5 WDR81 GEMIN5 MST1R ERCC8 DMWD	1.71e-03	335	96	7	IPR015943
Domain	Unchr_dom_Cys-rich	TECTA OTOG	1.97e-03	13	96	2	IPR014853
Domain	C8	TECTA OTOG	1.97e-03	13	96	2	SM00832
Domain	CUB	CSMD3 ADGRG6 MEGF8	2.04e-03	49	96	3	PF00431
Domain	CUB	CSMD3 ADGRG6 MEGF8	2.17e-03	50	96	3	SM00042
Domain	IBR	RNF144A RNF19B	2.29e-03	14	96	2	SM00647
Domain	TIL_dom	TECTA OTOG	2.29e-03	14	96	2	IPR002919
Domain	IBR	RNF144A RNF19B	2.29e-03	14	96	2	PF01485
Domain	-	CSMD3 ADGRG6 MEGF8	2.42e-03	52	96	3	2.60.120.290
Domain	CUB	CSMD3 ADGRG6 MEGF8	2.56e-03	53	96	3	PS01180
Domain	IBR_dom	RNF144A RNF19B	2.63e-03	15	96	2	IPR002867
Domain	FN3	DSCAM MYOM3 OBSCN LRRN4CL PTPRH	2.67e-03	185	96	5	SM00060
Domain	ig	GP6 SEMA4D DSCAM MYOM3 OBSCN	2.99e-03	190	96	5	PF00047
Domain	Immunoglobulin	GP6 SEMA4D DSCAM MYOM3 OBSCN	2.99e-03	190	96	5	IPR013151
Domain	VWD	TECTA OTOG	2.99e-03	16	96	2	SM00216
Domain	VWF_type-D	TECTA OTOG	2.99e-03	16	96	2	IPR001846
Domain	VWFD	TECTA OTOG	2.99e-03	16	96	2	PS51233
Domain	VWD	TECTA OTOG	2.99e-03	16	96	2	PF00094
Domain	CUB_dom	CSMD3 ADGRG6 MEGF8	3.15e-03	57	96	3	IPR000859
Domain	FN3	DSCAM MYOM3 OBSCN LRRN4CL PTPRH	3.65e-03	199	96	5	PS50853
Domain	VWC_out	TECTA OTOG	4.22e-03	19	96	2	SM00215
Domain	FN3_dom	DSCAM MYOM3 OBSCN LRRN4CL PTPRH	4.49e-03	209	96	5	IPR003961
Domain	C2	INPP4A PLA2G4F CCDC33 CPNE7	5.47e-03	137	96	4	SM00239
Domain	DEP	DVL1P1 DVL1	5.65e-03	22	96	2	PF00610
Domain	DEP	DVL1P1 DVL1	5.65e-03	22	96	2	PS50186
Domain	DEP	DVL1P1 DVL1	5.65e-03	22	96	2	SM00049
Domain	DEP_dom	DVL1P1 DVL1	6.17e-03	23	96	2	IPR000591
Domain	C2	INPP4A PLA2G4F CCDC33 CPNE7	6.20e-03	142	96	4	PS50004
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPRY2 DVL1 MYOM3 OBSCN GEMIN5 ZDHHC8 RNF43 MST1R MEGF8 FAM83F CPSF1 DMWD PRRT4 ABTB2 CREB3	5.50e-07	1105	99	15	35748872
Pubmed	Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes.	HGF MST1R	8.02e-06	2	99	2	22287599
Pubmed	Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.	SIX1 SIX2	8.02e-06	2	99	2	33281191
Pubmed	Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.	HGF HGFAC	8.02e-06	2	99	2	8631970
Pubmed	Structure and function of hepatocyte growth factor.	HGF HGFAC	8.02e-06	2	99	2	1838014
Pubmed	Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator.	HGF HGFAC	8.02e-06	2	99	2	15172968
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	8.02e-06	2	99	2	8644734
Pubmed	Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).	HGF HGFAC	8.02e-06	2	99	2	25998175
Pubmed	Elevated serum concentrations of activated hepatocyte growth factor activator in patients with multiple myeloma.	HGF HGFAC	8.02e-06	2	99	2	18691255
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	TECTA OTOP1 OTOG	1.48e-05	17	99	3	20856818
Pubmed	Cross-talk between the proto-oncogenes Met and Ron.	HGF MST1R	2.40e-05	3	99	2	10871856
Pubmed	Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer.	HGF HGFAC	2.40e-05	3	99	2	18422749
Pubmed	HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion.	HGF SMAD4	2.40e-05	3	99	2	20852387
Pubmed	Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome.	SIX1 SIX2	2.40e-05	3	99	2	11734542
Pubmed	Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.	MST1R SMAD4	2.40e-05	3	99	2	18310076
Pubmed	Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.	SIX1 SIX2	2.40e-05	3	99	2	15735644
Pubmed	Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro.	HGF HGFAC	2.40e-05	3	99	2	11032833
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL1P1 DVL1	4.79e-05	4	99	2	8817329
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL1P1 DVL1	4.79e-05	4	99	2	9192851
Pubmed	Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators.	SIX1 SIX2	4.79e-05	4	99	2	26884396
Pubmed	Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.	DVL1P1 DVL1	4.79e-05	4	99	2	20639201
Pubmed	Role of hypoxia on microRNA-dependant regulation of HGFA - HGF - c-Met signalling pathway in human progenitor and mature endothelial cells.	HGF HGFAC	4.79e-05	4	99	2	36182093
Pubmed	Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.	SIX1 SIX2	4.79e-05	4	99	2	25670082
Pubmed	Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.	DVL1 RNF43	4.79e-05	4	99	2	25891077
Pubmed	Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.	HGF TECTA	4.79e-05	4	99	2	33976695
Pubmed	Six family genes control the proliferation and differentiation of muscle satellite cells.	SIX1 SIX2	4.79e-05	4	99	2	20696153
Pubmed	Comparative characterization of the HGF/Met and MSP/Ron systems in primary pancreatic adenocarcinoma.	HGF MST1R	4.79e-05	4	99	2	31254927
Pubmed	A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB.	SIX1 SIX2	4.79e-05	4	99	2	30894749
Pubmed	A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane.	TECTA OTOG	4.79e-05	4	99	2	28935705
Pubmed	Retinoic acid deficiency impairs the vestibular function.	TECTA OTOP1 OTOG	5.55e-05	26	99	3	23536097
Pubmed	Tissue and developmental distribution of Six family gene products.	SIX1 SIX2	7.98e-05	5	99	2	9551859
Pubmed	Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x-SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis.	USP9X SMAD4	7.98e-05	5	99	2	28115363
Pubmed	Identification and expression of six family genes in mouse retina.	SIX1 SIX2	7.98e-05	5	99	2	8814301
Pubmed	Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders.	SIX1 SIX2	7.98e-05	5	99	2	26034287
Pubmed	Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.	SLC22A1 PLG	7.98e-05	5	99	2	9933568
Pubmed	Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.	SIX1 SIX2	7.98e-05	5	99	2	25670083
Pubmed	Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation.	SIX1 SIX2	7.98e-05	5	99	2	35178390
Pubmed	The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters.	SLC22A1 PLG	7.98e-05	5	99	2	8854860
Pubmed	The NYN domains: novel predicted RNAses with a PIN domain-like fold.	NYNRIN ZC3H12C	7.98e-05	5	99	2	17114934
Pubmed	Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site.	SIX1 SIX2	1.19e-04	6	99	2	9826681
Pubmed	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.	USP9X SMAD4	1.19e-04	6	99	2	19135894
Pubmed	Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.	SIX1 SIX2	1.19e-04	6	99	2	20074369
Pubmed	The expression profile and clinic significance of the SIX family in non-small cell lung cancer.	SIX1 SIX2	1.19e-04	6	99	2	27821176
Pubmed	DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.	HGF DSCAM	1.19e-04	6	99	2	18585357
Pubmed	Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development.	SIX1 SIX2	1.19e-04	6	99	2	19900183
Pubmed	Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base.	SIX1 SIX2	1.67e-04	7	99	2	20515681
Pubmed	USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.	DVL1 RNF43	1.67e-04	7	99	2	33786993
Pubmed	SIX1 cooperates with RUNX1 and SMAD4 in cell fate commitment of Müllerian duct epithelium.	SIX1 SMAD4	1.67e-04	7	99	2	32572167
Pubmed	Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein.	SIX1 SIX2	1.67e-04	7	99	2	12215533
Pubmed	Six3 and Six6 activity is modulated by members of the groucho family.	SIX1 SIX2	2.22e-04	8	99	2	12441302
Pubmed	Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.	SLC22A1 PLG	2.22e-04	8	99	2	11562346
Pubmed	Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia.	SIX1 SIX2	2.22e-04	8	99	2	10471511
Pubmed	Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins.	SIX1 SIX2	2.22e-04	8	99	2	11950062
Pubmed	Identification of three novel Smad binding proteins involved in cell polarity.	DVL1 SMAD4	2.22e-04	8	99	2	12650946
Pubmed	Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.	SLC22A1 PLG	2.22e-04	8	99	2	16204191
Pubmed	A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).	DVL1P1 DVL1	2.22e-04	8	99	2	19643732
Pubmed	Lmx1b expression during joint and tendon formation: localization and evaluation of potential downstream targets.	SIX1 SIX2	2.22e-04	8	99	2	15183306
Pubmed	Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme.	SIX1 SIX2	2.22e-04	8	99	2	15634706
Pubmed	Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.	SIX1 SIX2	2.22e-04	8	99	2	11313460
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	DVL1 RNF43	2.85e-04	9	99	2	32965059
Pubmed	Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation.	SLC22A1 PLG	2.85e-04	9	99	2	25918552
Pubmed	Pleiotropic effects in Eya3 knockout mice.	SIX1 SIX2	2.85e-04	9	99	2	19102749
Pubmed	Six1 is required for the early organogenesis of mammalian kidney.	SIX1 SIX2	2.85e-04	9	99	2	12783782
Pubmed	Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.	USP9X GEMIN5	2.85e-04	9	99	2	23112048
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	POLR1A DSCAM SMCHD1 GEMIN5 CPSF1	2.89e-04	202	99	5	24639526
Pubmed	Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme.	SIX1 SIX2	3.56e-04	10	99	2	16442091
Pubmed	Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis.	SIX1 SIX2	3.56e-04	10	99	2	16938278
Pubmed	Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene.	SLC22A1 PLG	4.34e-04	11	99	2	9268631
Pubmed	Embryonic origin and remodeling of the urinary and digestive outlets.	SIX1 SIX2	4.34e-04	11	99	2	23390542
Pubmed	Homeobox genes and connective tissue patterning.	SIX1 SIX2	4.34e-04	11	99	2	7720577
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	TECTA OTOG	4.34e-04	11	99	2	31776257
Pubmed	A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.	POLR1A ERCC8	6.13e-04	13	99	2	20541997
Pubmed	Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development.	SIX1 SIX2	6.13e-04	13	99	2	30905259
Pubmed	Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb.	SLC22A1 PLG	7.14e-04	14	99	2	11641723
Pubmed	New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.	SLC8A2 DMWD	7.14e-04	14	99	2	11526197
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	SPRY2 SIX2	7.14e-04	14	99	2	31242448
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	USP9X UHRF1	7.14e-04	14	99	2	27626314
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	USP9X DVL1 SPART	7.49e-04	62	99	3	31340145
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	SPRY2 SIX2	8.22e-04	15	99	2	7543410
Pubmed	Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.	USP9X SMCHD1	8.22e-04	15	99	2	30970248
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	POLR1A USP9X SMCHD1 SPART GEMIN5 XRN1 CPSF1	8.53e-04	534	99	7	35032548
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	TTYH1 TPCN2 HAGHL RNF144A SPART SLC8A2 DMWD DGAT1	8.64e-04	697	99	8	28298427
Pubmed	Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.	MELTF SMAD4	1.06e-03	17	99	2	38865240
Pubmed	Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.	SIX1 SIX2	1.06e-03	17	99	2	30367465
Pubmed	Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression.	SIX1 SIX2	1.06e-03	17	99	2	29771971
Pubmed	Genetic Hearing Loss Overview	HGF SIX1 TECTA	1.07e-03	70	99	3	20301607
Pubmed	Searching QTL by gene expression: analysis of diabesity.	DVL1 TFF1 PLG	1.11e-03	71	99	3	15760467
Pubmed	Genome-wide association of mood-incongruent psychotic bipolar disorder.	INPP4A MYOM3	1.19e-03	18	99	2	23092984
Pubmed	Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.	SIX1 SIX2	1.19e-03	18	99	2	14628042
Pubmed	An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.	SMCHD1 UHRF1	1.19e-03	18	99	2	24025402
Pubmed	Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors.	SIX1 SIX2	1.19e-03	18	99	2	32243674
Pubmed	Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.	ASIC2 STXBP5	1.19e-03	18	99	2	21810271
Pubmed	The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice.	SIX1 SIX2	1.33e-03	19	99	2	32554463
Pubmed	Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.	SEMA4D SPRY2	1.47e-03	20	99	2	22863734
Pubmed	The murine Fgfrl1 receptor is essential for the development of the metanephric kidney.	SIX1 SIX2	1.47e-03	20	99	2	19715689
Pubmed	Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching.	DCHS1 SIX2	1.47e-03	20	99	2	26116666
Pubmed	Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.	DSCAM TFF1	1.47e-03	20	99	2	16009131
Pubmed	Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.	POLR1A TFF1	1.79e-03	22	99	2	9582279
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ADAMTSL1 TPCN2 USP9X	1.80e-03	84	99	3	15203218
Pubmed	Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme.	HGF SPRY2	1.95e-03	23	99	2	20934536
Cytoband	14q23.1	TMEM30B ARID4A SIX1	1.47e-04	47	99	3	14q23.1
GeneFamily	SINE class homeoboxes	SIX1 SIX2	1.83e-04	6	64	2	525
GeneFamily	Fibronectin type III domain containing	DSCAM MYOM3 OBSCN LRRN4CL PTPRH	2.55e-04	160	64	5	555
GeneFamily	Cadherin related	CDHR5 DCHS1	1.62e-03	17	64	2	24
GeneFamily	WD repeat domain containing	STXBP5 WDR81 GEMIN5 ERCC8 DMWD	2.34e-03	262	64	5	362
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ADAMTSL1 DSCAM MYOM3 OBSCN	2.54e-03	161	64	4	593
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	TMEM30B SYNDIG1L DSCAM ASIC2 ACHE SLC6A17 FAM43B SLC8A2 FAM83F GRIN3B SIX2	7.61e-07	438	98	11	M1954
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	TMEM30B SYNDIG1L DSCAM ASIC2 ACHE SLC6A17 FAM43B SLC8A2 FAM83F GRIN3B SIX2	7.96e-07	440	98	11	MM832
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN	SEMA4D SMCHD1 RNF144A RNF43 SAMD9L NCOA7 ABTB2	9.77e-06	198	98	7	M4264
Coexpression	GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP	TMEM30B HGF RNF19B SIX1 TECTA MST1R PLG	1.04e-05	200	98	7	M8222
Coexpression	SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6	USP9X PER3 UHRF1 PLA2G4F	5.03e-05	54	98	4	MM537
Coexpression	SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6	USP9X PER3 UHRF1 PLA2G4F	5.41e-05	55	98	4	M1284
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	TTYH1 SYNDIG1L DSCAM ACHE FAM43B SLC8A2 KNDC1 OTOP1 GRIN3B CPNE7	7.44e-05	591	98	10	M2019
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	TTYH1 SYNDIG1L DSCAM ACHE FAM43B SLC8A2 KNDC1 OTOP1 GRIN3B CPNE7	8.55e-05	601	98	10	MM866
Coexpression	GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN	NLRP12 TPCN2 INPP4A DVL1 PER3 UHRF1	9.10e-05	194	98	6	M7568
Coexpression	GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN	TTYH1 SEMA4D RNF19B TFF1 ZC3H12C ABTB2	1.05e-04	199	98	6	M9851
Coexpression	GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN	ARID4A HAGHL PCDHB12 PACRGL DMWD SMAD4	1.08e-04	200	98	6	M7868
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF HGFAC DSCAM ASIC2 ACHE CSMD3 PER3 CPNE7	7.05e-09	180	99	8	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASIC2 SLC6A17 CSMD3 GDF10 MST1R DMTN CPNE7	3.25e-07	200	99	7	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASIC2 SLC6A17 CSMD3 GDF10 MST1R DMTN CPNE7	3.25e-07	200	99	7	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASIC2 SLC6A17 CSMD3 GDF10 MST1R DMTN CPNE7	3.25e-07	200	99	7	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ASIC2 FAM43B KNDC1 OTOP1 PLG CCDC33	8.49e-07	144	99	6	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	facs-Lung-Endomucin-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 TTC7A ABTB2 DGAT1 MCEMP1 RUFY4	1.94e-06	166	99	6	5126d8f02314717eed341d867856fd4fe16c5118
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 TTC7A ABTB2 DGAT1 MCEMP1 RUFY4	1.94e-06	166	99	6	3037bdca38c3a65eacfa644219cc43c54e303749
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF HGFAC SPRY2 SIX1 RNF43 RUFY4	2.55e-06	174	99	6	e9e4532a474b4b0938a50ff85c9508aca53cd3ae
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF DSCAM ASIC2 ACHE CSMD3 CPNE7	3.01e-06	179	99	6	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 DSCAM INPP4A CSMD3 NCOA7 ADGRF1	3.21e-06	181	99	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TMEM30B TMEM61 SIX1 TFF1 PLA2G4F SIX2	3.31e-06	182	99	6	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF HGFAC DSCAM ASIC2 ACHE PER3	3.75e-06	186	99	6	2f103ce2427f9cf2c1fafb6bd6045c5863a47549
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF HGFAC DSCAM ASIC2 ACHE PER3	4.11e-06	189	99	6	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 HAGHL PCDHB12 GDF10 DENND4B	1.43e-05	138	99	5	6b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 INPP4A CSMD3 NCOA7 CPNE7	1.88e-05	146	99	5	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 TPCN2 RNF144A ABTB2 MCEMP1	2.01e-05	148	99	5	b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 TPCN2 RNF144A ABTB2 MCEMP1	2.01e-05	148	99	5	ba277c898678dd36f8dc1d681301c71901b89055
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HGFAC NLRP12 TMEM61 ADGRG6	2.25e-05	74	99	4	0288a3f4eafbc359d01cde4ba58f946dd07c77cb
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HGFAC NLRP12 TMEM61 ADGRG6	2.25e-05	74	99	4	57884ade66fe39398351685189df5efd7aea0aab
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HGFAC NLRP12 TMEM61 ADGRG6	2.25e-05	74	99	4	13093139a75bfe11f6b032c9fb402efcc703551c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HGFAC NLRP12 TMEM61 ADGRG6	2.25e-05	74	99	4	7f7de9e8142d2435391ee965cee5628e412f0705
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 DSCAM SIX1 ADGRF1 CPNE7	2.43e-05	154	99	5	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|GI_small-bowel / Manually curated celltypes from each tissue	TMEM30B SPRY2 HAGHL MST1R FAM83F	2.51e-05	155	99	5	1c67f58ed79331addbc012dab0cb09a7f350aedb
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B CDHR5 SIX1 NYNRIN KNDC1	3.10e-05	162	99	5	3dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCell	facs-Thymus-Epithelium-3m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B CDHR5 SIX1 NYNRIN KNDC1	3.10e-05	162	99	5	0a7138266054ea5954649c8b61ef93905d56b068
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B CDHR5 SIX1 NYNRIN KNDC1	3.10e-05	162	99	5	25323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTYH1 SYNDIG1L LRRN4CL WFDC12 CPNE7	3.38e-05	165	99	5	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTYH1 SYNDIG1L LRRN4CL WFDC12 CPNE7	3.38e-05	165	99	5	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTYH1 SYNDIG1L LRRN4CL WFDC12 CPNE7	3.38e-05	165	99	5	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTYH1 SYNDIG1L LRRN4CL WFDC12 CPNE7	3.38e-05	165	99	5	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GP6 RNF144A MYOM3 MCEMP1 RUFY4	3.38e-05	165	99	5	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SEMA4D NLRP12 MEGF8 ABTB2 MCEMP1	3.58e-05	167	99	5	820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM RNF43 P2RX5 UHRF1 PLA2G4F	3.68e-05	168	99	5	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	droplet-Lung-nan-18m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GP6 HGF RNF43 WFDC12 DGAT1	3.79e-05	169	99	5	f2e20049a17eee533d49bd5f24a51962d123d132
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SPRY2 ADAMTSL1 PLG DGAT1	3.79e-05	169	99	5	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SPRY2 P3H3 GDF10 LRRN4CL	3.79e-05	169	99	5	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SPRY2 ADAMTSL1 PLG DGAT1	3.79e-05	169	99	5	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	droplet-Lung-nan-18m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GP6 HGF RNF43 WFDC12 DGAT1	3.79e-05	169	99	5	4c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGFAC CSMD3 PIK3IP1 LRRN4CL GRIN3B	4.12e-05	172	99	5	a03f30a996a9474ad4cccd209476423a042df002
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGFAC CSMD3 PIK3IP1 LRRN4CL GRIN3B	4.12e-05	172	99	5	f92a53ad2e464cd68ba1714bcc1d5911479cdf1c
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 ADAMTSL1 GARIN5A WDR81 PRRT4	4.24e-05	173	99	5	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF SPRY2 ARID4A RNF43 DGAT1	4.24e-05	173	99	5	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF SPRY2 ARID4A RNF43 DGAT1	4.24e-05	173	99	5	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TTYH1 SIX1 TFF1 FAM83F NCOA7	4.35e-05	174	99	5	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ADAMTSL1 RNF43 DMWD RUFY4	4.47e-05	175	99	5	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ADAMTSL1 RNF43 DMWD RUFY4	4.47e-05	175	99	5	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A4 CDHR5 SAMD9L PTPRH NCOA7	4.60e-05	176	99	5	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF HGFAC SPRY2 ADAMTSL1 PLG	4.72e-05	177	99	5	c1f838e425ebb04482829b1957e3c1347127e6de
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF HGFAC SPRY2 ADAMTSL1 PLG	4.85e-05	178	99	5	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SPRY2 ADAMTSL1 RNF43 PLG	4.85e-05	178	99	5	41745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SPRY2 ADAMTSL1 RNF43 PLG	4.85e-05	178	99	5	eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 DSCAM INPP4A NCOA7 ADGRF1	4.98e-05	179	99	5	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DSCAM ASIC2 ACHE PER3	5.12e-05	180	99	5	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	severe-CD8+_T_naive\|World / disease stage, cell group and cell class	HAGHL RNF144A ZDHHC8 RNF43 DMTN	5.25e-05	181	99	5	69eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	USP9X SMCHD1 SAMD9L XRN1 NCOA7	5.53e-05	183	99	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 DSCAM INPP4A NCOA7 ADGRF1	5.53e-05	183	99	5	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 OBSCN CSMD3 MELTF OTOG	5.68e-05	184	99	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 OBSCN CSMD3 MELTF OTOG	5.68e-05	184	99	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 OBSCN CSMD3 MELTF OTOG	5.68e-05	184	99	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TMEM61 SIX1 TFF1 PLA2G4F SIX2	5.98e-05	186	99	5	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 INPP4A CSMD3 NCOA7 ADGRF1	6.13e-05	187	99	5	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GP6 TECTA CSMD3 CPNE7	6.27e-05	96	99	4	78f19fee755061b4144b1beebb60f4e8bc4dbf0d
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TMEM61 SLC6A17 TFF1 PTPRH SIX2	6.77e-05	191	99	5	19832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ASIC2 ACHE BEAN1 FAM43B DMTN	6.77e-05	191	99	5	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ASIC2 ACHE BEAN1 FAM43B DMTN	6.77e-05	191	99	5	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 P3H3 GDF10 LRRN4CL SIX2	6.94e-05	192	99	5	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM30B SIX1 MST1R NYNRIN GRIN3B	6.94e-05	192	99	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DSCAM ASIC2 ACHE PER3	6.94e-05	192	99	5	550a6574a93acadb43c449094565c73ca51a0c5c
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 P3H3 GDF10 LRRN4CL SIX2	6.94e-05	192	99	5	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM30B SIX1 MST1R NYNRIN GRIN3B	6.94e-05	192	99	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TMEM61 SLC6A17 TFF1 PTPRH SIX2	6.94e-05	192	99	5	4d3a1c267739b1479217144656986972fc86db43
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 P3H3 GDF10 LRRN4CL SIX2	6.94e-05	192	99	5	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DSCAM ASIC2 ACHE PER3	7.11e-05	193	99	5	6995ee29bf403a71247de92a37dfd851be5acf2e
ToppCell	moderate-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNF19B SAMD9L XRN1 NCOA7 ABTB2	7.11e-05	193	99	5	22455801194bd8c73c5c397f5eac4f723429c383
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INPP4A PIK3IP1 TTC7A NCOA7 CPNE7	7.47e-05	195	99	5	69201b1172bcf0999c726516e4d30863afceab0b
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM61 DSCAM ASIC2 SLC6A17 SLC8A2	8.03e-05	198	99	5	2591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HAGHL OBSCN KNDC1 DMTN CPNE7	8.41e-05	200	99	5	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM30B SLC8A2 RUFY4 OTOG	9.92e-05	108	99	4	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 STXBP5 FAM83F MCEMP1	1.18e-04	113	99	4	ec4b89e727e1b921b9cb17443774955b95814dd4
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SYNDIG1L ADGRG6 SAMD9L PLA2G4F	1.85e-04	127	99	4	cd69ba386796715e87674f8324d2acaad1d4d094
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	HGFAC NYNRIN SLC22A1 PLG DMWD	8.31e-05	137	95	5	EFO_0004611, EFO_0008591
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	1.02e-04	5	95	2	DOID:11198 (is_implicated_in)
Disease	suberoylcarnitine (C8-DC) measurement	SLC17A4 SLC22A1	1.02e-04	5	95	2	EFO_0800382
Disease	arachidonate 15-lipoxygenase B measurement	NLRP12 GUCY2D	2.13e-04	7	95	2	EFO_0801391
Disease	Liver Diseases, Parasitic	RNF43 SMAD4	3.64e-04	9	95	2	C0023897
Disease	prostate carcinoma	HGF ADAMTSL1 TPCN2 POLR1A SIX1 RNF43 GGCX FAM83F SLC22A1 DENND4B	5.98e-04	891	95	10	EFO_0001663
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	HGFAC NYNRIN SLC22A1 DMWD	6.23e-04	120	95	4	EFO_0004611, EFO_0004639
Disease	Benign tumor of pancreas	RNF43 SMAD4	7.82e-04	13	95	2	C0347284
Disease	testosterone measurement	HGF HGFAC POLR1A DSCAM ACHE DLGAP4 WDR81 CSMD3 CEP68 PER3 NYNRIN KNDC1	8.03e-04	1275	95	12	EFO_0004908
Disease	Adenocarcinoma Of Esophagus	SPART SMAD4	9.10e-04	14	95	2	C0279628
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	HGFAC SLC22A1 PLG	1.02e-03	61	95	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	triglycerides in small HDL measurement	HGFAC SLC22A1 PLG	1.07e-03	62	95	3	EFO_0022158
Disease	phospholipids in large VLDL measurement	HGFAC SLC22A1 PLG	1.07e-03	62	95	3	EFO_0022169
Disease	myopia (is_implicated_in)	HGF CPSF1	1.20e-03	16	95	2	DOID:11830 (is_implicated_in)
Disease	Blood Coagulation Disorders	GGCX SMAD4	1.20e-03	16	95	2	C0005779
Disease	triglycerides in small LDL measurement	HGFAC SLC22A1 PLG	1.22e-03	65	95	3	EFO_0022323
Disease	copine-1 measurement	NLRP12 DLGAP4	1.35e-03	17	95	2	EFO_0008102
Disease	free cholesterol in large VLDL measurement	HGFAC SLC22A1 PLG	1.39e-03	68	95	3	EFO_0022265
Disease	Pancreatic carcinoma	RNF43 SMAD4	1.69e-03	19	95	2	C0235974
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	RNF43 SMAD4	1.69e-03	19	95	2	DOID:4928 (is_marker_for)
Disease	Nonsyndromic genetic hearing loss	HGF SIX1 TECTA	1.92e-03	76	95	3	cv:C5680182
Disease	nicotine dependence	ADAMTSL1 DVL1P1 DVL1	2.07e-03	78	95	3	EFO_0003768
Disease	Nonsyndromic Deafness	HGF TECTA OTOG	2.30e-03	81	95	3	C3711374
Disease	arginine measurement	ASIC2 FAM83F	2.48e-03	23	95	2	EFO_0020990
Disease	Intrahepatic Cholangiocarcinoma	RNF43 SMAD4	2.70e-03	24	95	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	RNF43 SMAD4	2.70e-03	24	95	2	C3805278
Disease	lipid measurement, lipoprotein measurement	HGFAC NYNRIN SLC22A1	3.10e-03	90	95	3	EFO_0004529, EFO_0004732
Disease	linoleic acid measurement	HGFAC WDR81 SLC22A1 PLG	3.11e-03	186	95	4	EFO_0006807
Disease	Cholangiocarcinoma	RNF43 SMAD4	3.17e-03	26	95	2	C0206698

Protein segments in the cluster

Peptide	Gene	Start	Entry
CSLPRAWALFPPSDD	TTYH1	411	Q9H313
DCLYLNVWTPYPRPT	ACHE	126	P22303
PPRPCEAYRAEWKLC	C22orf39	46	Q6P5X5
ERTEWYPALVISPSC	ARID4A	186	P29374
RAWDYPLPSCIAECG	CSMD3	1401	Q7Z407
PACKDGSEPWPYVVV	CCDC33	251	Q8N5R6
AEYWACVLPDSLPPS	CEP68	271	Q76N32
EDSYTWFPPSCLDPQ	ADGRF1	106	Q5T601
WPSIQPSEYVLPCPD	ADGRG6	536	Q86SQ4
DLRPPWFLPCTFSDG	CDHR5	231	Q9HBB8
KDPYSWPAPCLVIAA	DGAT1	126	O75907
CLWDLTEDVLYPHPP	DMWD	441	Q09019
LPSKCPSWEEDYTPV	DLGAP4	426	Q9Y2H0
EQRLTYLPPPWGECR	ASIC2	276	Q16515
SYFLWEDDCPDPPAL	HAGHL	116	Q6PII5
DPDTGECWREPPAYT	P3H3	591	Q8IVL6
PDSHAYWIRPEDPFC	INPP4A	576	Q96PE3
YWIRPEDPFCDVPSS	INPP4A	581	Q96PE3
LSDTSCEPPAPDTWY	DCHS1	3076	Q96JQ0
TETAWPPLPAVPCDY	LRRN4CL	36	Q8ND94
PWACDPIFSRARPDL	GUCY2D	61	Q02846
FLRSCPDLLPDWPLE	FAM43B	36	Q6ZT52
YSEPPRWPRALEVLC	GDF10	136	P55107
YEWLPVSNDPDNPCS	ADAMTSL1	106	Q8N6G6
SYDAPWPVRKIPLRC	CPSF1	1006	Q10570
RDPYLWSAPSDPLEL	GP6	186	Q9HCN6
PPETARDATLFCEPW	PER3	641	P56645
PSPELYSLHCPDRTW	MEGF8	1701	Q7Z7M0
FCPDIYPAPTSDLWP	GARIN5A	121	Q6IPT2
NPLIPWDYCPISRCE	HGF	456	P14210
RNPDEDPRGPWCYVS	PIK3IP1	71	Q96FE7
DCYVQLWLPTASPSP	PLA2G4F	66	Q68DD2
RDRAWGYCVEATPPP	HGFAC	141	Q04756
CNILAWVPSLYEPVP	ERCC8	356	Q13216
YPGWFLCTVPEADQP	IL36RN	116	Q9UBH0
PCTELVPWAAEPGYL	PCDHB12	571	Q9Y5F1
YRPTWDLALDPLVSC	RNF144A	6	P50876
AWFECETSIPSVRPP	OBSCN	2396	Q5VST9
SLWIPPAFGCRPEYD	OTOP1	556	Q7RTM1
AEPHPLWEYPCRSLS	PRMT7	561	Q9NVM4
PSFLLRYDDLCLPWA	CPNE7	161	Q9UBL6
RALPPPCSCAWYFSL	TMEM30B	86	Q3MIR4
CRPPSDSTQVPCWLY	MCEMP1	66	Q8IX19
WDVLTPDPNSCPPLY	DENND4B	1351	O75064
YAERWGLEPCTLPVI	KNDC1	1196	Q76NI1
AKCWDPTPRSYFTVP	DVL1	336	O14640
AKCWDPTPRSYFTVP	DVL1P1	336	P54792
RYACSSSEDWPPPLD	BEAN1	111	Q3B7T3
EWPFPDLFSEPLCRG	CREB3	326	O43889
KIETDYWPCPPSLAV	DMTN	186	Q08495
ACCPLWFPLIYDDPV	SLC17A4	241	Q9Y2C5
RCGWSPAEELNYTVP	SLC22A1	61	O15245
GLCSPELWKEVRYPP	NYNRIN	71	Q9P2P1
RLQWECPPESLSFDP	PACRGL	101	Q8N7B6
TALVEVWSPDRCCPY	OTOG	2626	Q6ZRI0
FAWCPLETSSRPEEP	P2RX5	166	Q93086
VWLCSYGRPPAARPT	GRIN3B	961	O60391
CPAAGIPPVTLRWYL	DSCAM	46	O60469
STEDCVRWPSLLAPY	PARS2	356	Q7L3T8
PETPPSWSCQEKLYS	SYNDIG1L	26	A6NDD5
CEALTEWEYLPPVGP	USP9X	1536	Q93008
YLASDPDCRWCPAPD	RNF19B	196	Q6ZMZ0
ACPDPSLSVWRPDIY	POLR1A	1141	O95602
IPYTSVEDFDWCTPP	SMCHD1	481	A6NHR9
LCDPNRLPPYLRWCV	MELTF	356	P08582
RLPPYLRWCVLSTPE	MELTF	361	P08582
LCPLYRPGEWEDLAS	NCOA7	301	Q8NI08
WTIPPDPRNECYLAL	SAMD9L	1236	Q8IVG5
PDYPRQSIKETPCWI	SMAD4	511	Q13485
EWSSDTAEGRPCPYP	RNF43	746	Q68DV7
WYGPRSPLLCPERQE	RUFY4	131	Q6ZNE9
PLPRTIWDGEETSYC	SIX1	116	Q15475
DCVLARDPYCAWSPP	SEMA4D	511	Q92854
RDPYCAWSPPTATCV	SEMA4D	516	Q92854
NPDRELRPWCFTTDP	PLG	236	P00747
TTGCLIPPAYEPWRE	STXBP5	866	Q5T5C0
AYWPDRSDTEVPPLD	FAM83F	106	Q8NEG4
CKECTYPRPLPSDWI	SPRY2	186	O43597
YPRPLPSDWICDKQC	SPRY2	191	O43597
PWCFYPNTIDVPPEE	TFF1	66	P04155
SRCPRLPELEEFPWT	ABTB2	86	Q8N961
VGPWRTYDFCPLECP	TECTA	971	O75443
AWPPPSYESISLALD	TMEM61	171	Q8N0U2
VCDWLYPLVPDRSPV	SPART	271	Q8N0X7
DVSRPYPEPGWEAKC	WFDC12	86	Q8WWY7
CSPEWPRKLVSYCPR	GGCX	311	P38435
KCWDYRHEPPRLAPL	nan	31	Q6ZSR6
RTLPPSPNWYCARCS	GEMIN5	6	Q8TEQ6
YPSPWPEKFPAIERC	XRN1	611	Q8IZH2
YPALCSPRVPPRCWA	PRRT4	621	C9JH25
PLPRSIWDGEETSYC	SIX2	116	Q9NPC8
EPPVVCSYFARDLWP	ZNF492	41	Q9P255
DPPLSSVPSEDEWYC	UHRF1	346	Q96T88
SEECYWSPLSHPLPE	TTC7A	296	Q9ULT0
CPWLTRAVSPAVPVY	ZDHHC8	36	Q9ULC8
SFQYPLPWSECPVVR	SLC6A17	171	Q9H1V8
SLPEQQEPAWRIPYC	ZC3H12C	811	Q9C0D7
SIALCWEVPDGPYPQ	PTPRH	401	Q9HD43
PAAGEDWQCPRTPYA	MST1R	21	Q04912
WTPDECIPEFYTDPS	WDR81	486	Q562E7
VRYRAAPWEPPCGLT	TPCN2	111	Q8NHX9
DLIFSCWPEPSAPLQ	NLRP12	266	P59046
SYRCQPGVLLPVWEP	SLC8A2	46	Q9UPR5
WEEPSPRDRAPLTYS	MYOM3	521	Q5VTT5