Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmannosyltransferase activity

DPY19L2 DPY19L1 DPY19L2P2

8.42e-0528613GO:0000030
GeneOntologyBiologicalProcesspeptidyl-tryptophan modification

DPY19L2 DPY19L1 DPY19L2P2

5.14e-076623GO:0018211
GeneOntologyBiologicalProcessprotein C-linked glycosylation via tryptophan

DPY19L2 DPY19L1 DPY19L2P2

5.14e-076623GO:0018317
GeneOntologyBiologicalProcessprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

DPY19L2 DPY19L1 DPY19L2P2

5.14e-076623GO:0018406
GeneOntologyBiologicalProcessprotein C-linked glycosylation

DPY19L2 DPY19L1 DPY19L2P2

5.14e-076623GO:0018103
GeneOntologyBiologicalProcessprotein mannosylation

DPY19L2 DPY19L1 DPY19L2P2

5.67e-0525623GO:0035268
GeneOntologyBiologicalProcessmannosylation

DPY19L2 DPY19L1 DPY19L2P2

6.40e-0526623GO:0097502
GeneOntologyBiologicalProcessdiencephalon morphogenesis

SOX2 OTX2

1.32e-046622GO:0048852
GeneOntologyBiologicalProcessRNA 5'-end processing

CMTR1 RPP40 UTP20

2.02e-0438623GO:0000966
GeneOntologyCellularComponentstereocilium tip

MYO3A CDH23 PKHD1L1

3.33e-0522603GO:0032426
GeneOntologyCellularComponentphotoreceptor inner segment

MYO3A CDH23 PRPH2 DRAM2

7.46e-0578604GO:0001917
DomainGamma_tubulin

TUBG2 TUBG1

1.01e-052602IPR002454
DomainDpy19

DPY19L2 DPY19L1

6.06e-054602PF10034
DomainDpy-19/Dpy-19-like

DPY19L2 DPY19L1

6.06e-054602IPR018732
DomainBax_inhibitor_1-related

GRINA FAIM2

1.51e-046602IPR006214
DomainHEAT_REPEAT

SCYL2 SMG1 UTP20

1.48e-0370603PS50077
Domain-

TUBG2 TUBG1

1.86e-03206023.30.1330.20
Domain-

TUBG2 TUBG1

2.05e-03216021.10.287.600
DomainTubulin_C

TUBG2 TUBG1

2.25e-0322602SM00865
DomainTubulin_C

TUBG2 TUBG1

2.25e-0322602PF03953
DomainTubulin/FtsZ_2-layer-sand-dom

TUBG2 TUBG1

2.25e-0322602IPR018316
Domain-

TUBG2 TUBG1

2.25e-03226023.40.50.1440
DomainTubulin_C

TUBG2 TUBG1

2.46e-0323602IPR023123
DomainTUBULIN

TUBG2 TUBG1

2.46e-0323602PS00227
DomainTubulin

TUBG2 TUBG1

2.46e-0323602IPR000217
DomainTub_FtsZ_C

TUBG2 TUBG1

2.46e-0323602IPR008280
DomainTubulin

TUBG2 TUBG1

2.46e-0323602SM00864
DomainTubulin_CS

TUBG2 TUBG1

2.46e-0323602IPR017975
DomainTubulin_FtsZ_GTPase

TUBG2 TUBG1

2.68e-0324602IPR003008
DomainTubulin

TUBG2 TUBG1

2.68e-0324602PF00091
DomainARM-type_fold

SCYL2 SMG1 XPO6 UTP20 RYR3

4.62e-03339605IPR016024
Pubmed

Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus.

SOX2 OTX2 TUBG2 TUBG1

1.64e-081662434815315
Pubmed

Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway.

SOX2 OTX2 TUBG2 TUBG1

3.48e-081962429166577
Pubmed

Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models.

SOX2 OTX2 TUBG2 TUBG1

4.34e-082062433382037
Pubmed

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

SOX2 TUBG2 TUBG1

5.38e-08562321529752
Pubmed

AIRE is a critical spindle-associated protein in embryonic stem cells.

SOX2 TUBG2 TUBG1

1.88e-07762328742026
Pubmed

The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.

SOX2 OTX2 TUBG2 TUBG1

4.60e-073562428402857
Pubmed

Primary cilia are critical for tracheoesophageal septation.

SOX2 TUBG2 TUBG1

8.81e-071162337776236
Pubmed

Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin.

SOX2 TUBG2 TUBG1

1.17e-061262322318628
Pubmed

Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells.

SOX2 TUBG2 TUBG1

1.17e-061262323918393
Pubmed

Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

SOX2 TUBG2 TUBG1

1.52e-061362326903504
Pubmed

Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding.

SOX2 TUBG2 TUBG1

1.52e-061362328231465
Pubmed

Ikaros family proteins redundantly regulate temporal patterning in the developing mouse retina.

SOX2 OTX2 NFIA

1.94e-061462336537580
Pubmed

Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis.

SOX2 TUBG2 TUBG1

2.42e-061562326369386
Pubmed

Phosphorylated β-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain.

SOX2 TUBG2 TUBG1

2.97e-061662321736876
Pubmed

Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant.

SOX2 TUBG2 TUBG1

2.97e-061662326579598
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

3.13e-06262228119396
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

3.13e-06262217442887
Pubmed

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.

DPY19L2 DPY19L2P2

3.13e-06262222764053
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

3.13e-06262222806905
Pubmed

Gene knockout analysis of two gamma-tubulin isoforms in mice.

TUBG2 TUBG1

3.13e-06262215893303
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

3.13e-06262217287496
Pubmed

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.

DPY19L2 DPY19L2P2

3.13e-06262225354700
Pubmed

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.

DPY19L2 DPY19L2P2

3.13e-06262225354701
Pubmed

EPO regulates neuroprotective Transmembrane BAX Inhibitor-1 Motif-containing (TMBIM) family members GRINA and FAIM2 after cerebral ischemia-reperfusion injury.

GRINA FAIM2

3.13e-06262231211943
Pubmed

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.

SOX2 TUBG2 TUBG1

6.02e-062062334237032
Pubmed

Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.

DPY19L2 DPY19L1 DPY19L2P2

6.02e-062062322028030
Pubmed

Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape.

SOX2 TUBG2 TUBG1

7.01e-062162325114215
Pubmed

ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.

OTX2 TUBG2 TUBG1

7.01e-062162338402586
Pubmed

Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche.

TUBG2 TUBG1 IL6ST

7.01e-062162325127137
Pubmed

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.

SOX2 TUBG2 TUBG1

9.31e-062362318728187
Pubmed

DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.

SOX2 TUBG2 TUBG1

9.31e-062362330329130
Pubmed

The gamma-tubulin gene family in humans.

TUBG2 TUBG1

9.37e-06362210903841
Pubmed

SOX2, OTX2 and PAX6 analysis in subjects with anophthalmia and microphthalmia.

SOX2 OTX2

9.37e-06362225542770
Pubmed

Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope.

DPY19L2 DPY19L2P2

9.37e-06362225775128
Pubmed

Targeted 'next-generation' sequencing in anophthalmia and microphthalmia patients confirms SOX2, OTX2 and FOXE3 mutations.

SOX2 OTX2

9.37e-06362222204637
Pubmed

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

TUBG2 TUBG1

9.37e-06362227015882
Pubmed

Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

TUBG2 TUBG1

9.37e-0636229566969
Pubmed

Duplication and relocation of the functional DPY19L2 gene within low copy repeats.

DPY19L2 DPY19L2P2

9.37e-06362216526957
Pubmed

Morphology, GluR1 and GRIP-C localization differ in octopus cells of C57BL6 and B6Cast mice.

GRIP1 CDH23

9.37e-06362212204345
Pubmed

Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2.

SOX2 OTX2

9.37e-06362216712695
Pubmed

The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.

TUBG2 TUBG1

9.37e-06362226021315
Pubmed

Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development.

OTX2 TUBG2 TUBG1

1.06e-052462335322202
Pubmed

Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity.

SOX2 TUBG2 TUBG1

1.21e-052562334932949
Pubmed

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

SOX2 TUBG2 TUBG1

1.53e-052762326158450
Pubmed

Loss of Necdin impairs myosin activation and delays cell polarization.

TUBG2 TUBG1

1.87e-05462220665884
Pubmed

Cilia organize ependymal planar polarity.

TUBG2 TUBG1

1.87e-05462220164345
Pubmed

Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.

TUBG2 TUBG1

1.87e-05462236574677
Pubmed

Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging.

KL CHRM1

1.87e-05462223389690
Pubmed

FoxO transcription factors actuate the formative pluripotency specific gene expression programme.

SOX2 OTX2

1.87e-05462239251582
Pubmed

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.

TUBG2 TUBG1

1.87e-05462216798874
Pubmed

Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.

SOX2 TUBG2 TUBG1

2.34e-053162330305289
Pubmed

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.

SOX2 TUBG2 TUBG1

2.83e-053362330914320
Pubmed

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

SOX2 TUBG2 TUBG1

2.83e-053362330626697
Pubmed

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.

TUBG2 TUBG1

3.12e-05562221285373
Pubmed

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation.

TUBG2 TUBG1

3.12e-05562229244804
Pubmed

Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.

TUBG2 TUBG1

3.12e-05562231390572
Pubmed

FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice.

DPY19L2 DPY19L2P2

3.12e-05562234471926
Pubmed

IL-6 amplifier, NF-κB-triggered positive feedback for IL-6 signaling, in grafts is involved in allogeneic rejection responses.

EGF IL6ST

3.12e-05562222798669
Pubmed

A two-kinesin mechanism controls neurogenesis in the developing brain.

TUBG2 TUBG1

3.12e-05562238040957
Pubmed

Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.

TUBG2 TUBG1

3.12e-05562216751367
Pubmed

A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos.

TUBG2 TUBG1

3.12e-05562215680357
Pubmed

Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.

TUBG2 TUBG1

3.12e-05562219251731
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

TUBG2 TUBG1

3.12e-05562218729223
Pubmed

Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases.

SOX2 OTX2

3.12e-05562220494911
Pubmed

WDR62 is associated with the spindle pole and is mutated in human microcephaly.

TUBG2 TUBG1

3.12e-05562220890279
Pubmed

Speriolin is a novel human and mouse sperm centrosome protein.

TUBG2 TUBG1

3.12e-05562220542897
Pubmed

Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.

TUBG2 TUBG1

3.12e-05562225877302
Pubmed

HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.

TUBG2 TUBG1

3.12e-05562214767062
Pubmed

Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4.

SOX2 CDH23

3.12e-05562231722212
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

OTX2 TUBG2 TUBG1

3.39e-053562337890489
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

CHRM1 RYR3

4.67e-05662219549818
Pubmed

Comparative genomics and function analysis on BI1 family.

GRINA FAIM2

4.67e-05662218440869
Pubmed

The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP.

TUBG2 TUBG1

4.67e-05662238546045
Pubmed

Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor.

TUBG2 TUBG1

4.67e-05662230970247
Pubmed

Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development.

TUBG2 TUBG1

4.67e-05662235259752
Pubmed

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis.

TUBG2 TUBG1

4.67e-05662222842144
Pubmed

Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis.

TUBG2 TUBG1

4.67e-05662229229864
Pubmed

Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton.

TUBG2 TUBG1

4.67e-05662210840040
Pubmed

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.

TUBG2 TUBG1

4.67e-05662236334595
Pubmed

A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity.

TUBG2 TUBG1

4.67e-05662211237715
Pubmed

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.

GRINA FAIM2

4.67e-05662225764978
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

SOX2 TUBG2 TUBG1

5.08e-054062332317081
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

FLT3 TUBG1 SNX2

5.89e-054262329348145
Pubmed

Experimental analysis of the emergence of left-right asymmetry of the body axis in early postimplantation mouse embryos.

SOX2 OTX2

6.53e-05762210512182
Pubmed

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis.

TUBG2 TUBG1

6.53e-05762229724823
Pubmed

Primate gastrulation and early organogenesis at single-cell resolution.

SOX2 OTX2

6.53e-05762236517595
Pubmed

Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.

TUBG2 TUBG1

6.53e-05762222902295
Pubmed

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

GRIP1 GRIA3

6.53e-05762217093100
Pubmed

PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting.

TUBG2 TUBG1

6.53e-05762238827526
Pubmed

Mammalian RanBP1 regulates centrosome cohesion during mitosis.

TUBG2 TUBG1

6.53e-05762212840069
Pubmed

TMEM216 promotes primary ciliogenesis and Hedgehog signaling through the SUFU-GLI2/GLI3 axis.

TUBG2 TUBG1

6.53e-05762238261656
Pubmed

The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.

TUBG2 TUBG1

6.53e-05762229372668
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

TUBG2 TUBG1

6.53e-05762230289203
Pubmed

Pax6 controls centriole maturation in cortical progenitors through Odf2.

TUBG2 TUBG1

6.53e-05762225352170
Pubmed

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells.

SOX2 TUBG2 TUBG1

7.75e-054662325182747
Pubmed

Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development.

SOX2 TUBG2 TUBG1

8.27e-054762339001875
Pubmed

A ciliopathy complex builds distal appendages to initiate ciliogenesis.

TUBG2 TUBG1

8.69e-05862234241634
Pubmed

Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.

TUBG2 TUBG1

8.69e-05862227727273
Pubmed

A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.

TUBG2 TUBG1

8.69e-05862217908927
Pubmed

The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex.

TUBG2 TUBG1

8.69e-05862219112494
Cytoband13q12

FLT3 KL

4.86e-042462213q12
GeneFamilyTransmembrane BAX inhibitor motif containing

GRINA FAIM2

6.76e-0563921215
GeneFamilyTubulins

TUBG2 TUBG1

1.43e-0326392778
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIP1 DNAH10 PTCHD4 PKHD1L1 RYR3

2.71e-06160615c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIP1 DNAH10 PTCHD4 PKHD1L1 RYR3

2.71e-0616061525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRIP1 RHPN2 C2 HACD4 PKHD1L1

4.81e-061806152ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.10e-06189615f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellMatrixFB-Fibroblast-C|MatrixFB / shred on cell class and cell subclass (v4)

GRIP1 C2 FAIM2 PKHD1L1 IL6ST

6.26e-06190615d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.26e-0619061556cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.26e-0619061525d4b591f75c26e404a34c42f1742d580af6598d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.42e-061916157b386512284dfaa0e95358b28ee82632ee965e64
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KL TTC21A CTSH PKHD1L1 IL6ST

6.58e-0619261514a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KL TTC21A CTSH PKHD1L1 IL6ST

6.58e-06192615847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.92e-0619461552aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

6.92e-06194615bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST HACD4 CTSH

7.10e-061956150fcc41cda3e5f921748cf7e7fe48dd7ca1de4636
ToppCellnormal-na-Myeloid-conventional_dendritic_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST HACD4 CTSH

7.46e-0619761517c6d2a7baef6393c3e2d3e65cc924df22049eb0
ToppCellnormal-na-Myeloid-conventional_dendritic_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST HACD4 CTSH

7.46e-061976159a0bcb055b1a5fd5439e4a0bf1742f009331df47
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST HACD4 CTSH

7.64e-06198615b0e090000d1cdee4628f4ab252f6b444658f80f5
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST HACD4 CTSH

7.64e-0619861599f98e240d81cfe5b485da2598f8392d7cbd9013
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-B-B_memory|COVID-19_Convalescent / Disease, condition lineage and cell class

TTC21A DRAM2 CTSH PKHD1L1 SNX2

7.83e-061996155bbda86486910d053ca51b9caee487d78f6462cb
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 GRIP1 EGF RHPN2 NFIA

8.02e-06200615682960e28542a3d6c119047cd0131941932cfdea
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRIP1 EGF RHPN2 SLCO1A2 SLC1A2

8.02e-06200615030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

8.02e-06200615862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

8.02e-06200615a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX2 GRIP1 MYO3A PTCHD4 IL6ST

8.02e-06200615d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 GRIP1 EGF RHPN2 SLCO1A2

8.02e-0620061585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GRIP1 FLT3 RXFP3 PTCHD4

2.70e-0512661484dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST DNAH10

5.77e-0515361491e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST DNAH10

5.77e-05153614f17f62646633cf95c810dcd5328978058741b276
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST CTSH

6.07e-05155614ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST CTSH

6.07e-051556149a27558c457f05808af07190b7a5006b047f1d58
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS13A P2RY8 GRIA3 CRTC1

7.03e-05161614d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBG2 KLHL15 CDH23 HACD4

7.38e-051636147a04192710f55acf5a4681d5f09942358fdb02ff
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

SOX2 DST HACD4 CTSH

7.38e-05163614d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 C2 CTSH SLC1A2

7.55e-05164614b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 C2 CTSH SLC1A2

7.55e-051646143aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT3 RASGRF1 P2RY8 CTSH

8.29e-051686146dd58fd981750da49afd53796f244e1803cce97f
ToppCellControl-Epithelial_alveolar-Mes-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RPP40 KLHL15 HACD4 TUBG1

8.29e-051686143c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

KL RASGRF1 CRTC1 SLC2A13

8.29e-0516861400646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellControl-Epithelial_alveolar-Mes-like-AT1_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RPP40 KLHL15 HACD4 TUBG1

8.29e-0516861449180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KL DPY19L1 NFIA RYR3

8.29e-051686147abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GRIP1 FLT3 SLC2A13 PTCHD4

8.48e-0516961478eb70dd916724e476eabccf18fb7fcec4210308
ToppCelldroplet-Lung-nan-21m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 EGF CDH23 RYR3

8.88e-05171614159ce6d5513008532dd7785b915b3fe7440cc4b2
ToppCelldroplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 FLT3 RASGRF1 DPY19L1

9.29e-051736141b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCelldroplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 FLT3 RASGRF1 DPY19L1

9.29e-05173614c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA CTSH FAIM2 IL6ST

9.50e-05174614cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CMTR1 RASGRF1 TUBG2 DIS3L

9.71e-0517561478a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 C2 PKHD1L1 RYR3

9.71e-05175614f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIP1 RHPN2 C2 HACD4

9.92e-051766148e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIP1 RHPN2 C2 HACD4

9.92e-05176614ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KL DPY19L1 NFIA RYR3

9.92e-0517661472a2a01618ce836bc843395d5095e9090759b4a6
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

SMG1 DST DPY19L2 CMTR1

9.92e-051766143de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KL DPY19L1 NFIA RYR3

1.04e-04178614431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRIP1 C2 HACD4 PKHD1L1

1.04e-041786141e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MYO3A DPY19L1 RYR3

1.04e-04178614a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HIVEP3 EGF CDH23 RYR3

1.06e-041796144f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 EGF CDH23 RYR3

1.06e-04179614d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KL DPY19L2 EGF PTCHD4

1.06e-04179614666072c0e8448dbaec1683d18368ec2502453f90
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASGRF1 CTSH PKHD1L1 SNX2

1.06e-04179614fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 FLT3 GRIA3 CTSH

1.11e-04181614782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 FLT3 GRIA3 CTSH

1.11e-04181614e2481291c236105774c53883e6f20da11941df9b
ToppCellImmune_cells-Dendritic_cells|Immune_cells / Lineage and Cell class

FLT3 RASGRF1 GRIA3 CTSH

1.13e-0418261499c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KL DPY19L2 EGF PTCHD4

1.15e-041836142e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 CHRM1 PKHD1L1 RYR3

1.18e-041846142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 CHRM1 PKHD1L1 RYR3

1.18e-04184614ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 CHRM1 PKHD1L1 RYR3

1.18e-041846142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRIP1 C2 HACD4 PKHD1L1

1.18e-04184614607b55022de21ddb6a2d75e085df76df7abf6624
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 C2 PKHD1L1 RYR3

1.20e-04185614bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 MYO3A PTCHD4 IL6ST

1.23e-04186614310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_naive|COVID-19_Convalescent / Disease group, lineage and cell class

GARIN4 TTC21A DRAM2 SNX2

1.23e-041866149d339f57036d17572882ebb801f2be9b1d1ddc1c
ToppCellMultiple_Sclerosis-Lymphocyte-B-B_memory|Multiple_Sclerosis / Disease, Lineage and Cell Type

DRAM2 CTSH PKHD1L1 SNX2

1.28e-041886148da631b2c75441b7309f03e7d4c14f15f2367be6
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST CTSH

1.28e-041886148431991e68b8e9c5eb72212460f6da679ea3b85a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4

1.28e-041886148268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST CTSH

1.28e-04188614d8f10b3ad11bc99a63f44560e39791085256e5c8
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASGRF1 CTSH PKHD1L1 SNX2

1.28e-04188614b6ae707b033a17c75ca81f9194631ead1b63d170
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 GRIP1 VPS13A SLC1A2

1.28e-04188614beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KL CTSH PKHD1L1 IL6ST

1.31e-041896148e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST CTSH

1.31e-04189614c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 MYO3A PTCHD4

1.31e-04189614222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCellMultiple_Sclerosis-Lymphocyte-B|Multiple_Sclerosis / Disease, Lineage and Cell Type

DRAM2 CTSH PKHD1L1 SNX2

1.31e-04189614864f666b1e8557a689320075036920e3ac589b8b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRIP1 MYO3A RHPN2 GRIA3

1.31e-0418961428b502611829e4a24caff2562545c7db97686099
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST CTSH

1.31e-04189614807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KL CTSH PKHD1L1 IL6ST

1.31e-04189614fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellremission-B_memory|remission / disease stage, cell group and cell class

TTC21A CTSH PKHD1L1 SNX2

1.31e-04189614a7b434a5d2cc7c3952cb8f16d11219b691c6c2b6
ToppCell390C-Lymphocytic-B_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DRAM2 CTSH PKHD1L1 SNX2

1.33e-04190614f63c9474f23bb72f0bb1fc531342f0da04ed8b3e
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GRIP1 FLT3 DST CTSH

1.33e-041906144b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCellremission-B_memory|World / disease stage, cell group and cell class

RASGRF1 TTC21A CTSH SNX2

1.33e-04190614c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

FLT3 RASGRF1 CTSH SLC1A2

1.33e-0419061415978ddd37b521343f88b62dad1643077fc22b2b
ToppCell390C-Lymphocytic-B_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DRAM2 CTSH PKHD1L1 SNX2

1.33e-0419061453bf211f0e8a44f5adb89c43b210a1e35120b6a8
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST CTSH

1.36e-041916146cda82a994f4b205cf54590c979d7c9f3be2b4c8
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST CTSH

1.36e-041916144257f02856f3510981e9f84d465d91448d6126e2
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 GRIP1 MYO3A SLC1A2

1.36e-0419161439220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRIP1 FLT3 DST CTSH

1.36e-041916142699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCellB_cell_maturation-Memory_B_cell|World / Lineage and Cell class

DRAM2 CTSH PKHD1L1 SNX2

1.36e-04191614528c3dea44238233dc1aa8d6ba5c3a191d18d985
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRIP1 FLT3 DST CTSH

1.36e-041916144b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_memory|COVID-19_Convalescent / Disease group, lineage and cell class

DRAM2 CTSH PKHD1L1 SNX2

1.36e-041916144a853cd2434b0f5b18e1f853c37515845046c88b
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

TTC21A DRAM2 CTSH SNX2

1.36e-0419161407b03739db24c7d834300de63ef1847724cba684
ToppCell10x5'-bone_marrow-Lymphocytic_B-Memory_B_cells|bone_marrow / Manually curated celltypes from each tissue

RASGRF1 DRAM2 CTSH SNX2

1.36e-0419161467479df0ca4c5a792fd604aded3f75609fec0888
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIP1 MYO3A PTCHD4 IL6ST

1.36e-04191614fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KL CDH23 IL6ST RYR3

1.39e-04192614eafead22bba48ac5ee568faa8946c444445c1034
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 GRIP1 PTCHD4 IL6ST

1.39e-04192614f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TTC21A C2 HACD4 CTSH

1.39e-04192614935a4a36881a9fa4daa02cba96af07f6686ed8d6
DrugGAMs

GRIA3 GRINA CTSH OPRL1

3.21e-0638614CID000002935
Druggeldanamycin

SCYL2 SCRN3 DST EGF GRIA3 SLC2A13 CCNK IL6ST

6.39e-06371618ctd:C001277
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

4.07e-062602DOID:0090138 (implicated_via_orthology)
DiseaseButterfly-shaped pigmentary macular dystrophy

OTX2 PRPH2

1.22e-053602C4511237
DiseaseDisorder of eye

SOX2 GRIP1 OTX2 CDH23 PRPH2

7.23e-05212605C0015397
DiseaseMICROPHTHALMIA, ISOLATED 1

SOX2 OTX2

8.48e-057602C1855052
DiseaseSepto-Optic Dysplasia

SOX2 OTX2

8.48e-057602C0338503
DiseaseMicrophthalmos, Autosomal Recessive

SOX2 OTX2

8.48e-057602C4551977
Diseasemyeloid white cell count

HIVEP3 FLT3 EGF DNAH10 NFIA SUPT5H XPO6 CDH23 SNX2

1.09e-04937609EFO_0007988
Diseasehealth literacy measurement

SMG1 UTP20 SLC1A2

1.74e-0453603EFO_0010104
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CDH23 CTSH

2.65e-0412602EFO_0801493
DiseaseColorectal Carcinoma

HIVEP3 KL RHPN2 SLCO1A2 VPS13A CTSH IL6ST

5.42e-04702607C0009402
DiseaseAnophthalmia-microphthalmia syndrome

SOX2 OTX2

8.33e-0421602cv:C5680330
Diseaseprogranulin measurement

GRIP1 CDH23

9.15e-0422602EFO_0004625
DiseaseHypermetropia

HIVEP3 RASGRF1 NFIA

1.22e-03103603HP_0000540
DiseaseKallmann Syndrome

SOX2 OTX2

1.28e-0326602C0162809
Diseasemacular degeneration (is_implicated_in)

PRPH2 C2

1.38e-0327602DOID:4448 (is_implicated_in)
Diseaseresponse to corticosteroid

DST PTCHD4

1.59e-0329602GO_0031960
Diseasesuicidal ideation

GRIP1 CDH23

1.59e-0329602EFO_0004320
DiseaseCone-Rod Dystrophy 2

PRPH2 DRAM2

1.59e-0329602C3489532
DiseaseEpileptic encephalopathy

SLC1A2 RYR3

1.71e-0330602C0543888

Protein segments in the cluster

PeptideGeneStartEntry
GYKTFSTSMMLLTVY

COX14

11

Q96I36
STSMMLLTVYGGYLC

COX14

16

Q96I36
VSSMSMTAQYYKTSD

C2orf78

156

A6NCI8
MTAQYYKTSDTNTMV

C2orf78

161

A6NCI8
YVVGSSYENELMLMS

COPZ2

111

Q9P299
SSYMSGEGYQSLQSM

CCNK

436

O75909
LDYETKTSYMMNVSA

CDH23

1271

Q9H251
SSSYYSMSPGAMRRS

NFIA

251

Q12857
VAFYANMYSSILTMT

P2RY8

101

Q86VZ1
ASLSYMVGMIASFYN

GRINA

236

Q7Z429
TLSMAYLTGMLSSYY

FAIM2

176

Q9BWQ8
MVRYTYSMLSVIGIS

HACD4

126

Q5VWC8
LSYLMINSYMDANTG

DST

1991

Q03001
LLPYYTAQSGSSMSM

GARIN4

6

Q8IYT1
GTNTYAALNSVYLMM

C2

336

P06681
IFGFYDQMSMNTLTS

GRIA3

101

P42263
MGSLYMFVQTILSYQ

DRAM2

131

Q6UX65
MFGNSMLLTSYYASS

DPY19L1

301

Q2PZI1
YGSAISMYMKTQSKS

OR13H1

251

Q8NG92
SMYLSSYYSSSLLMT

DPY19L2

391

Q6NUT2
FSYSQIVSSLMGMSS

OR7D4

216

Q8NG98
LTMAYVSSGSYSYMT

FCSK

316

Q8N0W3
NYFEMSTYSTNRTMI

FLT3

296

P36888
SLTSDTLYMVRMAAY

IL6ST

581

P40189
LQFMYYGTIELSMNT

KLHL15

86

Q96M94
TDYGTLLSQQMGMVY

EGF

501

P01133
YSPGSTLNYSQAAMM

CRTC1

521

Q6UUV9
MATQAMSNALYFSTG

DIS3L

761

Q8TF46
LGTRAMVYYMSTTII

SLC1A2

116

P43004
TFSMNLYTTYLLMGH

CHRM1

76

P11229
TQDFMMYRTGIYSST

CTSH

256

P09668
TMNEPYTRNMTYSAG

KL

686

Q9UEF7
SMSAYSLSSLNMGTL

GRIP1

411

Q9Y3R0
VLSEMALVNSMYQYS

DNAH10

3661

Q8IVF4
SSRYSMYNSVSQKLM

CMTR1

81

Q8N1G2
SMYLSSYYSSSLLMT

DPY19L2P2

201

Q6ZN68
TSSSCMQRSYPMTYT

OTX2

166

P32243
YYNMFTSTFTLTAMS

OPRL1

131

P41146
TGSEESTMMSYFSKY

RPP40

186

O75818
INTIMYYSATILQMS

SLC2A13

341

Q96QE2
VTSMNMYASVFFLTA

RXFP3

161

Q9NSD7
DMSSIYSMYSTLLAH

UTP20

166

O75691
MNAYMAYRVTTKTSL

SNX2

156

O60749
TSSQTYMNGSPTYSM

SOX2

211

P48431
SYLDTAKMMTSSGRY

SCRN3

226

Q0VDG4
DAYSDVMVTYTMTSS

PTCHD4

331

Q6ZW05
VMVTYTMTSSLYFIT

PTCHD4

336

Q6ZW05
SYARSTAVMSMVGYI

SMG1

2316

Q96Q15
ASDMYSLGTVMYAVF

SCYL2

246

Q6P3W7
VSKTLSGSYMNSMLT

SLCO1A2

31

P46721
MTSTYGRTPMYGSQT

SUPT5H

761

O00267
GYTSMYSAMSPFSKA

RASGRF1

781

Q13972
TYSVGMQKTYSMICL

RHPN2

606

Q8IUC4
KMVSYMDATAGSAYT

VPS13A

1126

Q96RL7
MSASTTTLRYPGYMN

TUBG1

236

P23258
RAALLSYYSSLMNSM

PRPH2

251

P23942
SYYSSLMNSMGVVTL

PRPH2

256

P23942
LYTSYSSMMAKSCQS

RYR3

3576

Q15413
NMPSYGSAMYTTLSQ

HIVEP3

1326

Q5T1R4
SATYSVGMQKTYSMI

RHPN2P1

501

A8MT19
PTMTNQYSVTMTSYN

PKHD1L1

871

Q86WI1
MSSNDSSLMAGIIYY

TTC21A

1

Q8NDW8
GTSLMYVALNMTSAS

SLC35F6

101

Q8N357
MSASTTTLRYPGYMN

TUBG2

236

Q9NRH3
FLSSTRNDYVMMYSL

XPO6

51

Q96QU8
MKTQTVASYFRYSLM

MYO3A

921

Q8NEV4