Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II complex binding

NCOA3 SCAF4

4.38e-0439162GO:0000993
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

NCOA3 SCAF4

5.84e-0445162GO:0043175
GeneOntologyMolecularFunctionRNA polymerase binding

NCOA3 SCAF4

1.22e-0365162GO:0070063
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

NCOA3 SCAF4

1.25e-0366162GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

NCOA3 SCAF4

1.25e-0366162GO:0001098
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MYT1L NCOA3 MAML3 SYNE2 TNRC6A

1.67e-031160165GO:0030674
GeneOntologyMolecularFunctiontranscription coactivator activity

MYT1L NCOA3 MAML3

1.67e-03303163GO:0003713
GeneOntologyMolecularFunctionmolecular adaptor activity

MYT1L NCOA3 MAML3 SYNE2 TNRC6A

3.33e-031356165GO:0060090
GeneOntologyMolecularFunctiontranscription coregulator activity

MYT1L NCOA3 MAML3

9.45e-03562163GO:0003712
MousePhenodecreased brown fat cell size

NCOA3 ADCY3

8.33e-0515132MP:0009136
MousePhenoabnormal brown fat cell size

NCOA3 ADCY3

1.08e-0417132MP:0009135
DomainRRM

SCAF4 ENOX1 TNRC6A

6.35e-04217153SM00360
DomainRRM_dom

SCAF4 ENOX1 TNRC6A

7.24e-04227153IPR000504
DomainRRM

SCAF4 ENOX1 TNRC6A

7.52e-04230153PS50102
Domain-

SCAF4 ENOX1 TNRC6A

8.92e-042441533.30.70.330
DomainNucleotide-bd_a/b_plait

SCAF4 ENOX1 TNRC6A

1.05e-03258153IPR012677
DomainUBA-like

UBQLN1 TNRC6A

1.18e-0364152IPR009060
DomainRRM_1

SCAF4 ENOX1

1.18e-02208152PF00076
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML3 MAMLD1

2.48e-0510112MM15535
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 MAMLD1

3.64e-0512112M27159
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML3 MAMLD1

5.01e-0514112M27808
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

MAML3 MAMLD1

6.60e-0516112M27121
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML3 MAMLD1

8.41e-0518112MM14775
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

MAML3 MAMLD1 TNRC6A

9.21e-05119113M607
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 MAMLD1

1.04e-0420112M27881
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

MAML3 MAMLD1

1.39e-0423112MM14954
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 MAMLD1

1.64e-0425112M27880
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

MAML3 MAMLD1

2.07e-0428112M6177
PathwayREACTOME_SIGNALING_BY_NOTCH2

MAML3 MAMLD1

2.88e-0433112M604
PathwayREACTOME_SIGNALING_BY_NOTCH

MAML3 MAMLD1

4.04e-0439112MM14604
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

MAML3 MAMLD1

4.69e-0442112M17541
PathwayWP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY

ADCY3 SYNE2

5.62e-0446112M39828
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 MAMLD1

6.12e-0448112M611
PathwayREACTOME_SIGNALING_BY_NOTCH3

MAML3 MAMLD1

6.38e-0449112M618
PathwayREACTOME_SIGNALING_BY_NOTCH

MAML3 MAMLD1 TNRC6A

7.81e-04246113M10189
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

MAML3 MAMLD1

8.93e-0458112M29616
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

MAML3 MAMLD1

1.26e-0369112M46439
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML3 MAMLD1

1.45e-0374112M616
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML3 MAMLD1

1.53e-0376112MM15520
PathwayREACTOME_SIGNALING_BY_NOTCH4

MAML3 MAMLD1

1.78e-0382112M594
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

NCOA3 TNRC6A

2.28e-0393112M27572
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML3 MAMLD1

2.43e-0396112M27784
PathwayREACTOME_GASTRULATION

MAML3 MAMLD1

4.33e-03129112M46433
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

NCOA3 MAML3 TNRC6A

1.41e-07231639225980
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOA3 MAML3 ZNF609 MAMLD1 TNRC6A

1.49e-0645716532344865
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

ADCY3 SYNE2 UBQLN1 MAMLD1

1.20e-0532216426514267
Pubmed

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

SYNE2 UBQLN1

3.02e-051816233361760
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA3 ZNF609 TNRC6A

4.40e-0515216338360978
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

MAML3 MAMLD1

6.41e-052616224391519
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NCOA3 ZNF609 TNRC6A

7.27e-0518016335198878
Pubmed

ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB.

SCAF4 UBQLN1

1.86e-044416234839354
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

NCOA3 SYNE2

2.90e-045516218570454
Pubmed

Human transcription factor protein interaction networks.

NCOA3 ZNF609 SYNE2 SCAF4 TNRC6A

3.47e-04142916535140242
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MYT1L NCOA3 ZNF609 TES

4.21e-0480816420412781
InteractionNUP35 interactions

NCOA3 MAML3 ZNF609 MAMLD1 TNRC6A

1.45e-05424165int:NUP35
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 MAML3 TNRC6A

6.62e-0725133775
GeneFamilyRNA binding motif containing

SCAF4 ENOX1

9.89e-03213132725
CoexpressionKRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP

BMP2K NCOA3 MAML3 TES SCAF4

5.33e-05778155M17915
CoexpressionLINDGREN_BLADDER_CANCER_CLUSTER_2A_DN

BMP2K TES UBQLN1

6.61e-05141153M11896
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

SYNE2 ENOX1 MAMLD1

2.09e-051531634ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3 MAMLD1

2.57e-05164163b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3 MAMLD1

2.86e-05170163876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3 MAMLD1

2.86e-051701631f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF609 SYNE2 TNRC6A

4.11e-05192163e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

TLR9 ENOX1 MAN2B1

4.24e-05194163768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BMP2K NCOA3 MAN2B1

4.24e-05194163d852aebf7a763b9a776c4570711f0c759f591910
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MAML3 ZNF609 TNRC6A

4.57e-0519916394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAMLD1

1.19e-03144162cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAMLD1

1.19e-0314416241eaeca54b3c39de417597267cbdb1f195dd885a
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

SYNE2 ENOX1

1.23e-03147162baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES TLR9

1.27e-03149162a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

SYNE2 ENOX1

1.32e-03152162451745151322c2fcea22dbb3dba681e12634a510
ToppCellPND28-Immune-Immune_Myeloid-DC-maDC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP2K TES

1.34e-03153162b03375c54aa701817c0fc2c3fef32b870169e697
ToppCellPND28-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP2K TES

1.34e-0315316218bd770a18e642581a6df144d47184c1ac383713
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K MAML3

1.37e-03155162231fbbbd6e6f9c86be7a15a9ec0804e6b9ab3b5f
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

BMP2K MAML3

1.39e-03156162bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

SYNE2 ENOX1

1.39e-03156162afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

BMP2K MAML3

1.39e-03156162159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 MAMLD1

1.42e-031581625775246e192629058ed89fb56031bdf4cbb9c15c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.44e-031591625ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE2

1.44e-03159162bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCOA3 SYNE2

1.50e-031621623e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF609 SCAF4

1.51e-03163162d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.53e-0316416243630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.53e-0316416246208f18325976c89f572f6627aea0582142b92d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.53e-03164162108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BMP2K MAML3

1.55e-03165162640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BMP2K MAML3

1.55e-0316516237615622c736e43260c38016e7c9e565ac97a3e8
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY3 MAN2B1

1.55e-031651624e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BMP2K MAML3

1.55e-03165162f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

TES MAN2B1

1.59e-03167162cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR9 MAN2B1

1.61e-0316816259b698f58cb206f0f8f0e8ad72b445d14ba24728
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K MAN2B1

1.63e-03169162b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCell343B-Myeloid-Dendritic-cDC_activated|343B / Donor, Lineage, Cell class and subclass (all cells)

BMP2K ENOX1

1.63e-031691622098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BMP2K MAN2B1

1.63e-031691622322f03a115c662f808ebfc892192b7d38d48181
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

BMP2K MAML3

1.64e-03170162e90f18e5462381b38e918442b38b1c8105291908
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TLR9 MAN2B1

1.64e-031701626ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

BMP2K ENOX1

1.64e-031701624ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYT1L ADCY3

1.64e-031701625570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

ADCY3 ENOX1

1.66e-03171162080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|390C / Donor, Lineage, Cell class and subclass (all cells)

TES SYNE2

1.66e-03171162d6d8ea45b443d95f64720c9bc07d324148f5b239
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MYT1L SYNE2

1.66e-03171162d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE2

1.66e-03171162e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE2

1.66e-03171162e6dfbd2652b67577c8834c05348f62150637f348
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE2

1.66e-03171162ddaeb96ce9c9c3bf232b4a42266fa2ee7e8f3f41
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

PGBD3 SYNE2

1.66e-031711626be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.68e-0317216208a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TLR9 MAN2B1

1.68e-03172162c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

BMP2K ENOX1

1.68e-031721621b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAML3

1.68e-03172162553701349444eb366df3c11f54bb093434f153c6
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K MAN2B1

1.70e-031731624e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCellmild_COVID-19_(asymptomatic)-gd_T|World / disease group, cell group and cell class (v2)

MYT1L SYNE2

1.70e-03173162b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ADCY3 MAN2B1

1.70e-03173162efb8072475000888efe088d00e870c56ffad4172
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY3 ENOX1

1.72e-03174162015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES TLR9

1.72e-031741627565f6d1c743809807d248ab0e098a2474d9c5b9
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES MAN2B1

1.72e-03174162c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

PGBD3 ENOX1

1.72e-031741625ec8a48a390379d6c422120dce46437a77da67cc
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP2K ENOX1

1.72e-0317416216204ff504b7b382b4d90ca35003ad5336020e07
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K MAN2B1

1.72e-03174162dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CD24|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAML3 MAMLD1

1.72e-031741623e29d620b7b4ab1915ddac70ee5a50d09072292b
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADCY3 MAN2B1

1.72e-0317416258300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K MAN2B1

1.72e-0317416254166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY3 MAMLD1

1.72e-031741621d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES ENOX1

1.72e-03174162ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCellfacs-Heart-LV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K MAN2B1

1.74e-031751625d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

TES MAN2B1

1.74e-03175162c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 MAN2B1

1.76e-03176162d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 MAN2B1

1.76e-031761624f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 MAN2B1

1.76e-031761620afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

BMP2K MAML3

1.76e-03176162473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

PGBD3 ENOX1

1.76e-03176162b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 MAMLD1

1.80e-03178162d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K TES

1.82e-031791621b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K TES

1.82e-0317916251872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L MAML3

1.82e-0317916269a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MAML3 ENOX1

1.82e-0317916214fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L MAML3

1.82e-03179162479116ac65488c60104a053530830763ec1f95b2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L MAML3

1.82e-031791621dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAML3 MAN2B1

1.84e-03180162810c7116007ee6668d3731e7ce1fcf697c7b24f6
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADCY3 ENOX1

1.86e-0318116233cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY3 ENOX1

1.86e-03181162451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

BMP2K ENOX1

1.86e-031811626252184ef098b911df50be4fe1b5565849a5b6b8
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

BMP2K ENOX1

1.86e-03181162982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCellfacs-Lung-EPCAM-24m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES MAN2B1

1.88e-031821629465238ac806fce46dfe1a141e83893f23eb4afb
ToppCellT_cells-Resident_memory_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ADCY3 MAMLD1

1.88e-03182162111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MAML3 ENOX1

1.88e-031821627b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY3 ENOX1

1.90e-031831628a799807fbf24456a9811e0c64068187940a2f71
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

ADCY3 ENOX1

1.90e-03183162fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K TES

1.90e-03183162919c9861073d12fd12aecd7469b1478b13838c43
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 TNRC6A

1.90e-03183162f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

BMP2K ENOX1

1.90e-03183162bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 TNRC6A

1.92e-031841625350b58aa9979631228835d11eb45ddf81d08bff
ToppCellfacs-Lung-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TES MAN2B1

1.92e-03184162c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY3 ENOX1

1.92e-03184162689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellT_cells-Resident_memory_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ADCY3 MAMLD1

1.92e-03184162e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY3 ENOX1

1.92e-03184162327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BMP2K SCAF4

1.94e-03185162e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

ADCY3 ENOX1

1.94e-031851624905adaeeffd353e089578e5ea614437dbe794e6
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP2K TES

1.94e-0318516219fa853f6f746ccf232a343b3c9c7a5e55800409
DrugAustricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A

ADCY3 ZNF609 TES SCAF4

9.12e-061971642812_DN
DrugEconazole nitrate [24169-02-6]; Up 200; 9uM; MCF7; HT_HG-U133A

BMP2K ZNF609 TES

2.87e-041881637427_UP
DrugProtoveratrine A [143-57-7]; Down 200; 5uM; MCF7; HT_HG-U133A

ADCY3 ZNF609 SCAF4

2.91e-041891632800_DN
DrugCanrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A

BMP2K ADCY3 ZNF609

3.10e-041931636783_DN
DrugGSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A

BMP2K NCOA3 SCAF4

3.10e-041931637097_UP
DrugChlorhexidine [55-56-1]; Up 200; 8uM; HL60; HG-U133A

NCOA3 TES SCAF4

3.19e-041951632025_UP
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

ADCY3 ZNF609 SCAF4

3.19e-04195163999_DN
Drug2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A

BMP2K ADCY3 ZNF609

3.19e-041951631665_DN
DrugRibostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; HL60; HT_HG-U133A

ADCY3 ZNF609 SCAF4

3.19e-041951632705_DN
DrugPancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A

ZNF609 SYNE2 SCAF4

3.19e-041951634393_DN
DrugNorethynodrel [68-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A

NCOA3 ZNF609 SCAF4

3.19e-041951631818_UP
DrugAzlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A

BMP2K ADCY3 ZNF609

3.19e-041951632727_DN
DrugCholecalciferol [67-97-0]; Down 200; 10.4uM; HL60; HT_HG-U133A

BMP2K NCOA3 ZNF609

3.24e-041961632436_DN
DrugTrapidil [15421-84-8]; Down 200; 19.4uM; HL60; HT_HG-U133A

NCOA3 ADCY3 ZNF609

3.24e-041961633136_DN
DrugPiretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.24e-041961633567_DN
Drugsodium 4-phenylbutyrate; Up 200; 1000uM; HL60; HG-U133A

NCOA3 ZNF609 TES

3.24e-04196163411_UP
DrugDomperidone maleate; Down 200; 7.4uM; HL60; HT_HG-U133A

BMP2K ADCY3 MAN2B1

3.24e-041961631301_DN
DrugIsoniazid [54-85-3]; Up 200; 29.2uM; HL60; HG-U133A

NCOA3 ZNF609 TES

3.24e-041961631399_UP
DrugTubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; HL60; HG-U133A

MAML3 ZNF609 SCAF4

3.24e-041961631738_UP
DrugDroperidol [548-73-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.24e-041961634629_DN
DrugPerphenazine [58-39-9]; Down 200; 10uM; MCF7; HT_HG-U133A

BMP2K ADCY3 ZNF609

3.29e-041971631540_DN
DrugPindolol [13523-86-9]; Down 200; 16.2uM; HL60; HG-U133A

ZNF609 TES SCAF4

3.29e-041971631392_DN
DrugBerberine chloride [633-65-8]; Up 200; 10.8uM; HL60; HG-U133A

NCOA3 MAML3 ZNF609

3.29e-041971631778_UP
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; HL60; HG-U133A

NCOA3 ZNF609 TES

3.29e-041971631385_UP
DrugKetorolac tromethamine [74103-07-4]; Down 200; 10.6uM; PC3; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.29e-041971637286_DN
DrugLobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; HL60; HG-U133A

ADCY3 ZNF609 SCAF4

3.29e-041971631747_DN
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A

BMP2K ADCY3 SCAF4

3.34e-041981634367_DN
DrugAvermectin B1 [71751-41-2]; Down 200; 4.8uM; PC3; HT_HG-U133A

BMP2K SYNE2 SCAF4

3.34e-041981635864_DN
DrugDimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A

ADCY3 SCAF4 MAMLD1

3.34e-041981634791_DN
DrugUrosiol [128-13-2]; Up 200; 10.2uM; PC3; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.34e-041981637243_UP
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A

BMP2K ZNF609 TES

3.39e-041991633264_UP
DrugCefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; PC3; HT_HG-U133A

NCOA3 ZNF609 SCAF4

3.39e-041991637148_DN
DrugNorfloxacin [70458-96-7]; Up 200; 12.6uM; HL60; HG-U133A

BMP2K MAML3 TES

3.39e-041991631406_UP
DrugSB 202190; Up 200; 1uM; PC3; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.39e-041991637058_UP
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

BMP2K ZNF609 SCAF4

3.39e-041991631804_UP
DrugClindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A

ADCY3 SCAF4 MAMLD1

3.39e-041991632057_DN
DrugDesipramine hydrochloride [58-28-6]; Up 200; 13.2uM; HL60; HG-U133A

BMP2K MAML3 ZNF609

3.39e-041991631596_UP
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HG-U133A

BMP2K NCOA3 ZNF609

3.44e-042001631939_UP
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

ADCY3 MAML3 TNRC6A

9.25e-04364163EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasedepressive symptom measurement, response to antidepressant

MYT1L ADCY3

1.03e-0388162EFO_0007006, GO_0036276
Diseasevisceral adipose tissue measurement

ADCY3 MAML3 TNRC6A

2.06e-03481163EFO_0004765
Diseasebody fat percentage

ADCY3 MAML3 TNRC6A

2.14e-03488163EFO_0007800
Diseasesmoking status measurement

MYT1L ADCY3 MAML3 TNRC6A

2.96e-031160164EFO_0006527
Diseaseunipolar depression, bipolar disorder

SYNE2 ENOX1

3.17e-03156162EFO_0003761, MONDO_0004985
DiseaseC-reactive protein measurement

ADCY3 MAML3 TES SCAF4

3.41e-031206164EFO_0004458
Diseasewaist-hip ratio

ADCY3 MAML3 SYNE2 TNRC6A

3.61e-031226164EFO_0004343

Protein segments in the cluster

PeptideGeneStartEntry
MMPQYQQAFFQQQML

BMP2K

536

Q9NSY1
MNNYLPQNHMNMINQ

MAML3

566

Q96JK9
NNQSFNNFMLRIGMN

ADCY3

1031

O60266
SFLLQQMMQQPQRFQ

MAMLD1

611

Q13495
IMNMNQQLLLPVRQT

MAN2B1

626

O00754
QNMDQFQPRMMGIQQ

SCAF4

336

O95104
QFLQQTMQGMQQQLL

ENOX1

471

Q8TC92
QVQQPNMIKVYNQFM

PGBD3

446

Q8N328
PVQNQALARQYMQML

TES

116

Q9UGI8
MDNLMIPFQQYQQVS

SYNE2

3756

Q8WXH0
ARPVLQQQQQMLQMR

NCOA3

971

Q9Y6Q9
PMLQTLRLQMNFINQ

TLR9

391

Q9NR96
RQLIMANPQMQQLIQ

UBQLN1

206

Q9UMX0
QEQMRQQLPTFLQQM

UBQLN1

431

Q9UMX0
QQPSVIQQRPNMYMQ

ZNF609

956

O15014
QQMMQQSRQLDPNLL

TNRC6A

1451

Q8NDV7
MSPQQQAVMNNRCFQ

MYT1L

796

Q9UL68