Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

PITPNM2 DSC3 DSG2 SPTA1 FSTL5 PCLO FSTL4 SHH PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 PKD1L2 FLG2 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 DHH CELSR2 HMCN1 ACAN VCAN PCDH19 IHH CDH10 CDH12

3.31e-1574916733GO:0005509
GeneOntologyMolecularFunctioncholesterol-protein transferase activity

SHH DHH IHH

5.75e-0731673GO:0140853
GeneOntologyMolecularFunctionpatched binding

SHH DHH IHH

3.12e-0581673GO:0005113
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7L AKR7A3

2.07e-0431672GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7L AKR7A3

2.07e-0431672GO:0019118
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 PTPRF CELSR2 HMCN1 PCDH19 CDH10 CDH12

1.43e-1418716718GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 TENM2 FAT1 FAT2 PTPRF CELSR2 HMCN1 PCDH19 CDH10 CDH12

1.02e-1131316719GO:0098742
GeneOntologyBiologicalProcesscell-cell adhesion

EPHB4 ZBTB16 DSC3 DSG2 SPTA1 SRF SHH PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 SIRPB1 TENM2 FAT1 FAT2 PTPRF CELSR2 HMCN1 ICAM5 PCDH19 TMEM131L PDE5A DLG4 IHH CDH10 CDH12 CNTN1

6.22e-10107716731GO:0098609
GeneOntologyBiologicalProcessprotein splicing

SHH DHH IHH

5.21e-0731673GO:0030908
GeneOntologyBiologicalProcessintein-mediated protein splicing

SHH DHH IHH

5.21e-0731673GO:0016539
GeneOntologyCellularComponentsynapse-associated extracellular matrix

TNC LAMA5 ACAN VCAN

2.59e-06131664GO:0099535
GeneOntologyCellularComponentbasement membrane

TNC LAMA5 FREM3 FREM2 PXDN HMCN1 ACAN

5.46e-051221667GO:0005604
GeneOntologyCellularComponentperisynaptic extracellular matrix

TNC ACAN VCAN

7.74e-05111663GO:0098966
GeneOntologyCellularComponentexcitatory synapse

PCLO GRIN2B C1QL2 PTPRF KCNJ9 DLG4

2.14e-041071666GO:0060076
GeneOntologyCellularComponentcollagen-containing extracellular matrix

TNC RBP3 SHH LAMA5 FREM3 F13A1 BMP1 FREM2 PXDN HMCN1 ACAN VCAN CSPG4

3.27e-0453016613GO:0062023
GeneOntologyCellularComponentextracellular matrix

TNC RBP3 SHH LAMA5 FREM3 F13A1 BMP1 FREM2 PXDN HMCN1 ACAN VCAN CSPG4 IHH

7.70e-0465616614GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TNC RBP3 SHH LAMA5 FREM3 F13A1 BMP1 FREM2 PXDN HMCN1 ACAN VCAN CSPG4 IHH

7.93e-0465816614GO:0030312
GeneOntologyCellularComponentextrinsic component of plasma membrane

CDH23 TENM2 CRKL DLG4 CDH10 CDH12

7.99e-041371666GO:0019897
GeneOntologyCellularComponentinterphotoreceptor matrix

RBP3 VCAN

9.21e-0461662GO:0033165
DomainCadherin

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FREM3 KIAA0319 FREM2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

6.42e-1911816519IPR002126
DomainCA

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FREM2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

2.18e-1611516517SM00112
DomainCadherin_CS

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

1.93e-1510916516IPR020894
DomainCADHERIN_1

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

3.48e-1511316516PS00232
DomainCadherin

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

3.48e-1511316516PF00028
DomainCADHERIN_2

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

4.02e-1511416516PS50268
Domain-

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

4.02e-15114165162.60.40.60
DomainCadherin-like

DSC3 DSG2 PCDHA13 CDH23 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT1 FAT2 CELSR2 PCDH19 CDH10 CDH12

5.34e-1511616516IPR015919
DomainCadherin_tail

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.05e-08371657PF15974
DomainCadherin_CBD

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.05e-08371657IPR031904
DomainCadherin_2

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 PCDH19

1.03e-07651658PF08266
DomainCadherin_N

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 PCDH19

1.03e-07651658IPR013164
DomainEGF-like_CS

EPHB4 TNC LAMA5 ADAM12 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

5.80e-0726116513IPR013032
DomainHedgehog_signalling_dom

SHH DHH IHH

6.77e-0731653IPR000320
DomainHintN

SHH DHH IHH

6.77e-0731653SM00306
DomainHintC

SHH DHH IHH

6.77e-0731653SM00305
DomainHedgehog

SHH DHH IHH

6.77e-0731653IPR001657
DomainHH_signal

SHH DHH IHH

6.77e-0731653PF01085
DomainHint

SHH DHH IHH

6.77e-0731653PF01079
DomainHedgehog_sig/DD-Pept_Zn-bd_dom

SHH DHH IHH

6.77e-0731653IPR009045
DomainHint_dom

SHH DHH IHH

6.77e-0731653IPR001767
Domain-

SHH DHH IHH

6.77e-07316533.30.1380.10
DomainHint_dom_N

SHH DHH IHH

6.77e-0731653IPR003587
DomainHint_dom_C

SHH DHH IHH

6.77e-0731653IPR003586
DomainEGF_2

EPHB4 TNC LAMA5 ADAM12 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

6.89e-0726516513PS01186
DomainLaminin_G_2

LAMA5 NELL1 FAT1 FAT2 CELSR2 CSPG4

1.30e-06401656PF02210
DomainEGF_CA

TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

1.37e-061221659SM00179
DomainEGF-like_Ca-bd_dom

TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

1.57e-061241659IPR001881
DomainEGF-like_dom

TNC LAMA5 ADAM12 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

2.25e-0624916512IPR000742
DomainLamG

LAMA5 NELL1 FAT1 FAT2 CELSR2 CSPG4

2.32e-06441656SM00282
DomainHedgehog/Intein_dom

SHH DHH IHH

2.69e-0641653IPR028992
Domain-

SHH DHH IHH

2.69e-06416532.170.16.10
DomainEGF_1

TNC LAMA5 ADAM12 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

2.89e-0625516512PS00022
DomainEGF

TNC LAMA5 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

7.96e-0623516511SM00181
DomainEGF_3

TNC ADAM12 TENM2 LDLR BMP1 NELL1 FAT1 FAT2 CELSR2 HMCN1 VCAN

7.96e-0623516511PS50026
DomainGrowth_fac_rcpt_

EPHB4 TNC LAMA5 LDLR BMP1 NELL1 FAT1 CELSR2 HMCN1

1.04e-051561659IPR009030
DomainLaminin_G

LAMA5 NELL1 FAT1 FAT2 CELSR2 CSPG4

1.20e-05581656IPR001791
DomainLAM_G_DOMAIN

LAMA5 FAT1 FAT2 CELSR2 CSPG4

2.01e-05381655PS50025
Domain-

NBEAL1 LAMA5 NELL1 FAT1 FAT2 CELSR2 CSPG4

2.13e-059516572.60.120.200
DomainASX_HYDROXYL

LDLR BMP1 NELL1 FAT1 CELSR2 HMCN1 VCAN

2.97e-051001657PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LDLR BMP1 NELL1 FAT1 CELSR2 HMCN1 VCAN

4.33e-051061657IPR000152
DomainIg_I-set

SPEG FSTL5 FSTL4 IGSF22 PXDN PTPRF HMCN1 ICAM5 CNTN1

4.94e-051901659IPR013098
DomainI-set

SPEG FSTL5 FSTL4 IGSF22 PXDN PTPRF HMCN1 ICAM5 CNTN1

4.94e-051901659PF07679
DomainCadherin_C

DSC3 DSG2 CDH10 CDH12

6.43e-05251654PF01049
DomainCadherin_cytoplasmic-dom

DSC3 DSG2 CDH10 CDH12

6.43e-05251654IPR000233
DomainINTEIN_N_TER

SHH IHH

7.76e-0521652PS50817
DomainIntein_N

SHH IHH

7.76e-0521652IPR006141
DomainCatenin_binding_dom

DSC3 DSG2 CDH10 CDH12

1.17e-04291654IPR027397
Domain-

DSC3 DSG2 CDH10 CDH12

1.17e-042916544.10.900.10
DomainEGF

TNC BMP1 FAT1 FAT2 CELSR2 HMCN1 VCAN

1.29e-041261657PF00008
DomainEGF_Ca-bd_CS

LDLR BMP1 NELL1 FAT1 HMCN1 VCAN

2.21e-04971656IPR018097
DomainEGF_CA

LDLR BMP1 NELL1 FAT1 HMCN1 VCAN

2.47e-04991656PS01187
DomainIGc2

SPEG FSTL5 FSTL4 IGSF22 PXDN PTPRF HMCN1 ICAM5 CNTN1

2.48e-042351659SM00408
DomainIg_sub2

SPEG FSTL5 FSTL4 IGSF22 PXDN PTPRF HMCN1 ICAM5 CNTN1

2.48e-042351659IPR003598
DomainPP2A_PR55_CS

PPP2R2B PPP2R2C

4.60e-0441652IPR018067
DomainPP2A_PR55

PPP2R2B PPP2R2C

4.60e-0441652IPR000009
DomainPR55_2

PPP2R2B PPP2R2C

4.60e-0441652PS01025
DomainPR55_1

PPP2R2B PPP2R2C

4.60e-0441652PS01024
DomainFd_Rdtase_FAD-bd

POR NOX3 NOS1

5.91e-04191653IPR017927
DomainFAD_FR

POR NOX3 NOS1

5.91e-04191653PS51384
DomainRiboflavin_synthase-like_b-brl

POR NOX3 NOS1

5.91e-04191653IPR017938
Domain-

COPA NBEAL1 FSTL5 FSTL4 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

7.74e-04333165102.130.10.10
DomainWD40/YVTN_repeat-like_dom

COPA NBEAL1 FSTL5 FSTL4 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

8.10e-0433516510IPR015943
DomainQuino_amine_DH_bsu

FSTL5 FSTL4 TENM2

9.22e-04221653IPR011044
DomainEGF_CA

LDLR BMP1 NELL1 FAT1 HMCN1

9.91e-04861655PF07645
DomainFAD_binding_1

POR NOS1

1.14e-0361652PF00667
Domain-

POR NOS1

1.14e-03616521.20.990.10
DomainPKD/REJ-like

PKD1L2 KIAA0319

1.14e-0361652IPR002859
DomainFAD-binding_1

POR NOS1

1.14e-0361652IPR003097
DomainREJ

PKD1L2 KIAA0319

1.14e-0361652PF02010
DomainNADPH_Cyt_P450_Rdtase_dom3

POR NOS1

1.14e-0361652IPR023173
DomainFN3

EPHB4 TNC SPEG KIAA0319 IGSF22 PTPRF CNTN1

1.30e-031851657SM00060
DomainIG

SPEG FSTL5 FSTL4 SIRPB1 IGSF22 PXDN PTPRF HMCN1 ICAM5 VCAN CNTN1

1.32e-0342116511SM00409
DomainIg_sub

SPEG FSTL5 FSTL4 SIRPB1 IGSF22 PXDN PTPRF HMCN1 ICAM5 VCAN CNTN1

1.32e-0342116511IPR003599
DomainIg-like_fold

EPHB4 TNC SPEG FSTL5 FSTL4 SIRPB1 F13A1 KIAA0319 IGSF22 PXDN PTPRF HMCN1 ICAM5 VCAN CNTN1

1.52e-0370616515IPR013783
DomainDesmosomal_cadherin

DSC3 DSG2

1.58e-0371652IPR009122
DomainFlavodoxin/NO_synth

POR NOS1

2.10e-0381652IPR008254
DomainFlavdoxin-like

POR NOS1

2.10e-0381652IPR001094
DomainCalx_beta

FREM3 FREM2

2.10e-0381652SM00237
DomainFLAVODOXIN_LIKE

POR NOS1

2.10e-0381652PS50902
DomainFlavodoxin_1

POR NOS1

2.10e-0381652PF00258
DomainWD40

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

2.17e-032591658PF00400
Domain-

EPHB4 TNC SPEG FSTL5 FSTL4 SIRPB1 F13A1 IGSF22 PXDN PTPRF HMCN1 ICAM5 VCAN CNTN1

2.30e-03663165142.60.40.10
DomainFN3_dom

EPHB4 TNC SPEG KIAA0319 IGSF22 PTPRF CNTN1

2.60e-032091657IPR003961
DomainWD40

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

2.68e-032681658SM00320
DomainCalx_beta

FREM3 FREM2

2.68e-0391652IPR003644
DomainCalx-beta

FREM3 FREM2

2.68e-0391652PF03160
DomainWD40_repeat

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

2.93e-032721658IPR001680
Domainfn3

EPHB4 TNC SPEG IGSF22 PTPRF CNTN1

3.20e-031621656PF00041
Domain-

POR NOS1

3.33e-031016523.40.50.360
DomainFlavoprotein-like_dom

POR NOS1

3.33e-03101652IPR029039
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

POR NOS1

3.33e-03101652IPR001709
DomainWD_REPEATS_1

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

3.35e-032781658PS00678
DomainConA-like_dom

NBEAL1 LAMA5 NELL1 FAT1 FAT2 CELSR2 CSPG4

3.37e-032191657IPR013320
DomainWD40_repeat_CS

COPA THOC6 PPP2R2B CFAP52 DAW1 DCAF12

3.40e-031641656IPR019775
DomainWD_REPEATS_2

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

3.42e-032791658PS50082
DomainWD_REPEATS_REGION

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

3.42e-032791658PS50294
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION

SHH DHH IHH

1.04e-0561153M47892
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

SHH DHH IHH

1.81e-0571153MM15187
PathwayREACTOME_LIGAND_RECEPTOR_INTERACTIONS

SHH DHH IHH

1.81e-0571153MM15224
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

SHH DHH IHH

2.87e-0581153M27444
PathwayREACTOME_LIGAND_RECEPTOR_INTERACTIONS

SHH DHH IHH

2.87e-0581153M27496
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

SHH DHH IHH

4.29e-0591153M47893
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY

SHH DHH IHH

1.80e-04141153M47414
PathwayREACTOME_ACTIVATION_OF_SMO

SHH DHH IHH

1.80e-04141153MM15228
PathwayWP_HEDGEHOG_SIGNALING_WP47

SHH DHH IHH

2.74e-04161153M39675
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.52e-1315169715640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.05e-1217169729911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.72e-1218169715570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.72e-1218169710662547
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

MAN2A1 DSG2 TNC SHH SIRPB1 LDLR F13A1 APOM FREM2 FAT2 PTPRF ACAN CSPG4 IHH CNTN1

2.73e-122571691516335952
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.82e-1124169724698270
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

6.13e-1128169715347688
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT2 CELSR2

7.98e-1172169910380929
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT2 CELSR2

1.48e-1077169910835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 FAT2 CELSR2

2.10e-1080169910716726
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4

1.15e-091116959655502
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 TTC28 SPEG FSTL5 PEG3 CSMD3 VIRMA TENM2 MADD KIAA0319 PXDN PCDH19 ACIN1 SPEN ARHGAP21

1.68e-094071691512693553
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 TENM2

3.37e-0975169815372022
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DOCK4 PITPNM2 EPRS1 PPFIA2 PCLO ACBD5 ATG2B HIP1R PSMC1 POR GRIN2B PFKL TENM2 MADD CRKL LONP1 RBSN CELSR2 AKR7L AKR7A3 DLG4 AKT2 NOS1

8.45e-0911391692336417873
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.22e-0857169732633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.38e-0858169730377227
Pubmed

Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.

TNC SHH DHH VCAN IHH

2.81e-0819169528202523
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.27e-0868169711230163
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.73e-0874169710817752
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 PITPNM2 SPEG CYB561D2 HIP1R LAMA5 LDLR MADD FAT1 IGF2R MDN1 PTPRF CELSR2 CSPG4 USP40 DIAPH2 AKT2 SPEN ARHGAP21 ABTB2 RAD9A

1.10e-0711051692135748872
Pubmed

PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain.

GRIN2B DLG4 NOS1

1.13e-073169310488080
Pubmed

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.

SHH DHH IHH

1.13e-073169319074837
Pubmed

Evolution of the hedgehog gene family.

SHH DHH IHH

1.13e-07316938849902
Pubmed

Hedgehog signal transduction: from flies to vertebrates.

SHH DHH IHH

1.13e-073169310579908
Pubmed

A new role for Hedgehogs in juxtacrine signaling.

SHH DHH IHH

1.13e-073169324342078
Pubmed

[Hedgehog signaling pathway and its impact on development of cancer therapy].

SHH DHH IHH

1.13e-073169318788453
Pubmed

The hedgehog signaling pathway in the mouse ovary.

SHH DHH IHH

1.13e-073169317392501
Pubmed

The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.

SHH DHH IHH

1.13e-073169318063705
Pubmed

The world according to hedgehog.

SHH DHH IHH

1.13e-07316939009843
Pubmed

Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway.

GRIN2B DLG4 NOS1

1.13e-073169333962017
Pubmed

Comparative biological responses to human Sonic, Indian, and Desert hedgehog.

SHH DHH IHH

1.13e-073169311472839
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA13 PCDHA7 PCDHA6 PCDHA4

2.58e-0712169410612399
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 FOXRED1 ZBTB38 WASHC4 COPA TTC28 USP11 PEG3 POLR1C PSMC1 MSH3 GRIN2B EYA3 MADD PPP4R3B NELL1 SBNO1 AHCY DLG4 DHX35 ATM ARHGAP21

3.19e-0712851692235914814
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EPHB4 MAN2A1 COPA DSG2 FSTL4 PSMC1 LAMA5 ADAM12 LDLR MADD BMP1 FAT1 IGF2R PXDN PTPRF CELSR2 CSPG4 TMEM131L ATM ARHGAP21 DCAF12

4.31e-0712011692135696571
Pubmed

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.

SHH DHH IHH

4.49e-07416937916661
Pubmed

Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.

SHH DHH IHH

4.49e-07416939053312
Pubmed

Ligand binding to the PDZ domains of postsynaptic density protein 95.

GRIN2B DLG4 NOS1

4.49e-074169326941280
Pubmed

Scaffolding protein Homer1a protects against NMDA-induced neuronal injury.

GRIN2B DLG4 NOS1

4.49e-074169326247728
Pubmed

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 ADAM12 RANBP17

4.81e-07193169922589738
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 EPRS1 COPA TNC PPFIA2 SPTA1 PCLO RBP3 PSMC1 POR GRIN2B PFKL IDH3B VIRMA MADD LONP1 PPP2R2C ICAM5 VCAN DLG4 NOS1 ARHGAP21 CNTN1

5.04e-0714311692337142655
Pubmed

A protein interaction landscape of breast cancer.

DOCK4 TTC28 DSG2 ZG16B HIP1R MSH3 THOC6 LONP1 IGF2R MDN1 AHCY PYCR1 ACIN1 AKT2 ARHGAP21

5.53e-076341691534591612
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

DOCK4 GRIN2B TENM2 PPP2R2B RBSN PCDH19 PYCR1 DLG4 NOS1

5.72e-07197169936604605
Pubmed

Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells.

SHH DHH IHH

1.12e-065169319559697
Pubmed

Hedgehog and patched gene expression in adult ocular tissues.

SHH DHH IHH

1.12e-06516939237688
Pubmed

All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.

SHH DHH IHH

1.12e-065169320519495
Pubmed

Expression of NG2 proteoglycan during endochondral and intramembranous ossification.

TNC VCAN CSPG4

1.12e-065169312950088
Pubmed

Developmental pathways in breast cancer and breast tumor-initiating cells: therapeutic implications.

SHH DHH IHH

1.12e-065169322123293
Pubmed

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.

SHH DHH IHH

1.12e-065169310050855
Pubmed

Products, genetic linkage and limb patterning activity of a murine hedgehog gene.

SHH DHH IHH

1.12e-06516937720571
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SIRPB1 GRIN2B BCOR VIRMA TENM2 SPICE1 KIAA0319 IGF2R MDN1 CELSR2 ICAM5 DIAPH2 DLG4 NOS1 ARHGAP21 CDH10 WNK3 CNTN1

1.20e-069631691828671696
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SNX4 WASHC4 DSG2 ACBD5 ATG2B POR MADD PRKD3 RBSN IGF2R DIAPH2 TMEM131L SMCR8

1.26e-065041691334432599
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

DSG2 TNC CYB561D2 ACBD5 POR NUBP1 SIRPB1 F13A1 SPICE1 HENMT1 PPP2R2B FAT1 MDN1 CEP95 ETHE1 VCAN CSPG4 DLG4 CSMD1 SMCR8 IP6K2

1.40e-0612931692115342556
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMA5 FREM3 FREM2 CSPG4

1.56e-0618169414730302
Pubmed

Sonic hedgehog is required for vascular outgrowth in the hindbrain choroid plexus.

SHH DHH CSPG4 IHH

1.56e-0618169420123094
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

TNC LAMA5 F13A1 FREM2 PXDN HMCN1 VCAN CSPG4

1.73e-06167169822159717
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.00e-06119169728625976
Pubmed

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.

SHH DHH IHH

2.23e-066169320978073
Pubmed

Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.

SHH DHH IHH

2.23e-06616937589793
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

EPRS1 COPA USP11 CDH23 MSH3 VCAN DIAPH2 SGO2 WNK3

2.46e-06235169930258100
Pubmed

Characterization of two patched receptors for the vertebrate hedgehog protein family.

SHH DHH IHH

3.89e-06716939811851
Pubmed

Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.

PTPRF ACAN VCAN

3.89e-067169321976490
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SHH DHH IHH

3.89e-067169325639508
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2B DLG4 NOS1

6.20e-068169317360663
Pubmed

Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis.

TNC ACAN IHH

6.20e-068169317336282
Pubmed

Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.

SHH DHH IHH

6.20e-068169310529434
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

SHH IGF2R ACAN VCAN

6.28e-0625169429475039
Pubmed

Superresolution imaging of chemical synapses in the brain.

PCLO GRIN2B DLG4

9.27e-069169321144999
Pubmed

Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.

SHH DHH IHH

9.27e-069169325842978
Pubmed

Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4.

SHH DHH IHH

9.27e-069169317881493
Pubmed

Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation.

SHH DHH IHH

9.27e-069169320570969
Pubmed

Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

DSC3 DSG2 FAT1

1.32e-0510169312724416
Pubmed

Development of migrating tendon-bone attachments involves replacement of progenitor populations.

TNC SHH IHH

1.32e-0510169330504126
Pubmed

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.

SHH DHH IHH

1.32e-0510169321652647
Pubmed

Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo.

SHH DHH IHH

1.32e-0510169311311154
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

LAMA5 PKD1L2 CSMD3 CSMD1 DCAF12

1.43e-0563169511572484
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

SPEG FSTL4 PXDN PTPRF HMCN1 ICAM5 CNTN1

1.53e-05162169725826454
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TTC28 TNC MUC16 IDH3B BCOR VIRMA PPP2R2B MDN1 PYCR1 HFM1 SMCR8 SPEN FAM149A

1.59e-056381691331182584
Pubmed

Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development.

SHH DHH IHH

1.81e-0511169317028112
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

SHH ACAN VCAN

1.81e-0511169338750698
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

DSC3 DSG2 FREM2 PTPRF CELSR2

1.93e-0567169521875946
Pubmed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

ERCC5 MUC16 MSH3 F13A1 IGF2R AKT2 ATM

2.09e-05170169719064572
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 COPA DSG2 PCLO PSMC1 POR MSH3 PFKL IDH3B CRKL LONP1 IGF2R MDN1 SBNO1 AHCY PYCR1 ACIN1 SGO2 ATM SPEN

2.15e-0514251692030948266
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 ZBTB16 TTC28 DSG2 VIRMA MADD SPICE1 RBSN MDN1 RESF1 CEP95 ARHGAP21 ABTB2 WNK3 CCSER1

2.20e-058611691536931259
Pubmed

Analysis of axonal regeneration in the central and peripheral nervous systems of the NG2-deficient mouse.

VCAN CSPG4

2.35e-052169217900358
Pubmed

Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.

SHH IHH

2.35e-052169228574612
Pubmed

Involvement of tenascin-C and PG-M/versican in flexor tenosynovial pathology of idiopathic carpal tunnel syndrome.

TNC VCAN

2.35e-052169216493581
Pubmed

Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice.

LDLR APOM

2.35e-052169218006500
Pubmed

Hedgehog can drive terminal differentiation of amniote slow skeletal muscle.

SHH IHH

2.35e-052169215238161
Pubmed

Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional.

LDLR BMP1

2.35e-052169231600776
Pubmed

Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.

LDLR AKT2

2.35e-052169224220638
Pubmed

New insight into hedgehog signaling in hematological malignancies.

SHH IHH

2.35e-052169224991722
Pubmed

Cleavage of the carboxyl tail from the G3 domain of aggrecan but not versican and identification of the amino acids involved in the degradation.

ACAN VCAN

2.35e-052169211932252
Pubmed

The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients.

SHH IHH

2.35e-052169226201092
Pubmed

Differential requirements for shh in mammary tissue and hair follicle morphogenesis.

SHH IHH

2.35e-052169212217324
Pubmed

Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells.

SHH NELL1

2.35e-052169222264144
Pubmed

Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes.

TNC ACAN

2.35e-05216927524681
Pubmed

Developmental emergence of two-stage nonlinear synaptic integration in cerebellar interneurons.

DLG4 NOS1

2.35e-052169234730085
Pubmed

[HIV-1gp120 injures neurons by alteration of neuronal expressions of NR2B and PSD-95].

GRIN2B DLG4

2.35e-052169224491052
Pubmed

Diversity of desmosomal proteins in regenerating epidermis: immunohistochemical study using a human skin organ culture model.

DSC3 DSG2

2.35e-052169210482015
Pubmed

Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis.

LDLR AKT2

2.35e-052169225392271
InteractionPCDHA10 interactions

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.79e-10221687int:PCDHA10
InteractionPCDHA8 interactions

EPHB4 PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 TMEM131L

7.18e-10551689int:PCDHA8
InteractionPCDHA7 interactions

PCDHA12 PCDHA7 PCDHA4 PCDHA2

4.37e-06141684int:PCDHA7
InteractionNXPH2 interactions

MADD FREM2 FAT1 IGF2R CELSR2

7.45e-06331685int:NXPH2
InteractionPTCH2 interactions

SHH VIRMA DHH IHH

2.03e-05201684int:PTCH2
InteractionTOP3B interactions

EPHB4 PITPNM2 EPRS1 SPEG CYB561D2 HIP1R LAMA5 MSH3 PFKL LDLR MADD CRKL LONP1 FAT1 IGF2R MDN1 PTPRF CELSR2 CSPG4 USP40 DIAPH2 ACIN1 AKT2 CIAO2A SPEN ARHGAP21 ABTB2 RAD9A

3.24e-05147016828int:TOP3B
Cytoband5q31

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 CDC23

1.15e-0811516885q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

FSTL4 PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 CDC23

1.74e-062981689chr5q31
GeneFamilyClustered protocadherins

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.52e-0764114720
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SPEG FSTL5 FSTL4 IGSF22 PXDN PTPRF HMCN1 CNTN1

8.22e-061611148593
GeneFamilyCadherin related

CDH23 FAT1 FAT2

1.56e-0417114324
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ACAN VCAN

2.35e-0441142574
GeneFamilyWD repeat domain containing

COPA NBEAL1 THOC6 PPP2R2B PPP2R2C CFAP52 DAW1 DCAF12

2.56e-042621148362
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD3 ACAN VCAN CSMD1

4.58e-045711441179
GeneFamilyCytosolic iron-sulfur assembly components

NUBP1 CIAO2A

5.81e-04611421028
GeneFamilyDesmosomal cadherins

DSC3 DSG2

8.11e-04711421188
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PKD1L2 ACAN VCAN

2.19e-034111431298
GeneFamilySorting nexins|PX-BAR domain containing

SNX4 SNX33

2.50e-031211421290
GeneFamilyPDZ domain containing

PCLO PDZD7 DLG4 NOS1 ARHGAP21

2.77e-0315211451220
GeneFamilyCD molecules|Type II classical cadherins

CDH10 CDH12

2.94e-031311421186
GeneFamilyFibronectin type III domain containing

EPHB4 TNC IGSF22 PTPRF CNTN1

3.45e-031601145555
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2B PPP2R2C

3.92e-03151142696
GeneFamilyAAA ATPases

PSMC1 LONP1 MDN1

4.55e-03531143413
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

SPEG FSTL5 RBP3 PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 HENMT1 NOS1

4.83e-0823816812M2020
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

SPEG FSTL5 RBP3 PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 HENMT1 NOS1

1.32e-0726116812MM1277
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

DOCK4 ZBTB38 SPEG PPFIA2 PCLO PEG3 LAMA5 PCDHA7 PDZD7 CSMD3 TENM2 NELL1 PPP2R2B PPP2R2C FAT2 MDN1 VCAN PCDH19 CSMD1 WNK3 CNTN1 CCSER1

2.51e-06110616822M39071
CoexpressionBLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_DN

DSC3 PCDHA4 AHCY SWI5 TPPP3 CNTN1 FAM149A

2.89e-06961687M34017
CoexpressionGSE45365_NK_CELL_VS_CD8A_DC_DN

PPFIA2 FSTL5 RBP3 CDH23 TEX55 CRKL SBNO1 IHH CNTN1

5.84e-061991689M10029
CoexpressionNABA_MATRISOME

TNC SHH LAMA5 MUC16 FLG2 FREM3 ADAM12 F13A1 BMP1 NELL1 C1QL2 FREM2 PXDN DHH HMCN1 ACAN VCAN CSPG4 IHH ITIH6

1.00e-05102616820M5889
CoexpressionNABA_MATRISOME

TNC SHH LAMA5 MUC16 FLG2 FREM3 ADAM12 F13A1 BMP1 NELL1 C1QL2 FREM2 PXDN DHH HMCN1 ACAN VCAN CSPG4 IHH

2.69e-05100816819MM17056
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

MUC16 BMP1 PXDN HMCN1

3.92e-05301684M47990
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOMTN

DOCK4 PPFIA2 FSTL5 PCDHA7 CSMD3 TENM2 NELL1 C1QL2 PPP2R2B PPP2R2C ABCC8

4.51e-0538916811M39073
CoexpressionGSE42724_NAIVE_VS_MEMORY_BCELL_DN

MAN2A1 LDLR THOC6 PRKD3 IGF2R VCAN AKT2 DHRSX

4.68e-052001688M9793
CoexpressionHALLMARK_APICAL_JUNCTION

DSC3 SPEG BMP1 PPP2R2C ICAM5 VCAN AKT2 CNTN1

4.68e-052001688M5915
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA_TUMOR_CELL_DERIVED

PXDN HMCN1 CSPG4

5.45e-05121683M47983
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

ZBTB16 POR GRIN2B PFKL BCOR TENM2 NELL1 MDN1 ACIN1 CSMD1 CNTN1

8.39e-0541716811M39224
CoexpressionAtlascerebral cortex

PCSK1 DOCK4 PPFIA2 FSTL5 PCLO FSTL4 PCDHA7 PCDHA6 PCDHA4 GRIN2B FREM3 CSMD3 TENM2 KIAA0319 NELL1 C1QL2 PPP2R2B PPP2R2C CELSR2 ICAM5 ABCC8 KCNJ9 PCDH19 DLG4 RXFP1 CSMD1 CDH10 CDH12 CNTN1

1.71e-06142816529cerebral cortex
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 LDLR C1QL2 ABCC8 VCAN CSPG4 CSMD1 NOS1 CDH10 WNK3 CNTN1

1.55e-111991681219a97e27a4758e794ce7246d295e112b47931a48
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 SPTA1 PCLO GRIN2B PKD1L2 CSMD3 FREM2 FAT1 HMCN1 CSMD1 CNTN1

1.22e-10184168112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 SPTA1 PCLO GRIN2B PKD1L2 CSMD3 FREM2 FAT1 HMCN1 CSMD1 CNTN1

1.22e-1018416811ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 SPTA1 PCLO GRIN2B PKD1L2 CSMD3 FREM2 FAT1 HMCN1 CSMD1 CNTN1

1.22e-10184168112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 TTC28 PCLO PEG3 LDLR MADD NELL1 PTPRF ABCC8 PDE5A CNTN1

1.83e-10191168113387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 TTC28 PCLO PEG3 TENM2 LDLR MADD BMP1 NELL1 ABCC8 PDE5A

2.28e-1019516811bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 LDLR C1QL2 ABCC8 VCAN CSPG4 CSMD1 NOS1 CDH10 CNTN1

2.83e-1019916811333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 LDLR C1QL2 ABCC8 VCAN CSPG4 CSMD1 NOS1 CDH10 CNTN1

2.83e-1019916811e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 LDLR C1QL2 ABCC8 VCAN CSPG4 CSMD1 NOS1 CDH10 CNTN1

2.98e-1020016811ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 PCLO PEG3 ADAM12 LDLR MADD BMP1 NELL1 ABCC8 PDE5A

3.32e-09192168105b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 COPA TTC28 PCLO PEG3 LDLR MADD BMP1 PTPRF ABCC8

3.49e-0919316810471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 COPA TTC28 PCLO PEG3 LDLR MADD BMP1 PTPRF ABCC8

3.49e-0919316810fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PCLO PEG3 TENM2 LDLR MADD PTPRF ABCC8 PDE5A

4.28e-081881689a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R PCDHA6 CSMD3 C1QL2 ACAN VCAN CSPG4 NOS1 CNTN1

4.68e-0819016896c7e1086c0a274cd5527c3104106e372811c9905
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 PCLO PEG3 ADAM12 LDLR BMP1 NELL1 ABCC8 PDE5A

4.90e-081911689f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 TTC28 PCLO PEG3 ADAM12 MADD PTPRF ABCC8 PDE5A

5.12e-0819216891304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 COPA TTC28 PEG3 LDLR MADD BMP1 PTPRF ABCC8

5.60e-0819416893a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 TTC28 PCLO PEG3 ADAM12 MADD PTPRF ABCC8 PDE5A

5.60e-08194168992b39a935e8c577eb1123d706d168fa13cf3344c
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 COPA TTC28 PEG3 LDLR MADD BMP1 PTPRF ABCC8

5.60e-0819416890b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 TTC28 PCLO ADAM12 LDLR MADD NELL1 PDE5A CNTN1

5.85e-08195168958b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO PEG3 GRIN2B CSMD3 TENM2 CSMD1 CDH12 CNTN1 CCSER1

6.67e-0819816898ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ZBTB16 PCLO SHH LAMA5 RANBP17 BMP1 PTPRF CDH10

4.91e-0718316886821dca076318115d360ff426eb1218cfe104063
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PPFIA2 PCLO MUC16 GRIN2B CSMD3 VCAN DIAPH2 CSMD1

5.55e-07186168823b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FSTL5 PCLO SHH FREM2 PTPRF CDH10 FAM149A CCSER1

6.26e-0718916887659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAN2A1 DSC3 NUP62CL PEG3 NOX3 CSPG4 RXFP1 CNTN1

6.26e-071891688d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNC SPEG ADAM12 ACAN VCAN CSPG4 TMEM131L PDE5A

6.52e-07190168870c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PEG3 LDLR MADD PTPRF ABCC8 PDE5A CNTN1

6.78e-071911688a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 PPFIA2 GRIN2B TENM2 KIAA0319 NELL1 ICAM5 KCNJ9

7.34e-071931688461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 PPFIA2 GRIN2B TENM2 KIAA0319 NELL1 ICAM5 KCNJ9

7.34e-0719316880dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK4 TTC28 TNC CSMD3 TENM2 HMCN1 VCAN CNTN1

7.63e-071941688011e14d9ed1393275f892060e7708ffadcd0767f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PCLO PEG3 LDLR MADD PTPRF ABCC8 PDE5A

7.93e-0719516883e519cffa6144a62b06124642a14c9ff39b76554
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 C1QL2 ACAN VCAN CSPG4 NOS1 CNTN1

8.24e-071961688f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1R CSMD3 C1QL2 ACAN VCAN CSPG4 NOS1 CNTN1

8.24e-071961688671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIA2 PCLO GRIN2B CSMD3 TENM2 CSMD1 CNTN1 CCSER1

8.89e-071981688c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO PEG3 GRIN2B CSMD3 TENM2 CSMD1 CNTN1 CCSER1

8.89e-0719816886d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIA2 PCLO PEG3 GRIN2B CSMD3 CSMD1 CNTN1 CCSER1

8.89e-0719816880ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-072001688f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-072001688cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-072001688c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 TNC FSTL5 PCLO FSTL4 RXFP1 CDH10 CCSER1

9.59e-0720016881a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-0720016884fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 TNC FSTL5 PCLO FSTL4 RXFP1 CDH10 CCSER1

9.59e-0720016886f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 TNC FSTL5 PCLO FSTL4 RXFP1 CDH10 CCSER1

9.59e-07200168886705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 TNC FSTL5 PCLO FSTL4 RXFP1 CDH10 CCSER1

9.59e-072001688db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-072001688310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIN2B CSMD3 NELL1 PXDN VCAN CSPG4 CSMD1 CCSER1

9.59e-072001688961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHA2 FLG2 ADAM12 PTPRF DAW1 PCDH19 CSMD1

1.22e-0614316876df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZBTB16 FSTL4 LAMA5 CSMD3 ADAM12 PDE5A RXFP1

2.69e-0616116873b5d7a3dab479c6959a428f3954dedd989900276
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 GRIN2B CSMD3 FREM2 PPP2R2B TPPP3 CDH12

2.80e-061621687bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

DSG2 TNC PPFIA2 ADAM12 ACAN VCAN PYCR1

3.04e-0616416879b4a6007abae992db871d9f6f731d5af724de30d
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PEG3 PCDHA6 MADD ABCC8 PDE5A IP6K2

3.29e-06166168766026988509e39e41274fa0de738383219e8ff30
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PCSK1 HIP1R PPP2R2B PPP2R2C ABCC8 CDH10 WNK3

3.70e-06169168796a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TNC PELI3 PEG3 FSTL4 ACAN PCDH19 CSPG4

4.00e-061711687d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DSC3 TNC TENM2 CELSR2 HMCN1 KCNJ9 CSMD1

4.00e-061711687121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 FSTL4 F13A1 KIAA0319 CCDC68 RXFP1 CDH10

5.02e-0617716877e799333307448c6a94d1f33dbc59c543336f45e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHH C1QL2 ACAN VCAN CSPG4 CSMD1 CNTN1

5.61e-061801687fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHH C1QL2 ACAN VCAN CSPG4 CSMD1 CNTN1

5.61e-061801687907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSC3 DSG2 FSTL4 CDH23 FAT2 PTPRF CCSER1

6.03e-061821687678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSC3 DSG2 FSTL4 CDH23 FAT2 PTPRF CCSER1

6.03e-0618216878d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL5 PCLO FSTL4 KIAA0319 NELL1 RXFP1 CDH10

6.25e-061831687274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNC NUP62CL FAT1 PCDH19 CSPG4 PDE5A IHH

6.47e-06184168755dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNC NUP62CL FAT1 PCDH19 CSPG4 PDE5A IHH

6.47e-0618416877128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNC NUP62CL FAT1 PCDH19 CSPG4 PDE5A IHH

6.47e-061841687d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 FSTL4 GRIN2B MEI1 MADD ICAM5 CSMD1

6.95e-0618616877278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL5 ADAM12 C1QL2 VCAN CSPG4 CSMD1 CNTN1

7.45e-061881687a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL5 ADAM12 C1QL2 VCAN CSPG4 CSMD1 CNTN1

7.45e-061881687c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ACAN ABCC8 CSPG4 TMEM131L PDE5A CSMD1

7.71e-0618916877fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ACAN ABCC8 CSPG4 TMEM131L PDE5A CSMD1

7.71e-06189168706b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PEG3 LDLR MADD ABCC8 PDE5A CNTN1

7.71e-061891687010fdd70e9d0e21b856306a29ff877776a480319
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

DOCK4 PITPNM2 ZBTB16 FAT1 ABCC8 CCDC68 RXFP1

7.98e-0619016877f3f419fffe02934b6f27b697f7a6401072491ed
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

DSC3 DSG2 PCLO MUC16 NELL1 PTPRF DAW1

7.98e-061901687d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

SPEG PPFIA2 FAT1 PXDN HMCN1 ACAN CSMD1

8.26e-061911687fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HIP1R SHH NELL1 FREM2 PTPRF TPPP3 IHH

8.55e-061921687b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO FSTL4 GRIN2B MADD CELSR2 ICAM5 CSMD1

8.84e-061931687be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

EPRS1 MAN2A1 NBEAL1 MSH3 BCOR IGF2R SMCR8

8.84e-061931687abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO FSTL4 GRIN2B MADD CELSR2 ICAM5 CSMD1

8.84e-0619316870c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO FSTL4 GRIN2B MADD CELSR2 ICAM5 CSMD1

8.84e-0619316878689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HIP1R SHH NELL1 FREM2 PTPRF TPPP3 IHH

8.84e-0619316874b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FSTL5 SHH FREM2 PTPRF CDH10 FAM149A CCSER1

9.14e-061941687f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 FLG2 HMCN1 ABCC8 CSMD1 ITIH6 NOS1

9.46e-061951687d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 FLG2 HMCN1 ABCC8 CSMD1 ITIH6 NOS1

9.46e-06195168719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 GRIN2B TENM2 KIAA0319 NELL1 ICAM5 DLG4

9.46e-061951687ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 FSTL4 CSMD3 TENM2 PPP2R2C CSMD1 CDH12

9.46e-0619516872e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PCLO PEG3 LDLR MADD PTPRF ABCC8

9.46e-0619516877796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 KANSL1L ZBTB16 TTC28 RANBP17 DIAPH2 CCSER1

9.78e-061961687ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 COPA PEG3 POR BMP1 IGF2R AKT2

9.78e-06196168766d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO GRIN2B CSMD3 TENM2 CSMD1 CNTN1 CCSER1

9.78e-061961687676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 COPA PEG3 POR BMP1 IGF2R AKT2

9.78e-0619616879bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

DSG2 TNC NELL1 C1QL2 FAT1 PTPRF HMCN1

1.01e-0519716875e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TNC ADAM12 BMP1 HMCN1 VCAN CCDC68 PYCR1

1.04e-051981687c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCLO PEG3 GRIN2B CSMD3 CSMD1 CNTN1 CCSER1

1.04e-0519816874ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TNC ADAM12 BMP1 HMCN1 VCAN CCDC68 PYCR1

1.04e-0519816873e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 KANSL1L ZBTB16 TTC28 RANBP17 DIAPH2 CCSER1

1.04e-0519816871996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

TNC PPFIA2 ADAM12 BMP1 HMCN1 VCAN CCDC68

1.04e-051981687196257c4420ac801ed9fbb444f11718adb7560ae
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L MAN2A1 BMP1 FAT1 PXDN CEP95 VCAN

1.08e-051991687174f6013af6eafa577f84205a62927f2b367fda3
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

PCLO GRIN2B CSMD3 TENM2 CSMD1 CNTN1 CCSER1

1.11e-05200168748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

NBEAL1 TENM2 FAT1 ACAN CSPG4 PDE5A CSMD1

1.11e-0520016878c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

ZBTB38 NBEAL1 PPFIA2 FAT1 CSPG4 PDE5A CNTN1

1.11e-05200168769edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellBiopsy_Other_PF-Epithelial-Basal|Biopsy_Other_PF / Sample group, Lineage and Cell type

DSC3 DSG2 TNC FSTL4 FAT1 FAT2 CELSR2

1.11e-0520016877098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Cbln4_(Neuron.Slc17a7.Cbln4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

DSC3 MEI1 FAT2 CFAP52 IHH

1.23e-05791685d24301b6694f64e8bb1b5f0673f653d25d45d3eb
ComputationalGenes in the cancer module 70.

DSG2 PFKL BMP1 CSPG4 RAD9A

3.77e-0543965MODULE_70
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

MAN2A1 DSG2 LDLR BMP1 FAT1 IGF2R PXDN PTPRF CELSR2

2.23e-0615516796817_DN
Disease1,5 anhydroglucitol measurement

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 PKD1L2

3.29e-12291668EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

6.29e-07871667EFO_0004340, EFO_0004765
Diseaseneuroticism measurement, cognitive function measurement

NBEAL1 PCLO PCDHA13 PCDHA12 NOX3 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 NELL1 PPP2R2B CSMD1 NOS1 CDH12

8.15e-0756616615EFO_0007660, EFO_0008354
Diseasealcohol dependence, risky sexual behaviour measurement

FSTL5 IGSF22 CCSER1

9.59e-0681663EFO_0007877, MONDO_0007079
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

SHH DHH IHH

1.43e-0591663DOID:0050338 (implicated_via_orthology)
Diseaseunipolar depression

TNC PCLO PCDHA6 PCDHA4 PCDHA3 PCDHA2 GRIN2B MEI1 CSMD3 TENM2 LDLR NELL1 FAT1 KCNJ9 VCAN CCDC68 CSMD1 NOS1 CNTN1 CCSER1

1.58e-05120616620EFO_0003761
Diseasepost-traumatic stress disorder

DOCK4 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 CSMD1 NOS1

2.01e-052021668EFO_0001358
Diseaseneutrophil count, basophil count

ZBTB16 PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.20e-052241668EFO_0004833, EFO_0005090
Diseasecreatinine measurement

ZBTB16 USP11 SPEG PPFIA2 SHH LAMA5 POR LDLR F13A1 NELL1 IGF2R CELSR2 CSPG4 TMEM131L AKT2 DLEC1 DCAF12

4.94e-0599516617EFO_0004518
Diseaseage-related hearing impairment

TTC28 CDH23 SNX33 CSMD3 ACAN CCDC68 DLG4 DLEC1 CSMD1

9.73e-053241669EFO_0005782
Diseasepost-traumatic stress disorder symptom measurement

PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.02e-04821665EFO_0008535
DiseaseTourette syndrome

PITPNM2 MUC16 CSMD3 TENM2

1.82e-04501664EFO_0004895
DiseaseDisorder of eye

RBP3 CDH23 PDZD7 IDH3B BCOR FREM2 VCAN

2.07e-042121667C0015397
Diseaseurate measurement, bone density

SPTLC3 PLB1 TTC28 PPFIA2 FSTL5 LAMA5 TENM2 RANBP17 NELL1 USP40 DHX35 CDH12

2.12e-0461916612EFO_0003923, EFO_0004531
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

FSTL5 CSMD3 TENM2 NELL1 HMCN1 PDE5A CSMD1

2.32e-042161667EFO_0007925, EFO_0007927
Diseaseperipheral arterial disease

CSMD3 LDLR CELSR2 CCSER1

2.45e-04541664EFO_0004265
Diseaseneurotic disorder

PCLO CCDC68 CSMD1 NOS1 CCSER1

2.72e-041011665EFO_0004257
DiseaseAbnormality of refraction

ZBTB38 PCLO PCDHA13 PCDHA12 PCDHA7 PCDHA6 PCDHA4 PCDHA3 PCDHA2 GRIN2B PTPRF DLEC1

4.50e-0467316612HP_0000539
Diseaseparental longevity

PCLO POR GRIN2B PKD1L2 LDLR NELL1 IGF2R CELSR2 ABCC8 CSMD1

5.14e-0449416610EFO_0007796
Diseaseschizophrenia (implicated_via_orthology)

CSMD3 SBNO1 CSMD1 NOS1

5.94e-04681664DOID:5419 (implicated_via_orthology)
DiseaseLDL cholesterol change measurement

LDLR CELSR2

6.49e-0471662EFO_0007804
Diseasecatalase measurement

CELSR2 ABTB2

6.49e-0471662EFO_0008071
Diseaseautism spectrum disorder (is_marker_for)

SHH IHH

6.49e-0471662DOID:0060041 (is_marker_for)
DiseaseColorectal Carcinoma

FSTL5 PEG3 AMDHD2 RBP3 CSMD3 TXNRD1 NELL1 FAT1 ICAM5 ABCC8 ACIN1 CNTN1

6.53e-0470216612C0009402
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

SHH DLG4 NOS1

7.00e-04311663DOID:3328 (biomarker_via_orthology)
Diseaserespiratory symptom measurement, COVID-19

GRIN2B FREM2 FAT1 CSMD1

8.18e-04741664EFO_0007939, MONDO_0100096
DiseaseNRF2 measurement

GRIN2B NELL1

8.61e-0481662EFO_0009794
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

PCLO TENM2 PPP2R2B PTPRF CCDC68 CSMD1

9.72e-042001666EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseaseendometrial cancer (is_implicated_in)

MSH3 AKT2 ATM

1.09e-03361663DOID:1380 (is_implicated_in)
Diseasecerebrospinal fluid biomarker measurement, t-tau measurement

TTC28 AKT2

1.10e-0391662EFO_0004760, EFO_0006794
Diseasecystic kidney disease (implicated_via_orthology)

EPHB4 LAMA5

1.37e-03101662DOID:2975 (implicated_via_orthology)
Diseaseresting heart rate

SPEG PPFIA2 CSMD1 ARHGAP21 CDC23

1.58e-031491665EFO_0004351
DiseaseBipolar Disorder

FSTL5 PCLO HIP1R GRIN2B PFKL PPP2R2C DLG4 AKT2 CSMD1

1.59e-034771669C0005586
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2B AHCY

1.67e-03111662DOID:9279 (implicated_via_orthology)
Diseaseinterleukin-6 measurement, response to stimulus

FSTL5 MUC16

1.67e-03111662EFO_0004810, GO_0050896
Diseaseglycerophosphorylcholine measurement

GRIN2B CCSER1

1.67e-03111662EFO_0020018
Diseasetriglycerides in large LDL measurement

LDLR IGF2R CELSR2

1.83e-03431663EFO_0022319
Diseasecholesteryl ester measurement, intermediate density lipoprotein measurement

LDLR IGF2R CELSR2 DLG4

1.99e-03941664EFO_0008595, EFO_0010351
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2B PPP2R2C

2.00e-03121662DOID:1441 (implicated_via_orthology)
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CDH23 CELSR2

2.00e-03121662EFO_0801493
Diseasehyperinsulinism (is_implicated_in)

PTPRF ABCC8

2.00e-03121662DOID:2018 (is_implicated_in)
Diseasegranulins measurement

CDH23 CELSR2

2.00e-03121662EFO_0008141
DiseaseGastric Adenocarcinoma

EPHB4 SPEG ATM

2.09e-03451663C0278701
Diseaseopioid dependence

GRIN2B CSMD3 F13A1 NELL1 DLEC1 CSMD1

2.30e-032371666EFO_0005611
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 PDZD7

2.36e-03131662C1846647
DiseaseFetal Alcohol Spectrum Disorders

SRF NOS1

2.36e-03131662C2985290
Diseasecolon carcinoma (is_marker_for)

CRKL IGF2R

2.36e-03131662DOID:1520 (is_marker_for)
DiseaseSalivary Gland Neoplasms

FAT1 VCAN SPEN

2.36e-03471663C0036095
DiseaseAdenoid Cystic Carcinoma

BCOR FAT1 VCAN ATM

2.49e-031001664C0010606
Diseasephospholipids in medium LDL measurement

LDLR IGF2R CELSR2

2.66e-03491663EFO_0022183
Diseasecholesterol in medium LDL measurement

LDLR IGF2R CELSR2

2.66e-03491663EFO_0022224
Diseasecholesterol in small LDL measurement

LDLR IGF2R CELSR2

2.66e-03491663EFO_0022227
DiseasePneumoconiosis

CDH23 ACAN

2.74e-03141662C0032273
DiseaseBagassosis

CDH23 ACAN

2.74e-03141662C0004681
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

LDLR CELSR2

2.74e-03141662EFO_0004611, EFO_0008589
Diseasedepressive symptom measurement

PCLO PCDHA6 PCDHA4 PCDHA3 PCDHA2 TENM2 CCDC68 NOS1

2.94e-034261668EFO_0007006
Diseasefree cholesterol to total lipids in small HDL percentage

LDLR MADD CELSR2

2.99e-03511663EFO_0022285
Diseaseattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder

PCLO PTPRF CCDC68

2.99e-03511663EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
Diseaseinfant head circumference

ZBTB38 SBNO1

3.15e-03151662EFO_0004577
Diseaseimpotence (implicated_via_orthology)

PDE5A NOS1

3.15e-03151662DOID:1875 (implicated_via_orthology)
Diseaseresponse to statin, LDL cholesterol change measurement

LDLR CELSR2

3.15e-03151662EFO_0007804, GO_0036273
Diseasehepcidin:transferrin saturation ratio

MUC16 NELL1

3.15e-03151662EFO_0007902
Diseasephospholipids in medium VLDL measurement

LDLR IGF2R CELSR2

3.16e-03521663EFO_0022154
Diseasetotal lipids in medium LDL

LDLR IGF2R CELSR2

3.16e-03521663EFO_0022180
Diseasetotal lipids in LDL measurement

LDLR IGF2R CELSR2

3.16e-03521663EFO_0022308
Diseasemonoclonal gammopathy

TNC HFM1 CSMD1

3.33e-03531663EFO_0000203
Diseasecholesterol in small VLDL measurement

LDLR IGF2R CELSR2

3.33e-03531663EFO_0022228
Diseasetotal lipids in medium VLDL

LDLR IGF2R CELSR2

3.51e-03541663EFO_0022153
DiseaseUnipolar Depression

ZBTB16 PCLO FREM3 NELL1 DLG4 NOS1

3.56e-032591666C0041696
Diseasevision disorder

PXDN CNTN1

3.58e-03161662MONDO_0021084
Diseaseresponse to triptolide, cytotoxicity measurement

SHH CSMD1

3.58e-03161662EFO_0006952, EFO_0007662
Diseaselipoprotein A measurement

LDLR IGF2R CELSR2 IP6K2

3.75e-031121664EFO_0006925
Diseasefree cholesterol measurement

LDLR IGF2R CELSR2 DLG4

3.87e-031131664EFO_0008591
Diseasetriglycerides in LDL measurement

LDLR IGF2R CELSR2

3.90e-03561663EFO_0022320
Diseasesevere acute respiratory syndrome, COVID-19

SNX4 PCDHA6 TENM2 PXDN DIAPH2 DHRSX CSMD1 ABTB2

3.93e-034471668EFO_0000694, MONDO_0100096
Diseasepre-malignant neoplasm (biomarker_via_orthology)

SHH ATM

4.05e-03171662DOID:0060071 (biomarker_via_orthology)
Diseaseischemia (implicated_via_orthology)

LONP1 AKT2

4.05e-03171662DOID:326 (implicated_via_orthology)
DiseaseFetal Alcohol Syndrome

SRF NOS1

4.05e-03171662C0015923
Diseasetotal lipids in large LDL

LDLR IGF2R CELSR2

4.10e-03571663EFO_0022163
Diseasecholesterol in large LDL measurement

LDLR IGF2R CELSR2

4.10e-03571663EFO_0021901
Diseasecortical thickness

PITPNM2 ZBTB16 NBEAL1 POLR1C SHH MSH3 ADAM12 TENM2 NELL1 PTPRF VCAN DLEC1 ARHGAP21 IP6K2

4.24e-03111316614EFO_0004840
Diseaseneuroblastoma

KANSL1L LAMA5 TENM2 CSMD1

4.24e-031161664EFO_0000621
Diseasetriglycerides in IDL measurement

LDLR IGF2R CELSR2

4.30e-03581663EFO_0022149
Diseasephospholipids in VLDL measurement

LDLR IGF2R CELSR2

4.51e-03591663EFO_0022301
Diseasephospholipids in small LDL measurement

LDLR IGF2R CELSR2

4.51e-03591663EFO_0022297
Diseaselymphocyte percentage of leukocytes

ZBTB38 TTC28 SPTA1 CDH23 PCDHA6 SIRPB1 PRKD3 TRMU SBNO1 ICAM5

4.55e-0366516610EFO_0007993
Diseasetotal lipids in VLDL measurement

LDLR IGF2R CELSR2

4.73e-03601663EFO_0022314
Diseasefree cholesterol in VLDL measurement

LDLR IGF2R CELSR2

4.96e-03611663EFO_0022276
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PCLO CDH23

5.05e-03191662EFO_0007044, EFO_0020106
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

MSH3 ATM

5.05e-03191662C1333991
Diseasesodium-coupled monocarboxylate transporter 1 measurement

LDLR CELSR2

5.05e-03191662EFO_0802076
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

MSH3 ATM

5.05e-03191662C2936783
Diseasetriglycerides in medium LDL measurement

LDLR IGF2R CELSR2

5.19e-03621663EFO_0022322
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

NBEAL1 LDLR CELSR2

5.42e-03631663EFO_0001645, EFO_0004792
Diseasetaurocholate measurement

ADAM12 NELL1

5.59e-03201662EFO_0010538
Diseasecoagulation factor measurement

F13A1 CNTN1

5.59e-03201662EFO_0004634
Diseasetemporal lobe epilepsy (is_marker_for)

SHH GRIN2B

5.59e-03201662DOID:3328 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YSTVEEAVATRTALH

ACIN1

1056

Q9UKV3
GAEIVSALEYLHSRD

AKT2

256

P31751
GEVAHVSAEITYTSK

ACOT7L

41

Q6ZUV0
RDHSYATEADIISTV

PPP2R2B

16

Q00005
RDHSYVTEADIISTV

PPP2R2C

16

Q9Y2T4
IYHLTEGSTDLRTEG

APOM

101

O95445
GEIVEHLEESTAFRY

CDC23

501

Q9UJX2
LERGHTEIDTAFLYS

AKR7L

36

Q8NHP1
LERGHTEIDTAFVYS

AKR7A3

36

O95154
SIGFLIHYESVTLES

CSMD1

856

Q96PZ7
FSTETIHDYLEVRSG

CSMD3

2156

Q7Z407
IHDYLEVRSGSSETS

CSMD3

2161

Q7Z407
DTVSLTVDGVVFHYR

VCAN

141

P13611
LRGRLVYQHDDSETT

CSPG4

966

Q6UVK1
RYVHDGSETLTDSFV

CSPG4

1431

Q6UVK1
RHEGIETVSYATQSL

ALKBH8

31

Q96BT7
TGIQHLTSDSDSEVY

ACBD5

296

Q5T8D3
STSSGLETELHYERE

ANKRD62

711

A6NC57
ETHYLQDGTDVSLAR

ADAM12

96

O43184
EVIKHSRGTYETLTS

CCSER1

801

Q9C0I3
TVSAVDRDAHSVITY

CELSR2

631

Q9HCU4
DRDAHSVITYQITSG

CELSR2

636

Q9HCU4
ALYESTSAHIIEETE

CCDC68

21

Q9H2F9
LSSQEYVHELRSGIS

DIAPH2

161

O60879
DYLEVRDGHSESSTL

BMP1

491

P13497
REELGRISDFHETYT

BCOR

856

Q6W2J9
EISHGRYTLIVTATD

CDH23

1701

Q9H251
IYISEGTHSTEEDIN

CIAO2A

116

Q9H5X1
IYETAAREHESRGVT

ATG2B

2011

Q96BY7
GHIVVYSSTEEKTTL

NBEAL1

2551

Q6ZS30
TVVGGRLTYTSTDEH

RANBP17

501

Q9H2T7
GETTYSLEHASDLRV

RBSN

306

Q9H1K0
VILRSYHEEEADSTA

RAD9A

176

Q99638
DETIIIFHSLLTGSY

EYA3

311

Q99504
ETETTIGYGHRVITD

KCNJ9

116

Q92806
ERALSSYVSVHAESG

PCDHA2

501

Q9Y5H9
ERALSSYISVHAESG

PCDHA6

501

Q9UN73
VVVREGATVYATGTH

PYCR1

126

P32322
TSDEHLSVVRYLATA

NUBP1

176

P53384
DTGEIYTTSVTLDRE

DSG2

216

Q14126
TLDREEHSSYTLTVE

DSG2

226

Q14126
EHSSYTLTVEARDGN

DSG2

231

Q14126
GESSKSSYELIVVAH

PCDH19

631

Q8TAB3
ERALSSYVSVHAESG

PCDHA7

501

Q9UN72
TGAIHTVLSLDYEET

FAT1

1826

Q14517
EIDLIRAEHSGTVLY

FAT1

2721

Q14517
FSDDVYHLTSREITI

MUC16

1106

Q8WXI7
TSTHDGIAIAYATLE

MSH3

981

P20585
ESTVHERHETTYGQT

FLG2

1381

Q5D862
ERALSSYVSVHAESG

PCDHA3

501

Q9Y5H8
SESYLLREHVSELDS

KANSL1L

616

A0AUZ9
ILYSEQEESTVHVGR

LRRC34

246

Q8IZ02
TGRDLEDEVVVSYSH

MDN1

3276

Q9NU22
SYVAAVHSSEEDLRT

MADD

1626

Q8WXG6
TGEESSIRQYELVVH

POR

236

P16435
TISETAYEISFRAHI

MAN2A1

696

Q16706
SGLDEEQHSVRTYEV

EPHB4

46

P54760
HTTCRLYGEDTVVHE

IP6K2

386

Q9UHH9
LTARSSLEEEVYHVD

FAM149A

391

A5PLN7
DAIATGHYARTSLED

TRMU

121

O75648
QRDILEGSVVYTHTS

FREM2

1006

Q5SZK8
LVGTEESHIYRVSFT

CFAP52

306

Q8N1V2
LEIGYSSHLRADSTV

PCLO

3596

Q9Y6V0
YSLAEEETLGRHFSV

FAT2

3566

Q9NYQ8
HGTDSRTVTVGVEYR

ICAM5

731

Q9UMF0
TSSEDGVRRIVHLYT

PDZD7

201

Q9H5P4
GVRRIVHLYTTSDDF

PDZD7

206

Q9H5P4
YVSGELEHVTRRTLS

PFKL

761

P17858
LSYHASAAEEETREL

PDE5A

526

O76074
EVYTLRGHSAEIISL

DAW1

211

Q8N136
TRIGERYITHESDDA

PRKD3

846

O94806
SSDSLRHVYGELDVQ

F13A1

711

P00488
SDVVESLDEIYHTGT

LONP1

176

P36776
TLRYELHSETQRGDV

LAMA5

1711

O15230
DRGTGHVSSTYVEEL

PPP4R3B

21

Q5MIZ7
VVRGDHTFADSYITV

PITPNM2

1086

Q9BZ72
GDYVLSVSENSRVSH

CRKL

46

P46109
EGREYSRSVIHSLVA

PEG3

826

Q9GZU2
IRELEHSYFELESSG

NELL1

106

Q92832
ETHLEIESSSLLYSG

ACAN

2231

P16112
LLYSGEETHTVETAT

ACAN

2241

P16112
TRHAYGEDTYVISTV

PKD1L2

756

Q7Z442
SEVHISNVRYEDTGA

FSTL5

396

Q8N475
YITVRSDGSLHIERV

HMCN1

936

Q96RW7
RYRSSSVLSHEEVGD

MEI1

1181

Q5TIA1
HEDIFGVTLRTYEVT

NOS1

1396

P29475
ERALSSYVSVHAESG

PCDHA13

501

Q9Y5I0
RTASDSHYVTLIIGD

HFM1

1021

A2PYH4
ERALSSYVSVHAESG

PCDHA4

501

Q9UN74
ELESIGELFSRSVTH

ATM

2181

Q13315
DAVSTLEEGHAQYLT

HIP1R

666

O75146
LTITLYHGSVVERDS

HENMT1

106

Q5T8I9
QTEGEYSSLEHESAR

IDH3B

166

O43837
HADAIYTVSLLVTEG

IGSF22

146

Q8N9C0
IRREYSSVFSHGVSI

DOCK4

371

Q8N1I0
TGVITTVSHYLDREV

DSC3

301

Q14574
SNSVVLHLDSGDEVY

C1QL2

246

Q7Z5L3
RSSYLFEVHEDIEVG

CDH10

386

Q9Y6N8
SGIRSVSFYEHIITV

DCAF12

341

Q5T6F0
HYEGRALDITTSDRD

DHH

141

O43323
YAVTTGDHGIIRTLD

COPA

551

P53621
DEAHERTLYTDIAIG

DHX35

176

Q9H5Z1
SELHISSVRYEDTGA

FSTL4

396

Q6MZW2
DHVVALSNESTVTGY

CNTN1

926

Q12860
VVERDHTYSQASTGL

FOXRED1

96

Q96CU9
EEEYRSALHTIAGAL

C1orf112

801

Q9NSG2
ARVVTVSSATHYVAE

DHRSX

176

Q8N5I4
GLLEYLTERISETSH

CEP95

106

Q96GE4
SHLYGTSVQSVREVA

DLG4

606

P78352
DYHGFTVSTVEEERT

ETHE1

196

O95571
TDYFVIVSGTSTRHL

MALSU1

121

Q96EH3
IEVTVSERTGISYVH

ITIH6

176

Q6UXX5
VFTIDETTGDIHAIR

CDH12

101

P55289
SLTHYILDTRIEGEE

CCDC168

4276

Q8NDH2
GHSSYSVDDVIVLEI

DLEC1

731

Q9Y238
RGISEETTTGVHNLY

AHCY

151

P23526
TSGHVELYTISVERG

SBNO1

1171

A3KN83
ETESHIYRALRTASG

CYB561D2

6

O14569
EESLHYEGRAVDITT

IHH

141

Q14623
RTHLDTSAELRYSVG

PPFIA2

546

O75334
AYDHSRVILTSIDGV

PTPRF

1386

P10586
SYSLVERRVGEHALS

PCDHA12

491

Q9UN75
ERRVGEHALSSYVSV

PCDHA12

496

Q9UN75
SLTVTDGTHTDFYVL

FREM3

1621

P0C091
AYRGLETGSREVVSH

HPD

46

P32754
RTYHSVGDSVLRSAT

IGF2R

91

P11717
TAYLIETRSVEHTDG

SNX4

81

O95219
SIEGVTHALRTTEYH

EPRS1

386

P07814
HSDSEVASLAREVYT

TCEANC2

91

Q96MN5
TSEQTDLRLYGLVDH

TEX55

286

Q96M34
EESLHYEGRAVDITT

SHH

136

Q15465
SYHVSGIGTRRISTE

TMEM131L

181

A2VDJ0
GTVVASHTSVERITY

RESF1

81

Q9HCM1
TLSRSHSVIVEYTHD

PELI3

131

Q8N2H9
VESRRVVSEDTSHYI

ERCC5

276

P28715
TSRTLTYIREHSVVD

PRELID3A

71

Q96N28
VEIVRSGISTNHADY

SNX33

56

Q8WV41
GSSECYVVVTIDEHT

SHOC1

906

Q5VXU9
VYGLDDSEHISSIVD

SGO2

216

Q562F6
AISHTGVLYITETDE

TENM2

1481

Q9NT68
DVLEVYGTGVASTRH

SPTLC3

186

Q9NUV7
RVRDHYIFSVESTGV

POLR1C

301

O15160
DLSEVAEVSRQYHGT

PLB1

216

Q6P1J6
AIVSTSVGSEHYVSI

PSMC1

121

P62191
SVGSEHYVSILSFVD

PSMC1

126

P62191
EEESFHYTRVILGST

NOX3

36

Q9HBY0
STETLDSSYVVGHVL

SPICE1

271

Q8N0Z3
LVASETGHVYTFATR

SRF

186

P11831
DLDYTRTVLHTETEI

SMCR8

201

Q8TEV9
ITYAEHRRSLTVDSG

ABTB2

431

Q8N961
SHFAETVEGLTTIRA

ABCC8

1201

Q09428
GDSVSYSIHSTARVV

SIRPB1

201

O00241
YSIHSTARVVLTRGD

SIRPB1

206

O00241
AYIDGHSVVIFSRST

TXNRD1

61

Q16881
VSEGYSVDELEDHIT

SWI5

181

Q1ZZU3
TTEDYDHEITGLRVS

ZG16B

66

Q96DA0
SSVITSARELHYGRE

ZBTB16

286

Q05516
GVYLLTSHRTATAAE

RBP3

536

P10745
TSVQIHGTSEERYGL

SPEN

366

Q96T58
LLLTSVHEDDSGVYT

SPEG

1026

Q15772
YGSTEHEARSIRDLA

PXDN

916

Q92626
TVEYNISGAERTAHI

TNC

1481

P24821
ETGTFTRVLRGHTDY

THOC6

156

Q86W42
LHSEDTESIGAQIYS

RXFP1

566

Q9HBX9
GHYASDNVTTRLSEV

SPTA1

651

P02549
AVDRLTDTSRYTGSH

TPPP3

121

Q9BW30
IASVREALGVESHYS

TTC28

1296

Q96AY4
VLSDHTRNSAEGTEY

WASHC4

976

Q2M389
SSFGRLSYIHVTVDT

ERVK-19

661

Q9WJR5
RTLAEHSYAVSSVAE

ZBTB38

216

Q8NAP3
REVVYLESSTTAVHA

TMEM177

156

Q53S58
HRTEEVRYGVSEQTS

ARHGAP21

296

Q5T5U3
ETSLVGTSGHDLIYR

USP40

146

Q9NVE5
TLAIYGSVDRVISHD

VIRMA

121

Q69YN4
NSEGSLDRLYDTHIT

USP11

246

P51784
HFATERATGVDSITV

WNK3

821

Q9BYP7
LVEGVYTFHLRVTDS

KIAA0319

781

Q5VV43
LDRAHGVSSYDTVIS

LDLR

456

P01130
DDSLHVQATYISGEL

AMDHD2

386

Q9Y303
LTYLEESTRDQSGLH

NUP62CL

151

Q9H1M0
SDRYSGHDDLIRSDV

GRIN2B

1046

Q13224
IRSDVSDISTHTVTY

GRIN2B

1056

Q13224
ATIEYSRRGDLHVTL

PCSK1

511

P29120