Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEE POTEF POTEI	1.52e-05	11	92	3	GO:0098973
GeneOntologyMolecularFunction	melanocyte-stimulating hormone receptor activity	MC1R MC4R	6.28e-05	3	92	2	GO:0004980
GeneOntologyMolecularFunction	acetate-CoA ligase activity	DIP2A ACSS2	1.25e-04	4	92	2	GO:0003987
GeneOntologyMolecularFunction	G protein-coupled receptor activity	TAS2R4 ADRA1D HTR1A ADRA2B MAS1L GPR32P1 OR5AU1 MC1R ADGRB1 MC4R OR14I1 ADGRF3 TAS2R38	2.01e-04	884	92	13	GO:0004930
GeneOntologyMolecularFunction	NAADP-sensitive calcium-release channel activity	MCOLN1 MCOLN2	2.08e-04	5	92	2	GO:0072345
GeneOntologyMolecularFunction	alpha-adrenergic receptor activity	ADRA1D ADRA2B	3.11e-04	6	92	2	GO:0004936
GeneOntologyMolecularFunction	melanocortin receptor activity	MC1R MC4R	3.11e-04	6	92	2	GO:0004977
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEE POTEF POTEI	4.26e-04	32	92	3	GO:0099186
GeneOntologyMolecularFunction	acyltransferase activity	TRIM49 NAT8L RNF123 TRIM49C TRIM49D1 RNF225 PORCN HERC1 ZDHHC17 TRIM49B TRIM48	8.61e-04	775	92	11	GO:0016746
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	ADRA1D HTR1A ADRA2B	8.89e-04	41	92	3	GO:0008227
GeneOntologyMolecularFunction	adrenergic receptor activity	ADRA1D ADRA2B	9.22e-04	10	92	2	GO:0004935
GeneOntologyMolecularFunction	structural constituent of synapse	POTEE POTEF POTEI	9.54e-04	42	92	3	GO:0098918
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2B ATM	1.12e-03	11	92	2	GO:0016303
GeneOntologyMolecularFunction	iron ion transmembrane transporter activity	MCOLN1 MCOLN2	1.12e-03	11	92	2	GO:0005381
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	TAS2R4 FLT1 ADRA1D HTR1A ADRA2B MAS1L GPR32P1 OR5AU1 ABCC8 MC1R ADGRB1 MC4R OR14I1 ADGRF3 TAS2R38	1.26e-03	1353	92	15	GO:0004888
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 HERC1 TRIM49B TRIM48	1.53e-03	473	92	8	GO:0004842
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC7A2 SLC7A7	1.58e-03	13	92	2	GO:0061459
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 TRIM49B TRIM48	1.66e-03	372	92	7	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 TRIM49B TRIM48	2.43e-03	398	92	7	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 HERC1 TRIM49B TRIM48	2.50e-03	512	92	8	GO:0019787
GeneOntologyMolecularFunction	zinc ion binding	TRIM49 PDE2A TIMP2 ABCC8 TRIM49C TRIM49D1 KDM2B ERVK-7 TRIM49B AGBL1 TRIM48	2.61e-03	891	92	11	GO:0008270
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	MCOLN1 MCOLN2	3.06e-03	18	92	2	GO:0015278
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 HERC1 TRIM49B TRIM48	3.16e-03	532	92	8	GO:0016755
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	MAS1L GPR32P1 MC1R MC4R	3.34e-03	133	92	4	GO:0008528
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEE POTEF ADGRB1 POTEI	1.11e-05	31	93	4	GO:0098974
GeneOntologyBiologicalProcess	postsynapse organization	POTEE DIP2A DLG5 CDK5R1 HTR1A POTEF ADGRB1 DOCK7 POTEI	1.20e-05	313	93	9	GO:0099173
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEE POTEF ADGRB1 POTEI	1.82e-05	35	93	4	GO:0099188
GeneOntologyBiologicalProcess	adenylate cyclase-activating G protein-coupled receptor signaling pathway	PDE2A ADRA1D ADRA2B MC1R ADGRB1 MC4R ADGRF3	2.53e-05	191	93	7	GO:0007189
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	PDE2A ADRA1D HTR1A ADRA2B MC1R ADGRB1 MC4R ADGRF3	4.55e-05	286	93	8	GO:0007188
GeneOntologyBiologicalProcess	acetate metabolic process	NAT8L ACSS2	1.20e-04	4	93	2	GO:0006083
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEE POTEF POTEI	4.10e-04	32	95	3	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEE POTEF POTEI	4.10e-04	32	95	3	GO:0043189
Domain	SPRY	TRIM49 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B TRIM48	3.47e-07	94	90	7	PF00622
Domain	SPRY_dom	TRIM49 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B TRIM48	3.47e-07	94	90	7	IPR003877
Domain	B30.2/SPRY	TRIM49 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B TRIM48	3.73e-07	95	90	7	IPR001870
Domain	B302_SPRY	TRIM49 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B TRIM48	3.73e-07	95	90	7	PS50188
Domain	SPRY	TRIM49 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B	3.90e-06	87	90	6	SM00449
Domain	Ank_2	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	9.34e-06	215	90	8	PF12796
Domain	Ank	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	1.43e-05	228	90	8	PF00023
Domain	BBOX	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	2.05e-05	69	90	5	SM00336
Domain	Butyrophylin	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	2.20e-05	70	90	5	IPR003879
Domain	-	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	2.35e-05	71	90	5	4.10.45.10
Domain	zf-B_box	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	2.52e-05	72	90	5	PF00643
Domain	-	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	2.62e-05	248	90	8	1.25.40.20
Domain	ANK	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	2.85e-05	251	90	8	SM00248
Domain	ANK_REPEAT	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	3.02e-05	253	90	8	PS50088
Domain	Ankyrin_rpt-contain_dom	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	3.11e-05	254	90	8	IPR020683
Domain	ANK_REP_REGION	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	3.11e-05	254	90	8	PS50297
Domain	Ankyrin_rpt	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	3.87e-05	262	90	8	IPR002110
Domain	ZF_BBOX	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	4.20e-05	80	90	5	PS50119
Domain	Znf_B-box	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	4.46e-05	81	90	5	IPR000315
Domain	Actin_CS	POTEE POTEF POTEI	5.79e-05	16	90	3	IPR004001
Domain	ACTINS_2	POTEE POTEF POTEI	7.01e-05	17	90	3	PS00432
Domain	Actin/actin-like_CS	POTEE POTEF POTEI	8.38e-05	18	90	3	IPR020902
Domain	ConA-like_dom	TRIM49 CLSTN3 RNF123 TRIM49C TRIM49D1 HERC1 TRIM49B	9.07e-05	219	90	7	IPR013320
Domain	Leu-rich_rpt_Cys-con_subtyp	NLRC5 FBXL17 KDM2B	9.92e-05	19	90	3	IPR006553
Domain	LRR_CC	NLRC5 FBXL17 KDM2B	9.92e-05	19	90	3	SM00367
Domain	ACTINS_ACT_LIKE	POTEE POTEF POTEI	9.92e-05	19	90	3	PS01132
Domain	FBOX	CCNF FBXL18 FBXL17 KDM2B	1.14e-04	52	90	4	SM00256
Domain	LRR_6	LRRC42 TONSL NLRC5 FBXL17	1.43e-04	55	90	4	PF13516
Domain	7TM_GPCR_Srsx	ADRA1D HTR1A ADRA2B MC1R MC4R	2.08e-04	112	90	5	SM01381
Domain	F-box	CCNF FBXL18 FBXL17 KDM2B	3.06e-04	67	90	4	PF00646
Domain	-	ZFYVE28 TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 KDM2B TRIM49B TRIM48	3.12e-04	449	90	9	3.30.40.10
Domain	Melcrt_ACTH_rcpt	MC1R MC4R	3.40e-04	6	90	2	IPR001671
Domain	Znf_RING/FYVE/PHD	ZFYVE28 TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 KDM2B TRIM49B TRIM48	3.67e-04	459	90	9	IPR013083
Domain	FBOX	CCNF FBXL18 FBXL17 KDM2B	4.04e-04	72	90	4	PS50181
Domain	Actin	POTEE POTEF POTEI	4.41e-04	31	90	3	IPR004000
Domain	Actin	POTEE POTEF POTEI	4.41e-04	31	90	3	PF00022
Domain	ACTIN	POTEE POTEF POTEI	4.41e-04	31	90	3	SM00268
Domain	F-box_dom	CCNF FBXL18 FBXL17 KDM2B	4.72e-04	75	90	4	IPR001810
Domain	ZF_RING_2	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 TRIM49B TRIM48	5.92e-04	298	90	7	PS50089
Domain	RING	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 TRIM49B TRIM48	6.79e-04	305	90	7	SM00184
Domain	Znf_RING	TRIM49 RNF123 TRIM49C TRIM49D1 RNF225 TRIM49B TRIM48	1.00e-03	326	90	7	IPR001841
Domain	ADR_fam	ADRA1D ADRA2B	1.01e-03	10	90	2	IPR002233
Domain	PKD_channel	MCOLN1 MCOLN2	1.23e-03	11	90	2	PF08016
Domain	PKD1_2_channel	MCOLN1 MCOLN2	1.23e-03	11	90	2	IPR013122
Domain	AA_permease_2	SLC7A2 SLC7A7	1.73e-03	13	90	2	PF13520
Domain	AA/rel_permease1	SLC7A2 SLC7A7	1.73e-03	13	90	2	IPR002293
Domain	PI3/4_kinase_CS	PIK3C2B ATM	2.31e-03	15	90	2	IPR018936
Domain	-	PIK3C2B ATM	2.64e-03	16	90	2	1.10.1070.11
Domain	PI3Kc	PIK3C2B ATM	2.64e-03	16	90	2	SM00146
Domain	ZF_RING_1	TRIM49 RNF123 TRIM49C RNF225 TRIM49B TRIM48	2.83e-03	291	90	6	PS00518
Domain	PI3/4_kinase_cat_dom	PIK3C2B ATM	3.34e-03	18	90	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C2B ATM	3.34e-03	18	90	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C2B ATM	3.34e-03	18	90	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C2B ATM	3.34e-03	18	90	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C2B ATM	3.34e-03	18	90	2	PS00916
Domain	AA-permease/SLC12A_dom	SLC7A2 SLC7A7	4.98e-03	22	90	2	IPR004841
Domain	CD20-like	TMEM212 TMEM176A	4.98e-03	22	90	2	IPR007237
Domain	AA_permease	SLC7A2 SLC7A7	4.98e-03	22	90	2	PF00324
Domain	CD20	TMEM212 TMEM176A	4.98e-03	22	90	2	PF04103
Domain	ARM-type_fold	WAPL PIK3C2B ARFGEF2 ATM ECPAS AGBL1	5.94e-03	339	90	6	IPR016024
Domain	TAS2R	TAS2R4 TAS2R38	6.92e-03	26	90	2	PF05296
Domain	T2R	TAS2R4 TAS2R38	6.92e-03	26	90	2	IPR007960
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEE POTEM POTEF POTEG POTEI	4.02e-10	15	95	5	16824795
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM49B TRIM48	6.97e-08	15	95	4	19703589
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49D1 TRIM49B	1.96e-07	19	95	4	22144910
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEE POTEM POTEI	1.64e-06	9	95	3	16364570
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	ZFYVE28 POTEE POTEM POTEF POTEG POTEI	5.95e-06	163	95	6	24316575
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEE POTEF	7.38e-06	2	95	2	19669888
Pubmed	Differential Activation of TAS2R4 May Recover Ability to Taste Propylthiouracil for Some TAS2R38 AVI Homozygotes.	TAS2R4 TAS2R38	7.38e-06	2	95	2	38732607
Pubmed	The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1.	MCOLN1 MCOLN2	7.38e-06	2	95	2	19763610
Pubmed	The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.	MCOLN1 MCOLN2	7.38e-06	2	95	2	18794901
Pubmed	ADRA2B and HTR1A: An Updated Study of the Biogenic Amine Receptors Reveals Novel Conserved Motifs Which Play Key Role in Mental Disorders.	HTR1A ADRA2B	7.38e-06	2	95	2	37525034
Pubmed	Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.	FLT1 TIMP2	7.38e-06	2	95	2	23415672
Pubmed	Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors.	MC1R MC4R	7.38e-06	2	95	2	12244039
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DIP2A FLT1 WAPL PIK3C2B ATM ADGRF3 HERC1 ECPAS BAG6	9.16e-06	497	95	9	36774506
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	TRIM49 TRIM49C TRIM49B TRIM48	1.60e-05	55	95	4	19468303
Pubmed	Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1.	MCOLN1 MCOLN2	2.21e-05	3	95	2	16606612
Pubmed	Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy.	MCOLN1 MCOLN2	2.21e-05	3	95	2	20736310
Pubmed	Behavioral analysis of Drosophila transformants expressing human taste receptor genes in the gustatory receptor neurons.	TAS2R4 TAS2R38	2.21e-05	3	95	2	22794107
Pubmed	Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.	MC1R UBAC2	2.21e-05	3	95	2	21700618
Pubmed	Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children.	MC1R MC4R	2.21e-05	3	95	2	11487744
Pubmed	A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.	MC1R MC4R	2.21e-05	3	95	2	12165561
Pubmed	Functional multimerization of mucolipin channel proteins.	MCOLN1 MCOLN2	2.21e-05	3	95	2	19885840
Pubmed	Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells.	MC1R MC4R	2.21e-05	3	95	2	16081629
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEE POTEF	2.21e-05	3	95	2	17101985
Pubmed	A novel MC4R deletion coexisting with FTO and MC1R gene variants, causes severe early onset obesity.	MC1R MC4R	2.21e-05	3	95	2	27394708
Pubmed	Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.	MC1R MC4R	2.21e-05	3	95	2	19737927
Pubmed	Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.	MC1R MC4R	2.21e-05	3	95	2	7935841
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ZFYVE28 POTEE DIP2A ADRA1D RNF123 DQX1 ADGRB1 ATM ECPAS NUP205	3.40e-05	736	95	10	29676528
Pubmed	Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.	MC1R ATM	4.41e-05	4	95	2	19524511
Pubmed	Novel binding motif of ACTH analogues at the melanocortin receptors.	MC1R MC4R	4.41e-05	4	95	2	19743876
Pubmed	Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.	MCOLN1 MCOLN2	4.41e-05	4	95	2	30479274
Pubmed	Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.	MC1R MC4R	4.41e-05	4	95	2	15470082
Pubmed	Deficiency of ataxia telangiectasia mutated kinase modulates cardiac remodeling following myocardial infarction: involvement in fibrosis and apoptosis.	TIMP2 ATM	7.34e-05	5	95	2	24358288
Pubmed	Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.	TAS2R4 TAS2R38	7.34e-05	5	95	2	15886333
Pubmed	Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis.	MC1R MC4R	7.34e-05	5	95	2	12865302
Pubmed	Molecular cloning, expression, and characterization of a fifth melanocortin receptor.	MC1R MC4R	7.34e-05	5	95	2	8185570
Pubmed	Mucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaning.	MCOLN1 MCOLN2	7.34e-05	5	95	2	25521295
Pubmed	Biphasic effect of melanocortin agonists on metabolic rate and body temperature.	MC1R MC4R	1.10e-04	6	95	2	24981835
Pubmed	Expression of adrenergic receptors in mouse preimplantation embryos and ovulated oocytes.	ADRA1D ADRA2B	1.10e-04	6	95	2	17636168
Pubmed	Melanocortin receptor binding determinants in the agouti protein.	MC1R MC4R	1.10e-04	6	95	2	9454589
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEM POTEG	1.10e-04	6	95	2	17171436
Pubmed	α1-Adrenergic Receptors Function Within Hetero-Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C-X-C motif) Receptor 4 in Vascular Smooth Muscle Cells.	ADRA1D ADRA2B	1.10e-04	6	95	2	28862946
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	WAPL PIK3C2B DOCK7 ARFGEF2 BAG6 NUP205	1.43e-04	288	95	6	23383273
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEE POTEG	1.54e-04	7	95	2	15276201
Pubmed	MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.	MC1R MC4R	1.54e-04	7	95	2	19329486
Pubmed	Effects of recombinant agouti-signaling protein on melanocortin action.	MC1R MC4R	1.54e-04	7	95	2	9058374
Pubmed	RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.	ATM BAG6	1.54e-04	7	95	2	36563124
Pubmed	The structure and evolution of the melanocortin and MCH receptors in fish and mammals.	MC1R MC4R	1.54e-04	7	95	2	12620396
Pubmed	Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human.	MC1R MC4R	2.05e-04	8	95	2	7949735
Pubmed	Cardiac function in genetically engineered mice with altered adrenergic receptor signaling.	ADRA1D ADRA2B	2.05e-04	8	95	2	9139936
Pubmed	Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis.	ATM NOBOX	2.05e-04	8	95	2	23759310
Pubmed	Agouti/melanocortin interactions with leptin pathways in obesity.	MC1R MC4R	2.05e-04	8	95	2	9763877
Pubmed	Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.	FLT1 TIMP2 ADGRB1	2.10e-04	42	95	3	29438518
Pubmed	Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo.	ADRA1D ADRA2B	2.62e-04	9	95	2	21209093
Pubmed	Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.	ADRA2B PIK3C2B ABCC8 MC4R	3.06e-04	117	95	4	18996102
Pubmed	The mahogany protein is a receptor involved in suppression of obesity.	ADRA1D ADRA2B	3.28e-04	10	95	2	10086355
Pubmed	Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.	ZFYVE28 NLRC5	4.00e-04	11	95	2	23212062
Pubmed	gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.	UBAC2 BAG6	4.00e-04	11	95	2	26424800
Pubmed	Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.	CCNF FBXL18 FBXL17	4.67e-04	55	95	3	37028429
Pubmed	The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion.	ABCC8 DIO3	4.79e-04	12	95	2	21828183
Pubmed	An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.	DOCK7 ATM	5.65e-04	13	95	2	30254148
Pubmed	IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.	TNFSF13B ATM	5.65e-04	13	95	2	28137874
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXL18 FBXL17 KDM2B	6.33e-04	61	95	3	15520277
Pubmed	Genome-wide association study identifies three new melanoma susceptibility loci.	MC1R ATM	6.58e-04	14	95	2	21983787
Pubmed	B Cell and BAFF dependence of IFN-α-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice.	TNFSF13B IFNA2	6.58e-04	14	95	2	21383240
Pubmed	Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases.	CCNF FBXL18 FBXL17	6.64e-04	62	95	3	29103612
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	ATM HERC1 ECPAS MCOLN1	7.80e-04	150	95	4	32423001
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP8 CLSTN3 ITSN2 DOCK7 ZDHHC17 FHIP2A	8.96e-04	407	95	6	12693553
Pubmed	A molecular analysis of matrix remodeling and angiogenesis during long bone development.	FLT1 TIMP2	9.78e-04	17	95	2	11165481
Pubmed	Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice.	FLT1 ADRA2B	9.78e-04	17	95	2	17673674
Pubmed	A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131.	TAS2R4 TAS2R38	9.78e-04	17	95	2	24367558
Pubmed	PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.	CCNF KDM2B	1.10e-03	18	95	2	28614300
Pubmed	Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.	CD93 ADGRB1	1.10e-03	18	95	2	33927296
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	TRIM49 TRIM49C TRIM49D1	1.39e-03	80	95	3	16554811
Pubmed	Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution.	ADRA1D HTR1A	1.50e-03	21	95	2	1676978
Pubmed	Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.	RNF123 BAG6	1.65e-03	22	95	2	24981174
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R4 TAS2R38	1.65e-03	22	95	2	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R4 TAS2R38	1.80e-03	23	95	2	20022913
Pubmed	Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.	MC1R DOCK7 ECPAS	1.89e-03	89	95	3	27034005
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	RNF123 PIK3C2B ITSN2 UBAC2 HERC1 BAG6	2.09e-03	481	95	6	28190767
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	MCOLN1 MCOLN2	2.13e-03	25	95	2	16382100
Pubmed	Receptors for bitter and sweet taste.	TAS2R4 TAS2R38	2.13e-03	25	95	2	12139982
Pubmed	Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature.	PDE2A DIO3	2.13e-03	25	95	2	38521877
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R4 TAS2R38	2.30e-03	26	95	2	11696554
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEE POTEF POTEI	2.35e-03	96	95	3	23580065
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R4 TAS2R38	2.48e-03	27	95	2	12581520
Pubmed	Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.	FLT1 CDK5R1	2.48e-03	27	95	2	27178982
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PDE2A PIK3C2B	2.48e-03	27	95	2	11156964
Pubmed	An introduction to TRP channels.	MCOLN1 MCOLN2	2.48e-03	27	95	2	16460286
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R4 TAS2R38	2.66e-03	28	95	2	15744053
Pubmed	SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.	DOCK7 ALCAM	2.66e-03	28	95	2	32801337
Pubmed	A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure.	HTR1A MC4R	2.66e-03	28	95	2	19737523
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PPP1R3D USP8 RNF123 FAM120B TIMP2 TONSL HERC1 ECPAS BAG6 NUP205	2.68e-03	1284	95	10	17353931
Cytoband	2q21.1	POTEE POTEF POTEI	2.52e-04	58	96	3	2q21.1
Cytoband	14q11.2	POTEM OR5AU1 POTEG SLC7A7	5.73e-04	180	96	4	14q11.2
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEE POTEM POTEF POTEG POTEI	6.99e-10	13	66	5	685
GeneFamily	Ankyrin repeat domain containing	POTEE POTEM POTEF ASB10 POTEG TONSL POTEI ZDHHC17	2.70e-06	242	66	8	403
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM48	2.50e-05	95	66	5	59
GeneFamily	F-box and leucine rich repeat proteins	FBXL18 FBXL17 KDM2B	5.90e-05	21	66	3	558
GeneFamily	Melanocortin receptors	MC1R MC4R	1.30e-04	5	66	2	236
GeneFamily	Adrenoceptors	ADRA1D ADRA2B	4.65e-04	9	66	2	169
GeneFamily	Ring finger proteins	TRIM49 RNF123 TRIM49C TRIM49D1 TRIM49B TRIM48	4.96e-04	275	66	6	58
GeneFamily	Transient receptor potential cation channels	MCOLN1 MCOLN2	4.67e-03	28	66	2	249
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CD93 NAT8L FLT1 PIK3C2B ADGRF3 DKK2	1.88e-06	172	95	6	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	facs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 NAT8L TMEM176A RNF225 ALCAM TAS2R38	2.21e-06	177	95	6	35d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEE POTEF POTEG POTEI	1.01e-05	63	95	4	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UTP15 PIK3C2B FAM131A ATM SLC7A7	3.67e-05	175	95	5	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 SMIM9 TMEM54 ABCC8 ALCAM	3.67e-05	175	95	5	0992de1c7bffcb6890584357a7a0a8955927da6c
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9\|TCGA-Breast / Sample_Type by Project: Shred V9	POTEE POTEM POTEF POTEI	4.15e-05	90	95	4	96e836c7a1df279ac812b7c3aa75e6b81b614244
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE POTEF POTEG SMIM5 POTEI	4.20e-05	180	95	5	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE POTEF POTEG SMIM5 POTEI	4.20e-05	180	95	5	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	4.54e-05	183	95	5	4763df29c888d47c22076803b054f06b4cc29368
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	4.54e-05	183	95	5	fcb0f755382d88fb207fc2322cd224c09c6e2ea6
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TNFSF13B EDARADD TMEM176A KDM2B MCOLN2	4.78e-05	185	95	5	7e3d9f5050e71e91021245c11101e994ae41d22b
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 TMEM54 ABCC8 TMEM212 SMIM5	4.91e-05	186	95	5	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	NAT8L TNFSF13B SMIM5 ZDHHC17 MCOLN2	5.03e-05	187	95	5	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	Endothelial-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CD93 FLT1 PDE2A SMIM9 DKK2	5.56e-05	191	95	5	f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ZFYVE28 CD93 FLT1 PDE2A NLRC5	5.70e-05	192	95	5	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	5.70e-05	192	95	5	f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	5.70e-05	192	95	5	0219093e7921a0db78053aee13ec480b520f5662
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	5.84e-05	193	95	5	69352551ad5db325ac0d6df2ac1e35ae473ac01f
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD93 FLT1 PDE2A CLSTN3 GDF3	5.84e-05	193	95	5	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	Healthy-Classical_Monocyte\|World / disease group, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.14e-05	195	95	5	0d96f456cc84ebb2543406fb2374c6d7cedd3c4d
ToppCell	BLOOD--(3)_Classical_Mono-1\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.14e-05	195	95	5	4702d234731d4cd47d5fba570e439deee21c67f9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.14e-05	195	95	5	9f7dc9328d244291baf92b03c346c2189b58e7c4
ToppCell	Endothelial-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CD93 FLT1 PIK3C2B ABCC8 DKK2	6.14e-05	195	95	5	c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell	Healthy-Classical_Monocyte\|Healthy / disease group, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	27d24aa2fd4521cf7e410688ed3b11b2d9700dd2
ToppCell	VE-granulo1-\|VE / Condition, Cell_class and T cell subcluster	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	ab3f2ce294c7e503d86254a195be0cf500a2c5e4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	76101d5ebe2a74c0a0a885ec31c3c1847bda8a7b
ToppCell	myeloid-CD14+_Monocyte\|World / Lineage and Cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	b70f9402a1707671c0dd44226fa2adfc4bde8283
ToppCell	VE-granulo1\|VE / Condition, Cell_class and T cell subcluster	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	6dbd3acb30173d7f0b7bca0a82f435f00ca85835
ToppCell	(7)_Monocyte\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	0232167559dcd2d86ee8b78017cf5f2a084b2cb7
ToppCell	(7)_MNP-(7)_Monocyte\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	4c2ea16352ba3482c02c03866460e0d975f9fc99
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.29e-05	196	95	5	b6cadb2098b0997d205903beb8a6992c5f692642
ToppCell	COVID-granulo1-\|COVID / Condition, Cell_class and T cell subcluster	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	190392117dc6269a21983bd3e554066fd48acd5e
ToppCell	control-Classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	881d173f6c69efc426679832d917c639d9394098
ToppCell	normal-na-Myeloid-classical_monocyte-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	dc53d1c0d226ca22291a489c38e08a7ccdc3aeeb
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DIP2A DLG5 NLRC5 ATM SLC23A3	6.44e-05	197	95	5	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	COVID-granulo1\|COVID / Condition, Cell_class and T cell subcluster	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	4cd774d9d5a6bf7729dc6b7bcd3ddfe3f3051ada
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	a1d42d0177630e08f36a96a6272f796244c1a319
ToppCell	Influenza_Severe-Classical_Monocyte\|World / Disease group and Cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	e9a01f0fbbeaf6b23bce4603f62053c003848da4
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	bb0d814d88a14199eb8ab2b3bd67511b19e3ab5d
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	6e96a6c2576f52b72aeab1e41f47a0af05ff327a
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	a80be1081f3ed0aceea69a33be21bca6bc354472
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	TIMP2 TNFSF13B TMEM176A SLC7A7 MCOLN1	6.44e-05	197	95	5	dcf1e74b7c21466d38d68f44d404bce14ade2805
ToppCell	normal-na-Myeloid-classical_monocyte\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	b98ceb82fe2126bbeb2df87a7243be0f2c0ccfa8
ToppCell	mild_COVID-19-Classical_Monocyte\|World / disease group, cell group and cell class (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	5d826f4d7b7a46847c67e6bef38eb860bc808a6c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	c5da3e183e2609aead5433d3dae19a2a33a42ecc
ToppCell	(7)_MNP\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.44e-05	197	95	5	6790346736946984cc80d67668523ba70ab0b380
ToppCell	mild-pDC\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NAT8L SMIM5 ALCAM ZDHHC17 MCOLN2	6.44e-05	197	95	5	15230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|World / Lineage, cell class and subclass	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	2528062d1646746b2e7d6b0ec38f8cfabf3df18f
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	03ba8bf87bb2b7aaa560ccca95636cb1d11d5ead
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	45c6c1156ee41db051b873022a8a074f5730e95a
ToppCell	BLOOD--(3)_Classical_Mono-2\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	34c23181c227f65209cde4382248253282f6ac6e
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	cf0fda1a24449cfd8ed56ffc7841d8accb187949
ToppCell	10x5'-lymph-node_spleen-Myeloid_Monocytic\|lymph-node_spleen / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	2541f1095ed91e6789cb888cf39a208b8107726a
ToppCell	Int-URO-Myeloid\|Int-URO / Disease, Lineage and Cell Type	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	895ec2ec9f46a96a5d489beded8f05ca5b860a8d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CD93 FLT1 PDE2A TIMP2 DKK2	6.60e-05	198	95	5	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	remission-Classical_Monocyte\|remission / disease stage, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	d620ea1ee4e1b47a71059695df6c2b4793236ebc
ToppCell	Multiple_Sclerosis-Myeloid\|Multiple_Sclerosis / Disease, Lineage and Cell Type	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	3c2817d95011ae372d0316ccf774e975536207b0
ToppCell	PBMC-Convalescent-Myeloid\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	3973bbc1bfb5b08dd1becd5e4bb5899b15df9e55
ToppCell	COVID-19_Convalescent-Myeloid-Classical_Monocyte\|COVID-19_Convalescent / Disease group, lineage and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	ca58c62d7f732631af1f7cabaa785757d031c011
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	1b14f7eaf3e2805ca9efbebad4e670329db74dc9
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	7e1f08dae11a7cc7949a5622d82c7e6660d06dea
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	525adc91fd8f2ad957b1879a5bf3950baa7d5ef8
ToppCell	10x5'-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	934dacb67d71faa2f8732c39d7f8e64b0ee75396
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TMEM176A ALCAM SLC7A7	6.60e-05	198	95	5	94e2567f057b2c455a9656b121321a28e7cb1d2b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TMEM176A ALCAM SLC7A7	6.60e-05	198	95	5	f3a12a7e23bb4ff6e82fee675dbc090d99587f69
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	d3c1ffb8f40d4f14b3dc9dd08c7cd73376bf9f65
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	7ee8a3ea7ece300fcb8523561770a792a6c3ebd8
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	708f9644362d300ecc477d76208e4957bb92487e
ToppCell	COVID-19_Severe-Myeloid-Classical_Monocyte\|COVID-19_Severe / Disease group, lineage and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	dfe92577c7d1e63315c7564d5d99362c6e7d4d46
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	0128d00e6c3f99a026329dd169c0ea5e0e24c59c
ToppCell	BLOOD--(3)_MNP\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	4bba020c2bef7f4cc0c9237644f5a39398039286
ToppCell	COVID-19_Convalescent-Myeloid\|COVID-19_Convalescent / Disease group, lineage and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	20016bfa7e651f3d22d6148469737b50369c149b
ToppCell	myeloid\|World / Lineage, cell class and subclass	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	67334ca0ec4a5070d8ddaecffb84e7437bf77765
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	e2ead6886548638f94e9302b8eb8d797ce454d41
ToppCell	Control-Myeloid-Classical_Monocyte\|Control / Disease group, lineage and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	2b361d531c16e7a2d4cf676abb4421035d9bfe6e
ToppCell	myeloid-Monocyte\|World / Lineage, cell class and subclass	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	ab60faa27ab1f6c510154311d9658d770189f17b
ToppCell	Multiple_Sclerosis-Myeloid-CD14_Mono\|Multiple_Sclerosis / Disease, Lineage and Cell Type	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	128969698b2b0468cf5374f695e2d9fd02227d13
ToppCell	remission-Classical_Monocyte\|World / disease stage, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	056b8745e753b1a500cf58d09a2ebf38707e1357
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	9411067b96eca5e6f1a241f3e9419f78d0448214
ToppCell	mild_COVID-19-Classical_Monocyte\|mild_COVID-19 / disease group, cell group and cell class (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	5b31b6e008e05d6528656114fbe0ccae8ffe13b1
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	711618d47281c07e89723482c28570449eb7c626
ToppCell	10x5'-Liver-Myeloid_Monocytic\|Liver / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	d0925948bf667545fb0b343e2fc80f7379e433e3
ToppCell	10x5'-blood-Myeloid_Monocytic\|blood / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	c0985fff359c78d0fc1b6f31885aa168c9f5fdae
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	f7182ab009e8119268d1be5d3ccff516af8732e8
ToppCell	Control-Myeloid-CD14_Mono\|Control / Disease, Lineage and Cell Type	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	c8d88671d47b87a101749b3f4ab90a28f9b6bc72
ToppCell	BLOOD--(3)_Intermediate_monocytes\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	61685a86f70a7d2a6d3260b76081119978c15661
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	abfef06ce9e400094de4e3fd809b09f83ad02db5
ToppCell	PBMC-Convalescent-Myeloid\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	7e348a21c0ad6e15b4d2a58810428ab28ff8ff47
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD93 FLT1 SMIM9 PIK3C2B DKK2	6.60e-05	198	95	5	002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-classical_monocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.60e-05	198	95	5	a85894aa7899e2732a3cf4cbfadc5ca395cbcacf
ToppCell	Influenza_Severe-Classical_Monocyte\|Influenza_Severe / Disease group and Cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	077ace6e0faedb8c701fcb227427204678867237
ToppCell	control-Classical_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	171ccbd498774911143d55a27feeec745a0a7122
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	4fc03377c017209111561789226621d258291481
ToppCell	Healthy_donor-Classical_Monocyte\|World / disease group, cell group and cell class (v2)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	45e9099a13becb1e235435ceaaffb92b82ce34ee
ToppCell	IIF-Myeloid-CD14_Mono\|IIF / Disease, Lineage and Cell Type	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	accfb3d8ad3f03f9302f2056ca16c1be6231a351
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic\|bone_marrow / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	62b0861faf173eead75678aad10d396cd0d80c2c
ToppCell	10x5'-Liver-Myeloid_Monocytic-Classical_monocytes\|Liver / Manually curated celltypes from each tissue	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	46491e8e76aa4d7ada036946f93cf71609c85462
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TNFSF13B TMEM176A SLC7A7	6.75e-05	199	95	5	0e67257f1ecf90f80e6524d70d38b3733e953b4e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD93 TIMP2 TMEM176A ALCAM SLC7A7	6.75e-05	199	95	5	97af159fa3a5533ec3d45331fb80c6da8a715aa5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Intermediate\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	NAT8L TNFSF13B ARFGEF2 NLRC5 FBXL17	6.75e-05	199	95	5	cf592d93612023a13de21e0fb8c6b13714f9af71
Drug	L-659,066	ADRA1D HTR1A ADRA2B	7.03e-06	10	90	3	CID000163952
Drug	AH 21-132	PDE2A HTR1A MC1R MC4R	1.36e-05	37	90	4	CID003035793
Drug	Saphris	FLT1 ADRA1D HTR1A ADRA2B	2.07e-05	41	90	4	CID000163091
Drug	MK-912	ADRA1D HTR1A ADRA2B	2.11e-05	14	90	3	CID000123679
Drug	fluparoxan	ADRA1D HTR1A ADRA2B	3.22e-05	16	90	3	CID000072036
Drug	R-5	HTR1A LMLN MC4R	3.22e-05	16	90	3	CID011742733
Drug	efaroxan	ADRA1D HTR1A ADRA2B ABCC8	3.28e-05	46	90	4	CID000072016
Drug	Ergot	ADRA1D HTR1A ADRA2B CREB3	3.89e-05	48	90	4	CID000003250
Drug	Pergolide	ADRA1D HTR1A ADRA2B	3.90e-05	17	90	3	DB01186
Drug	imiloxan	ADRA1D HTR1A ADRA2B	3.90e-05	17	90	3	CID000133621
Drug	naftopidil	ADRA1D HTR1A ADRA2B	3.90e-05	17	90	3	CID000004418
Drug	Bromocriptine	ADRA1D HTR1A ADRA2B	4.67e-05	18	90	3	DB01200
Drug	benalfocin	ADRA1D HTR1A ADRA2B	5.53e-05	19	90	3	CID000123981
Drug	GBR 12935	HTR1A ADRA2B MC1R	6.49e-05	20	90	3	CID000003456
Drug	methylparaben	PDE2A MED29 PORCN	6.49e-05	20	90	3	CID000007456
Drug	Doxepin	ADRA1D HTR1A ADRA2B	6.49e-05	20	90	3	DB01142
Drug	midaglizole	ADRA1D ADRA2B ABCC8	6.49e-05	20	90	3	CID000068864
Drug	ARC 239	ADRA1D HTR1A ADRA2B	7.54e-05	21	90	3	CID000609483
Drug	benoxathian	ADRA1D HTR1A ADRA2B	8.71e-05	22	90	3	CID000002325
Drug	1-ephedrine	FLT1 ADRA1D ADRA2B DKK2	8.80e-05	59	90	4	CID000005032
Drug	5-methylurapidil	ADRA1D HTR1A	9.22e-05	4	90	2	ctd:C057446
Drug	guanfacine	ADRA1D HTR1A ADRA2B	1.29e-04	25	90	3	CID000003519
Drug	BRL 44408	ADRA1D HTR1A ADRA2B	1.29e-04	25	90	3	CID000121850
Drug	AC1L1I3V	ADRA1D ADRA2B PORCN	1.29e-04	25	90	3	CID000004411
Drug	Quetiapine	ADRA1D HTR1A ADRA2B	1.45e-04	26	90	3	DB01224
Drug	5-methylgramine	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000034855
Drug	Leniquinsin	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000025195
Drug	metazosin	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000093514
Drug	S-10089	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000146399
Drug	AC1O6ABX	ADRA1D ADRA2B	1.53e-04	5	90	2	CID006449894
Drug	CS-263	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000137303
Drug	KABI 2023	ADRA1D ADRA2B	1.53e-04	5	90	2	CID000192124
Drug	hydergin	HTR1A ATM	1.53e-04	5	90	2	CID000592735
Drug	A-53693	ADRA1D ADRA2B	1.53e-04	5	90	2	CID003082713
Drug	embitol	MC1R MC4R	1.53e-04	5	90	2	CID000005928
Disease	neutropenia, leukopenia, chemotherapy-induced cytotoxicity measurement	TNFSF13B NLRC5	8.01e-06	2	84	2	EFO_0004233, EFO_0010978, MONDO_0001475
Disease	mucolipidosis type IV (implicated_via_orthology)	MCOLN1 MCOLN2	2.40e-05	3	84	2	DOID:0080490 (implicated_via_orthology)
Disease	glycoproteinosis (implicated_via_orthology)	MCOLN1 MCOLN2	4.79e-05	4	84	2	DOID:3343 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	FLT1 PDE2A ITSN2 ARFGEF2 NLRC5 DIO3 FAM131A ATM SLC7A7 MCOLN1 IFNA2	2.31e-04	1074	84	11	C0006142
Disease	response to hydrochlorothiazide, triglyceride measurement	GDF3 AGBL1 EGFEM1P	3.30e-04	47	84	3	EFO_0004530, EFO_0005202
Disease	thyroid gland carcinoma (is_marker_for)	CD93 FLT1	5.19e-04	12	84	2	DOID:3963 (is_marker_for)
Disease	cardiomyopathy (biomarker_via_orthology)	PDE2A TIMP2	6.12e-04	13	84	2	DOID:0050700 (biomarker_via_orthology)
Disease	melanoma	FLT1 MC1R ATM FHIP2A IFNA2	7.25e-04	248	84	5	C0025202
Disease	electroencephalogram measurement	TMEM212 SLC7A7 DKK2	1.25e-03	74	84	3	EFO_0004357
Disease	abnormal paneth cell measurement	ADRA1D FBXL17	1.33e-03	19	84	2	EFO_0007963
Disease	feeling "fed-up" measurement	RNF123 ITSN2 TRIM48	1.35e-03	76	84	3	EFO_0009588
Disease	Depressive disorder	RNF123 HTR1A MC1R MC4R IFNA2	1.43e-03	289	84	5	C0011581
Disease	diet measurement, fasting blood insulin measurement	HTR1A AGBL1	1.78e-03	22	84	2	EFO_0004466, EFO_0008111
Disease	diet measurement, HOMA-IR	HTR1A AGBL1	1.95e-03	23	84	2	EFO_0004501, EFO_0008111
Disease	cardiovascular disease	ADRA1D WAPL MC4R DOCK7 KDM2B TRIM48	1.96e-03	457	84	6	EFO_0000319
Disease	Anhedonia	HTR1A MC4R	2.12e-03	24	84	2	C0178417
Disease	visceral adipose tissue measurement	HTR1A PIK3C2B MC4R FBXL17 ALCAM ZDHHC17	2.53e-03	481	84	6	EFO_0004765
Disease	Myocardial Infarction	TIMP2 ATM IFNA2	2.55e-03	95	84	3	C0027051
Disease	Fever	HTR1A IFNA2	2.68e-03	27	84	2	C0015967

Protein segments in the cluster

Peptide	Gene	Start	Entry
STLLLAVETLACSLC	ADGRF3	581	Q8IZF5
ASTSELLRCLGEFLC	CDK5R1	146	Q15078
LPLLLASLLASCSCN	CLSTN3	6	Q9BQT9
TFVALSDLRCNLACT	BAG6	336	P46379
CLCDRLSTFAILAQL	ADGRB1	921	O14514
AEATTARCLQLCSLL	ASB10	266	Q8WXI3
LLKQETSSLACCLRI	ARFGEF2	1651	Q9Y6D5
CISKRCVSLLLDLSQ	CD93	136	Q9NPY3
CTSSIVHLCAISLDR	ADRA2B	96	P18089
SESLCERILDSSCSL	ACSS2	196	Q9NR19
RSKDSSCCLLLLAAV	DKK2	6	Q9UBU2
TLDSLEDTKLCRCLS	SLC7A2	21	P52569
CLGLLILELKSASCS	AGBL1	1036	Q96MI9
DDSVLQCLLSLLSCL	ITSN2	626	Q9NZM3
FICCLALSDLLVSGS	MC1R	76	Q01726
FIIRCSLCALETLKS	NOBOX	56	O60393
RAKLLSLCSFIIETC	NUP205	1886	Q92621
ILTCSLSFLLCARSL	MCOLN1	306	Q9GZU1
TQTLRSAALEDCALC	ZFYVE28	776	Q9HCC9
LAVCCGSASIVSLLL	POTEF	311	A5A3E0
LLLHSLRLCAQTASC	DIO3	31	P55073
LANALAACCLSSRLS	HERC1	3366	Q15751
LTRALPLDLCSCSSS	LMLN	616	Q96KR4
PLDLCSCSSSLVVTL	LMLN	621	Q96KR4
TCARLRCSLHASLLV	GDF3	221	Q9NR23
CLTSECRVLLIESLA	ECPAS	1806	Q5VYK3
ETRASRCCLLLVSED	PDE2A	256	O00408
ECESLLRSCQDSLTL	DLG5	776	Q8TDM6
SFRELTCLDLSCCKL	LRRC42	171	Q9Y546
LELCLRLAHECLSQS	MED29	116	Q9NX70
LCASLALGSAECVLL	OR2I1P	101	Q8NGU4
LCCESLSREVESLLL	DQX1	276	Q8TE96
VSSLTLLIRFLCCSQ	MAS1L	241	P35410
DLSSNSICVSTLLCL	NLRC5	776	Q86WI3
SICVSTLLCLARVAV	NLRC5	781	Q86WI3
LTFTCNCSSTVDLLI	PIK3C2B	391	O00750
LAVCCGSASIVSLLL	POTEE	311	Q6S8J3
MAAACRCLSLLLLST	PPY2P	1	Q9NRI7
SLALALLCLVLSTCV	PORCN	196	Q9H237
VSLRSFSLCCDLLSQ	ATM	1486	Q13315
ALCSSSCPLLRTLDV	KDM2B	1166	Q8NHM5
ADLCLRLLRHCSSSI	DOCK7	1551	Q96N67
RTQHLCSFLCELSLL	CCNF	426	P41002
TITCENCRLLSCIDS	ERVK-7	291	P61567
STSNCLLVLISVDRC	GPR32P1	126	Q8NGA4
LSLDERCLSASLVCK	FBXL17	336	Q9UF56
RLSGSLLTCCLRLTV	CEP250	211	Q9BV73
DTLCSSLCSLEDGLL	FAM131A	251	Q6UXB0
LFIALDVLCCTSSIL	HTR1A	111	P08908
ALLVALLVLSCKSSC	IFNA2	6	P01563
DSVICSSLLASICSL	MC4R	126	P32245
TCSSCLLRAPTISDL	EDARADD	101	Q8WWZ3
ATSALCRSIKLQCEL	DIP2A	1171	Q14689
QSTCLCELLTDRLAS	FHIP2A	301	Q5W0V3
SSSTCILVLLVSFCL	CREB3	226	O43889
KSCTILRCISLTNLA	EGFEM1P	136	Q0D2K5
ASSCRLLFCLLISAT	ALCAM	6	Q13740
CLASLILCTRSIVLA	MCOLN2	301	Q8IZK6
SLLLEDCQDVTSTCL	FAM120B	631	Q96EK7
LTLALSSCLVLGCFI	OR14I1	196	A6ND48
SNSDCVLLCLSISRL	TAS2R38	51	P59533
VTCLCLSSSGQRLLS	UTP15	251	Q8TED0
EVDRSLLCLLCSSSQ	TRIM48	121	Q8IWZ4
VDRSLLCLLCSSSQE	TRIM49	106	P0CI25
ESALAKLLLTCCSAL	TMEM176A	26	Q96HP8
FTATVLLLLLIACSC	SMIM5	41	Q71RC9
LSLSCVDTSLCEILL	OR5AU1	236	Q8NGC0
DSSILETLVASCCNL	FBXL18	371	Q96ME1
LAVCCGSASIVSLLL	POTEI	311	P0CG38
SLLCVSHLLLLCSLS	SLC23A3	61	Q6PIS1
LSVRSALVCLTCVSA	SLC36A3	371	Q495N2
PSTLECLSRSTLLCV	ABCC8	1136	Q09428
CLSRSTLLCVSALAV	ABCC8	1141	Q09428
DVLCCTASILSLCTI	ADRA1D	176	P25100
SAIIVCLLCELLSSS	TVP23C	46	Q96ET8
LTCLLVDCFSALLSA	PP632	76	Q6XCG6
LDLCLSFTLLCTSLT	TMEM212	151	A6NML5
CALLSLTCALGLLAS	TMEM54	101	Q969K7
VFCLECLARLSLATA	RNF225	86	M0QZC1
FLLCSLTCLLLETVA	SMIM9	11	A6NGZ8
CATCFDLSVSLLRVL	RNF123	1071	Q5XPI4
CLSLCPSLISLDLSA	TONSL	1271	Q96HA7
VDRSLLCLLCSSSQE	TRIM49C	106	P0CI26
AASRLLAAACICLLT	SLC7A7	156	Q9UM01
ASAICCLLLSRTVVE	SERINC4	71	A6NH21
LLATLLRPADACSCS	TIMP2	16	P16035
LNTRCLSVISLATKC	WAPL	671	Q7Z5K2
VLSRLAINSDLCCSS	PPP1R3D	131	O95685
RALALVSCLFLCSLV	SUCO	6	Q9UBS9
GSLDLSIFCSTCLIR	ZDHHC17	431	Q8IUH5
VDRSLLCLLCSSSLE	TRIM49D1	106	C9J1S8
VDRSLLCLLCSSSQE	TRIM49B	106	A6NDI0
RIICLDLKDTFCSSL	UBAC2	61	Q8NBM4
SATLTLLLASSCLLA	nan	196	Q8N1Y9
TLLLALLSCCLTVVS	TNFSF13B	51	Q9Y275
LCALLSCLLLTGSSS	FLT1	11	P17948
LAVCCGSASIVSLLL	POTEG	311	Q6S5H5
LAVCCGSASIVSLLL	POTEM	311	A6NI47
ALSSCLLLACALSAA	TMEM271	11	A0A286YF58
LASTSKCTLQDCLRL	USP8	956	P40818
RLLLACVLISAFTTC	TAS2R4	131	Q9NYW5
ALCFAVSRSLLLTCL	NAT8L	126	Q8N9F0