Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP-kinase scaffold activity	SPAG9 MAP2K1 MAP2K2	1.59e-05	13	78	3	GO:0005078
GeneOntologyMolecularFunction	integrin binding	FAP VWF ADAM20 ITGA6 ITGA1 GPNMB	6.34e-05	175	78	6	GO:0005178
GeneOntologyMolecularFunction	protein tyrosine kinase activity	HIPK3 IGF2R HIPK2 MAP2K1 MAP2K2	2.60e-04	145	78	5	GO:0004713
GeneOntologyMolecularFunction	collagen binding	DPP4 VWF ITGA1 USH2A	2.85e-04	81	78	4	GO:0005518
GeneOntologyCellularComponent	secretory vesicle	SLC6A9 PTPN6 IGF2R VWF MANBA PTPRN SLC15A4 HYAL3 RNF112 ENTPD1 TCIRG1 SYT1 SPAG9 ITGA1 F8	4.19e-05	1246	77	15	GO:0099503
GeneOntologyCellularComponent	lysosomal membrane	GLMP DPP4 CYBRD1 MANBA SLC15A4 TCIRG1 GNB4 SPAG9 SLC39A14	4.96e-05	462	77	9	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	GLMP DPP4 CYBRD1 MANBA SLC15A4 TCIRG1 GNB4 SPAG9 SLC39A14	4.96e-05	462	77	9	GO:0098852
GeneOntologyCellularComponent	secretory granule	SLC6A9 PTPN6 IGF2R VWF MANBA PTPRN SLC15A4 HYAL3 TCIRG1 SYT1 SPAG9 ITGA1 F8	7.80e-05	1014	77	13	GO:0030141
GeneOntologyCellularComponent	vacuolar membrane	GLMP DPP4 CYBRD1 MANBA SLC15A4 TCIRG1 GNB4 SPAG9 SLC39A14	1.01e-04	507	77	9	GO:0005774
GeneOntologyCellularComponent	lysosome	GLMP DPP4 CYBRD1 MANBA ARSD SLC15A4 HYAL3 TCIRG1 GNB4 SPAG9 SLC39A14	1.81e-04	811	77	11	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	GLMP DPP4 CYBRD1 MANBA ARSD SLC15A4 HYAL3 TCIRG1 GNB4 SPAG9 SLC39A14	1.81e-04	811	77	11	GO:0000323
GeneOntologyCellularComponent	intercellular canaliculus	DPP4 TJP1	4.74e-04	9	77	2	GO:0046581
GeneOntologyCellularComponent	basal part of cell	SLC6A9 FAP TJP1 ENTPD1 ITGA6 ITGA1 SLC39A14	4.85e-04	378	77	7	GO:0045178
GeneOntologyCellularComponent	vacuole	GLMP DPP4 CYBRD1 MANBA ARSD SLC15A4 HYAL3 TCIRG1 GNB4 SPAG9 SLC39A14	4.96e-04	913	77	11	GO:0005773
GeneOntologyCellularComponent	cell body	FEZ1 PTPRN RNF112 IGHMBP2 ENTPD1 GNB4 GRIK4 ITGA1 HCN2 MAP2K1 USH2A	5.74e-04	929	77	11	GO:0044297
GeneOntologyCellularComponent	neuronal cell body	FEZ1 PTPRN RNF112 IGHMBP2 ENTPD1 GRIK4 ITGA1 HCN2 MAP2K1 USH2A	9.54e-04	835	77	10	GO:0043025
GeneOntologyCellularComponent	focal adhesion	DPP4 FAP IGF2R ITGA6 ITGA1 MAP2K1 MAP2K2	1.05e-03	431	77	7	GO:0005925
GeneOntologyCellularComponent	basement membrane	COL4A6 ENTPD1 ITGA6 USH2A	1.08e-03	122	77	4	GO:0005604
GeneOntologyCellularComponent	cell-substrate junction	DPP4 FAP IGF2R ITGA6 ITGA1 MAP2K1 MAP2K2	1.23e-03	443	77	7	GO:0030055
GeneOntologyCellularComponent	secretory granule membrane	IGF2R MANBA SLC15A4 HYAL3 TCIRG1 SYT1	1.35e-03	329	77	6	GO:0030667
GeneOntologyCellularComponent	perikaryon	PTPRN RNF112 GRIK4 ITGA1 MAP2K1	1.40e-03	223	77	5	GO:0043204
GeneOntologyCellularComponent	apical part of cell	SLC6A9 DPP4 FAP CYBRD1 TJP1 TCIRG1 SLC39A14 USH2A	1.49e-03	592	77	8	GO:0045177
GeneOntologyCellularComponent	somatodendritic compartment	PTPN6 FEZ1 PTPRN FAT3 RNF112 IGHMBP2 ENTPD1 GRIK4 ITGA1 HCN2 MAP2K1 USH2A	1.70e-03	1228	77	12	GO:0036477
GeneOntologyCellularComponent	hippocampal mossy fiber to CA3 synapse	SLC6A9 SYT1 GRIK4	1.94e-03	67	77	3	GO:0098686
GeneOntologyCellularComponent	early endosome	IGF2R SLC15A4 HYAL3 GPNMB SLC39A14 MAP2K1 MAP2K2	1.96e-03	481	77	7	GO:0005769
GeneOntologyCellularComponent	protein phosphatase type 2A complex	PPP2R2C PPP2R2D	1.97e-03	18	77	2	GO:0000159
GeneOntologyCellularComponent	apical plasma membrane	SLC6A9 DPP4 CYBRD1 TJP1 TCIRG1 SLC39A14 USH2A	2.11e-03	487	77	7	GO:0016324
GeneOntologyCellularComponent	extracellular matrix	COL4A6 EYS VWF SPON2 ENTPD1 ITGA6 USH2A ANGPTL1	2.82e-03	656	77	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A6 EYS VWF SPON2 ENTPD1 ITGA6 USH2A ANGPTL1	2.88e-03	658	77	8	GO:0030312
GeneOntologyCellularComponent	lamellipodium membrane	DPP4 FAP	2.95e-03	22	77	2	GO:0031258
GeneOntologyCellularComponent	transport vesicle	SLC6A9 IGF2R PTPRN RNF112 ENTPD1 SYT1 SEC23A	3.00e-03	519	77	7	GO:0030133
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A6 EYS VWF ENTPD1 ITGA6 USH2A ANGPTL1	3.37e-03	530	77	7	GO:0062023
GeneOntologyCellularComponent	endosome	SLC6A9 IGF2R PTPRN SLC15A4 HYAL3 RNF112 TCIRG1 GPNMB SLC39A14 MAP2K1 MAP2K2	3.54e-03	1167	77	11	GO:0005768
GeneOntologyCellularComponent	synaptic vesicle	SLC6A9 PTPRN RNF112 ENTPD1 SYT1	5.01e-03	300	77	5	GO:0008021
GeneOntologyCellularComponent	cell projection membrane	DPP4 FAP CYBRD1 PEMT HCN2 USH2A	5.13e-03	431	77	6	GO:0031253
GeneOntologyCellularComponent	distal axon	TSHZ3 FEZ1 PTPRN IGHMBP2 GRIK4 USH2A	5.36e-03	435	77	6	GO:0150034
GeneOntologyCellularComponent	axon	TSHZ3 FEZ1 PTPRN IGHMBP2 SYT1 GRIK4 HCN2 MAP2K1 USH2A	5.37e-03	891	77	9	GO:0030424
Domain	PP2A_PR55	PPP2R2C PPP2R2D	9.75e-05	4	76	2	IPR000009
Domain	PP2A_PR55_CS	PPP2R2C PPP2R2D	9.75e-05	4	76	2	IPR018067
Domain	Pept_S9_AS	DPP4 FAP	9.75e-05	4	76	2	IPR002471
Domain	PR55_2	PPP2R2C PPP2R2D	9.75e-05	4	76	2	PS01025
Domain	PR55_1	PPP2R2C PPP2R2D	9.75e-05	4	76	2	PS01024
Domain	PRO_ENDOPEP_SER	DPP4 FAP	1.62e-04	5	76	2	PS00708
Domain	WD40_repeat_dom	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 SPAG9 HERC1	2.05e-04	297	76	7	IPR017986
Domain	CYTOCHROME_B561	FRRS1 CYBRD1	2.43e-04	6	76	2	PS50939
Domain	B561	FRRS1 CYBRD1	2.43e-04	6	76	2	SM00665
Domain	-	DPP4 FAP	2.43e-04	6	76	2	2.140.10.30
Domain	DPPIV_N	DPP4 FAP	2.43e-04	6	76	2	PF00930
Domain	Cyt_b561/ferric_Rdtase_TM	FRRS1 CYBRD1	2.43e-04	6	76	2	IPR006593
Domain	Peptidase_S9B_N	DPP4 FAP	2.43e-04	6	76	2	IPR002469
Domain	ConA-like_dom	EYS FAT3 NBEA HERC1 CMYA5 USH2A	2.68e-04	219	76	6	IPR013320
Domain	-	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 SPAG9 HERC1	4.10e-04	333	76	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 SPAG9 HERC1	4.25e-04	335	76	7	IPR015943
Domain	LAM_G_DOMAIN	EYS FAT3 USH2A	4.93e-04	38	76	3	PS50025
Domain	Laminin_G_2	EYS FAT3 USH2A	5.74e-04	40	76	3	PF02210
Domain	-	EYS FAT3 NBEA USH2A	6.09e-04	95	76	4	2.60.120.200
Domain	WD40	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	6.52e-04	259	76	6	PF00400
Domain	VWF_A	VWF ANAPC1 ITGA1 SEC23A	7.11e-04	99	76	4	IPR002035
Domain	LamG	EYS FAT3 USH2A	7.61e-04	44	76	3	SM00282
Domain	WD40	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	7.79e-04	268	76	6	SM00320
Domain	WD40_repeat	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	8.41e-04	272	76	6	IPR001680
Domain	Peptidase_S9	DPP4 FAP	8.78e-04	11	76	2	PF00326
Domain	Peptidase_S9	DPP4 FAP	8.78e-04	11	76	2	IPR001375
Domain	WD_REPEATS_1	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	9.42e-04	278	76	6	PS00678
Domain	WD_REPEATS_2	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	9.59e-04	279	76	6	PS50082
Domain	WD_REPEATS_REGION	ZNF106 PPP2R2C PPP2R2D NBEA GNB4 HERC1	9.59e-04	279	76	6	PS50294
Domain	Laminin_G	EYS FAT3 USH2A	1.70e-03	58	76	3	IPR001791
Domain	Integrin_alpha_C_CS	ITGA6 ITGA1	1.89e-03	16	76	2	IPR018184
Domain	Integrin_alpha-2	ITGA6 ITGA1	2.40e-03	18	76	2	IPR013649
Domain	Integrin_alpha2	ITGA6 ITGA1	2.40e-03	18	76	2	PF08441
Domain	Integrin_alpha	ITGA6 ITGA1	2.40e-03	18	76	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGA6 ITGA1	2.40e-03	18	76	2	PS00242
Domain	Int_alpha_beta-p	ITGA6 ITGA1	2.67e-03	19	76	2	IPR013519
Domain	Int_alpha	ITGA6 ITGA1	2.67e-03	19	76	2	SM00191
Domain	FG_GAP	ITGA6 ITGA1	3.58e-03	22	76	2	PS51470
Domain	EGF_1	EYS ADAM20 FAT3 HYAL3 USH2A	3.83e-03	255	76	5	PS00022
Domain	FG-GAP	ITGA6 ITGA1	4.26e-03	24	76	2	PF01839
Domain	FG-GAP	ITGA6 ITGA1	4.26e-03	24	76	2	IPR013517
Domain	Integrin_dom	ITGA6 ITGA1	4.61e-03	25	76	2	IPR032695
Pathway	WP_PI3KAKT_SIGNALING	COL4A6 PPP2R2C VWF PPP2R2D ITGA6 GNB4 ITGA1 MAP2K1 MAP2K2	1.21e-05	339	60	9	M39736
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING	COL4A6 PPP2R2C VWF PPP2R2D ITGA6 GNB4 MAP2K1 MAP2K2	3.93e-05	302	60	8	M39719
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY	COL4A6 PPP2R2C VWF PPP2R2D ITGA6 GNB4 MAP2K1 MAP2K2	6.74e-05	326	60	8	MM15917
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_BRAF_TO_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.77e-04	5	60	2	M49016
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 MAP2K1 MAP2K2	1.99e-04	27	60	3	M47454
Pathway	WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING	ITGA1 MAP2K1 MAP2K2	2.23e-04	28	60	3	M39572
Pathway	REACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS	SYT1 MAP2K1 MAP2K2	2.48e-04	29	60	3	M27431
Pathway	REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY	MAP2K1 MAP2K2	2.64e-04	6	60	2	M27559
Pathway	REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY	MAP2K1 MAP2K2	2.64e-04	6	60	2	MM15273
Pathway	KEGG_MEDICUS_PATHOGEN_YERSINIA_YOPP_J_TO_TLR2_4_MAPK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.64e-04	6	60	2	M47636
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A6 ITGA6 ITGA1	2.74e-04	30	60	3	M27216
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A6 VWF ITGA6 ITGA1	3.03e-04	76	60	4	MM14867
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 MAP2K1 MAP2K2	3.03e-04	31	60	3	M47459
Pathway	BIOCARTA_INTEGRIN_PATHWAY	ITGA1 MAP2K1 MAP2K2	3.65e-04	33	60	3	MM1426
Pathway	BIOCARTA_MET_PATHWAY	ITGA1 MAP2K1 MAP2K2	3.65e-04	33	60	3	MM1494
Pathway	REACTOME_DEFECTIVE_FACTOR_VIII_CAUSES_HEMOPHILIA_A	VWF F8	3.69e-04	7	60	2	M39000
Pathway	WP_HEPATOCYTE_GROWTH_FACTOR_RECEPTOR_SIGNALING	ITGA1 MAP2K1 MAP2K2	3.99e-04	34	60	3	M39383
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL4A6 VWF ITGA6 ITGA1	4.44e-04	84	60	4	M7098
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A6 VWF ITGA6 ITGA1	4.64e-04	85	60	4	M16441
Pathway	REACTOME_MAP2K_AND_MAPK_ACTIVATION	VWF MAP2K1 MAP2K2	6.01e-04	39	60	3	MM15272
Pathway	WP_ETHANOL_METABOLISM_PRODUCTION_OF_ROS_BY_CYP2E1	MAP2K1 MAP2K2	6.29e-04	9	60	2	M39481
Pathway	REACTOME_MAP2K_AND_MAPK_ACTIVATION	VWF MAP2K1 MAP2K2	6.47e-04	40	60	3	M27557
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	7.84e-04	10	60	2	M47374
Pathway	KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	7.84e-04	10	60	2	M47420
Pathway	WP_ETHANOL_METABOLISM_RESULTING_IN_PRODUCTION_OF_ROS_BY_CYP2E1	MAP2K1 MAP2K2	7.84e-04	10	60	2	MM15821
Pathway	KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	7.84e-04	10	60	2	M47735
Pathway	REACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS	VWF MAP2K1 MAP2K2	9.16e-04	45	60	3	M27623
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA6 ITGA1 MAP2K1 MAP2K2	9.23e-04	102	60	4	M39577
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA6 ITGA1 MAP2K1 MAP2K2	9.23e-04	102	60	4	MM15830
Pathway	KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	9.56e-04	11	60	2	M47370
Pathway	KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	9.56e-04	11	60	2	M47371
Pathway	REACTOME_UPTAKE_AND_FUNCTION_OF_ANTHRAX_TOXINS	MAP2K1 MAP2K2	9.56e-04	11	60	2	M27420
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.14e-03	12	60	2	M47369
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.14e-03	12	60	2	M47597
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.14e-03	12	60	2	M47815
Pathway	PID_ARF6_TRAFFICKING_PATHWAY	ITGA6 SPAG9 ITGA1	1.18e-03	49	60	3	M67
Pathway	WP_FOCAL_ADHESION	COL4A6 VWF ITGA6 MAP2K1 MAP2K2	1.18e-03	187	60	5	MM15913
Pathway	KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.35e-03	13	60	2	M47589
Pathway	BIOCARTA_CDK5_PATHWAY	MAP2K1 MAP2K2	1.35e-03	13	60	2	M89
Pathway	PID_KIT_PATHWAY	PTPN6 MAP2K1 MAP2K2	1.40e-03	52	60	3	M231
Pathway	WP_FOCAL_ADHESION	COL4A6 VWF ITGA6 ITGA1 MAP2K1	1.55e-03	199	60	5	M39402
Pathway	KEGG_FOCAL_ADHESION	COL4A6 VWF ITGA6 ITGA1 MAP2K1	1.55e-03	199	60	5	M7253
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M668
Pathway	KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47364
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47365
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47366
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47378
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47383
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47384
Pathway	REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS	MAP2K1 MAP2K2	1.57e-03	14	60	2	M622
Pathway	REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS	MAP2K1 MAP2K2	1.57e-03	14	60	2	MM14667
Pathway	BIOCARTA_CDK5_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	MM1457
Pathway	KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	M47488
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	MAP2K1 MAP2K2	1.57e-03	14	60	2	MM1489
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47367
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47375
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47382
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47380
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47592
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47593
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47640
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A6 ITGA6	1.81e-03	15	60	2	MM14922
Pathway	BIOCARTA_IL3_PATHWAY	PTPN6 MAP2K1	1.81e-03	15	60	2	MM1412
Pathway	KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47485
Pathway	KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47473
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47474
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47480
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47495
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47496
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47497
Pathway	BIOCARTA_IL3_PATHWAY	PTPN6 MAP2K1	1.81e-03	15	60	2	M17681
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47472
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47535
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	1.81e-03	15	60	2	M47531
Pathway	WP_KIT_RECEPTOR_SIGNALING	PTPN6 MAP2K1 MAP2K2	2.01e-03	59	60	3	M39350
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47363
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47373
Pathway	KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47381
Pathway	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF ITGA1	2.06e-03	16	60	2	M9450
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47804
Pathway	KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47801
Pathway	REACTOME_DEFECTS_OF_CONTACT_ACTIVATION_SYSTEM_CAS_AND_KALLIKREIN_KININ_SYSTEM_KKS	VWF F8	2.06e-03	16	60	2	M38996
Pathway	WP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER	MAP2K1 MAP2K2	2.06e-03	16	60	2	M39882
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47483
Pathway	KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.06e-03	16	60	2	M47682
Pathway	WP_TCELL_ANTIGEN_RECEPTOR_TCR_PATHWAY_DURING_STAPHYLOCOCCUS_AUREUS_INFECTION	PTPN6 MAP2K1 MAP2K2	2.32e-03	62	60	3	M39429
Pathway	WP_ERK_PATHWAY_IN_HUNTINGTONS_DISEASE	MAP2K1 MAP2K2	2.33e-03	17	60	2	M39564
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	M47376
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 SYT1	2.33e-03	17	60	2	M93
Pathway	BIOCARTA_HCMV_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	M8353
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 SYT1	2.33e-03	17	60	2	MM14907
Pathway	BIOCARTA_HCMV_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	MM1408
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	M111
Pathway	WP_IL9_SIGNALING	MAP2K1 MAP2K2	2.33e-03	17	60	2	M39644
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	M47684
Pathway	SA_TRKA_RECEPTOR	MAP2K1 MAP2K2	2.33e-03	17	60	2	M18895
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	MAP2K1 MAP2K2	2.33e-03	17	60	2	MM1491
Pathway	PID_ANTHRAX_PATHWAY	MAP2K1 MAP2K2	2.61e-03	18	60	2	M267
Pathway	BIOCARTA_MAL_PATHWAY	MAP2K1 MAP2K2	2.61e-03	18	60	2	MM1482
Pathway	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 SYT1	2.61e-03	18	60	2	M13015
Pubmed	Collagen type IV, laminin, alpha-smooth muscle actin (alphaSMA), alpha1 and alpha6 integrins expression in the liver with metastases from malignant gastrointestinal tumours.	COL4A6 ITGA6 ITGA1	4.33e-08	4	78	3	15679046
Pubmed	MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade.	PITRM1 MAP2K1 MAP2K2	1.08e-07	5	78	3	9733512
Pubmed	Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.	TJP1 ITGA6 ITGA1 SLC39A14	2.97e-06	44	78	4	30024968
Pubmed	Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets.	DPP4 FAP	4.97e-06	2	78	2	25361590
Pubmed	Intracellular interaction of von Willebrand factor and factor VIII depends on cellular context: lessons from platelet-expressed factor VIII.	VWF F8	4.97e-06	2	78	2	15731176
Pubmed	Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.	DPP4 FAP	4.97e-06	2	78	2	20155839
Pubmed	Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor.	MAP2K1 MAP2K2	4.97e-06	2	78	2	9563949
Pubmed	A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.	VWF F8	4.97e-06	2	78	2	38320121
Pubmed	Rise of levels of von Willebrand factor and factor VIII with age: Role of genetic and acquired risk factors.	VWF F8	4.97e-06	2	78	2	33221577
Pubmed	Mechano-covalent protection of coagulation factor VIII by von Willebrand factor.	VWF F8	4.97e-06	2	78	2	36240294
Pubmed	Inflammation, hemostasis, and the risk of kidney function decline in the Atherosclerosis Risk in Communities (ARIC) Study.	VWF F8	4.97e-06	2	78	2	19110358
Pubmed	Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.	VWF F8	4.97e-06	2	78	2	23690449
Pubmed	Mek2 is dispensable for mouse growth and development.	MAP2K1 MAP2K2	4.97e-06	2	78	2	12832465
Pubmed	Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.	VWF F8	4.97e-06	2	78	2	22219226
Pubmed	Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.	MAP2K1 MAP2K2	4.97e-06	2	78	2	19014680
Pubmed	von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.	VWF F8	4.97e-06	2	78	2	26635035
Pubmed	Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression.	DPP4 PEMT	4.97e-06	2	78	2	36472923
Pubmed	The role of VWF in the immunogenicity of FVIII.	VWF F8	4.97e-06	2	78	2	18549909
Pubmed	Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas.	DPP4 FAP	4.97e-06	2	78	2	28452380
Pubmed	The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor.	VWF F8	4.97e-06	2	78	2	9218428
Pubmed	The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor.	VWF F8	4.97e-06	2	78	2	7756647
Pubmed	Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.	DPP4 FAP	4.97e-06	2	78	2	7911242
Pubmed	Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort.	VWF F8	4.97e-06	2	78	2	18535282
Pubmed	Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus.	VWF F8	4.97e-06	2	78	2	20624989
Pubmed	Association of the factor VIII light chain with von Willebrand factor.	VWF F8	4.97e-06	2	78	2	3134349
Pubmed	The influence of von Willebrand factor on factor VIII activity measurements.	VWF F8	4.97e-06	2	78	2	18983499
Pubmed	Factor VIII and von Willebrand factor changes during normal pregnancy and puerperium.	VWF F8	4.97e-06	2	78	2	14517489
Pubmed	Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells.	MAP2K1 MAP2K2	4.97e-06	2	78	2	26625317
Pubmed	Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities.	VWF F8	4.97e-06	2	78	2	15471879
Pubmed	The defective interaction between von Willebrand factor and factor VIII in a patient with type 1 von Willebrand disease is caused by substitution of Arg19 and His54 in mature von Willebrand factor.	VWF F8	4.97e-06	2	78	2	8562925
Pubmed	Targeted disruption of mouse fibroblast activation protein.	DPP4 FAP	4.97e-06	2	78	2	10629066
Pubmed	von Willebrand factor variant p.Arg924Gln marks an allele associated with reduced von Willebrand factor and factor VIII levels.	VWF F8	4.97e-06	2	78	2	20492463
Pubmed	Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours.	DPP4 FAP	4.97e-06	2	78	2	19817894
Pubmed	Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation.	MAP2K1 MAP2K2	4.97e-06	2	78	2	21699731
Pubmed	Solution structure of the major factor VIII binding region on von Willebrand factor.	VWF F8	4.97e-06	2	78	2	24700780
Pubmed	Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia.	MAP2K1 MAP2K2	4.97e-06	2	78	2	17419998
Pubmed	Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.	VWF F8	4.97e-06	2	78	2	21940821
Pubmed	Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings.	VWF F8	4.97e-06	2	78	2	26473492
Pubmed	MEK1 and MEK2 differentially control the duration and amplitude of the ERK cascade response.	MAP2K1 MAP2K2	4.97e-06	2	78	2	23735655
Pubmed	The Predictive Value of MAP2K1/2 Mutations on Efficiency of Immunotherapy in Melanoma.	MAP2K1 MAP2K2	4.97e-06	2	78	2	35069558
Pubmed	Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment.	VWF F8	4.97e-06	2	78	2	20194895
Pubmed	VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.	VWF F8	4.97e-06	2	78	2	23349392
Pubmed	Interaction between VWF and FVIII in treating VWD.	VWF F8	4.97e-06	2	78	2	25605439
Pubmed	The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.	MAP2K1 MAP2K2	4.97e-06	2	78	2	21527500
Pubmed	Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.	MAP2K1 MAP2K2	4.97e-06	2	78	2	19383924
Pubmed	von Willebrand factor modulates immune complexes and the recall response against factor VIII in a murine hemophilia A model.	VWF F8	4.97e-06	2	78	2	37756521
Pubmed	MEK1 and MEK2, different regulators of the G1/S transition.	MAP2K1 MAP2K2	4.97e-06	2	78	2	15284233
Pubmed	Coupled expression of dipeptidyl peptidase-IV and fibroblast activation protein-α in transformed astrocytic cells.	DPP4 FAP	4.97e-06	2	78	2	21526345
Pubmed	Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype-phenotype correlations.	MAP2K1 MAP2K2	4.97e-06	2	78	2	19156172
Pubmed	Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling.	DPP4 FAP	4.97e-06	2	78	2	25816202
Pubmed	p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2.	MAP2K1 MAP2K2	4.97e-06	2	78	2	12839928
Pubmed	MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.	MAP2K1 MAP2K2	4.97e-06	2	78	2	16957420
Pubmed	Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.	VWF F8	4.97e-06	2	78	2	17958741
Pubmed	Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis.	DPP4 FAP	4.97e-06	2	78	2	27990763
Pubmed	Von Willebrand factor processing.	VWF F8	4.97e-06	2	78	2	28139814
Pubmed	T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate.	MAP2K1 MAP2K2	4.97e-06	2	78	2	19144315
Pubmed	Von Willebrand and Factor VIII Portosystemic Circulation Gradient in Cirrhosis: Implications for Portal Vein Thrombosis.	VWF F8	4.97e-06	2	78	2	32032127
Pubmed	Anti-heavy-chain monoclonal antibodies directed to the acidic regions of the factor VIII molecule inhibit the binding of factor VIII to phospholipids and von Willebrand factor.	VWF F8	4.97e-06	2	78	2	12958606
Pubmed	Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition.	MAP2K1 MAP2K2	4.97e-06	2	78	2	19500021
Pubmed	Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.	MAP2K1 MAP2K2	4.97e-06	2	78	2	22197931
Pubmed	Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.	VWF F8	4.97e-06	2	78	2	37720212
Pubmed	Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.	VWF F8	4.97e-06	2	78	2	23168412
Pubmed	Physiological Roles of the von Willebrand Factor-Factor VIII Interaction.	VWF F8	4.97e-06	2	78	2	32189311
Pubmed	Factor VIII binding affects the mechanical unraveling of the A2 domain of von Willebrand factor.	VWF F8	4.97e-06	2	78	2	32544272
Pubmed	Allosteric MEK1/2 inhibitors including cobimetanib and trametinib in the treatment of cutaneous melanomas.	MAP2K1 MAP2K2	4.97e-06	2	78	2	27956260
Pubmed	Von Willebrand factor accelerates platelet adhesion and thrombus formation on a collagen surface in platelet-reduced blood under flow conditions.	VWF F8	4.97e-06	2	78	2	15459008
Pubmed	Germline mutations of MEK in cardio-facio-cutaneous syndrome are sensitive to MEK and RAF inhibition: implications for therapeutic options.	MAP2K1 MAP2K2	4.97e-06	2	78	2	17981815
Pubmed	A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.	VWF F8	4.97e-06	2	78	2	23335368
Pubmed	Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.	MAP2K1 MAP2K2	4.97e-06	2	78	2	28746311
Pubmed	High levels of coagulation factors and venous thrombosis risk: strongest association for factor VIII and von Willebrand factor.	VWF F8	4.97e-06	2	78	2	30471183
Pubmed	Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding.	VWF F8	4.97e-06	2	78	2	12719775
Pubmed	Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases.	MAP2K1 MAP2K2	4.97e-06	2	78	2	30087384
Pubmed	The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.	VWF F8	4.97e-06	2	78	2	30642920
Pubmed	Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.	VWF F8	4.97e-06	2	78	2	16823491
Pubmed	The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.	VWF F8	4.97e-06	2	78	2	30111575
Pubmed	Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.	MAP2K1 MAP2K2	4.97e-06	2	78	2	22833572
Pubmed	Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells.	VWF F8	4.97e-06	2	78	2	35950488
Pubmed	Coagulation factor VIII regulates von Willebrand factor homeostasis invivo.	VWF F8	4.97e-06	2	78	2	37726033
Pubmed	Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex.	DPP4 FAP	4.97e-06	2	78	2	12023964
Pubmed	A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.	VWF F8	4.97e-06	2	78	2	22855607
Pubmed	Sources of variation in factor VIII, von Willebrand factor and fibrinogen measurements: implications for detecting deficiencies and increased plasma levels.	VWF F8	4.97e-06	2	78	2	20627205
Pubmed	Evaluation of von Willebrand factor phenotypes and genotypes in Hemophilia A patients with and without identified F8 mutations.	VWF F8	4.97e-06	2	78	2	25780857
Pubmed	ERK1/2 can feedback-regulate cellular MEK1/2 levels.	MAP2K1 MAP2K2	4.97e-06	2	78	2	26163823
Pubmed	Plasma seprase and DPP4 levels as markers of disease and prognosis in cancer.	DPP4 FAP	4.97e-06	2	78	2	22674411
Pubmed	Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism.	MAP2K1 MAP2K2	4.97e-06	2	78	2	36189831
Pubmed	Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.	MAP2K1 MAP2K2	4.97e-06	2	78	2	22805292
Pubmed	Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial.	MAP2K1 MAP2K2	4.97e-06	2	78	2	22805291
Pubmed	Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans.	VWF F8	4.97e-06	2	78	2	25779970
Pubmed	Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A.	VWF F8	4.97e-06	2	78	2	27749002
Pubmed	von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins.	VWF F8	4.97e-06	2	78	2	17119108
Pubmed	Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway.	MAP2K1 MAP2K2	4.97e-06	2	78	2	35975983
Pubmed	Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts.	DPP4 FAP	4.97e-06	2	78	2	10593948
Pubmed	Correlation between von Willebrand factor antigen, von Willebrand factor ristocetin cofactor activity and factor VIII activity in plasma.	VWF F8	4.97e-06	2	78	2	17786534
Pubmed	Inhibitors of the mitogen-activated protein kinase kinase 1/2 signaling pathway clear prion-infected cells from PrPSc.	MAP2K1 MAP2K2	4.97e-06	2	78	2	16162927
Pubmed	Regulation of intracellular MEK1/2 translocation in mouse oocytes: cytoplasmic dynein/dynactin-mediated poleward transport and cyclin B degradation-dependent release from spindle poles.	MAP2K1 MAP2K2	4.97e-06	2	78	2	17507801
Pubmed	Abnormal von Willebrand factor secretion, factor VIII stabilization and thrombus dynamics in type 2N von Willebrand disease mice.	VWF F8	4.97e-06	2	78	2	28581694
Pubmed	Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.	VWF F8	4.97e-06	2	78	2	27207787
Pubmed	High factor VIII antigen levels increase the risk of venous thrombosis but are not associated with polymorphisms in the von Willebrand factor and factor VIII gene.	VWF F8	4.97e-06	2	78	2	11722428
Pubmed	Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells.	VWF F8	4.97e-06	2	78	2	16953272
Pubmed	Type 2N von Willebrand disease due to compound heterozygosity for R854Q and a novel R763G mutation at the cleavage site of von Willebrand factor propeptide.	VWF F8	4.97e-06	2	78	2	16953269
GeneFamily	Mitogen-activated protein kinase kinases	MAP2K1 MAP2K2	1.75e-04	7	53	2	653
GeneFamily	CD molecules\|DASH family	DPP4 FAP	1.75e-04	7	53	2	1205
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R2C PPP2R2D	8.64e-04	15	53	2	696
GeneFamily	WD repeat domain containing	PPP2R2C PPP2R2D NBEA GNB4 HERC1	1.00e-03	262	53	5	362
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA6 ITGA1	1.25e-03	18	53	2	1160
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	NBEA CMYA5	3.25e-03	29	53	2	396
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	DPP4 IGF2R ENTPD1 ITGA6 ITGA1	5.83e-03	394	53	5	471
GeneFamily	Solute carriers	SLC6A9 SLC15A4 SLC19A3 SLC25A53 SLC39A14	5.89e-03	395	53	5	752
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_1000	COL4A6 DPP4 CYBRD1 FEZ1 FAT3 ENTPD1 GNB4 ANGPTL1	1.52e-06	230	75	8	gudmap_developingGonad_P2_epididymis_1000_k2
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500	FAP ANAPC1 ENTPD1 GNB4 MN1 ANGPTL1	1.11e-05	142	75	6	gudmap_developingKidney_e13.5_podocyte cells_500_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#1_top-relative-expression-ranked_1000	FAP SYT1 GNB4 MN1 ANGPTL1	5.01e-05	113	75	5	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k1
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS FAT3 SYT1 GRIK4 CSMD2 USH2A	3.69e-07	159	78	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A9 CYBRD1 SPON2 GNB4 ITGA1 HCN2	6.05e-07	173	78	6	f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A9 CYBRD1 SPON2 GNB4 ITGA1 HCN2	6.05e-07	173	78	6	cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	VWF INPP1 ENTPD1 HIPK2 ITGA1 F8	1.15e-06	193	78	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	VWF INPP1 ENTPD1 HIPK2 ITGA1 F8	1.15e-06	193	78	6	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	ASK440-Endothelial-Endothelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	VWF TJP1 ITGA6 SYT1 ITGA1 F8	1.22e-06	195	78	6	304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell	390C-Lymphocytic-NK_cells\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PTPN6 IGF2R FEZ1 SLC15A4 SPON2 HIPK2	1.33e-06	198	78	6	623e5ada1a54cd42c32a1519b84dbe782384ee0c
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SOX2 FAP MANBA HERC1 CMYA5	1.30e-05	172	78	5	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SOX2 FAP MANBA HERC1 CMYA5	1.30e-05	172	78	5	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	PTPRN RNF112 SYT1 TEX15 HERC1	1.45e-05	176	78	5	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A9 CYBRD1 GNB4 ITGA1 HCN2	1.45e-05	176	78	5	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A9 CYBRD1 GNB4 ITGA1 HCN2	1.45e-05	176	78	5	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP SPON2 GPNMB MN1 ANGPTL1	1.89e-05	186	78	5	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	DPP4 FEZ1 SPON2 GPNMB ANGPTL1	1.99e-05	188	78	5	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	Pericytes-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	COL4A6 FAT3 ITGA1 CSMD2 ANGPTL1	1.99e-05	188	78	5	14c1c88a944c66f2eaac1ce7526815dcce1f5147
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	VWF ENTPD1 HIPK2 ITGA1 F8	2.04e-05	189	78	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	VWF ENTPD1 HIPK2 ITGA1 F8	2.04e-05	189	78	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A6 SPON2 SYT1 GRIK4 TEX15	2.10e-05	190	78	5	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	VWF HIPK2 ITGA6 ITGA1 F8	2.10e-05	190	78	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A6 SPON2 SYT1 GRIK4 TEX15	2.10e-05	190	78	5	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF TJP1 HIPK2 ITGA1 F8	2.15e-05	191	78	5	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	IPF-Lymphoid-NK\|Lymphoid / Disease state, Lineage and Cell class	IGF2R SLC15A4 SPON2 HIPK2 GRIK4	2.15e-05	191	78	5	f2ddc0962007d7a4e78fbd916ebb62fc557d480a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ZNF106 FAP FAT3 GRIK4 ITGA1	2.20e-05	192	78	5	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	FAP TSHZ3 FAT3 GRIK4 ITGA1	2.26e-05	193	78	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAP TSHZ3 FAT3 GRIK4 ITGA1	2.32e-05	194	78	5	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A6 SPON2 SYT1 GRIK4 TEX15	2.37e-05	195	78	5	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A6 SPON2 SYT1 GRIK4 TEX15	2.37e-05	195	78	5	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF ENTPD1 ITGA6 ITGA1 F8	2.49e-05	197	78	5	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	COVID-19_Severe-NK\|COVID-19_Severe / Disease condition and Cell class	IGF2R FEZ1 SLC15A4 SPON2 HIPK2	2.55e-05	198	78	5	742c4d6016cfa48444a5919a885ab8d02cad7e18
ToppCell	mild-Lymphocytic-NK_cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IGF2R SLC15A4 SPON2 HIPK2 GRIK4	2.55e-05	198	78	5	1d20fc9948965de52a98f758035edfdd12cafc5f
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF TJP1 ITGA6 ITGA1 F8	2.55e-05	198	78	5	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	FEZ1 FAT3 NBEA CSMD2 MN1	2.55e-05	198	78	5	60d8d3bbd754ffde41c50013d822667b185a9751
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC6A9 EYS HYAL3 CYP4F22 HCN2	2.61e-05	199	78	5	565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCell	Control-NK\|Control / Disease condition and Cell class	IGF2R FEZ1 SLC15A4 SPON2 HIPK2	2.61e-05	199	78	5	f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	COL4A6 CS FAM120A HIPK2 MN1	2.61e-05	199	78	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PTPN6 ENTPD1 ITGA6 TCIRG1 ITGA1	2.68e-05	200	78	5	0eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PTPN6 ENTPD1 ITGA6 TCIRG1 ITGA1	2.68e-05	200	78	5	01d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF106 VWF ITGA6 SYT1 F8	2.68e-05	200	78	5	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PTPN6 FEZ1 SLC15A4 SPON2 HIPK2	2.68e-05	200	78	5	48ca9269ee3962d13408fef12b5be120759eac52
ToppCell	proximal-Endothelial-Bronchial_Vessel_1\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF INPP1 ENTPD1 ITGA6 F8	2.68e-05	200	78	5	d034bd210c87b704acf45f50d888497c8737011b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	HIPK3 COL4A6 TSHZ3 FAM120A MAP2K1	2.68e-05	200	78	5	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	COVID-19_Mild-NK\|COVID-19_Mild / Disease condition and Cell class	IGF2R FEZ1 SLC15A4 SPON2 HIPK2	2.68e-05	200	78	5	b586b0f1127293c2f8529be16b24229359041da2
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYBRD1 FEZ1 GPNMB SLC39A14 ANGPTL1	2.68e-05	200	78	5	74ad0ae592252060ee294d7483327d765a6ba1dd
ToppCell	proximal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF INPP1 ENTPD1 ITGA6 F8	2.68e-05	200	78	5	0ff4185021ec84b57be13b28495e2f8a4d195eb6
ToppCell	proximal-Endothelial-Bronchial_Vessel_1-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF INPP1 ENTPD1 ITGA6 F8	2.68e-05	200	78	5	e4f6e0b9502eb531f28d605f9dbda6a72a9ed320
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PHKA1 CRYGD FAM186A TEX15	9.85e-05	137	78	4	0bb5cccc31e7c44d44a2db3f59b68f9a81503151
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP4 EYS CYP4F22 MN1	1.04e-04	139	78	4	d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS SYT1 CSMD2 USH2A	1.33e-04	148	78	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IGF2R FEZ1 INPP1 SPON2	1.43e-04	151	78	4	0cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IGF2R FEZ1 INPP1 SPON2	1.43e-04	151	78	4	b545823113a3450c5f841f7de48bf0937593544f
ToppCell	Basal_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	SOX2 COL4A6 SYT1 CMYA5	1.59e-04	155	78	4	30accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CAPN14 TSHZ3 SPON2 HIPK2	1.62e-04	156	78	4	e6798d2b9c2c1fc6525c24f596f25aa85a375651
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FAT3 HIPK2 SYT1 CMYA5	1.67e-04	157	78	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CAPN14 PPP2R2C PPFIA4 ITGA1	1.71e-04	158	78	4	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FEZ1 SLC15A4 SPON2 RNF112	1.71e-04	158	78	4	1bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SOX2 COL4A6 CAPN14 ENTPD1	1.75e-04	159	78	4	ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SOX2 COL4A6 CAPN14 ENTPD1	1.75e-04	159	78	4	b05fda31b77536a1878f55d3199563b53f9420b2
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS CYP4F22 GRIK4 USH2A	1.92e-04	163	78	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	normal_Pleural_Fluid-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	FRRS1 FEZ1 GPNMB HCN2	2.06e-04	166	78	4	d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAP CYBRD1 PTPRN RNF112	2.11e-04	167	78	4	743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAP CYBRD1 PTPRN RNF112	2.11e-04	167	78	4	1adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAP IGF2R ITGA1 MAP2K1	2.11e-04	167	78	4	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 TJP1 PPFIA4 CMYA5	2.16e-04	168	78	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 IGF2R VWF ENTPD1	2.16e-04	168	78	4	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 VWF ADAM20 ITGA1	2.16e-04	168	78	4	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 IGF2R VWF ENTPD1	2.16e-04	168	78	4	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRRS1 FEZ1 SPON2 ITGA1	2.21e-04	169	78	4	225aec04ba762d4c55885257de03a65b63503fbb
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRRS1 FEZ1 SPON2 ITGA1	2.21e-04	169	78	4	278960f940b646a788360b1c84d641a8d169896b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP PTPRN SYT1 ITGA1	2.21e-04	169	78	4	6ff1172da690ca17f7108f1617b255b766971a57
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SOX2 TSHZ3 FEZ1 NBEA	2.26e-04	170	78	4	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SOX2 PTPRN NR0B1 SYT1	2.26e-04	170	78	4	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN6 SLC19A3 CMYA5 MN1	2.26e-04	170	78	4	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	A3GALT2 GPNMB ANGPTL1	2.32e-04	68	78	3	9ce22a6dea3c17d5352572ea0dabe6c6120b9f82
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	A3GALT2 GPNMB ANGPTL1	2.32e-04	68	78	3	89d337147899a978a7467db24e876a613bdd2288
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	IGF2R FEZ1 SLC15A4 GRIK4	2.36e-04	172	78	4	701de463f85aaad3a4b36a0d5fbc416406620089
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX2 FEZ1 PTPRN SYT1	2.47e-04	174	78	4	742c73c9e090848b464323cb17579b86658c6792
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-E\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	VWF HIPK2 ITGA6 ITGA1	2.47e-04	174	78	4	4a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRN A3GALT2 ITGA6 ANGPTL1	2.47e-04	174	78	4	a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX2 FEZ1 PTPRN SYT1	2.47e-04	174	78	4	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 IGF2R VWF ENTPD1	2.47e-04	174	78	4	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRN A3GALT2 ITGA6 ANGPTL1	2.47e-04	174	78	4	6cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRN A3GALT2 ITGA6 ANGPTL1	2.47e-04	174	78	4	4b8bc5568e36031c8ecf001bb646809038c23919
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 IGF2R VWF ENTPD1	2.47e-04	174	78	4	f04edf2ca6788875c9918611e416fb739924382e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRN SYT1 CSMD2 HCN2	2.52e-04	175	78	4	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRN SYT1 CSMD2 HCN2	2.52e-04	175	78	4	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHKA1 PTPN6 FRRS1 GRIK4	2.52e-04	175	78	4	f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAP VWF ITGA6 ITGA1	2.63e-04	177	78	4	fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SLC6A9 FEZ1 PTPRN GPNMB	2.63e-04	177	78	4	b647667da62a91dbe3890820142626e26aa779d2
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAP VWF ITGA6 ITGA1	2.63e-04	177	78	4	12f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	VWF PTPRN ITGA6 F8	2.63e-04	177	78	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	HIPK2 SPAG9 GRIK4 HERC1	2.63e-04	177	78	4	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN6 SLC19A3 TCIRG1 GPNMB	2.69e-04	178	78	4	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYBRD1 GPNMB CMYA5 ANGPTL1	2.75e-04	179	78	4	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSHZ3 VWF SLC39A14 F8	2.75e-04	179	78	4	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP2R2C VWF ITGA6 NBEA	2.81e-04	180	78	4	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAP TSHZ3 SYT1 ITGA1	2.81e-04	180	78	4	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN6 FRRS1 TCIRG1 GPNMB	2.81e-04	180	78	4	cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAP TSHZ3 SYT1 ITGA1	2.81e-04	180	78	4	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP2R2C VWF ITGA6 NBEA	2.81e-04	180	78	4	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EYS VWF ENTPD1 TCIRG1	2.81e-04	180	78	4	5861b44acfb8fe92c281c8355bf19c059b3dcd64
Drug	Grgds	SOX2 VWF RNF112 ENTPD1 ITGA6	9.16e-06	83	77	5	CID000123811
Drug	(2s,5s)-5-Carboxymethylproline	SOX2 COL4A6 VWF IGHMBP2 ITGA6 SPAG9 ITGA1 F8	1.10e-05	314	77	8	CID000447989
Drug	TAK 733	MAP2K1 MAP2K2	1.13e-05	2	77	2	ctd:C558666
Drug	2i3z	DPP4 FAP	1.13e-05	2	77	2	CID011987865
Drug	Anti-Retroviral Agents	VWF F8	1.13e-05	2	77	2	ctd:D044966
Drug	2gbi	DPP4 FAP	1.13e-05	2	77	2	CID006914643
Drug	N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide	MAP2K1 MAP2K2	1.13e-05	2	77	2	ctd:C544830
Drug	sodium citrate	FRRS1 VWF RBM19 F8	1.48e-05	44	77	4	CID000006224
Drug	AC1L1IHP	PHKA1 PTPN6 PPP2R2C IGF2R PPP2R2D PTPRN TK2 RBM19 SYT1 MAP2K1 MAP2K2	3.24e-05	728	77	11	CID000004584
Drug	Doct-PC	PEMT SPAG9	3.38e-05	3	77	2	CID000620428
Drug	RO5126766	MAP2K1 MAP2K2	3.38e-05	3	77	2	ctd:C577924
Drug	1gaf	PEMT RBM19 IGHMBP2 SPAG9	3.89e-05	56	77	4	CID000444283
Drug	PVLA	ITGA6 ITGA1 MAP2K1	5.47e-05	22	77	3	CID000126094
Drug	Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; PC3; HT_HG-U133A	HIPK3 FEZ1 TK2 IGHMBP2 NR0B1 SLC19A3	5.53e-05	197	77	6	4570_UP
Drug	benserazide hydrochloride; Down 200; 10uM; MCF7; HG-U133A	PTPRN ADAM20 SPON2 SLC19A3 HIPK2 SPAG9	5.85e-05	199	77	6	641_DN
Drug	glycylproline 4-nitroanilide	DPP4 FAP	6.74e-05	4	77	2	ctd:C042892
Drug	benzyl methacrylate	NR0B1 F8	6.74e-05	4	77	2	CID000017236
Drug	dihydroxy(oxo)azanium	MANBA TJP1 TK2	7.15e-05	24	77	3	CID000498506
Drug	AC1L71LN	MANBA PTPRN TK2 RBM19 HIPK2	7.42e-05	128	77	5	CID000327966
Disease	von Willebrand's disease 2 (is_marker_for)	VWF F8	6.37e-06	2	75	2	DOID:0060574 (is_marker_for)
Disease	small intestine adenocarcinoma (is_implicated_in)	MAP2K1 MAP2K2	1.91e-05	3	75	2	DOID:4906 (is_implicated_in)
Disease	lifestyle measurement, alcohol consumption measurement	PPP2R2C VWF SPON2 CSMD2	2.15e-04	115	75	4	EFO_0007878, EFO_0010724
Disease	RASopathy (implicated_via_orthology)	MAP2K1 MAP2K2	2.27e-04	9	75	2	DOID:0080690 (implicated_via_orthology)
Disease	lymphocyte measurement	MANBA FEZ1 ANAPC1 ITGA1	2.30e-04	117	75	4	EFO_0803546
Disease	Turner Syndrome, Male	MAP2K1 MAP2K2	3.45e-04	11	75	2	C0041409
Disease	Female Pseudo-Turner Syndrome	MAP2K1 MAP2K2	3.45e-04	11	75	2	C1527404
Disease	Noonan Syndrome 1	MAP2K1 MAP2K2	3.45e-04	11	75	2	C4551602
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	PPP2R2C PPP2R2D	4.14e-04	12	75	2	DOID:1441 (implicated_via_orthology)
Disease	hypothyroidism (implicated_via_orthology)	PHKA1 CS	4.88e-04	13	75	2	DOID:1459 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	SLC6A9 DPP4 TSHZ3 MANBA PPP2R2D SYT1	5.33e-04	398	75	6	EFO_0003756, EFO_0003888, EFO_0004337
Disease	Paroxysmal atrial fibrillation	VWF PPFIA4 GNB4 HERC1	6.83e-04	156	75	4	C0235480
Disease	familial atrial fibrillation	VWF PPFIA4 GNB4 HERC1	6.83e-04	156	75	4	C3468561
Disease	Persistent atrial fibrillation	VWF PPFIA4 GNB4 HERC1	6.83e-04	156	75	4	C2585653
Disease	Atrial Fibrillation	VWF PPFIA4 GNB4 HERC1	7.50e-04	160	75	4	C0004238
Disease	Noonan-Like Syndrome With Loose Anagen Hair	MAP2K1 MAP2K2	1.06e-03	19	75	2	C3501846
Disease	Costello syndrome (disorder)	MAP2K1 MAP2K2	1.06e-03	19	75	2	C0587248
Disease	Noonan syndrome-like disorder with loose anagen hair	MAP2K1 MAP2K2	1.06e-03	19	75	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	MAP2K1 MAP2K2	1.06e-03	19	75	2	C1275081
Disease	response to selective serotonin reuptake inhibitor	TSHZ3 CSMD2 MAP2K1	1.21e-03	82	75	3	EFO_0005658
Disease	breast cancer (is_marker_for)	SOX2 ITGA1 MAP2K1 MAP2K2	1.28e-03	185	75	4	DOID:1612 (is_marker_for)
Disease	LEOPARD Syndrome	MAP2K1 MAP2K2	1.42e-03	22	75	2	C0175704
Disease	Respiratory Hypersensitivity	PTPN6 SLC39A14	1.42e-03	22	75	2	C0035228
Disease	peripheral arterial disease, traffic air pollution measurement	TSHZ3 PPP2R2C FEZ1 NBEA	1.53e-03	194	75	4	EFO_0004265, EFO_0007908
Disease	Noonan Syndrome	MAP2K1 MAP2K2	1.70e-03	24	75	2	C0028326
Disease	Schizophrenia	SLC6A9 PTPN6 PEMT ZNF530 FEZ1 GRIK4 CMYA5 CSMD2	1.79e-03	883	75	8	C0036341
Disease	Ataxia	SOX2 PITRM1	1.84e-03	25	75	2	C0004134
Disease	retinal vasculature measurement	SLC6A9 ZNF106 EYS FEZ1 HIPK2 ITGA1	2.04e-03	517	75	6	EFO_0010554
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS USH2A	2.15e-03	27	75	2	DOID:10584 (implicated_via_orthology)
Disease	Psychotic Disorders	SLC6A9 FEZ1 GRIK4	2.20e-03	101	75	3	C0033975

Protein segments in the cluster

Peptide	Gene	Start	Entry
WNGSDSVIMTGAYNN	PPP2R2C	346	Q9Y2T4
GMDASNGYRALQWNA	ARSD	106	P51689
SLWIGYSFLMHTAAG	COL4A6	1596	Q14031
NNIANMYSLHSWVGL	CYBRD1	111	Q53TN4
NHQMWLLFQTDGSGS	CSMD2	491	Q7Z408
LNDTTCWGTDYHLGM	ADAM20	586	O43506
AYMREHNQLNGWSSD	GPNMB	36	Q14956
WNGSDSAIMTGSYNN	PPP2R2D	356	Q66LE6
TYQGNAGDSMMWHNG	ANGPTL1	401	O95841
RGSGYLNWEQLHAAM	CAPN14	601	A8MX76
QGTHYSVQSDIWSMG	MAP2K1	236	Q02750
GTHYSVQSDIWSMGL	MAP2K2	241	P36507
ANSASSHNWNTLFMG	RBM19	506	Q9Y4C8
NEMFGYNGWAHSITQ	RAD52	76	P43351
TMWLGAQNGCLYVHS	SPAG9	971	O60271
MTSWASFHNGVAAGL	ANAPC1	1131	Q9H1A4
WGLSYMGTNMHSLQL	INPP1	221	P49441
MSQGLSWHDDLTQYV	PTPRN	91	Q16849
SSNWDMTGYGSHSKV	HIPK2	36	Q9H2X6
WYALMGAQTITSGHS	EYS	1596	Q5T1H1
SQGDHQMSWFSDLNL	IHO1	551	Q8IYA8
SGNWMNDYDSTSHAR	PHKA1	641	P46020
EGSWAQTLAYGDMNH	PPFIA4	931	O75335
SHDNEVYAWGNNSMG	HERC1	681	Q15751
GHGYNSSAAAWQAMQ	PNRC2	46	Q9NPJ4
QAMWYTDEDHGIASS	DPP4	731	P27487
MHWGYDSRLLVSASQ	GNB4	61	Q9HAV0
WYLLSMGSNENIHSI	F8	1961	P00451
NNNWSYEGLRHMSGS	FEZ1	216	Q99689
VSGGQWNHMLGYLAA	FAM120A	66	Q9NZB2
GSLFGFSLAMHWQLQ	ITGA6	41	P23229
SDAGWTLGYMLNLTN	ENTPD1	446	P49961
GFSAHYSQDWVMLGA	ITGA1	381	P56199
LGDWGKMISCSNHYN	HIPK3	711	Q9H422
GLMYHDASRWGLTLQ	TK2	96	O00142
STANYLGWAIMHASP	PEMT	146	Q9UBM1
MAGENHQWQGSILYN	NR0B1	1	P51843
GDYADHQQWMGLSDS	CRYGD	61	P07320
MQSALVGSWHNNGFY	C3orf84	1	H3BNL1
GYLSFALSHDQWMGD	FRRS1	241	Q6ZNA5
DSNLDWSHNFTNMLG	CS	231	O75390
ALGQGETSWYMHCSE	CMYA5	3971	Q8N3K9
MDWGANGQVTYSLHS	FAT3	2841	Q8TDW7
GNGWHSMASNYTGRC	HYAL3	206	O43820
AAAMAWGQGDFYNHA	A3GALT2	241	U3KPV4
DQQGHTMGALYWQLN	MANBA	646	O00462
DQHYLSWSMLLGVGF	GLMP	346	Q8WWB7
EKTSMHSLWAQLGGY	FAM186A	2306	A6NE01
GSAQIWQHGTSLMNY	GRIK4	336	Q16099
GWMSSHTDFGNINGC	SLC15A4	516	Q8N697
NAGSLFLMHYTANIW	SLC19A3	356	Q9BZV2
SHFSANWIFALAGGM	SLC39A14	421	Q15043
SINGMVNHSWSELYS	HCN2	401	Q9UL51
GHDTTSSGISWMLFN	CYP4F22	336	Q6NT55
ASWNGSMHNGALDNH	MN1	471	Q10571
GGNWYAMDNSGEHVT	IGF2R	791	P11717
YNSTGAELRHWSDML	SYT1	381	P21579
SLWEAIMGHNSGLYV	USH2A	5161	O75445
RMDSYAHMNGWSNGS	SOX2	156	P48431
SLLGAAHSSDYSMWR	SPON2	71	Q9BUD6
MSEGAYQRLWESSHA	IQCA1L	1	A6NCM1
VSYGDMAWHVNTNDS	NBEA	351	Q8NFP9
MLTSYIASCWNHDGD	PITRM1	446	Q5JRX3
WHSQAYALGAVSNFM	SLC25A53	26	Q5H9E4
QTHNNMYAWGQESGA	SEC23A	726	Q15436
HLASQYWGCSRTMAG	TBC1D9B	831	Q66K14
AMWYSDQNHGLSGLS	FAP	726	Q12884
AQEGMVLYGWTDHSA	VWF	276	P04275
KQSFMGNSGNSWSHT	RNF112	21	Q9ULX5
WASDTMYLGQLTAHS	IGHMBP2	451	P38935
WGGLITMASYNKFHN	SLC6A9	376	P48067
GSGSFDWHQSAMAKT	TSHZ3	161	Q63HK5
TSERWYHGHMSGGQA	PTPN6	106	P29350
TTINLNSMNDGWYGA	TJP1	771	Q07157
GGASRDFWMSSNLHQ	ZNF530	121	Q6P9A1
NDSQSWAHNMGSEDY	TEX15	121	Q9BXT5
SLGLNGMNSSIWEHF	UNK	611	Q9C0B0
LSEGTGGFSSWHMNN	ZNF106	206	Q9H2Y7
MANQSGWSDAFLAQH	TCIRG1	481	Q13488