Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	NANOGP8 NANOG	6.23e-05	4	65	2	GO:0001010
GeneOntologyBiologicalProcess	negative regulation of endodermal cell fate specification	NANOGP8 NANOG	5.66e-05	4	64	2	GO:0042664
GeneOntologyBiologicalProcess	regulation of endodermal cell fate specification	NANOGP8 NANOG	9.42e-05	5	64	2	GO:0042663
GeneOntologyBiologicalProcess	maintenance of centrosome location	SPOUT1 ASPM	1.41e-04	6	64	2	GO:0051661
GeneOntologyBiologicalProcess	negative regulation of endodermal cell differentiation	NANOGP8 NANOG	1.41e-04	6	64	2	GO:1903225
GeneOntologyCellularComponent	acrosomal vesicle	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 MORN3	3.97e-05	206	64	6	GO:0001669
GeneOntologyCellularComponent	inner dynein arm	DNAH12 DNAH2	4.09e-04	10	64	2	GO:0036156
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	5.34e-08	12	62	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	5.34e-08	12	62	4	IPR027970
Domain	PH	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	1.05e-05	229	62	7	PF00169
Domain	PH	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	3.67e-05	278	62	7	SM00233
Domain	PH_DOMAIN	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	3.75e-05	279	62	7	PS50003
Domain	PH_domain	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	3.84e-05	280	62	7	IPR001849
Domain	GDS_CDC24_CS	FARP1 PREX2 FARP2	2.92e-04	39	62	3	IPR001331
Domain	-	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	3.05e-04	391	62	7	2.30.29.30
Domain	HTH_MYB	DMTF1 MYBL1	3.85e-04	9	62	2	PS51294
Domain	Myb_dom	DMTF1 MYBL1	3.85e-04	9	62	2	IPR017930
Domain	PH_dom-like	AFAP1L2 FARP1 ARHGAP12 DOK3 ARHGAP25 PREX2 FARP2	5.10e-04	426	62	7	IPR011993
Domain	FERM-adjacent	FARP1 FARP2	8.26e-04	13	62	2	IPR014847
Domain	FA	FARP1 FARP2	8.26e-04	13	62	2	SM01195
Domain	FA	FARP1 FARP2	8.26e-04	13	62	2	PF08736
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH2	9.62e-04	14	62	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH2	9.62e-04	14	62	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH2	9.62e-04	14	62	2	PF08393
Domain	AAA_8	DNAH12 DNAH2	9.62e-04	14	62	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH2	9.62e-04	14	62	2	IPR011704
Domain	AAA_5	DNAH12 DNAH2	9.62e-04	14	62	2	PF07728
Domain	DHC_fam	DNAH12 DNAH2	1.11e-03	15	62	2	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH2	1.11e-03	15	62	2	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH2	1.11e-03	15	62	2	PF03028
Domain	DH_1	FARP1 PREX2 FARP2	1.20e-03	63	62	3	PS00741
Domain	Fatty_acid-bd	RBP7 RBP2	1.26e-03	16	62	2	IPR000463
Domain	FABP	RBP7 RBP2	1.26e-03	16	62	2	PS00214
Domain	iLBP	RBP7 RBP2	1.26e-03	16	62	2	IPR031259
Domain	RhoGEF	FARP1 PREX2 FARP2	1.50e-03	68	62	3	SM00325
Domain	RhoGEF	FARP1 PREX2 FARP2	1.63e-03	70	62	3	PF00621
Domain	DH_2	FARP1 PREX2 FARP2	1.63e-03	70	62	3	PS50010
Domain	DH-domain	FARP1 PREX2 FARP2	1.70e-03	71	62	3	IPR000219
Domain	-	FARP1 PREX2 FARP2	1.70e-03	71	62	3	1.20.900.10
Domain	Ez/rad/moesin-like	FARP1 FARP2	2.19e-03	21	62	2	IPR000798
Domain	FERM_CS	FARP1 FARP2	2.85e-03	24	62	2	IPR019747
Domain	FERM_C	FARP1 FARP2	3.35e-03	26	62	2	PF09380
Domain	THIOL_PROTEASE_CYS	CAPN3 CTSK	3.35e-03	26	62	2	PS00139
Domain	THIOL_PROTEASE_ASN	CAPN3 CTSK	3.61e-03	27	62	2	PS00640
Domain	THIOL_PROTEASE_HIS	CAPN3 CTSK	3.61e-03	27	62	2	PS00639
Domain	FERM_C	FARP1 FARP2	3.61e-03	27	62	2	SM01196
Domain	FERM_PH-like_C	FARP1 FARP2	3.61e-03	27	62	2	IPR018980
Domain	Pept_cys_AS	CAPN3 CTSK	3.88e-03	28	62	2	IPR000169
Domain	Homeodomain-like	DMTF1 NANOGP8 UBTF NANOG MYBL1	4.87e-03	332	62	5	IPR009057
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK8 FARP1 ARHGAP12 ARHGAP25 PREX2 FARP2	2.68e-05	175	48	6	MM15599
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK8 FARP1 ARHGAP12 ARHGAP25 PREX2 FARP2	3.55e-05	184	48	6	M41809
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	1.26e-13	6	66	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	1.26e-13	6	66	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	8.72e-10	24	66	5	32212159
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	TRANK1 DNAH12 P4HA1 UBTF PRPF8 SPATA31A6 ANO3 KMO TGM5	4.16e-07	497	66	9	36774506
Pubmed	Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.	NANOGP8 NANOG	3.55e-06	2	66	2	24598770
Pubmed	Differential expression of nanog1 and nanogp8 in colon cancer cells.	NANOGP8 NANOG	3.55e-06	2	66	2	22079639
Pubmed	Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.	NANOGP8 NANOG	3.55e-06	2	66	2	21136380
Pubmed	Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2.	FARP1 FARP2	3.55e-06	2	66	2	23375260
Pubmed	Functional evidence that the self-renewal gene NANOG regulates human tumor development.	NANOGP8 NANOG	3.55e-06	2	66	2	19415763
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	KLHL5 UBTF CEP250 POP1 ASPM PRPF8	5.64e-06	234	66	6	36243803
Pubmed	Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	25825768
Pubmed	Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation.	NANOGP8 NANOG	1.06e-05	3	66	2	31891567
Pubmed	Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.	NANOGP8 NANOG	1.06e-05	3	66	2	19447925
Pubmed	The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.	NANOGP8 NANOG	1.06e-05	3	66	2	30814124
Pubmed	Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.	NANOGP8 NANOG	1.06e-05	3	66	2	14728807
Pubmed	Isolation and characterization of the murine Nanog gene promoter.	NANOGP8 NANOG	1.06e-05	3	66	2	15916719
Pubmed	The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	30846691
Pubmed	Generation of germline-competent induced pluripotent stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	17554338
Pubmed	Multiple phases in regulation of Nanog expression during pre-implantation development.	NANOGP8 NANOG	1.06e-05	3	66	2	26660234
Pubmed	Nanog retrotransposed genes with functionally conserved open reading frames.	NANOGP8 NANOG	1.06e-05	3	66	2	16845474
Pubmed	Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.	NANOGP8 NANOG	1.06e-05	3	66	2	21194951
Pubmed	Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.	NANOGP8 NANOG	1.06e-05	3	66	2	22388986
Pubmed	NANOG changes in mouse kidneys with age.	NANOGP8 NANOG	1.06e-05	3	66	2	16313224
Pubmed	Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.	NANOGP8 NANOG	1.06e-05	3	66	2	18177668
Pubmed	Nanog promotes transfer of pluripotency after cell fusion.	NANOGP8 NANOG	1.06e-05	3	66	2	16791199
Pubmed	Expression of Nanog gene promotes NIH3T3 cell proliferation.	NANOGP8 NANOG	1.06e-05	3	66	2	16259959
Pubmed	Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6.	NANOGP8 NANOG	1.06e-05	3	66	2	33665763
Pubmed	A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	12609610
Pubmed	Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	18024963
Pubmed	CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts.	TNFRSF11A CTSK	1.06e-05	3	66	2	26195726
Pubmed	The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	27125671
Pubmed	Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.	NANOGP8 NANOG	1.06e-05	3	66	2	24227785
Pubmed	Beclin1 Modulates Bone Homeostasis by Regulating Osteoclast and Chondrocyte Differentiation.	TNFRSF11A CTSK	1.06e-05	3	66	2	31074883
Pubmed	Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.	NANOGP8 NANOG	1.06e-05	3	66	2	22028025
Pubmed	Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.	NANOGP8 NANOG	1.06e-05	3	66	2	28457890
Pubmed	Requirement of Nanog dimerization for stem cell self-renewal and pluripotency.	NANOGP8 NANOG	1.06e-05	3	66	2	18436640
Pubmed	Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	25410303
Pubmed	Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.	NANOGP8 NANOG	1.06e-05	3	66	2	24929238
Pubmed	Nanog and transcriptional networks in embryonic stem cell pluripotency.	NANOGP8 NANOG	1.06e-05	3	66	2	17211451
Pubmed	The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.	NANOGP8 NANOG	1.06e-05	3	66	2	23770853
Pubmed	The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.	NANOGP8 NANOG	1.06e-05	3	66	2	15502159
Pubmed	Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment.	NANOGP8 NANOG	1.06e-05	3	66	2	33334884
Pubmed	NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation.	NANOGP8 NANOG	1.06e-05	3	66	2	21499299
Pubmed	Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.	NANOGP8 NANOG	1.06e-05	3	66	2	20574542
Pubmed	lincRNAs act in the circuitry controlling pluripotency and differentiation.	NANOGP8 NANOG	1.06e-05	3	66	2	21874018
Pubmed	Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.	NANOGP8 NANOG	1.06e-05	3	66	2	23054952
Pubmed	Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self-renewal.	NANOGP8 NANOG	1.06e-05	3	66	2	33107035
Pubmed	Nanog-independent reprogramming to iPSCs with canonical factors.	NANOGP8 NANOG	1.06e-05	3	66	2	24527385
Pubmed	Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	18086680
Pubmed	Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.	NANOGP8 NANOG	1.06e-05	3	66	2	17360937
Pubmed	H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate.	NANOGP8 NANOG	1.06e-05	3	66	2	35976266
Pubmed	Nanog dynamics in single embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	26760119
Pubmed	Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	17204467
Pubmed	CrxOS maintains the self-renewal capacity of murine embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	19800316
Pubmed	Nanog is dispensable for the generation of induced pluripotent stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	24461999
Pubmed	Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	23200040
Pubmed	Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.	NANOGP8 NANOG	1.06e-05	3	66	2	26975336
Pubmed	Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.	NANOGP8 NANOG	1.06e-05	3	66	2	23329853
Pubmed	Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.	NANOGP8 NANOG	1.06e-05	3	66	2	30837263
Pubmed	NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.	NANOGP8 NANOG	1.06e-05	3	66	2	26751055
Pubmed	Nanog induces hyperplasia without initiating tumors.	NANOGP8 NANOG	1.06e-05	3	66	2	25173648
Pubmed	Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.	NANOGP8 NANOG	1.06e-05	3	66	2	27939294
Pubmed	Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	17352742
Pubmed	OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.	NANOGP8 NANOG	1.06e-05	3	66	2	23178592
Pubmed	Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.	NANOGP8 NANOG	1.06e-05	3	66	2	25005472
Pubmed	Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification.	NANOGP8 NANOG	1.06e-05	3	66	2	24681518
Pubmed	Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.	NANOGP8 NANOG	1.06e-05	3	66	2	16773043
Pubmed	Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.	NANOGP8 NANOG	1.06e-05	3	66	2	23665121
Pubmed	Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.	NANOGP8 NANOG	1.06e-05	3	66	2	26733157
Pubmed	Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.	NANOGP8 NANOG	1.06e-05	3	66	2	26549484
Pubmed	mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.	NANOGP8 NANOG	1.06e-05	3	66	2	23071603
Pubmed	Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.	NANOGP8 NANOG	1.06e-05	3	66	2	16501172
Pubmed	Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	19582141
Pubmed	Identification of genes regulated by nanog which is involved in ES cells pluripotency and early differentiation.	NANOGP8 NANOG	1.06e-05	3	66	2	18442017
Pubmed	NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.	NANOGP8 NANOG	1.06e-05	3	66	2	21119109
Pubmed	Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	32145514
Pubmed	Nanog is the gateway to the pluripotent ground state.	NANOGP8 NANOG	1.06e-05	3	66	2	19703398
Pubmed	Nanog safeguards pluripotency and mediates germline development.	NANOGP8 NANOG	1.06e-05	3	66	2	18097409
Pubmed	Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.	NANOGP8 NANOG	1.06e-05	3	66	2	28636920
Pubmed	De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis.	TNFRSF11A CTSK	1.06e-05	3	66	2	38489269
Pubmed	Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst.	NANOGP8 NANOG	1.06e-05	3	66	2	25753417
Pubmed	A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.	NANOGP8 NANOG	1.06e-05	3	66	2	20539761
Pubmed	Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.	NANOGP8 NANOG	1.06e-05	3	66	2	18584034
Pubmed	Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	21969378
Pubmed	The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.	NANOGP8 NANOG	1.06e-05	3	66	2	20661723
Pubmed	NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.	NANOGP8 NANOG	1.06e-05	3	66	2	29245050
Pubmed	Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.	NANOGP8 NANOG	1.06e-05	3	66	2	22337995
Pubmed	Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.	NANOGP8 NANOG	1.06e-05	3	66	2	21187909
Pubmed	Functional analysis of two Sp1/Sp3 binding sites in murine Nanog gene promoter.	NANOGP8 NANOG	1.06e-05	3	66	2	16541131
Pubmed	Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.	NANOGP8 NANOG	1.06e-05	3	66	2	22142851
Pubmed	The pluripotency rheostat Nanog functions as a dimer.	NANOGP8 NANOG	1.06e-05	3	66	2	18290762
Pubmed	NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.	NANOGP8 NANOG	1.06e-05	3	66	2	24462001
Pubmed	Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.	NANOGP8 NANOG	1.06e-05	3	66	2	23333380
Pubmed	A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal.	NANOGP8 NANOG	1.06e-05	3	66	2	16790525
Pubmed	Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.	NANOGP8 NANOG	1.06e-05	3	66	2	22172669
Pubmed	Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.	NANOGP8 NANOG	1.06e-05	3	66	2	23103910
Pubmed	Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.	NANOGP8 NANOG	1.06e-05	3	66	2	15494369
Pubmed	The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells.	NANOGP8 NANOG	2.12e-05	4	66	2	25743411
Pubmed	Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol.	RBP7 RBP2	2.12e-05	4	66	2	11022035
Pubmed	CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog.	NANOGP8 NANOG	2.12e-05	4	66	2	22315219
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	5.50e-05	8	65	2	chr9q12
Cytoband	9p13.1	SPATA31A1 SPATA31A3	5.34e-04	24	65	2	9p13.1
Cytoband	8q22.1	RAD54B POP1	1.49e-03	40	65	2	8q22.1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AFAP1L2 FARP1 ARHGAP12 ARHGAP25 FARP2	6.76e-05	206	38	5	682
GeneFamily	SPOUT methyltranferase domain containing	TRMT10A SPOUT1	1.19e-04	8	38	2	1294
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FARP1 PREX2 FARP2	3.58e-04	66	38	3	722
GeneFamily	Fatty acid binding protein family	RBP7 RBP2	5.07e-04	16	38	2	550
GeneFamily	Dyneins, axonemal	DNAH12 DNAH2	5.73e-04	17	38	2	536
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP12 ARHGAP25	4.94e-03	50	38	2	721
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FARP1 FARP2	4.94e-03	50	38	2	1293
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	DMTF1 MYBL1	5.54e-03	53	38	2	532
GeneFamily	NKL subclass homeoboxes and pseudogenes	NANOGP8 NANOG	8.73e-03	67	38	2	519
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200	TRANK1 MYBL1	8.66e-06	2	63	2	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_200
CoexpressionAtlas	PP_HSC_top-relative-expression-ranked_500_k-means-cluster#5	GVINP1 DOCK8 TMC8 ARHGAP25 PRKG2 CLEC2B	3.60e-05	209	63	6	PP_HSC_500_K5
CoexpressionAtlas	PP_HSC_top-relative-expression-ranked_1000_k-means-cluster#1	TRANK1 DOCK8 DOK3 TMC8 ARHGAP25 PRKG2 CLEC2B	7.00e-05	344	63	7	PP_HSC_1000_K1
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	RBP7 AFAP1L2 RAD54B CDH10 PREX2	4.49e-06	169	64	5	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMC8 ARHGAP25 PRKG2 UNC5D MYBL1	5.94e-06	179	64	5	db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBP7 TRMT10A ABCA12 RBP2 TGM5	8.78e-06	194	64	5	bd94d30584128628b34ed8c3857ce103586cfe2e
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte-new-cluster\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBP7 TRMT10A ABCA12 RBP2 TGM5	8.78e-06	194	64	5	b847c5b4e8914b1c306bfff3d7119c32063784a8
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ARHGAP25 CLEC2B MYBL1	9.93e-06	199	64	5	b947ecaf912d97869f6df32736b8c2b2dd695d66
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ARHGAP25 CLEC2B MYBL1	1.02e-05	200	64	5	be9a43acc2f926b9433ab3f018b911b03896a924
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ARHGAP25 CLEC2B MYBL1	1.02e-05	200	64	5	c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ARHGAP25 CLEC2B MYBL1	1.02e-05	200	64	5	893bb7c25ad7c6589a4c7c0364c2ace666e9b4be
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ARHGAP25 CLEC2B MYBL1	1.02e-05	200	64	5	dbbc7e16929e744b48017da068479a6046e99cf6
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-\|Striatum / BrainAtlas - Mouse McCarroll V32	DNAH12 NANOG RBP2 MORN3	2.45e-05	117	64	4	26dec09112532f351fb7a2202bae84c365707b40
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)\|Striatum / BrainAtlas - Mouse McCarroll V32	DNAH12 NANOG RBP2 MORN3	2.45e-05	117	64	4	db053c874e6739052dff1f91643e51b306236237
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--\|Striatum / BrainAtlas - Mouse McCarroll V32	DNAH12 NANOG RBP2 MORN3	2.45e-05	117	64	4	80780223502d18f0d86a29ff3cb74aa8235103c7
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL\|Striatum / BrainAtlas - Mouse McCarroll V32	DNAH12 NANOG RBP2 MORN3	2.45e-05	117	64	4	40889f4a387846abbf54469cc4faf616bfe348d0
ToppCell	Striatum-Macroglia-CSF_related\|Striatum / BrainAtlas - Mouse McCarroll V32	DNAH12 NANOG RBP2 MORN3	2.45e-05	117	64	4	e12e37e393257db85f7f5c13454095c44f59d374
ToppCell	facs-MAT-Fat-24m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 CEP250 TMC8 MYBL1	6.80e-05	152	64	4	fa03262e2853b7d35ef8cdbb652930abad90563c
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Mast-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK8 CEP250 PITPNA POP1	8.09e-05	159	64	4	81782e9e370558d61af5e0c760ac9759d69fb725
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GLT8D2 EVC2 CAPN3 PRKG2	8.49e-05	161	64	4	e3327c296d48e821004e61a573abb75624a6f040
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK8 ABCA12 DOK3 TNFRSF11A	8.70e-05	162	64	4	9d6931619f5eb847c79d00ff5ae031fef30fd55c
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	TRMT10A ASPM TNFRSF11A TGM5	9.12e-05	164	64	4	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	EVC2 PITPNA RAD54B CTSK	9.12e-05	164	64	4	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	EVC2 PITPNA RAD54B CTSK	9.12e-05	164	64	4	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TRMT10A EVC2 ASPM TGM5	9.34e-05	165	64	4	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	GLT8D2 TNFRSF11A SLC24A1 PREX2	9.56e-05	166	64	4	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFAP1L2 RAD54B ASPM MYBL1	1.17e-04	175	64	4	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	TREH PGM2L1 TNFRSF11A SLC24A1	1.20e-04	176	64	4	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	3'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK8 DOK3 ARHGAP25 MYBL1	1.25e-04	178	64	4	da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell	LA-17._Lymphocyte\|World / Chamber and Cluster_Paper	DOCK8 TMC8 ARHGAP25 MYBL1	1.25e-04	178	64	4	34ec499d03cc198cfefa19a724d4c81974052f65
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK8 DOK3 ARHGAP25 MYBL1	1.25e-04	178	64	4	580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCell	facs-Skin-Anagen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 ABCA12 RBP2 LARS2	1.28e-04	179	64	4	4a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 ARHGAP25 ANO3 CDH10	1.28e-04	179	64	4	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAD54B ASPM SLBP MYBL1	1.31e-04	180	64	4	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	facs-Heart-LV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK3 SLBP ARHGAP25 KMO	1.33e-04	181	64	4	57f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCell	facs-Heart-LV-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK3 SLBP ARHGAP25 KMO	1.33e-04	181	64	4	8855812c85ef45c1be6bd511619b2dfe5e441264
ToppCell	LA-17._Lymphocyte\|LA / Chamber and Cluster_Paper	DOCK8 TMC8 ARHGAP25 MYBL1	1.33e-04	181	64	4	3fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NANOG SCTR MORN3	1.35e-04	69	64	3	2fd6df70cdc7477e4a3ebdf4537279a727ab1214
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NANOG SCTR MORN3	1.35e-04	69	64	3	8e14f411cbaea9cb9bcb9351b2421e71d5828ccc
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NANOG SCTR MORN3	1.35e-04	69	64	3	bc3170409d107c39534581d2f0b8d75f93519113
ToppCell	RA-17._Lymphocyte\|RA / Chamber and Cluster_Paper	DOCK8 TMC8 ARHGAP25 MYBL1	1.36e-04	182	64	4	257a7847917b6ea1d60608183d90300bfd028758
ToppCell	facs-Heart-LV-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK3 SLBP ARHGAP25 KMO	1.36e-04	182	64	4	d0d18dd5d8b2d21e42c3c4259f824c91f24a54bc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 AFAP1L2 ASPM ANO3	1.36e-04	182	64	4	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 AFAP1L2 ASPM ANO3	1.36e-04	182	64	4	05c167158815bf25d509df59ab386e1990712765
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GVINP1 RAD54B ASPM KMO	1.39e-04	183	64	4	ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GVINP1 RAD54B ASPM KMO	1.39e-04	183	64	4	e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GVINP1 RAD54B ASPM KMO	1.39e-04	183	64	4	263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 ASPM ARHGAP25 CDH10	1.39e-04	183	64	4	3ebe334ad570e3525341badb558f369c61daf3d3
ToppCell	RA-17._Lymphocyte\|World / Chamber and Cluster_Paper	DOCK8 TMC8 ARHGAP25 MYBL1	1.39e-04	183	64	4	6397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	WDR87 SLC24A1 MORN3	1.40e-04	70	64	3	2121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	WDR87 SLC24A1 MORN3	1.40e-04	70	64	3	cd6bca68fe52f451716fc8c0b1745984bc9ec057
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	WDR87 SLC24A1 MORN3	1.40e-04	70	64	3	be300c0447735aba89df4c3082b81eb5abf22770
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 ABCA12 ANO3 UNC5D	1.42e-04	184	64	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 ABCA12 ANO3 UNC5D	1.42e-04	184	64	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 ABCA12 ANO3 UNC5D	1.42e-04	184	64	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK8 TMC8 ARHGAP25 MYBL1	1.45e-04	185	64	4	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	DOCK8 TMC8 ARHGAP25 MYBL1	1.51e-04	187	64	4	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	facs-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 ABCA12 RBP2 TGM5	1.54e-04	188	64	4	ed35e438796cef302b6787c111753425922792dc
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 ASPM UNC5D PREX2	1.54e-04	188	64	4	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.57e-04	189	64	4	b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.57e-04	189	64	4	823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCell	SupraBC-Differ-KC\|World / shred by cell class for mouse tongue	RBP7 ABCA12 ANO3 TGM5	1.57e-04	189	64	4	6412741b88e241304033b41effca0c77a374d907
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.57e-04	189	64	4	47c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 KLHL5 AFAP1L2 PREX2	1.61e-04	190	64	4	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 ASPM UNC5D PREX2	1.61e-04	190	64	4	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DMTF1 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	ba61f04fd38efae01f721ba616252d1372ff1002
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK8 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TMC8 ARHGAP25 QSOX2 KMO	1.61e-04	190	64	4	424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	07ea0578ca0561077557203ae660530f53fc4067
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	5a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.61e-04	190	64	4	5b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 TNFRSF11A	1.64e-04	191	64	4	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.64e-04	191	64	4	d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.64e-04	191	64	4	b42c54308abe1241cc38ddce96b9d38d07983891
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.64e-04	191	64	4	96a7179a845d3daa046ed71fa45c51255f130a7f
ToppCell	Fetal_29-31_weeks-Immune-B_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TMC8 ARHGAP25 QSOX2 KMO	1.64e-04	191	64	4	84452125d1b5b76974e3f9126f611eff16d45c25
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 TNFRSF11A	1.64e-04	191	64	4	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	facs-Tongue-nan-18m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 ABCA12 RBP2 TGM5	1.64e-04	191	64	4	02f24202f9fdd46c648265a5b3b6f9066aa009fc
ToppCell	COVID-19-lung-CD8+_T_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK8 TMC8 CLEC2B MYBL1	1.64e-04	191	64	4	543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 MYBL1	1.64e-04	191	64	4	9aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 KLHL5 AFAP1L2 PREX2	1.67e-04	192	64	4	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	DOCK8 DOK3 ASPM ARHGAP25	1.67e-04	192	64	4	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	facs-Trachea-nan-18m-Epithelial-keratinocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 ABCA12 RBP2 TGM5	1.67e-04	192	64	4	4530b3028928d089b3a71eb19a4df237f58a50ae
ToppCell	Nasal_Brush-Immune-Neutrophils\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	RBP7 DOCK8 DOK3 ARHGAP25	1.67e-04	192	64	4	20a7f7beb01df1c4f915ec2f9b5a9dbcab157187
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RBP7 DOCK8 DOK3 KMO	1.67e-04	192	64	4	d44f46352bac414b45cc749f7cbdc3a159bd7ae8
ToppCell	facs-Trachea-nan-18m-Epithelial-new-cluster\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 ABCA12 RBP2 TGM5	1.67e-04	192	64	4	e4fb3f18da7dc6a835023db69a8d99737c39ef86
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP7 KLHL5 AFAP1L2 PREX2	1.67e-04	192	64	4	bcd8876235be503186f119653b39476488c0fa15
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMC8 ARHGAP25 CLEC2B MYBL1	1.77e-04	195	64	4	073593a7f668512d1fbbb49efb0c20b736c79ff8
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK8 TMC8 TNFRSF11A KMO	1.77e-04	195	64	4	c707885d092aedbbe14f51f7de4a5911c9214289
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMC8 ARHGAP25 CLEC2B MYBL1	1.77e-04	195	64	4	6774c9f7fa54045aaa35fbd0695e43748da2b293
ToppCell	control-Lymphoid\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK8 TMC8 ARHGAP25 MYBL1	1.81e-04	196	64	4	8ed172bb3a95f09722476f0880ae246561777d98
ToppCell	mLN-B_cell-B_cell_cycling\|mLN / Region, Cell class and subclass	TRMT10A RAD54B ASPM MYBL1	1.84e-04	197	64	4	806dddcca85c82bd642008d930c8db16b613d88e
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TRANK1 TMC8 ARHGAP25 MYBL1	1.84e-04	197	64	4	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	mLN-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	TRMT10A RAD54B ASPM MYBL1	1.84e-04	197	64	4	2071526fe46de8359ea118ff78581eb4454aa55a
ToppCell	NS-control-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK8 TMC8 ARHGAP25 MYBL1	1.84e-04	197	64	4	bd3f2d68eb108fe31e217c9124183920e7c82582
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 TMC8 ARHGAP25 TNFRSF11A	1.84e-04	197	64	4	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AFAP1L2 DOCK8 TMC8 TNFRSF11A	1.84e-04	197	64	4	9791923feefbd78810242113ad2a08ce4c2bb4f2
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	TMC8 ARHGAP25 CLEC2B MYBL1	1.84e-04	197	64	4	4b480a527bc1d77e35b310287be8741e5f62b7f0
ToppCell	mLN-(2)_B_cell-(24)_B_cell_cycling\|mLN / shred on region, Cell_type, and subtype	TRMT10A RAD54B ASPM MYBL1	1.84e-04	197	64	4	70fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCell	distal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH12 ABCA12 DNAH2 MORN3	1.84e-04	197	64	4	15b4d1203943ce90a7083178d4a4284d9b323071
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 CLEC2B MYBL1	1.92e-04	199	64	4	bc93e5c36ab60b66fb633c954b05d4dc09a7f152
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 TMC8 ASPM CLEC2B	1.92e-04	199	64	4	868ff080f72b6274a84e3ae0ddee4a32ed96472a
Disease	colon cancer (implicated_via_orthology)	NANOGP8 NANOG	2.06e-04	11	58	2	DOID:219 (implicated_via_orthology)
Disease	Disproportionate short stature	EVC2 IFT80 CTSK	4.75e-04	77	58	3	C0878659
Disease	fumarate measurement	AFAP1L2 LARS2	7.78e-04	21	58	2	EFO_0010480
Disease	Primary microcephaly	TRMT10A ASPM	8.55e-04	22	58	2	C0431350
Disease	retinitis pigmentosa (implicated_via_orthology)	CEP250 PRPF8	1.29e-03	27	58	2	DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
WELWKKTHRKQYNNK	CTSK	26	P43235
QKGNKHWIIKNSWGE	CTSK	286	P43235
HQLQILVWKNWLGVK	ABCA12	6	Q86UK0
HEKQKYWWSLVQTVK	GVINP1	1366	Q7Z2Y8
KWLGQWAKQLCVIKD	AFAP1L2	186	Q8N4X5
WLLAQKGKKNDWKHN	GIP	76	P09681
RSKWWTIKRQIANHK	DMTF1	381	Q9Y222
HLWKDVGERQKVLNW	ASPM	801	Q8IZT6
IQNWWSRHKIKRGIH	ANO3	716	Q9BYT9
LVNNWKKEFQKWLGS	RAD54B	366	Q9Y620
ILWLWKKHNMVNGRL	QSOX2	501	Q6ZRP7
KWWGLQNKVENFIHK	PITPNA	201	Q00169
EKNKQWGKDSLLNKW	nan	921	O00370
KWNKHIEVWVKEQLS	SLC24A1	601	O60721
QWLRWDKNPKTKEQI	PGM2L1	31	Q6PCE3
LKNKGRWVHWNELIK	DNAH12	1836	Q6ZR08
KRWQKNNWPKNSNGV	NANOG	151	Q9H9S0
RKHQSWWQALDGKLR	EVC2	1186	Q86UK5
QQHVKFGKKCWRKVW	DOK3	71	Q7L591
TEWKHQRITKQLEKW	GLT8D2	236	Q9H1C3
VKQILKIRWRWFGHQ	KLHL5	56	Q96PQ7
KAVLQAVSDGQWWKK	NBAS	1426	A2RRP1
KKHRWLNGFNWEGLK	PRKG2	706	Q13237
AENGKKVRKNWLSSW	ARHGAP12	476	Q8IWW6
LVGNKWVSNKWLHER	P4HA1	506	P13674
QKKNIWLETHIWHAK	POP1	196	Q99575
QHWEWKNFQVTLTKR	IFT80	301	Q9P2H3
AVQRWHWQKKVINKG	KMO	411	O15229
GLNENLRWKKEQTHW	DOCK8	1391	Q8NF50
GKILHRQKRGWMWNQ	CDH10	46	Q9Y6N8
RKFKNSNGWQKLWVV	FARP1	941	Q9Y4F1
KWEKERSWHQQELAK	CEP250	861	Q9BV73
RHSVVEKQGEWHKKW	HAUS6	366	Q7Z4H7
LLRKFKNSHGWQKLW	FARP2	936	O94887
EFHHLWNKIKAWQKI	CAPN3	716	P20807
QKHKNWRFQKTRQTW	C7orf50	111	Q9BRJ6
LNKRDKWVKEWAGQV	DNAH2	1636	Q9P225
QKGLKKLWNRVKWTR	MYBL1	26	P10243
GQRIEWRKWKQQKKE	SPOUT1	16	Q5T280
EWAKKIQSEKFRWHN	KIFAP3	666	Q92845
EWKDNVKHGKGTQVW	MORN3	41	Q6PF18
RSWDQQIKLWKVALH	SLBP	181	Q14493
KWWHQRIKEQASKIS	LARS2	61	Q15031
EQHIKKWIIQHWGNL	SPATA31A6	596	Q5VVP1
KRWQKNNWPKNSNGV	NANOGP8	151	Q6NSW7
QHIKKWIIQHWGNLG	SPATA31A7	601	Q8IWB4
VLWSQQDVCKWLKKH	SAMD10	116	Q9BYL1
CVQKGEKENRGWKQW	RBP2	96	P50120
HWIGLKMAKNRTGQW	CLEC2B	91	Q92478
HEGKLIWWKDNKNKT	ERVK-25	806	P63136
NKNKTWEIGKVITWG	ERVK-25	816	P63136
VWAGQKRLGQLAKWK	PRPF8	1826	Q6P2Q9
QHIKKWIIQHWGNLG	SPATA31A3	601	Q5VYP0
HRLRKQLVWQVQEKW	TMC8	626	Q8IU68
QHIKKWIIQHWGNLG	SPATA31A1	601	Q5TZJ5
QHIKKWIIQHWGNLG	SPATA31A5	601	Q5VU36
CIQKGEKKNRGWTHW	RBP7	96	Q96R05
GWLKKQRSIVKNWQQ	ARHGAP25	51	P42331
QLEVQKKWQQWHLRE	SCTR	396	P47872
AWAGQLHQLWKKLGK	TREH	126	O43280
NGWKIHNTAKNKWFV	PREX2	326	Q70Z35
GNKKKDTIWNFHVWN	TGM5	326	O43548
WNIHLKKRTQQGKWE	UNC5D	631	Q6UXZ4
ENDKGWVNWKDIHIK	TRMT10A	156	Q8TBZ6
HEGKLIWWKDNKNKT	ERVK-19	811	Q9WJR5
NKNKTWEIGKVITWG	ERVK-19	821	Q9WJR5
SHFNKVGKNVDKWLW	TYW1	186	Q9NV66
WQSVIEKLAKKGLWH	TRANK1	126	O15050
GKQWSQLSDKKRLKW	UBTF	231	P17480
KKAWDEWKQVHGETR	WDR87	1461	Q6ZQQ6
RKKGKALTANLWHWI	TNFRSF11A	236	Q9Y6Q6