Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainIg_I-set

NRG2 NPTN MYLK DSCAML1

1.21e-03190464IPR013098
DomainI-set

NRG2 NPTN MYLK DSCAML1

1.21e-03190464PF07679
DomainIGc2

NRG2 NPTN MYLK DSCAML1

2.63e-03235464SM00408
DomainIg_sub2

NRG2 NPTN MYLK DSCAML1

2.63e-03235464IPR003598
Domain-

HPSE2 MANBA

3.35e-03354623.20.20.80
DomainIG

NRG2 NPTN MYLK DSCAML1 CD96

3.64e-03421465SM00409
DomainIg_sub

NRG2 NPTN MYLK DSCAML1 CD96

3.64e-03421465IPR003599
DomainGlyco_hydro_catalytic_dom

HPSE2 MANBA

3.94e-0338462IPR013781
DomainCUB

CSMD2 NRP1

6.48e-0349462PF00431
DomainCUB

CSMD2 NRP1

6.74e-0350462SM00042
DomainIG_LIKE

NRG2 NPTN MYLK DSCAML1 CD96

6.95e-03491465PS50835
Domain-

CSMD2 NRP1

7.28e-03524622.60.120.290
DomainCUB

CSMD2 NRP1

7.55e-0353462PS01180
DomainGlycoside_hydrolase_SF

HPSE2 MANBA

7.55e-0353462IPR017853
DomainIg-like_dom

NRG2 NPTN MYLK DSCAML1 CD96

7.67e-03503465IPR007110
DomainCUB_dom

CSMD2 NRP1

8.69e-0357462IPR000859
Domain-

PITPNM1 ATP8B2

1.09e-02644623.40.50.1000
DomainZinc_finger_PHD-type_CS

TRIM33 PHF19

1.12e-0265462IPR019786
Pubmed

A family of protein-deglutamylating enzymes associated with neurodegeneration.

MYLK TTLL4

3.90e-05748221074048
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 TRIM33 MTUS1 SRRM4 TIAM2 TTLL4

8.59e-0552948614621295
Pubmed

Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala.

DLX5 TIAM2

1.44e-041348221452241
Pubmed

Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

GPR158 DSCAML1 ATP8B2

1.62e-047648310574461
Pubmed

Neural crest cell-derived VEGF promotes embryonic jaw extension.

DLX5 NRP1

1.68e-041448225922531
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GPR158 DSCAML1 MAPK8IP3

2.41e-048748312465718
Pubmed

Arx homeobox gene is essential for development of mouse olfactory system.

DLX5 NRP1

2.50e-041748215677725
Pubmed

Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).

MAPK8IP3 NRP1

3.49e-042048212897243
Pubmed

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.

AKAP6 DLX5

6.89e-042848224427155
Pubmed

Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.

DLX5 TIAM2

6.89e-042848220392955
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MRPL21 LRWD1 RALGAPA2 POM121C TIAM2 TTLL4 MAPK8IP3

7.57e-04110548735748872
Pubmed

Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.

DLX5 NRP1

7.92e-043048238636517
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

RALGAPA2 MTUS1 DSCAML1

1.16e-0314948322664934
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NRG2 NPTN MYLK DSCAML1

1.79e-04161324593
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPTN CLEC9A PEAK1 RALGAPA2 NRP1

2.30e-06198485f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

AKAP6 NRG2 HPSE2 FAM171B

1.57e-051404845623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HPSE2 CSMD2 GPR158 LRP1B

1.95e-05148484d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C|TCGA-Thymus / Sample_Type by Project: Shred V9

MUC16 DSCAML1 SLC37A4 PLA2G3

2.85e-051634842dac87d15051151ccf193760ddd8b82534c3f922
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FNIP2 THAP10 MTUS1 ATP8B2

2.92e-051644841aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S XKR7 CLEC9A DSCAML1

3.21e-051684840e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCellCOVID-mDC1-|COVID / Condition, Cell_class and T cell subcluster

AKAP6 CLEC9A MYLK DSCAML1

3.76e-0517548483a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCellCOVID-mDC1|COVID / Condition, Cell_class and T cell subcluster

AKAP6 CLEC9A MYLK DSCAML1

3.76e-05175484b9280444016e21c28131a61df65cc5c56d402412
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

AKAP6 XKR7 DLX5 SRRM4

4.11e-05179484df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

FNIP2 AKAP6 CLEC9A MYLK

4.48e-05183484e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B DSCAML1 CD96 NRP1

4.58e-05184484d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

AKAP6 XKR7 DLX5 SRRM4

4.67e-05185484512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 HPSE2 MYLK MTUS1

4.77e-051864846add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 HPSE2 MYLK MTUS1

4.98e-05188484293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

HPSE2 DLX5 RALGAPA2 NRP1

5.18e-0519048462a3ec1ae0829602b0569cc051210551644f1d46
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 XKR7 MTUS1 SRRM4

5.40e-05192484307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

HPSE2 PEAK1 MYLK NRP1

5.40e-0519248462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

DLX5 DSCAML1 SRRM4 TIAM2

5.85e-05196484556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 HPSE2 MYLK LRP1B

5.85e-051964849830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A PEAK1 RALGAPA2 NRP1

5.97e-05197484deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A PEAK1 RALGAPA2 NRP1

5.97e-05197484a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 XKR7 MTUS1 SRRM4

5.97e-05197484a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 HPSE2 MYLK LRP1B

6.08e-0519848422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

TRIM33 DLX5 TIAM2 NRP1

6.08e-05198484de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellSepsis-Bac-SEP-Myeloid-cDC1|Bac-SEP / Disease, condition lineage and cell class

FNIP2 AKAP6 CLEC9A MYLK

6.33e-05200484cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 HPSE2 MYLK MTUS1

6.33e-05200484dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ComputationalNeighborhood of SIRT2

PEAK1 MTUS1 MAPK8IP3

2.17e-0444293GCM_SIRT2
Diseasecorpus callosum volume measurement

EEF1AKMT2 FAM171B NRP1

5.16e-04100463EFO_0010299
DiseaseRS-warfarin measurement

CLEC9A LRP1B DSCAML1

1.06e-03128463EFO_0803325
Diseasewhite matter volume measurement

GPR158 LRP1B

1.14e-0332462EFO_0008320
Diseasesystolic blood pressure, body mass index

AKAP6 CACNA1S

1.29e-0334462EFO_0004340, EFO_0006335
Diseaseresponse to TNF antagonist

CSMD2 CD96

3.23e-0354462EFO_0004653
Diseaselobe attachment

CACNA1S TTLL4 NRP1

4.14e-03207463EFO_0007667
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

CACNA1S NRP1 TDRP

4.66e-03216463EFO_0007925, EFO_0007927

Protein segments in the cluster

PeptideGeneStartEntry
IVTSSSNSVYLRWSS

CSMD2

2436

Q7Z408
SASWYTSAASSINSH

DLX5

256

P56178
LALSSFTTRSSSSWI

ATP8B2

1171

P98198
RLQWSSTELAYFSLS

LRWD1

546

Q9UFC0
RTSYNHRSWISTTSS

MUC16

12021

Q8WXI7
SDIRSSSLTLSWYGS

MYLK

1341

Q15746
DTLYWTSSTTSSITR

LRP1B

2281

Q9NZR2
TIWQFFSRLFSSSSS

MAPK8IP3

571

Q9UPT6
RSGSTSSLSYSTWTS

MTUS1

196

Q9ULD2
RSGSYLNSSINSAWS

GPR158

691

Q5T848
SSAIRYQEVWTSSTS

PEAK1

526

Q9H792
LYVNSVSTTLSSWSG

NRG2

326

O14511
WVSRINSDGSSTSYA

IGHV3-74

66

A0A0B4J1X5
WNSSSALSLLKYSAS

HPSE2

236

Q8WWQ2
KRSSSWGRTYSFTSA

RALGAPA2

476

Q2PPJ7
TSSYSSTRGISQLWK

POM121C

391

A8CG34
ITASSQYSTNWSAER

NRP1

291

O14786
ATILAQSYSWRSTLA

SLC37A4

156

O43826
QSYSWRSTLALSGAL

SLC37A4

161

O43826
YWTSLSNLVASLLNS

CACNA1S

541

Q13698
SAHSTRNRYSSQWTL

DSCAML1

1736

Q8TD84
PSSSTSSSSSYQRRW

FNIP2

256

Q9P278
SSSSSYQRRWLRSQT

FNIP2

261

Q9P278
TAALTSWAQAIFSTS

EEF1AKMT2

216

Q5JPI9
LKSNFLSYRSTWTST

CCDC78

416

A2IDD5
TTAAELSYSLRGNWS

MANBA

16

O00462
SLSSYAGSSLDVWRA

DOK7

351

Q18PE1
QASDWSRYSSSLLES

FAM171B

616

Q6P995
IRYNHTSQTSWTSSS

nan

61

A6NNC1
WTSSSTKRNAISSSY

nan

71

A6NNC1
YRTSSLWNSSQSTSS

MTERF3

61

Q96E29
STSNIFDTYSSWNIL

TAS2R40

266

P59535
TNWAIASGSSTALLY

TRIM33

416

Q9UPN9
RTFYNASWSSRATSP

PLA2G3

276

Q9NZ20
QRSTSLESWLTSYKS

AKAP6

1591

Q13023
SNSLLSSNCSTWKYF

CLEC9A

216

Q6UXN8
GKQWSSSSRSSYSSQ

PITPNM1

306

O00562
TSASLVSLAWTLASY

XKR7

266

Q5GH72
NSSSKISSEFTYAWS

CD96

166

P40200
YTSLASSANSSRWSL

TDRP

146

Q86YL5
RSSKGSSLSSESSWY

TIAM2

236

Q8IVF5
SSASFVSNTSRWTAA

STPG1

286

Q5TH74
WYSSSSSRSASRSYS

SRRM4

536

A7MD48
NLTSSSHTLTYSYWT

NPTN

171

Q9Y639
GSASTSLSYDSRWTV

PHF19

456

Q5T6S3
SLWSASRRFNSQSTS

MRPL21

31

Q7Z2W9
SALTWSLSSYTCATR

SLC66A3

146

Q8N755
RGYTASSLDSSSSWR

TASOR2

2056

Q5VWN6
QWSFSTISSSTQRSY

TMEM134

91

Q9H6X4
WSRTSSLFDIYSSDS

THAP10

216

Q9P2Z0
STTSVASSWYNRNNL

TTLL4

296

Q14679
TSQVTSLSSWTGYLL

ZNF554

106

Q86TJ5