Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 DNAH7 KIF2B KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

6.43e-10701289GO:0003777
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.07e-09181286GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH7 FRRS1L DNAH5 DNAH6 DNAH9 DNAH11

3.31e-09371287GO:0045505
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.07e-08281286GO:0051959
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH10 DNAH7 KIF2B KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

6.83e-081181289GO:0003774
GeneOntologyMolecularFunctionATP-dependent activity

RAD51C ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 KIF2B DQX1 UBA6 KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

4.07e-0761412817GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 KIF2B DQX1 KIF18B DNAH5 DNAH6 DNAH9 DNAH11

9.41e-0744112814GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 CILP2 GSPT2 KIF2B DQX1 GNA12 KIF18B DNAH5 DNAH6 DNAH9 DNAH11

2.61e-0583912817GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 CILP2 GSPT2 KIF2B DQX1 GNA12 KIF18B DNAH5 DNAH6 DNAH9 DNAH11

2.65e-0584012817GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 CILP2 GSPT2 KIF2B DQX1 GNA12 KIF18B DNAH5 DNAH6 DNAH9 DNAH11

2.65e-0584012817GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ERCC2 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 GSPT2 KIF2B DQX1 GNA12 KIF18B DNAH5 DNAH6 DNAH9 DNAH11

3.68e-0577512816GO:0017111
GeneOntologyMolecularFunctionglycolipid mannosyltransferase activity

PIGV ALG2

4.03e-0451282GO:0004376
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3R6 PIK3CG ATM

6.01e-04261283GO:0052742
GeneOntologyMolecularFunctionSUMO polymer binding

GCNA RNF111

6.01e-0461282GO:0032184
GeneOntologyMolecularFunction1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PIK3R6 PIK3CG

8.38e-0471282GO:0046934
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH10 TTLL8 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

5.83e-062101269GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH10 TTLL8 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

7.05e-062151269GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH10 TTLL8 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

7.05e-062151269GO:0001539
GeneOntologyBiologicalProcessmicrotubule-based movement

CLUAP1 DNAH10 TTLL8 DNAH7 SLC9C1 KIF2B NME5 KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

1.04e-0549312613GO:0007018
GeneOntologyBiologicalProcesscilium movement

DNAH10 TTLL8 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

3.29e-052611269GO:0003341
GeneOntologyBiologicalProcessmicrotubule-based process

CLUAP1 CDC42BPA DNAH10 TTLL8 DNAH7 SLC9C1 KIF2B ARHGEF1 MARK4 NME5 ATXN3 CEP152 KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

7.68e-05105812618GO:0007017
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9

4.14e-07251305GO:0005858
GeneOntologyCellularComponentmicrotubule associated complex

DNAH10 DNAH7 KIF2B KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

7.57e-071611309GO:0005875
GeneOntologyCellularComponentdynein complex

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.04e-06541306GO:0030286
GeneOntologyCellularComponentaxoneme

EFCAB6 DNAH10 TTLL8 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

6.02e-062071309GO:0005930
GeneOntologyCellularComponentciliary plasm

EFCAB6 DNAH10 TTLL8 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

6.26e-062081309GO:0097014
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH7 DNAH6

2.73e-05101303GO:0036156
GeneOntologyCellularComponent9+2 motile cilium

DNAH10 TTLL8 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.24e-042381308GO:0097729
GeneOntologyCellularComponentmicrotubule

EFCAB6 DNAH10 TTLL8 DNAH7 KIF2B SVIL KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

1.26e-0453313012GO:0005874
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

EFCAB6 DNAH10 TTLL8 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.67e-043171309GO:0032838
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class IB

PIK3R6 PIK3CG

2.28e-0441302GO:0005944
GeneOntologyCellularComponentmotile cilium

DNAH10 TTLL8 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

3.86e-043551309GO:0031514
GeneOntologyCellularComponentcytoplasmic region

EFCAB6 DNAH10 TTLL8 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

4.27e-043601309GO:0099568
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

5.66e-0461302GO:0097728
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class I

PIK3R6 PIK3CG

1.34e-0391302GO:0097651
GeneOntologyCellularComponentjunctional membrane complex

BAG5 RYR1

1.34e-0391302GO:0030314
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class IA

PIK3R6 PIK3CG

1.34e-0391302GO:0005943
GeneOntologyCellularComponentcilium

CLUAP1 EFCAB6 DNAH10 MYRIP PEX6 TTLL8 DNAH7 SLC9C1 MARK4 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.42e-0389813014GO:0005929
GeneOntologyCellularComponentMCM complex

MCM6 TONSL

2.03e-03111302GO:0042555
MousePhenovascular ring

PIGV SLIT2 LRP2 DNAH5 DNAH11

5.36e-06351035MP:0010466
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286IPR013602
DomainDHC_N2

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286PF08393
DomainMT

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286PF12777
DomainAAA_8

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.64e-10141286PF12780
DomainDHC_fam

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

4.38e-10151286IPR026983
DomainDynein_heavy

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

4.38e-10151286PF03028
DomainDynein_heavy_dom

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

4.38e-10151286IPR004273
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH5 DNAH6 DNAH9 DNAH11

2.66e-08141285IPR011704
DomainAAA_5

DNAH10 DNAH5 DNAH6 DNAH9 DNAH11

2.66e-08141285PF07728
DomainDHC_N1

DNAH10 DNAH5 DNAH9 DNAH11

1.44e-0781284PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH5 DNAH9 DNAH11

1.44e-0781284IPR013594
DomainP-loop_NTPase

RAD51C ERCC2 SAMD9 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 NLRP6 GSPT2 KIF2B DQX1 GNA12 KIF18B DNAH5 DNAH6 DNAH9 KIF11 DNAH11

1.28e-0684812820IPR027417
DomainAAA

RAD51C DNAH10 PEX6 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

6.74e-061441288SM00382
DomainAAA+_ATPase

RAD51C DNAH10 PEX6 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

6.74e-061441288IPR003593
Domain-

RAD51C ERCC2 SAMD9 DNAH10 DDX60 PEX6 MCM6 CHD2 DNAH7 GSPT2 DQX1 GNA12 DNAH5 DNAH6 DNAH9 DNAH11

5.15e-05746128163.40.50.300
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

2.25e-0827966M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

4.24e-0743966M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

5.60e-0745966M47670
PathwayPID_TXA2PATHWAY

TBXA2R PIK3R6 PIK3CG ARHGEF1 GNA12

3.83e-0556965M99
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH7 DNAH5 DNAH6 DNAH11

1.42e-091413259373155
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH10 DNAH6 DNAH9

2.13e-074132311175280
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERCC2 CDC42BPA KMT2B ANKRD37 UBR4 PEX6 RYR1 ARHGEF10L TYK2 PIM3 TNRC18 KANSL1 MARK4 TIGD3 GNA12 HAS3 DMWD GCN1

2.15e-0711051321835748872
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH9 DNAH11

5.31e-075132326909801
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH9 DNAH11

1.06e-066132333347437
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

WBP11 SAMD9 RBL1 PEX6 FAM111B TYK2 ARNT ARHGEF1 MCU TONSL LRCH4 ILVBL MGRN1

1.27e-066501321338777146
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH9 DNAH11

1.85e-067132331178125
Pubmed

Human transcription factor protein interaction networks.

SIN3B WBP11 CDC42BPA KMT2B DNAH10 UBR4 BAG5 TLX3 ARNT PBRM1 KANSL1 COX5A MRPS24 SVIL BRD7 LRP2 ZNF770 CEP152 ILVBL

2.03e-0614291321935140242
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

SIN3B DNAH7 PBRM1 BRD7 DNAH9

1.02e-0575132525593309
Pubmed

Photoreceptor Cell-Derived CAPN5 Regulates Retinal Pigment Epithelium Cell Proliferation Through Direct Regulation of SLIT2 Cleavage.

SLIT2 CAPN5

1.43e-052132229610848
Pubmed

Protein kinase D regulates the human cardiac L-type voltage-gated calcium channel through serine 1884.

CACNA1C PRKD1

1.43e-052132222100296
Pubmed

Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.

PIK3R6 PIK3CG

1.43e-052132221996737
Pubmed

PI3Kgamma adaptor subunits define coupling to degranulation and cell motility by distinct PtdIns(3,4,5)P3 pools in mast cells.

PIK3R6 PIK3CG

1.43e-052132219509406
Pubmed

Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.

DNAH10 DNAH6

1.43e-052132215937072
Pubmed

Isoproterenol-induced hypertrophy of neonatal cardiac myocytes and H9c2 cell is dependent on TRPC3-regulated CaV1.2 expression.

CACNA1C TRPC3

1.43e-052132233069962
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

1.43e-052132232357925
Pubmed

Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice.

CACNA1C TRPC3

1.43e-052132227522668
Pubmed

TRPC3-interacting triadic proteins in skeletal muscle.

TRPC3 RYR1

1.43e-052132218215135
Pubmed

p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.

PIK3R6 PIK3CG

1.43e-052132225753393
Pubmed

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

ARHGEF1 GNA12

1.43e-052132211313914
Pubmed

Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio.

PIK3R6 PIK3CG

1.43e-052132212707323
Pubmed

Some mutations in the xeroderma pigmentosum D gene may lead to moderate but significant radiosensitivity associated with a delayed radiation-induced ATM nuclear localization.

ERCC2 ATM

1.43e-052132231738647
Pubmed

Genetic enhancement of behavioral itch responses in mice lacking phosphoinositide 3-kinase-γ (PI3Kγ).

PIK3R6 PIK3CG

1.43e-052132222168443
Pubmed

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).

PIK3R6 PIK3CG

1.43e-052132224190998
Pubmed

Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins.

TRPC3 RYR1

1.43e-052132216484216
Pubmed

Ryanodine receptor activation by Ca v 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression.

CACNA1C RYR1

1.43e-052132218927079
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

1.43e-052132219410201
Pubmed

Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.

TBXA2R PIK3CG

1.43e-052132212796499
Pubmed

Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.

PIK3R6 PIK3CG

1.43e-052132219906996
Pubmed

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.

DNAH10 UBR4 BAG5 SVIL ILVBL

1.48e-0581132532060556
Pubmed

Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.

DNAH5 DNAH6 DNAH9

1.49e-0513132335942101
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SIN3B KMT2B UBR4 CHD2 AGPS RYR1 DQX1 FBXO43 LRP2 ATM RBM41 SPDYE16

2.55e-057361321229676528
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PIGV SLIT2 LRP2 DNAH5 DNAH11

4.12e-05100132525807483
Pubmed

Function, Regulation and Biological Roles of PI3Kγ Variants.

PIK3R6 PIK3CG

4.28e-053132231480354
Pubmed

Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors.

ARHGEF1 GNA12

4.28e-053132218320579
Pubmed

Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma.

PIK3R6 PIK3CG

4.28e-053132215611065
Pubmed

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence.

PBRM1 BRD7

4.28e-053132220660729
Pubmed

Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.

CACNA1C RYR1

4.28e-053132211206130
Pubmed

PI3K-like kinases restrain Pim gene expression in endothelial cells.

PIM3 ATM

4.28e-053132222282239
Pubmed

The regulatory subunits of PI3Kγ control distinct neutrophil responses.

PIK3R6 PIK3CG

4.28e-053132225605974
Pubmed

Monogenic and polygenic determinants of sarcoma risk: an international genetic study.

ERCC2 ATM

4.28e-053132227498913
Pubmed

Phosphatidylinositol-3-kinase-gamma is integral to homing functions of progenitor cells.

PIK3R6 PIK3CG

4.28e-053132218323525
Pubmed

Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity.

ATXN3 MGRN1

4.28e-053132224769000
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAH5 DNAH6

4.28e-053132226918822
Pubmed

PI3Kgamma (PI3Kgamma) is essential for efficient induction of CXCR3 on activated T cells.

PIK3R6 PIK3CG

4.28e-053132218658026
Pubmed

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.

PIK3R6 PIK3CG

4.28e-053132215797027
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAH5 DNAH9

4.28e-053132215750039
Pubmed

Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils.

PIK3R6 PIK3CG

4.28e-053132233144519
Pubmed

Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule.

TBXA2R ARHGEF1

4.28e-053132222086927
Pubmed

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits.

PIK3R6 PIK3CG

4.28e-053132210358071
Pubmed

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

DNAH5 DNAH9

4.28e-053132215845866
Pubmed

Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.

PIK3R6 PIK3CG

4.28e-053132221665146
Pubmed

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels.

PIK3R6 PIK3CG

4.28e-053132222930133
Pubmed

Whole-Exome Sequencing of Patients With Posterior Segment Uveitis.

TYK2 CAPN5

4.28e-053132232707200
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CACNA1C CDC42BPA PEPD MYRIP LAMA3 CHD2 SUCLA2 PPP4R4 TYK2 SPTBN4 TNRC18 SEMA3B UBA6 PRKD1 SPIDR BAIAP3 MGRN1

5.09e-0514891321728611215
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

DNAH10 PEPD PBRM1

6.76e-0521132322479202
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 EPX ARHGEF1 PRKD1 DNAH6 KIF11

8.33e-05187132626460568
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

8.54e-054132218492703
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAH5 DNAH9

8.54e-054132218950741
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

8.54e-054132236140829
Pubmed

Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.

PIK3R6 PIK3CG

8.54e-054132216476736
Pubmed

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets.

TBXA2R GNA12

8.54e-054132210037795
Pubmed

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli.

ATM IKBKB

8.54e-054132216497931
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1C WBP11 UBR4 MYRIP CHD2 EPX ALG2 PPP4R4 SPTBN4 TNRC18 GSPT2 GNA12 ATM DMWD DNAH6 KIF11

1.20e-0414421321635575683
Pubmed

A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.

PIK3R6 PIK3CG

1.42e-045132221393242
Pubmed

Loss of Function Genetic Screen Identifies ATM Kinase as a Positive Regulator of TLR3-Mediated NF-κB Activation.

ATM IKBKB

1.42e-045132232731169
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

1.42e-045132222499950
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH6

1.42e-045132239056782
Pubmed

Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.

ARHGEF1 GNA12

1.42e-045132227489999
Pubmed

Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptor gene.

RBL1 PIK3CG

1.42e-045132216943418
Pubmed

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.

DNAH5 DNAH9

1.42e-045132223849778
Pubmed

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout.

CACNA1C RYR1

1.42e-045132222355118
Pubmed

Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor.

ARHGEF1 GNA12

1.42e-045132210648409
Pubmed

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase.

PIK3R6 PIK3CG

1.42e-04513227624799
Pubmed

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.

PIK3R6 PIK3CG

1.42e-045132223824069
Pubmed

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.

DNAH5 DNAH9

1.42e-045132223525783
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DDX60 CHD2 RYR1 LRP2 DNAH5 KIF11

1.49e-04208132633230847
Pubmed

A protein interaction landscape of breast cancer.

RAD51C ERCC2 DDX60 UBR4 BAG5 RRP9 MCU SVIL BRD7 LRCH4

1.61e-046341321034591612
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TRAPPC11 UBR4 CHD2 DNAH7 RYR1 PPP4R4 PBRM1 COX5A MRPS24 DNAH11

1.69e-046381321031182584
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ERCC2 KMT2B MCM6 RYR1 IKBKB DNAH5

1.74e-04214132622199357
Pubmed

GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4.

PIK3R6 PIK3CG

2.12e-046132222728827
Pubmed

Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.

ERCC2 ATM

2.12e-046132220170971
Pubmed

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.

ATM IKBKB

2.12e-046132214966265
Pubmed

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation.

TIPARP ARNT

2.12e-046132223275542
Pubmed

Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress.

ATM IKBKB

2.12e-046132218583959
Pubmed

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.

ERCC2 ATM

2.12e-046132222537351
Pubmed

Identification of the MMS22L-TONSL complex that promotes homologous recombination.

MCM6 TONSL

2.97e-047132221055984
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH5 DNAH11

2.97e-04713229256245
Pubmed

RGS16 inhibits signalling through the G alpha 13-Rho axis.

ARHGEF1 GNA12

2.97e-047132214634662
Pubmed

Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells.

TBXA2R GNA12

2.97e-047132219772916
Pubmed

Constitutive knockout of Surf1 is associated with high embryonic lethality, mitochondrial disease and cytochrome c oxidase deficiency in mice.

COX5A SURF2

2.97e-047132212566387
Pubmed

Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma.

PIK3R6 PIK3CG

2.97e-047132212507995
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

ERCC2 BAG5 VPS50 AGPS SUCLA2 SLIT2 ARHGEF1 MCU PRKD1 ILVBL

3.02e-046861321028380382
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SIN3B WBP11 UBR4 SPTBN4 PBRM1 KCTD16 SVIL BRD7 UBA6 PRKD1 FRMPD3 KIF11

3.17e-049631321228671696
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

PBRM1 BRD7 LRP2

3.20e-0435132332504627
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TRAPPC11 ERCC2 UBR4 MCM6 AGPS SUCLA2 MRPS24 DNAH5 GCN1 KIF11

3.70e-047041321029955894
Pubmed

The transcription factor XBP1 is selectively required for eosinophil differentiation.

SIGLEC9 EPX ARNT

3.78e-0437132326147683
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF2B KIF18B KIF11

3.78e-0437132311416179
Pubmed

CHD7 cooperates with PBAF to control multipotent neural crest formation.

PBRM1 BRD7

3.94e-048132220130577
Pubmed

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells.

RRP9 SEMA3B

3.94e-048132211487633
GeneFamilyDyneins, axonemal

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.63e-1017916536
CoexpressionGSE45365_CD8A_DC_VS_CD11B_DC_UP

SAMD9 BAG5 AGPS PBRM1 GSPT2 MRPS24 MRPL32 KIF18B

6.94e-061971318M9997
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 ARMH4 DNAH11

4.24e-0918513195e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

3.92e-08169131814aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP4R4 FAM111B PIK3CG FBXO43 CEP152 KIF18B ZNF367 KIF11

4.29e-081711318c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH7 NME5 DNAH6 BAIAP3 DNAH9 ARMH4 DNAH11

8.23e-08186131885787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DNAH10 DNAH7 NME5 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

8.93e-0818813186833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.01e-0719113182a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.01e-07191131846c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.01e-071911318995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.01e-071911318a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.01e-0719113182d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellmulticiliated|World / shred by cell class for turbinate

DNAH10 ANKRD37 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.05e-0719213180f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.09e-071931318e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.14e-0719413181ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH10 DNAH7 SLC9C1 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.14e-071941318958e648138676d46698090b4046cb484083ae449
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.14e-0719413184a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.14e-071941318a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.18e-0719513180e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.18e-071951318581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.18e-07195131893b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 ARMH4 DNAH11

1.18e-0719513183486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 ARMH4 DNAH11

1.18e-071951318e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.23e-071961318de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.28e-07197131871fea4aa6ce96c7693fa94792d08770622873850
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CLUAP1 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.33e-071981318ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH7 NME5 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.44e-07200131852aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH7 NME5 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.44e-07200131855c148238d5c80c1faa3428a917ae8075be2c145
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.44e-0720013186a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CLUAP1 DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.44e-0720013188dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

3.29e-0715113178216462e723fec2797387929dde095370947e10a
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 CIB4 NME5 DNAH5 DNAH6 DNAH9 DNAH11

9.23e-071761317ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

EFCAB6 DNAH10 DNAH7 DNAH6 BAIAP3 DNAH9 DNAH11

9.95e-071781317255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

9.95e-071781317d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 CIB4 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.03e-061791317d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 CIB4 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.03e-0617913178a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.03e-0617913175e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 MCM6 FAM111B TONSL KIF18B ZNF367 KIF11

1.03e-06179131788d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.07e-0618013171f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.11e-061811317dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.15e-061821317fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.20e-061831317b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.20e-061831317cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 DNAH10 MELTF LRP2 DNAH5 DNAH9 DNAH11

1.24e-0618413172cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 DNAH10 MELTF LRP2 DNAH5 DNAH9 DNAH11

1.24e-061841317ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB6 DNAH10 MELTF LRP2 DNAH5 DNAH9 DNAH11

1.24e-0618413172b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.24e-06184131707c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FAM111B FBXO43 CEP152 KIF18B ZNF367 KIF11

1.29e-06185131730e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.29e-06185131718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

EFCAB6 DNAH10 DNAH7 NME5 DNAH6 DNAH9 DNAH11

1.34e-061861317f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.34e-06186131776033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.38e-0618713172b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.38e-0618713179e10ed56090d82589bc457788282f664b70ace4b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FAM111B FBXO43 CEP152 KIF18B ZNF367 KIF11

1.38e-0618713179351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.43e-061881317803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.43e-06188131782c006f43c93f4a867953a446864f02b44536a23
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.43e-061881317da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.43e-0618813179a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EFCAB6 DNAH10 DNAH7 NME5 DNAH6 DNAH9 DNAH11

1.49e-06189131768a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 BAIAP3 DNAH9

1.49e-061891317b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellMulticiliated|World / shred by cell class for nasal brushing

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.49e-06189131734b110aef839376228c5a403a6b5047a945f472b
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.49e-06189131727329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.49e-0618913173e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated|World / shred by cell class for parenchyma

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.49e-061891317711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.54e-0619013179ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.54e-061901317833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.54e-0619013177031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH7 DNAH5 DNAH6 BAIAP3 DNAH9 DNAH11

1.54e-061901317cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-0619113177b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH10 DNAH7 NME5 DNAH6 BAIAP3 DNAH9

1.59e-061911317683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-061911317fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 BAIAP3 DNAH9 DNAH11

1.59e-061911317ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

RBL1 FAM111B FBXO43 CEP152 KIF18B ZNF367 KIF11

1.59e-061911317bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-061911317b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-061911317c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-061911317e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-0619113179d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-061911317cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 BAIAP3 DNAH9 DNAH11

1.59e-0619113176228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.59e-0619113171c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.65e-061921317097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.65e-061921317be592e661367affced9ebe80849b466e6adb3a34
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.65e-061921317d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.65e-061921317354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.71e-0619313173e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.71e-0619313170e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.71e-061931317aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

EFCAB6 DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 DNAH11

1.71e-061931317ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.71e-0619313170b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CLUAP1 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.77e-061941317b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CLUAP1 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.77e-0619413177a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.77e-06194131743be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-061951317d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-061951317649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-06195131734e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-061951317129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-0619513173e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-0619513179651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-06195131707a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.83e-061951317e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DNAH7 DNAH5 DNAH6 DNAH9 ARMH4 DNAH11

1.89e-06196131727b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH7 NME5 DNAH5 DNAH6 DNAH9 DNAH11

1.89e-061961317009e83c7251cf300be78b263634d233a8d972a68
Diseasevisceral heterotaxy (implicated_via_orthology)

SLIT2 COX5A DNAH5 DNAH11

1.94e-05371274DOID:0050545 (implicated_via_orthology)
DiseaseKartagener syndrome (implicated_via_orthology)

SLIT2 DNAH5 DNAH11

2.74e-05141273DOID:0050144 (implicated_via_orthology)
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

SLIT2 NME5 DNAH5

7.17e-05191273DOID:9562 (implicated_via_orthology)
DiseaseSkin Ulcer

PEPD LAMA3

1.10e-0441272C0037299
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

1.10e-0441272DOID:0050144 (is_implicated_in)
Diseaselung small cell carcinoma (is_implicated_in)

LAMA3 PBRM1 ATM

2.36e-04281273DOID:5409 (is_implicated_in)
Diseaseprimary ciliary dyskinesia (is_implicated_in)

DNAH7 NME5

2.73e-0461272DOID:9562 (is_implicated_in)
Diseasedisease of cellular proliferation (implicated_via_orthology)

TYK2 ATM

3.81e-0471272DOID:14566 (implicated_via_orthology)
DiseaseInfection

SAMD9 PEPD

3.81e-0471272C3714514
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

RYR1 FAM111B SPTBN4 PBRM1 ATM

4.61e-041481275C0279702
DiseaseDystonia

KMT2B SUCLA2 SUOX ATM

5.29e-04861274C0013421
Diseaseapolipoprotein B measurement

ERCC2 DNAH10 APOA5 PEX6 PPP4R4 CILP2 MARK4 B4GALNT3 DMWD DNAH11

6.08e-0466312710EFO_0004615
Diseasebrain measurement, neuroimaging measurement

SLIT2 PBRM1 KANSL1 ARHGEF1 LRCH4 GNA12 MRPL32 HAS3 DNAH11

6.45e-045501279EFO_0004346, EFO_0004464
Diseaseneuroimaging measurement

SAMD9 CDC42BPA KMT2B TYK2 SLIT2 KANSL1 ARHGEF1 LRCH4 GNA12 MRPL32 ARHGAP27 KIF18B DNAH11

7.23e-04106912713EFO_0004346
Diseasesenile cataract (is_implicated_in)

ERCC2 ATM

9.86e-04111272DOID:9669 (is_implicated_in)
Diseaseovarian carcinoma, COVID-19

KANSL1 ARHGAP27

9.86e-04111272EFO_0001075, MONDO_0100096
DiseasePrimary Ciliary Dyskinesia

DNAH5 DNAH9 DNAH11

1.10e-03471273C4551720
Diseaseadvanced glycosylation end product-specific receptor, soluble measurement

KANSL1 B4GALNT3

1.39e-03131272EFO_0020131
Diseasefacial morphology

KIF2B LGI2 MCU

1.73e-03551273EFO_0004743
Diseaseretinal vasculature measurement

CACNA1C CDC42BPA MCM6 CAPN5 HAS3 DNAH5 DNAH9 ZNF367

1.83e-035171278EFO_0010554
Diseasebody fat distribution

GPR78 CILP2 PBRM1 GNA12 B4GALNT3

1.85e-032021275EFO_0004341
DiseaseBMI-adjusted adiponectin measurement

PEPD PBRM1

1.86e-03151272EFO_0007737
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERCC2 ATM

1.86e-03151272C0496930
DiseaseSitus ambiguus

DNAH5 DNAH9

1.86e-03151272C0266642
DiseaseBenign neoplasm of bladder

ERCC2 ATM

1.86e-03151272C0154017
DiseaseCarcinoma in situ of bladder

ERCC2 ATM

1.86e-03151272C0154091
Diseaseresponse to olanzapine

CACNA1C CIB4

1.86e-03151272GO_0097333
DiseaseBMI-adjusted waist circumference, physical activity measurement

DNAH10 PEPD PBRM1 GNA12

2.00e-031231274EFO_0007789, EFO_0008002
Diseasediacylglycerol 44:7 measurement

NRBP1 APOA5

2.12e-03161272EFO_0020069
DiseaseSarcomatoid Renal Cell Carcinoma

RYR1 FAM111B SPTBN4 PBRM1

2.31e-031281274C1266043
DiseaseChromophobe Renal Cell Carcinoma

RYR1 FAM111B SPTBN4 PBRM1

2.31e-031281274C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

RYR1 FAM111B SPTBN4 PBRM1

2.31e-031281274C1266044
DiseasePapillary Renal Cell Carcinoma

RYR1 FAM111B SPTBN4 PBRM1

2.31e-031281274C1306837
DiseaseRenal Cell Carcinoma

RYR1 FAM111B SPTBN4 PBRM1

2.31e-031281274C0007134
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

DNAH10 MCM6

2.40e-03171272EFO_0004611, EFO_0007800
DiseaseCarcinoma of bladder

ERCC2 ATM

2.69e-03181272C0699885
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

DNAH10 PEPD PBRM1

3.32e-03691273EFO_0007788, EFO_0008002
DiseaseNonorganic psychosis

CACNA1C PBRM1 GNA12

3.32e-03691273C0349204
Diseaseacetate measurement

MCM6 DUSP29

3.32e-03201272EFO_0010112
Diseasetriglyceride measurement, body fat percentage

DNAH10 PEPD

3.66e-03211272EFO_0004530, EFO_0007800
DiseaseBronchiectasis

DNAH5 DNAH11

4.01e-03221272C0006267
Diseaseintellectual disability (implicated_via_orthology)

RBL1 UBR4 KANSL1

4.20e-03751273DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PVSVNRLSFVRNRCR

ARNT

276

P27540
LRKRFCRAQAPSSTI

ADGRF3

1031

Q8IZF5
QEAESRPRCRRLQLK

ARHGEF1

541

Q92888
EFLKRRQVCSPDRVT

ARHGEF10L

436

Q9HCE6
TITRTLCEQAPKRRA

CEP152

1401

O94986
SLEKNPCIREARRRA

BAG5

321

Q9UL15
VLRQVQVCPSFRRRT

BAIAP3

46

O94812
RRLVNSQCEFERRKP

BRD7

331

Q9NPI1
RRQVLNTRAQEPKLC

B4GALNT3

761

Q6L9W6
VATQCLAFPKIERRR

ARMH4

21

Q86TY3
SRRLKQPKAFCLRDV

MIR22HG

41

Q0VDD5
TLRVRARKFPAIVNC

DNAH11

2991

Q96DT5
PARLSRCVQVLSRKL

APOA5

221

Q6Q788
VLICIQQRPKRSTRR

CAPN5

401

O15484
CRRGSQRSIDLNKPI

DMWD

141

Q09019
PDRNDCVAVLRQKRS

ANKRD37

131

Q7Z713
LQIIRRECLTNKPRY

RAD51C

61

O43502
CLPQRFAKSKQLTRR

RBM41

136

Q96IZ5
NRQRLCERLRKNPAV

PEPD

26

P12955
RREIKRRPLFRSCFI

TIPARP

396

Q7Z3E1
LVRLDFSCNRVSRIP

LRCH4

206

O75427
RNPVCANRRRFLLDT

MCM6

181

Q14566
RLLCELFIRAPKRRN

PBRM1

66

Q86U86
ASAQKLVRPIRAVCR

HRURF

6

P0DUH7
RRLLRTCVDFFRLVP

LETM2

166

Q2VYF4
KIPNNCSGVRRRRLS

PRKD1

191

Q15139
ISVRLPSRRERCQFT

MCU

86

Q8NE86
FNLNTTEVEPCRRRK

LAMA3

2581

Q16787
IAIKQCRQELSPRNR

IKBKB

41

O14920
QADAKFRRVPRILVC

KCTD16

181

Q68DU8
VVVRCRPFNLAERKA

KIF11

21

P52732
CRLPFRALLQIRAVR

MGRN1

316

O60291
RLRIDPINERSFICN

ATXN3

101

P54252
RCQFDEKSRDPRVLR

DDX60

516

Q8IY21
TRPRFVKQDQVCIAR

GSPT2

571

Q8IYD1
RTITGRCNNKRRPLL

EPX

146

P11678
LQAIFSRARRCRPAV

PEX6

511

Q13608
IVQRRKLRLSPEQCS

NME5

41

P56597
VLSCKKRRLVRPNSI

KANSL1

596

Q7Z3B3
LAQRVCIQRKPLRFC

ERCC2

361

P18074
CLLVRIVFPSRAKRQ

GCN1

121

Q92616
LQRKSARRCVKQRPS

KMT2B

1071

Q9UMN6
QRPKIERSFLDCTNR

LRP2

2211

P98164
NLRRCPRLTAAQRIA

MSLNL

201

Q96KJ4
HPSVRQRCLIQQKRR

GPR78

221

Q96P69
GTKRQRQSFLPCLRR

KIF18B

646

Q86Y91
LRPISKCQAEARRLR

DQX1

361

Q8TE96
REFIQKCLQSEPARR

NRBP1

301

Q9UHY1
NRSERCPRDTRIVQL

P2RY13

31

Q9BPV8
KCLPRRRLNVSFALL

FBXO43

151

Q4G163
FVAVRLCRRSRAAPV

PCDHB7

706

Q9Y5E2
AANRIICTIRSRRPQ

ATM

2601

Q13315
QRCLRTILKRFFSPE

DNAH6

3761

Q9C0G6
CKTVRLSDVRVRPVN

GPR135

301

Q8IZ08
PLCKFCVSVRRVRDI

ILVBL

171

A1L0T0
QRQCVEYALKARPLR

CACNA1C

1206

Q13936
RCVLPNRGFLKQLRE

DUSP29

181

Q68J44
LVRPQELRRVLETFC

EFCAB6

191

Q5THR3
RECKALKQRPRFVAL

CHD2

456

O14647
LRASCRRVANVDKSP

FRMPD3

1671

Q5JV73
VFENNRVTCRFKRPV

FRRS1L

196

Q9P0K9
RVTCRFKRPVNVPRD

FRRS1L

201

Q9P0K9
AFRNRLRKFPALVNC

DNAH7

2481

Q8WXX0
FRNPKASLRVRLCDL

CARD19

51

Q96LW7
LVQCFDRKRRNRSKP

GNA12

331

Q03113
NFILKRRRCIALVVE

CRYM-AS1

16

A6NIL9
ILRRFLVLNPAKRCT

MARK4

286

Q96L34
VQKPRRARQKLRCLS

LCE6A

51

A0A183
SVARRAPKRQASCIL

GCNA

36

Q96QF7
LRKCLRSAQRISFPD

HAS3

101

O00219
KLRVRSRKFPAIVNC

DNAH9

2961

Q9NYC9
CSLPRKYRQINSQVR

FAM111B

351

Q6SJ93
PKIIDAALRACRRLN

COX5A

86

P20674
RVCRVVNLRTLFKEN

DNAH10

401

Q8IVF4
PFQKLLILRCFRVDR

DNAH10

3826

Q8IVF4
KRLAVFAQPIVSRAR

RYR1

3336

P21817
KQRRRAVVACFRMTP

RYR1

3626

P21817
QALCRFPELALQRVR

NLRP6

636

P59044
LLEFQNRCRKLPRAL

DNAH5

1446

Q8TE73
VCVRKRPLNQRETTL

KIF2B

216

Q8N4N8
ERIFLCQGKRPRSQE

MCAM

111

P43121
SPVCAKNRAARVRVS

MRPS24

31

Q96EL2
QLNDFCKPRSVRRIT

SERGEF

41

Q9UGK8
TIEVNRCRRRNPQKL

MRPL32

86

Q9BYC8
PVQKAASRTLCIFLR

PPP4R4

541

Q6NUP7
FNCKESPRINLRKVR

SLC9C1

1161

Q4G0N8
FRRQRLKPEIQCVSA

MELTF

386

P08582
NACRRPELKSRVERS

SVIL

606

O95425
ACLIPRSAQVRRLAR

LGI2

21

Q8N0V4
RKQRRIPCSVKDLFN

RBL1

161

P28749
SKFSEPLQVERCRRN

SAMD9

1321

Q5K651
PLQVERCRRNLVALK

SAMD9

1326

Q5K651
RLRKRETQKFCLTPR

PIK3R6

436

Q5UE93
ERSRVPRFVQQCIRA

ARHGAP27

706

Q6ZUM4
IFVVVRSCRKKSARP

SIGLEC9

366

Q9Y336
YRRGTLCRAKQVQPL

SIN3B

1076

O75182
PSLRLQTDARKVRCI

SURF2

16

Q15527
RKDIPCIFRVTASQL

CDC42BPA

1156

Q5VT25
ICNQVLVCERKYPRR

SUCLA2

151

Q9P2R7
QVSACIPVFRLARRR

ALG2

116

Q9H553
REIAKQRCAPASIRL

AGPS

406

O00116
LRVNPFRDRICRVFS

CIB4

61

A0PJX0
LFNLDVPERRRCFVK

CILP2

726

Q8IUL8
AKIRANLVCRRSTDP

nan

6

Q8IZM0
RNRKRLETLQSVRPC

CLUAP1

226

Q96AJ1
FISCSAVRVKPNRRA

PRDM10-DT

6

Q96N53
YKQPVVLREDNCRRR

PIK3CG

6

P48736
PSRKEVLRFAVSCRI

PIGV

6

Q9NUD9
RKQPFCLLLREAEAR

TNRC18

1796

O15417
AVLTRRKSNVIRKPC

ZBTB48

251

P10074
FNRRLNEVSKRVRIP

VPS50

826

Q96JG6
RRFQVSQPQISRICK

TIGD3

36

Q6B0B8
GCFQVIKLLSRRPRN

UBA6

681

A0AVT1
SRACLRIRKRIFNNP

TRMO

56

Q9BU70
RRARRQVLPVCNLKA

TTLL8

606

A6PVC2
CANRRADRVPISFKV

TRAPPC11

41

Q7Z392
SLRRLPCRKRFVKNN

RNF111

206

Q6ZNA4
RIKEARNSVCIIPLR

RRP9

451

O43818
SRPQCRVKVKLLQRS

SPIDR

841

Q14159
CTRFQPSAKRRFRRQ

SEMA3B

541

Q13214
IPLVRNRRFQLCRCM

SPDYE16

241

A6NNV3
RPRARAKQVRLTCMQ

TONSL

871

Q96HA7
IQSKLRACNRRLFVP

SPTBN4

376

Q9H254
PGFQTEQIRKRLRCR

PROKR2

256

Q8NFJ6
RCTSPRRLANKRIGQ

SLIT2

456

O94813
LLFRRRVSPECQQLI

PIM3

256

Q86V86
RKKPRTSFSRVQICE

TLX3

166

O43711
FSVPRENIRTRHKIC

ZNF770

461

Q6IQ21
RLQQACRLKSIPSRI

SUOX

11

P51687
CFRPTNITLEERRLI

TBXA2R

11

P21731
PICRLRFTEANTLRR

ZNF524

201

Q96C55
TRFVPTALRVRRENK

WBP11

576

Q9Y2W2
RIRCNICNRVFPREK

ZNF367

166

Q7RTV3
SCKQALIRVLRPRNK

UBR4

2696

Q5T4S7
IVNFPKCRRRRLQKD

TRPC3

711

Q13507
FKDCIPRSFRRHIRQ

TYK2

211

P29597
QVRRTPAQCRRRYKF

UTF1

106

Q5T230
NIAPCVRFTRRRDQK

MYRIP

771

Q8NFW9