Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase III general transcription initiation factor binding

BDP1 ZBTB43

1.20e-044902GO:0001025
GeneOntologyMolecularFunctionToll-like receptor 2 binding

TLR1 TLR6

1.20e-044902GO:0035663
GeneOntologyMolecularFunctioncupric ion binding

MUC2 PRNP

1.99e-045902GO:1903135
GeneOntologyMolecularFunctioncuprous ion binding

MUC2 PRNP

7.09e-049902GO:1903136
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing N-glycosyl compounds

TLR1 NEIL3 TLR6

8.34e-0441903GO:0016799
GeneOntologyMolecularFunctionlipopeptide binding

TLR1 TLR6

8.83e-0410902GO:0071723
HumanPhenoHypoplasia of deltoid muscle

SALL4 TBX5

3.58e-052312HP:0030241
HumanPhenoAplasia of metacarpal bones

TRIO SALL4 TBX5

4.33e-0512313HP:0010048
HumanPhenoAplasia/Hypoplasia of the 1st metacarpal

TRIO RTL1 SALL4 TBX5

4.58e-0534314HP:0010026
HumanPhenoAplasia/Hypoplasia of the proximal phalanges of the hand

TRIO RTL1 SALL4 TBX5

7.96e-0539314HP:0009851
HumanPhenoAbnormal 1st metacarpal morphology

TRIO RTL1 SALL4 TBX5

8.81e-0540314HP:0010009
DomainZINC_FINGER_C2H2_2

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF280B ZNF221 ZNF112 ZNF551 ZNF687

8.40e-057759013PS50157
DomainZINC_FINGER_C2H2_1

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF280B ZNF221 ZNF112 ZNF551 ZNF687

8.62e-057779013PS00028
DomainZnf_C2H2-like

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF280B ZNF221 ZNF112 ZNF551 ZNF687

1.10e-047969013IPR015880
Domainzf-C2H2

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF221 ZNF112 ZNF551 ZNF687

1.20e-046939012PF00096
DomainZnf_C2H2

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF280B ZNF221 ZNF112 ZNF551 ZNF687

1.23e-048059013IPR007087
DomainZnF_C2H2

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF280B ZNF221 ZNF112 ZNF551 ZNF687

1.27e-048089013SM00355
DomainPTPc_motif

PTPDC1 PTPN13 PTPRE PTPN22

1.87e-0459904SM00404
DomainTyr_Pase_cat

PTPDC1 PTPN13 PTPRE PTPN22

1.87e-0459904IPR003595
DomainToll-like_receptor

TLR1 TLR6

2.27e-045902IPR017241
DomainSpectrin/alpha-actinin

AKAP6 TRIO DSP

4.85e-0432903IPR018159
DomainSPEC

AKAP6 TRIO DSP

4.85e-0432903SM00150
DomainZnf_C2H2/integrase_DNA-bd

RLF ZNF773 ZNF789 ZNF423 ZBTB43 ZFP14 SALL4 ZNF221 ZNF112 ZNF551 ZNF687

4.97e-046949011IPR013087
DomainPTPc

PTPN13 PTPRE PTPN22

6.89e-0436903SM00194
DomainTYR_PHOSPHATASE_1

PTPDC1 PTPN13 PTPRE PTPN22

7.92e-0486904PS00383
Domainzf-C2H2_11

ZNF592 ZNF687

8.09e-049902PF16622
DomainTYR_PHOSPHATASE_2

PTPDC1 PTPN13 PTPRE PTPN22

8.27e-0487904PS50056
DomainTYR_PHOSPHATASE_dom

PTPDC1 PTPN13 PTPRE PTPN22

8.27e-0487904IPR000387
DomainTYR_PHOSPHATASE_PTP

PTPN13 PTPRE PTPN22

8.72e-0439903PS50055
DomainPTPase_domain

PTPN13 PTPRE PTPN22

1.01e-0341903IPR000242
DomainY_phosphatase

PTPN13 PTPRE PTPN22

1.01e-0341903PF00102
Domain-

PTPDC1 PTPN13 PTPRE PTPN22

1.02e-03929043.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPDC1 PTPN13 PTPRE PTPN22

1.34e-0399904IPR029021
DomainTIL

FCGBP MUC2

1.47e-0312902PF01826
DomainC8

FCGBP MUC2

1.47e-0312902PF08742
Domain-

RLF ZNF773 ZNF789 ZNF423 ZBTB43 ZFP14 SALL4 ZNF221 ZNF112 ZNF551

1.57e-0367990103.30.160.60
DomainUnchr_dom_Cys-rich

FCGBP MUC2

1.73e-0313902IPR014853
DomainC8

FCGBP MUC2

1.73e-0313902SM00832
DomainTIL_dom

FCGBP MUC2

2.01e-0314902IPR002919
DomainVWD

FCGBP MUC2

2.64e-0316902SM00216
DomainVWF_type-D

FCGBP MUC2

2.64e-0316902IPR001846
DomainVWFD

FCGBP MUC2

2.64e-0316902PS51233
DomainVWD

FCGBP MUC2

2.64e-0316902PF00094
DomainTF_T-box

MGA TBX5

2.98e-0317902IPR001699
DomainTBOX

MGA TBX5

2.98e-0317902SM00425
DomainTF_T-box_CS

MGA TBX5

2.98e-0317902IPR018186
Domain-

MGA TBX5

2.98e-03179022.60.40.820
DomainTBOX_3

MGA TBX5

2.98e-0317902PS50252
DomainT-box

MGA TBX5

2.98e-0317902PF00907
DomainTBOX_1

MGA TBX5

2.98e-0317902PS01283
DomainTBOX_2

MGA TBX5

2.98e-0317902PS01264
DomainVWC_out

FCGBP MUC2

3.72e-0319902SM00215
DomainTIR

TLR1 TLR6

4.54e-0321902SM00255
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 PTPN13 TRIO ZNF592 DSP SGSM2 ZNF423 ZBTB43 TRIM8 NUP43 NBEA TNKS EIF3F TTC3 SMURF2

1.37e-061285921535914814
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RLF PTPN13 ZNF592 DSP CRYBG3 ANKHD1 MGA GOLGB1 ZNF687

1.73e-0641892934709266
Pubmed

Functional proteomics mapping of a human signaling pathway.

RLF PAPPA2 SMG1 ZNF592 EIF3F TTC3 CBLB MGA SMURF2 GOLGB1

3.85e-06591921015231748
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 TLK2 PTPN13 FECH OSBPL11 SALL4 ANKHD1 POLK CDCP1 TTC3 MGA ITGB4 GOLGB1

5.58e-061084921311544199
Pubmed

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

TLR1 TLR6

6.92e-06292222315281
Pubmed

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

TLR1 TLR6

6.92e-06292218036178
Pubmed

The quantification of hCLCA2 and colocalisation with integrin beta4 in stratified human epithelia.

CLCA2 ITGB4

6.92e-06292215707651
Pubmed

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

TLR1 TLR6

6.92e-06292224445834
Pubmed

[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].

TLR1 TLR6

6.92e-06292226470427
Pubmed

Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.

TLR1 TLR6

6.92e-06292221852947
Pubmed

Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).

TLR1 TLR6

6.92e-06292224984237
Pubmed

Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.

FCGBP MUC2

6.92e-06292219432394
Pubmed

Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance.

POLL POLK

6.92e-06292220164241
Pubmed

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.

TLR1 TLR6

6.92e-06292211123271
Pubmed

SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.

TLR1 TLR6

6.92e-06292225261617
Pubmed

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

TLR1 TLR6

6.92e-06292229175392
Pubmed

The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.

FCGBP MUC2

6.92e-06292234126068
Pubmed

The zinc finger protein ZNF297B interacts with BDP1, a subunit of TFIIIB.

BDP1 ZBTB43

6.92e-06292216542149
Pubmed

The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.

TLR1 TLR6

6.92e-06292228474755
Pubmed

Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression.

CNKSR2 SMURF2

6.92e-06292229534682
Pubmed

A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.

TLR1 TLR6

6.92e-06292222778390
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 SMG1 TRIO ZNF592 DSP TUBGCP3 TNKS TTC3 MGA

7.03e-0649792923414517
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RLF RAD52 BDP1 PTPDC1 PTPN13 PTPRE TRIO SGSM2 SDCCAG8 FECH WDR27 POLK TTC3 SMURF2 GOLGB1

8.17e-061489921528611215
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

SMG1 CCP110 SGSM2 ZBTB43

1.13e-05529249455477
Pubmed

The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis.

SALL4 TBX5

2.07e-05392231388035
Pubmed

Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.

TLR1 TLR6

2.07e-05392216081826
Pubmed

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.

TLR1 TLR6

2.07e-05392218752252
Pubmed

The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis.

CLCA2 ITGB4

2.07e-05392211320086
Pubmed

Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves' disease.

TLR1 TLR6

2.07e-05392225028161
Pubmed

Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs.

TLR1 TLR6

2.07e-05392215731092
Pubmed

Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.

TLR1 TLR6

2.07e-05392225246533
Pubmed

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.

TLR1 TLR6

2.07e-05392211095740
Pubmed

IFNs activate toll-like receptor gene expression in viral infections.

TLR1 TLR6

2.07e-05392211607792
Pubmed

[Association of polymorphisms in toll-like receptor genes with atopic dermatitis in the Republic of Bashkortostan].

TLR1 TLR6

2.07e-05392225850295
Pubmed

Ureaplasma parvum lipoproteins, including MB antigen, activate NF-{kappa}B through TLR1, TLR2 and TLR6.

TLR1 TLR6

2.07e-05392218451040
Pubmed

Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA.

POLL POLK

2.07e-05392211784855
Pubmed

TLR1- and TLR6-independent recognition of bacterial lipopeptides.

TLR1 TLR6

2.07e-05392216455646
Pubmed

Toll-like receptor polymorphisms are associated with increased neurosyphilis risk.

TLR1 TLR6

2.07e-05392224922103
Pubmed

Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.

TLR1 TLR6

2.07e-05392224683188
Pubmed

A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.

TLR1 TLR6

2.07e-05392216177110
Pubmed

Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis.

TLR1 TLR6

2.07e-05392222150367
Pubmed

Toll-like receptor 1, 2 and 6 polymorphisms: no association with 11 serum cytokine concentrations.

TLR1 TLR6

2.07e-05392230028533
Pubmed

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.

TLR1 TLR6

2.07e-05392219931471
Pubmed

Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

TLR1 TLR6

2.07e-05392223626692
Pubmed

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.

TLR1 TLR6

2.07e-05392215812078
Pubmed

Epistatic effect of TLR-1, -6 and -10 polymorphisms on organic dust-mediated cytokine response.

TLR1 TLR6

2.07e-05392228123183
Pubmed

Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.

TLR1 TLR6

2.07e-05392222822027
Pubmed

Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.

KIF21B NBEA

2.07e-05392229847800
Pubmed

The interacting binding domains of the beta(4) integrin and calcium-activated chloride channels (CLCAs) in metastasis.

CLCA2 ITGB4

2.07e-05392214512419
Pubmed

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

TLR1 TLR6

2.07e-05392224511099
Pubmed

Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease.

TLR1 TLR6

2.07e-05392218091991
Pubmed

TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation.

TLR1 TLR6

2.07e-05392216461792
Pubmed

Toll-like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette-Guérin osteitis following newborn vaccination.

TLR1 TLR6

2.07e-05392225605403
Pubmed

Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

TLR1 TLR6

2.07e-05392214966134
Pubmed

Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.

TLR1 TLR6

2.07e-05392217932345
Pubmed

Toll-like receptor 2 subfamily genotypes are not associated with severity of bronchiolitis or postbronchiolitis wheezing in infants.

TLR1 TLR6

2.07e-05392224112285
Pubmed

Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses.

TLR1 TLR6

2.07e-05392223151486
Pubmed

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.

TLR1 TLR6

2.07e-05392212077222
Pubmed

Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

TLR1 TLR6

2.07e-05392217595379
Pubmed

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

TLR1 TLR6

2.07e-05392218056480
Pubmed

Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases.

TLR1 TLR6

2.07e-05392216374251
Pubmed

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

TLR1 TLR6

2.07e-05392221998742
Pubmed

Soluble Toll-like receptor 1 family members in the amniotic fluid of women with preterm prelabor rupture of the membranes.

TLR1 TLR6

2.07e-05392222280448
Pubmed

Nephronophthisis-Related Ciliopathies

ZNF423 SDCCAG8 NPHP4

2.30e-052192327336129
Pubmed

Toll-like receptor heterodimer variants protect from childhood asthma.

TLR1 TLR6

4.14e-05492218547625
Pubmed

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.

TLR1 TLR6

4.14e-05492222198949
Pubmed

TTC3 contributes to TGF-β1-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation.

TTC3 SMURF2

4.14e-05492230696809
Pubmed

A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide.

TLR1 TLR6

4.14e-05492220478617
Pubmed

Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.

TLR1 TLR6

4.14e-05492211739528
Pubmed

Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.

FCGBP MUC2

4.14e-05492228604600
Pubmed

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf.

RLF CNKSR2

4.14e-05492214597674
Pubmed

Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.

TLR1 TLR6

4.14e-05492216622218
Pubmed

Association of Toll-like receptor polymorphisms with HIV status in North Americans.

TLR1 TLR6

4.14e-05492225253287
Pubmed

Racial variation in toll-like receptor variants among women with pelvic inflammatory disease.

TLR1 TLR6

4.14e-05492223255565
Pubmed

Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth.

CLCA2 ITGB4

4.14e-05492212110680
Pubmed

Polymorphisms in the toll-like receptor 2 subfamily and risk of asthma: a case-control analysis in a Chinese population.

TLR1 TLR6

4.14e-05492220815312
Pubmed

Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.

TLR1 TLR6

4.14e-05492220348427
Pubmed

Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa.

POLL POLK

4.14e-05492212509270
Pubmed

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

TLR1 TLR6

4.14e-05492224860120
Pubmed

Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.

KLK3 PZP

4.14e-0549221702714
Pubmed

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.

TLR1 TLR6

4.14e-05492211081518
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

AKAP6 TRIO NBEA TNKS CNKSR2

5.24e-0515192517043677
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KIF21B BDP1 KIAA0825 ZNF592 TOPAZ1 PTPN22 NBEA ZNF687

5.35e-0549792836774506
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF773 ZNF592 ZNF423 ZBTB43 SALL4 ZNF280B MGA UTY ZNF687 TBX5

5.62e-05808921020412781
Pubmed

The cellular prion protein identifies bipotential cardiomyogenic progenitors.

PRNP TBX5

6.89e-05592219910576
Pubmed

Association between toll-like receptors/CD14 gene polymorphisms and inflammatory bowel disease in Korean population.

TLR1 TLR6

6.89e-05592222219617
Pubmed

Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans.

TLR1 TLR6

6.89e-05592219771452
Pubmed

TLR6: A novel member of an expanding toll-like receptor family.

TLR1 TLR6

6.89e-05592210231569
Pubmed

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

TLR1 TLR6

6.89e-05592219362712
Pubmed

Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.

TLR1 TLR6

6.89e-05592224014382
Pubmed

Toll-like receptor gene polymorphisms confer susceptibility to graft-versus-host disease in allogenic hematopoietic stem cell transplantation.

TLR1 TLR6

6.89e-05592222703024
Pubmed

Association of MBL2, TLR1, TLR2 and TLR6 Polymorphisms With Production of IFN-γ and IL-12 in BCG Osteitis Survivors R1.

TLR1 TLR6

6.89e-05592227755461
Pubmed

TLR-dependent control of Francisella tularensis infection and host inflammatory responses.

TLR1 TLR6

6.89e-05592219936231
Pubmed

Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses.

TLR1 TLR6

6.89e-05592215294986
Pubmed

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

TLR1 TLR6

6.89e-05592216880211
Pubmed

Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.

TLR1 TLR6

6.89e-05592223477738
Pubmed

Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk.

TLR1 TLR6

6.89e-05592216537705
Pubmed

A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.

TLR1 TLR6

6.89e-05592219029192
Pubmed

NF-κB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes.

TLR1 TLR6

6.89e-05592224612386
Pubmed

Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.

TLR1 TLR6

6.89e-05592223077245
InteractionPHF21A interactions

RLF PTPN13 ZNF592 DSP NUP43 CRYBG3 ANKHD1 MGA GOLGB1 ZNF687

3.06e-063439010int:PHF21A
Cytoband12p13-p12.2

RAD52 PZP

3.97e-06292212p13-p12.2
Cytoband4p14

TLR1 TLR6 DTHD1

8.45e-05429234p14
CytobandEnsembl 112 genes in cytogenetic band chr4p14

TLR1 TLR6 DTHD1

3.40e-0467923chr4p14
Cytoband5q13

BDP1 POLK

8.94e-04229225q13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

RLF ZNF773 ZNF789 ZNF592 ZNF423 ZBTB43 ZFP14 SALL4 ZNF221 ZNF112 ZNF551

5.25e-05718661128
GeneFamilyCD molecules|Toll like receptors

TLR1 TLR6

5.80e-0410662948
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN13 PTPN22

1.93e-0318662812
GeneFamilyT-boxes

MGA TBX5

1.93e-0318662766
GeneFamilyDNA polymerases

POLL POLK

3.16e-0323662535
GeneFamilyTransient receptor potential cation channels

TRPM1 MCOLN1

4.67e-0328662249
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP6 NBEA

5.00e-0329662396
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLK2 BDP1 SMG1 DTHD1 CBLB UTY GOLGB1

1.90e-07199927f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRMT8 RTL1 CNKSR2 ZNF112 AGBL2 CDCP1

1.83e-061779268abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMG1 DSP SGSM2 SALL4 NBEA GOLGB1

1.96e-061799266e965e424eebef50f0202cff75f458be395cfca1
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 CFAP47 CES4A AGBL2 PZP UBXN10

2.37e-061859265e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CLCA2 DSP DYRK4 KLK3 MUC2

3.03e-06193926402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CLCA2 DSP DYRK4 KLK3 MUC2

3.03e-061939267ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 CFAP161 AGBL2 PZP DTHD1 UBXN10

3.71e-0620092631d75c26055177d656df1fbb10b764cebd61e122
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 CFAP161 AGBL2 PZP DTHD1 UBXN10

3.71e-06200926e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TLR1 SALL4 TRPM1 PZP

7.31e-066092448adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TLR1 SALL4 TRPM1 PZP

7.31e-0660924a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

FCGBP ADAM2 DYRK4 KLK3 MUC2

1.00e-05138925e1e936ff4080bda2810c5fd1154a706359f377a5
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

FCGBP ADAM2 DYRK4 KLK3 MUC2

1.87e-051579255fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CES4A CFAP161 DTHD1 UBXN10 TBX5

1.99e-0515992500a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellBac-SEP-Myeloid-tDC|Bac-SEP / Disease, Lineage and Cell Type

ZNF789 TRIO RHOBTB2 WDR27 CRYBG3

2.37e-051659258728f927502e56f2768b4224e9111939d3d7815a
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 WDR27 CFAP161 DTHD1 UBXN10

2.44e-051669254b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CES4A NBEA AGBL2 PZP DTHD1

2.66e-0516992514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF21B TLR1 GLYCTK PTPN22 HELQ

2.74e-05170925bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B ETAA1 PTPN22 CNKSR2 TBX5

3.06e-051749256987fe7959afce347282f632abc16d800ccab7c4
ToppCellfacs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CLCA2 DSP CDCP1 ITGB4

3.14e-05175925eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|bone_marrow / Manually curated celltypes from each tissue

PTPN22 PZP DTHD1 CBLB UTY

3.89e-0518392537db007cc65005bffc18a5fda7f454a57c9fb0a9
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SMG1 PTPN22 DTHD1 CBLB GOLGB1

3.99e-05184925cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN13 CLCA2 CNKSR2 MEGF10 PRNP

4.31e-051879256f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

CCP110 GKAP1 CFAP161 AGBL2 NPHP4

4.42e-05188925f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 PTPN13 PTPRE SALL4 FAM135B

4.42e-05188925997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

PTPN13 CLCA2 DSP NBEA ITGB4

4.54e-0518992584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 CFAP47 CES4A PZP UBXN10

5.01e-05193925ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 CFAP47 CES4A NBEA DTHD1

5.14e-051949254a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSP CFAP161 CDCP1 ITGB4 UBXN10

5.26e-05195925ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CLCA2 DYRK4 KLK3 MUC2

5.26e-05195925e1fb987f13482d1fce0428413244be3621136424
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP CLCA2 DYRK4 KLK3 MUC2

5.26e-05195925482a2e7db72f0da285bb658943dd668777519734
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA TTC3 MGA UTY GOLGB1

5.26e-051959253e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA TTC3 MGA UTY GOLGB1

5.26e-051959257796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellmLN-T_cell-gd_T|T_cell / Region, Cell class and subclass

KIAA0825 SGSM2 RHOBTB2 PTPN22 CBLB

5.39e-051969258f476408cd5a4ea9d25c763c66565343d7989b38
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 CFAP47 PRMT8 KIAA0825 DTHD1

5.52e-0519792574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellSepsis-Bac-SEP-Myeloid-tDC|Bac-SEP / Disease, condition lineage and cell class

ZNF789 TRIO RHOBTB2 WDR27 CRYBG3

5.79e-05199925a2be40d367338d32348a6906c8475aa3b544a0f7
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF21B PTPN22 PZP DTHD1 CBLB

5.93e-052009257a9c3f51d4a8fda5f1b7e0be6fcf9c1c92fffe99
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPN13 CLCA2 DSP ITGB4 GOLGB1

5.93e-0520092597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 PTPN22 PZP DTHD1 CBLB

5.93e-05200925109f673a4967ffa52270a0b4f818b3461288db44
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN13 CLCA2 DSP ITGB4 GOLGB1

5.93e-05200925ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRMT8 CLCA2 CNKSR2 FAM135B

1.87e-041379244dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRMT8 CLCA2 CNKSR2 FAM135B

1.87e-04137924c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

AKAP6 FCGBP ZNF112 SMURF2

2.09e-041419247671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 PTPN22 UTY GOLGB1

2.44e-0414792494998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CLCA2 DTHD1 FAM135B

2.51e-04148924f58804d24fe524b42b5090c8658050ea4b14793e
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA5B ZNF221 PZP TBX5

2.51e-04148924dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellHippocampus-Macroglia-CSF_related|Hippocampus / BrainAtlas - Mouse McCarroll V32

CFAP161 AGBL2 DTHD1 UBXN10

2.78e-04152924c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFAP47 CFAP161 NPHP4 UBXN10

2.85e-04153924fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFAP47 CFAP161 NPHP4 UBXN10

2.85e-041539242482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RTL1 ZFP14 MUC2 ZMYM6

2.92e-04154924e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 RTL1 DTHD1 HELQ

2.99e-04155924441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN22 CFAP161 DTHD1 CBLB

3.22e-04158924da060f5b61c7088f700d138b02ea596adacf7d60
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CLCA2 ZBTB43 DTHD1

3.29e-04159924c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCellBac-SEP-Lymphocyte-T_NK-dnT|Bac-SEP / Disease, Lineage and Cell Type

RAD52 ZNF773 ETAA1 DTHD1

3.37e-04160924f5ca49801c981b903a85a64b21ece6b59fe91cbc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM1 FAM135B MEGF10 PRNP

3.45e-041619247d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM1 FAM135B MEGF10 PRNP

3.45e-04161924410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM1 FAM135B MEGF10 PRNP

3.45e-0416192471022485da6754a2b57b4c3e758e3de4c95cc292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM1 FAM135B MEGF10 PRNP

3.45e-0416192459ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCellfacs-Skin-nan-24m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CLCA2 EIF3F

3.61e-0467923b89b819b87e327f5f75e76017c3d463007c2baf2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 SALL4 GCKR PZP

3.62e-04163924bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 SALL4 GCKR PZP

3.62e-041639248e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF21B NEIL3 PTPN22 DTHD1

3.70e-04164924649e42d9cfdec2f7771d1e938b516e46e7d07078
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF21B NEIL3 PTPN22 DTHD1

3.70e-04164924ba85f7b21ae34e285d286ada24715885ca6329f7
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tox_(Neuron.Slc17a7.Syt6-Tox)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP161 PZP MUC2

3.77e-0468923b8d472ff47312a8cc8ba60809947c82f4054d8de
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tox_(Neuron.Slc17a7.Syt6-Tox)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP161 PZP MUC2

3.77e-046892394acd088e39a17cd573aa3ad533b6634e3b7018d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP161 PZP MUC2

3.77e-046892389929e9e3a119f6eafef37a401e8fe2bd972452b
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

RLF KIAA0825 ZNF221 AGBL2

3.88e-041669244ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCellfacs-Skin-nan-24m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CLCA2 EIF3F

3.93e-04699230d8d96d01a49cf1bf95b1b324966cbac9b15b4b1
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

CFAP47 PRMT8 CFAP161 UBXN10

3.97e-04167924442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCP110 PTPDC1 ZPBP DYRK4

4.06e-04168924b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellfacs-Trachea-nan-24m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRMT8 CNKSR2 ZNF112 CDCP1

4.06e-041689246c7b490b6c844d0ea4c07edfc24c02284f9533c4
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

PTPN13 ITGB4 FAM135B MEGF10

4.15e-04169924a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 DTHD1 CBLB GOLGB1

4.34e-041719242e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTL1 ZPBP FECH

4.46e-04729235e5eb8c7014396767f3dc7d99cb552edd273bfbd
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTL1 ZPBP FECH

4.46e-047292378e158835ec2a37faadf5acdbb62f266cc184e44
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTL1 ZPBP FECH

4.46e-0472923c4bf1d59845fa54aeb2c8ebeda17bba6641cfb3d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 WDR27 CFAP161 DTHD1

4.53e-04173924a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FCGBP TLR1 ZNF112 TLR6

4.53e-041739241f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 WDR27 CFAP161 DTHD1

4.53e-04173924e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP47 CFAP161 AGBL2 UBXN10

4.63e-04174924f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTL1 ZNF221 NPHP4 TBX5

4.63e-041749247fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RAD52 CLCA2 KIAA0825 ITGB4

4.63e-04174924a0060be3940043015dcc49a5157de5541aed24a1
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

PTPN13 CLCA2 SLC37A2 CRYBG3

4.73e-041759240cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP47 CFAP161 AGBL2 UBXN10

4.73e-04175924c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP TRIO ZPBP ZFP14

4.73e-04175924dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellfacs-Trachea-nan-18m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA2 DSP CDCP1 ITGB4

4.73e-041759243883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Striatum / BrainAtlas - Mouse McCarroll V32

TLR1 TLR6 DYRK4

4.83e-0474923e89506bd854a43b80f839ace36f7a3eaa8437215
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)|Striatum / BrainAtlas - Mouse McCarroll V32

TLR1 TLR6 DYRK4

4.83e-04749230dbce0b36eaf0c7a8b623478c85d1cac82c6693a
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Striatum / BrainAtlas - Mouse McCarroll V32

TLR1 TLR6 DYRK4

4.83e-0474923093575ea862f3724d236817f04d98cc06b8addf0
ToppCellStriatum-Hematopoietic-MICROGLIA|Striatum / BrainAtlas - Mouse McCarroll V32

TLR1 TLR6 DYRK4

4.83e-047492389effada90fbfef1844a905d3f82e9d16666eea5
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Striatum / BrainAtlas - Mouse McCarroll V32

TLR1 TLR6 DYRK4

4.83e-0474923b14a950b90791a4cc5ffd29eb75a524abdd382da
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR27 CFAP161 DTHD1 UBXN10

4.84e-04176924ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CFAP161 DTHD1 UBXN10

4.94e-04177924e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PTPRE SALL4 PZP DTHD1

4.94e-0417792447813ad05527ea583e736b54b7a48f7ad90c3aef
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

KIF21B PTPN22 PZP DTHD1

5.05e-0417892434ec499d03cc198cfefa19a724d4c81974052f65
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CFAP161 DTHD1 UBXN10

5.05e-04178924b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CFAP161 DTHD1 UBXN10

5.05e-04178924579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

FCGBP CLCA2 DSP NBEA

5.15e-041799241fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCP110 CFAP161 DTHD1 UBXN10

5.15e-04179924d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCP110 CFAP161 DTHD1 UBXN10

5.15e-041799248a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellfacs|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA2 DSP CDCP1 ITGB4

5.15e-041799248001db3044e8657980e24422377c4fdb0d7b323e
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BDP1 SMG1 CBLB GOLGB1

1.02e-0449544GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DiseaseIntellectual Disability

AKAP6 TLK2 TRIO RHOBTB2 SDCCAG8 TRIM8 NBEA EIF3F ZMYM6

8.45e-06447899C3714756
DiseaseHolt-Oram syndrome

SALL4 TBX5

9.00e-062892C0265264
DiseaseWildervanck's syndrome

SALL4 TBX5

9.00e-062892C0265239
DiseaseHolt-Oram syndrome (is_implicated_in)

SALL4 TBX5

9.00e-062892DOID:0060468 (is_implicated_in)
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR1 TLR6 MUC2

1.75e-0517893DOID:8677 (biomarker_via_orthology)
DiseaseSenior-Loken syndrome (is_implicated_in)

SDCCAG8 NPHP4

1.87e-047892DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia

SDCCAG8 NPHP4

1.87e-047892cv:C0403553
Diseaseaspergillosis (is_implicated_in)

TLR1 TLR6

2.49e-048892DOID:13564 (is_implicated_in)
Diseasebitter beverage consumption measurement

POR GCKR AGBL2

2.80e-0442893EFO_0010089
Diseasetriacylglycerol 56:6 measurement

FCGBP DSP GCKR

3.00e-0443893EFO_0010433
Diseasenephronophthisis (implicated_via_orthology)

SDCCAG8 NPHP4

3.19e-049892DOID:12712 (implicated_via_orthology)
DiseaseRenal dysplasia and retinal aplasia (disorder)

SDCCAG8 NPHP4

5.82e-0412892C0403553
DiseaseMitral valve prolapse, response to surgery

ZNF592 TBX5

5.82e-0412892EFO_0009951, HP_0001634
Diseaseresponse to antipsychotic drug

LINC02914 NBEA MEGF10

8.02e-0460893GO_0097332
Diseasecoffee consumption, cups of coffee per day measurement

POR GCKR

1.05e-0316892EFO_0004330, EFO_0006782
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TLK2 TRIO

1.19e-0317892DOID:0060307 (is_implicated_in)
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

SEMA5B GCKR POLK

1.20e-0369893EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Diseaselung squamous cell carcinoma (is_implicated_in)

RAD52 PTPN13

2.38e-0324892DOID:3907 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
HIENVHTAQEPSTVC

ZNF280B

361

Q86YH2
VNHKIVHECQELSSP

BDP1

2031

A6H8Y1
DSQHHLSCEPVSQTN

CRYBG3

361

Q68DQ2
HFISKQKSQCLHNQP

ADAM2

361

Q99965
KLQQHTHEKPCNTSF

CDCP1

466

Q9H5V8
IPQKSSHAVCNAQHD

GKAP1

81

Q5VSY0
KPVQCVHHVSTQPSC

PRMT8

41

Q9NR22
VPANAKILINHCHTN

CFAP161

211

Q6P656
CAQPSSQKATNHNLH

POLL

241

Q9UGP5
CVTVFLHHPNNQTLS

NUP43

96

Q8NFH3
VQTVPQTCDGHKAHT

PZP

1351

P20742
TQNRTPHSVCHQKPQ

RAD52

366

P43351
SQAKHCIPEKNHTLQ

PTPN22

306

Q9Y2R2
ETQAHIQECKHPSVF

MCOLN1

276

Q9GZU1
HTLTQCATSPHVNNR

MEGF10

931

Q96KG7
KQQQQTGNHPITVHC

PTPRE

616

P23469
CTSVQKLLNPHQHTD

KIAA0825

706

Q8IV33
SSKVHPNSVHICAVV

POR

461

P16435
PAVKVCQLTDEQIHH

NEIL3

206

Q8TAT5
AAHTQSFKQPSCTHI

MGA

2371

Q8IWI9
PVSLNSQPSHCHNVK

CBLB

716

Q13191
EQTHCIIKRPDNQHV

MUC2

4991

Q02817
KVAHLAGCNHNSTQI

CES4A

266

Q5XG92
HDSPINAICTNAKHI

KIF21B

1586

O75037
NFLHQVCHDQTPTTK

TUBGCP3

491

Q96CW5
VHKDPNPAHQQVSHC

PTPDC1

511

A2A3K4
THVCQLPEDQKGNIH

ITGB4

421

P16144
KNPHNTQHTVTVEID

NPHP4

996

O75161
TNQPCHKTVTDEAQS

ETAA1

796

Q9NY74
PISCHVQVAHEKEQV

GCKR

556

Q14397
LSCQHNPLIINVTHH

PAPPA2

1316

Q9BXP8
HQNCSEQIKPINDTH

SLC37A2

51

Q8TED4
PTKHVQHSGDQQDCL

DYRK4

456

Q9NR20
PTVASSHNVQDCLHI

GLYCTK

256

Q8IVS8
KHSVEVTNCFSVPHN

EIF3F

126

O00303
KHTTCNHVVEQLLPT

FCGBP

231

Q9Y6R7
THHGTCQDVNHNKVI

DSP

641

P15924
SATHQHVRKNNPQCL

AGBL2

41

Q5U5Z8
VCQSSGNHLENKVTH

CCP110

461

O43303
TTACIVLSHQKDNPH

DTHD1

506

Q6ZMT9
CPTVTHSVHSQVLKN

FAM135B

986

Q49AJ0
SSHNTVNEELPHNCI

HELQ

226

Q8TDG4
HSHIQSNELCSKQLT

FECH

386

P22830
HRTNTSIKTQHSCPI

SALL4

616

Q9UJQ4
ICVNSPNTHLLHVIN

CFAP47

761

Q6ZTR5
HITVECQVGNVTQKH

CFAP47

2416

Q6ZTR5
CQVGNVTQKHITLPH

CFAP47

2421

Q6ZTR5
CPSSQHLQSLRHNKQ

LINC02914

41

Q52M58
QSHHEAPKSQEDTIC

PTPN13

1691

Q12923
QICTQHHTEAIGKNN

OSBPL11

151

Q9BXB4
TEPLVCIHQNHQESI

RTL1

476

A6NKG5
TGTCDKVNNIHPAVH

UTY

741

O14607
QHQTSVAHQPVVRQC

TBX5

456

Q99593
EHHTPTILKCSQRVQ

RNF113B

121

Q8IZP6
CAQHEAVLSQTHTNV

SDCCAG8

286

Q86SQ7
ILTEQVCTQVVHKPH

NBEA

816

Q8NFP9
HIDHTQKPSLTQQVS

SMG1

326

Q96Q15
CFSIANPNSLHHVKT

RHOBTB2

106

Q9BYZ6
PFSQVVCIHCHQQKS

SGSM2

321

O43147
AQHGSDQHQVLVCTK

TEN1

46

Q86WV5
SHNKLVKISCHPTVN

TLR1

101

Q15399
TEHSCSSQKQISIQH

TLK2

191

Q86UE8
SSHHDAKNQQPVPCE

AKAP6

351

Q13023
KGQKDTVSLHQQCSH

ANKHD1

861

Q8IWZ3
PHHQLKNTVTVDNTV

CLCA2

506

Q9UQC9
RQSTLPTQKCHLQDH

CNKSR2

806

Q8WXI2
NPTVLCQKLNHGSDH

ZBTB43

126

O43298
HQIDACTNNLPKAHT

SMURF2

701

Q9HAU4
CINQPHLLNQTDKSH

RLF

851

Q13129
FKQPQSHETALHCAV

TNKS

516

O95271
SHIPQHQVDSSTAQC

ZNF592

1141

Q92610
LPSKSFNIEHCHQNS

POLK

731

Q9UBT6
TCKNTLVQHQQIHTG

ZNF551

261

Q7Z340
QHQNSSVISRLHPCV

TTC3

96

P53804
VHDCVNITIKQHTVT

PRNP

176

P04156
HCQRQSQESTLVHPA

SEMA5B

1061

Q9P283
DLSHNQLQKISCHPI

TLR6

106

Q9Y2C9
LHQKSPHVLCVTQQL

ZPBP

76

Q9BS86
DVKTHLVPECQNSLH

TRPM1

1311

Q7Z4N2
EVPSSNVQQHQKQHC

ZNF773

106

Q6PK81
CRQVDVPKHQTNQTH

TOPAZ1

526

Q8N9V7
FNQSSCLQVHQKIHT

ZNF112

396

Q9UJU3
VTQTKATSCKPHTQH

ZMYM6

696

O95789
ATSCKPHTQHKECQT

ZMYM6

701

O95789
SSCLLNHQQVHSGQK

ZNF221

406

Q9UK13
VNSIKSHIQTSHCEV

ZNF687

776

Q8N1G0
QKSQGVEVCAHHIPS

UBXN10

51

Q96LJ8
ICQQLTVHQSIHTGE

ZFP14

351

Q9HCL3
TIHADKPQQSHTCQI

ZNF423

431

Q2M1K9
IAEAHSRPVHQICQN

WDR27

696

A2RRH5
EAPCCQSHVQTHLQQ

TRIM8

111

Q9BZR9
NKTPHNSSINHIETV

TRIO

746

O75962
STLLCHQQIHSKPNT

ZNF789

326

Q5FWF6
HQQIHSKPNTHKCSE

ZNF789

331

Q5FWF6
TEQHHTQPVLESNLC

GOLGB1

1271

Q14789
LHVISNDVCAQVHPQ

KLK3

176

P07288