Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhormone binding

RXFP1 MTNR1A

5.44e-0410372GO:0042562
GeneOntologyMolecularFunctionG protein-coupled receptor activity

RXFP1 RHO MTNR1A

2.65e-0388473GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

RXFP1 RHO MTNR1A

8.83e-03135373GO:0004888
GeneOntologyBiologicalProcessphosphatidylinositol phosphate biosynthetic process

TTC7A INPP4A

2.10e-046672GO:0046854
GeneOntologyBiologicalProcessregulation of lymphocyte migration

SLC8B1 DOCK8

2.85e-047772GO:2000401
GeneOntologyBiologicalProcesslymphocyte migration

SLC8B1 DOCK8

6.46e-0411672GO:0072676
GeneOntologyBiologicalProcessphosphatidylinositol biosynthetic process

TTC7A INPP4A

8.36e-0413272GO:0006661
GeneOntologyBiologicalProcessregulation of mononuclear cell migration

SLC8B1 DOCK8

1.22e-0316072GO:0071675
GeneOntologyBiologicalProcessphosphatidylinositol metabolic process

TTC7A INPP4A

1.38e-0317072GO:0046488
GeneOntologyBiologicalProcessglycerophospholipid biosynthetic process

TTC7A INPP4A

2.23e-0321772GO:0046474
GeneOntologyBiologicalProcessregulation of insulin secretion

SLC8B1 MTNR1A

2.53e-0323172GO:0050796
GeneOntologyBiologicalProcessmononuclear cell migration

SLC8B1 DOCK8

3.14e-0325872GO:0071674
GeneOntologyBiologicalProcessregulation of leukocyte migration

SLC8B1 DOCK8

3.36e-0326772GO:0002685
GeneOntologyBiologicalProcessglycerolipid biosynthetic process

TTC7A INPP4A

3.38e-0326872GO:0045017
GeneOntologyBiologicalProcessphospholipid biosynthetic process

TTC7A INPP4A

3.38e-0326872GO:0008654
GeneOntologyBiologicalProcessinsulin secretion

SLC8B1 MTNR1A

3.53e-0327472GO:0030073
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

SLC8B1 MTNR1A

3.61e-0327772GO:0090276
GeneOntologyBiologicalProcessregulation of peptide transport

SLC8B1 MTNR1A

3.74e-0328272GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

SLC8B1 MTNR1A

3.74e-0328272GO:0002791
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

RXFP1 MTNR1A

3.84e-0328672GO:0007188
GeneOntologyBiologicalProcessglycerophospholipid metabolic process

TTC7A INPP4A

4.79e-0332072GO:0006650
GeneOntologyBiologicalProcesspeptide hormone secretion

SLC8B1 MTNR1A

5.20e-0333472GO:0030072
GeneOntologyBiologicalProcesspeptide secretion

SLC8B1 MTNR1A

5.48e-0334372GO:0002790
GeneOntologyBiologicalProcessregulation of protein secretion

SLC8B1 MTNR1A

5.70e-0335072GO:0050708
GeneOntologyBiologicalProcessregulation of hormone secretion

SLC8B1 MTNR1A

5.86e-0335572GO:0046883
GeneOntologyBiologicalProcesspeptide transport

SLC8B1 MTNR1A

5.86e-0335572GO:0015833
GeneOntologyBiologicalProcessphospholipid metabolic process

TTC7A INPP4A

7.75e-0341072GO:0006644
GeneOntologyBiologicalProcesshormone secretion

SLC8B1 MTNR1A

8.12e-0342072GO:0046879
GeneOntologyBiologicalProcessamide transport

SLC8B1 MTNR1A

8.12e-0342072GO:0042886
GeneOntologyBiologicalProcessglycerolipid metabolic process

TTC7A INPP4A

8.46e-0342972GO:0046486
GeneOntologyBiologicalProcesshormone transport

SLC8B1 MTNR1A

8.57e-0343272GO:0009914
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

RXFP1 RHO MTNR1A

8.79e-03139573GO:0007186
GeneOntologyBiologicalProcessleukocyte migration

SLC8B1 DOCK8

9.24e-0344972GO:0050900
GeneOntologyBiologicalProcessprotein secretion

SLC8B1 MTNR1A

1.05e-0248072GO:0009306
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

SLC8B1 MTNR1A

1.06e-0248372GO:0035592
GeneOntologyBiologicalProcessprotein localization to extracellular region

SLC8B1 MTNR1A

1.09e-0249072GO:0071692
GeneOntologyBiologicalProcesstaxis

SLC8B1 RHO

1.22e-0251972GO:0042330
MousePhenodecreased a-wave amplitude

RHO MTNR1A

4.68e-046772MP:0012143
MousePhenoabnormal photoreceptor inner segment morphology

RHO MTNR1A

4.82e-046872MP:0003730
MousePhenoabnormal a-wave amplitude

RHO MTNR1A

4.96e-046972MP:0012030
MousePhenoabnormal a-wave shape

RHO MTNR1A

5.11e-047072MP:0012034
MousePhenoshort photoreceptor outer segment

RHO MTNR1A

5.86e-047572MP:0008587
MousePhenoabnormal photoreceptor outer segment size

RHO MTNR1A

6.34e-047872MP:0020811
MousePhenoneuron degeneration

RHO MTNR1A INPP4A

6.99e-0439173MP:0003224
MousePhenodecreased b-wave amplitude

RHO MTNR1A

7.00e-048272MP:0012144
MousePhenoabnormal b-wave shape

RHO MTNR1A

7.52e-048572MP:0012035
MousePhenoabnormal b-wave amplitude

RHO MTNR1A

7.52e-048572MP:0012031
MousePhenoabnormal electroretinogram waveform feature

RHO MTNR1A

1.17e-0310672MP:0012029
MousePhenoneurodegeneration

RHO MTNR1A INPP4A

1.18e-0346873MP:0002229
MousePhenoretina photoreceptor degeneration

RHO MTNR1A

1.28e-0311172MP:0008450
MousePhenoabnormal photoreceptor outer segment morphology

RHO MTNR1A

2.05e-0314172MP:0003729
Domain7TM_GPCR_Srsx

RHO MTNR1A

7.34e-0411272SM01381
DomainGPCR_Rhodpsn_7TM

RXFP1 RHO MTNR1A

1.44e-0367073IPR017452
Domain7tm_1

RXFP1 RHO MTNR1A

1.49e-0367773PF00001
DomainG_PROTEIN_RECEP_F1_1

RXFP1 RHO MTNR1A

1.54e-0368573PS00237
DomainG_PROTEIN_RECEP_F1_2

RXFP1 RHO MTNR1A

1.58e-0369173PS50262
DomainGPCR_Rhodpsn

RXFP1 RHO MTNR1A

1.59e-0369273IPR000276
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

RXFP1 RHO MTNR1A

2.41e-0433063M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

RXFP1 RHO MTNR1A

2.48e-0433363MM14963
PathwayREACTOME_GPCR_LIGAND_BINDING

RXFP1 RHO MTNR1A

5.26e-0443063MM15160
PathwayREACTOME_GPCR_LIGAND_BINDING

RXFP1 RHO MTNR1A

6.54e-0446363M507
PathwayREACTOME_SIGNALING_BY_GPCR

RXFP1 RHO MTNR1A

1.73e-0364663MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

RXFP1 RHO MTNR1A

2.20e-0370263M746
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

RHO MTNR1A

2.51e-0318662MM15994
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

RHO MTNR1A

4.84e-0326062M39397
PathwayWP_GPCRS_NONODORANT

RXFP1 MTNR1A

5.06e-0326662MM15843
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

RXFP1 MTNR1A

5.29e-0327262M13380
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

RHO MTNR1A

5.95e-0328962MM15057
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

RHO MTNR1A

6.99e-0331462M600
CoexpressionGSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_DN

TTC7A INPP4A

6.53e-0414872M9427
CoexpressionGSE25677_MPL_VS_R848_STIM_BCELL_UP

RXFP1 MTNR1A

9.00e-0417472M8186
CoexpressionIL21_UP.V1_DN

SLC8B1 MTNR1A

1.03e-0318672M2824
CoexpressionGSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN

DOCK8 INPP4A

1.11e-0319372M3149
CoexpressionGSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP

SLC8B1 INPP4A

1.14e-0319672M5349
CoexpressionGSE15659_NAIVE_CD4_TCELL_VS_RESTING_TREG_DN

TTC7A SLC8B1

1.16e-0319872M3542
CoexpressionGSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_DN

TTC7A SLC8B1

1.17e-0319972M3554
CoexpressionGSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP

SLC8B1 INPP4A

1.19e-0320072M9000
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP

TTC7A DOCK8

1.19e-0320072M10032
CoexpressionGSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP

TTC7A SLC8B1

1.19e-0320072M8468
CoexpressionGSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP

DOCK8 INPP4A

1.19e-0320072M4103
CoexpressionGSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP

DOCK8 INPP4A

1.19e-0320072M7515
CoexpressionGSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_DN

DOCK8 INPP4A

1.19e-0320072M7757
CoexpressionGSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN

SLC8B1 DOCK8

1.19e-0320072M7992
CoexpressionGSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_UP

RHO INPP4A

1.19e-0320072M9076
CoexpressionGSE7509_DC_VS_MONOCYTE_DN

RHO INPP4A

1.19e-0320072M6829
CoexpressionGSE27786_LIN_NEG_VS_MONO_MAC_DN

SLC8B1 RHO

1.19e-0320072M4798
CoexpressionLEE_DIFFERENTIATING_T_LYMPHOCYTE

DOCK8 INPP4A

1.20e-0320172M2200
CoexpressionDESCARTES_MAIN_FETAL_PAEP_MECOM_POSITIVE_CELLS

RXFP1 MTNR1A

1.33e-0321272M40131
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

RHO MTNR1A

1.67e-0323872M2020
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

DOCK8 RHO

1.77e-0324572M18095
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

RHO MTNR1A

2.01e-0326172MM1277
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

DOCK8 RHO

2.10e-0326772MM984
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A DOCK8 INPP4A

2.04e-0617673238244294d08975df6bfa26b2b437db3654408ae
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RXFP1 MTNR1A

6.85e-0582721ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RXFP1 MTNR1A

6.85e-058272a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RXFP1 MTNR1A

6.85e-058272cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Hippocampus / BrainAtlas - Mouse McCarroll V32

TTC7A RXFP1

1.30e-04113726f270b7e59c18243e876311df721e948ce21e850
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RXFP1 MTNR1A

2.14e-041457278f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

2.61e-04160721e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC7A DOCK8

2.61e-0416072bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC7A DOCK8

2.61e-0416072af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC7A DOCK8

2.61e-04160722020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TTC7A RXFP1

2.64e-041617266554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

2.91e-04169722a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A DOCK8

2.94e-0417072e319ab46842d028898c09d6d8f056f896edb1558
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 SLC8B1

2.98e-0417172f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 SLC8B1

2.98e-04171726a489a75eeab2a2d48d604682e93599c20a945fe
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

2.98e-04171729e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC7A DOCK8

2.98e-04171724ad28ecfde3d529a09b80be908c446bd5274518e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 SLC8B1

3.01e-041727292e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.05e-04173725aa4d45a01d2d09eff8b4deb32bd91ab2471210a
ToppCellfacs-Lung-EPCAM-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC7A DOCK8

3.05e-041737250b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.05e-04173720bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 SLC8B1

3.08e-04174722947e5906b172d149412fa4e77476fce4ea695d2
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 INPP4A

3.08e-0417472ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CD24|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 SLC8B1

3.08e-04174723e29d620b7b4ab1915ddac70ee5a50d09072292b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.08e-04174725f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.12e-041757206af6629766e2054e6995e8cdb3907658fec49d3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.12e-04175721d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.12e-041757277c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.15e-0417672c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RXFP1 DOCK8

3.19e-0417772a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8B1 DOCK8

3.19e-04177723cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RXFP1 DOCK8

3.19e-04177723645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.23e-0417872a48739a588f361b4bc69405d7e256c11f61cf43c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.26e-0417972e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A DOCK8

3.26e-0417972223f0895da89c7606f637aef113912dd06f39c5a
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC8B1 DOCK8

3.26e-0417972b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.30e-0418072cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.30e-0418072b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A DOCK8

3.30e-0418072cb6b11883f42c8beff07f899036c803d786ac6a3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.30e-0418072f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.34e-041817230729f0364f719c044712a51453e22dc2c1a232b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 INPP4A

3.34e-04181725a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.41e-04183723ebe334ad570e3525341badb558f369c61daf3d3
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.45e-04184729cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 RHO

3.48e-0418572a1b2525da018abe458908cab7268bd403ee98d92
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A INPP4A

3.56e-041877242b20d7f0a4f9195b3d71dc0e089b5e0914ebcbb
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 INPP4A

3.56e-04187726bdc55213e41346c5914a290b16172cd412ac71d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RXFP1 DOCK8

3.67e-04190725681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellwk_20-22-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TTC7A SLC8B1

3.67e-0419072f49ceda3622cf079cffde9c9a9e3d0380c571d39
ToppCellwk_15-18-Hematologic_Lymphocytic-B-pre-B-I_cell|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TTC7A SLC8B1

3.71e-0419172146edd214aac49f9b910bb982e3d77a052c8b316
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC8B1 DOCK8

3.83e-04194723043f6230fa723037c8cf7123f611ae847b39fd4
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC7A INPP4A

3.87e-041957269201b1172bcf0999c726516e4d30863afceab0b
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK8 INPP4A

4.03e-0419972eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK8 INPP4A

4.03e-04199721bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

SLC8B1 DOCK8

4.07e-0420072e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellNeuronal-Excitatory-eB(RORB)-FOLH1B--|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 SLC8B1

4.07e-0420072bdda59ffa0496256dd7a5937e88baac5c2a656c3
ToppCellNeuronal-Excitatory-eB(RORB)-FOLH1B|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 SLC8B1

4.07e-0420072dff0be30309b6f5f8757b0378ef05ce97f75dbe8
ToppCellNeuronal-Excitatory-eB(RORB)-FOLH1B-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 SLC8B1

4.07e-04200725c0c09e7b84fed053b299848bdff63ab842a445c
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-COL22A1--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 MTNR1A

4.07e-042007242aa70483ea8ca7b7b80831356c9ded82841b941
ToppCellNeuronal-Excitatory-eB(RORB)-FOLH1B---L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 SLC8B1

4.07e-0420072c3474e8a03ec4869fd3636a5559d36dd9c5fd414
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-COL22A1|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 MTNR1A

4.07e-0420072ac1ce87f8a79926029e77d3912cd5edfb7aa8202
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-COL22A1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RXFP1 MTNR1A

4.07e-0420072e87c02fbb0d85de7e63c98b7fc2aca424feeeedc
Drugretinoic acid; Up 200; 1uM; MCF7; HG-U133A

SLC8B1 RHO INPP4A

1.98e-0519173224_UP
Drugindomethacin, USP; Down 200; 20uM; MCF7; HG-U133A

SLC8B1 RHO INPP4A

2.14e-0519673262_DN
DrugMK-886; Down 200; 1uM; MCF7; HG-U133A

SLC8B1 MTNR1A INPP4A

2.24e-0519973264_DN
DrugTryptamine

RHO MTNR1A

3.13e-048972CID000001150
DrugPhenoxybenzamine hydrochloride [63-92-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

RHO MTNR1A

1.19e-03174725613_UP
Drugtrichostatin A; Up 200; 0.1uM; MCF7; HG-U133A

SLC8B1 INPP4A

1.36e-0318672332_UP
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.40e-03189721700_UP
DrugNaringenine [480-41-1]; Up 200; 14.6uM; HL60; HT_HG-U133A

SLC8B1 INPP4A

1.42e-03190721342_UP
Drug(+,-)-Synephrine [94-07-5]; Up 200; 24uM; HL60; HT_HG-U133A

SLC8B1 INPP4A

1.42e-03190726156_UP
DrugPipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.44e-03192723460_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.44e-03192723612_DN
DrugPrazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; HL60; HT_HG-U133A

SLC8B1 INPP4A

1.46e-03193723098_DN
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; PC3; HT_HG-U133A

RHO MTNR1A

1.47e-03194724224_UP
Drugsemustine; Up 200; 100uM; MCF7; HT_HG-U133A

RHO INPP4A

1.47e-03194727487_UP
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; PC3; HT_HG-U133A

RHO INPP4A

1.47e-03194726738_UP
DrugCarbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.47e-03194725342_UP
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.47e-03194727000_UP
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.47e-03194725531_UP
DrugAndrosterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.47e-03194722650_DN
DrugRolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.49e-03195725330_UP
DrugCarbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A

SLC8B1 INPP4A

1.49e-03195725399_DN
DiseaseCombined immunodeficiency

TTC7A DOCK8

2.82e-054162C0494261
DiseaseProfound Mental Retardation

DOCK8 INPP4A

3.26e-0413962C0020796
DiseaseMental deficiency

DOCK8 INPP4A

3.26e-0413962C0917816
DiseaseMental Retardation, Psychosocial

DOCK8 INPP4A

3.26e-0413962C0025363
Diseasehip circumference

TTC7A DOCK8

1.90e-0333862EFO_0005093
DiseaseIntellectual Disability

DOCK8 INPP4A

3.30e-0344762C3714756

Protein segments in the cluster

PeptideGeneStartEntry
WSLVVLAIERYVVVC

RHO

126

P08100
CWESLRRQIVTQYQT

INPP4A

286

Q96PE3
CVQTYIREWLIVNRK

DOCK8

121

Q8NF50
VVTVILCTWIYQRQR

SLC8B1

241

Q6J4K2
IIQRVFVWVVSAVTC

RXFP1

406

Q9HBX9
VTCRQVLRLWQTLYS

TTC7A

621

Q9ULT0
CYLRIWILVLQVRQR

MTNR1A

206

P48039