Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	1.24e-04	3	129	2	GO:0018858
GeneOntologyMolecularFunction	acyltransferase activity	CUL2 RAD18 TRIM2 MOGAT1 GLYATL2 HUWE1 MDM2 KAT2B ZNF451 RNFT1 UBR3 TAF10 TRIM36 ACSM2A ACSM2B	1.46e-04	775	129	15	GO:0016746
GeneOntologyMolecularFunction	Y-form DNA binding	RAD18 MEN1	2.46e-04	4	129	2	GO:0000403
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	2.46e-04	4	129	2	GO:0102391
GeneOntologyBiologicalProcess	negative regulation of cell cycle process	CCP110 RB1 WEE1 APC MDM2 NSUN2 MEN1 TAOK2 SLFN12L KAT2B TAOK3 ETAA1 DNA2	4.55e-07	362	129	13	GO:0010948
GeneOntologyBiologicalProcess	cell cycle process	CUL2 CCP110 MYH9 RAD18 IQGAP2 RB1 WEE1 APC SYCP3 TEX15 PSTPIP1 MDM2 NSUN2 PRPF40A MEN1 TAOK2 SLFN12L KAT2B TAOK3 MKI67 ETAA1 SHOC1 TAF10 TRIM36 DNA2 ANAPC7	8.02e-07	1441	129	26	GO:0022402
GeneOntologyBiologicalProcess	negative regulation of cell cycle	CCP110 BRINP3 RB1 WEE1 APC MDM2 NSUN2 MEN1 TAOK2 SLFN12L KAT2B TAOK3 ETAA1 DNA2	1.29e-06	464	129	14	GO:0045786
GeneOntologyBiologicalProcess	negative regulation of cell cycle phase transition	RB1 WEE1 APC MDM2 NSUN2 MEN1 TAOK2 SLFN12L TAOK3 ETAA1 DNA2	4.21e-06	311	129	11	GO:1901988
GeneOntologyBiologicalProcess	mitotic cell cycle	CUL2 BRINP3 IQGAP2 RB1 WEE1 APC SYCP3 MDM2 MEN1 TAOK2 SLFN12L KAT2B TAOK3 MKI67 ETAA1 TAF10 TRIM36 DNA2 ANAPC7	1.78e-05	1014	129	19	GO:0000278
GeneOntologyBiologicalProcess	regulation of cell cycle process	CCP110 RAD18 RB1 WEE1 APC MDM2 NSUN2 PRPF40A MEN1 TAOK2 SLFN12L KAT2B TAOK3 MKI67 ETAA1 DNA2 ANAPC7	2.10e-05	845	129	17	GO:0010564
GeneOntologyBiologicalProcess	mitotic cell cycle process	CUL2 IQGAP2 RB1 WEE1 APC MDM2 MEN1 TAOK2 SLFN12L KAT2B TAOK3 MKI67 ETAA1 TAF10 TRIM36 DNA2 ANAPC7	2.41e-05	854	129	17	GO:1903047
GeneOntologyBiologicalProcess	cell cycle phase transition	CUL2 RB1 WEE1 APC MDM2 NSUN2 MEN1 TAOK2 SLFN12L TAOK3 ETAA1 TAF10 DNA2 ANAPC7	3.90e-05	627	129	14	GO:0044770
GeneOntologyBiologicalProcess	negative regulation of cell cycle G1/S phase transition	RB1 WEE1 APC MDM2 MEN1 SLFN12L	6.37e-05	109	129	6	GO:1902807
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	LIMA1 MYH9 IQGAP2 APC TOGARAM1 NEB DNAI3 ARPC2 TAOK2 KAT2B AKAP13 PRKD1 TRIM36	7.06e-05	579	129	13	GO:0051493
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle	BRINP3 RB1 WEE1 APC MDM2 TAOK2 SLFN12L TAOK3 ETAA1	7.20e-05	282	129	9	GO:0045930
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle phase transition	RB1 WEE1 APC MDM2 TAOK2 SLFN12L TAOK3 ETAA1	7.21e-05	219	129	8	GO:1901991
GeneOntologyBiologicalProcess	mitotic cell cycle phase transition	CUL2 RB1 WEE1 APC MDM2 MEN1 TAOK2 SLFN12L TAOK3 ETAA1 TAF10 ANAPC7	8.58e-05	509	129	12	GO:0044772
GeneOntologyBiologicalProcess	regulation of organelle organization	CCP110 LIMA1 MYH9 IQGAP2 RB1 APC TOGARAM1 HUWE1 NEB DNAI3 ARPC2 NOD2 TAOK2 SNX30 KAT2B MKI67 AKAP13 PRKD1 TRIM36 TASOR ANAPC7	8.71e-05	1342	129	21	GO:0033043
GeneOntologyBiologicalProcess	regulation of cell cycle phase transition	RB1 WEE1 APC MDM2 NSUN2 MEN1 TAOK2 SLFN12L TAOK3 ETAA1 DNA2 ANAPC7	9.76e-05	516	129	12	GO:1901987
GeneOntologyBiologicalProcess	cell division	CCP110 MYH9 IQGAP2 RB1 WEE1 APC SYCP3 PSTPIP1 NSUN2 PRPF40A MEN1 KAT2B TRIM36 ANAPC7	1.20e-04	697	129	14	GO:0051301
GeneOntologyBiologicalProcess	regulation of mitotic cell cycle phase transition	RB1 WEE1 APC MDM2 MEN1 TAOK2 SLFN12L TAOK3 ETAA1 ANAPC7	2.22e-04	402	129	10	GO:1901990
GeneOntologyBiologicalProcess	tRNA stabilization	NSUN2 SLFN12L	2.31e-04	4	129	2	GO:0036416
GeneOntologyBiologicalProcess	negative regulation of tRNA metabolic process	NSUN2 SLFN12L	2.31e-04	4	129	2	GO:1903327
GeneOntologyBiologicalProcess	negative regulation of tRNA catabolic process	NSUN2 SLFN12L	2.31e-04	4	129	2	GO:1902371
GeneOntologyBiologicalProcess	striated muscle cell development	KRT8 NEB AKAP13 PRKD1 DMD	2.41e-04	89	129	5	GO:0055002
GeneOntologyBiologicalProcess	regulation of chromosome segregation	RAD18 RB1 APC KAT2B MKI67 ANAPC7	2.42e-04	139	129	6	GO:0051983
GeneOntologyBiologicalProcess	regulation of cell cycle	CCP110 BRINP3 RAD18 RB1 WEE1 APC MDM2 NSUN2 PRPF40A MEN1 TAOK2 SLFN12L KAT2B TAOK3 MKI67 ETAA1 TRIM36 DNA2 ANAPC7	3.01e-04	1256	129	19	GO:0051726
GeneOntologyBiologicalProcess	cytokinesis	CCP110 MYH9 IQGAP2 APC PSTPIP1 PRPF40A TRIM36	3.02e-04	204	129	7	GO:0000910
GeneOntologyBiologicalProcess	G1/S transition of mitotic cell cycle	CUL2 RB1 WEE1 APC MDM2 MEN1 SLFN12L TAF10	3.10e-04	271	129	8	GO:0000082
GeneOntologyBiologicalProcess	response to ether	MDM2 ITGAM ARPC2	3.37e-04	22	129	3	GO:0045472
GeneOntologyBiologicalProcess	regulation of mitotic cell cycle	BRINP3 RB1 WEE1 APC MDM2 MEN1 TAOK2 SLFN12L TAOK3 MKI67 ETAA1 ANAPC7	3.56e-04	594	129	12	GO:0007346
GeneOntologyBiologicalProcess	negative regulation of G1/S transition of mitotic cell cycle	RB1 WEE1 APC MDM2 SLFN12L	3.78e-04	98	129	5	GO:2000134
GeneOntologyBiologicalProcess	regulation of tRNA stability	NSUN2 SLFN12L	3.83e-04	5	129	2	GO:0036415
GeneOntologyBiologicalProcess	regulation of tRNA catabolic process	NSUN2 SLFN12L	3.83e-04	5	129	2	GO:1902370
GeneOntologyBiologicalProcess	regulation of actin filament-based process	LIMA1 MYH9 IQGAP2 NEB DNAI3 ARPC2 TAOK2 CTNNA3 AKAP13 PRKD1	4.37e-04	438	129	10	GO:0032970
GeneOntologyBiologicalProcess	cell cycle checkpoint signaling	APC MDM2 NSUN2 TAOK2 TAOK3 ETAA1 DNA2	4.37e-04	217	129	7	GO:0000075
GeneOntologyBiologicalProcess	sarcomere organization	KRT8 NEB AKAP13 PRKD1	5.09e-04	59	129	4	GO:0045214
GeneOntologyBiologicalProcess	positive regulation of stress-activated protein kinase signaling cascade	NOD2 TAOK2 TAOK3	5.59e-04	26	129	3	GO:0070304
GeneOntologyBiologicalProcess	positive regulation of stress-activated MAPK cascade	NOD2 TAOK2 TAOK3	5.59e-04	26	129	3	GO:0032874
GeneOntologyBiologicalProcess	regulation of tRNA metabolic process	NSUN2 SLFN12L	5.73e-04	6	129	2	GO:1903326
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.22e-06	4	127	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.22e-06	4	127	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	1.22e-06	4	127	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	1.22e-06	4	127	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	1.22e-06	4	127	3	IPR015753
Domain	WW_DOMAIN_1	IQGAP2 PRPF40A PLEKHA5 DMD	3.98e-04	51	127	4	PS01159
Domain	WW_DOMAIN_2	IQGAP2 PRPF40A PLEKHA5 DMD	3.98e-04	51	127	4	PS50020
Domain	WW_dom	IQGAP2 PRPF40A PLEKHA5 DMD	4.29e-04	52	127	4	IPR001202
Pathway	REACTOME_ASPIRIN_ADME	UGT3A1 GLYATL2 ABCC2 ACSM2A ACSM2B	1.10e-05	44	95	5	M45014
Pathway	REACTOME_AMINO_ACID_CONJUGATION	GLYATL2 ACSM2A ACSM2B	2.42e-05	9	95	3	M26968
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	2.13e-07	4	132	3	22419166
Pubmed	Acetylation regulates the differentiation-specific functions of the retinoblastoma protein.	RB1 MDM2 KAT2B	5.31e-07	5	132	3	15044952
Pubmed	Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.	RB1 MDM2 MKI67	1.06e-06	6	132	3	25263199
Pubmed	Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis.	SYCP3 MKI67 PLEKHA5	1.85e-06	7	132	3	19838304
Pubmed	A human MAP kinase interactome.	KRT8 MYH9 HIVEP2 APC NEB NUP54 ZNF451 DIAPH2 PLEKHA5 AKAP13 DMD	2.69e-06	486	132	11	20936779
Pubmed	Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility.	SYCP3 MDM2 PLEKHA5	6.29e-06	10	132	3	26470726
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	6.29e-06	10	132	3	23064749
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	FLT1 RAD18 RB1 APC MDM2 MEN1 NOD2 CD48 ABCC2	8.37e-06	351	132	9	20453000
Pubmed	Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.	RB1 MEN1	1.43e-05	2	132	2	17173065
Pubmed	Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.	HIVEP2 HIVEP3	1.43e-05	2	132	2	20404140
Pubmed	Developmental expression of canalicular transporter genes in human liver.	SLC10A1 ABCC2	1.43e-05	2	132	2	15922475
Pubmed	Interaction between the retinoblastoma protein and the oncoprotein MDM2.	RB1 MDM2	1.43e-05	2	132	2	7791904
Pubmed	Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis.	APC MKI67	1.43e-05	2	132	2	33658388
Pubmed	PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.	KRT8 MYH9	1.43e-05	2	132	2	26126491
Pubmed	Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression.	SEMA3F SEMA3C	1.43e-05	2	132	2	27558236
Pubmed	Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.	APC MDM2	1.43e-05	2	132	2	27617574
Pubmed	Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy.	AKAP13 PRKD1	1.43e-05	2	132	2	26192751
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	1.43e-05	2	132	2	29948332
Pubmed	Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.	RB1 MEN1	1.43e-05	2	132	2	17893233
Pubmed	Regional localization of the human c-ros-1 on 6q22 and flt on 13q12.	FLT1 ROS1	1.43e-05	2	132	2	3115921
Pubmed	MDM2 regulates RB levels during genotoxic stress.	RB1 MDM2	1.43e-05	2	132	2	33185004
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	1.43e-05	2	132	2	19634011
Pubmed	Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor.	CUL2 RB1	1.43e-05	2	132	2	17609271
Pubmed	MDM2 and Ki-67 predict for distant metastasis and mortality in men treated with radiotherapy and androgen deprivation for prostate cancer: RTOG 92-02.	MDM2 MKI67	1.43e-05	2	132	2	19470936
Pubmed	Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.	RB1 APC	1.43e-05	2	132	2	16585182
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	1.43e-05	2	132	2	16521160
Pubmed	5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.	RB1 MDM2	1.43e-05	2	132	2	21990374
Pubmed	Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.	RB1 MEN1	1.43e-05	2	132	2	25537453
Pubmed	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.	HIVEP2 HIVEP3	1.43e-05	2	132	2	2247438
Pubmed	Identification and cloning of the cDNA of a Rb-associated protein RAP140a.	RB1 TASOR	1.43e-05	2	132	2	18726359
Pubmed	Lack of glutamate transporter EAAC1 in the epididymis of infertile c-ros receptor tyrosine-kinase deficient mice.	SLC1A1 ROS1	1.43e-05	2	132	2	12399522
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CCP110 RAD18 RB1 WEE1 APC MCCC1 HUWE1 MDM2 ALKBH5 ARFGEF3 ZNF451	1.61e-05	588	132	11	38580884
Pubmed	An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy.	LHCGR MKI67 PLEKHA5	1.89e-05	14	132	3	32011766
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	LIMA1 MYH9 NAP1L4 HLX MCCC1 NSUN2 MKI67 DMD	1.94e-05	298	132	8	30737378
Pubmed	Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System.	SEMA3F RB1 MKI67	2.35e-05	15	132	3	27667971
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	CCP110 KRT8 MYH9 RAD18 APC HUWE1 RFC1 MKI67 PLEKHA5 AKAP13	2.37e-05	503	132	10	16964243
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	WEE1 NSD2 HUWE1 MDM2 MEN1 MKI67	3.15e-05	157	132	6	30686591
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CUL2 CCP110 LETMD1 MYH9 NSD2 NUP54 INTS2 VPS35L PLEKHA5 DNA2 ATP2B1 MTCH1	3.22e-05	754	132	12	33060197
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	CCP110 LIMA1 TEX15 RFC1 NEB PRPF40A DMD	3.30e-05	234	132	7	36243803
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT8 LIMA1 MYH9 IQGAP2 NSD2 KRBA2 NEB NUP54 MEN1 ARPC2 BPTF GUCY1A2 DMD ABCC2 TASOR ATP2B1 ANAPC7	3.42e-05	1442	132	17	35575683
Pubmed	The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation.	SYCP3 NSUN2 MKI67	3.50e-05	17	132	3	23401851
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	SEMA3F SEMA3C PLXNC1	3.50e-05	17	132	3	17626059
Pubmed	Hemidesmosome integrity protects the colon against colitis and colorectal cancer.	KRT8 ITGAM MKI67	4.18e-05	18	132	3	27371534
Pubmed	Retinoblastoma protein represses E2F3 to maintain Sertoli cell quiescence in mouse testis.	RB1 PLEKHA5	4.28e-05	3	132	2	31308245
Pubmed	Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.	RB1 MDM2	4.28e-05	3	132	2	9003773
Pubmed	Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors.	WEE1 MDM2	4.28e-05	3	132	2	26431163
Pubmed	Three-dimensional mapping reveals heterochronic development of the neuromuscular system in postnatal mouse skeletal muscles.	MKI67 DMD	4.28e-05	3	132	2	36347940
Pubmed	Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF in esophageal squamous cell carcinoma.	NSUN2 BPTF	4.28e-05	3	132	2	29763634
Pubmed	Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-γ-stimulated antitumor immunity.	NSD2 APC	4.28e-05	3	132	2	35230972
Pubmed	Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells.	RB1 PLEKHA5	4.28e-05	3	132	2	24901045
Pubmed	Expression of the proliferating cell nuclear antigen and protein products of tumour suppressor genes in the human foetal testis.	RB1 APC	4.28e-05	3	132	2	14871261
Pubmed	TAO kinases mediate activation of p38 in response to DNA damage.	TAOK2 TAOK3	4.28e-05	3	132	2	17396146
Pubmed	MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation.	MDM2 KAT2B	4.28e-05	3	132	2	12068014
Pubmed	Whole-exome sequencing in osteosarcoma reveals important heterogeneity of genetic alterations.	RB1 MDM2	4.28e-05	3	132	2	26787232
Pubmed	Nutlin-3 affects expression and function of retinoblastoma protein: role of retinoblastoma protein in cellular response to nutlin-3.	RB1 MDM2	4.28e-05	3	132	2	19648117
Pubmed	MDMX exerts its oncogenic activity via suppression of retinoblastoma protein.	RB1 MDM2	4.28e-05	3	132	2	25703327
Pubmed	Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy.	FLT1 DMD	4.28e-05	3	132	2	31877123
Pubmed	KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.	RB1 MKI67	4.28e-05	3	132	2	34724040
Pubmed	Mdm2 and PCAF increase Chk2 ubiquitination and degradation independently of their intrinsic E3 ligase activities.	MDM2 KAT2B	4.28e-05	3	132	2	19176998
Pubmed	RB regulates the stability and the apoptotic function of p53 via MDM2.	RB1 MDM2	4.28e-05	3	132	2	10078201
Pubmed	E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.	APC HUWE1	4.28e-05	3	132	2	28137882
Pubmed	Biomarkers distinguishing mammary fibroepithelial neoplasms: a tissue microarray study.	RB1 MKI67	4.28e-05	3	132	2	25003838
Pubmed	Interaction of the HPV E7 proteins with the pCAF acetyltransferase.	RB1 KAT2B	4.28e-05	3	132	2	12813456
Pubmed	Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1.	CYTH1 ITGAM	4.28e-05	3	132	2	15778383
Pubmed	Effects of MdmX on Mdm2-mediated downregulation of pRB.	RB1 MDM2	4.28e-05	3	132	2	16510145
Pubmed	Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner.	RB1 MDM2	4.28e-05	3	132	2	16343421
Pubmed	Expression of pRb, Ki67 and HER 2/neu in gastric carcinomas: Relation to different histopathological grades and stages.	RB1 MKI67	4.28e-05	3	132	2	28965621
Pubmed	Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19.	KRT8 DMD	4.28e-05	3	132	2	16000376
Pubmed	MDM2 mediates p300/CREB-binding protein-associated factor ubiquitination and degradation.	MDM2 KAT2B	4.28e-05	3	132	2	14769800
Pubmed	Genotypic interaction and gender specificity of common genetic variants in the p53/mdm2 network in Crohn's disease.	MDM2 NOD2	4.28e-05	3	132	2	20110711
Pubmed	Protein kinase Cδ differentially regulates cAMP-dependent translocation of NTCP and MRP2 to the plasma membrane.	SLC10A1 ABCC2	4.28e-05	3	132	2	22744337
Pubmed	Dampening of death pathways by schnurri-2 is essential for T-cell development.	HIVEP2 HIVEP3	4.28e-05	3	132	2	21475200
Pubmed	MDM2--master regulator of the p53 tumor suppressor protein.	RB1 MDM2	4.28e-05	3	132	2	10721693
Pubmed	Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.	RB1 APC	4.28e-05	3	132	2	18832169
Pubmed	The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth.	RB1 MDM2	4.28e-05	3	132	2	15485814
Pubmed	DNA-damage-responsive acetylation of pRb regulates binding to E2F-1.	RB1 MDM2	4.28e-05	3	132	2	16374512
Pubmed	MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.	RB1 MDM2	4.28e-05	3	132	2	16337594
Pubmed	Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.	MYH9 MEN1	4.28e-05	3	132	2	14508515
Pubmed	HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator.	RB1 MDM2	4.28e-05	3	132	2	24823443
Pubmed	ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice.	APC ZFP82	4.28e-05	3	132	2	34615997
Pubmed	Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.	KRT8 APC MKI67	4.95e-05	19	132	3	17002498
Pubmed	VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm.	SEMA3F SEMA3C FLT1	5.81e-05	20	132	3	21658587
Pubmed	Bioinformatics and cellular signaling.	CCP110 CYTH1 MDM2 PRPF40A AKAP13 ANAPC7	7.17e-05	182	132	6	15102471
Pubmed	Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population.	HUWE1 MKI67	8.54e-05	4	132	2	33581058
Pubmed	Nucleotide oligomerization domain-2 (NOD2)-induced uveitis: dependence on IFN-gamma.	ITGAM NOD2	8.54e-05	4	132	2	19098321
Pubmed	Relationship of Ki67, TP53, MDM-2 and BCL-2 expressions with WHO 1973 and WHO/ISUP grades, tumor category and overall patient survival in urothelial tumors of the bladder.	MDM2 MKI67	8.54e-05	4	132	2	18572327
Pubmed	Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells.	RB1 MDM2	8.54e-05	4	132	2	18332869
Pubmed	Upper aerodigestive tract squamous dysplasia: correlation with p16, p53, pRb, and Ki-67 expression.	RB1 MKI67	8.54e-05	4	132	2	16948516
Pubmed	SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle.	MDM2 KAT2B	8.54e-05	4	132	2	32404984
Pubmed	Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.	RB1 MKI67	8.54e-05	4	132	2	17442359
Pubmed	Molecular characterisation of breast cancer patients at high and low recurrence risk.	KRT8 RB1	8.54e-05	4	132	2	18236071
Pubmed	Autoinflammatory genes and susceptibility to psoriatic juvenile idiopathic arthritis.	PSTPIP1 NOD2	8.54e-05	4	132	2	18576390
Pubmed	Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice.	SYCP3 LHCGR	8.54e-05	4	132	2	12032072
Pubmed	Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.	APC HUWE1	8.54e-05	4	132	2	27184401
Pubmed	B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains.	DOCK2 NOD2	8.54e-05	4	132	2	30012848
Pubmed	The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis.	SLC10A1 ABCC2	8.54e-05	4	132	2	23125159
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	8.54e-05	4	132	2	32830538
Pubmed	Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation.	RB1 MDM2	8.54e-05	4	132	2	15577944
Pubmed	The metastatic behavior of osteosarcoma by gene expression and cytogenetic analyses.	RB1 MDM2	8.54e-05	4	132	2	23845465
Pubmed	Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53.	RB1 MDM2	8.54e-05	4	132	2	28068628
Cytoband	16p12.3	CCP110 VPS35L ACSM2A ACSM2B	2.83e-06	34	132	4	16p12.3
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CUL2 SEMA3C LIMA1 RAD18 TRIM2 IQGAP2 APC RFC1 BPTF TAOK3 PLXNC1 MKI67 ETAA1 TASOR	4.56e-06	656	129	14	M18979
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	MOGAT1 CYTH1 SLC1A1 GRAMD1B CTNNA3 PLEKHA5 AKAP13 DMD ABCC2 ACSM2A ACSM2B	7.18e-06	417	129	11	M39224
Coexpression	FAN_EMBRYONIC_CTX_OPC	BRINP3 LIMA1 PLPPR1 SLC1A1 TAOK3	7.63e-06	55	129	5	M39038
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CUL2 SEMA3C TRIM2 HIVEP2 RB1 CYTH1 APC TOGARAM1 BPTF TAOK3 ZNF451 AKAP13 DMD TASOR ATP2B1	2.13e-05	856	129	15	M4500
Coexpression	YAGI_AML_WITH_INV_16_TRANSLOCATION	FLT1 WEE1 CYTH1 HLX PRPF40A SLC25A40 AKAP13 DMD ABCC2 ATP2B1	3.78e-05	411	129	10	M1047
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	IQGAP2 RB1 WEE1 SNX30 KLRF1 PLEKHA5 AKAP13	5.80e-05	198	129	7	M6511
Coexpression	GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN	IQGAP2 WEE1 NOD2 PLXNC1 DIAPH2 AMMECR1 ATP2B1	5.80e-05	198	129	7	M3119
Coexpression	GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP	FLT1 MEN1 ARPC2 ROS1 DMD ABCC2 TAF10	5.99e-05	199	129	7	M8354
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	MYH9 CYTH1 SNX30 TAOK3 AKAP13 ATP2B1 MCOLN3	6.18e-05	200	129	7	M9463
Coexpression	HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2	KRT8 MDM2 MKI67	7.53e-05	17	129	3	M9940
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 CYTH1 PSTPIP1 GRAMD1B SLFN12L KAT2B CD48	9.30e-08	189	131	8	b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 CYTH1 PSTPIP1 GRAMD1B SLFN12L KAT2B CD48	9.30e-08	189	131	8	823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 CYTH1 PSTPIP1 GRAMD1B SLFN12L KAT2B CD48	9.30e-08	189	131	8	47c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MOGAT1 UGT3A1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	9.95e-07	178	131	7	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLPPR1 SLC1A1 GRAMD1B PLEKHA5 ABCC2 ACSM2A ACSM2B	1.20e-06	183	131	7	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK2 SEMA3C LIMA1 PLPPR1 TRIM36 ACSM2B	1.24e-06	116	131	6	605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 NEB ARFGEF3 DISP3 ROS1 DMD DNAH11	1.24e-06	184	131	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 NEB ARFGEF3 DISP3 ROS1 DMD DNAH11	1.24e-06	184	131	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 NEB ARFGEF3 DISP3 ROS1 DMD DNAH11	1.24e-06	184	131	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.29e-06	185	131	7	45890fa81c65a48f4fdec164a4c8d0e2831243c0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.29e-06	185	131	7	585bcfdff85bf43f5aa4cd1b39f7dcf1c78d7b02
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	UGT3A1 PLPPR1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.38e-06	187	131	7	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	IQGAP2 HUWE1 BPTF KAT2B TAOK3 AKAP13 TAF10	1.89e-06	196	131	7	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	TRIM2 HIVEP2 APC PGM2L1 ARFGEF3 GUCY1A2 ATP2B1	2.09e-06	199	131	7	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	TRIM2 HIVEP2 APC PGM2L1 ARFGEF3 GUCY1A2 ATP2B1	2.09e-06	199	131	7	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	LIMA1 MYH9 HIVEP2 PGM2L1 MKI67 ANKRD18A TASOR	2.09e-06	199	131	7	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT8 LIMA1 TRIM2 TSGA10 MDM2 ARFGEF3 PLEKHA5	2.16e-06	200	131	7	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer\|World / Primary Cells by Cluster	HIVEP2 PCDH11Y PGM2L1 ARPC2 ARFGEF3 GUCY1A2 ATP2B1	2.16e-06	200	131	7	db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21\|World / Primary Cells by Cluster	HIVEP2 PCDH11Y PGM2L1 ARPC2 ARFGEF3 GUCY1A2 ATP2B1	2.16e-06	200	131	7	30a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 IQGAP2 CCDC168 ITGAM SLFN12L CD48	7.69e-06	159	131	6	bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell	facs-MAT-Fat-3m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 IQGAP2 ITGAM PTCHD1 CD48 DNA2	9.18e-06	164	131	6	b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT1 NUP210L TAOK2 LRRC37A ETAA1 ZFP82	1.05e-05	168	131	6	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 FAM220A PSTPIP1 MKI67 CD48 DNA2	1.24e-05	173	131	6	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 GRAMD1B SNX30 ABCC2 ACSM2A ACSM2B	1.24e-05	173	131	6	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.33e-05	175	131	6	2f43883d7c89f09b0579a390a7431f1f9b832582
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.33e-05	175	131	6	da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 IQGAP2 GRAMD1B ABCC2 ACSM2A ACSM2B	1.37e-05	176	131	6	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	Control-Myeloid-Monocytes,_Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 PSTPIP1 ITGAM NOD2 PLXNC1 CD48	1.51e-05	179	131	6	a79a244bf8ecc333d034b2eb2de554d3310ca6de
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 PSTPIP1 ITGAM NOD2 PLXNC1 CD48	1.51e-05	179	131	6	c4ff8b191ed0f6dc2dd784869f6f2c62e170a7db
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 GRAMD1B SNX30 ABCC2 ACSM2A ACSM2B	1.56e-05	180	131	6	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRAMD1B SNX30 PLEKHA5 ABCC2 ACSM2A ACSM2B	1.56e-05	180	131	6	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.56e-05	180	131	6	bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 PSTPIP1 ITGAM SLFN12L KLRF1 CD48	1.56e-05	180	131	6	c62417f205bcbf3b212ae177f63562ec6467c855
ToppCell	Control-Myeloid\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 PSTPIP1 ITGAM NOD2 PLXNC1 CD48	1.61e-05	181	131	6	25170e5285996cc80337d5f86a0255569861ae77
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	UGT3A1 PLPPR1 SLC1A1 ABCC2 ACSM2A ACSM2B	1.61e-05	181	131	6	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	MOGAT1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.76e-05	184	131	6	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.88e-05	186	131	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRAMD1B SNX30 PLEKHA5 ABCC2 ACSM2A ACSM2B	1.88e-05	186	131	6	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.93e-05	187	131	6	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 GRAMD1B SNX30 ABCC2 ACSM2A ACSM2B	1.93e-05	187	131	6	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 GRAMD1B SNX30 ABCC2 ACSM2A ACSM2B	1.93e-05	187	131	6	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	IQGAP2 PLPPR1 PLXNC1 PRKD1 DMD ABCC2	1.93e-05	187	131	6	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	MOGAT1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.93e-05	187	131	6	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 SLC1A1 GRAMD1B ABCC2 ACSM2A ACSM2B	1.93e-05	187	131	6	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 IQGAP2 PSTPIP1 ITGAM NOD2 ATP2B1	2.11e-05	190	131	6	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	COVID-19-kidney-NK\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK2 IQGAP2 PSTPIP1 SLFN12L KLRF1 CD48	2.11e-05	190	131	6	e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 SNX30 PLEKHA5 ABCC2 ACSM2A ACSM2B	2.18e-05	191	131	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC1A1 SNX30 PLEKHA5 ABCC2 ACSM2A ACSM2B	2.18e-05	191	131	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	DOCK2 FLT1 ITGAM NOD2 PLXNC1 CD48	2.18e-05	191	131	6	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	3'_v3-bone_marrow\|World / Manually curated celltypes from each tissue	IQGAP2 HLX ITGAM ARPC2 SLFN12L KLRF1	2.18e-05	191	131	6	7b759831f1b1c8575c31f67d0d9eb11c6a833cf3
ToppCell	CTRL-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	IQGAP2 PSTPIP1 GRAMD1B SLFN12L KAT2B PLEKHA5	2.18e-05	191	131	6	32381d353e40bce77a5b63c7bdbe360d27327d86
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK2 IQGAP2 SLFN12L KAT2B KLRF1 MKI67	2.18e-05	191	131	6	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C LIMA1 PLPPR1 TRIM36 ACSM2B	2.21e-05	114	131	5	9f0c8dfd740d50448a6c91a00e7bae4dfc9b3302
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 IQGAP2 NOD2 PLXNC1 CD48 ATP2B1	2.24e-05	192	131	6	5417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCell	COPD-Lymphoid\|COPD / Disease state, Lineage and Cell class	MYH9 IQGAP2 NAP1L4 SLFN12L KAT2B KLRF1	2.24e-05	192	131	6	064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCell	Control-Myeloid-cMonocyte\|Control / Disease state, Lineage and Cell class	FLT1 PSTPIP1 ITGAM PLXNC1 CD48 ATP2B1	2.24e-05	192	131	6	ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLPPR1 SLC1A1 GRAMD1B PLEKHA5 ACSM2A ACSM2B	2.31e-05	193	131	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 WEE1 PGM2L1 CCDC178 HIVEP3 PRKD1	2.31e-05	193	131	6	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 WEE1 PGM2L1 CCDC178 HIVEP3 PRKD1	2.31e-05	193	131	6	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 IQGAP2 PSTPIP1 ITGAM SLFN12L PLXNC1	2.38e-05	194	131	6	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	BRINP3 MYH9 DNAI3 CTNNA3 DMD MCOLN3	2.38e-05	194	131	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	DOCK2 IQGAP2 PSTPIP1 GRAMD1B SLFN12L MKI67	2.38e-05	194	131	6	2a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	IQGAP2 HUWE1 KAT2B TAOK3 AKAP13 TAF10	2.45e-05	195	131	6	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	CCP110 NSD2 KAT2B MKI67 DIAPH2 TASOR	2.52e-05	196	131	6	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MDM2 HIVEP3 KLRF1 ETAA1 CD48 AKAP13	2.52e-05	196	131	6	c57a95f8b4d8d6334f269d3c16246684f4222a3e
ToppCell	proximal-Hematologic-Interstitial_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DOCK2 CYTL1 ITGAM GRAMD1B MRO TRIM36	2.52e-05	196	131	6	b6a858c43fef42cd724d56c8283e954bcb546106
ToppCell	proximal-3-Hematologic-Interstitial_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DOCK2 CYTL1 ITGAM GRAMD1B MRO TRIM36	2.52e-05	196	131	6	d8c9cb86233470c3044865ad05ea202e294d80bf
ToppCell	proximal-Hematologic-Interstitial_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DOCK2 CYTL1 ITGAM GRAMD1B MRO TRIM36	2.52e-05	196	131	6	9d4d8ffe9d30de7d1dc33d261bc2aaf4189ad86c
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CCDC60 KRT8 TRIM2 ARFGEF3 PLEKHA5 DNAH11	2.52e-05	196	131	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area\|World / Primary Cells by Cluster	PCDH11Y PGM2L1 PLEKHA5 DMD ATP2B1 GABRA5	2.59e-05	197	131	6	79b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 IQGAP2 CYTH1 ITGAM TAOK3 PLXNC1	2.59e-05	197	131	6	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	KRT8 TRIM2 PGM2L1 ARFGEF3 PLEKHA5 DNAH11	2.59e-05	197	131	6	272c7f4e582ef57564450540242b0db766b78328
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33\|World / Primary Cells by Cluster	PCDH11Y PGM2L1 PLEKHA5 DMD ATP2B1 GABRA5	2.59e-05	197	131	6	d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	DOCK2 IQGAP2 ITGAM GRAMD1B TAOK3 PLXNC1	2.59e-05	197	131	6	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 CYTH1 PSTPIP1 ITGAM SLFN12L CD48	2.59e-05	197	131	6	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Clrn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C BRINP3 LIMA1 TEX15 PLPPR1	2.61e-05	118	131	5	702548d8187d54e8814375e5ae7609631fc71d5f
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 CYTH1 PSTPIP1 ITGAM NOD2 PLXNC1	2.67e-05	198	131	6	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	DOCK2 IQGAP2 CYTH1 ITGAM GRAMD1B ATP2B1	2.67e-05	198	131	6	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 CCDC168 PSTPIP1 ITGAM SLFN12L KLRF1	2.74e-05	199	131	6	598937913fe1f12d741fa49e23ae195a7be5cbe3
ToppCell	(4)_Endothelial_cells-(4)_Blood_vessel\|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	FLT1 LIMA1 MYH9 CYTH1 CYTL1 AKAP13	2.74e-05	199	131	6	e24d70e79f25cdd3300bf5e2322713355264d4c5
ToppCell	Control_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK2 PSTPIP1 ITGAM ARPC2 KLRF1 CD48	2.74e-05	199	131	6	2d7ebb9642f6fe0afd5e3fdc711ded54b73acd11
ToppCell	LPS_IL1RA-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DOCK2 IQGAP2 PSTPIP1 ARPC2 KLRF1 CD48	2.74e-05	199	131	6	0c743e4e88cbd2ca72e5161ca22a3e974b26f9b4
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	IQGAP2 RB1 WEE1 BPTF DMD TAF10	2.74e-05	199	131	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HLX PSTPIP1 ITGAM PLXNC1 CD48 ATP2B1	2.82e-05	200	131	6	47a3fd432c35958c5d478d34f5e0355e39ed0aba
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C LIMA1 PLPPR1 DISP3 PRKD1	2.94e-05	121	131	5	7f2057367777c6c92f596054cbc5fe567d079fbc
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Nptx2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C CCDC178 PLPPR1 PRKD1 TRIM36	3.06e-05	122	131	5	1720756e0b3e8db14a9ccabe83f9b41689a4f754
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C CCDC178 PLPPR1 PRKD1 TRIM36	4.62e-05	133	131	5	840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	FLT1 PCDH11Y TEX15 ADGRG4 CTNNA3	5.70e-05	139	131	5	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C BRINP3 LIMA1 PLPPR1 TRIM36	6.31e-05	142	131	5	ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCell	15-Trachea-Immune-Immune\|Trachea / Age, Tissue, Lineage and Cell class	DOCK2 PSTPIP1 MKI67 CD48 TRIM36	7.20e-05	146	131	5	ca722a89c6601e78f253d9484d01931f26161820
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 ITGAM ARPC2 CD48 DNA2	7.68e-05	148	131	5	31a7c2b20970070b14d2b955020320a6f99db547
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3C BRINP3 LIMA1 TEX15 PLPPR1	7.92e-05	149	131	5	5293c50b3fb41b1edaf9a97354899bd13770078c
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7\|TCGA-Bladder / Sample_Type by Project: Shred V9	DOCK2 HLX CYTL1 HIVEP3 MRO	8.18e-05	150	131	5	3ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 ITGAM ARPC2 CD48 DNA2	8.71e-05	152	131	5	27718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LIMA1 TRIM2 PCDH11Y PTCHD1 DMD	8.71e-05	152	131	5	eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell	facs-Brain_Myeloid-Cerebellum\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP2 PSTPIP1 LHCGR PTCHD1 DNA2	9.84e-05	156	131	5	28c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCell	E15.5-Hematopoietic\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DOCK2 FAM220A PSTPIP1 ITGAM CD48	1.01e-04	157	131	5	6315aef4b9bf673069d43a730d4e940011509ac1
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HLX CCDC178 CTNNA3 CEP41 DMD	1.01e-04	157	131	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	E17.5-Hematopoietic-Immune-immune_cell_unspecified\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DOCK2 PSTPIP1 ITGAM ARPC2 CD48	1.14e-04	161	131	5	30741ca6548db2dfb5cf1faecf0d7412c91d0077
ToppCell	E17.5-Hematopoietic-Immune\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DOCK2 PSTPIP1 ITGAM ARPC2 CD48	1.14e-04	161	131	5	e3ff08d0b9c686253556c56ee88648206751ef2b
Drug	Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SEMA3F RB1 APC HUWE1 MDM2 TAOK2 KAT2B PLXNC1 CCDC87	1.90e-06	197	129	9	6274_UP
Disease	X-21319 measurement	ACSM2A ACSM2B	1.81e-05	2	126	2	EFO_0800807
Disease	Autism Spectrum Disorders	NSUN2 SLC1A1 PTCHD1 CEP41 GABRA5	3.27e-05	85	126	5	C1510586
Disease	X-11478 measurement	ACSM2A ACSM2B	5.41e-05	3	126	2	EFO_0021242
Disease	Mammary Carcinoma, Human	KRT8 FLT1 MYH9 RB1 NSD2 LRRC37A2 MDM2 LRRC37A GUCY1A2 MKI67	8.91e-05	525	126	10	C4704874
Disease	Mammary Neoplasms, Human	KRT8 FLT1 MYH9 RB1 NSD2 LRRC37A2 MDM2 LRRC37A GUCY1A2 MKI67	8.91e-05	525	126	10	C1257931
Disease	Mammary Neoplasms	KRT8 FLT1 MYH9 RB1 NSD2 LRRC37A2 MDM2 LRRC37A GUCY1A2 MKI67	9.19e-05	527	126	10	C1458155
Disease	Acne Vulgaris	PSTPIP1 NOD2	1.08e-04	4	126	2	C0001144
Disease	Acne	PSTPIP1 NOD2	1.08e-04	4	126	2	C0702166
Disease	Pyoderma Gangrenosum	PSTPIP1 NOD2	1.08e-04	4	126	2	C0085652
Disease	Breast Carcinoma	KRT8 FLT1 MYH9 RB1 NSD2 LRRC37A2 MDM2 LRRC37A GUCY1A2 MKI67	1.09e-04	538	126	10	C0678222
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	1.79e-04	5	126	2	EFO_0800378
Disease	GlcNAc sulfate conjugate of C21H34O2 steroid measurement	UGT3A1 MRO	2.68e-04	6	126	2	EFO_0800663
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	2.68e-04	6	126	2	EFO_0800106
Disease	indolepropionate measurement	DNA2 ACSM2A	2.68e-04	6	126	2	EFO_0021016
Disease	eosinophil percentage of leukocytes	CUL2 HIVEP2 NAP1L4 HLX PLPPR1 HIVEP3 BPTF SLFN12L MRO PLXNC1 AKAP13	3.66e-04	746	126	11	EFO_0007991
Disease	Hidradenitis Suppurativa	PSTPIP1 NOD2	3.75e-04	7	126	2	C0162836
Disease	Inflammatory Bowel Diseases	CUL2 APC NOD2	4.50e-04	35	126	3	C0021390
Disease	pneumococcal meningitis	MRO ROS1	4.98e-04	8	126	2	EFO_1001114
Disease	airway imaging measurement	ABCA12 HIVEP3 CCDC87	5.75e-04	38	126	3	EFO_0007627
Disease	metabolite measurement	SEMA3C FMO4 UGT3A1 MCCC1 BPTF SLC10A1 DMD ABCC2 ACSM2A	6.92e-04	560	126	9	EFO_0004725
Disease	Pancreatic Neoplasm	RB1 APC MEN1 ETAA1	9.06e-04	100	126	4	C0030297
Disease	Generalized seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0234533
Disease	Clonic Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0234535
Disease	Convulsive Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0751494
Disease	Seizures, Sensory	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0751496
Disease	Non-epileptic convulsion	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0751056
Disease	Atonic Absence Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0751123
Disease	Complex partial seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0149958
Disease	Single Seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0751110
Disease	Nonepileptic Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C3495874
Disease	Visual seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0270824
Disease	Epileptic drop attack	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0270846
Disease	Vertiginous seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0422855
Disease	Gustatory seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0422854
Disease	Seizures, Somatosensory	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0422850
Disease	Olfactory seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0422853
Disease	Seizures, Auditory	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0422852
Disease	Generalized Absence Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C4505436
Disease	Jacksonian Seizure	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C0022333
Disease	Epileptic Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.40e-04	101	126	4	C4317109
Disease	pregnenediol disulfate (C21H34O8S2) measurement	UGT3A1 ABCC2	9.70e-04	11	126	2	EFO_0800279
Disease	Absence Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.75e-04	102	126	4	C4316903
Disease	Convulsions	PLPPR1 SLC1A1 ABCC2 GABRA5	9.75e-04	102	126	4	C4048158
Disease	Tonic Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	9.75e-04	102	126	4	C0270844
Disease	Malignant neoplasm of pancreas	RB1 APC MEN1 ETAA1	9.75e-04	102	126	4	C0346647
Disease	Seizures, Focal	PLPPR1 SLC1A1 ABCC2 GABRA5	1.05e-03	104	126	4	C0751495
Disease	Myoclonic Seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	1.05e-03	104	126	4	C4317123
Disease	Tonic - clonic seizures	PLPPR1 SLC1A1 ABCC2 GABRA5	1.05e-03	104	126	4	C0494475
Disease	AL amyloidosis	GRAMD1B DNAH11	1.16e-03	12	126	2	MONDO_0019438
Disease	Colorectal Neoplasms	ABCA12 APC GUCY1A2 MKI67 PRKD1 ABCC2	1.25e-03	277	126	6	C0009404
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP2 HIVEP3	1.37e-03	13	126	2	DOID:0050787 (implicated_via_orthology)
Disease	breast cancer (biomarker_via_orthology)	FLT1 MDM2	1.37e-03	13	126	2	DOID:1612 (biomarker_via_orthology)
Disease	Mental Retardation, X-Linked Nonsyndromic	HUWE1 PTCHD1	1.37e-03	13	126	2	C3501611
Disease	Carcinoma, Granular Cell	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0205644
Disease	Adenocarcinoma, Tubular	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0205642
Disease	Carcinoma, Cribriform	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0205643
Disease	Adenocarcinoma, Basal Cell	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0205641
Disease	Adenocarcinoma	KRT8 APC MKI67 PRKD1	1.57e-03	116	126	4	C0001418
Disease	beta-hydroxyisovalerate measurement	MCCC1 ACSM2B	1.59e-03	14	126	2	EFO_0800125
Disease	response to platinum based chemotherapy, magnesium measurement	GUCY1A2 PRKD1	1.83e-03	15	126	2	EFO_0004647, EFO_0004845
Disease	pancreatic ductal carcinoma (is_implicated_in)	MDM2 MEN1	2.09e-03	16	126	2	DOID:3587 (is_implicated_in)
Disease	central nervous system disease (implicated_via_orthology)	TAOK2 TAOK3	2.09e-03	16	126	2	DOID:331 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	KRT8 FLT1 MYH9 RB1 NSD2 LRRC37A2 MDM2 LHCGR LRRC37A GUCY1A2 MKI67 DMD	2.21e-03	1074	126	12	C0006142
Disease	graft-versus-host disease (is_implicated_in)	NOD2 MKI67	2.36e-03	17	126	2	DOID:0081267 (is_implicated_in)
Disease	Adrenocortical carcinoma	RB1 MEN1	2.65e-03	18	126	2	C0206686
Disease	inosine measurement	CTNNA3 DMD	2.95e-03	19	126	2	EFO_0010503
Disease	cerebral infarction (is_marker_for)	BRINP3 ITGAM	2.95e-03	19	126	2	DOID:3526 (is_marker_for)
Disease	interstitial lung disease	PLPPR1 CTNNA3 AKAP13	2.98e-03	67	126	3	EFO_0004244
Disease	Colorectal Carcinoma	ABCA12 APC HIVEP3 GUCY1A2 MKI67 ETAA1 PRKD1 DMD ABCC2	3.24e-03	702	126	9	C0009402
Disease	treatment resistant depression, response to antidepressant	HIVEP3 PTCHD1	3.60e-03	21	126	2	EFO_0009854, GO_0036276
Disease	chronic myeloid leukemia (is_implicated_in)	MDM2 ABCC2	3.60e-03	21	126	2	DOID:8552 (is_implicated_in)
Disease	Sarcoma	RB1 MDM2	3.60e-03	21	126	2	C1261473
Disease	muscular dystrophy (implicated_via_orthology)	TRIM2 DMD	3.60e-03	21	126	2	DOID:9884 (implicated_via_orthology)
Disease	in situ carcinoma (is_marker_for)	RB1 MKI67	3.60e-03	21	126	2	DOID:8719 (is_marker_for)
Disease	cholangiocarcinoma (is_implicated_in)	APC ABCC2	3.95e-03	22	126	2	DOID:4947 (is_implicated_in)
Disease	serum IgM measurement	GRAMD1B PRKD1	3.95e-03	22	126	2	EFO_0004993
Disease	intellectual disability (implicated_via_orthology)	HIVEP2 RB1 NSUN2	4.10e-03	75	126	3	DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKVRTKKTSDSKYPM	C2orf16	1276	Q68DN1
TLKSNKYKSSLVHMI	BRINP3	536	Q76B58
VVTYVAMLAKQSTSK	DISP3	426	Q9P2K9
VISTKLFTEKQRMKY	ANKRD18A	921	Q8IVF6
SISKSKMVKYLLDNR	ANKRD34C	61	P0C6C1
RKMTSLLEKTSLTNY	ADGRG4	1796	Q8IZF6
IKYTIRMSLKTAQTT	ABCA12	981	Q86UK0
REKLKSMTSRDNYKA	ALKBH5	11	Q6P6C2
KSTDILYRLQMSKAK	ACSM2A	141	Q08AH3
DKTKVMVSISLKFYK	ARPC2	51	O15144
SKQTIEFKKMLKSTS	FAM220A	221	Q7Z4H9
FQAFVKKKMSSSVVR	AKAP13	2121	Q12802
IKSRLDTGNSMTKYT	CEP41	26	Q9BYV8
LKMVKILTTKQSSYF	DNAH11	301	Q96DT5
MSKKAPSEISRKYQS	DMD	1006	P11532
KDQVDMTIKYSSKAR	CCDC87	696	Q9NVE4
KMTSFTKTAREQYEK	DIAPH2	946	O60879
ESTKQITYMISRKRS	DNAI3	176	Q8IWG1
SMTVSKEYSTRDKVK	BPTF	1801	Q12830
YTFNSVRKSMSTVLK	ATP2B1	576	P20020
KTATVRETQTMYKAS	GRAMD1B	441	Q3KR37
AYKEMQTTLKSSERS	CCDC60	336	Q8IWA6
STKVDNAMSRLLKKY	RB1	141	P06400
YKKIAGMSQKTVTIT	RAD18	361	Q9NS91
MSIRVTQKSYKVSTS	KRT8	1	P05787
QMKKQKVSTPSDYTL	MEN1	591	O00255
RTTEGKKRQLYMVSK	NSUN2	551	Q08J23
YTMALQQKKALSKTS	ANAPC7	66	Q9UJX3
LVSVSKKSVSYMVSK	MOGAT1	161	Q96PD6
LSKKKTISYTSCMTQ	OR4D11	86	Q8NGI4
AVMDRVQKSKLSLYK	PSTPIP1	121	O43586
FTNSVLTKTYKMKSE	NAP1L4	216	Q99733
MKVLQARKNYTSTEL	LRRC37A3	1071	O60309
QVKMRKRYSVDKTLS	PRKD1	821	Q15139
STVRKVNNKTLYSSM	LHCGR	306	P22888
AVLTKDTMPQTYKRK	HLX	261	Q14774
MKVLQARKNYTSTEL	LRRC37A2	1071	A6NM11
MKVLQARKNYTSTEL	LRRC37A	1071	A6NMS7
SIKDRMAKYQAAVSK	LIMA1	266	Q9UHB6
KRTAKMIPTTTKNNY	SLC24A1	116	O60721
ADVKNLMSYVVTKTK	LETMD1	51	Q6P1Q0
LMSYVVTKTKAINGK	LETMD1	56	Q6P1Q0
KTMSERLKNRYYVSK	KAT2B	771	Q92831
SILKMEIQAKSLTSY	MCOLN3	356	Q8TDD5
ATKSKTMIFYAKINE	CCDC178	656	Q5BJE1
VKEMYLTKLLSTKVA	PLXNC1	1346	O60486
NKDVKYSMRKLSSHI	OR4K3	291	Q96R72
IYTLRNKEVKAAMSK	OR4K15	286	Q8NH41
NKEVKAAMSKLKSRY	OR4K15	291	Q8NH41
NVYMLATTVSSKILK	PGM2L1	381	Q6PCE3
TITDKTARTSSYKAM	NSD2	561	O96028
SSKDGMTRVYKSLVT	FMO4	46	P31512
TKTLAAMQRKPKSYS	INTS2	666	Q9H0H0
FYEMLAARKKKVSST	CYTH1	381	Q15438
KKTYNSISKIDKMSR	GABRA5	416	P31644
KQKRTSMISFFSKVS	MRO	21	Q9BYG7
KVRTAIMASVYKKAL	ABCC2	391	Q92887
EMEGTVKSKYKASIT	MYH9	1796	P35579
SMTNEKTTKVSYRAS	MKI67	1726	P46013
KTTKELDKMISVFYT	OR2D3	281	Q8NGH3
SLKDKARKLYTIMNS	CYTL1	91	Q9NRR1
TAISSKRRAQMTKYL	HUWE1	1596	Q7Z6Z7
DHMNTEITTYKKKLS	ETAA1	781	Q9NY74
IITYMTPKSSKQQEK	OR2D2	256	Q9H210
LENHEKMTSTTRYKK	PRPF40A	471	O75400
TTSVAKIAQYKRKLM	NUP54	366	Q7Z3B4
KTPKDKTKMIYTAAT	SLC10A1	311	Q14973
TVKMSYIASTKIIRI	CTNNA3	821	Q9UI47
RYMTLNVQSKKRSSA	KLRF1	6	Q9NZS2
KKLMTVLKTYLDTSS	DOCK2	711	Q92608
NKIYTMAADKTISKL	ARFGEF3	2011	Q5TH69
TISKLMTEYKKRKQQ	ARFGEF3	2021	Q5TH69
KLEKMYSKTNTSSTI	DEFB112	11	Q30KQ8
SKRTKFKITTSMQKD	CUL2	646	Q13617
ILTSSKQIDKSSMYK	CYP4V2	111	Q6ZWL3
LSAATQKSLDRKKYM	CCP110	911	O43303
SYLSMEKIIQVAKTS	MCCC1	106	Q96RQ3
YAKSTTSKSMIDKLL	CCDC168	2211	Q8NDH2
KEDNSTYIMRVLKKT	CD48	101	P09326
SKIMSLSNKLTYEGK	DNA2	831	P51530
AVMTTAISKNKTKEY	SLC1A1	186	P43005
KFLMSVTKLVESKSY	KRBA2	111	Q6ZNG9
VAIAKDKMGRKYTST	NUP210L	1061	Q5VU65
SKYGKTLSVKVMTDS	PABPC4L	211	P0CB38
NKSLTTTMQFKLVYK	PCDH11Y	86	Q9BZA8
SSSRIKKVSYNIGTM	GUCY1A2	711	P33402
DMKTSLKKVVKETSY	MTCH1	186	Q9NZJ7
KMKTSESSTILVVRY	SPANXA1	41	Q9NS26
VTTMSSAYKTLKEKL	TRIM36	246	Q9NQ86
KSTLSLISIMKYSKA	TRMT44	291	Q8IYL2
SKSKDRKYTLTMEDL	TAF10	186	Q12962
KTMTISSKRQQLYVA	SEMA3F	521	Q13275
ITTMKISSKKQQLYV	SEMA3C	486	Q99985
RLEMYTKASLKTSNQ	SYCP3	91	Q8IZU3
RTKMQSKKFSYVELH	SLC25A40	166	Q8TBP6
SSKLAIMKRKEESSY	RFC1	316	P35251
TVRLFQKSNSKVKMY	PTCHD1	236	Q96NR3
KFNMDKYTDLVTVSK	IQGAP2	1191	Q13576
KLLKSVGAQKDTYTM	MDM2	36	Q00987
MLRNKYKTCTSKTEV	SHOC1	526	Q5VXU9
SHKSRTTVKYTMKTL	SLC9A5	321	Q14940
TIDLYTKMRKQASEK	SLC5A4	406	Q9NY91
SEVVAIKKMSYSGKQ	TAOK2	51	Q9UL54
TSEVVAIKKMSYSGK	TAOK3	46	Q9H2K8
MKKLTYAKETVSSSE	IMPG2	166	Q9BZV3
KKSKTLFSLMQYSEE	ITGAM	181	P11215
ATMYITSTIKTKSSR	PLPPR1	211	Q8TBJ4
EKMKRLSEFIYSKTS	TASOR	1056	Q9UK61
KSTDILYRLQMSKAK	ACSM2B	141	Q68CK6
TIKLTRYRSEKMTLS	AMMECR1	291	Q9Y4X0
NKKVELSRMSSTKSS	APC	2411	P25054
SKRKSMKSSTYEELD	TIGD2	66	Q4W5G0
QSKFSSLKRTMSIKE	ZNF451	421	Q9Y4E5
TLTMKQVIEDKRYKS	UGT3A1	421	Q6NUS8
KTSGSEKKYLRAMQA	RNFT1	26	Q5M7Z0
AKRITITESNMKSRY	WEE1	281	P30291
GMRSQEVTKILSKKY	UBTFL6	131	P0CB48
ADTRTMVKTLEYIKK	VPS35L	926	Q7Z3J2
KYMAKLRTTVSAQSR	NOD2	221	Q9HC29
SSSLYKRDVTSAKVM	SLFN12L	141	Q6IEE8
AMSQKAKETVSTRYT	SARG	246	Q9BW04
ILYSDSMKSVLKKRD	SNX30	331	Q5VWJ9
LRSKQKVSKETYTMA	HIVEP3	1651	Q5T1R4
SAMKYKVSVRASSPK	ROS1	641	P08922
YKSQISTLHKSVVKM	TSGA10	476	Q9BZW7
VKMPSEKVSSYQKRT	ZFP82	141	Q8N141
SVMKDIKNTTQKKYR	UBR3	1421	Q6ZT12
GQVKITSEKMTTYKR	ZFP14	141	Q9HCL3
VSISKSTYNKMRQKR	TOGARAM1	1171	Q9Y4F4
QAEKAKDSVYKRSMT	TEX15	1466	Q9BXT5
VKQKAVKRPASMYST	TRIM2	446	Q9C040
STIASYVTLRKTKKM	PLEKHA5	861	Q9HAU0
RKMKRSSSEIKTDYL	FLT1	781	P17948
SKQKITAEIYTLAAM	HIVEP2	1696	P31629
SKKRVKREPYSTTML	nan	16	Q8N402
MTVLRNQDSTYKKVA	ZNF554	151	Q86TJ5
KVATSKSVQVDYMKT	GLYATL2	116	Q8WU03
VKNTAMFSKKLYTED	NEB	196	P20929