Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	procollagen-proline 3-dioxygenase activity	P3H2 P3H1	9.49e-05	3	113	2	GO:0019797
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in AV node cell action potential	CACNA1C CACNA1G	9.49e-05	3	113	2	GO:0086056
GeneOntologyMolecularFunction	peptidyl-proline 3-dioxygenase activity	P3H2 P3H1	1.89e-04	4	113	2	GO:0031544
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1G	3.14e-04	5	113	2	GO:0086007
Domain	ARM-type_fold	TNPO1 DNAJC13 IPO7 IFT172 LRRK2 ARMCX3 PPP4R3A ATP6V1H CLTC MROH7 XPO7	7.29e-06	339	114	11	IPR016024
Domain	ARM-like	TNPO1 DNAJC13 IPO7 LRRK2 ARMCX3 PPP4R3A ATP6V1H MROH7 XPO7	4.17e-05	270	114	9	IPR011989
Domain	IMPORTIN_B_NT	TNPO1 IPO7 XPO7	7.68e-05	14	114	3	PS50166
Domain	IBN_N	TNPO1 IPO7 XPO7	9.55e-05	15	114	3	PF03810
Domain	IBN_N	TNPO1 IPO7 XPO7	1.17e-04	16	114	3	SM00913
Domain	Importin-beta_N	TNPO1 IPO7 XPO7	1.41e-04	17	114	3	IPR001494
Domain	Channel_four-helix_dom	CACNA1C TPCN1 CATSPER2 CACNA1G	4.05e-04	57	114	4	IPR027359
Domain	-	CACNA1C TPCN1 CATSPER2 CACNA1G	4.05e-04	57	114	4	1.20.120.350
Domain	-	TNPO1 DNAJC13 IPO7 LRRK2 ARMCX3 ATP6V1H MROH7	4.28e-04	222	114	7	1.25.10.10
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	TNPO1 DDX17 IPO7 ELP1 BPTF FUBP1 CLTC USP7 CAPRIN1	8.44e-09	179	114	9	36261009
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	TNPO1 PRUNE2 DDX17 ACACA IPO7 TRMT1 IKBKG ELP1 BCAT1 COPS3 ARMCX3 ZYX PPP4R3A RNF123 ATP6V1H UBE3A P3H1 FUBP1 USP7 SNRPB2 XPO7	1.02e-08	1455	114	21	22863883
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DNAJC13 IPO7 ELP1 EXOC3 ITPRID2 SIX4 ZYX TAB3 PPP4R3A NCOA5 TBC1D10B LONP1 PTPRJ P3H1 CLTC USP7	3.40e-07	1049	114	16	27880917
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DNAJC13 DDX17 ACACA IPO7 ITPRID2 CLTC MROH7 CAPRIN1	3.66e-07	202	114	8	33005030
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	SOX2 TNPO1 RMND5B EPS8 IPO7 COPS3 SLFN5 LONP1 USP7	4.11e-07	282	114	9	23667531
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	DNAJC13 IKBKG ELP1 ZYX TAB3 PPP4R3A EVI5 UBE3A P3H2 USP7	5.10e-07	378	114	10	34315543
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TNPO1 RMND5B NCOA3 CDR2 DNAJC13 DDX17 IFT172 EXOC3 COPS3 ZYX PPP4R3A LONP1 IFT88 OSBPL3 RABGAP1L SNAPC1 SNRPB2	1.48e-06	1321	114	17	27173435
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TNPO1 RMND5B EPS8 DNAJC13 SLC38A4 BCAT1 BPTF OSBPL3 RABGAP1L POLR1B PLCB4	1.68e-06	538	114	11	10512203
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	TNPO1 EFCAB5 DDX17 IPO7 ZYX NCOA5 TBC1D10B LONP1 FUBP1 CLTC USP7 SNRPB2 CAPRIN1	2.65e-06	809	114	13	32129710
Pubmed	Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.	TNPO1 IPO7 XPO7	2.84e-06	9	114	3	11024021
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOA3 DDX17 IPO7 ARHGAP15 ETV5 BCAT1 COPS3 ZYX PPP4R3A BPTF BRCA1 FUBP1 CLTC SNRPB2 CAPRIN1	3.34e-06	1103	114	15	34189442
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	TNPO1 DNAJC13 DDX17 ACACA IPO7 IFT172 ELP1 PPP4R3A LONP1 CLTC USP7	8.48e-06	638	114	11	33239621
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DNAJC13 DDX17 ACACA IPO7 ELP1 EXOC3 COPS3 NAA35 LONP1 UBE3A FUBP1 CLTC USP7 POLR1B PLCG2 CAPRIN1	8.98e-06	1353	114	16	29467282
Pubmed	Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.	SOX2 IFT172 RFX2 IFT88	9.13e-06	40	114	4	32317081
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NCOA3 DNAJC13 ACACA ITPRID2 ZYX PPP4R3A C2CD5 BPTF TBC1D10B FUBP1 CLTC USP7	9.43e-06	774	114	12	15302935
Pubmed	Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.	IFT172 IFT88	1.07e-05	2	114	2	11062270
Pubmed	Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.	P3H2 P3H1	1.07e-05	2	114	2	18487197
Pubmed	Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1.	ACACA BRCA1	1.07e-05	2	114	2	18452305
Pubmed	Structural basis for regulation of human acetyl-CoA carboxylase.	ACACA BRCA1	1.07e-05	2	114	2	29899443
Pubmed	Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex.	ACACA BRCA1	1.07e-05	2	114	2	19061860
Pubmed	DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer.	SOX2 DDX17	1.07e-05	2	114	2	26569340
Pubmed	BRCA1 is a novel regulator of metabolic function in skeletal muscle.	ACACA BRCA1	1.07e-05	2	114	2	24565757
Pubmed	CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation.	IKBKG COPS3	1.07e-05	2	114	2	11418127
Pubmed	Aromatase expression is increased in BRCA1 mutation carriers.	CYP19A1 BRCA1	1.07e-05	2	114	2	19445691
Pubmed	Mutational alterations of TDRD 1, 4 and 9 genes in colorectal cancers.	TDRD9 TDRD1	1.07e-05	2	114	2	32036563
Pubmed	BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.	ACACA BRCA1	1.07e-05	2	114	2	12360400
Pubmed	Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.	UBE3A USP7	1.07e-05	2	114	2	20930542
Pubmed	BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi Jews.	CYP19A1 BRCA1	1.07e-05	2	114	2	19366906
Pubmed	E6AP mediates regulated proteasomal degradation of the nuclear receptor coactivator amplified in breast cancer 1 in immortalized cells.	NCOA3 UBE3A	1.07e-05	2	114	2	16951183
Pubmed	ACCA phosphopeptide recognition by the BRCT repeats of BRCA1.	ACACA BRCA1	1.07e-05	2	114	2	16698035
Pubmed	BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.	ACACA BRCA1	1.07e-05	2	114	2	16326698
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TNPO1 RMND5B EPS8 DNAJC13 SLC38A4 BCAT1 BPTF OSBPL3 RABGAP1L PLCB4	1.13e-05	536	114	10	15840001
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	TEAD2 ABCB5 LRRK2 ETV5 TCEANC EVI5 CATSPER2 SLC35B4 RABGAP1L PLCB4 PPP1R36	1.66e-05	686	114	11	29987050
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	LGMN DDX17 IPO7 CLTC USP7 PLCG2 CAPRIN1 XPO7	1.87e-05	344	114	8	30333137
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TNPO1 DNAJC13 DDX17 ACACA IPO7 ENPP1 ZYX BPTF NAA35 ATP6V1H P3H1 FUBP1 CLTC PLCB4 CAPRIN1	2.27e-05	1297	114	15	33545068
Pubmed	KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.	RNF123 UBAC1	3.19e-05	3	114	2	25860612
Pubmed	circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer.	ACACA CAPRIN1	3.19e-05	3	114	2	36328987
Pubmed	Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.	RNF123 UBAC1	3.19e-05	3	114	2	15531880
Pubmed	Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes.	P3H2 P3H1	3.19e-05	3	114	2	15044469
Pubmed	HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination.	IKBKG USP7	3.19e-05	3	114	2	24832601
Pubmed	T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.	CACNA1C CACNA1G	3.19e-05	3	114	2	31919478
Pubmed	Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.	NCOA3 BRCA1	3.19e-05	3	114	2	14648706
Pubmed	Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene.	NCOA3 BRCA1	3.19e-05	3	114	2	15900600
Pubmed	Polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a meta-analysis of observational studies.	NCOA3 BRCA1	3.19e-05	3	114	2	23483928
Pubmed	The AIB1 gene polyglutamine repeat length polymorphism and the risk of breast cancer development.	NCOA3 BRCA1	3.19e-05	3	114	2	20422428
Pubmed	LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease.	LRRK2 CLTC	3.19e-05	3	114	2	29735704
Pubmed	HSV ICP0 recruits USP7 to modulate TLR-mediated innate response.	IKBKG USP7	3.19e-05	3	114	2	18952891
Pubmed	Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.	CACNA1C CACNA1G	3.19e-05	3	114	2	22133878
Pubmed	TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.	TNPO1 FUBP1	3.19e-05	3	114	2	33987449
Pubmed	Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase.	RNF123 UBAC1	3.19e-05	3	114	2	15746103
Pubmed	Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.	CACNA1C CACNA1G	3.19e-05	3	114	2	37739992
Pubmed	Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues.	P3H2 P3H1	3.19e-05	3	114	2	19652424
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TNPO1 DDX17 IPO7 ELP1 EXOC3 ITPRID2 NCOA5 BPTF LONP1 FUBP1 CLTC SNRPB2 XPO7	3.23e-05	1024	114	13	24711643
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	TNPO1 NCOA3 TAB3 BPTF	3.28e-05	55	114	4	18570454
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	TNPO1 DDX17 IPO7 ITPRID2 BPTF BRCA1 CLTC USP7 CAPRIN1	3.80e-05	494	114	9	26831064
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	TNPO1 CDR2 DNAJC13 DDX17 ZYX FUBP1 CAPRIN1	5.95e-05	298	114	7	30737378
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TNPO1 ACACA IPO7 ELP1 BPTF LONP1 CLTC USP7 CAPRIN1 XPO7	6.01e-05	653	114	10	22586326
Pubmed	CBP/p300 interact with and function as transcriptional coactivators of BRCA1.	NCOA3 BRCA1	6.36e-05	4	114	2	10655477
Pubmed	[Analysis of polymorphisms in genes of insulin receptor substrate-1 and enzymes involved in estrogen biosynthesis and metabolism among breast cancer patients with BRCA1 mutations].	CYP19A1 BRCA1	6.36e-05	4	114	2	19514368
Pubmed	What are those cilia doing in the neural tube?	IFT172 IFT88	6.36e-05	4	114	2	23351466
Pubmed	SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.	NCOA3 USP7	6.36e-05	4	114	2	23388826
Pubmed	Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition.	TEAD2 ZYX	6.36e-05	4	114	2	24554433
Pubmed	Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia.	TDRD9 TDRD1	6.36e-05	4	114	2	32059713
Pubmed	Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1.	TNPO1 IPO7	6.36e-05	4	114	2	16704975
Pubmed	Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP.	LRRK2 TPCN1	6.36e-05	4	114	2	22012985
Pubmed	Regulation of the BRCA1 gene by an SRC3/53BP1 complex.	NCOA3 BRCA1	6.36e-05	4	114	2	21914189
Pubmed	The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.	BRCA1 UBE3A	6.36e-05	4	114	2	12890688
Pubmed	Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.	CACNA1C CACNA1G	6.36e-05	4	114	2	21788606
Pubmed	Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.	BRCA1 USP7	6.36e-05	4	114	2	30894746
Pubmed	Themis2 is not required for B cell development, activation, and antibody responses.	THEMIS2 PLCG2	6.36e-05	4	114	2	24907343
Pubmed	The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.	ACACA IPO7 FUBP1	6.60e-05	24	114	3	24798327
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX2 NCOA3 TEAD2 IKBKG ETV5 SIX4 RFX2 ZYX LDB2 BPTF ZNF844	7.30e-05	808	114	11	20412781
Pubmed	Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.	TNPO1 ACACA IPO7	8.44e-05	26	114	3	23181366
Pubmed	Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.	RNF123 UBAC1	1.06e-04	5	114	2	16227581
Pubmed	Distinct calcium channels regulate responses of primary B lymphocytes to B cell receptor engagement and mechanical stimuli.	TRPC4 PLCG2	1.06e-04	5	114	2	15611229
Pubmed	Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex.	UBE3A USP7	1.06e-04	5	114	2	31492752
Pubmed	Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.	TNPO1 IPO7	1.06e-04	5	114	2	27528606
Pubmed	Combining Homologous Recombination and Phosphopeptide-binding Data to Predict the Impact of BRCA1 BRCT Variants on Cancer Risk.	ACACA BRCA1	1.06e-04	5	114	2	30257991
Pubmed	Multiple pathways contribute to nuclear import of core histones.	TNPO1 IPO7	1.06e-04	5	114	2	11493596
Pubmed	Development of gustatory papillae in the absence of Six1 and Six4.	SOX2 SIX4	1.06e-04	5	114	2	21978088
Pubmed	Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm.	TEAD2 SIX4	1.06e-04	5	114	2	30807574
Pubmed	A novel role for BRCA1 in regulating breast cancer cell spreading and motility.	ETV5 BRCA1	1.06e-04	5	114	2	21282464
Pubmed	MVH in piRNA processing and gene silencing of retrotransposons.	TDRD9 TDRD1	1.06e-04	5	114	2	20439430
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	TNPO1 RMND5B DDX17 PPP4R3A TBC1D10B FUBP1 RABGAP1L CLTC SNRPB2 CAPRIN1 BRWD1	1.11e-04	847	114	11	35235311
Pubmed	Functional proteomics mapping of a human signaling pathway.	RMND5B IKBKG BCAT1 ZYX LDB2 RNF123 UBE3A UBAC1 PLCG2	1.48e-04	591	114	9	15231748
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	SOX2 NCOA3 TEAD2 IKBKG TCEANC RFX2 LDB2 NCOA5 BRCA1 POLR1B SNAPC1	1.50e-04	877	114	11	20211142
Pubmed	Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.	PLCB4 PLCG2	1.58e-04	6	114	2	8739298
Pubmed	International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels.	TPCN1 CATSPER2	1.58e-04	6	114	2	16382101
Pubmed	The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.	LRRK2 MYO1F	1.58e-04	6	114	2	25926623
Pubmed	Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development.	SOX2 IFT88	1.58e-04	6	114	2	28954202
Pubmed	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.	PLCB4 PLCG2	1.58e-04	6	114	2	2841328
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	SOX2 NCOA3 SIX4 BPTF	1.65e-04	83	114	4	28794006
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	TNPO1 ACACA ABCG1	1.74e-04	33	114	3	26296893
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	PNMA1 ACACA TCEANC ZYX BRCA1 UBE3A USP7 CACNA1G CCDC33	1.83e-04	608	114	9	16713569
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	LGMN DDX17 ACACA IPO7 COPS3 PTPRJ P3H1 CLTC CAPRIN1	1.94e-04	613	114	9	22268729
Pubmed	A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.	IKBKG ELP1 TAB3 CLTC POLR1B	2.01e-04	162	114	5	14743216
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	TNPO1 DDX17 ACACA IPO7 ENPP1 CLTC USP7 CAPRIN1	2.02e-04	484	114	8	31995728
Pubmed	Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin.	TNPO1 IPO7	2.21e-04	7	114	2	11682607
Pubmed	Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.	LGMN CLTC	2.21e-04	7	114	2	34018922
Pubmed	Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells.	TRPC4 ZYX	2.21e-04	7	114	2	23233529
Interaction	TRIM33 interactions	SOX2 TNPO1 NCOA3 PNMA1 DDX17 IPO7 ELP1 BPTF BRCA1 FUBP1 CLTC USP7 CAPRIN1	1.42e-06	453	112	13	int:TRIM33
Interaction	FAM133A interactions	RFX2 PPP4R3A NAA35 BRCA1 UBE3A USP7	5.95e-06	81	112	6	int:FAM133A
Interaction	IKBKB interactions	NCOA3 IKBKG ELP1 COPS3 TAB3 BRCA1 FUBP1 CLTC POLR1B	6.19e-06	233	112	9	int:IKBKB
Interaction	TCEANC interactions	PNMA1 IKBKG TCEANC EVI5 BRCA1 OSBPL3 CCDC33	1.67e-05	145	112	7	int:TCEANC
Interaction	LRRC31 interactions	DNAJC13 DDX17 ACACA IPO7 ITPRID2 CLTC MROH7 CAPRIN1	1.92e-05	205	112	8	int:LRRC31
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NCOA3 EPS8 DNAJC13 DDX17 IPO7 C2CD5 EVI5 BPTF ATP6V1H BRCA1 UBE3A FUBP1 RABGAP1L USP7 PLCB4	4.18e-06	856	113	15	M4500
Coexpression	GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP	TDRD9 LRRK2 ANGPTL1 PTPRJ MYO1F PLCB4 PLCG2	6.48e-06	161	113	7	M9446
Coexpression	TRAVAGLINI_LUNG_CILIATED_CELL	SOX2 PRUNE2 PNMA1 IFT172 SLFN5 SIX4 RFX2 DNAH7 EVI5 NAA35 IFT88 OSBPL3 UBAC1 THNSL2 PPP1R36 CCDC33	1.86e-05	1093	113	16	M41649
Coexpression	GSE3982_MAST_CELL_VS_NKCELL_UP	IPO7 ETV5 BCAT1 ITPRID2 EVI5 CLTC CAPRIN1	2.56e-05	199	113	7	M5450
Coexpression	KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN	CDR2 IFT172 NCOA5 LONP1 ABCG1 IFT88 RABGAP1L	2.56e-05	199	113	7	M3028
Coexpression	GSE6875_WT_VS_FOXP3_KO_TREG_UP	NCOA3 CDR2 DNAJC13 ACACA ETV5 MAST1 BRWD1	2.64e-05	200	113	7	M6803
Coexpression	TBK1.DF_DN	NCOA3 CDR2 BPTF TBC1D10B NAA35 P3H2 OSBPL3 BRWD1	3.46e-05	286	113	8	M2864
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	NCOA3 EPS8 DNAJC13 IPO7 C2CD5 EVI5 BPTF BRCA1 UBE3A FUBP1	3.48e-05	466	113	10	M13522
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 PNMA1 RFX2 TAB3 RNF123 UBAC1 CACNA1G	2.63e-07	168	114	7	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 PNMA1 RFX2 TAB3 RNF123 UBAC1 CACNA1G	2.63e-07	168	114	7	a61b39884851384cffd430079040546d125b2b40
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CRISPLD2 CACNA1C EPS8 ARHGAP15 ENPP1 TRPC4 PLCB4	4.86e-07	184	114	7	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PNMA1 CDHR2 FER1L6 GZMA MROH7	3.17e-06	88	114	5	b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PNMA1 CDHR2 FER1L6 GZMA MROH7	3.17e-06	88	114	5	7992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PNMA1 CDHR2 FER1L6 GZMA MROH7	3.17e-06	88	114	5	b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ABCB5 LDB2 LIPM SLCO2A1 CACNA1G PLCB4	5.42e-06	172	114	6	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3F EPS8 ADCY1 ANGPTL1 ATP6V1H PLCG2	6.60e-06	178	114	6	3d6d03bc57062f74ba19fc675dd36b12b6c7115d
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	PRUNE2 CRISPLD2 CACNA1C EPS8 TRPC4 CBLN1	6.81e-06	179	114	6	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CRISPLD2 CACNA1C EPS8 ENPP1 TRPC4 PLCB4	7.26e-06	181	114	6	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGMN NCOA3 STAB2 SLFN5 LDB2 ABCG1	7.49e-06	182	114	6	000ff26c51c6a1ea8770c02722523e55be83b46f
ToppCell	facs-Liver-Liver_non-hepato/SCs_st\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGMN NCOA3 STAB2 SLFN5 LDB2 ABCG1	7.49e-06	182	114	6	b906e6e584ecbe92d3030bbdc4426f244fbe0045
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NCOA3 SLC38A4 ENAM OSBPL3 RABGAP1L PLCG2	8.22e-06	185	114	6	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F RFX2 LDB2 ABCG1 SLCO2A1 PLCG2	8.22e-06	185	114	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8 LRRK2 ETV5 BCAT1 CELSR1 P3H2	8.48e-06	186	114	6	e83718fabb057100835d3357df407f283d23fe16
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 P3H2 OSBPL3 PLCB4	8.74e-06	187	114	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	(7)_DC_1\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SEMA3F LGMN PNMA1 ENPP1 P3H2 SLCO2A1	9.01e-06	188	114	6	832887afa4a54ed80906bc02176d646529c13398
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8 LRRK2 ETV5 BCAT1 CELSR1 P3H2	9.01e-06	188	114	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	EC-Sinusoidal_ECs\|World / Lineage and Cell class	SEMA3F LGMN STAB2 SLFN5 LDB2 SLCO2A1	9.29e-06	189	114	6	9a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 DNAH7 ABCG1 CELSR1	9.29e-06	189	114	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 P3H2 OSBPL3 PLCB4	9.57e-06	190	114	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 P3H2 OSBPL3 PLCB4	9.57e-06	190	114	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F CACNA1C LDB2 ABCG1 SLCO2A1 PLCG2	1.02e-05	192	114	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TNPO1 BPTF ZBED6 CLTC POLR1B CAPRIN1	1.05e-05	193	114	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	THEMIS2 LGMN ARHGAP15 BCAT1 PTPRJ MYO1F	1.08e-05	194	114	6	f09675cd472200363c458952f00d2e41990800ee
ToppCell	Control-Myeloid-MoAM4\|Myeloid / Condition, Lineage and Cell class	LGMN EPS8 ENPP1 ETV5 BCAT1 P3H2	1.08e-05	194	114	6	7ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCell	(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells\|(0)_Normal/No_Treatment / Stress and Cell class	LGMN STAB2 SLFN5 LDB2 SLCO2A1 CLTC	1.11e-05	195	114	6	e8ab3122f81cb22920becd6611cbd9f00db19d50
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA3F TEAD2 LDB2 ABCG1 SLCO2A1 PLCB4	1.11e-05	195	114	6	fde8e7b38b3631109b95ef111c5f6e3f9878cfbd
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCB5 SLFN5 LDB2 SLCO2A1 GZMA PLCB4	1.11e-05	195	114	6	63e132fd6e4318299dd47bbe8ed3bf120efe46dd
ToppCell	Control-Myeloid-MoAM4\|Control / Condition, Lineage and Cell class	LGMN EPS8 ENPP1 ETV5 BCAT1 P3H2	1.11e-05	195	114	6	211a736acbe875bd3c1942c62aaacc9b170ece6d
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	THEMIS2 ARHGAP15 LRRK2 BCAT1 ABCG1 MYO1F	1.11e-05	195	114	6	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	LGMN STAB2 SLFN5 LDB2 SLCO2A1 CLTC	1.11e-05	195	114	6	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LRRK2 ETV5 BCAT1 CELSR1 P3H2 RABGAP1L	1.18e-05	197	114	6	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	SEMA3F EPS8 ITPRID2 SLFN5 LDB2 SLCO2A1	1.25e-05	199	114	6	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1F MROH7 CYP2U1 SGCE SNAPC1	3.25e-05	142	114	5	ae495c8dd733f0fde66bddc281606543f21c0d4b
ToppCell	lung-Type_II_Pneumocytes\|lung / shred on tissue and cell subclass	LRRK2 ETV5 BCAT1 P3H2 RABGAP1L	3.83e-05	147	114	5	8a3039de45b8087f8319e2e37329acf7278219b7
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ABCB5 SIX4 ACOX2 DCLRE1C PPP1R36	4.36e-05	151	114	5	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ABCB5 SIX4 ACOX2 DCLRE1C PPP1R36	4.36e-05	151	114	5	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	LRRK2 SIX4 TDRD1 CELSR1 OSBPL3	4.50e-05	152	114	5	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	PND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	THEMIS2 ARHGAP15 PTPRJ MYO1F PLCG2	5.09e-05	156	114	5	166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCell	PND07-28-samps-Myeloid-Granulocyte\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	THEMIS2 ARHGAP15 PTPRJ MYO1F PLCG2	5.09e-05	156	114	5	5e1c5a7c9293b886920739cf766521df7f69726c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 ADCY1 FER1L6 PTPRJ PLCG2	5.74e-05	160	114	5	174a4ab27114efcc63be36929b80680be3c35c9b
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJC13 IPO7 LRRK2 TAB3 P3H2	6.45e-05	164	114	5	54f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TDRD9 CDHR2 BRCA1 SLITRK6	6.45e-05	84	114	4	db96d45e863d04a9b340c9229576d654dce85a3f
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TDRD9 CDHR2 BRCA1 SLITRK6	6.45e-05	84	114	4	152807da52b50713fc6fed2b2bef5d5762e9c0da
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TDRD9 CDHR2 BRCA1 SLITRK6	6.45e-05	84	114	4	a88bdb8ea8a50df38fb740515d02aa87293e5d25
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 ADCY1 ANGPTL1 PLCG2 PPP1R36	6.64e-05	165	114	5	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	droplet-Lung-nan-18m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH3 SLFN5 PTPRJ MYO1F PLCG2	6.64e-05	165	114	5	e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 BCAT1 BRCA1 LRRTM2 SLITRK6	6.64e-05	165	114	5	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	droplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH3 SLFN5 PTPRJ MYO1F PLCG2	6.64e-05	165	114	5	0fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TEAD2 ABCB5 SIX4 ACOX2 PPP1R36	7.23e-05	168	114	5	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	TEAD2 ABCB5 SIX4 ACOX2 PPP1R36	7.23e-05	168	114	5	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	TNPO1 EFCAB5 TPCN1 NAA35 OSBPL3	7.64e-05	170	114	5	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	PRUNE2 CACNA1C ENPP1 TRPC4 PLCB4	8.30e-05	173	114	5	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	TNPO1 EFCAB5 DDX17 NAA35 OSBPL3	8.30e-05	173	114	5	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 LGMN EPS8 DCLRE1C CLTC	8.76e-05	175	114	5	d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	NCOA3 ARHGAP15 ANGPTL1 RABGAP1L PLCG2	9.24e-05	177	114	5	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 ADCY1 FER1L6 PTPRJ PLCG2	9.24e-05	177	114	5	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEAD2 ITPRID2 LDB2 SLCO2A1 LRRTM2	9.24e-05	177	114	5	16197068260fc062bf8b730a51a199887ea580b9
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP15 ENPP1 ENAM MYO1F PLCG2	9.24e-05	177	114	5	c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell	ICU-NoSEP-Myeloid-cDC1\|ICU-NoSEP / Disease, Lineage and Cell Type	LGMN PNMA1 ENPP1 TDRD1 CLCN4	9.24e-05	177	114	5	33cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCell	3'_v3-Lung-Myeloid_Mac-Erythrophagocytic_macrophages\|Lung / Manually curated celltypes from each tissue	LGMN CDHR2 ABCB5 ETV5 ZBED6	9.49e-05	178	114	5	b63cee443cc1b7416112bf610d7c9d41e4fa37ed
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR2 IFT172 ETV5 PTPRJ PLCG2	9.75e-05	179	114	5	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F LDB2 ABCG1 SLCO2A1 PLCG2	1.00e-04	180	114	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	EPS8 ACACA LRRK2 ETV5 P3H2	1.00e-04	180	114	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CRISPLD2 CACNA1C EPS8 LDB2 PLCB4	1.05e-04	182	114	5	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THEMIS2 ENPP1 ATP6V1H CLTC PLCG2	1.05e-04	182	114	5	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	PRUNE2 CACNA1C TRPC4 P3H2 PLCB4	1.08e-04	183	114	5	818fd886e0188091310825f9145fa53328f2c979
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C SLFN5 LDB2 ABCG1 SLCO2A1	1.08e-04	183	114	5	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 CELSR1 P3H2	1.08e-04	183	114	5	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 CACNA1C TRPC4 RFX2 P3H2	1.08e-04	183	114	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 ETV5 BCAT1 CELSR1 P3H2	1.11e-04	184	114	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 ETV5 BCAT1 CELSR1 P3H2	1.14e-04	185	114	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LGMN ETV5 BCAT1 CELSR1 P3H2	1.14e-04	185	114	5	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	facs-Skin-Anagen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F CELSR1 ATP6V1H LIPM P3H2	1.17e-04	186	114	5	9a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCell	343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LGMN EPS8 ETV5 PTPRJ CLTC	1.17e-04	186	114	5	9673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell	Children_(3_yrs)-Immune-B_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCOA3 ARHGAP15 ANGPTL1 ENAM PLCG2	1.17e-04	186	114	5	aa576748921a318798b911a611f05319b95e8d5e
ToppCell	Immune-B_cell\|World / Lineage, Cell type, age group and donor	NCOA3 ARHGAP15 ANGPTL1 ENAM PLCG2	1.20e-04	187	114	5	795690c6306c366e733279491138d0cd9b469b21
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TEAD2 ABCG1 PTPRJ P3H2 CCDC33	1.20e-04	187	114	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THEMIS2 LGMN BCAT1 ABCG1 MYO1F	1.23e-04	188	114	5	3be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 CACNA1C TRPC4 P3H2 PLCB4	1.23e-04	188	114	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CDR2 LRRK2 CELSR1 P3H2	1.23e-04	188	114	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP15 SLFN5 GZMA MYO1F PLCG2	1.23e-04	188	114	5	1082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	SEMA3F TEAD2 LDB2 SLCO2A1 PLCB4	1.26e-04	189	114	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	SEMA3F LDB2 SLCO2A1 PLCB4 PLCG2	1.26e-04	189	114	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	(2)_5-FU-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	LGMN STAB2 LDB2 SLCO2A1 CLTC	1.29e-04	190	114	5	6b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGMN ARHGAP15 ETV5 BCAT1 MYO1F	1.29e-04	190	114	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SEMA3F TEAD2 SLFN5 LDB2	1.29e-04	190	114	5	cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SEMA3F TEAD2 SLFN5 LDB2	1.29e-04	190	114	5	5bf3d0beee69879c95265d07fba023626a7cc808
ToppCell	(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	LGMN STAB2 SLFN5 LDB2 SLCO2A1	1.29e-04	190	114	5	ff083168d609957d00888f31b3488d6d56c902b4
ToppCell	Endothelial-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SEMA3F CBLN1 LDB2 SLCO2A1 PLCB4	1.32e-04	191	114	5	f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	THEMIS2 ARHGAP15 LRRK2 BCAT1 ABCG1	1.32e-04	191	114	5	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGMN ARHGAP15 ETV5 BCAT1 MYO1F	1.32e-04	191	114	5	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ENPP1 SLFN5 LDB2 CELSR1 GZMA	1.32e-04	191	114	5	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 ACACA LRRK2 ETV5 P3H2	1.32e-04	191	114	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ENPP1 SLFN5 LDB2 CELSR1 GZMA	1.32e-04	191	114	5	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	THEMIS2 LGMN SLFN5 DCLRE1C RABGAP1L	1.32e-04	191	114	5	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	COVID-19-Myeloid-DC1\|COVID-19 / Condition, Lineage and Cell class	PNMA1 ENPP1 LRRK2 CLCN4 P3H2	1.32e-04	191	114	5	9e44357cdeca46d2b26124bb063c8422ef930083
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ENPP1 SLFN5 LDB2 CELSR1 GZMA	1.32e-04	191	114	5	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CRISPLD2 CACNA1C ARHGAP15 TRPC4 LDB2	1.32e-04	191	114	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
Disease	platelet component distribution width	THEMIS2 PRUNE2 CACNA1C ARHGAP15 LRRK2 ETV5 RFX2 C2CD5 P3H2 SLC35B4 USP7 PLCG2 BRWD1 XPO7	8.71e-07	755	110	14	EFO_0007984
Disease	periostin measurement	STAB2 TRPC4	8.22e-05	4	110	2	EFO_0020628
Disease	primary ciliary dyskinesia (is_implicated_in)	DNAH7 BRWD1	2.05e-04	6	110	2	DOID:9562 (is_implicated_in)
Disease	factor VIII measurement, venous thromboembolism	STAB2 PTPRJ PLCG2	2.77e-04	34	110	3	EFO_0004286, EFO_0004630
Disease	response to sulfasalazine, Drug-induced agranulocytosis	ATP6V1H IFT88 OSBPL3	3.57e-04	37	110	3	EFO_0008324, HP_0012235
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C ARHGAP15 PTPRJ RABGAP1L	4.85e-04	97	110	4	EFO_0007878, EFO_0009458
Disease	venous thromboembolism, von Willebrand factor measurement	STAB2 PTPRJ PLCG2	5.21e-04	42	110	3	EFO_0004286, EFO_0004629
Disease	vitamin B6 measurement	CACNA1C OSBPL3	6.08e-04	10	110	2	EFO_0004621
Disease	nicotine dependence (implicated_via_orthology)	TRPC4 PLCB4	8.87e-04	12	110	2	DOID:0050742 (implicated_via_orthology)
Disease	Oligospermia	TPCN1 BRWD1	8.87e-04	12	110	2	C0028960
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	EPS8 ADCY1	1.05e-03	13	110	2	C1846647
Disease	unipolar depression, mood disorder	ARHGAP15 NCOA5 PTPRJ RABGAP1L	1.62e-03	134	110	4	EFO_0003761, EFO_0004247
Disease	Malignant neoplasm of breast	THEMIS2 NCOA3 CYP19A1 TRPC4 YY2 ELP1 SIX4 RFX2 BRCA1 P3H2 MROH7	2.26e-03	1074	110	11	C0006142
Disease	Liver Cirrhosis, Experimental	PRUNE2 LGMN RMND5B IKBKG ACOX2 ABCG1 RABGAP1L GZMA MYO1F	2.47e-03	774	110	9	C0023893
Disease	Anophthalmia-microphthalmia syndrome	SOX2 IKBKG	2.76e-03	21	110	2	cv:C5680330
Disease	Ovarian Serous Adenocarcinoma	LRRK2 MAST1	3.31e-03	23	110	2	C1335177

Protein segments in the cluster

Peptide	Gene	Start	Entry
PQRQSALNTEKMYRM	TDRD1	1126	Q9BXT4
RQMHPDIESERYMQS	ACOX2	16	Q99424
FQPNLNMDRMYRSAV	BCAT1	111	P54687
MAAYQQEEQMQLPRA	CATSPER2	1	Q96P56
KYNNPAMLHNIDQEM	COPS3	366	Q9UNS2
VPEMSHDTEMNNYRR	CCDC33	626	Q8N5R6
YIMQDDMLLPHLTVQ	ABCG1	161	P45844
FEQMYEEMLQTQHRN	ABCB5	896	Q2M3G0
DRNHYNFNPVIGMNM	GZMA	181	P12544
IDSSINPRHMEMYAD	ACACA	2096	Q13085
QFHMKSPQMERYQLS	ERVV-2	491	B6SEH9
MNSRVTQLYMQLLHE	ANGPTL1	126	O95841
DVLRHMAQMANQDPE	CLCN4	741	P51793
NAQIMYQIVEGDMRH	CELSR1	1031	Q9NYQ6
LMVPNEHIMNVIAIY	BPTF	236	Q12830
RQRVQDLMAQMQGPY	CAPRIN1	356	Q14444
RLLTNMTVTNEYQHM	ARMCX3	226	Q9UH62
IMQGIYMQLSHIQEP	MROH7	746	Q68CQ1
VGNPEHMEMQQNLDY	P3H1	171	Q32P28
YNPSMVREFVMQEAQ	PPP4R3A	391	Q6IN85
MHRPLMVQTEDQYVF	PTPRJ	1276	Q12913
TLNPMVYSFQNREMQ	OR13G1	281	Q8NGZ3
TRLHMSNMSDQGPYN	LRRTM2	471	O43300
PHRMYNEIIHLMQQE	LIPM	396	Q5VYY2
PMHQQQSRSVMTEEY	FUBP1	91	Q96AE4
EPMQELMSRHKTYNL	LDB2	211	O43679
DQMEYMLQNHVFPLF	IPO7	451	O95373
QEHRNMPQADAMVLV	NCOA5	276	Q9HCD5
MPQADAMVLVARNYE	NCOA5	281	Q9HCD5
LRGQVQPQASNMEYM	CRISPLD2	66	Q9H0B8
MYQFECMIQEHLPEL	EVI5	291	O60447
MDSVLHTLQMYPDDQ	LRRK2	586	Q5S007
QYQAPDMDTLQIHVM	IKBKG	401	Q9Y6K9
LNPLYRESVLQMMQA	LONP1	306	P36776
RQAAFQMQMHESALP	ELP1	176	O95163
QHQFMSGYSQDILMP	ENPP1	676	P22413
MMPENQYPSEQRFQR	ETV5	206	P41161
YDAVDMQDMNNPLSH	PLCG2	306	P16885
HMEMQQNIENYRATA	P3H2	181	Q8IVL5
SAQMQRMEVENPNYA	ITPRID2	221	P28290
RSPSSYDNEIVMMNH	MAST1	166	Q9Y2H9
MRESQLQQEDPMDRY	RABGAP1L	796	Q5R372
NAVEEAMGMYQELHR	IFT172	706	Q9UG01
NQMPVRHSRNLQLME	BRCA1	656	P38398
RENPQDFIDMYLLHM	CYP2U1	311	Q7Z449
PAQDSDYVLRNMMVT	EFCAB5	1191	A4FU69
AQHFLMSNPRNMDLY	ADCY1	846	Q08828
TNMYNTERANPMLNL	CDHR2	1211	Q9BYE9
YRMALDQVPSVNKQM	IFT88	256	Q13099
AINSYEHIMSMAPNL	IFT88	291	Q13099
NHEPSEMSNRTMIIY	CBLN1	71	P23435
QVHVNKLDMFRNMPE	DCLRE1C	226	Q96SD1
MVNENTRMYIPEENH	CACNA1C	1	Q13936
VTMAMEHYQQPQILD	CACNA1G	1626	O43497
MVLEMLNPIHYNITS	CYP19A1	1	P11511
EMRQMLQSEHPFVNG	CDR2	256	Q01850
YIRDHLNAMNPTMLA	DNAH7	266	Q8WXX0
MMQLYIRENGSPEEH	FAM172A	256	Q8WUF8
RMTPAELANMEHLYE	BRWD1	926	Q9NSI6
LMCPMHDDYDLRQEQ	DNAJC13	481	O75165
YGMQITRMNSPEREH	ENAM	831	Q9NRM1
QYHEQEETPEMMAAR	EPS8	251	Q12929
ANFPQYVMDVLMDQH	DDX17	176	Q92841
LLNMYHQALSTRMQD	EXOC3	311	O60645
EETLQAAMPQVSYRM	PNMA1	36	Q8ND90
MDIRPNHTIYINNMN	SNRPB2	1	P08579
NLLPFMEYEVHTQLM	C2CD5	536	Q86YS7
LDVNTRNPNYEIMHM	KIF2B	176	Q8N4N8
MYRQNEIAMFPHEVN	OSBPL3	146	Q9H4L5
MQRTYFPMNIENESI	MINAR1	211	Q9UPX6
PRNHSLMDDYQEMNE	FER1L6	371	Q2WGJ9
AAQMQPMHRYDVSAL	SOX2	191	P48431
VQPSQADARMLMYQH	TRMT1	206	Q9NXH9
QYILTMVDDMLQENH	ATP6V1H	91	Q9UI12
NYALNLNIAMPLHMI	SLC35B4	81	Q969S0
RMVMNNGLNPVYNEE	PLCB4	741	Q15147
DPSMMQLYNETNRQL	PRUNE2	1081	Q8WUY3
VINFMRSHPLMYQAV	SEMA3F	431	Q13275
EQMRDNSPVHLQYSM	SLITRK6	646	Q9H5Y7
MEYHSPDDNRMNRNR	TAB3	56	Q8N5C8
QFNMHVDSRRPVMDQ	TDRD9	716	Q8NDG6
SPLNRLQEDTQYMAM	RFX2	276	P48378
INASPEMRQRYETMQ	NCOA3	211	Q9Y6Q9
HMVYQNQIAELMLSE	ARHGAP15	451	Q53QZ3
NLSLSSHMEPVYMQQ	SIX4	321	Q9UIU6
ASAMDIQVPYNMERV	THNSL2	311	Q86YJ6
MAMLTHLNEPAVLYN	MYH3	91	P11055
RQLPERYMMNSVLEN	TEAD2	391	Q15562
SDVNFMMDYTHRNPA	SLC38A4	281	Q969I6
MMDYTHRNPAGLDEN	SLC38A4	286	Q969I6
LHTDNYDSTNMPLMQ	SGCE	401	O43556
VLEEMLNVHDHYQNM	SNAPC1	176	Q16533
YDNAIITMMNHPTDA	CLTC	1371	Q00610
ISHNPLYMMVLRVVN	SLCO2A1	531	Q92959
MENRNLHSPEYLEMA	UBE3A	291	Q05086
VRNSNPDEQMMTYVI	TCEANC	321	Q8N8B7
PLSREITMSQAYQNM	NAA35	571	Q5VZE5
QMAIVEHLYQQGMLS	RMND5B	121	Q96G75
LDGAVMMYNLSVHQQ	RNF123	751	Q5XPI4
PQYEIQAIMHMRRTI	THEMIS2	206	Q5TEJ8
YGDHDQEMLMLQTQE	YY2	71	O15391
LHIIAGQMNIEYMNN	STAB2	436	Q8WWQ8
MYETMEQLRNLPQQC	TBC1D10B	576	Q4KMP7
RYPSLMENNNMRIQD	PPP1R36	391	Q96LQ0
HMHNIVEYMLQRTQD	TNPO1	261	Q92973
FEYMQEHTLERNPMN	ZNF844	601	Q08AG5
LETLSQMERYQQHSM	TPCN1	741	Q9ULQ1
RENLIMRPDQMYGNV	WFIKKN1	226	Q96NZ8
SQAIIQMIVEDMHPY	ZBED6	411	P86452
DRFLHIMQQHPEMIQ	XPO7	966	Q9UIA9
LMQDMEHPQRQNVAV	ZYX	366	Q15942
LPSYNMDRAAVQTNM	UBAC1	131	Q9BSL1
AVNMNLHYLENGTVM	POLR1B	221	Q9H9Y6
VLHLQLMRFMYDPQT	USP7	401	Q93009
ESYNFMTPQHMEALL	SLFN5	516	Q08AF3
LIAMMNNSYQLIADH	TRPC4	616	Q9UBN4
SGSMMNHLPDNINVY	LGMN	191	Q99538
LLRAVNMEPDQYQMG	MYO1F	656	O00160