Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A

3.42e-0814504GO:0031402
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A SCN3A SCN8A

4.99e-0726504GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A

4.99e-0726504GO:0031420
GeneOntologyMolecularFunctiontransporter activity

SLC38A1 SIDT2 ABCA3 ANO6 SCN1A SCN2A SCN3A SCN8A SIDT1 APOB ITGAV SLC38A6 RYR1 ABCB1

2.12e-0612895014GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC38A1 SIDT2 ABCA3 ANO6 SCN1A SCN2A SCN3A SCN8A SIDT1 ITGAV SLC38A6 RYR1 ABCB1

4.58e-0611805013GO:0022857
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN2A SCN3A SCN8A

8.62e-0652504GO:0005272
GeneOntologyMolecularFunctionRNA transmembrane transporter activity

SIDT2 SIDT1

1.84e-053502GO:0051033
GeneOntologyMolecularFunctionnucleic acid transmembrane transporter activity

SIDT2 SIDT1

1.84e-053502GO:0051032
GeneOntologyMolecularFunctionmonoatomic cation channel activity

ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

2.20e-05343507GO:0005261
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1N1 FZD6 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

5.63e-058845010GO:0004930
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A1 SCN1A SCN2A SCN3A SCN8A

6.74e-05171505GO:0015081
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

ANO6 SCN1A SCN2A ITGAV RYR1

9.05e-05182505GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

ANO6 SCN1A SCN2A ITGAV RYR1

9.53e-05184505GO:0022832
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

1.38e-04459507GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC38A1 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

1.49e-04465507GO:0046873
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A1 SLC38A6

2.19e-049502GO:0015186
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC38A1 ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

2.24e-04664508GO:0008324
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA3 ANO6 ABCB1

2.83e-0451503GO:0140303
GeneOntologyMolecularFunctionchannel activity

ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

3.13e-04525507GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

3.17e-04526507GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC38A1 ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

5.43e-04758508GO:0015318
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ABCA3 ABCB1

5.49e-0414502GO:0140333
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCA3 ABCB1

6.32e-0415502GO:0008559
GeneOntologyMolecularFunctionicosanoid receptor activity

CYSLTR1 PTGER2

7.21e-0416502GO:0004953
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC38A1 ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

7.30e-04793508GO:0015075
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

8.16e-0417502GO:0099508
GeneOntologyMolecularFunctionflippase activity

ABCA3 ABCB1

8.16e-0417502GO:0140327
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCA3 ANO6 ABCB1

8.45e-0474503GO:0005548
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC38A1 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1

9.00e-04627507GO:0022890
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA3 ABCB1

1.13e-0320502GO:0008525
GeneOntologyMolecularFunctiongated channel activity

ANO6 SCN1A SCN2A ITGAV RYR1

1.45e-03334505GO:0022836
GeneOntologyMolecularFunctionlipid transporter activity

ABCA3 ANO6 APOB ABCB1

1.46e-03196504GO:0005319
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR1N1 FZD6 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

1.67e-0313535010GO:0004888
GeneOntologyMolecularFunctiontransforming growth factor beta binding

CD109 ITGAV

1.92e-0326502GO:0050431
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA3 ABCB1

2.23e-0328502GO:0140326
GeneOntologyMolecularFunctionmacromolecule transmembrane transporter activity

SIDT2 SIDT1

3.28e-0334502GO:0022884
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCA3 ABCB1

3.28e-0334502GO:0042910
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

RELN APOB

4.29e-0339502GO:0070325
GeneOntologyMolecularFunctionolfactory receptor activity

OR1N1 OR5AU1 OR1L6 OR2T4 OR1L4

4.37e-03431505GO:0004984
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC38A1 SLC38A6

4.73e-0341502GO:0015175
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

ITGAV RYR1

5.93e-0346502GO:0005245
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA3 ABCB1

6.70e-0349502GO:0140359
GeneOntologyMolecularFunctionlipid transfer activity

ABCA3 APOB

8.98e-0357502GO:0120013
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SIDT2 SIDT1

9.60e-0359502GO:0015932
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN3A SCN8A

1.70e-0636504GO:0086010
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC38A1 ANO6 SCN1A SCN2A SCN3A SCN8A

1.07e-05208506GO:0035725
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN3A SCN8A

1.54e-0562504GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN3A SCN8A

1.64e-0563504GO:0019228
GeneOntologyBiologicalProcesssodium ion transport

SLC38A1 ANO6 SCN1A SCN2A SCN3A SCN8A

5.17e-05275506GO:0006814
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN3A SCN8A

5.86e-0587504GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN3A SCN8A

7.61e-0593504GO:0086003
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN2A SCN3A SCN8A

1.56e-04112504GO:0019226
GeneOntologyBiologicalProcessstriated muscle contraction

SCN1A SCN2A SCN3A SCN8A RYR1

1.77e-04217505GO:0006941
GeneOntologyBiologicalProcessmembrane depolarization

SCN1A SCN2A SCN3A SCN8A

2.11e-04121504GO:0051899
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN2A SCN3A SCN8A

2.54e-04127504GO:0070252
GeneOntologyBiologicalProcessglutamine transport

SLC38A1 SLC38A6

2.56e-0410502GO:0006868
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC38A1 RELN ANO6 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1 ABCB1

2.91e-0411155010GO:0034220
GeneOntologyBiologicalProcesscirculatory system process

SLC38A1 CYSLTR1 SCN1A SCN2A SCN3A SCN8A PTGER2 ABCB1

3.51e-04733508GO:0003013
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC38A1 RELN ANO6 CYSLTR1 SCN1A SCN2A SCN3A SCN8A ITGAV RYR1 ABCB1

3.68e-0413745011GO:0006811
GeneOntologyBiologicalProcesslipid translocation

ABCA3 ANO6 ABCB1

4.16e-0460503GO:0034204
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

SLC38A1 RELN ANO6 ABCB1 AZIN1

5.10e-04273505GO:0034764
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN2A SCN3A SCN8A

5.14e-04153504GO:0030048
GeneOntologyBiologicalProcessfemale meiosis I

MEIOC TRIM75

5.14e-0414502GO:0007144
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCA3 ANO6 ABCB1

5.27e-0465503GO:0097035
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A SCN8A

6.74e-0817504GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A SCN8A

6.58e-0729504GO:0034706
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

1.43e-0520503GO:0033268
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

4.50e-0529503GO:0043194
GeneOntologyCellularComponentexternal side of apical plasma membrane

SLC38A1 ABCB1

8.36e-056502GO:0098591
GeneOntologyCellularComponentcation channel complex

SCN1A SCN2A SCN3A SCN8A RYR1

2.41e-04235505GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

ANO6 SCN1A SCN2A SCN3A SCN8A RYR1

2.73e-04378506GO:0034702
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A RYR1

8.96e-0479503GO:0030315
GeneOntologyCellularComponentmain axon

SCN1A SCN2A SCN8A

1.27e-0389503GO:0044304
GeneOntologyCellularComponenttransmembrane transporter complex

ANO6 SCN1A SCN2A SCN3A SCN8A RYR1

1.49e-03523506GO:1902495
GeneOntologyCellularComponenttransporter complex

ANO6 SCN1A SCN2A SCN3A SCN8A RYR1

1.92e-03550506GO:1990351
HumanPhenoFocal automatism seizure

RELN SCN1A SCN2A SCN8A

1.03e-0712214HP:0032898
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

3.52e-0627214HP:0011171
HumanPhenoClonic seizure

RELN SCN1A SCN2A SCN3A SCN8A

1.50e-0581215HP:0020221
HumanPhenoFocal non-motor seizure

RELN SCN1A SCN2A SCN8A

1.77e-0540214HP:0032679
HumanPhenoImpulsivity

UBA5 RELN SCN1A SCN2A SCN3A SCN8A

2.14e-05149216HP:0100710
HumanPhenoFocal clonic seizure

RELN SCN1A SCN2A SCN8A

2.16e-0542214HP:0002266
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A

3.27e-0516213HP:0011172
HumanPhenoBilateral tonic-clonic seizure with focal onset

RELN SCN1A SCN2A SCN8A

5.08e-0552214HP:0007334
HumanPhenoFocal sensory seizure

RELN SCN1A SCN8A

8.84e-0522213HP:0011157
HumanPhenoEpileptic encephalopathy

UBA5 SCN1A SCN2A SCN3A SCN8A

9.65e-05119215HP:0200134
HumanPhenoFocal impaired awareness seizure

RELN SCN1A SCN2A SCN3A SCN8A

1.27e-04126215HP:0002384
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A

1.31e-0425213HP:0006813
HumanPhenoEpileptic aura

RELN SCN1A SCN8A

1.31e-0425213HP:0033348
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

1.61e-045212HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

1.61e-045212HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

1.61e-045212HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

1.61e-045212HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

1.61e-045212HP:0032906
HumanPhenoRigidity

UBA5 SCN1A SCN2A SCN3A SCN8A RYR1

1.64e-04214216HP:0002063
HumanPhenoFocal aware seizure

RELN SCN1A SCN2A

1.85e-0428213HP:0002349
HumanPhenoMortality/Aging

MYF6 TRMT10C ABCA3 SCN1A DHCR7 GNPTAB SCN8A APOB RYR1

1.99e-04563219HP:0040006
HumanPhenoAge of death

MYF6 TRMT10C ABCA3 SCN1A DHCR7 GNPTAB SCN8A APOB RYR1

1.99e-04563219HP:0011420
HumanPhenoNormal interictal EEG

SCN2A SCN8A

2.40e-046212HP:0002372
HumanPhenoCavernous hemangioma

MYF6 GNPTAB RYR1

2.52e-0431213HP:0001048
HumanPhenoDecreased fetal movement

UBA5 MYF6 DHCR7 SCN3A SCN8A RYR1

2.67e-04234216HP:0001558
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A

3.33e-0434213HP:0011169
HumanPhenoEyelid myoclonia seizure

SCN2A SCN8A

3.36e-047212HP:0032678
HumanPhenoPrenatal movement abnormality

UBA5 MYF6 DHCR7 SCN3A SCN8A RYR1

3.51e-04246216HP:0001557
HumanPhenoEEG with abnormally slow frequencies

UBA5 SCN1A SCN3A SCN8A

3.98e-0488214HP:0011203
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A

4.47e-048212HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A

4.47e-048212HP:0200048
HumanPhenoMacrocephaly at birth

MYF6 RYR1

5.73e-049212HP:0004488
HumanPhenoAggressive behavior

UBA5 RELN KIF15 SCN1A DHCR7 SCN2A SCN3A SCN8A

6.47e-04516218HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

UBA5 RELN KIF15 SCN1A DHCR7 SCN2A SCN3A SCN8A

6.47e-04516218HP:0006919
HumanPhenoSudden unexpected death in epilepsy

SCN1A SCN8A

7.14e-0410212HP:0033258
HumanPhenoPsychic epileptic aura

RELN SCN8A

7.14e-0410212HP:0033346
HumanPhenoExperiential epileptic aura

RELN SCN8A

7.14e-0410212HP:0012002
HumanPhenoHypsarrhythmia

UBA5 SCN1A SCN2A SCN3A SCN8A

7.58e-04185215HP:0002521
HumanPhenoNeonatal seizure

SCN2A SCN8A

8.71e-0411212HP:0032807
HumanPhenoFocal autonomic seizure

RELN SCN8A

8.71e-0411212HP:0011154
HumanPhenoLimited neck range of motion

SCN1A SCN2A

8.71e-0411212HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A

1.04e-0312212HP:0012847
HumanPhenoAbnormal fetal physiology

UBA5 MYF6 DHCR7 SCN3A SCN8A RYR1

1.16e-03308216HP:0034059
HumanPhenoCyanosis

ABCA3 SCN1A SCN2A SCN8A

1.17e-03117214HP:0000961
HumanPhenoEEG with multifocal slow activity

UBA5 SCN3A SCN8A

1.17e-0352213HP:0010844
HumanPhenoEEG with focal epileptiform discharges

RELN SCN1A SCN2A SCN8A

1.21e-03118214HP:0011185
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A

1.23e-0313212HP:0007058
HumanPhenoStatus epilepticus

UBA5 SCN1A SCN2A SCN3A SCN8A

1.26e-03207215HP:0002133
MousePhenoabnormal respiratory function

MYF6 ABCA3 SCN1A DHCR7 SCN2A SCN8A PTGER2 RYR1

7.67e-06399378MP:0002327
MousePhenoabnormal breathing pattern

MYF6 ABCA3 SCN1A DHCR7 SCN2A SCN8A RYR1

1.24e-05303377MP:0001951
MousePhenoabnormal respiratory system physiology

MYF6 ABCA3 CYSLTR1 DTX1 SCN1A DHCR7 SCN2A SCN8A PTGER2 RYR1

7.98e-058973710MP:0002133
MousePhenoabnormal extraocular muscle morphology

MYF6 RYR1

1.02e-046372MP:0005247
MousePhenoabnormal respiration

MYF6 ABCA3 SCN1A DHCR7 SCN2A SCN8A PTGER2 RYR1

1.37e-04598378MP:0001943
MousePhenorespiratory distress

MYF6 ABCA3 SCN2A SCN8A RYR1

1.88e-04204375MP:0001954
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A

6.25e-106494PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A

6.25e-106494IPR024583
DomainNa_channel_asu

SCN1A SCN2A SCN3A SCN8A

8.68e-0910494IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN8A

8.68e-0910494IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN8A

8.68e-0910494PF06512
DomainSID1_TM_fam

SIDT2 SIDT1

6.74e-062492IPR025958
DomainSID-1_RNA_chan

SIDT2 SIDT1

6.74e-062492PF13965
DomainIon_trans_dom

SCN1A SCN2A SCN3A SCN8A RYR1

1.19e-05114495IPR005821
DomainIon_trans

SCN1A SCN2A SCN3A SCN8A RYR1

1.19e-05114495PF00520
DomainChannel_four-helix_dom

SCN1A SCN2A SCN3A SCN8A

1.49e-0557494IPR027359
Domain-

SCN1A SCN2A SCN3A SCN8A

1.49e-05574941.20.120.350
DomainGPCR_Rhodpsn_7TM

OR1N1 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

5.29e-05670499IPR017452
Domain7tm_1

OR1N1 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

5.74e-05677499PF00001
DomainIQ

SCN1A SCN2A SCN3A SCN8A

6.00e-0581494SM00015
DomainG_PROTEIN_RECEP_F1_1

OR1N1 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

6.28e-05685499PS00237
DomainG_PROTEIN_RECEP_F1_2

OR1N1 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

6.72e-05691499PS50262
DomainGPCR_Rhodpsn

OR1N1 GPR65 OR5AU1 MLNR CYSLTR1 OR1L6 OR2T4 PTGER2 OR1L4

6.79e-05692499IPR000276
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN3A SCN8A

9.05e-0590494IPR000048
DomainEF-hand-dom_pair

SCN1A GNPTAB SCN3A SCN8A EFCAB3 RYR1

1.00e-04287496IPR011992
DomainIQ

SCN1A SCN2A SCN3A SCN8A

1.03e-0493494PS50096
DomainIQ

SCN1A SCN3A SCN8A

8.56e-0471493PF00612
DomainAa_trans

SLC38A1 SLC38A6

8.94e-0417492PF01490
DomainAA_transpt_TM

SLC38A1 SLC38A6

8.94e-0417492IPR013057
DomainEF-hand_8

EFCAB3 RYR1

3.59e-0334492PF13833
DomainOlfact_rcpt

OR1N1 OR5AU1 OR1L6 OR2T4 OR1L4

3.59e-03393495IPR000725
DomainABC_transporter_CS

ABCA3 ABCB1

5.43e-0342492IPR017871
DomainABC_TRANSPORTER_2

ABCA3 ABCB1

7.04e-0348492PS50893
DomainABC_tran

ABCA3 ABCB1

7.04e-0348492PF00005
DomainABC_TRANSPORTER_1

ABCA3 ABCB1

7.33e-0349492PS00211
DomainABC_transporter-like

ABCA3 ABCB1

7.62e-0350492IPR003439
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

9.76e-0728394M45519
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A SCN8A

1.49e-0631394M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A SCN8A

1.70e-0632394M27455
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN3A SCN8A ITGAV

1.95e-05121395M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN2A SCN3A SCN8A RYR1

2.76e-05130395M27454
PathwayREACTOME_MUSCLE_CONTRACTION

SCN1A SCN2A SCN3A SCN8A RYR1

2.28e-04203395M5485
PathwayREACTOME_SENSORY_PERCEPTION

OR1N1 OR5AU1 SCN2A SCN3A OR1L6 APOB OR2T4 OR1L4

2.92e-04636398M41834
PathwayWP_RETT_SYNDROME

SCN1A SCN2A SCN8A

3.11e-0448393M39759
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

CYSLTR1 PTGER2

6.65e-0414392MM15012
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

CYSLTR1 PTGER2

7.65e-0415392M10620
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

3.78e-12450417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

3.78e-12450435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

3.78e-12450429578003
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A

5.66e-11650423652591
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A SCN8A

4.74e-10950416382098
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN8A

4.74e-10950415746173
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN8A

1.85e-091250430175250
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN8A

2.68e-091350415123669
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

2.80e-09350323859570
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

2.80e-09350312610651
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

2.80e-09350318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

2.80e-09350317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

2.80e-09350332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

2.80e-09350328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

2.80e-09350317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

2.80e-09350314973256
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

1.12e-08450335801810
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

1.12e-08450321156207
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

1.12e-0845038974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

2.79e-0855031679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A

2.79e-0855038812438
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

2.79e-08550324337656
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN8A

2.79e-08550317724025
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

9.75e-08750325818041
Pubmed

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.

SCN1A SCN2A ABCB1

3.33e-071050320602612
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

6.09e-07125038169823
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

1.26e-06155039726281
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

2.03e-06250220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.03e-06250237901435
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.03e-06250226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

2.03e-06250210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

2.03e-06250219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

2.03e-06250235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

2.03e-06250211245985
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

2.03e-06250215760941
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

2.03e-0625021317301
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

2.03e-06250223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

2.03e-06250227153334
Pubmed

Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia.

GPR65 IL1B

2.03e-06250224447140
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

2.03e-06250224990319
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

2.03e-06250231439038
Pubmed

[Pharmacogenetic criteria of drug-resistant epilepsy].

SCN1A ABCB1

2.03e-06250223786015
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

2.03e-06250231943325
Pubmed

A novel family of mammalian transmembrane proteins involved in cholesterol transport.

SIDT2 SIDT1

2.03e-06250228785058
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

2.03e-06250215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

2.03e-06250227690330
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

2.03e-06250218601978
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

2.03e-06250223965409
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

2.03e-06250219465131
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

2.03e-06250230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

2.03e-06250223735284
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

2.03e-06250229649454
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

2.03e-06250233096315
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

2.03e-06250217805013
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

2.03e-06250226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

2.03e-06250233411788
Pubmed

Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.

SIDT2 SIDT1

2.03e-06250226067272
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

2.03e-06250221377452
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

2.03e-06250237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

2.03e-06250217881658
Pubmed

Report and abstracts of the Fourth International Workshop on Human Chromosome 2 Mapping 1996.

SCN1A SCN2A SCN3A IL1B

3.42e-06715048751373
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

SLC38A1 ABCA3 ABCB1

3.65e-062150323137377
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A

6.07e-06350219284629
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

6.07e-06350232185219
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

6.07e-06350232005694
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A

6.07e-06350233895391
Pubmed

Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.

SCN2A SCN8A

6.07e-06350216033895
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

6.07e-06350227816501
Pubmed

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

IL1B ITGAV

6.07e-06350218276918
Pubmed

Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head.

APOB ABCB1

6.07e-06350218696186
Pubmed

Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6.

SCN2A SCN8A

6.07e-06350238514708
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

6.07e-06350226182346
Pubmed

De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.

SCN1A SCN8A

6.07e-06350231054517
Pubmed

Localization of the reeler gene relative to flanking loci on mouse chromosome 5.

RELN ABCB1

6.07e-0635021686837
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

6.07e-06350228784306
Pubmed

[Association of SCN2A, ABCB1 and CYP2C19*3 with genetic susceptibility to major depressive disorder].

SCN2A ABCB1

6.07e-06350235381649
Pubmed

Effects of CYP2C19, MDR1, and interleukin 1-B gene variants on the eradication rate of Helicobacter pylori infection by triple therapy with pantoprazole, amoxicillin, and metronidazole.

IL1B ABCB1

6.07e-06350220376628
Pubmed

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

SCN2A SCN8A

6.07e-06350229991598
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

6.07e-06350224704313
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

6.07e-06350219270815
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

6.07e-06350216052353
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

6.07e-06350225155934
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

6.07e-06350228117367
Pubmed

ABCB1 c.3435C > T and EPHX1 c.416A > G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients.

SCN1A ABCB1

6.07e-06350234411648
Pubmed

[Genetic analysis for prevention of steroid-induced osteonecrosis of the femoral head].

APOB ABCB1

6.07e-06350217548929
Pubmed

Mouse multidrug resistance 1a/3 gene is the earliest known endothelial cell differentiation marker during blood-brain barrier development.

RELN ABCB1

6.07e-0635027734734
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SCN1A SCN2A

1.21e-05450226637798
Pubmed

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

IL1B PTGER2

1.21e-05450219273625
Pubmed

Direct detection and isolation of restriction landmark genomic scanning (RLGS) spot DNA markers tightly linked to a specific trait by using the RLGS spot-bombing method.

RELN ABCB1

1.21e-0545027777557
Pubmed

mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2.

ABCA3 ABCB1

1.21e-05450224145140
Pubmed

Models for discovery of targeted therapy in genetic epileptic encephalopathies.

SCN1A SCN8A

1.21e-05450228742937
Pubmed

Interleukin-1β Promotes Epithelial-Derived Alveolar Elastogenesis via αvβ6 Integrin-Dependent TGF-β Activation.

IL1B ITGAV

1.21e-05450226279426
Pubmed

The reeler gene: a clue to brain development and evolution.

RELN ABCB1

1.21e-0545021627461
Pubmed

Interaction of CCN1 with αvβ3 integrin induces P-glycoprotein and confers vinblastine resistance in renal cell carcinoma cells.

ITGAV ABCB1

1.21e-05450223744557
Pubmed

Estimation of genetic distances between "reeler" and nearby loci on mouse chromosome 5.

RELN ABCB1

1.21e-0545021783386
Pubmed

Comparison of oxcarbazepine efficacy and MHD concentrations relative to age and BMI: Associations among ABCB1, ABCC2, UGT2B7, and SCN2A polymorphisms.

SCN2A ABCB1

1.21e-05450230896644
Pubmed

Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.

APOB ABCB1

1.21e-05450232243098
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN8A

2.02e-05550222875929
Pubmed

Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene.

RELN ABCB1

2.02e-0555028081873
Pubmed

Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression.

SCN2A SCN8A

2.02e-05550224077057
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

6.18e-078463int:SCN4B
InteractionTMPRSS12 interactions

FZD6 SIDT2 ABCA3

1.91e-0523463int:TMPRSS12
InteractionADGRG5 interactions

FZD6 SIDT2 ABCA3 ANO6

5.98e-0593464int:ADGRG5
InteractionTMPRSS4 interactions

SLC38A1 TRMT10C ANO6 DHCR7 APOB ITGAV

7.56e-05314466int:TMPRSS4
Cytoband9q33.2

OR1N1 OR1L6 OR1L4

1.08e-05395039q33.2
Cytoband2q24.3

SCN1A SCN2A

1.38e-04165022q24.3
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A

3.68e-04127503chr2q24
CytobandEnsembl 112 genes in cytogenetic band chr9q33

OR1N1 OR1L6 OR1L4

4.70e-04138503chr9q33
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A SCN8A

2.07e-0993841203
GeneFamilyOlfactory receptors, family 1

OR1N1 OR1L6 OR1L4

8.02e-0540383147
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

SLC38A1 FZD6 RELN ABCA3 DTX1 SCN3A ITGAV

7.02e-06402477M45754
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN

FZD6 DHCR7 GNPTAB SCN3A PTGER2

2.91e-05200475M8027
CoexpressionFEKIR_HEPARG_SPHERE_VS_HEPARG_UP

KIAA0930 GNPTAB IL1B ITGAV

3.52e-05103474M48358
ToppCelldroplet-Bladder-nan-3m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 CYSLTR1 IL1B RYR1

1.09e-061635052f32a9ab0230fdca98ffa7fd59397301d50e4f30
ToppCelldroplet-Bladder-nan-3m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 CYSLTR1 IL1B RYR1

1.09e-061635056c2967dee563295febe2adabf503d095cb911ccf
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.16e-06165505347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.16e-06165505507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.16e-0616550539a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.16e-061655051890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.30e-06169505f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.34e-0617050535e3945d8a540a3e2cec1b559316265aaad023d1
ToppCellPND01-Endothelial-Endothelial_lymphatic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.34e-061705050ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A CD109

1.34e-061705050b5ddc7d452db0a389927a367914f7d257703f7e
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

SLC38A1 CYSLTR1 DTX1 SCN3A SIDT1

1.63e-06177505f54691e5558091c1734ab15153a10bff15ed171e
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GPR65 CYSLTR1 RYR1 ABCB1

1.98e-0618450533db879e629821fb75684e60f8f0749cf9623bdd
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR65 KIF15 CYSLTR1 ABCB1

1.96e-05142504be63c48794a227ea55978524c0f5935342fc455e
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD9L IL1B ITGAV RYR1

2.56e-0515250482a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellfacs-MAT-Fat-24m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0930 GPR65 CYSLTR1 IL1B

2.76e-05155504d0c1608f8f6b6f4174e51d610501c707cba5e015
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.20e-05161504133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.20e-051615049466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.20e-05161504cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.28e-0516250496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.44e-051645044cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.44e-051645047a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.44e-051645045e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A SCN3A

3.44e-05164504f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN DTX1 SCN1A CD109

3.52e-0516550450a8513d8d2630861499393a7f102b35366bad37
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FZD6 RELN DTX1 SCN3A

3.61e-051665045ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBGCP5 NDRG2 XKRX SLC38A6

3.61e-05166504aa2df07eff323ded751ced8938af08223d7f2029
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 IL1B RYR1

3.61e-051665048e5a262dc4f04c5fc75b9a7a907832a0d7877df0
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

FZD6 RELN DTX1 SCN3A

3.61e-051665046bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 IL1B RYR1

3.61e-05166504e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBGCP5 NDRG2 XKRX SLC38A6

3.61e-05166504695298a94d62b8adab083900003ec636fbaae5d9
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD6 RELN DTX1 SCN3A

3.69e-05167504b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD6 RELN DTX1 SCN3A

3.69e-05167504fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD6 RELN DTX1 SCN3A

3.69e-05167504f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellfacs-MAT-Fat-18m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0930 CYSLTR1 IL1B RYR1

3.69e-05167504c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD6 RELN DTX1 SCN3A

3.69e-0516750426cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCelldroplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 IL1B RYR1

3.78e-05168504c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 CYSLTR1 RYR1

3.87e-05169504b46e446067c6425bd5b8ef7719aeecff5e861249
ToppCellfacs-GAT-Fat-18m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0930 CYSLTR1 IL1B RYR1

3.87e-051695047a7416fcbffcf57d19b477d9da091e04e3499524
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 CYSLTR1 RYR1

3.87e-051695045508b03fbf483fce7701d6c82c297ffda3b1ba05
ToppCellfacs-GAT-Fat-18m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0930 CYSLTR1 IL1B RYR1

3.87e-051695040e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCellfacs-GAT-Fat-18m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0930 CYSLTR1 IL1B RYR1

3.87e-051695049bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR65 CYSLTR1 MFSD11 ABCB1

3.96e-05170504f664c7559e383b37845c123e41a3be316d869ba0
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR65 CYSLTR1 MFSD11 ABCB1

3.96e-051705040272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC38A1 GPR65 IL1B RYR1

4.05e-0517150487cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 PTGER2 RYR1 AZIN1

4.05e-05171504e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC38A1 GNPTAB PTGER2 ABCB1

4.05e-05171504adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCelldroplet-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 GPR65 IL1B RYR1

4.14e-05172504f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 CYSLTR1 IL1B RYR1

4.14e-051725046b01448443cf8392ed8248ff452b80c31240b85d
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC38A1 GPR65 IL1B RYR1

4.14e-05172504f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 CYSLTR1 IL1B RYR1

4.14e-051725040c0ae2da3cba6022403434567800f16e61a34a2b
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 CYSLTR1 IL1B RYR1

4.14e-05172504d80c207f3489be2da2f40f47a7835cb73c949c3e
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD6 RELN DTX1 SCN3A

4.24e-051735049dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA3 GPR65 GNPTAB ABCB1

4.43e-051755048fb8c4b9e2d9b7d737f59cd9bd3dc2bca5a8dfc4
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYF6 GPR65 CYSLTR1 PTGER2

4.63e-051775049828504591599619649d41a78daf7c052729c669
ToppCellControl-Lymphoid-ILC_B|Control / Disease state, Lineage and Cell class

SLC38A1 CYSLTR1 SIDT1 ABCB1

4.63e-051775043d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCellLPS_only-Myeloid-Neutrophils|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

4.84e-05179504d0a03e498afcfeb657037889685ecd77bed07e6c
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 RELN DTX1 SCN3A

4.84e-05179504ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell3'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 CYSLTR1 SCN8A IFIT5

4.84e-051795042285e3a9018a60d7f6e974fee46b6f61d39aa76f
ToppCell3'-Adult-Appendix-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 CYSLTR1 SCN8A IFIT5

4.84e-051795040b0f27d7c5cc5ae7618d887dcfa7219df8ff1935
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 RELN DTX1 SCN3A

4.84e-0517950435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell3'-Adult-Appendix-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 CYSLTR1 SCN8A IFIT5

4.84e-0517950463bc819df62b1f8f37bf1f17bdd4fcc161886923
ToppCellLPS_only-Myeloid-Neutrophils-Neutrophils|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

4.84e-05179504d034651a5a355a58f5e15db627869f4feebdfe35
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 SCN3A TUBGCP5 XKRX

4.94e-0518050464f01494a4052186773720e10b4e7c724ff94547
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 RELN SCN2A RYR1

4.94e-051805046ac62bf1251978c8c12e715f7b73144fca619794
ToppCellLPS-IL1RA-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

4.94e-05180504c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCellLPS-IL1RA-Myeloid-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

4.94e-05180504079c199425dd3c220f03c6dca1823946f07580a1
ToppCellFetal_29-31_weeks-Immune-B_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC38A1 CYSLTR1 DTX1 SCN3A

5.05e-0518150457f20341c3e9f9f6ed5b6c181605ad35bae91414
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 CYSLTR1 DTX1 SCN3A

5.05e-0518150451e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD6 RELN DTX1 SCN3A

5.16e-05182504d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

5.16e-05182504666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPR65 EFCAB3 PTGER2 ABCB1

5.16e-051825048ccffcbae28c374fd4161fb0d4cf2c49fae557f6
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ANO6 EDEM1 XKRX RYR1

5.27e-051835043cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 CYSLTR1 DTX1 SCN3A

5.50e-051855048fc357ee041bfd588986730a52ea2021b5f88941
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD9L GPR65 IFIT5 IL1B

5.50e-05185504f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 RELN DTX1 SCN3A

5.50e-051855043be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellLPS-IL1RA-Myeloid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 IL1B PTGER2 AZIN1

5.50e-051855049b5fd87ea9d05e051ff1251578ecfbe5e8652853
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 RELN DTX1 SCN3A

5.50e-05185504c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

SLC38A1 KIF15 SCN3A EDEM1

5.61e-0518650466676d9395172de5707e204826a1c9f73b448cca
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ANO6 EDEM1 XKRX RYR1

5.61e-05186504bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A SCN8A SIDT1

5.61e-051865047278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GPR65 SIDT1 ABCB1

5.73e-05187504b5c8322ee728303425be677aa0c36fa552fd0f59
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 DTX1 SCN3A SIDT1

5.73e-051875049d298f43ae81d72091b31aaa6df41046d4aa31c5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 SCN1A SCN2A SCN8A

5.73e-051875047b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SCN2A SCN3A ABCB1

5.73e-051875042d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SCN2A SCN3A ABCB1

5.73e-05187504e3095455d2f255854f339f6b05fa87852af0700f
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GPR65 SIDT1 ABCB1

5.85e-05188504624426815b789f0f35c327b8c3c0c05ba3aa7d98
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC38A1 GPR65 SIDT1 ABCB1

5.85e-051885041082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SCN2A SCN3A ABCB1

5.97e-051895043a295c215b5c18e7c673f92b7af5be523421682c
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

SLC38A1 RELN DTX1 SCN3A

5.97e-05189504c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC38A1 GPR65 SIDT1 ABCB1

5.97e-05189504c604da558c9f4055fb36218452463539f2a73223
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR65 CYSLTR1 IL1B RYR1

5.97e-05189504a438c64a893d43f781ede42e1c7b615b74dc76ef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SCN1A SCN2A SCN8A

5.97e-05189504f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GPR65 SIDT1 ABCB1

6.10e-05190504bee6a438e217b2abd57aef2a80a9fe14a298d223
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR65 CYSLTR1 IL1B RYR1

6.10e-05190504e5625feb21915d4545cfad2659745ef180efcb1f
ToppCellPCW_10-12-Immune_Lymphocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GPR65 SIDT1 ABCB1

6.10e-051905049b56763d62e1ed50006a5b90b160c5a82aab515b
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC38A1 GPR65 SIDT1 ABCB1

6.22e-051915045696e2e2db7b898a1c7ab3582ae74cb712dd5bdf
ToppCellIPF-Lymphoid-NK|World / Disease state, Lineage and Cell class

SLC38A1 GNPTAB SIDT1 ABCB1

6.22e-05191504f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SCN2A SCN3A ABCB1

6.35e-051925040bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A1 RELN DTX1 SCN3A

6.35e-051925045e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellASK454|World / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCA3 GPR65 EDEM1 IL1B

6.35e-051925046b047b445a0df0ecdd6d7baf388a0d966a93b3a2
ComputationalNeighborhood of RAB7L1

GPR65 GNPTAB PTGER2

8.20e-0533283GNF2_RAB7L1
ComputationalB lymphoma expression clusters.

GPR65 DTX1 SIDT1 IL1B

1.89e-04112284MODULE_456
ComputationalNeighborhood of PTPN4

GPR65 GNPTAB PTGER2

2.86e-0450283GNF2_PTPN4
ComputationalGenes in the cancer module 237.

GNPTAB PTGER2 ITGAV

4.44e-0458283MODULE_237
Drugfenvalerate

SLC38A1 SCN2A SCN3A IL1B RYR1 ABCB1

6.98e-0897506ctd:C017690
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN8A

1.98e-076503ctd:C475726
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A

5.54e-078503ctd:C489827
DrugZonisamide

SCN1A SCN2A SCN3A

6.63e-0617503DB00909
DrugAC1L1H8O

MLNR IL1B ABCB1 AZIN1

9.16e-0660504CID000005106
Drugphenyltetrazole

CYSLTR1 ABCB1

1.42e-053502CID000087425
Drugglobotriaosylceramide

IL1B ABCB1

1.42e-053502ctd:C018549
Drug24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid

IL1B ABCB1

2.83e-054502ctd:C562251
Druglithocholate-3-O-glucuronide

APOB ABCB1

2.83e-054502CID000126511
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A

2.83e-054502ctd:C501880
DrugSodium

SCN2A SCN3A SCN8A IL1B

3.49e-0584504ctd:D012964
DrugAC1NSZ76

APOB ABCB1

4.71e-055502CID005320215
Drugacetic anhydride

APOB IL1B

4.71e-055502ctd:C031800
Drugverlukast

CYSLTR1 IL1B ABCB1

4.73e-0532503ctd:C059141
Drugcoprostanol

DHCR7 GNPTAB APOB

4.73e-0532503CID000003240
DrugNSC643733

MLNR IL1B ABCB1 AZIN1

5.20e-0593504CID000054688
DrugGlucosamine

DHCR7 GNPTAB APOB EDEM1 IL1B AZIN1

5.93e-05311506ctd:D005944
Drugisotetrandrine

IL1B RYR1 ABCB1 AZIN1

6.13e-0597504CID000005422
Drugfenpropathrin

SCN2A SCN3A

7.05e-056502ctd:C044267
Drugalpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol

CYSLTR1 IL1B

7.05e-056502ctd:C049740
DrugMethylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A

RELN MLNR IL1B PTGER2 NDRG2

7.65e-052005055679_UP
DrugTetrodotoxin

SCN2A SCN3A SCN8A

9.30e-0540503ctd:D013779
DrugOacsa

IL1B ABCB1

9.86e-057502CID006438472
Drugaliskiren

IL1B ABCB1

9.86e-057502ctd:C446481
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN8A

1.18e-0910474DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN8A

1.18e-0910474DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN8A

2.77e-0912474DOID:0060170 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A

5.71e-0622473DOID:2030 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN8A ABCB1

6.15e-06163475DOID:1826 (implicated_via_orthology)
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

7.44e-063472cv:C5575231
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A ABCB1

9.02e-0682474C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A ABCB1

9.02e-0682474C0751111
DiseaseAura

SCN1A SCN2A SCN8A ABCB1

9.02e-0682474C0236018
DiseaseEpilepsy

SCN1A SCN2A SCN8A ABCB1

2.78e-05109474C0014544
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

3.71e-056472C0220669
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

5.19e-057472C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

5.19e-057472C0751057
Diseasefamilial hyperlipidemia (is_implicated_in)

APOB ABCB1

6.91e-058472DOID:1168 (is_implicated_in)
Diseaseobstructive sleep apnea (biomarker_via_orthology)

IL1B ABCB1

6.91e-058472DOID:0050848 (biomarker_via_orthology)
DiseaseFebrile Convulsions

SCN1A SCN2A

8.88e-059472C0009952
Diseaseencephalitis (biomarker_via_orthology)

IL1B ABCB1

8.88e-059472DOID:9588 (biomarker_via_orthology)
Diseasecystic fibrosis (implicated_via_orthology)

EDEM1 ABCB1

8.88e-059472DOID:1485 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

8.88e-059472C3502809
Diseaseearly infantile epileptic encephalopathy (implicated_via_orthology)

UBA5 SCN8A

1.35e-0411472DOID:0050709 (implicated_via_orthology)
DiseaseUlcerative Colitis

GPR65 IL1B ABCB1

1.41e-0463473C0009324
DiseaseAsthma, Aspirin-Induced

CYSLTR1 PTGER2

1.92e-0413472C1319853
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

1.92e-0413472C0751122
Diseasehepatocellular carcinoma (is_implicated_in)

SLC38A1 IL1B ABCB1 AZIN1

1.99e-04181474DOID:684 (is_implicated_in)
DiseaseMyopathy, Centronuclear, Autosomal Dominant

MYF6 RYR1

2.23e-0414472C1834558
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.57e-0415472EFO_0006519
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

2.94e-0416472C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

3.74e-0418472HP_0002373
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A

4.44e-0493473C1535926
Diseaseend stage renal disease (implicated_via_orthology)

IL1B ABCB1

4.63e-0420472DOID:783 (implicated_via_orthology)
Diseaseepilepsy (biomarker_via_orthology)

IL1B ABCB1

5.12e-0421472DOID:1826 (biomarker_via_orthology)
DiseaseNeutropenia

IL1B ABCB1

5.12e-0421472C0027947
Diseasestatus epilepticus (biomarker_via_orthology)

RELN IL1B ABCB1

5.50e-04100473DOID:1824 (biomarker_via_orthology)
DiseaseMajor Depressive Disorder

RELN EDEM1 IL1B ABCB1

6.06e-04243474C1269683
Diseasenephrotic syndrome (biomarker_via_orthology)

APOB IL1B

6.70e-0424472DOID:1184 (biomarker_via_orthology)
DiseaseIntellectual Disability

UBA5 SCN1A DHCR7 SCN3A SCN8A

7.09e-04447475C3714756
DiseaseUnipolar Depression

RELN EDEM1 IL1B ABCB1

7.69e-04259474C0041696
Diseaseobstructive sleep apnea (is_marker_for)

CYSLTR1 IL1B

9.81e-0429472DOID:0050848 (is_marker_for)
Diseaserhinitis (is_implicated_in)

CYSLTR1 IL1B

1.05e-0330472DOID:4483 (is_implicated_in)
DiseaseMarijuana Abuse

IL1B ABCB1

1.05e-0330472C0024809
Diseaseasthma (is_marker_for)

CYSLTR1 IL1B ABCB1

1.07e-03126473DOID:2841 (is_marker_for)
Diseasearteriosclerosis (is_implicated_in)

APOB IL1B

1.12e-0331472DOID:2349 (is_implicated_in)
Diseasefatty liver disease (biomarker_via_orthology)

APOB IL1B

1.27e-0333472DOID:9452 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FGRSFQYMQYGFLSM

TDRD5

161

Q8NAT2
QYMQYGFLSMFEVLN

TDRD5

166

Q8NAT2
NDFQRPAIYYMMSFS

AZIN1

396

O14977
MYLMNFFFLGAATAY

ABCA3

1196

Q99758
SAIMTGSYNNFFRMF

PPP2R2D

361

Q66LE6
FTGNFFYNYMMGIEF

DHCR7

211

Q9UBM7
TFSFTQAMMYFSYAG

ABCB1

941

P08183
QAMMYFSYAGCFRFG

ABCB1

946

P08183
TMKMFLFQFVNYYSS

ANO6

551

Q4KMQ2
MMAYYSGNEDDLFFE

IL1B

11

P01584
KTNYMEYFQEAMLFF

KIF15

411

Q9NS87
MQFAFSYFYYLMSAV

GNPTAB

991

Q3T906
SFGFYKYSNMEFVRM

KIAA0930

231

Q6ICG6
MQMFFYVTLAGSEFF

OR2T4

131

Q8NH00
MMMDLFETGSYFFYL

MYF6

1

P23409
YFAFAMTFFSLATML

PTGER2

111

P43116
FFLMEGGDTMYDFYT

TUBGCP5

726

Q96RT8
QLSMFASGLFYSMYI

MFSD11

76

O43934
GFCYLIYFNSMSQMN

DTX1

146

Q86Y01
MDTTGYGNLRFYFVM

RELN

466

P78509
AYNMTFFPNLMGHYD

FZD6

36

O60353
SSMEFKYDFNSSMLY

APOB

3456

P04114
YYLGMFMNSFAVFQE

CD109

621

Q6YHK3
FMVQMLTGIYFAFYN

FAM126A

236

Q9BYI3
MFAFAYTDLANMYAE

IFIT5

336

Q13325
MSSLYNFTGEQMAAY

ITGAV

291

P06756
EQHFMAGQSVMYYVF

A3GALT2

126

U3KPV4
GMFVFGYDNYMAHAF

EDEM1

136

Q92611
ASQMAAFQDAYNFFY

EFCAB3

46

Q8N7B9
YMVMSLLGHYNNFFF

RYR1

4796

P21817
DSRMMYFSQYFNIVA

MLNR

326

O43193
QMYFFMAFGNTDSYL

OR1L4

101

Q8NGR5
AQMYFFMAFGNTDSY

OR1L6

136

Q8NGR2
SYTGCLTQMYFFLMF

OR1N1

91

Q8NGS0
YFNMMYGDNSFSGLM

MEIOC

721

A2RUB1
PNYTNFQFDTSFMYM

SIDT2

571

Q8NBJ9
AFKYFLQGMGYMASS

NDRG2

306

Q9UN36
FYSFMIMKSNFDETY

SAMD9L

886

Q8IVG5
FGCMTQMFFYAGFAT

OR5AU1

146

Q8NGC0
LGYTSSLSFFFMMFF

SLC38A6

191

Q8IZM9
MAFFNLYLLGYQNSF

TEX49

1

A0A1B0GTD5
MFIYAIFGMSNFAYV

SCN3A

1666

Q9NY46
MFIYAIFGMSNFAYV

SCN1A

1681

P35498
NLYCSIFFMTAMSFF

CYSLTR1

106

Q9Y271
FYLGYNAMQDFFPTM

UBA5

281

Q9GZZ9
PNYSNFQFDTSFMYM

SIDT1

566

Q9NXL6
FLDYEMGEISFYNMA

TRIM75

416

A6NK02
MFIYAIFGMSNFAYV

SCN2A

1671

Q99250
VMFIFSIFGMSNFAY

SCN8A

1661

Q9UQD0
AFLMYMNFYSSTAFL

GPR65

91

Q8IYL9
SQFYMEDSFCHYNMF

ZCCHC4

231

Q9H5U6
NSETYWMTYTFSFFM

XKRX

61

Q6PP77
FGQPLVFDMAYENYM

TRMT10C

201

Q7L0Y3
SNISFFAMFVMYFLT

SLC38A1

311

Q9H2H9
FAMFVMYFLTAIFGY

SLC38A1

316

Q9H2H9