Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	9.23e-11	46	32	6	GO:0030020
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	4.75e-07	188	32	6	GO:0005201
GeneOntologyMolecularFunction	structural molecule activity	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 MAPK8IP2	4.35e-04	891	32	7	GO:0005198
GeneOntologyBiologicalProcess	social behavior	DRD4 CIC NPAS4 TBX1 MAPK8IP2	9.68e-08	74	32	5	GO:0035176
GeneOntologyBiologicalProcess	biological process involved in intraspecies interaction between organisms	DRD4 CIC NPAS4 TBX1 MAPK8IP2	1.11e-07	76	32	5	GO:0051703
GeneOntologyBiologicalProcess	extracellular matrix organization	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 SPINT1	1.46e-06	377	32	7	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 SPINT1	1.49e-06	378	32	7	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 SPINT1	1.52e-06	379	32	7	GO:0045229
GeneOntologyBiologicalProcess	learning	DRD4 ABCA7 CIC NPAS4 MAPK8IP2	1.76e-05	212	32	5	GO:0007612
GeneOntologyBiologicalProcess	excitatory postsynaptic potential	DRD4 GRIN2D NPAS4 MAPK8IP2	4.72e-05	130	32	4	GO:0060079
GeneOntologyBiologicalProcess	MAPK cascade	PER1 CDC42EP5 DRD4 ABCA7 BANK1 TBX1 MAPK8IP2 DUSP8	6.63e-05	930	32	8	GO:0000165
GeneOntologyBiologicalProcess	chemical synaptic transmission, postsynaptic	DRD4 GRIN2D NPAS4 MAPK8IP2	7.62e-05	147	32	4	GO:0099565
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	DRD4 GRIN2D NPAS4 MAPK8IP2	1.67e-04	180	32	4	GO:0060078
GeneOntologyBiologicalProcess	memory	DRD4 ABCA7 CIC NPAS4	1.78e-04	183	32	4	GO:0007613
GeneOntologyBiologicalProcess	regulation of MAPK cascade	PER1 DRD4 ABCA7 BANK1 TBX1 MAPK8IP2 DUSP8	2.08e-04	815	32	7	GO:0043408
GeneOntologyBiologicalProcess	learning or memory	DRD4 ABCA7 CIC NPAS4 MAPK8IP2	2.54e-04	373	32	5	GO:0007611
GeneOntologyBiologicalProcess	skeletal system development	COL3A1 COL18A1 COL9A1 TTC9 TBX1 WNT11	3.21e-04	615	32	6	GO:0001501
GeneOntologyBiologicalProcess	behavior	DRD4 GRIN2D ABCA7 CIC NPAS4 TBX1 MAPK8IP2	3.58e-04	891	32	7	GO:0007610
GeneOntologyBiologicalProcess	artery morphogenesis	COL3A1 TBX1 WNT11	3.88e-04	92	32	3	GO:0048844
GeneOntologyBiologicalProcess	short-term memory	DRD4 NPAS4	3.92e-04	19	32	2	GO:0007614
GeneOntologyBiologicalProcess	response to acid chemical	COL3A1 COL18A1 GRIN2D NPAS4	4.10e-04	228	32	4	GO:0001101
GeneOntologyBiologicalProcess	cognition	DRD4 ABCA7 CIC NPAS4 MAPK8IP2	4.52e-04	423	32	5	GO:0050890
GeneOntologyBiologicalProcess	supramolecular fiber organization	COL3A1 FMN2 CDC42EP5 COL18A1 ZBED3 FHOD1 WNT11	5.50e-04	957	32	7	GO:0097435
GeneOntologyBiologicalProcess	notochord development	COL18A1 WNT11	6.30e-04	24	32	2	GO:0030903
GeneOntologyBiologicalProcess	positive regulation of intracellular signal transduction	COL3A1 BAK1 DRD4 ABCA7 BANK1 TBX1 MAPK8IP2 WNT11	6.53e-04	1299	32	8	GO:1902533
GeneOntologyBiologicalProcess	peptide cross-linking	COL3A1 ABCA7	7.99e-04	27	32	2	GO:0018149
GeneOntologyBiologicalProcess	inhibitory postsynaptic potential	DRD4 NPAS4	7.99e-04	27	32	2	GO:0060080
GeneOntologyBiologicalProcess	secondary palate development	TBX1 WNT11	7.99e-04	27	32	2	GO:0062009
GeneOntologyBiologicalProcess	response to abiotic stimulus	COL3A1 BAK1 PER1 FMN2 COL18A1 GRIN2D ABCA7 WNT11	8.88e-04	1361	32	8	GO:0009628
GeneOntologyCellularComponent	collagen trimer	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	4.73e-09	88	33	6	GO:0005581
GeneOntologyCellularComponent	basement membrane	COL23A1 COL4A4 COL4A5 COL18A1 NTN3	1.30e-06	122	33	5	GO:0005604
GeneOntologyCellularComponent	complex of collagen trimers	COL3A1 COL4A4 COL4A5	4.68e-06	21	33	3	GO:0098644
GeneOntologyCellularComponent	extracellular matrix	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3 WNT11	6.25e-06	656	33	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3 WNT11	6.39e-06	658	33	8	GO:0030312
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.18e-05	332	33	6	GO:0005788
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3	1.56e-05	530	33	7	GO:0062023
GeneOntologyCellularComponent	collagen type IV trimer	COL4A4 COL4A5	3.61e-05	6	33	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A4 COL4A5	6.73e-05	8	33	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A4 COL4A5	6.73e-05	8	33	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A4 COL4A5	6.73e-05	8	33	2	GO:0098645
HumanPheno	Anterior lenticonus	COL4A4 COL4A5	1.52e-05	3	12	2	HP:0011501
HumanPheno	Glomerular basement membrane lamellation	COL4A4 COL4A5	1.52e-05	3	12	2	HP:0030034
MousePheno	renal glomerular synechia	COL4A4 COL4A5	4.14e-05	5	29	2	MP:0011483
MousePheno	podocyte foot process effacement	COL4A4 COL4A5 COL18A1	6.45e-05	38	29	3	MP:0008140
MousePheno	expanded mesangial matrix	COL4A4 COL4A5 COL18A1	1.15e-04	46	29	3	MP:0011353
MousePheno	abnormal mesangial matrix morphology	COL4A4 COL4A5 COL18A1	1.56e-04	51	29	3	MP:0011338
MousePheno	abnormal podocyte foot process morphology	COL4A4 COL4A5 COL18A1	1.96e-04	55	29	3	MP:0008059
Domain	Collagen	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	7.46e-09	85	33	6	PF01391
Domain	Collagen	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	7.46e-09	85	33	6	IPR008160
Domain	C4	COL4A4 COL4A5	4.52e-05	6	33	2	SM00111
Domain	-	COL4A4 COL4A5	4.52e-05	6	33	2	2.170.240.10
Domain	Collagen_VI_NC	COL4A4 COL4A5	4.52e-05	6	33	2	IPR001442
Domain	NC1_IV	COL4A4 COL4A5	4.52e-05	6	33	2	PS51403
Domain	C4	COL4A4 COL4A5	4.52e-05	6	33	2	PF01413
Domain	FH2	FMN2 FHOD1	3.13e-04	15	33	2	PS51444
Domain	FH2_Formin	FMN2 FHOD1	3.13e-04	15	33	2	IPR015425
Domain	FH2	FMN2 FHOD1	3.13e-04	15	33	2	PF02181
Domain	FH2	FMN2 FHOD1	3.13e-04	15	33	2	SM00498
Domain	PAS_fold_3	PER1 NPAS4	7.48e-04	23	33	2	IPR013655
Domain	TSPN	COL18A1 COL9A1	7.48e-04	23	33	2	SM00210
Domain	PAS_3	PER1 NPAS4	7.48e-04	23	33	2	PF08447
Domain	PAS-assoc_C	PER1 NPAS4	8.15e-04	24	33	2	IPR000700
Domain	CTDL_fold	COL4A4 COL4A5 COL18A1	8.80e-04	107	33	3	IPR016187
Domain	PAC	PER1 NPAS4	9.58e-04	26	33	2	PS50113
Domain	PAS	PER1 NPAS4	1.45e-03	32	33	2	SM00091
Domain	PAS	PER1 NPAS4	1.64e-03	34	33	2	IPR000014
Domain	PAS	PER1 NPAS4	1.64e-03	34	33	2	PS50112
Domain	Laminin_G	COL18A1 COL9A1	4.70e-03	58	33	2	IPR001791
Domain	ConA-like_dom	COL18A1 TRIM65 COL9A1	6.70e-03	219	33	3	IPR013320
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	7.02e-11	41	25	6	MM15538
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.10e-10	44	25	6	M27812
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	8.47e-10	61	25	6	MM14637
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.14e-09	64	25	6	M26953
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.51e-09	67	25	6	M26999
Pathway	REACTOME_COLLAGEN_FORMATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	3.28e-09	76	25	6	MM14573
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	6.49e-09	85	25	6	M16441
Pathway	REACTOME_COLLAGEN_FORMATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	9.19e-09	90	25	6	M631
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL3A1 COL4A4 COL4A5 COL18A1 COL9A1	2.30e-08	50	25	5	MM14796
Pathway	REACTOME_NCAM1_INTERACTIONS	COL3A1 COL4A4 COL4A5 COL9A1	3.66e-08	20	25	4	MM15061
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL3A1 COL4A4 COL4A5 COL18A1 COL9A1	6.38e-08	61	25	5	M27103
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.31e-07	140	25	6	M587
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL3A1 COL4A4 COL4A5 COL18A1 COL9A1	1.95e-07	76	25	5	MM14867
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL3A1 COL4A4 COL4A5 COL9A1	5.45e-07	38	25	4	MM14969
Pathway	REACTOME_NCAM1_INTERACTIONS	COL3A1 COL4A4 COL4A5 COL9A1	8.23e-07	42	25	4	M7169
Pathway	PID_SYNDECAN_1_PATHWAY	COL3A1 COL4A4 COL4A5 COL9A1	1.19e-06	46	25	4	M198
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL3A1 COL4A4 COL4A5 COL18A1	2.12e-06	53	25	4	MM14566
Pathway	REACTOME_SIGNALING_BY_PDGF	COL3A1 COL4A4 COL4A5 COL9A1	2.85e-06	57	25	4	MM14713
Pathway	REACTOME_SIGNALING_BY_PDGF	COL3A1 COL4A4 COL4A5 COL9A1	3.06e-06	58	25	4	M2049
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL3A1 COL4A4 COL4A5 COL9A1	4.27e-06	63	25	4	M11187
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	4.69e-06	258	25	6	MM14572
Pathway	PID_INTEGRIN1_PATHWAY	COL3A1 COL4A4 COL4A5 COL18A1	5.15e-06	66	25	4	M18
Pathway	PID_AVB3_INTEGRIN_PATHWAY	COL3A1 COL4A4 COL4A5 COL9A1	8.14e-06	74	25	4	M160
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL3A1 COL4A4 COL4A5 COL9A1	9.06e-06	76	25	4	M27219
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.11e-05	300	25	6	M610
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A4 COL4A5 COL18A1	1.94e-05	30	25	3	M27216
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL3A1 COL4A4 COL4A5	2.36e-05	32	25	3	MM14924
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL3A1 COL4A4 COL4A5 COL18A1	4.50e-05	114	25	4	MM14571
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A4 COL4A5	1.35e-04	10	25	2	M22040
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A4 COL4A5	1.35e-04	10	25	2	MM1560
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL3A1 COL4A4 COL4A5	1.50e-04	59	25	3	M27218
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A4 COL4A5	1.64e-04	11	25	2	M15422
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A4 COL4A5	1.97e-04	12	25	2	MM1526
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A4 COL4A5	2.33e-04	13	25	2	MM1347
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A4 COL4A5	2.33e-04	13	25	2	M12950
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A4 COL4A5	2.71e-04	14	25	2	MM1458
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A4 COL4A5	2.71e-04	14	25	2	M6487
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A4 COL4A5	3.13e-04	15	25	2	M27161
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A4 COL4A5	3.13e-04	15	25	2	MM14922
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL3A1 COL4A4 GP5	4.27e-04	84	25	3	M7098
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A4 COL4A5	4.54e-04	18	25	2	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A4 COL4A5	4.54e-04	18	25	2	MM14882
Pathway	BIOCARTA_AMI_PATHWAY	COL4A4 COL4A5	5.63e-04	20	25	2	M15394
Pathway	WP_SMALL_CELL_LUNG_CANCER	BAK1 COL4A4 COL4A5	6.31e-04	96	25	3	M39834
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	COL3A1 COL4A4 COL4A5 COL9A1 SPINT1	7.28e-04	418	25	5	MM15587
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A4 COL4A5	7.47e-04	23	25	2	M15997
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A4 COL4A5	7.47e-04	23	25	2	MM1427
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	COL3A1 COL4A4 COL4A5 COL9A1	1.07e-03	261	25	4	MM15676
Pathway	WP_22Q112_COPY_NUMBER_VARIATION_SYNDROME	TSKS TBX1 GP5	1.52e-03	130	25	3	M39787
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	COL3A1 COL4A4 COL4A5 COL9A1 SPINT1	2.13e-03	532	25	5	M27870
Pathway	PID_INTEGRIN3_PATHWAY	COL4A4 COL4A5	2.61e-03	43	25	2	M53
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	COL4A4 COL4A5 WNT11	2.80e-03	161	25	3	M39770
Pathway	WP_NEPHROTIC_SYNDROME	COL4A4 COL4A5	2.85e-03	45	25	2	M39864
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL3A1 COL9A1	3.11e-03	47	25	2	MM14925
Pathway	REACTOME_SIGNALING_BY_MET	COL3A1 SPINT1	6.22e-03	67	25	2	MM15345
Pathway	WP_PLEURAL_MESOTHELIOMA	BAK1 COL4A4 COL4A5 WNT11	6.98e-03	439	25	4	M42563
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	COL4A4 COL4A5	7.15e-03	72	25	2	M39403
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	COL4A4 COL4A5	7.35e-03	73	25	2	MM15906
Pathway	REACTOME_SIGNALING_BY_MET	COL3A1 SPINT1	8.56e-03	79	25	2	M27643
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL3A1 COL4A4 COL4A5 COL9A1 TBX1 NTN3 WNT11	1.02e-02	1432	25	7	M509
Pubmed	Membrane-type MMPs are indispensable for placental labyrinth formation and development.	COL3A1 COL18A1 SPINT1	3.08e-07	14	34	3	20858856
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL3A1 COL23A1 COL4A4 COL18A1 COL9A1	3.87e-07	153	34	5	25037231
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1	5.98e-07	167	34	5	22159717
Pubmed	Frequent COL4 mutations in familial microhematuria accompanied by later-onset Alport nephropathy due to focal segmental glomerulosclerosis.	COL4A4 COL4A5	9.28e-07	2	34	2	28632965
Pubmed	The clinical spectrum of type IV collagen mutations.	COL4A4 COL4A5	9.28e-07	2	34	2	9195222
Pubmed	Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background.	COL4A4 COL4A5	9.28e-07	2	34	2	31892712
Pubmed	Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.	COL4A4 COL4A5	2.78e-06	3	34	2	27576055
Pubmed	Novel COL4A5, COL4A4, and COL4A3 mutations in Alport syndrome.	COL4A4 COL4A5	2.78e-06	3	34	2	15954103
Pubmed	Genetic Variants of the COL4A3 , COL4A4 , and COL4A5 Genes Contribute to Thinned Glomerular Basement Membrane Lesions in Sporadic IgA Nephropathy Patients.	COL4A4 COL4A5	2.78e-06	3	34	2	36130833
Pubmed	A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.	COL4A4 COL4A5	2.78e-06	3	34	2	14507670
Pubmed	Genetic diagnosis of Alport syndrome in 16 Chinese families.	COL4A4 COL4A5	2.78e-06	3	34	2	38433557
Pubmed	Alport syndrome: impact of digenic inheritance in patients management.	COL4A4 COL4A5	2.78e-06	3	34	2	27859054
Pubmed	Evidence of digenic inheritance in Alport syndrome.	COL4A4 COL4A5	2.78e-06	3	34	2	25575550
Pubmed	Sixteen novel mutations identified in COL4A3, COL4A4, and COL4A5 genes in Slovenian families with Alport syndrome and benign familial hematuria.	COL4A4 COL4A5	2.78e-06	3	34	2	17396119
Pubmed	A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.	COL4A4 COL4A5	2.78e-06	3	34	2	24522496
Pubmed	Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches.	COL4A4 COL4A5	2.78e-06	3	34	2	7962065
Pubmed	Novel mutations in COL4A3, COL4A4, and COL4A5 in Chinese patients with Alport Syndrome.	COL4A4 COL4A5	2.78e-06	3	34	2	28542346
Pubmed	Autosomal dominant form of type IV collagen nephropathy exists among patients with hereditary nephritis difficult to diagnose clinicopathologically.	COL4A4 COL4A5	2.78e-06	3	34	2	28704582
Pubmed	Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.	COL4A4 COL4A5	2.78e-06	3	34	2	18930919
Pubmed	Integration of Genetic Testing and Pathology for the Diagnosis of Adults with FSGS.	COL4A4 COL4A5	2.78e-06	3	34	2	30647093
Pubmed	Four novel mutations identified in the COL4A3, COL4A4 and COL4A5 genes in 10 families with Alport syndrome.	COL4A4 COL4A5	2.78e-06	3	34	2	38978054
Pubmed	Unbiased next generation sequencing analysis confirms the existence of autosomal dominant Alport syndrome in a relevant fraction of cases.	COL4A4 COL4A5	2.78e-06	3	34	2	24033287
Pubmed	Characterization of assembly of recombinant type IV collagen alpha3, alpha4, and alpha5 chains in transfected cell strains.	COL4A4 COL4A5	2.78e-06	3	34	2	14633121
Pubmed	Alport Syndrome	COL4A4 COL4A5	2.78e-06	3	34	2	20301386
Pubmed	Npas4-mediated dopaminergic regulation of safety memory consolidation.	DRD4 NPAS4	5.56e-06	4	34	2	37379214
Pubmed	Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs.	COL3A1 COL9A1	5.56e-06	4	34	2	2054384
Pubmed	Physical and linkage mapping of the human and murine genes for the alpha 1 chain of type IX collagen (COL9A1).	COL3A1 COL9A1	5.56e-06	4	34	2	8244386
Pubmed	FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.	COL23A1 COL4A5 COL18A1	7.62e-06	39	34	3	33580754
Pubmed	Stability related bias in residues replacing glycines within the collagen triple helix (Gly-Xaa-Yaa) in inherited connective tissue disorders.	COL3A1 COL4A5	9.26e-06	5	34	2	15365990
Pubmed	Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.	COL4A4 COL4A5	1.39e-05	6	34	2	10534397
Pubmed	Stimulation of extracellular matrix components in the normal brain by invading glioma cells.	COL4A4 COL4A5	1.39e-05	6	34	2	9506531
Pubmed	Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain.	COL18A1 WNT11	1.39e-05	6	34	2	36623578
Pubmed	HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.	COL4A4 COL4A5	1.39e-05	6	34	2	7495302
Pubmed	ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.	COL3A1 COL9A1	1.39e-05	6	34	2	17029294
Pubmed	A tumor derived motility factor that stimulates cell migration on extracellular matrix.	COL4A4 COL4A5	1.39e-05	6	34	2	9673377
Pubmed	Extracellular matrix of the human optic nerve head.	COL4A4 COL4A5	1.39e-05	6	34	2	2426947
Pubmed	Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.	COL4A5 COL18A1	1.39e-05	6	34	2	25840998
Pubmed	Angiogenesis and collagen type IV expression in different endothelial cell culture systems.	COL4A4 COL4A5	1.39e-05	6	34	2	23551189
Pubmed	Monoclonal antibody to human basement membrane collagen type IV.	COL4A4 COL4A5	1.39e-05	6	34	2	6811420
Pubmed	Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.	COL4A4 COL4A5	1.39e-05	6	34	2	11732842
Pubmed	Developmental distribution of collagen IV isoforms and relevance to ocular diseases.	COL4A4 COL4A5	1.39e-05	6	34	2	19275937
Pubmed	Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.	COL4A4 COL4A5	1.39e-05	6	34	2	6988303
Pubmed	Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.	COL4A4 COL4A5	1.39e-05	6	34	2	6389236
Pubmed	Collagen IV in the developing lens capsule.	COL4A4 COL4A5	1.39e-05	6	34	2	12225806
Pubmed	Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.	COL4A4 COL4A5	1.94e-05	7	34	2	10639489
Pubmed	Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.	COL4A4 COL4A5	1.94e-05	7	34	2	7521231
Pubmed	Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.	COL4A4 COL4A5	1.94e-05	7	34	2	11711546
Pubmed	Regulation of protease nexin-1 target protease specificity by collagen type IV.	COL4A4 COL4A5	1.94e-05	7	34	2	8006028
Pubmed	Corneal cell proteins and ocular surface pathology.	COL4A4 COL4A5	1.94e-05	7	34	2	10416788
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A4 COL4A5	1.94e-05	7	34	2	10716744
Pubmed	Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.	COL4A4 COL4A5	1.94e-05	7	34	2	1724753
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL3A1 COL4A4 COL4A5 COL18A1	2.55e-05	175	34	4	28071719
Pubmed	Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis.	COL3A1 COL9A1	2.59e-05	8	34	2	9164858
Pubmed	Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1.	COL3A1 COL9A1	2.59e-05	8	34	2	8088797
Pubmed	Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.	COL4A4 COL4A5	2.59e-05	8	34	2	10382266
Pubmed	Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.	COL4A4 COL4A5	2.59e-05	8	34	2	11683410
Pubmed	Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.	COL4A4 COL4A5	2.59e-05	8	34	2	3997552
Pubmed	Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.	COL4A4 COL4A5	2.59e-05	8	34	2	29422532
Pubmed	Mice develop normally without tenascin.	COL4A4 COL4A5	2.59e-05	8	34	2	1383086
Pubmed	Zbed3 participates in the subcortical maternal complex and regulates the distribution of organelles.	FMN2 ZBED3	2.59e-05	8	34	2	28992324
Pubmed	MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?	COL4A4 COL4A5	3.33e-05	9	34	2	9878537
Pubmed	Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.	COL4A4 COL4A5	3.33e-05	9	34	2	8562707
Pubmed	Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.	COL4A4 COL4A5	3.33e-05	9	34	2	12101409
Pubmed	Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.	COL4A4 COL4A5	3.33e-05	9	34	2	35499085
Pubmed	Characterization of binding properties of the myelin-associated glycoprotein to extracellular matrix constituents.	COL3A1 COL9A1	4.15e-05	10	34	2	2446864
Pubmed	Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis.	TBX1 WNT11	4.15e-05	10	34	2	16687132
Pubmed	Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.	COL4A4 COL4A5	4.15e-05	10	34	2	9136074
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	COL4A4 COL4A5	4.15e-05	10	34	2	9415455
Pubmed	Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.	COL4A4 COL4A5	5.07e-05	11	34	2	14998921
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A4 COL4A5	5.07e-05	11	34	2	7500359
Pubmed	HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.	BAK1 GRIN2D	5.07e-05	11	34	2	24739951
Pubmed	Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.	COL4A4 COL4A5	5.07e-05	11	34	2	9731539
Pubmed	Chromosomal localization of opioid peptide and receptor genes in the mouse.	COL3A1 COL9A1	6.08e-05	12	34	2	7752808
Pubmed	Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.	COL4A4 COL4A5	6.08e-05	12	34	2	8918877
Pubmed	Basement membrane fragility underlies embryonic lethality in fukutin-null mice.	COL4A4 COL4A5	6.08e-05	12	34	2	15837576
Pubmed	Cardiac progenitors instruct second heart field fate through Wnts.	TBX1 WNT11	6.08e-05	12	34	2	36649430
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A4 COL4A5	6.08e-05	12	34	2	12180907
Pubmed	Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.	COL4A4 COL4A5	6.08e-05	12	34	2	16024816
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL4A4 COL4A5 COL18A1	6.42e-05	79	34	3	18757743
Pubmed	Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.	TBX1 WNT11	7.19e-05	13	34	2	24821700
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A4 COL4A5	7.19e-05	13	34	2	9833687
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FBRSL1 PER1 COL4A5 GRIN2D ZBED3 ABCA7 CIC	8.14e-05	1105	34	7	35748872
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMN2 FHOD1	8.38e-05	14	34	2	26272686
Pubmed	Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.	COL4A4 COL4A5	8.38e-05	14	34	2	12878203
Pubmed	Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.	COL4A4 COL4A5	8.38e-05	14	34	2	19858219
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A4 COL4A5	9.66e-05	15	34	2	10625553
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A4 COL4A5	9.66e-05	15	34	2	9264260
Pubmed	Collagen II is essential for the removal of the notochord and the formation of intervertebral discs.	COL3A1 COL9A1	9.66e-05	15	34	2	9832566
Pubmed	Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.	COL4A4 COL4A5	9.66e-05	15	34	2	10706142
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	COL4A4 COL4A5	1.10e-04	16	34	2	15878328
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	COL4A4 COL4A5	1.25e-04	17	34	2	18082680
Pubmed	LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation.	TBX1 WNT11	1.41e-04	18	34	2	32901292
Pubmed	Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.	COL4A4 COL4A5	1.41e-04	18	34	2	9160753
Pubmed	Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract.	TBX1 WNT11	1.41e-04	18	34	2	16839542
Pubmed	FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.	COL18A1 WNT11	1.57e-04	19	34	2	23616926
Pubmed	Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.	COL4A4 COL4A5	1.57e-04	19	34	2	15689378
Pubmed	A single cell transcriptional atlas of early synovial joint development.	COL3A1 COL9A1	1.74e-04	20	34	2	32580935
Pubmed	Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism.	TBX1 WNT11	1.74e-04	20	34	2	21145505
Pubmed	A high-resolution anatomical ontology of the developing murine genitourinary tract.	COL9A1 WNT11	1.93e-04	21	34	2	17452023
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	COL3A1 COL4A4	1.93e-04	21	34	2	27856617
GeneFamily	Collagens	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.89e-11	46	23	6	490
Coexpression	NABA_COLLAGENS	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	1.76e-11	43	34	6	MM17060
Coexpression	NABA_COLLAGENS	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1	2.04e-11	44	34	6	M3005
Coexpression	NABA_CORE_MATRISOME	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3	4.83e-08	270	34	7	MM17057
Coexpression	NABA_CORE_MATRISOME	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3	5.47e-08	275	34	7	M5884
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A4 COL4A5 COL18A1 NTN3	2.09e-07	40	34	4	M5887
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	COL3A1 COL4A4 COL4A5	3.47e-06	23	34	3	M48001
Coexpression	BENPORATH_ES_WITH_H3K27ME3	COL4A5 C2CD4A DRD4 GRIN2D NPAS4 TBX1 MAPK8IP2 WNT11 DUSP8	8.85e-06	1115	34	9	M10371
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS_TUMOR_CELL_DERIVED	COL3A1 COL4A4	2.44e-05	6	34	2	M48000
Coexpression	NABA_MATRISOME	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3 WNT11	3.46e-05	1008	34	8	MM17056
Coexpression	NABA_MATRISOME	COL3A1 COL23A1 COL4A4 COL4A5 COL18A1 COL9A1 NTN3 WNT11	3.93e-05	1026	34	8	M5889
Coexpression	DCA_UP.V1_UP	GRIN2D TSKS NTN3 MAPK8IP2	9.64e-05	186	34	4	M2762
Coexpression	KIM_GERMINAL_CENTER_T_HELPER_DN	PER1 DUSP8	1.07e-04	12	34	2	M1408
Coexpression	GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP	GRIN2D TSKS CIC MAPK8IP2	1.18e-04	196	34	4	M7616
Coexpression	GSE3982_EOSINOPHIL_VS_MAST_CELL_UP	TTC9 ABCA7 TBX1 DUSP8	1.25e-04	199	34	4	M5397
Coexpression	ZHONG_PFC_C3_ASTROCYTE	FBRSL1 COL18A1 PDCD7 CIC MAPK8IP2	1.37e-04	389	34	5	M39102
Coexpression	FRASOR_RESPONSE_TO_ESTRADIOL_DN	BAK1 COL4A5 TTC9	1.42e-04	78	34	3	M3002
Coexpression	DEMAGALHAES_AGING_DN	COL3A1 COL4A5	1.94e-04	16	34	2	M2145
Coexpression	BENPORATH_SUZ12_TARGETS	COL4A5 C2CD4A GRIN2D NPAS4 TBX1 MAPK8IP2 WNT11	3.10e-04	1035	34	7	M9898
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL4A4 COL4A5 COL18A1 ABCA7 DUSP8	2.66e-07	183	34	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 CDC42EP5 COL18A1 TTC9 TBX1	3.47e-07	193	34	5	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 CDC42EP5 COL18A1 C2CD4A	6.25e-06	158	34	4	32c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL4A4 CDC42EP5 TSKS	6.41e-06	159	34	4	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL4A4 CDC42EP5 TSKS	6.41e-06	159	34	4	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBRSL1 ZNF385C SPINT1 WNT11	7.42e-06	165	34	4	479962ce1c3d6636ae62b6709635299748653801
ToppCell	facs-Spleen-nan-24m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4A SPINT1 DUSP8 GP5	7.78e-06	167	34	4	16bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCell	facs-Spleen-nan-24m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4A SPINT1 DUSP8 GP5	7.78e-06	167	34	4	515988c7035c550a2f072430d9d7027869593d17
ToppCell	facs-Spleen-nan-24m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4A SPINT1 DUSP8 GP5	7.78e-06	167	34	4	f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDC42EP5 COL18A1 TTC9 TBX1	9.58e-06	176	34	4	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL3A1 CDC42EP5 COL18A1 C2CD4A	1.05e-05	180	34	4	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL18A1 SPINT1 WNT11	1.17e-05	185	34	4	6da9a06e1514d5d5f47359a14637f02539846096
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 COL18A1 TTC9 TBX1	1.17e-05	185	34	4	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL18A1 SPINT1 WNT11	1.17e-05	185	34	4	4a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 COL18A1 TTC9 TBX1	1.17e-05	185	34	4	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42EP5 COL18A1 TTC9 TBX1	1.22e-05	187	34	4	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42EP5 COL18A1 TTC9 TBX1	1.22e-05	187	34	4	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL18A1 TTC9 SPINT1 TBX1	1.24e-05	188	34	4	c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL23A1 COL18A1 TTC9 TBX1	1.29e-05	190	34	4	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL23A1 COL4A5 NPAS4 DUSP8	1.29e-05	190	34	4	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL23A1 COL18A1 TTC9 TBX1	1.29e-05	190	34	4	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL23A1 COL18A1 TTC9 TBX1	1.29e-05	190	34	4	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 COL18A1 TTC9 TBX1	1.32e-05	191	34	4	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER1 COL23A1 COL18A1 TTC9	1.32e-05	191	34	4	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 COL18A1 TTC9 TBX1	1.32e-05	191	34	4	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	COL3A1 CDC42EP5 COL18A1 WNT11	1.40e-05	194	34	4	638b9fdce64ed00243b5303800ec66207d5fd640
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	COL3A1 CDC42EP5 COL18A1 WNT11	1.40e-05	194	34	4	e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	COL3A1 COL23A1 COL4A5 COL9A1	1.58e-05	200	34	4	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL3A1 COL23A1 COL4A5 COL9A1	1.58e-05	200	34	4	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBED3 BANK1 CIC	5.71e-05	98	34	3	95162072f3afc95e46f29db3d79ebd930bc09726
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL4A5 COL18A1	7.42e-05	107	34	3	13af691c8533418d2800a8eca61155896b559948
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL4A5 COL18A1	7.42e-05	107	34	3	a5a34bb9706527799ddb494d4f1bfc634c29e8a9
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL4A4 COL4A5 COL18A1	1.07e-04	121	34	3	5035e071033cb76a7fc0128716755b14821e8f05
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL4A4 COL4A5 COL18A1	1.07e-04	121	34	3	c96115bd33455296378a257583b49442d00b39ca
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMN2 COL9A1 WNT11	1.26e-04	128	34	3	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	COL3A1 CDC42EP5 COL18A1	1.44e-04	134	34	3	a3547a68012d879d4dfe80394eace70808722e43
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL4A5 COL18A1	1.44e-04	134	34	3	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Striatum / BrainAtlas - Mouse McCarroll V32	COL3A1 CDC42EP5 COL18A1	1.44e-04	134	34	3	9458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL3A1 CDC42EP5 WNT11	1.79e-04	144	34	3	1c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL23A1 COL4A5	2.14e-04	153	34	3	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL23A1 COL4A5	2.14e-04	153	34	3	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL23A1 COL4A5	2.14e-04	153	34	3	2513edfae62a44e51d3556675a096723194c966c
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN2 SPINT1 TBX1	2.18e-04	154	34	3	1e32969bee810adaf2d560f0824a16227df513d8
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL3A1 COL4A5 COL18A1	2.18e-04	154	34	3	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF385C BANK1 CIC	2.30e-04	157	34	3	d12f343454202da86a06d0369f8ffe5662cd091b
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 ZNF385C TBX1	2.30e-04	157	34	3	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL23A1 COL4A4	2.39e-04	159	34	3	2607b562903228274fbd96168ba826782fab0b53
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL23A1 COL4A4	2.39e-04	159	34	3	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL3A1 COL23A1 COL4A5	2.39e-04	159	34	3	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL3A1 COL4A5 COL18A1	2.39e-04	159	34	3	34c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL4A5 COL18A1	2.39e-04	159	34	3	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 TTC9 TBX1	2.48e-04	161	34	3	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 TTC9 TBX1	2.48e-04	161	34	3	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 TTC9 TBX1	2.48e-04	161	34	3	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBRSL1 SPINT1 WNT11	2.53e-04	162	34	3	8a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCell	facs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 TSKS DUSP8	2.53e-04	162	34	3	14e9f8aaba308619eb9da90796c336e76cedac1f
ToppCell	facs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 TSKS DUSP8	2.53e-04	162	34	3	860ebf2390b4ad86475ad54717cbefcf61cd3b2a
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_memory\|bone_marrow / Manually curated celltypes from each tissue	COL3A1 COL4A4 BANK1	2.57e-04	163	34	3	30f5c93c4e170304d701b5231f0d545f404066f7
ToppCell	P07-Endothelial-lymphatic_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL23A1 TTC9 TBX1	2.57e-04	163	34	3	5cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCell	P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL23A1 TTC9 TBX1	2.57e-04	163	34	3	322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL4A5 COL9A1	2.62e-04	164	34	3	a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell	BAL-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	COL4A4 ZNF385C TBX1	2.62e-04	164	34	3	4bd9629d054545d1e3f9e5c127b5ac2388637106
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF385C BANK1 MAPK8IP2	2.67e-04	165	34	3	83095377aedf960c05baa523869bdbd2b0a05f2d
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DRD4 ZNF385C ABCA7	2.71e-04	166	34	3	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A4 C2CD4A TBX1	2.71e-04	166	34	3	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A4 C2CD4A TBX1	2.71e-04	166	34	3	eb8d972326a734549675307e411fc795af66da70
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL4A4 SPINT1 ABCA7	2.76e-04	167	34	3	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	DRD4 ZNF385C ZBED3	2.81e-04	168	34	3	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	10x5'-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	DRD4 ZNF385C GP5	2.81e-04	168	34	3	90f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBRSL1 ZNF385C SPINT1	2.81e-04	168	34	3	2c996d09b6a8ccd3c708146eca310b02eafff425
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL23A1 COL4A4	2.81e-04	168	34	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	Endothelial-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CDC42EP5 COL18A1 TBX1	2.86e-04	169	34	3	95c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 BAK1 DUSP8	2.86e-04	169	34	3	7cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 TTC9 TBX1	3.01e-04	172	34	3	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 TTC9 TBX1	3.01e-04	172	34	3	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBRSL1 SPINT1 GP5	3.01e-04	172	34	3	b043d4f81dced7fb3326043f68474123be47cc5d
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL23A1 TTC9 TBX1	3.01e-04	172	34	3	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	COL23A1 COL18A1 TBX1	3.01e-04	172	34	3	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL3A1 COL4A5 WNT11	3.06e-04	173	34	3	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL23A1 CDC42EP5 TBX1	3.06e-04	173	34	3	03b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL23A1 CDC42EP5 TBX1	3.06e-04	173	34	3	12da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell\|TCGA-Thryoid / Sample_Type by Project: Shred V9	COL3A1 C2CD4A SPINT1	3.06e-04	173	34	3	2e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBRSL1 SPINT1 GP5	3.06e-04	173	34	3	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	PND28-Endothelial-Endothelial_lymphatic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL23A1 CDC42EP5 TBX1	3.06e-04	173	34	3	2978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL23A1 CDC42EP5 TBX1	3.06e-04	173	34	3	23d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 NTN3 DUSP8	3.11e-04	174	34	3	c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 CDC42EP5 TBX1	3.17e-04	175	34	3	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 COL4A5 FMN2	3.17e-04	175	34	3	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 TTC9 TBX1	3.17e-04	175	34	3	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 CDC42EP5 TBX1	3.17e-04	175	34	3	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBRSL1 C1orf216 WNT11	3.17e-04	175	34	3	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBRSL1 C1orf216 WNT11	3.17e-04	175	34	3	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL23A1 TTC9 TBX1	3.17e-04	175	34	3	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL23A1 CDC42EP5 WNT11	3.22e-04	176	34	3	cc6f65a7d2c622841c9d1ab3755586039d4ccc4d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL23A1 CDC42EP5 WNT11	3.22e-04	176	34	3	e9152defb4fd41267fb33c42c01fd0c683280783
ToppCell	severe-B_memory\|World / disease stage, cell group and cell class	COL4A4 BANK1 DUSP8	3.22e-04	176	34	3	4e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL23A1 CDC42EP5 WNT11	3.22e-04	176	34	3	a4d269075aa0efc46fa251b379f334e50c69391d
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAK1 COL4A4 TTC9	3.27e-04	177	34	3	164ffbbf798defa3728197deb1a14b661490e525
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A4 COL4A5 FHOD1	3.27e-04	177	34	3	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BAK1 COL4A4 COL18A1	3.33e-04	178	34	3	693f1135d9c5545945e80c7ba3d098afc0ccac29
Computational	Adhesion molecules.	COL3A1 COL4A5 COL18A1 COL9A1	1.17e-04	141	20	4	MODULE_122
Drug	GK-101	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.99e-09	36	34	5	CID000161853
Drug	Madecassol	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	7.17e-09	46	34	5	CID000108062
Drug	d-indobufen	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.10e-08	50	34	5	CID000044562
Drug	ridogrel	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.35e-08	52	34	5	CID005362391
Drug	NSC49633	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.49e-08	53	34	5	CID000023340
Drug	PPACK	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1 GP5	1.57e-08	113	34	6	CID003036757
Drug	AC1LAKND	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	3.33e-08	62	34	5	CID000470146
Drug	PCR 4099	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1 GP5	5.43e-08	139	34	6	CID000002806
Drug	BAPN	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	6.63e-08	71	34	5	CID000001647
Drug	malotilate	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	6.63e-08	71	34	5	CID000004006
Drug	AC1NMZ1B	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	8.75e-08	75	34	5	CID005034185
Drug	strontium ranelate	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	9.99e-08	77	34	5	CID006918182
Drug	halofuginone lactate	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.65e-07	85	34	5	CID000062891
Drug	4-hydroxyproline	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	2.32e-07	91	34	5	CID000000825
Drug	ticlopidine	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	4.31e-07	103	34	5	CID000005472
Drug	hydroxylysine	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	5.71e-07	109	34	5	CID000001029
Drug	AC1L1C2F	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	5.98e-07	110	34	5	CID000001711
Drug	AC1L9732	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	7.14e-07	114	34	5	CID000439300
Drug	Tranilast sodium	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	7.46e-07	115	34	5	CID000005527
Drug	Selara	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.13e-06	125	34	5	CID000150310
Drug	DMSe	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.48e-06	132	34	5	CID000020796
Drug	pirfenidone	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.84e-06	138	34	5	CID000040632
Drug	DL-penicillamine	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.90e-06	139	34	5	CID000004727
Drug	candesartan cilexetil	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	2.34e-06	145	34	5	CID000002540
Drug	L-lysyl-L-lysyl-L-lysine	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	4.04e-06	162	34	5	CID000072363
Drug	khellin	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	5.26e-06	171	34	5	CID000003828
Drug	AC1L1DD6	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	6.57e-06	179	34	5	CID000002299
Drug	12(S)-hydroxyeicosatetraenoic acid	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	8.56e-06	189	34	5	CID000001413
Drug	foscarnet	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	8.78e-06	190	34	5	CID000003414
Drug	AC1Q6PCP	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	2.21e-05	230	34	5	CID000005267
Drug	prostacyclin sodium salt	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	3.29e-05	250	34	5	CID000000159
Drug	hyaluronan	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	4.19e-05	263	34	5	CID000024759
Drug	Y-27632	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1 FHOD1	4.50e-05	444	34	6	CID000005711
Drug	silibinin	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	6.13e-05	285	34	5	CID000005213
Drug	1h00	COL3A1 COL9A1 DRD4	7.99e-05	56	34	3	CID000445950
Drug	(2s,5s)-5-Carboxymethylproline	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	9.68e-05	314	34	5	CID000447989
Drug	AC1L18QD	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	1.14e-04	325	34	5	CID000000213
Drug	CI-1041	DRD4 GRIN2D	1.42e-04	12	34	2	CID000156328
Drug	aspirin	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1 GP5	1.66e-04	563	34	6	CID000002244
Drug	L-3,4-dehydroproline	COL3A1 COL23A1 COL18A1	1.76e-04	73	34	3	CID000094284
Drug	AC1L1GXT	COL3A1 BAK1 PER1	1.83e-04	74	34	3	CID000003890
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	PER1 COL18A1 PRRC2A CIC	1.90e-04	193	34	4	3262_UP
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; HL60; HT_HG-U133A	PER1 PRRC2A FHOD1 DUSP8	2.02e-04	196	34	4	1294_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; PC3; HT_HG-U133A	COL3A1 TTC9 TBX1 GP5	2.02e-04	196	34	4	4623_UP
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	PER1 ABCA7 PRRC2A MAPK8IP2	2.06e-04	197	34	4	2282_DN
Drug	Methimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A	COL3A1 ABCA7 MAPK8IP2 DUSP8	2.10e-04	198	34	4	4550_DN
Drug	Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A	COL3A1 PER1 TTC9 ABCA7	2.14e-04	199	34	4	3516_UP
Drug	Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A	PER1 TTC9 MAPK8IP2 GP5	2.14e-04	199	34	4	3287_UP
Drug	losartan	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	2.30e-04	378	34	5	CID000003961
Drug	colchine	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	2.44e-04	383	34	5	CID000002833
Drug	DDDs	PER1 TBX1	2.90e-04	17	34	2	CID000014360
Drug	chondroitin sulfate	COL3A1 COL23A1 COL4A5 COL18A1 COL9A1	3.46e-04	413	34	5	CID000024766
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL3A1 COL4A5 COL18A1 COL9A1	2.81e-07	53	31	4	C4707243
Disease	Alport syndrome	COL4A4 COL4A5	3.20e-06	3	31	2	cv:C1567741
Disease	Collagen IV-related nephropathies	COL4A4 COL4A5	3.20e-06	3	31	2	cv:CN076135
Disease	Hematuria, Benign Familial	COL4A4 COL4A5	6.40e-06	4	31	2	C0241908
Disease	Alport Syndrome	COL4A4 COL4A5	6.40e-06	4	31	2	C1567741
Disease	Alport Syndrome, X-Linked	COL4A4 COL4A5	1.07e-05	5	31	2	C1567742
Disease	Alport Syndrome, Autosomal Dominant	COL4A4 COL4A5	1.07e-05	5	31	2	C1567743
Disease	Alport Syndrome, Autosomal Recessive	COL4A4 COL4A5	1.07e-05	5	31	2	C1567744
Disease	myopathy (implicated_via_orthology)	COL4A4 COL4A5 COL18A1	1.76e-05	48	31	3	DOID:423 (implicated_via_orthology)
Disease	collagen disease (implicated_via_orthology)	COL4A4 COL4A5	7.00e-05	12	31	2	DOID:854 (implicated_via_orthology)
Disease	Minimal Brain Dysfunction	DRD4 CIC	2.44e-04	22	31	2	C1321905
Disease	Attention Deficit Disorder	DRD4 CIC	2.44e-04	22	31	2	C0041671
Disease	Renal glomerular disease	COL4A4 COL4A5	2.67e-04	23	31	2	C0268731
Disease	Glomerulopathy Assessment	COL4A4 COL4A5	2.67e-04	23	31	2	C4521256
Disease	Attention deficit hyperactivity disorder	DRD4 CIC	2.91e-04	24	31	2	C1263846
Disease	Hereditary hearing loss and deafness	COL4A4 COL4A5 COL9A1	4.82e-04	146	31	3	cv:C0236038
Disease	sphingolipid measurement	ABCA7 PRRC2A	8.13e-04	40	31	2	EFO_0004622
Disease	end stage renal disease (is_implicated_in)	COL3A1 COL4A4	8.54e-04	41	31	2	DOID:783 (is_implicated_in)
Disease	schizophrenia (is_marker_for)	DRD4 GRIN2D	9.83e-04	44	31	2	DOID:5419 (is_marker_for)
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	FBRSL1 BANK1	1.22e-03	49	31	2	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	PROSTATE CANCER, HEREDITARY, 1	FBRSL1 COL23A1	1.82e-03	60	31	2	C4722327

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPCSPEPGREAPGPE	ZNF385C	186	Q66K41
GSPDPAPCGPAPPGN	BANK1	11	Q8NDB2
AAPCPGPPPGSRANP	FBRSL1	271	Q9HCM7
GPGPPRQECGEPALP	BAK1	6	Q16611
RRPDGPGPPDPGEAP	DUSP8	406	Q13202
SPEPACGTPRGPGPP	C1orf216	126	Q8TAB5
CGTPRGPGPPDPLLP	C1orf216	131	Q8TAB5
PPGPPGLLGRPGEAC	COL4A4	386	P53420
LPDCPAAAGGPPPPQ	ABCA7	1356	Q8IZY2
APAAPRPGPAQPGPC	MAPK8IP2	421	Q13387
CVCPPGPPGRRGKPG	COL23A1	116	Q86Y22
PGPPGLDQPCPVGPD	COL23A1	516	Q86Y22
CPGGVPSPGPPQHRP	PER1	21	O15534
TDAGERPRPPPPGPG	PDCD7	101	Q8N8D1
PGRAGPPGSPCLPGP	COL18A1	766	P39060
PPGSPCLPGPPGLPC	COL18A1	771	P39060
DCAPPAPGLPRGPCG	DRD4	261	P21917
APGLPRGPCGPDCAP	DRD4	266	P21917
PGPPAPADPCHDEGG	NTN3	21	O00634
FCAPLEPRPRPGPGP	NPAS4	191	Q8IUM7
PSDEICEPGPPGPPG	COL4A5	446	P29400
CEPGPPGPPGSPGDK	COL4A5	451	P29400
RHGGGPPPEPRAPPA	CDC42EP5	51	Q6NZY7
PGGDAECPGPRGPPP	GP5	466	P40197
ECPGPRGPPPRPAAD	GP5	471	P40197
PPGPPGAPGPCCGGV	COL3A1	1186	P02461
PPGPPGLPGFCEPAS	COL9A1	891	P20849
GGCPARAPEPGPTGP	FHOD1	371	Q9Y613
DGLPGRPPCPPGAES	FMN2	761	Q9NZ56
PRAPGPATPAAPGCP	C2CD4A	151	Q8NCU7
PGDYPDRGGPPCKPP	PRRC2A	426	P48634
VPCEGPPGSEPPRRP	PRRC2A	1696	P48634
RPPGATCPESPGPGP	CIC	96	Q96RK0
CPGLGPAPTPTPPGR	ZBED3	26	Q96IU2
GPPPAPPGLPAGADC	SPINT1	36	O43278
GCPGPPGSPDKPSRP	TSKS	281	Q9UJT2
PGCSCGPVPGEPPGP	WNT11	136	O96014
DPCAAAAPGAPGPPP	TBX1	51	O43435
GPARDPGPDPGPGPD	TRIM65	76	Q6PJ69
PGPDPGPGPDPAARC	TRIM65	81	Q6PJ69
PPAAGEGQRPPPPLC	TTC9	16	Q92623
GGGAPAAPPPCRAAP	GRIN2D	1086	O15399