Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ig_I-set	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	1.77e-04	190	81	6	IPR013098
Domain	I-set	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	1.77e-04	190	81	6	PF07679
Domain	DZF	ILF3 ZFR	1.84e-04	5	81	2	SM00572
Domain	DZF_dom	ILF3 ZFR	1.84e-04	5	81	2	IPR006561
Domain	DZF	ILF3 ZFR	1.84e-04	5	81	2	PF07528
Domain	DZF	ILF3 ZFR	1.84e-04	5	81	2	PS51703
Domain	FN3	IL13RA1 SPEG OBSCN OBSL1 FNDC4 IL2RB	2.27e-04	199	81	6	PS50853
Domain	Ig-like_fold	IL13RA1 SIGIRR SPEG OBSCN OBSL1 FNDC4 LSAMP LRRC4B KDR IL2RB EXOSC2	2.27e-04	706	81	11	IPR013783
Domain	FN3_dom	IL13RA1 SPEG OBSCN OBSL1 FNDC4 IL2RB	2.95e-04	209	81	6	IPR003961
Domain	IGc2	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	5.50e-04	235	81	6	SM00408
Domain	Ig_sub2	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	5.50e-04	235	81	6	IPR003598
Domain	-	IL13RA1 SIGIRR SPEG OBSCN OBSL1 FNDC4 LSAMP LRRC4B KDR IL2RB	5.75e-04	663	81	10	2.60.40.10
Domain	FN3	SPEG OBSCN OBSL1 FNDC4 IL2RB	1.26e-03	185	81	5	SM00060
Domain	fn3	SPEG OBSCN OBSL1 FNDC4	5.41e-03	162	81	4	PF00041
Domain	IG_LIKE	SIGIRR SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	5.42e-03	491	81	7	PS50835
Domain	Ig-like_dom	SIGIRR SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	6.16e-03	503	81	7	IPR007110
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	2.80e-06	162	84	6	25826454
Pubmed	Plk1 regulates liver tumor cell death by phosphorylation of TAp63.	TP63 PLK1	5.76e-06	2	84	2	19668228
Pubmed	Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44.	CD44 HAS1	5.76e-06	2	84	2	18199543
Pubmed	Alterations in CD44 isoforms and HAS expression in human articular chondrocytes during the de- and re-differentiation processes.	CD44 HAS1	5.76e-06	2	84	2	19148550
Pubmed	Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat.	CD44 HAS1	5.76e-06	2	84	2	24099991
Pubmed	ATDC mediates a TP63-regulated basal cancer invasive program.	TP63 ATM	5.76e-06	2	84	2	30643195
Pubmed	Hyaluronic acid (HA) stimulates the in vitro expression of CD44 proteins but not HAS1 proteins in normal human epidermal keratinocytes (NHEKs) and is HA molecular weight dependent.	CD44 HAS1	5.76e-06	2	84	2	33908161
Pubmed	Targeting the Stromal Pro-Tumoral Hyaluronan-CD44 Pathway in Pancreatic Cancer.	CD44 HAS1	5.76e-06	2	84	2	33921242
Pubmed	Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance.	TP63 ATM	5.76e-06	2	84	2	22951905
Pubmed	Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.	ATM PLK1	5.76e-06	2	84	2	17121863
Pubmed	ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage.	TP63 ATM	5.76e-06	2	84	2	18769144
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	5.76e-06	2	84	2	15185077
Pubmed	Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions.	CD44 IL2RB	5.76e-06	2	84	2	19265164
Pubmed	CD44, γ-H2AX, and p-ATM Expressions in Short-Term Ex Vivo Culture of Tumour Slices Predict the Treatment Response in Patients with Oral Squamous Cell Carcinoma.	CD44 ATM	5.76e-06	2	84	2	35055060
Pubmed	Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation.	KDR PLK1	5.76e-06	2	84	2	20170163
Pubmed	Polo-like kinase 1 inactivation following mitotic DNA damaging treatments is independent of ataxia telangiectasia mutated kinase.	ATM PLK1	5.76e-06	2	84	2	15280449
Pubmed	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.	ATRIP TTI1 ATM	1.28e-05	19	84	3	20801936
Pubmed	Analysis of human hyaluronan synthase gene transcriptional regulation and downstream hyaluronan cell surface receptor mobility in myofibroblast differentiation.	CD44 HAS1	1.73e-05	3	84	2	25325984
Pubmed	The phenotypic radiation resistance of CD44+/CD24(-or low) breast cancer cells is mediated through the enhanced activation of ATM signaling.	CD44 ATM	1.73e-05	3	84	2	21935375
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATRIP ATM	1.73e-05	3	84	2	18344416
Pubmed	Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination.	ATM PLK1	1.73e-05	3	84	2	33450211
Pubmed	Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinoma.	CD44 MUC16	1.73e-05	3	84	2	12893366
Pubmed	The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man.	KDR VEGFD	1.73e-05	3	84	2	11279005
Pubmed	ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.	ATM PLK1	1.73e-05	3	84	2	28607002
Pubmed	ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis.	TP63 CD44	1.73e-05	3	84	2	27494839
Pubmed	Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.	OBSCN OBSL1	1.73e-05	3	84	2	20133654
Pubmed	Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair.	ATM RAD54L	1.73e-05	3	84	2	19061978
Pubmed	Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine.	TP63 KDR	1.73e-05	3	84	2	32993587
Pubmed	Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis.	KDR VEGFD	1.73e-05	3	84	2	11574540
Pubmed	Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).	KDR VEGFD	1.73e-05	3	84	2	9435229
Pubmed	Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.	OBSCN OBSL1	1.73e-05	3	84	2	27989621
Pubmed	SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63.	TP63 SPATA18	1.73e-05	3	84	2	21300779
Pubmed	Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.	ATM PLK1	1.73e-05	3	84	2	20581453
Pubmed	Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.	OBSCN OBSL1	1.73e-05	3	84	2	31098411
Pubmed	Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.	OBSCN OBSL1	1.73e-05	3	84	2	20489725
Pubmed	A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.	CD44 KDR	1.73e-05	3	84	2	19773544
Pubmed	Structure of the Human TELO2-TTI1-TTI2 Complex.	TTI1 ATM	3.45e-05	4	84	2	34838521
Pubmed	α6 Integrin and CD44 enrich for a primary keratinocyte population that displays resistance to UV-induced apoptosis.	TP63 CD44	3.45e-05	4	84	2	23071680
Pubmed	Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells.	CD44 HAS1	3.45e-05	4	84	2	23129777
Pubmed	Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2.	KDR VEGFD	3.45e-05	4	84	2	17242158
Pubmed	CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells.	ATRIP ATM	3.45e-05	4	84	2	20048340
Pubmed	Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain.	ATM PLK1	3.45e-05	4	84	2	11901158
Pubmed	Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.	BCL6 STAT4	3.45e-05	4	84	2	24489092
Pubmed	Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.	ATM RAD54L	3.45e-05	4	84	2	16520463
Pubmed	Hyaluronan synthase induction and hyaluronan accumulation in mouse epidermis following skin injury.	CD44 HAS1	3.45e-05	4	84	2	15854028
Pubmed	Chk2 activation and phosphorylation-dependent oligomerization.	ATM PLK1	5.74e-05	5	84	2	12024051
Pubmed	WAC Promotes Polo-like Kinase 1 Activation for Timely Mitotic Entry.	PLK1 WAC	5.74e-05	5	84	2	30021153
Pubmed	Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma.	KDR VEGFD	5.74e-05	5	84	2	18609713
Pubmed	Neuroblastoma progression correlates with downregulation of the lymphangiogenesis inhibitor sVEGFR-2.	KDR VEGFD	5.74e-05	5	84	2	20179233
Pubmed	A role for E1B-AP5 in ATR signaling pathways during adenovirus infection.	ATRIP ATM	5.74e-05	5	84	2	18480432
Pubmed	Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.	TP63 CD44	5.74e-05	5	84	2	18662989
Pubmed	VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption.	KDR VEGFD	5.74e-05	5	84	2	26459520
Pubmed	Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody.	ATM PLK1	5.74e-05	5	84	2	12493754
Pubmed	Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.	ATM PLK1	5.74e-05	5	84	2	12242661
Pubmed	Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.	ATM PLK1	5.74e-05	5	84	2	10973490
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RPAP1 NTMT1 ADGRB1 OBSCN DNAH2 ATM AGPS BIRC6 USP20	7.25e-05	736	84	9	29676528
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	IRS4 BEAN1 TP63 ARHGEF18 ZFR KDR ATM	8.40e-05	430	84	7	35044719
Pubmed	The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.	KDR VEGFD	8.59e-05	6	84	2	25061878
Pubmed	Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway.	TP63 ATM	8.59e-05	6	84	2	24482479
Pubmed	Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.	KDR ATM	8.59e-05	6	84	2	27438146
Pubmed	bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.	CD44 HAS1	8.59e-05	6	84	2	19577615
Pubmed	Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.	ATRIP ATM	8.59e-05	6	84	2	15210935
Pubmed	Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress.	ATRIP ATM	8.59e-05	6	84	2	18583959
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	IARS2 GTPBP2 LIPE CD44 MUC16 ZFR AGPS ANKRD50 BIRC6	1.09e-04	777	84	9	35844135
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ILF3 ATRIP ZFR ATM KDM1B PLK1 ABHD12	1.16e-04	453	84	7	29656893
Pubmed	DNA repair gene polymorphisms and risk of pancreatic cancer.	ATM RAD54L	1.20e-04	7	84	2	19147782
Pubmed	Diagnostic and prognostic tissuemarkers in clear cell and papillary renal cell carcinoma.	CD44 KDR	1.20e-04	7	84	2	21694464
Pubmed	Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality.	KDR BIRC6	1.20e-04	7	84	2	15887267
Pubmed	SCA-1/Ly6A Mesodermal Skeletal Progenitor Subpopulations Reveal Differential Commitment of Early Limb Bud Cells.	CD44 KDR	1.20e-04	7	84	2	34336823
Pubmed	p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes.	TP63 ATM	1.20e-04	7	84	2	28617799
Pubmed	Centrosomal localization of DNA damage checkpoint proteins.	ATRIP ATM	1.20e-04	7	84	2	17171639
Pubmed	Transgenic mouse models in angiogenesis and cardiovascular disease.	KDR VEGFD	1.20e-04	7	84	2	10685072
Pubmed	Systematic identification of NF90 target RNAs by iCLIP analysis.	IL13RA1 ILF3 ZFR	1.36e-04	41	84	3	35013429
Pubmed	Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB.	CD44 HAS1	1.60e-04	8	84	2	17324121
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	TTI1 ATM	1.60e-04	8	84	2	20810650
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2C ARHGEF18 SPIDR SCIN BIRC6 USP20 WAC	1.95e-04	493	84	7	15368895
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	GTPBP2 ATRIP RRP12 ATP6V0A4 OBSL1 ZFR PLK1	2.02e-04	496	84	7	31343991
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CLASP1 SPEG RRP12 OBSCN ZFR ATM PLK1	2.05e-04	497	84	7	36774506
Pubmed	Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos.	KDR VEGFD	2.05e-04	9	84	2	15601856
Pubmed	Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth.	TP63 CD44	2.05e-04	9	84	2	22662233
Pubmed	Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis.	TP63 ATM	2.05e-04	9	84	2	20975950
Pubmed	Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.	TTI1 ATM	2.05e-04	9	84	2	24657168
Pubmed	Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD.	KDR VEGFD	2.05e-04	9	84	2	27159393
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	IRS4 PTPN14 CLCN7 RRP12 CD44 PPME1 TTI1 PLK1 SCIN BIRC6	2.19e-04	1049	84	10	27880917
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PASK CHCHD3 NAA35 IARS2 PTPN14 ILF3 RPAP1 CLCN7 RRP12 OBSL1 ATM ABHD12	2.34e-04	1487	84	12	33957083
Pubmed	Genetic control of leucocyte--endothelial cell interaction in collagen-induced arthritis.	IL13RA1 CD44	2.56e-04	10	84	2	20223839
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	PASK IARS2 ATRIP CLASP1 KDM1B AGPS BIRC6 ABHD12	2.57e-04	686	84	8	28380382
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	PASK CHCHD3 GTPBP2 RRP12 OBSL1 ZFR	2.58e-04	364	84	6	24778252
Pubmed	CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.	NLRP14 TP63 ZP3	2.92e-04	53	84	3	24357321
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	CHCHD3 IARS2 ILF3 RPAP1 ZFR AGPS PLK1 BIRC6	3.05e-04	704	84	8	29955894
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	CHCHD3 PTPN14 CLCN7 ADGRB1 CD44 ANKRD50	3.11e-04	377	84	6	38117590
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	TTI1 ATM	3.13e-04	11	84	2	20427287
Pubmed	Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.	ATRIP ATM	3.13e-04	11	84	2	15758953
Pubmed	The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice.	NTMT1 LSAMP	3.13e-04	11	84	2	39349721
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	TP63 ATM BCL6 PLK1 ABCG8 RAD54L	3.29e-04	381	84	6	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	TP63 ATM BCL6 PLK1 ABCG8 RAD54L	3.34e-04	382	84	6	19170196
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	IL13RA1 CHCHD3 NAA35 GTPBP2 ILF3 PPME1 PABPC4L PLK1 BIRC6 RAD54L WAC	3.46e-04	1327	84	11	32694731
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	ILF3 RPAP1 ARHGEF18 TTI1 ZFR EXOSC2	3.72e-04	390	84	6	17643375
Pubmed	Identification of potential bladder progenitor cells in the trigone.	TP63 CD44	3.75e-04	12	84	2	24992712
Pubmed	Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.	PLK1 BIRC6	3.75e-04	12	84	2	18329369
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SPEG OBSCN OBSL1 LSAMP LRRC4B KDR	6.59e-06	161	52	6	593
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|343B / Donor, Lineage, Cell class and subclass (all cells)	TTI1 ACVR2B IL2RB THAP9 TEDC1	1.20e-05	157	84	5	0362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PASK ATM PLK1 RAD54L STAT4	1.81e-05	171	84	5	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CLASP1 TTI1 ACVR2B THAP9 TEDC1	1.97e-05	174	84	5	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IARS2 PTPN14 ATRIP PABPC4L KDM1B	2.32e-05	180	84	5	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IARS2 PTPN14 ATRIP PABPC4L KDM1B	2.32e-05	180	84	5	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IARS2 PTPN14 ATRIP PABPC4L KDM1B	2.32e-05	180	84	5	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPATA18 OBSL1 LSAMP HAS1 SCIN	2.64e-05	185	84	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13RA1 PTPN14 TP63 SCIN VEGFD	2.78e-05	187	84	5	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	facs-Kidney-nan-24m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3KBP1 CD44 IL2RB STAT4 FAM83A	2.78e-05	187	84	5	e4cb79c7aa29e8c99d5a3a209d2f9a03c2ba9bb7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CEP85L SH3KBP1 CD44 IL2RB STAT4	3.00e-05	190	84	5	07ea0578ca0561077557203ae660530f53fc4067
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CEP85L SH3KBP1 CD44 IL2RB STAT4	3.00e-05	190	84	5	5b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CEP85L SH3KBP1 CD44 IL2RB STAT4	3.08e-05	191	84	5	96a7179a845d3daa046ed71fa45c51255f130a7f
ToppCell	COVID-19-kidney-T-cells-1\|kidney / Disease (COVID-19 only), tissue and cell type	CEP85L SH3KBP1 CD44 IL2RB STAT4	3.57e-05	197	84	5	9bb7faf4ef63cca4d06c60e6c05a9616fdb6b98e
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPATA18 DNAH2 KDR ANXA9 SCIN	3.65e-05	198	84	5	6712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPATA18 DNAH2 KDR ANXA9 SCIN	3.74e-05	199	84	5	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPATA18 DNAH2 KDR ANXA9 SCIN	3.74e-05	199	84	5	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TP63 SPATA18 DNAH2 ANXA9 SCIN	3.83e-05	200	84	5	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TP63 SPATA18 DNAH2 ANXA9 SCIN	3.83e-05	200	84	5	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	(01)_IL1RL1+\|World / shred by cell type by condition	PTPN14 TP63 PGAM4 CD44 FAM83A	3.83e-05	200	84	5	501420901bf3ec1b050e0d14596a9f9f3fdfc928
Disease	urinary bladder cancer (is_marker_for)	TP63 CD44 KDR PLK1 VEGFD	1.32e-05	107	83	5	DOID:11054 (is_marker_for)
Disease	Juvenile pauciarticular chronic arthritis	IL2RB STAT4	1.63e-04	7	83	2	C2931171
Disease	Pancreatic Neoplasm	TP63 CD44 KDR ATM	1.86e-04	100	83	4	C0030297
Disease	Malignant neoplasm of pancreas	TP63 CD44 KDR ATM	2.01e-04	102	83	4	C0346647
Disease	Malignant neoplasm of breast	NLRP14 LIPE PTPN14 CEP85L SPATA18 OBSCN DIP2C KDR ATM RAD54L STAT4	2.07e-04	1074	83	11	C0006142
Disease	breast carcinoma (is_marker_for)	KDR ATM PLK1	8.64e-04	66	83	3	DOID:3459 (is_marker_for)
Disease	Low Grade Lymphoma (neoplasm)	BCL6 RAD54L	1.59e-03	21	83	2	C0079747
Disease	Lymphoma, Intermediate-Grade	BCL6 RAD54L	1.59e-03	21	83	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	BCL6 RAD54L	1.59e-03	21	83	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	BCL6 RAD54L	1.59e-03	21	83	2	C0079757
Disease	Lymphoma, Undifferentiated	BCL6 RAD54L	1.59e-03	21	83	2	C0024306
Disease	Reticulosarcoma	BCL6 RAD54L	1.59e-03	21	83	2	C0024302
Disease	Lymphoma, Mixed-Cell	BCL6 RAD54L	1.59e-03	21	83	2	C0024304
Disease	BREAST CANCER	ATM RAD54L	1.59e-03	21	83	2	114480
Disease	Lymphoma, Diffuse	BCL6 RAD54L	1.59e-03	21	83	2	C3714542
Disease	Lymphoma, Non-Hodgkin, Familial	BCL6 RAD54L	1.74e-03	22	83	2	C4721532
Disease	transitional cell carcinoma (is_implicated_in)	TP63 CD44	1.74e-03	22	83	2	DOID:2671 (is_implicated_in)
Disease	Lymphoma, Small Noncleaved-Cell	BCL6 RAD54L	1.74e-03	22	83	2	C0079770
Disease	creatinine measurement	PTPN14 SPEG OBSCN DIP2C ARHGEF18 ACVR2B ANXA9 BIRC6 USP20	1.92e-03	995	83	9	EFO_0004518
Disease	glioblastoma (is_implicated_in)	ADGRB1 KDR	2.07e-03	24	83	2	DOID:3068 (is_implicated_in)
Disease	Left ventricular mass to end-diastolic volume ratio	CEP85L OBSL1	2.25e-03	25	83	2	EFO_0010556
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	CD44 ATM	2.43e-03	26	83	2	C0009405
Disease	Malignant tumor of breast	ATM RAD54L	2.62e-03	27	83	2	cv:C0006142
Disease	Breast neoplasm	ATM RAD54L	2.62e-03	27	83	2	cv:C1458155
Disease	Familial cancer of breast	ATM RAD54L	2.62e-03	27	83	2	cv:C0346153

Protein segments in the cluster

Peptide	Gene	Start	Entry
IEARRVCVTFRELSA	ALKBH4	261	Q9NXW9
IVRRLGVQECILLVT	ARHGEF18	586	Q6ZSZ5
RGCDLLQEVSVTIRR	BIRC6	1291	Q9NR09
ILRREVQDAVKCRVV	ADGRB1	1186	O14514
SITCKARIRRENIVV	FAM78B	6	Q5VT40
CAKTTVERTVRQLER	GTPBP2	321	Q9BX10
VIAELRLRQCADTRV	ABCG8	191	Q9H221
CLRTTEETRRNVTIP	ARL13A	11	Q5H913
CIVRQALEREDSIRT	ANKRD50	516	Q9ULJ7
LVRRAVLRLTVTVQD	ARIH2OS	246	Q8N7S6
SIVNRCLIRRTSDIL	RAD54L	386	Q92698
TAAIISRVQCRIVAL	PPME1	96	Q9Y570
LICQRDTILSERTRD	KASH5	301	Q8N6L0
VATNLVRRLCERETP	ABHD12	251	Q8N2K0
RLTVRERTVAVLSEL	OBSL1	1711	O75147
VITCLICGVLVTTRR	MUC16	14466	Q8WXI7
RQERRLCCVVVLEPV	PASK	221	Q96RG2
LRVVRTTFERCELVR	GRXCR1	146	A8MXD5
LRRCIDKAETVQRII	SPATA18	321	Q8TC71
TVCIRDSQSILVRTR	KIAA2026	1271	Q5HYC2
VELTRELQDSIRRCL	CARMIL3	6	Q8ND23
TCLRRREKVGVIVDV	CLCN7	636	P51798
FCETVKIIIRDQRSV	LRAT	181	O95237
VRRCITRTSQVLVIL	FAM83A	151	Q86UY5
EFDICLTSVQKRVIR	PGAM4	51	Q8N0Y7
QVLIRILISRCETDL	ANXA9	291	O76027
REVISRLRNCIISLV	EXOSC2	231	Q13868
IRCRIQQRNITTVVE	EXOC6	116	Q8TAG9
ETRRSIEVPLNERIC	IL13RA1	81	P78552
QLTRAILRERICSEE	CHCHD3	101	Q9NX63
KVRVEAVGCTRRLVV	OBSCN	1671	Q5VST9
ELRTLCRRLQITTRE	OXR1	671	Q8N573
ERVIDAVRFTLRQTI	TP63	636	Q9H3D4
EDRTEAANRIICTIR	ATM	2596	Q13315
VVSCVVIERVGRRVL	SLC2A11	326	Q9BYW1
IVRGLVRIRCVQEVE	KDM1B	336	Q8NB78
ALILAVCIAVNSRRR	CD44	661	P16070
RVIREVNTTTRACAL	FNDC4	91	Q9H6D8
CVIVIRVLRDLCTRV	ILF3	226	Q12906
VDIVTLRVLCREGVR	IL2RB	101	P14784
DLSRVRTCVVVAEER	DIP2C	1256	Q9Y2E4
RTCVVVAEERPRIAL	DIP2C	1261	Q9Y2E4
VCQLRRDIDELRTTI	CEP85L	776	Q5SZL2
RSRDILTDVVIVVSR	BCL6	26	P41182
VEALVRTRRCVCVAQ	HAS1	196	Q92839
EVLVVLRSISEQCRR	ERMARD	531	Q5T6L9
DQQRRTVRCLRDTVL	ATRIP	711	Q8WXE1
CITIIVGSIRRDRQA	BEAN1	51	Q3B7T3
IVRSLRQDRVAFCVT	DNAH2	3791	Q9P225
QASRVICTRRDLAEV	LRRC4B	66	Q9NT99
TRQAAELCVERIRLV	LIPE	1036	Q05469
VLSIRICRDQVTRRS	PABPC4L	36	P0CB38
EVASVVVQLLSIRRC	IRS4	271	O14654
SSVCRDLDVVRRIIC	NTMT1	181	Q9BV86
ITVRQGDTAILRCVV	LSAMP	41	Q13449
RRNLASITRIVEVDV	SCIN	516	Q9Y6U3
RLQTILRTVEGCIVA	FAM20A	501	Q96MK3
VLEGRLRCTLDQVIR	PTPN14	126	Q15678
ELRTQVRELRSIIET	SH3KBP1	611	Q96B97
VNLSRCRRLIVVLSD	SIGIRR	216	Q6IA17
LVRVCEIQATLREQR	WAC	611	Q9BTA9
RRSCQTALVEILDVI	IARS2	816	Q9NSE4
DLRVTVCQALRTLIT	RRP12	656	Q5JTH9
RVVDLCRNVKERITR	AGPS	536	O00116
AGCVEERVSLIRRSV	ACVR2B	471	Q13705
QRTLSRVELKRLCEI	CLASP1	886	Q7Z460
RLIDRIKTVCEVVNL	NAA35	331	Q5VZE5
RRRGLVIVTELCTEE	SPEG	1666	Q15772
ESLCRVINICERVVR	THAP9	766	Q9H5L6
LRDQGRIVCAERTVL	SPIDR	726	Q14159
VAVVISNCLREERRI	STAT4	101	Q14765
VIRTLRSQEACLEAV	TEDC1	451	Q86SX3
TRVLECPRLIETIVR	RPAP1	581	Q9BWH6
RVARRDICIAFQETL	TAS1R2	226	Q8TE23
SICQVEIEALAKRRR	USP20	781	Q9Y2K6
FVNEVRRCESLERIL	ATP6V0A4	51	Q9HBG4
SCVIIIRILRDLCQR	ZFR	921	Q96KR1
KRHCVVRQLTVLERV	KDR	651	P35968
SIIRRSIQIPEEDRC	VEGFD	201	O43915
LSIVRTNRAEIPIEC	ZP3	126	P21754
TLTAVILVLTRRCRT	ZP3	401	P21754
RLKVLEREVQQCSRV	TRPM4	1171	Q8TD43
KRERLIQSVVECLTF	TTI1	66	O43156
IRSVELQLVRVETCG	VPS26C	206	O14972
VFVVLELCRRRSLLE	PLK1	126	P53350
QSVLSCVRSLRARIV	KEL	506	P23276
RCLRTIRLSVTVVFE	NLRP14	626	Q86W24