Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

PRKD2 DGKZ PARP14 MAST2 CDC42BPB PIK3R4 PARP10 BRAF N4BP2 CSNK2A1 FLAD1 PAK1 PAK3 DGKI PRKCI MERTK PALS2 NME7 CSNK2A3 PIGO

2.74e-0593815120GO:0016772
GeneOntologyMolecularFunctionkinase activity

PRKD2 DGKZ MAST2 CDC42BPB PIK3R4 BRAF N4BP2 CSNK2A1 PAK1 PAK3 DGKI PRKCI MERTK PALS2 NME7 CSNK2A3

2.25e-0476415116GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

PRKD2 DGKZ MAST2 CDC42BPB PIK3R4 BRAF N4BP2 CSNK2A1 PAK1 PAK3 DGKI PRKCI MERTK NME7 CSNK2A3

3.20e-0470915115GO:0016773
GeneOntologyMolecularFunctionToll-like receptor 2 binding

TLR6 TLR1

3.37e-0441512GO:0035663
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK2 DENND4A ARFGEF2 ARHGEF12 ALS2 PLCG1 RAPGEFL1 SOS2

3.82e-042311518GO:0005085
GeneOntologyMolecularFunctionprotein serine kinase activity

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI CSNK2A3

4.52e-0436315110GO:0106310
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK2 RALGAPA1 RGPD2 DENND4A ARFGEF2 ARHGEF12 ALS2 DGKI PLCG1 ARAP2 RAPGEFL1 SOS2

4.85e-0450715112GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK2 RALGAPA1 RGPD2 DENND4A ARFGEF2 ARHGEF12 ALS2 DGKI PLCG1 ARAP2 RAPGEFL1 SOS2

4.85e-0450715112GO:0030695
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK2 RGPD2 NCKAP1 ALS2 CDC42BPB BRAF PAK1 PAK3 DGKI

7.69e-043211519GO:0031267
GeneOntologyCellularComponentcilium

DNHD1 RPGRIP1 DNAH2 ARFGEF2 DZIP1 ADGRV1 PPEF2 CC2D2B PIK3R4 ENO4 TTC8 CATSPER1 PROM2 PKHD1 FHDC1 MERTK NME7 BRWD1

9.55e-0589815218GO:0005929
GeneOntologyCellularComponentendosome

ATG9B TMEM175 ARFGEF2 ALS2 RNASEK VPS16 STEAP2 WDFY4 EHD4 PIK3R4 SNX30 LIPC FIG4 SNX32 PAK3 ASTN2 SDF4 PRKCI SMPD1 AP3D1 DOP1A

1.12e-04116715221GO:0005768
GeneOntologyCellularComponentlamellipodium

NCKAP1 CASP8 DGKZ ALS2 CDC42BPB FAT1 PAK1 PLCG1

2.87e-042301528GO:0030027
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A1 CSNK2A3

3.12e-0441522GO:0005956
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNHD1 RPGRIP1 KIF1B DNAH2 ARFGEF2 PIK3R4 NME7 AP3D1 BRWD1

5.34e-043171529GO:0032838
GeneOntologyCellularComponentaxoneme

DNHD1 RPGRIP1 DNAH2 ARFGEF2 PIK3R4 NME7 BRWD1

8.13e-042071527GO:0005930
GeneOntologyCellularComponentciliary plasm

DNHD1 RPGRIP1 DNAH2 ARFGEF2 PIK3R4 NME7 BRWD1

8.36e-042081527GO:0097014
GeneOntologyCellularComponent9+0 non-motile cilium

RPGRIP1 ADGRV1 PPEF2 TTC8 PKHD1 MERTK

8.98e-041531526GO:0097731
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

MPP2 DGKZ DGKI PRKCI PLCG1 ADGRL3

9.61e-041551526GO:0098685
GeneOntologyCellularComponentcell leading edge

MPP2 NCKAP1 CASP8 DGKZ ALS2 ADGRV1 CDC42BPB FAT1 PAK1 PRKCI PLCG1

1.10e-0350015211GO:0031252
DomainVWA

COL12A1 MATN2 COL6A5 COL22A1 VIT CLCA2 ITIH6

3.42e-07561527PF00092
Domain-

COL12A1 MATN2 COL6A5 COL22A1 VIT CLCA2 ITIH6

2.35e-067415273.40.50.410
DomainVWFA

COL12A1 MATN2 COL6A5 COL22A1 VIT CLCA2 ITIH6

4.70e-06821527PS50234
DomainVWA

COL12A1 MATN2 COL6A5 COL22A1 VIT CLCA2 ITIH6

5.52e-06841527SM00327
DomainC1_1

PRKD2 DGKZ CDC42BPB BRAF DGKI PRKCI

6.78e-06571526PF00130
DomainZF_DAG_PE_1

PRKD2 DGKZ CDC42BPB BRAF DGKI PRKCI

1.34e-05641526PS00479
DomainZF_DAG_PE_2

PRKD2 DGKZ CDC42BPB BRAF DGKI PRKCI

1.34e-05641526PS50081
DomainC1

PRKD2 DGKZ CDC42BPB BRAF DGKI PRKCI

1.46e-05651526SM00109
DomainPE/DAG-bd

PRKD2 DGKZ CDC42BPB BRAF DGKI PRKCI

1.60e-05661526IPR002219
DomainVWF_A

COL12A1 MATN2 COL6A5 COL22A1 VIT CLCA2 ITIH6

1.64e-05991527IPR002035
DomainDAG/PE-bd

PRKD2 CDC42BPB BRAF PRKCI

2.27e-05211524IPR020454
Domain-

CDC42BPB PAK1 PAK3

1.10e-041215233.90.810.10
DomainETS_PEA3_N

ETV1 ETV4

1.96e-0431522IPR006715
DomainETS_PEA3_N

ETV1 ETV4

1.96e-0431522PF04621
DomainPBD

CDC42BPB PAK1 PAK3

2.74e-04161523SM00285
DomainPBD

CDC42BPB PAK1 PAK3

3.30e-04171523PF00786
DomainWD40/YVTN_repeat-like_dom

PLXNA3 WDR36 PLXNB2 WDFY4 PIK3R4 STRN SF3B3 CSTF1 ANAPC4 BRWD1

4.27e-0433515210IPR015943
DomainARM-type_fold

DOCK2 RALGAPA1 ARFGEF2 MEI1 WDFY4 SDAD1 RYR3 PIK3R4 ASPM AP3D1

4.68e-0433915210IPR016024
DomainCRIB

CDC42BPB PAK1 PAK3

5.44e-04201523PS50108
DomainCRIB_dom

CDC42BPB PAK1 PAK3

6.31e-04211523IPR000095
DomainLEM

TMPO EMD

6.47e-0451522SM00540
DomainToll-like_receptor

TLR6 TLR1

6.47e-0451522IPR017241
DomainSer/Thr_kinase_AS

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI CSNK2A3

6.99e-0435715210IPR008271
DomainS_TKc

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI CSNK2A3

7.29e-0435915210SM00220
DomainPROTEIN_KINASE_ST

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI CSNK2A3

7.77e-0436215210PS00108
DomainPAK_BD

PAK1 PAK3

9.66e-0461522IPR033923
DomainPkinase

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI CSNK2A3

1.14e-0338115210PF00069
DomainIPT

PLXNA3 PLXNB2 PKHD1

1.34e-03271523SM00429
DomainLEM/LEM-like_dom

TMPO EMD

1.35e-0371522IPR011015
DomainLEM_dom

TMPO EMD

1.35e-0371522IPR003887
DomainLEM

TMPO EMD

1.35e-0371522PF03020
DomainLEM

TMPO EMD

1.35e-0371522PS50954
Domain-

TMPO EMD

1.35e-03715221.10.720.40
DomainPROTEIN_KINASE_ATP

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI MERTK CSNK2A3

1.36e-0345915211PS00107
Domain-

PLXNA3 WDR36 PLXNB2 WDFY4 PIK3R4 STRN CSTF1 ANAPC4 BRWD1

1.65e-0333315292.130.10.10
DomainCalx_beta

FRAS1 ADGRV1

1.78e-0381522SM00237
DomainTIG

PLXNA3 PLXNB2 PKHD1

2.01e-03311523PF01833
DomainPH

PRKD2 KIF1B ARHGEF12 ALS2 CDC42BPB PLCG1 ARAP2 SOS2

2.02e-032781528SM00233
DomainPH_DOMAIN

PRKD2 KIF1B ARHGEF12 ALS2 CDC42BPB PLCG1 ARAP2 SOS2

2.06e-032791528PS50003
DomainPH_domain

PRKD2 KIF1B ARHGEF12 ALS2 CDC42BPB PLCG1 ARAP2 SOS2

2.11e-032801528IPR001849
DomainIPT

PLXNA3 PLXNB2 PKHD1

2.20e-03321523IPR002909
DomainPlexin_repeat

PLXNA3 PLXNB2 PLXDC2

2.20e-03321523IPR002165
DomainPSI

PLXNA3 PLXNB2 PLXDC2

2.20e-03321523PF01437
DomainProt_kinase_dom

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI MERTK CSNK2A3

2.23e-0348915211IPR000719
DomainWD40_repeat_CS

WDR36 WDFY4 PIK3R4 STRN CSTF1 BRWD1

2.26e-031641526IPR019775
DomainCalx_beta

FRAS1 ADGRV1

2.28e-0391522IPR003644
DomainPlexin_cytopl

PLXNA3 PLXNB2

2.28e-0391522PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNB2

2.28e-0391522IPR013548
DomainPlexin

PLXNA3 PLXNB2

2.28e-0391522IPR031148
DomainCalx-beta

FRAS1 ADGRV1

2.28e-0391522PF03160
DomainPROTEIN_KINASE_DOM

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI MERTK CSNK2A3

2.38e-0349315211PS50011
DomainPH_dom-like

PRKD2 RGPD2 KIF1B ARHGEF12 ALS2 WDFY4 CDC42BPB PLCG1 ARAP2 SOS2

2.60e-0342615210IPR011993
DomainL27_C

MPP2 PALS2

2.84e-03101522IPR014775
DomainDAGK_acc

DGKZ DGKI

2.84e-03101522PF00609
DomainDiacylglycerol_kin_accessory

DGKZ DGKI

2.84e-03101522IPR000756
DomainL27

MPP2 PALS2

2.84e-03101522PF02828
DomainDAGKa

DGKZ DGKI

2.84e-03101522SM00045
DomainWD40_repeat_dom

WDR36 WDFY4 PIK3R4 STRN SF3B3 CSTF1 ANAPC4 BRWD1

3.03e-032971528IPR017986
DomainGDS_CDC24_CS

ARHGEF12 ALS2 SOS2

3.90e-03391523IPR001331
DomainProtein_kinase_ATP_BS

PRKD2 CDC42BPB BRAF CSNK2A1 PAK1 PAK3 PRKCI MERTK CSNK2A3

3.91e-033791529IPR017441
Domain-

PRKD2 RGPD2 KIF1B ARHGEF12 ALS2 CDC42BPB PLCG1 ARAP2 SOS2

4.79e-0339115292.30.29.30
DomainPkinase_C

MAST2 CDC42BPB PRKCI

4.81e-03421523PF00433
DomainL27

MPP2 PALS2

4.84e-03131522SM00569
DomainL27

MPP2 PALS2

4.84e-03131522PS51022
DomainL27_dom

MPP2 PALS2

4.84e-03131522IPR004172
DomainKinase-like_dom

PRKD2 MAST2 CDC42BPB PIK3R4 BRAF CSNK2A1 PAK1 PAK3 PRKCI MERTK CSNK2A3

4.86e-0354215211IPR011009
DomainPSI

PLXNA3 PLXNB2 PLXDC2

5.48e-03441523IPR016201
DomainDynein_HC_stalk

DNHD1 DNAH2

5.62e-03141522IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH2

5.62e-03141522IPR013602
DomainDHC_N2

DNHD1 DNAH2

5.62e-03141522PF08393
DomainMT

DNHD1 DNAH2

5.62e-03141522PF12777
DomainDAGKc

DGKZ DGKI

5.62e-03141522SM00046
DomainPSI

PLXNA3 PLXNB2 PLXDC2

6.21e-03461523SM00423
DomainDHC_fam

DNHD1 DNAH2

6.44e-03151522IPR026983
DomainDiacylglycerol_kinase_cat_dom

DGKZ DGKI

6.44e-03151522IPR001206
DomainDAGK

DGKZ DGKI

6.44e-03151522PS50146
DomainDynein_heavy

DNHD1 DNAH2

6.44e-03151522PF03028
DomainDAGK_cat

DGKZ DGKI

6.44e-03151522PF00781
DomainDynein_heavy_dom

DNHD1 DNAH2

6.44e-03151522IPR004273
DomainARM-like

DOCK2 ARFGEF2 MEI1 WDFY4 PIK3R4 ASPM AP3D1

6.69e-032701527IPR011989
DomainGuanylate_kinase_CS

MPP2 PALS2

7.33e-03161522IPR020590
Domain-

PLXNA3 PLXNB2

7.33e-031615221.10.506.10
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

STRN BRAF PAK1 PAK3 PLCG1 SOS2

9.50e-06591186M39750
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK2 NCKAP1 ALS2 PAK1 PAK3 TMPO EMD ARAP2 SOS2

2.38e-051841189M41809
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MPP2 RGPD2 NCKAP1 HCN3 ARHGEF12 DGKZ CDC42BPB ADAM22 STRN KCNA1 ZKSCAN1 KCNJ1 N4BP2 CSNK2A1 PAK1 PAK3 DGKI PRKCI RPA1 CEP170B

1.25e-089631552028671696
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 PRKD2 DENND4A TBRG4 WDR36 NCKAP1 BIRC3 CMYA5 THOC2 MAST2 SDAD1 EHD4 PIK3R4 SF3B3 CLCA2 CSNK2A1 CSTF1 TMPO PRKCI PLCG1 EMD GALNT5 RPA1

9.56e-0814251552330948266
Pubmed

Cloning, central nervous system expression and chromosomal mapping of the mouse PAK-1 and PAK-3 genes.

GRPR TYR PAK1 PAK3

1.22e-0711155410352232
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

MPP2 PLXNA3 PRKD2 CASP8 CCDC90B DGKZ MAST2 PLXNB2 TTR DSN1 JMJD1C SF3B3 FLAD1 PAK1 SDF4 PRKCI SMPD1 EMD STX11 RPA1

1.54e-0711241552021900206
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NCKAP1 KCMF1 MEI1 SDAD1 RYR3 PIK3R4 CSNK2A1 FGA TMPO GALNT5 CSNK2A3 AP3D1 ANAPC4

4.01e-074971551336774506
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DENND4A TBRG4 NCKAP1 KIF1B SMPD4 ALS2 RB1CC1 CMYA5 MAST2 CDC42BPB JMJD1C SDAD1 EHD4 PIK3R4 STRN SF3B3 BRAF CSNK2A1 ASPM MOV10

1.23e-0612841552017353931
Pubmed

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation.

BRAF PAK1 PAK3

1.72e-066155310205168
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

DENND4A NCKAP1 KIF1B ALS2 PIK3R4 SF3B3 BRAF CSNK2A1 PAK1

2.36e-06255155915324660
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

MPP2 TBRG4 COL12A1 HCN3 FKBP9 ITGA6 COL22A1 MAST2 STRN FAT1 ZKSCAN1 CSTF1 DGKI PALS2

2.80e-066891551436543142
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RALGAPA1 KIF1B ETV1 RTN4RL1 ADGRV1 STEAP2 CDC42BPB JMJD1C TTC8 SNX30 PARP10 PLXDC2 PROM2 PAK3 ASTN2 PRKCI PLCG1 PALS2 CEP170B DOP1A SOS2

3.12e-0614891552128611215
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

RALGAPA1 DENND4A NCKAP1 KIF1B THOC2 MAST2 STRN BRAF PRKCI NME7 CEP170B

5.64e-064461551124255178
Pubmed

FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

CASP8 TLR6 TLR1

7.15e-069155320554749
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 FRAS1 COL12A1 MATN2 MARCHF6 FKBP9 ARFGEF2 ITGA6 PLXNB2 ADAM22 FAT1 SNX32 TMPO SDF4 SMPD1 TWSG1 PIGO DSE

7.40e-0612011551835696571
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

TBRG4 MIS18BP1 WDR36 NCKAP1 ORC3 ITGA6 SMPD4 THOC2 PLXNB2 JMJD1C SDAD1 GSE1 ZKSCAN1 TMPO TWSG1 EMD AP3D1 ANAPC4

7.57e-0612031551829180619
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 DENND4A NCKAP1 KIF1B ALS2 DZIP1 DPP8 MAST2 PIK3R4 BRAF N4BP2 PRKCI CEP170B ARAP2 DOP1A

7.80e-068611551536931259
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 COL12A1 MATN2 COL6A5 PLXNB2 PLXDC2 FGA

1.06e-05167155722159717
Pubmed

Genomic analysis of mouse retinal development.

MPP2 RPGRIP1 CGA RNASEK COL22A1 MAST2 TTR DSN1 PIK3R4 TIA1 CSNK2A1 PAK3 TMPO PRKCI TWSG1 MERTK

1.19e-0510061551615226823
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 WDFY4 CDC42BPB JMJD1C FIG4 N4BP2 TLR1 ASTN2 FHDC1 MOV10 DOP1A

1.44e-054931551115368895
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

PRKD2 NCKAP1 CCDC90B RB1CC1 SDAD1 PIK3R4 BRAF CSNK2A1 PAK3 PRKCI DDX43 PLCG1 MERTK CSNK2A3 ANAPC4

1.50e-059101551536736316
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

KCMF1 ETV1 ITGA6 PLXNB2 SDAD1 FGA TMPO EMD AP3D1 CEP170B MOV10

1.73e-055031551136217030
Pubmed

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

DOCK2 CASP8 CDC42BPB ENTPD4 EHD4 CSTF1 PLCG1 EMD PALS2

1.74e-05327155915592455
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

RALGAPA1 DENND4A ARFGEF2 ITGA6 VPS16 ADAM22 PIK3R4 SNX30 FIG4 TMPO EMD

1.76e-055041551134432599
Pubmed

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

ARHGEF12 PLXNB2 PAK1

1.85e-0512155312123608
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

WDR36 MATN2 RGCC KCMF1 ADAM22 CATSPER1 VNN1 DDX43 ANAPC4

1.91e-05331155919490893
Pubmed

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

TLR6 TLR1

1.97e-052155222315281
Pubmed

Structural characterization of the LEM motif common to three human inner nuclear membrane proteins.

TMPO EMD

1.97e-052155211435115
Pubmed

MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases.

ETV1 BRAF

1.97e-052155225073704
Pubmed

[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].

TLR6 TLR1

1.97e-052155226470427
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A1 CSNK2A3

1.97e-052155214646071
Pubmed

Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.

TLR6 TLR1

1.97e-052155221852947
Pubmed

p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties.

PAK1 PAK3

1.97e-052155221115725
Pubmed

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

PARP14 PARP10

1.97e-052155218851833
Pubmed

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.

TLR6 TLR1

1.97e-052155211123271
Pubmed

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

TLR6 TLR1

1.97e-052155229175392
Pubmed

Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts.

ETV1 ETV4

1.97e-052155225595908
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A1 CSNK2A3

1.97e-052155212860116
Pubmed

The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.

TLR6 TLR1

1.97e-052155228474755
Pubmed

The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.

PAK1 PAK3

1.97e-052155222815483
Pubmed

The LEM domain proteins emerin and LAP2alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections.

TMPO EMD

1.97e-052155218400857
Pubmed

Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells.

PAK1 PLCG1

1.97e-052155212085993
Pubmed

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

TLR6 TLR1

1.97e-052155218036178
Pubmed

Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.

CASP8 FAT1

1.97e-052155227693639
Pubmed

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

TLR6 TLR1

1.97e-052155224445834
Pubmed

Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.

PAK1 PAK3

1.97e-052155223622267
Pubmed

Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis.

PAK1 PAK3

1.97e-052155230858169
Pubmed

Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).

TLR6 TLR1

1.97e-052155224984237
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A1 CSNK2A3

1.97e-05215521577469
Pubmed

A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.

CASP8 FAT1

1.97e-052155224442637
Pubmed

SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.

TLR6 TLR1

1.97e-052155225261617
Pubmed

Expression of p21-activated kinases 1 and 3 is altered in the brain of subjects with depression.

PAK1 PAK3

1.97e-052155227474226
Pubmed

Assessment of Intracellular Auto-Modification Levels of ARTD10 Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8.

PARP14 PARP10

1.97e-052155230097860
Pubmed

Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma.

BRAF CSNK2A1

1.97e-052155227226552
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A1 CSNK2A3

1.97e-05215522752008
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A1 CSNK2A3

1.97e-05215528420794
Pubmed

Protein kinase CK2 phosphorylates and activates p21-activated kinase 1.

CSNK2A1 PAK1

1.97e-052155223885116
Pubmed

A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.

TLR6 TLR1

1.97e-052155222778390
Pubmed

Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes.

DGKZ TYR

1.97e-052155222895365
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MPP2 RALGAPA1 NCKAP1 KIF1B FKBP9 ARFGEF2 ARHGEF12 DGKZ CDC42BPB ADAM22 PIK3R4 STRN KCNA1 SF3B3 CSNK2A1 FGA TMPO AP3D1 CEP170B

2.21e-0514311551937142655
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

RALGAPA1 NCKAP1 DGKZ VPS16 ADGRV1 CDC42BPB ADAM22 CSNK2A1 AP3D1 CEP170B

2.51e-054301551032581705
Pubmed

PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.

CDC42BPB PAK1 PAK3

3.05e-0514155318586681
Pubmed

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.

IYD LIPC ADGRL3

3.80e-0515155319043545
Pubmed

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.

DENND4A KIF1B MAST2 BRAF PRKCI

4.54e-0587155517979178
Pubmed

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

CSNK2A1 CSNK2A3

5.90e-053155215684395
Pubmed

Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.

TLR6 TLR1

5.90e-053155216081826
Pubmed

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.

PAK1 PAK3

5.90e-053155215182717
Pubmed

ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.

ETV1 ETV4

5.90e-053155222425584
Pubmed

PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro.

ETV1 ETV4

5.90e-053155212871699
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A1 CSNK2A3

5.90e-05315522174700
Pubmed

Compartmentalization of TNF-receptor 1 signaling: TNF-R1-associated caspase-8 mediates activation of acid sphingomyelinase in late endosomes.

CASP8 SMPD1

5.90e-053155221153367
Pubmed

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.

TLR6 TLR1

5.90e-053155218752252
Pubmed

Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.

ETV1 ETV4

5.90e-053155225203299
Pubmed

Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs.

TLR6 TLR1

5.90e-053155215731092
Pubmed

Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.

ETV1 ETV4

5.90e-053155228859074
Pubmed

IFNs activate toll-like receptor gene expression in viral infections.

TLR6 TLR1

5.90e-053155211607792
Pubmed

Ureaplasma parvum lipoproteins, including MB antigen, activate NF-{kappa}B through TLR1, TLR2 and TLR6.

TLR6 TLR1

5.90e-053155218451040
Pubmed

TLR1- and TLR6-independent recognition of bacterial lipopeptides.

TLR6 TLR1

5.90e-053155216455646
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A1 CSNK2A3

5.90e-05315521766873
Pubmed

A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.

TLR6 TLR1

5.90e-053155216177110
Pubmed

Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis.

TLR6 TLR1

5.90e-053155222150367
Pubmed

ETS transcription factor ER81 is required for the Pacinian corpuscle development.

ETV1 ETV4

5.90e-053155216493690
Pubmed

Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

TLR6 TLR1

5.90e-053155223626692
Pubmed

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.

TLR6 TLR1

5.90e-053155215812078
Pubmed

Crystallization and preliminary characterization of crystals of human protein kinase CK2.

CSNK2A1 CSNK2A3

5.90e-053155211092945
Pubmed

Epistatic effect of TLR-1, -6 and -10 polymorphisms on organic dust-mediated cytokine response.

TLR6 TLR1

5.90e-053155228123183
Pubmed

Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-β-induced smooth muscle cell differentiation of neural crest cells.

RGCC ETV4

5.90e-053155221613609
Pubmed

Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

CSNK2A1 CSNK2A3

5.90e-053155212102635
Pubmed

Toll-like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette-Guérin osteitis following newborn vaccination.

TLR6 TLR1

5.90e-053155225605403
Pubmed

Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

TLR6 TLR1

5.90e-053155214966134
Pubmed

Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.

TLR6 TLR1

5.90e-053155217932345
Pubmed

Toll-like receptor 2 subfamily genotypes are not associated with severity of bronchiolitis or postbronchiolitis wheezing in infants.

TLR6 TLR1

5.90e-053155224112285
Pubmed

Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.

ARHGEF12 PLXNB2

5.90e-053155226627240
Pubmed

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.

TLR6 TLR1

5.90e-053155212077222
Pubmed

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338.

PAK1 PAK3

5.90e-05315529823899
Pubmed

Caspase-dependent and -independent activation of acid sphingomyelinase signaling.

CASP8 SMPD1

5.90e-053155215849201
Pubmed

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

TLR6 TLR1

5.90e-053155218056480
Pubmed

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.

PAK1 PAK3

5.90e-053155229860311
Pubmed

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

TLR6 TLR1

5.90e-053155221998742
Pubmed

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

CSNK2A1 CSNK2A3

5.90e-053155220625391
Pubmed

Soluble Toll-like receptor 1 family members in the amniotic fluid of women with preterm prelabor rupture of the membranes.

TLR6 TLR1

5.90e-053155222280448
Pubmed

PEA3/ETV4-related transcription factors coupled with active ERK signalling are associated with poor prognosis in gastric adenocarcinoma.

ETV1 ETV4

5.90e-053155221673681
Cytoband4p14

TLR6 N4BP2 TLR1 ARAP2

1.27e-054215544p14
CytobandEnsembl 112 genes in cytogenetic band chr4p14

TLR6 N4BP2 TLR1 ARAP2

8.12e-05671554chr4p14
Cytoband6q12-q13

COL12A1 DDX43

1.13e-04515526q12-q13
GeneFamilyLEM domain containing

TMPO EMD

6.50e-04710221087
GeneFamilyAutophagy related

ATG9B RB1CC1 SNX30

8.41e-043310231022
GeneFamilyPlexins

PLXNA3 PLXNB2

1.11e-0391022683
GeneFamilyCD molecules|Toll like receptors

TLR6 TLR1

1.38e-03101022948
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKZ DGKI

1.38e-031010221178
GeneFamilyEF-hand domain containing

FKBP9 PPEF2 RYR3 EHD4 SDF4 PLCG1

1.51e-032191026863
GeneFamilySorting nexins|PX-BAR domain containing

SNX30 SNX32

2.00e-031210221290
GeneFamilyCollagens

COL12A1 COL6A5 COL22A1

2.22e-03461023490
GeneFamilyWD repeat domain containing

WDR36 WDFY4 PIK3R4 STRN CSTF1 BRWD1

3.69e-032621026362
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP14 PARP10

4.06e-03171022684
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 ALS2 SOS2

6.17e-03661023722
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGV PIGO

6.17e-03211022680
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PRKD2 KIF1B PLCG1 ARAP2 SOS2

6.24e-032061025682
CoexpressionGSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN

CASP8 COL6A5 PARP14 WDFY4 ENTPD4 PIK3R4 SDF4 SMPD1 PLCG1

2.99e-062001549M5995
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCKAP1 MARCHF6 ITGA6 CASP8 RB1CC1 THOC2 MAST2 PIK3R4 FAT1 GSE1 TIA1 CSNK2A1 PRKCI PALS2 TRAM2 ARAP2 SOS2

1.23e-0585615417M4500
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_1000

ITGA6 RTN4RL1 BIRC3 VNN1 PAK3

4.33e-05541535gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_top-relative-expression-ranked_1000

COL12A1 MATN2 ARFGEF2 RTN4RL1 VIT PARP14 TTR RYR3 EHD4 STRN CLCA2 PROM2 PKHD1 GALNT5 STX11 ARAP2 RAPGEFL1

4.47e-0577415317gudmap_developingLowerUrinaryTract_P1_ureter_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_top-relative-expression-ranked_1000

FRAS1 KIF1B ETV1 ARFGEF2 PARP14 TTR EHD4 STRN KRT75 CLCA2 FIG4 PROM2 PKHD1 PAK1 PRKCI ARAP2 RAPGEFL1

4.91e-0578015317gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL12A1 COL6A5 COL22A1 ADGRV1 RYR3 TYR PKHD1

9.48e-081601558c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL12A1 COL6A5 COL22A1 ADGRV1 RYR3 TYR PKHD1

9.48e-08160155825c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL12A1 COL22A1 ADGRV1 RYR3 FAT1 PKHD1 ADGRL3

2.77e-0718415582cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL12A1 COL22A1 ADGRV1 RYR3 FAT1 PKHD1 ADGRL3

2.77e-071841558ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL12A1 COL22A1 ADGRV1 RYR3 FAT1 PKHD1 ADGRL3

2.77e-0718415582b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RALGAPA1 DENND4A MARCHF6 RB1CC1 PARP14 JMJD1C BRAF ARAP2

3.26e-071881558ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCKAP1 FKBP9 ARHGEF12 RB1CC1 JMJD1C PLXDC2 CSNK2A1 TWSG1

4.65e-071971558e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 FKBP9 ARHGEF12 RB1CC1 JMJD1C PLXDC2 CSNK2A1 TWSG1

4.65e-0719715580353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 MATN2 ARHGEF12 ITGA6 RB1CC1 SF3B3 PRKCI TWSG1

5.02e-0719915588d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 RGPD2 BIRC3 MEI1 WDFY4 MERTK TRAM2 STX11

5.02e-0719915581bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HCN3 COL22A1 PPEF2 RYR3 DGKI EMD STX11

5.31e-07137155725b5370b63644351efddb8749ef174beca0581cd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 CGA PPEF2 WDFY4 VNN1 TLR1 STX11

2.74e-061751557e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCellcellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK2 TLR6 CATSPER1 PLXDC2 TLR1 PAK1 DSE

3.68e-0618315579840706f972387241bf1d4ba8af25efc3214a91b
ToppCellcellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK2 TLR6 CATSPER1 PLXDC2 TLR1 PAK1 DSE

3.68e-061831557409cb52cf4c967e52bf75a6680bcbe87f638c75d
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ATG9B ORC3 RGCC ITGA6 PCED1B FAM153B N4BP2

4.39e-061881557b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ETV1 ETV4 DZIP1 ADGRV1 RYR3 ASTN2 MERTK

4.55e-061891557e059be2965cca70ff5576df055d0af1775b76e00
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ITGA6 BIRC3 PARP14 STEAP2 PLXNB2 TMPO HS3ST1

5.04e-0619215574e689bca7a242f8482e25f273656e2caba8821c0
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ITGA6 BIRC3 MEI1 DGKI MERTK TRAM2

5.22e-0619315575c5543e7c83ecea44d23521246592c0301044173
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

RALGAPA1 C2orf69 KIF1B ADGRV1 THOC2 STRN N4BP2

5.22e-061931557abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 ARHGEF12 ITGA6 EHD4 PLCG1 ADGRL3 ARAP2

5.40e-061941557f159ef8541d75a4e98468947f231bb463bec922c
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCKAP1 STEAP2 PLXNB2 FAT1 PROM2 GALNT5 HS3ST1

5.77e-06196155770384c1da9baed843f414cfd1403ddd586a2db07
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ITGA6 BIRC3 MEI1 WDFY4 DGKI TRAM2

5.77e-061961557fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MATN2 ETV1 ETV4 VIT ABCA10 PAK3 ADGRL3

6.37e-06199155745c3b853900d8c3d5965117d904e3714100138bc
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 NCKAP1 ARHGEF12 ITGA6 PARP14 ENTPD4 ADGRL3

6.59e-06200155772ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 NCKAP1 ARHGEF12 ITGA6 PARP14 ENTPD4 ADGRL3

6.59e-0620015575c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MATN2 ETV1 ETV4 VIT ABCA10 PAK3 ADGRL3

6.59e-06200155729054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL12A1 SGCA DSN1 ADAMTS7 STX11 HS3ST1

2.56e-05166155649103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 C2orf69 WDR36 KCMF1 PPEF2 CALHM2

2.73e-0516815562e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNHD1 RGCC TLR6 PLXNB2 TTC8 PLXDC2

2.73e-0516815568c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

TLR6 PLXDC2 VNN1 TLR1 MERTK HS3ST1

2.83e-0516915562c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL22A1 ADGRV1 RYR3 PKHD1 DGKI

2.83e-05169155612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPEF2 WDFY4 SDAD1 ENO4 PAK1 PALS2

2.92e-051701556bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

NCKAP1 ITGA6 PROM2 PUS10 PRKCI GALNT5

3.02e-051711556adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL12A1 MIS18BP1 HCN3 ADAMTS7 ASPM TMPO

3.12e-051721556c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

MATN2 BIRC3 WDFY4 ABCA10 SNX32 FHDC1

3.22e-0517315563a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

DOCK2 COL22A1 TLR6 PLXDC2 TLR1 DSE

3.90e-051791556cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CA9 ETV4 ADGRV1 STEAP2 TTR SNX32

3.90e-0517915568ce5000088b727783a0619baa16a2cd036d21f54
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 COL12A1 ADGRV1 PKHD1 ASTN2 PALS2

4.15e-0518115569d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 COL12A1 ADGRV1 PKHD1 ASTN2 PALS2

4.28e-051821556eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellIPF-Myeloid-Mast|IPF / Disease state, Lineage and Cell class

DENND4A BIRC3 ALS2 GSE1 ADAMTS7 PAK1

4.55e-051841556c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DENND4A PKHD1 DGKI ASTN2 PALS2

4.83e-051861556f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DZIP1 ADGRV1 PKHD1 ASTN2 PALS2

4.97e-051871556c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STRN LIPC PKHD1 ASTN2 PRKCI ADGRL3

5.12e-05188155663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

CA9 NCKAP1 STEAP2 FAT1 FAM153B PALS2

5.28e-05189155679bb2593ad5d17f94b17972884241f03a0f43770
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DZIP1 ADGRV1 PKHD1 ASTN2 PALS2

5.43e-0519015561cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellCOPD-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

NCKAP1 BIRC3 RYR3 GSE1 ADAMTS7 PAK1

5.43e-051901556379dbac19110b76079a7a53209569e060a852acb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DZIP1 ADGRV1 PKHD1 ASTN2 PALS2

5.43e-05190155659bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 MIS18BP1 RGCC ASPM TMPO FHDC1

5.59e-05191155608be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RGPD2 DENND4A ARFGEF2 SMPD4 RB1CC1 JMJD1C

5.59e-0519115561ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A BIRC3 PARP14 WDFY4 BRAF PALS2

5.76e-051921556446c61c0d6ba89c619efe87ee495951299953981
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 ARHGEF12 ITGA6 EHD4 ADGRL3 ARAP2

5.76e-0519215564bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RGCC DGKZ RYR3 EHD4 PCED1B GSE1

5.76e-051921556c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRAS1 PPEF2 TYR RNF113B PKHD1 ITIH6

5.93e-051931556315840bc48899f3a36d57b19197509de19716e3d
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

NCKAP1 RTN4RL1 COL22A1 STEAP2 ADAMTS7 GALNT5

5.93e-0519315568f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A BIRC3 PARP14 WDFY4 BRAF PALS2

5.93e-051931556bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

DOCK2 MIS18BP1 WDFY4 PCED1B PLXDC2 FIG4

5.93e-051931556cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 KIF1B PLXNB2 TIA1 AP3D1 CEP170B

5.93e-051931556471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

CA9 FRAS1 ETV4 BIRC3 PKHD1 PAK3

5.93e-0519315569152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RGCC DGKZ RYR3 EHD4 PCED1B GSE1

5.93e-05193155652e918884877b6659cdca0496390e440f73694a9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ITGA6 CMYA5 FAT1 PKHD1 ASTN2

6.10e-0519415567002937e8903e037332a215d00fbc7c7843b33f2
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 SGCA RGCC ETV1 COL6A5 PLXDC2

6.10e-051941556d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 SGCA RGCC ETV1 COL6A5 PLXDC2

6.10e-051941556e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SGCA MATN2 DZIP1 FAT1 PAK3

6.27e-051951556ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCelldistal-Epithelial-Differentiating_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CA9 FRAS1 CMYA5 CLCA2 PROM2 RAPGEFL1

6.27e-0519515563fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ITGA6 MEI1 DGKI MERTK TRAM2

6.27e-0519515560b0615553b9a1b60d666d074ce4260919e2d5642
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ITGA6 MEI1 DGKI MERTK TRAM2

6.27e-051951556bb30ac112f8c42d113fa83a9b662e40c0685bb1e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 CASP8 WDFY4 EHD4 PCED1B MERTK

6.45e-05196155689a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 FKBP9 BIRC3 VIT PLXDC2 DSE

6.45e-05196155661bee32ca299219f31a30b57124e44e85b798e9f
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 FKBP9 ETV4 COL22A1 VIT PLXDC2

6.45e-051961556fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 CASP8 WDFY4 EHD4 PCED1B MERTK

6.45e-05196155691a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MATN2 RYR3 PCED1B FAT1 PLXDC2 PAK3

6.64e-051971556f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCKAP1 DSN1 ADAM22 ASPM DGKI CEP170B

6.64e-05197155670704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell(5)_Fibroblasts-(5)_Fibroblast-G|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 RGCC ETV1 COL6A5 MEI1 PLXDC2

6.64e-051971556a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 ARHGEF12 RB1CC1 PRKCI TWSG1 ARAP2

6.83e-0519815562f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

FRAS1 SGCA RGCC ETV1 COL6A5 PLXDC2

6.83e-051981556e0e47cf65774191981840b22905b2094b95abe0f
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ITGA6 MEI1 DGKI MERTK TRAM2

6.83e-051981556567fcf882c8612356946240843525b786f3c8dbe
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 WDFY4 VNN1 KCNJ1 TLR1 ASPM

6.83e-051981556732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 ARHGEF12 RB1CC1 PRKCI TWSG1 ARAP2

6.83e-051981556f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 TLR6 PARP14 WDFY4 TLR1 MERTK

7.02e-051991556f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SGCA MATN2 DZIP1 ADAM22 FAT1 PAK3

7.02e-051991556e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 FKBP9 ETV4 COL22A1 VIT PLXDC2

7.02e-051991556edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 BIRC3 MEI1 WDFY4 MERTK TRAM2

7.02e-0519915562f60682f1b82918a65e8851e99c9e3398845b62f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 TLR6 PARP14 WDFY4 TLR1 MERTK

7.02e-0519915565ceeed92f831d068ff4bb3994f420002338330e7
ToppCelldistal-Epithelial-Differentiating_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CA9 CGA ETV4 CLCA2 GALNT5 RAPGEFL1

7.02e-051991556286d52f25120293620bdbfd62b832f08e118adf6
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 BIRC3 MEI1 WDFY4 MERTK TRAM2

7.02e-05199155658242d78517c05fa367a7c6edac57ef79107453c
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COL12A1 MATN2 COL6A5 ABCA10 PLXDC2 ADGRL3

7.02e-05199155656d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL12A1 ARHGEF12 ITGA6 DGKZ ADGRL3 BRWD1

7.22e-052001556dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PRKD2 COL12A1 ARHGEF12 ITGA6 PARP14 ENTPD4

7.22e-0520015566f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellproximal-3-Epithelial-Proximal_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CMYA5 CLCA2 PROM2 KCNJ1 HS3ST1 RAPGEFL1

7.22e-0520015563a0c84f9a551fc2581ec3693481eada297d83f7b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SGCA DZIP1 ADAM22 CALHM2 FAT1 PAK3

7.22e-052001556f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MATN2 ETV4 VIT STEAP2 ALKBH8 PAK3

7.22e-05200155636de49593cf6ff1c9229fcceb150c1d68658a360
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CMYA5 ZKSCAN1 PLXDC2 PAK3 PALS2 ITIH6

7.22e-052001556b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellproximal-Epithelial-Proximal_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CMYA5 CLCA2 PROM2 KCNJ1 HS3ST1 RAPGEFL1

7.22e-052001556de9aec87c86ad0a1bd5e0737c2aae0ec6f269bca
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 WDFY4 PLXDC2 VNN1 TLR1 MERTK

7.22e-05200155678d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 SGCA ORC3 CALHM2 TLR1 TRAM2

7.22e-0520015563e0041c04e42a47257517dae8707a6454570c256
ToppCellproximal-Epithelial-Proximal_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CMYA5 CLCA2 PROM2 KCNJ1 HS3ST1 RAPGEFL1

7.22e-052001556ff2afa5c0352c214525129f9ff85afc139fe44d2
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CMYA5 ZKSCAN1 PLXDC2 PAK3 PALS2 ITIH6

7.22e-0520015567c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellsevere-unassigned|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCKAP1 DSN1 ADAM22 DGKI CEP170B

8.56e-051281555bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

CASP8 PKHD1 DGKI PLCG1 ARAP2

1.10e-041351555ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL22A1 RB1CC1 ALKBH8 PLXDC2 KCNJ1

1.49e-0414415555e948d4cb913ccd8f82262a1b4d20967aadab3ab
Diseaselongevity

ETV1 ARFGEF2 STEAP2 SDAD1 ALKBH8 KCNA1 BRAF PKHD1 ADGRL3

1.67e-052841519EFO_0004300
DiseaseAmyloidosis, Familial

TTR FGA

7.78e-0531512C0740340
Diseasecortical surface area measurement

PRKD2 SGCA KIF1B ARHGEF12 COL22A1 ADGRV1 MAST2 PLXNB2 TYR STRN PLXDC2 ADAMTS7 PKHD1 DGKI ASTN2 TWSG1 MOV10 SOS2

1.87e-04134515118EFO_0010736
Diseasehair color

FRAS1 ETV1 ADGRV1 PIGV PLXNB2 TYR PKHD1 SDF4

2.10e-043111518EFO_0003924
Diseaseimmunoglobulin superfamily DCC subclass member 4 measurement

DENND4A DPP8

2.58e-0451512EFO_0801690
DiseaseHyperphosphatasia-intellectual disability syndrome

PIGV PIGO

3.85e-0461512cv:C1855923
DiseaseAmyloidosis, hereditary systemic

TTR FGA

3.85e-0461512cv:C4081731
DiseaseMalignant neoplasm of breast

ARFGEF2 ETV4 CASP8 RB1CC1 PIK3R4 ALKBH8 BRAF CLCA2 SNX32 KCNJ1 N4BP2 PAK1 ASTN2 GALNT5 DOP1A

4.24e-04107415115C0006142
Diseasebipolar disorder (implicated_via_orthology)

ETV1 ETV4

5.37e-0471512DOID:3312 (implicated_via_orthology)
DiseaseHyperphosphatasia with Mental Retardation

PIGV PIGO

5.37e-0471512C1855923
Diseasecortical thickness

COL12A1 ARFGEF2 ARHGEF12 ADGRV1 VIT MAST2 JMJD1C ENO4 STRN PLXDC2 ADAMTS7 PKHD1 DGKI ASTN2 SOS2

6.12e-04111315115EFO_0004840
Diseasered blood cell density measurement

RALGAPA1 DENND4A FKBP9 DNAH2 ARFGEF2 ADGRV1 DPP8 MAST2 JMJD1C SNX30 LIPC PKHD1 AP3D1

6.17e-0488015113EFO_0007978
Diseaseaspergillosis (is_implicated_in)

TLR6 TLR1

7.14e-0481512DOID:13564 (is_implicated_in)
DiseaseEwings sarcoma

ETV1 ETV4

7.14e-0481512C0553580
Diseaseretinal detachment, retinal break

FRAS1 COL22A1 PLXDC2

7.62e-04351513EFO_0005773, EFO_0010698
DiseaseDisorder of eye

RPGRIP1 FRAS1 ADGRV1 TYR TTC8 MERTK

8.04e-042121516C0015397
Diseasecerebrospinal fluid biomarker measurement, t-tau measurement

COL22A1 BRAF

9.15e-0491512EFO_0004760, EFO_0006794
Diseasesnoring measurement

RTN4RL1 ADGRV1 TYR ANAPC4

9.25e-04841514EFO_0008341
DiseaseColorectal Carcinoma

ETV1 CASP8 ABCA10 FAT1 GSE1 BRAF PUS10 PKHD1 SDF4 PIGO ANAPC4

1.01e-0370215111C0009402
Diseaseciliopathy (implicated_via_orthology)

RPGRIP1 CC2D2B TTC8

1.13e-03401513DOID:0060340 (implicated_via_orthology)
Diseaseabdominal aortic calcification measurement

PIK3R4 PLXDC2

1.14e-03101512EFO_0010272
Diseasenevus count, cutaneous melanoma

CASP8 ADGRV1 PLXNB2 TYR

1.25e-03911514EFO_0000389, EFO_0004632
Diseasepneumococcal bacteremia

DOCK2 ETV1

1.39e-03111512EFO_1001925
Diseasehip geometry

MPP2 ADGRV1 ASTN2

1.49e-03441513EFO_0004685
DiseasePulmonary Thromboembolisms

FGA MERTK

1.66e-03121512C0524702
DiseasePulmonary Embolism

FGA MERTK

1.66e-03121512C0034065
DiseaseOligospermia

CGA BRWD1

1.66e-03121512C0028960
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

PLXDC2 NME7

1.96e-03131512EFO_0802114
Diseasesodium measurement

MAST2 JMJD1C GSE1 PKHD1

1.97e-031031514EFO_0009282
DiseaseNeoplasm of lung

CASP8 BRAF

2.27e-03141512cv:C0024121
DiseaseC-X-C motif chemokine 11 measurement

PPEF2 JMJD1C

2.27e-03141512EFO_0008057
DiseaseLung cancer

CASP8 BRAF

2.27e-03141512cv:C0242379
DiseaseLUNG CANCER

CASP8 BRAF

2.27e-03141512211980
Diseaselysophosphatidylcholine 15:0 measurement

LIPC PKHD1

2.27e-03141512EFO_0020941
DiseaseC-X-C motif chemokine 10 measurement

FRAS1 PPEF2 SDAD1 HS3ST1

2.42e-031091514EFO_0008056
Diseasehepatocellular carcinoma (is_implicated_in)

KIF1B CASP8 BIRC3 RYR3 PLCG1

2.44e-031811515DOID:684 (is_implicated_in)
DiseaseCiliopathies

RPGRIP1 ADGRV1 TTC8 PKHD1

2.50e-031101514C4277690
Diseaselysophosphatidylethanolamine 18:0 measurement

MATN2 LIPC

2.61e-03151512EFO_0010367
Diseaseinfant head circumference

ARFGEF2 PLCG1

2.61e-03151512EFO_0004577
DiseaseChronic Lymphocytic Leukemia

PRKD2 BIRC3 BRAF

2.84e-03551513C0023434
Diseasemigraine without aura, susceptibility to, 4

MPP2 ASTN2

2.98e-03161512MONDO_0011847
Diseasemyeloid white cell count

KIF1B CGA ETV1 ARHGEF12 CASP8 PIGV MAST2 JMJD1C EHD4 LIPC SNX32 RAPGEFL1

3.26e-0393715112EFO_0007988
DiseaseAmyotrophic lateral sclerosis

ALS2 FIG4

3.36e-03171512cv:C0002736
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR6 TLR1

3.36e-03171512DOID:8677 (biomarker_via_orthology)
Diseasecoronary artery disease

PRKD2 ETV1 ARFGEF2 ARHGEF12 LIPC SF3B3 ZKSCAN1 ADAMTS7 PKHD1 ASTN2 PLCG1 MERTK NME7 ADGRL3

3.37e-03119415114EFO_0001645
DiseaseMalignant neoplasm of skin

CASP8 TYR CSNK2A1

3.46e-03591513C0007114
DiseaseSkin Neoplasms

CASP8 TYR CSNK2A1

3.46e-03591513C0037286
Diseasecutaneous melanoma

CASP8 ADGRV1 PLXNB2 TYR

3.52e-031211514EFO_0000389
Diseasebrain volume measurement

MPP2 PRKD2 FRAS1 VIT ENO4 STRN PKHD1 ASTN2 MOV10

3.65e-035951519EFO_0006930
Diseasecutaneous melanoma, hair color

ADGRV1 PLXNB2 TYR

3.98e-03621513EFO_0000389, EFO_0003924
Diseasemelanoma

COL12A1 CASP8 ADGRV1 TYR

4.07e-031261514EFO_0000756
Diseaseoral squamous cell carcinoma (is_marker_for)

BIRC3 TTR PLCG1

4.17e-03631513DOID:0050866 (is_marker_for)
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

BRAF SOS2

4.20e-03191512C3501846
DiseaseNoonan syndrome-like disorder with loose anagen hair

BRAF SOS2

4.20e-03191512C1843181
DiseaseCardio-facio-cutaneous syndrome

BRAF SOS2

4.20e-03191512C1275081
Diseaselimited scleroderma

TTC8 TLR1

4.20e-03191512EFO_1001017
DiseaseCostello syndrome (disorder)

BRAF SOS2

4.20e-03191512C0587248
Diseasehepatocellular carcinoma (is_marker_for)

CA9 KIF1B BIRC3 TTR DSN1 ASPM

4.65e-033011516DOID:684 (is_marker_for)
Diseasecoagulation factor V measurement

PLXDC2 NME7

4.65e-03201512EFO_0008087
Diseaseurate measurement, bone density

MPP2 ATG9B FRAS1 ETV1 COL6A5 ENTPD4 STRN GSE1 CSNK2A1

4.72e-036191519EFO_0003923, EFO_0004531
Diseaset-tau:beta-amyloid 1-42 ratio measurement

MPP2 COL22A1 BRAF

4.75e-03661513EFO_0007708
Diseasehistidine measurement

TMPO ASTN2 NME7

4.75e-03661513EFO_0009769
Diseasevenous thromboembolism, fibrinogen measurement

DGKZ JMJD1C PARP10

4.95e-03671513EFO_0004286, EFO_0004623
Diseaseobesity (implicated_via_orthology)

ETV1 ETV4 PLXNB2 LIPC PRKCI

5.08e-032151515DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FPVAEELSHHENLVS

TWSG1

121

Q9GZX9
HIENDHFKVASPLET

nan

166

A8MVM7
VSKFFEHHPIPQEEA

BRAF

291

P15056
TFVAEFLTEHFNEAP

ANAPC4

446

Q9UJX5
LTEEEFLSFLHPEHS

SDF4

216

Q9BRK5
PEFQDFHDQALSSHV

CATSPER1

61

Q8NEC5
IHFTKEAPSIENHFR

C2orf69

366

Q8N8R5
HEIFENEINPEHSSD

ABCA10

361

Q8WWZ4
DALVHAQFSTHHVFP

ALS2

941

Q96Q42
PAHIDTHSAFEDEIV

ALKBH8

236

Q96BT7
TLAAQFFGHTHVDEF

SMPD1

451

P17405
EPFVAEEFAHQFHES

GSE1

1016

Q14687
DHSESFFPLLTNEHT

ADGRL3

1331

Q9HAR2
ASDHAHGVFEFSPES

ADGRV1

1856

Q8WXG9
IVTTIFQHHFPAAID

ARFGEF2

1251

Q9Y6D5
EPEENDTTQEDFHFH

ADAM22

171

Q9P0K1
NAESSIIHFEPGEDH

BIRC3

356

Q13489
GFDFVVSDLEHISPH

DOP1A

1606

Q5JWR5
FSDFPQHDIHSEGVL

ARAP2

871

Q8WZ64
LHHAYAIFTEDETPV

DNHD1

991

Q96M86
HFFHLPSGSEEAILQ

DNHD1

2911

Q96M86
PVVQSHASFTIEFDD

CEP170B

261

Q9Y4F5
FDTHALVQDLETHGF

CCDC90B

61

Q9GZT6
ASDETLHEDTVHPFV

CC2D2B

906

Q6DHV5
LHEDTVHPFVEVSFQ

CC2D2B

911

Q6DHV5
VNHVQTPFDEFDFAV

ASPM

951

Q8IZT6
HVPEHFIADGSSFVV

ASTN2

466

O75129
SSHELFNEADFIPHH

ADAMTS7

1011

Q9UKP4
FPAEIHVVHLSTAFA

CA9

246

Q16790
AVFLHHVVSQFDPAT

ARHGEF12

386

Q9NZN5
EFSEHLQEPHHTLEA

AP3D1

491

O14617
QFVPDFHSENLAFHS

ETV4

76

P43268
DHAITVADFVDHHPI

DENND4A

1656

Q7Z401
IHPSTFEGFVHLEEL

RTN4RL1

91

Q86UN2
DAHTFDFETIPHPNI

RB1CC1

696

Q8TDY2
DIFFDSHSVNAHIPQ

FAT1

701

Q14517
LEPAEVRHQDSSFAH

FHDC1

586

Q9C0D6
SLPSDFEHTIHVGFD

PAK3

71

O75914
PHGTVLHQTLDFDEF

FAM189A1

226

O60320
TEKHVFEQASNHPFL

PRKCI

301

P41743
KFHFTVSDGEHTSPE

FRAS1

1566

Q86XX4
YFQSVHESIEPTHDI

FRAS1

1916

Q86XX4
AHFASELPDFHVVSN

FRAS1

3781

Q86XX4
FAEAEEAESHFSSIP

KCNA1

346

Q09470
PHEDHVFLVANFSQI

MATN2

211

O00339
HDDFFSTTPLQHQRI

MIS18BP1

986

Q6P0N0
QHDKIDASELSFPFH

TMPO

481

P42166
HHAITQFYPDDEVTA

MERTK

141

Q12866
NFLHRHDEAFSTEPL

KIF1B

1141

O60333
FVSPEHLVESFHLTQ

JMJD1C

2481

Q15652
LTAREEHFPSAHATE

CALHM2

141

Q9HA72
EHFPSAHATEILARF

CALHM2

146

Q9HA72
EHPDEFGFLLDHVQT

PLXNA3

1096

P51805
PHFIFDVHVHEVVDA

PLXNB2

1696

O15031
HSDVPSSAHAGFFVE

PCED1B

356

Q96HM7
HINEEDTVPLSHFDE

ETV1

441

P50549
FEDFQIRPHALTVHS

PRKD2

131

Q9BZL6
PDDANFVDAIHTFTR

LIPC

211

P11150
FEEHVQASHFEGLIT

MARCHF6

321

O60337
EESPLETAASFFHNV

DSE

576

Q9UL01
ETAASFFHNVDVPFE

DSE

581

Q9UL01
FFHNVDVPFEETVVD

DSE

586

Q9UL01
HEFHSPALEDADFEN

EHD4

46

Q9H223
EPHFQSLLETHDSVA

MPP2

121

Q14168
LNSDEPKTAHIDVHF

ITGA6

646

P23229
HEERFQFPSHVTDVS

CDC42BPB

296

Q9Y5S2
SLSVDHFNAVLEEFP

HCN3

516

Q9P1Z3
HIPFLVSSIEDFKDH

NCKAP1

931

Q9Y2A7
ALHAYQESFTPTEEH

SMPD4

351

Q9NXE4
IHADIPEFLFEHLSS

MEI1

321

Q5TIA1
SVFLHVLHSAPDVQD

CGA

16

P01215
SLPSDFEHTIHVGFD

PAK1

76

Q13153
LHPSDHENIQAFSDE

PARP14

1171

Q460N5
VFDIHVIDFHNPSDS

FKBP9

356

O95302
EPHFQSLLEAHDIVA

PALS2

86

Q9NZW5
SVVFAHPETVEDCHF

PUS10

211

Q3MIT2
DDHHLPTVQFDFTGI

RPA1

291

P27694
HSENQHLVSPEALDF

CSNK2A3

286

Q8NEV1
KSENFHPVFEHLDST

BCLAF3

446

A2AJT9
DEEKQHFIPFHPVTA

DOCK2

341

Q92608
PAETHVFTVEDFDAF

COL12A1

591

Q99715
FSLGFDAHVTLEFHE

DGKI

531

O75912
TLDQADPFAHVAALH

FIG4

346

Q92562
STSVFHPELVNHIVF

GALNT5

886

Q7Z7M9
GDSSLVFHVENFDHL

COL6A5

776

A8TX70
ISYAVPFEDTHHVLE

CMYA5

3336

Q8N3K9
DIFHVFPQSHEEEIE

DPP8

451

Q6V1X1
AVFSDLHPFHEESTN

GRPR

176

P30550
LHPFHEESTNQTFIS

GRPR

181

P30550
HDHQLESSLSPVEVF

DSN1

21

Q9H410
EPKSAHVFHVSDFNA

COL22A1

191

Q8NFW1
EIIDFFHHFTVDVAG

ATG9B

651

Q674R7
GHADEVFVLETHPFD

BRWD1

466

Q9NSI6
TTTFEELHFEIKPHD

CASP8

271

Q14790
HSENQHLVSPEALDF

CSNK2A1

286

P68400
DEFPLHFKNVHTDIQ

FBXO40

486

Q9UH90
HRHPDEAAFFDTAST

FGA

511

P02671
HFLTKHFSTESVPDE

MAST2

271

Q6P0Q8
TSVLFNPHAEAHEAI

ITIH6

56

Q6UXX5
STHFEVHENALPELA

ENO4

106

A6NNW6
PNHVTDDFAAHLTLE

KCMF1

121

Q9P0J7
VTSFPDADAFHHQVH

EMD

121

P50402
FSLGFDAHVTLEFHE

DGKZ

451

Q13574
DHVDEVTCLAFHPTE

CSTF1

171

Q05048
PTHDDVTFEAVAQAF

FLAD1

181

Q8NFF5
QEHDAILEHFAQDPT

DNAH2

96

Q9P225
LDVHDVTHVYNFDFP

DDX43

551

Q9NXZ2
FHVDHQSRPFFNELI

NME7

136

Q9Y5B8
CFPSEDHLEEFIAEH

FAM153B

151

P0C7A2
FHPDQEDQFFSLVHE

TBRG4

381

Q969Z0
DHFIPSSHNDRDFLT

PPEF2

71

O14830
SIFVIFHDTQALPTH

PARP10

986

Q53GL7
ESEENVEHIPFSHNH

IYD

66

Q6PHW0
QDFIIISSQHLHEFP

ORC3

231

Q9UBD5
ETQPLHEVVYFSAAH

ORC3

571

Q9UBD5
LHPDVAAAENEVHFF

HS3ST1

76

O14792
HADVDVSPRLVHFSA

KCTD11

91

Q693B1
FEESIHDVAFHPSKC

STRN

751

O43815
IHFHFSKVIDLDPQE

RPGRIP1

1171

Q96KN7
LSQDILSPEFHEHFN

SOS2

296

Q07890
SAQFPIDHFTHIFID

MOV10

631

Q9HCE1
TADFEQDTEKEHHTP

RNF113B

111

Q8IZP6
DPLFKHFHSVDIQAS

RGPD2

626

P0DJD1
IPVHFDFLFSDSHAE

ENTPD4

201

Q9Y227
AFPHTEEEVEVDSHA

PLXDC2

46

Q6UX71
ASEFFPHVVDVTHHE

STEAP2

66

Q8NFT2
HSFPRTVENIFHVSF

NSMCE4A

296

Q9NXX6
HELQSPHVFLGESFI

PKHD1

3501

P08F94
VFNFSAIHLIHDPQD

SDAD1

281

Q9NVU7
VHEQAFSSHILEPIE

DZIP1

491

Q86YF9
FVHTLDHETFLSLPE

SGCA

36

Q16586
IIDHNSVSHPSADFF

TLR1

496

Q15399
TVEAFVERDSLHFPH

CLCA2

606

Q9UQC9
HFFPEQVLNKIEDHS

PIK3R4

271

Q99570
QALFNAIIPDHHAEA

PIGV

26

Q9NUD9
KSEAAFPDHVDTQHL

TTC8

516

Q8TAM2
DVLCNEFHTPHDAAF

THOC2

801

Q8NI27
SAHPVEVFSFDLHEP

TMEM175

241

Q9BSA9
FHDPAVTLVKDFHVD

VNN1

216

O95497
QHHLEPTTFEDFAAQ

RALGAPA1

2006

Q6GYQ0
RITDHPVLSFNEHFN

SNX30

186

Q5VWJ9
ADFSQVPSVDHVLHQ

PROM2

321

Q8N271
FDTTPHGFETHTLQE

RYR3

4801

Q15413
FDSPHEDIVFETDHI

STX11

26

O75558
DAVLADFASPFHERH

RGCC

36

Q9H4X1
PLFSQEFVIHNHADI

TRAM2

11

Q15035
RSTHEFLHEVPAASE

VPS16

321

Q9H269
ANDPIFLLHHAFVDS

TYR

381

P14679
TFFPALHESLHSEDF

WDFY4

2356

Q6ZS81
LHATSFDVVLTDPFH

UGT1A5

141

P35504
LEVIATHPARDHSFF

VIT

636

Q6UXI7
THPARDHSFFVDEFD

VIT

641

Q6UXI7
PFEDFRISQEHLADH

PLCG1

1256

P19174
IGILVPFTSHEDHDF

SF3B3

1126

Q15393
PFTSHEDHDFFQHVE

SF3B3

1131

Q15393
IIDHNSVSHPSADFF

TLR6

501

Q9Y2C9
TALFLFAHELHPQET

VN1R5

201

Q7Z5H4
FAHELHPQETVFHTN

VN1R5

206

Q7Z5H4
DALRFDFAQPQHSHV

PIGO

76

Q8TEQ8
ALGISPFHEHAEVVF

TTR

101

P02766
PFHEHAEVVFTANDS

TTR

106

P02766
DPVQESSSFDLHHEA

ZKSCAN1

161

P17029
FFNVHSAVLIEDVPF

RNASEK

71

Q6P5S7
HRVEPEDVANHLTAF

RAPGEFL1

421

Q9UHV5
PHFAQTEFSVVRQHE

SNX32

51

Q86XE0
RSQDHFHVFVGDLSP

TIA1

101

P31483
HFLQPFGDHIISVDT

WDR36

166

Q8NI36
FHNFSKTVEVETPHC

KCNJ1

341

P48048
SLPEEINFIHSVFDA

KRT75

276

O95678
DNIHSPSHFSDIFNF

N4BP2

1276

Q86UW6