Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF366 HELT PDX1 KLF15 SOX18 CC2D1B IRF5 RELB BCL11A KDM6B GTF2IRD1 MEF2D ZBTB7A WIZ NFATC1 NFATC4 EGR4 ZFHX2 INSM2	4.04e-05	1244	109	19	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF366 HELT PDX1 KLF15 SOX18 CC2D1B IRF5 RELB BCL11A KDM6B GTF2IRD1 MEF2D ZBTB7A WIZ NFATC1 NFATC4 EGR4 ZFHX2 INSM2	5.41e-05	1271	109	19	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF366 HELT PDX1 KLF15 SOX18 CC2D1B IRF5 RELB BCL11A KDM6B GTF2IRD1 MEF2D ZBTB7A WIZ NFATC1 NFATC4 EGR4 ZFHX2 INSM2	3.25e-04	1459	109	19	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	HELT CC2D1B BCL11A GTF2IRD1 ZBTB7A NFATC1 NFATC4 INSM2	3.73e-04	320	109	8	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	HELT CC2D1B BCL11A GTF2IRD1 ZBTB7A NFATC1 NFATC4 INSM2	4.22e-04	326	109	8	GO:0001217
Domain	RNase_Zc3h12a	ZC3H12A ZC3H12B ZC3H12C	6.65e-06	7	109	3	PF11977
Domain	RNase_Zc3h12_NYN	ZC3H12A ZC3H12B ZC3H12C	6.65e-06	7	109	3	IPR021869
Domain	RHD_dimer	RELB NFATC1 NFATC4	2.25e-05	10	109	3	IPR032397
Domain	RHD_dimer	RELB NFATC1 NFATC4	2.25e-05	10	109	3	PF16179
Domain	NFkB/Dor	RELB NFATC1 NFATC4	2.25e-05	10	109	3	IPR000451
Domain	REL_1	RELB NFATC1 NFATC4	2.25e-05	10	109	3	PS01204
Domain	RHD_DNA_bind_dom	RELB NFATC1 NFATC4	2.25e-05	10	109	3	IPR011539
Domain	RHD_DNA_bind	RELB NFATC1 NFATC4	2.25e-05	10	109	3	PF00554
Domain	REL_2	RELB NFATC1 NFATC4	2.25e-05	10	109	3	PS50254
Domain	-	RELB NFATC1 NFATC4	2.25e-05	10	109	3	2.60.40.340
Domain	DUF2476	PRR23A PRR23B	2.01e-04	4	109	2	PF10630
Domain	PRR23	PRR23A PRR23B	2.01e-04	4	109	2	IPR018903
Domain	Znf_C2H2-like	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 FBXO41 ZFHX2 PRDM13 INSM2 ZFTA ZNF687	2.18e-04	796	109	14	IPR015880
Domain	ZnF_C2H2	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 FBXO41 ZFHX2 PRDM13 INSM2 ZFTA ZNF687	2.54e-04	808	109	14	SM00355
Domain	NFAT	NFATC1 NFATC4	3.34e-04	5	109	2	IPR008366
Domain	F_BAR	GMIP ARHGAP4 ARHGAP45	4.05e-04	25	109	3	IPR031160
Domain	F_BAR	GMIP ARHGAP4 ARHGAP45	4.05e-04	25	109	3	PS51741
Domain	RhoGAP	GMIP ARHGAP4 PIK3R2 ARHGAP45	4.72e-04	62	109	4	SM00324
Domain	RhoGAP	GMIP ARHGAP4 PIK3R2 ARHGAP45	5.02e-04	63	109	4	PF00620
Domain	IPT	RELB NFATC1 NFATC4	5.11e-04	27	109	3	SM00429
Domain	RHOGAP	GMIP ARHGAP4 PIK3R2 ARHGAP45	5.33e-04	64	109	4	PS50238
Domain	RhoGAP_dom	GMIP ARHGAP4 PIK3R2 ARHGAP45	5.33e-04	64	109	4	IPR000198
Domain	-	GMIP ARHGAP4 PIK3R2 ARHGAP45	5.33e-04	64	109	4	1.10.555.10
Domain	zf-C2H2	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 EGR4 FBXO41 ZFHX2 PRDM13 INSM2 ZNF687	7.23e-04	693	109	12	PF00096
Domain	TIG	RELB NFATC1 NFATC4	7.72e-04	31	109	3	PF01833
Domain	Znf_C2H2	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 FBXO41 ZFHX2 PRDM13 INSM2 ZNF687	8.26e-04	805	109	13	IPR007087
Domain	IPT	RELB NFATC1 NFATC4	8.48e-04	32	109	3	IPR002909
Domain	DHC_N1	DNAH5 DNAH9	9.24e-04	8	109	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH9	9.24e-04	8	109	2	IPR013594
Domain	Rho_GTPase_activation_prot	GMIP ARHGAP4 PIK3R2 ARHGAP45	1.76e-03	88	109	4	IPR008936
Domain	ZINC_FINGER_C2H2_2	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 ZFHX2 PRDM13 INSM2 ZNF687	1.88e-03	775	109	12	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 ZFHX2 PRDM13 INSM2 ZNF687	1.92e-03	777	109	12	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 EGR4 ZFHX2 PRDM13 INSM2 ZNF687	2.43e-03	694	109	11	IPR013087
Domain	-	EPB41L3 TLN1 ACBD3	2.93e-03	49	109	3	1.20.80.10
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH9	2.93e-03	14	109	2	IPR024317
Domain	Dynein_HC_stalk	DNAH5 DNAH9	2.93e-03	14	109	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH9	2.93e-03	14	109	2	IPR013602
Domain	DHC_N2	DNAH5 DNAH9	2.93e-03	14	109	2	PF08393
Domain	MT	DNAH5 DNAH9	2.93e-03	14	109	2	PF12777
Domain	AAA_8	DNAH5 DNAH9	2.93e-03	14	109	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH5 DNAH9	2.93e-03	14	109	2	IPR011704
Domain	AAA_5	DNAH5 DNAH9	2.93e-03	14	109	2	PF07728
Domain	FERM/acyl-CoA-bd_prot_3-hlx	EPB41L3 TLN1 ACBD3	3.10e-03	50	109	3	IPR014352
Domain	DHC_fam	DNAH5 DNAH9	3.37e-03	15	109	2	IPR026983
Domain	Dynein_heavy_dom	DNAH5 DNAH9	3.37e-03	15	109	2	IPR004273
Domain	Dynein_heavy	DNAH5 DNAH9	3.37e-03	15	109	2	PF03028
Domain	p53-like_TF_DNA-bd	RELB NFATC1 NFATC4	3.66e-03	53	109	3	IPR008967
Domain	ZF_C3H1	ZC3H12A ZC3H12B ZC3H12C	4.73e-03	58	109	3	PS50103
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6B STK36 ANKRD9 IRF5 RELB ZFPM1 KDM6B GTF2IRD1 RYR1 ACOX3 FAM83H RABL6 FZD7 EPS15L1 WIZ MAP1S NFATC1 TLN1 SLC52A2 CEP170B ZNF687 EVI5L	4.83e-12	1105	110	22	35748872
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	RNF44 SOX18 IRF5 RELB BCL11A GTF2IRD1 ZYX MEF2D MEX3C LSR NFATC4 ZFHX2 TIGD5 ZNF687	5.71e-08	709	110	14	22988430
Pubmed	A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.	ZC3H12A ZC3H12B ZC3H12C	1.23e-07	4	110	3	18178554
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AMBN BCL11A EPB41L3 FAM83H ARHGAP4 ZBTB7A ZNF469 WIZ PIK3R2 TIGD5 HAX1 TOPORS VPS51 CEP170B ZNF687 EVI5L	4.69e-07	1116	110	16	31753913
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GAK SCYL1 CBLB ZYX ACOX3 FAM83H MAP1S NFATC4 PIK3R2 TLN1 HAX1 VPS51 ZNF687	6.33e-06	910	110	13	36736316
Pubmed	The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.	TPSAB1 TPSB2	9.91e-06	2	110	2	10500112
Pubmed	KLF15 regulates slow myosin heavy chain expression through NFATc1 in C2C12 myotubes.	KLF15 NFATC1	9.91e-06	2	110	2	24680826
Pubmed	Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.	TPSAB1 TPSB2	9.91e-06	2	110	2	8434231
Pubmed	Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.	KDM6B NFATC1	9.91e-06	2	110	2	21735477
Pubmed	Cloning and characterization of a second complementary DNA for human tryptase.	TPSAB1 TPSB2	9.91e-06	2	110	2	2203827
Pubmed	Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.	TPSAB1 TPSB2	9.91e-06	2	110	2	10898108
Pubmed	Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells.	SIRT7 MEF2D	9.91e-06	2	110	2	31678303
Pubmed	Pokemon promotes the invasiveness of hepatocellular carcinoma by enhancing MEF2D transcription.	MEF2D ZBTB7A	9.91e-06	2	110	2	26797719
Pubmed	Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains.	RYR1 GPNMB	9.91e-06	2	110	2	21933672
Pubmed	Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.	TPSAB1 TPSB2	9.91e-06	2	110	2	9521329
Pubmed	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.	TPSAB1 TPSB2	9.91e-06	2	110	2	2187193
Pubmed	Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.	TPSAB1 TPSB2	9.91e-06	2	110	2	15567416
Pubmed	Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.	TPSAB1 TPSB2	9.91e-06	2	110	2	10391906
Pubmed	The human mast cell tryptase tetramer: a fascinating riddle solved by structure.	TPSAB1 TPSB2	9.91e-06	2	110	2	10708850
Pubmed	Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology.	ZC3H12A ZC3H12C	9.91e-06	2	110	2	34298932
Pubmed	Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.	TPSAB1 TPSB2	9.91e-06	2	110	2	17449330
Pubmed	Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells.	NFATC1 NFATC4	9.91e-06	2	110	2	28760926
Pubmed	Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.	TPSAB1 TPSB2	9.91e-06	2	110	2	31337736
Pubmed	Regnase-1 D141N mutation induces CD4+ T cell-mediated lung granuloma formation via upregulation of Pim2.	ZC3H12A PIM2	9.91e-06	2	110	2	38700370
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KDM6B ARHGEF17 NACAD DNAH9 PDZD2	2.07e-05	104	110	5	9205841
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	ZBTB7A WIZ EGR4	2.87e-05	19	110	3	30385546
Pubmed	Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation.	CBLB NFATC1	2.97e-05	3	110	2	26173181
Pubmed	Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.	DNAH5 DNAH9	2.97e-05	3	110	2	15750039
Pubmed	Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.	KLF15 SIRT7	2.97e-05	3	110	2	36334846
Pubmed	Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.	DNAH5 DNAH9	2.97e-05	3	110	2	15845866
Pubmed	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.	TPSAB1 TPSB2	2.97e-05	3	110	2	9920877
Pubmed	Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.	TPSAB1 TPSB2	2.97e-05	3	110	2	19748655
Pubmed	A census of human transcription factors: function, expression and evolution.	HELT PDX1 KLF15 SOX18 IRF5 RELB ZFPM1 MEF2D ZBTB7A NFATC1 NFATC4 ZFHX2	3.15e-05	908	110	12	19274049
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	GAK RABL6 EPS15L1 WIZ TOPORS VPS51 ACBD3	3.57e-05	285	110	7	34369648
Pubmed	Alternative splicing and expression of human and mouse NFAT genes.	NFATC1 NFATC4	5.92e-05	4	110	2	18675896
Pubmed	Transcription factors of the NFAT family: regulation and function.	NFATC1 NFATC4	5.92e-05	4	110	2	9143705
Pubmed	Nuclear factor of activated T cells is activated in the endothelium of retinal microvessels in diabetic mice.	NFATC1 NFATC4	5.92e-05	4	110	2	25918731
Pubmed	NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis.	NFATC1 NFATC4	5.92e-05	4	110	2	26527057
Pubmed	Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.	BCL11A ZBTB7A	5.92e-05	4	110	2	29610478
Pubmed	HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.	NFATC1 NFATC4	5.92e-05	4	110	2	16260021
Pubmed	Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway.	MEF2D NFATC1	5.92e-05	4	110	2	17111365
Pubmed	ZC3H12B/MCPIP2, a new active member of the ZC3H12 family.	ZC3H12A ZC3H12B	5.92e-05	4	110	2	30988100
Pubmed	The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis.	NFATC1 NFATC4	5.92e-05	4	110	2	24970700
Pubmed	DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.	DNAH5 DNAH9	5.92e-05	4	110	2	18950741
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	PDX1 KLF15 SOX18 IRF5 MEF2D ZBTB7A NFATC1 NFATC4 EGR4	6.01e-05	544	110	9	28473536
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	STK36 SCYL1 RELB ZNF469 MAP1S NFATC4 PIK3R2 TLN1	6.98e-05	430	110	8	35044719
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL1 EPB41L3 ZYX FAM83H LSR EPS15L1 TLN1 PALM3 ACBD3	8.03e-05	565	110	9	25468996
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	GTF2IRD1 ZYX RABL6 EPS15L1 TLN1 DNAH9	8.59e-05	226	110	6	31452512
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CARMIL2 PARD3B EPB41L3 ARHGEF17 ZYX MEF2D MEX3C FAM83H LSR MAP3K10 CEP170B	9.25e-05	861	110	11	36931259
Pubmed	Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.	NFATC1 NFATC4	9.85e-05	5	110	2	17693409
Pubmed	Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.	NFATC1 NFATC4	9.85e-05	5	110	2	22593154
Pubmed	DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.	DNAH5 DNAH9	9.85e-05	5	110	2	26909801
Pubmed	Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.	TPSAB1 TPSB2	9.85e-05	5	110	2	10843716
Pubmed	ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.	DNAH5 DNAH9	9.85e-05	5	110	2	23849778
Pubmed	Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.	NFATC1 EGR4	9.85e-05	5	110	2	12560487
Pubmed	NFAT: ubiquitous regulator of cell differentiation and adaptation.	NFATC1 NFATC4	9.85e-05	5	110	2	11877454
Pubmed	The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.	DNAH5 DNAH9	9.85e-05	5	110	2	23525783
Pubmed	Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif.	NFATC1 NFATC4	9.85e-05	5	110	2	7999066
Pubmed	Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT.	NFATC1 NFATC4	9.85e-05	5	110	2	10089876
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ZC3H12A SCYL1 RELB GMIP ZYX MEF2D MEX3C RABL6 EPS15L1 ZC3H12C HAX1 EVI5L	1.13e-04	1038	110	12	26673895
Pubmed	CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.	DNAH5 DNAH9	1.47e-04	6	110	2	33347437
Pubmed	Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.	NFATC1 NFATC4	1.47e-04	6	110	2	24352425
Pubmed	A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.	NFATC1 NFATC4	1.47e-04	6	110	2	16141075
Pubmed	New developments in the genetics and activation of mast cell proteases.	TPSAB1 TPSB2	1.47e-04	6	110	2	12217407
Pubmed	p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.	CBLB PIK3R2	1.47e-04	6	110	2	19190244
Pubmed	Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering.	NFATC1 NFATC4	1.47e-04	6	110	2	8814265
Pubmed	Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.	NFATC1 NFATC4	1.47e-04	6	110	2	21880741
Pubmed	Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.	NFATC1 NFATC4	1.47e-04	6	110	2	12788643
Pubmed	The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins.	NFATC1 NFATC4	1.47e-04	6	110	2	25728138
Pubmed	A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis.	NFATC1 NFATC4	1.47e-04	6	110	2	15339668
Pubmed	Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells.	NFATC1 NFATC4	1.47e-04	6	110	2	16690925
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	WDR33 GMIP EPB41L3 ARHGEF17 ZYX ARHGAP4 EPS15L1 PIK3R2 TLN1 HAX1 EVI5L	1.59e-04	916	110	11	32203420
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GAK CARMIL2 LZTS3 BCL11A EPB41L3 ARHGEF17 EPS15L1 MAP1S TLN1 FBXO41 MAST1 HAX1 VPS51 CEP170B	1.72e-04	1431	110	14	37142655
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZFPM1 GTF2IRD1 ZYX MEF2D PCF11 ZBTB7A EPS15L1 MAP1S TOPORS ZNF687	1.78e-04	774	110	10	15302935
Pubmed	A multipotent progenitor domain guides pancreatic organogenesis.	PDX1 SOX18 MEF2D LSR	2.05e-04	91	110	4	17609113
Pubmed	Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.	BCL11A ZBTB7A	2.06e-04	7	110	2	26816381
Pubmed	NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.	NFATC1 NFATC4	2.06e-04	7	110	2	16554754
Pubmed	Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells.	NFATC1 NFATC4	2.06e-04	7	110	2	18097055
Pubmed	Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.	CBLB NFATC1	2.06e-04	7	110	2	20037154
Pubmed	NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.	NFATC1 NFATC4	2.06e-04	7	110	2	18218901
Pubmed	Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.	NFATC1 NFATC4	2.06e-04	7	110	2	17430895
Pubmed	Calcium/NFAT signalling promotes early nephrogenesis.	NFATC1 NFATC4	2.06e-04	7	110	2	21295565
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH5 DNAH9	2.06e-04	7	110	2	31178125
Pubmed	Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.	RELB NFATC1 NFATC4	2.40e-04	38	110	3	12482669
Pubmed	The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.	ZYX TLN1	2.74e-04	8	110	2	12695497
Pubmed	Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.	NFATC1 NFATC4	2.74e-04	8	110	2	12370307
Pubmed	Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity.	NFATC1 NFATC4	2.74e-04	8	110	2	7957556
Pubmed	Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.	DNAH5 DNAH9	3.52e-04	9	110	2	27353389
Pubmed	A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.	PRR23A PRR23B	4.39e-04	10	110	2	24565867
Pubmed	Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling.	NFATC1 NFATC4	4.39e-04	10	110	2	19710169
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	GAK SCYL1 EPB41L3 ZYX EPS15L1 TLN1 PRMT7 ACBD3	4.60e-04	568	110	8	37774976
Pubmed	Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.	NFATC1 NFATC4	5.35e-04	11	110	2	20824138
Pubmed	Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.	CBLB PIK3R2	5.35e-04	11	110	2	20598684
Pubmed	The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.	LZTS3 VSIR	5.35e-04	11	110	2	21949185
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	GAK EPB41L3 ZYX RABL6 EPS15L1 TLN1 ACBD3	5.79e-04	449	110	7	31732153
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	GAK ZYX EPS15L1 TLN1 PRMT7	6.36e-04	216	110	5	31519766
Pubmed	A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library.	BEND5 SIRT7	6.41e-04	12	110	2	9776767
Pubmed	Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.	DNAH5 DNAH9	7.56e-04	13	110	2	35942101
Pubmed	Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.	CBLB EPS15L1	7.56e-04	13	110	2	12218189
Pubmed	POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.	BCL11A ZFPM1	7.56e-04	13	110	2	29898395
Interaction	TOP3B interactions	SEMA6B STK36 ANKRD9 IRF5 RELB ZFPM1 KDM6B GTF2IRD1 RYR1 ACOX3 FAM83H RABL6 FZD7 EPS15L1 WIZ MAP1S NFATC1 TLN1 SLC52A2 CEP170B ZNF687 EVI5L	6.65e-06	1470	106	22	int:TOP3B
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	SEMA6B PRR22 GMIP ZBTB7A EPS15L1 WIZ MAP1S PIK3R2 PALM3 MAST1 ARHGAP45 EVI5L	5.67e-07	797	111	12	chr19p13
Cytoband	8q24.3	ADGRB1 FAM83H TIGD5 SLC52A2	1.70e-04	113	111	4	8q24.3
Cytoband	11q13	SCYL1 PCF11 ZFTA VPS51	2.01e-04	118	111	4	11q13
Cytoband	19p13.11	GMIP EPS15L1 MAP1S	7.56e-04	73	111	3	19p13.11
Cytoband	7q32	IRF5 ZYX	1.54e-03	24	111	2	7q32
Cytoband	Xq12	ZC3H12B YIPF6	1.81e-03	26	111	2	Xq12
GeneFamily	Nuclear factors of activated T-cells	NFATC1 NFATC4	1.68e-04	5	75	2	665
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF366 KLF15 BCL11A ZFPM1 ZBTB7A ZNF469 WIZ EGR4 ZNF747 ZFHX2 INSM2	1.73e-04	718	75	11	28
GeneFamily	Zinc fingers CCCH-type	ZC3H12A ZC3H12B ZC3H12C	4.08e-04	35	75	3	73
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	GMIP ARHGAP4 ARHGAP45	1.17e-03	50	75	3	721
GeneFamily	Dyneins, axonemal	DNAH5 DNAH9	2.22e-03	17	75	2	536
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	ARHGAP4 ARHGAP45	4.06e-03	23	75	2	1288
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	ZC3H12A LZTS3 RNF44 RELB HS1BP3 SIRT7 KDM6B GTF2IRD1 CBLB MEF2D FZD7 MAP1S TOPORS ARHGAP45 ACBD3 PDZD2	3.84e-07	822	111	16	M6782
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TPSAB1 BEND5 EGR4 DNAH9 TPSB2	8.69e-06	111	111	5	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	ARHGEF17 NACAD ZYX VSIR FZD7 ZNF469	9.52e-06	195	111	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	BEND5 PRR22 RYR1 INSM2 DNAH9	3.06e-05	144	111	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC16A13 FAM83H MAP1S ZFTA DISP1	3.37e-05	147	111	5	b2196046656157d7fcf5b5d1cec7bf521b1e5d8e
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TPSAB1 BEND5 ARHGEF17 ZFHX2 TPSB2	3.60e-05	149	111	5	e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TPSAB1 BEND5 ARHGEF17 ZFHX2 TPSB2	3.60e-05	149	111	5	6a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF366 RNF44 HS6ST1 FBXO41 TIGD5	3.60e-05	149	111	5	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SLC16A13 FAM83H MAP1S ZFTA DISP1	3.60e-05	149	111	5	4034805c4eefb8bfb3a357273ccbdb77283ea4a5
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF366 RNF44 HS6ST1 FBXO41 TIGD5	3.72e-05	150	111	5	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPSAB1 BCL11A ATP10A RYR1 TPSB2	5.05e-05	160	111	5	fe9970c160159b35f6599ed13c89cfb49264d554
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 VSIR ARHGAP4 ARHGAP45 TPSB2	5.20e-05	161	111	5	16f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 VSIR ARHGAP4 ARHGAP45 TPSB2	5.20e-05	161	111	5	f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 VSIR ARHGAP4 ARHGAP45 TPSB2	5.20e-05	161	111	5	58a32a1033f379579697bda1bbf047a088e4a34f
ToppCell	droplet-Marrow-nan-21m-Hematologic-erythroid_progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIM2 BEND5 RYR1 EXOC3L4 ZC3H12C	5.36e-05	162	111	5	d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 SLC16A13 ACOT6 PALM3 NEURL1B	6.55e-05	169	111	5	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6B EPB41L3 ZCCHC3 HS6ST1 ZC3H12C	7.31e-05	173	111	5	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 PIM2 ATP10A NFATC1 ARHGAP45	7.93e-05	176	111	5	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 PIM2 ATP10A NFATC1 ARHGAP45	7.93e-05	176	111	5	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STK36 KLF15 PRR22 RABL6 MAMSTR	8.15e-05	177	111	5	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LZTS3 ZC3H12B LSR PIK3R2 PALM3	8.37e-05	178	111	5	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 PIM2 ATP10A NFATC1 ARHGAP45	8.82e-05	180	111	5	dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCell	Control-Classical_Monocyte-cMono_4\|Control / Disease condition and Cell class	RELB KDM6B VSIR ZBTB7A MAP1S	9.05e-05	181	111	5	f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCell	LPS_only-Lymphocytic_NKT-T_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 PIM2 ATP10A NFATC1 ARHGAP45	9.05e-05	181	111	5	a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCell	Control-Myeloid-DC1\|Control / Condition, Lineage and Cell class	BEND5 ZNF366 PRR22 RELB BCL11A	9.05e-05	181	111	5	5a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ZNF366 SOX18 ZNF469 NEURL1B	9.53e-05	183	111	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6B ZNF366 SOX18 ZNF469 NEURL1B	9.53e-05	183	111	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 IGFN1 DNAH5 USH2A DNAH9	9.78e-05	184	111	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 IGFN1 DNAH5 USH2A DNAH9	9.78e-05	184	111	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 IGFN1 DNAH5 USH2A DNAH9	9.78e-05	184	111	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TPSAB1 PIM2 GTF2IRD1 HS6ST1 TPSB2	1.00e-04	185	111	5	3fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEMA6B MEF2D ZBTB7A TLN1 USH2A	1.03e-04	186	111	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	TPSAB1 PIM2 DNAH5 DNAH9 TPSB2	1.08e-04	188	111	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	facs-Skin-Anagen-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NACAD MEF2D ZCCHC3 ZFTA	1.15e-04	100	111	4	97ca9cda55a05fbb4d1f5d61f847c965e014f05c
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B RELB KDM6B EPB41L3 ZC3H12C	1.16e-04	191	111	5	0b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCell	IPF-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	KDM6B EPB41L3 CBLB VSIR GPNMB	1.25e-04	194	111	5	da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell	5'-Airway_Nasal-Immune_Myeloid\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BCL11A KDM6B EPB41L3 ZNF469 TLN1	1.31e-04	196	111	5	9c942bf9fc78caa173d2c7de5fe4c17f076c623b
ToppCell	PCW_13-14-Endothelial-Endothelial_immature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA6B ZNF366 SOX18 VSIR NEURL1B	1.31e-04	196	111	5	9ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCell	COVID-19-Heart-Fib_+_CM\|Heart / Disease (COVID-19 only), tissue and cell type	IGFN1 ACOT6 RYR1 MAMSTR	1.33e-04	104	111	4	0b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ZNF366 SOX18 VSIR LSR NEURL1B	1.35e-04	197	111	5	a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF17 ATP10A FZD7 NFATC4 NEURL1B	1.35e-04	197	111	5	bc6c530330907a5ec823cc243c8e9c9e340cfb9c
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA6B ZNF366 SOX18 VSIR NEURL1B	1.35e-04	197	111	5	4e9221cb02122aed2981c3c9157e847a3710e323
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZNF366 SOX18 VSIR LSR NEURL1B	1.35e-04	197	111	5	21a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B KDM6B EPB41L3 ZNF469 TLN1	1.35e-04	197	111	5	515a2d0ee2bd3fc0a5a0c315e2b0c752e6af7406
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B KDM6B EPB41L3 ZNF469 TLN1	1.35e-04	197	111	5	bfa04e5f4156a01df4217b1f59676edb0a7563e1
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF17 ATP10A FZD7 NFATC4 NEURL1B	1.35e-04	197	111	5	77fe092aae8f05fe137680506892d2f61071d6ea
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B KDM6B EPB41L3 ZNF469 TLN1	1.35e-04	197	111	5	4fccdc69ab4b966de6465f06677435e6f6e6abcd
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-IPC_like-IPCs\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	GMIP DLL3 PRDM13 ZC3H12C NEURL1B	1.38e-04	198	111	5	b3488e916fff9a4ff62eb897d3783c93296dbd65
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BEND5 KLF15 NACAD DLL3 ZFHX2	1.38e-04	198	111	5	d6812494874be0c14361ac2ac3e418b335bb8f55
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B KDM6B EPB41L3 TLN1 ZC3H12C	1.38e-04	198	111	5	3a1707318814dabdec48f91fa6bd223f5b879653
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-IPC_like\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	GMIP DLL3 PRDM13 ZC3H12C NEURL1B	1.38e-04	198	111	5	6d99901d4df24eb3c5cca80afd9a81eb7ee8fcf1
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	IRF5 VSIR RYR1 PALM3 ARHGAP45	1.44e-04	200	111	5	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TPSAB1 BCL11A KDM6B HS6ST1 TPSB2	1.44e-04	200	111	5	a338b2b94901e4614ef78e82f580b67891f7c849
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC117 TPSAB1 PCF11 HS6ST1 TPSB2	1.44e-04	200	111	5	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC117 TPSAB1 PCF11 HS6ST1 TPSB2	1.44e-04	200	111	5	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Mast_cell\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TPSAB1 BCL11A KDM6B HS6ST1 TPSB2	1.44e-04	200	111	5	21de2cf284c8d2aa464f3d403f0e292e1f654e0a
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF17 NFATC4 ZFTA DISP1 ZNF687	1.44e-04	200	111	5	8a4c210a3130f7baedf15ecbc0f4903b97da0352
Disease	basophil measurement	TPSAB1 ZFPM1 ZNF469 TPSB2	6.82e-05	60	107	4	EFO_0803539
Disease	N6,N6,N6-trimethyllysine measurement	SCYL1 PRMT7	1.29e-04	5	107	2	EFO_0800126
Disease	basophil percentage of leukocytes	ZFPM1 GMIP ZYX RYR1 ZNF469 PIK3R2	2.65e-04	243	107	6	EFO_0007992
Disease	tryptase beta-2 measurement	TPSAB1 TPSB2	4.61e-04	9	107	2	EFO_0008306
Disease	serum gamma-glutamyl transferase measurement	ANKRD9 PDX1 KLF15 ZFPM1 CBLB ZYX MAP1S EXOC3L4 TLN1 ZNF747 PALM3	4.92e-04	914	107	11	EFO_0004532
Disease	Primary Ciliary Dyskinesia	STK36 DNAH5 DNAH9	6.69e-04	47	107	3	C4551720
Disease	lymphocyte count	CARMIL2 IRF5 ZFPM1 VSIR ARHGAP4 ZBTB7A LSR EPS15L1 ZNF469 NFATC1 HS6ST1 TLN1 NEURL1B ARHGAP45	8.33e-04	1464	107	14	EFO_0004587
Disease	disks large homolog 3 measurement	ZFPM1 MEF2D	8.40e-04	12	107	2	EFO_0802472
Disease	monocyte count	ZC3H12A ZNF366 ZFPM1 ZYX MEF2D VSIR RYR1 TLN1 MAST1 HAX1 NEURL1B ARHGAP45 DISP1	9.89e-04	1320	107	13	EFO_0005091
Disease	Connective Tissue Diseases	TPSAB1 ZNF469	9.90e-04	13	107	2	C0009782
Disease	Metastatic melanoma	SCYL1 MAP3K10 MAST1	1.01e-03	54	107	3	C0278883
Disease	alkaline phosphatase measurement	ZNF366 KLF15 IRF5 ZFPM1 ZBTB7A NFATC1 NFATC4 HS6ST1 EXOC3L4 MAMSTR COG5	1.16e-03	1015	107	11	EFO_0004533
Disease	Situs ambiguus	DNAH5 DNAH9	1.33e-03	15	107	2	C0266642
Disease	Amelogenesis imperfecta	AMBN FAM83H	1.71e-03	17	107	2	cv:C0002452
Disease	basophil count	ZFPM1 GMIP ZYX RYR1 EPS15L1 ZNF469 PIK3R2	1.93e-03	483	107	7	EFO_0005090
Disease	Systemic Scleroderma	IRF5 SIRT7	2.14e-03	19	107	2	C0036421
Disease	urticaria	TPSAB1 TPSB2	2.37e-03	20	107	2	EFO_0005531
Disease	eosinophil count	CCDC117 CARMIL2 IRF5 ZFPM1 GMIP KDM6B CBLB NACAD ZBTB7A EPS15L1 PIK3R2 NEURL1B ARHGAP45	2.85e-03	1488	107	13	EFO_0004842
Disease	lymphocyte percentage of leukocytes	ZNF366 GMIP VSIR EPS15L1 NFATC1 HS6ST1 NEURL1B ARHGAP45	2.95e-03	665	107	8	EFO_0007993
Disease	Ovarian Serous Adenocarcinoma	STK36 MAST1	3.14e-03	23	107	2	C1335177
Disease	basophil percentage of granulocytes	ZFPM1 RYR1 ZNF469	3.45e-03	83	107	3	EFO_0007995
Disease	obsolete_red blood cell distribution width	CCDC117 ZC3H12A CARMIL2 ZNF366 RELB BCL11A ZFPM1 VSIR MAST1 TIGD5 NEURL1B COG5	3.55e-03	1347	107	12	EFO_0005192

Protein segments in the cluster

Peptide	Gene	Start	Entry
YRGPEELGAGPESPP	BEND5	41	Q7L4P6
LKGPPPFEDPLAFDG	EVI5L	706	Q96CN4
PDFLGAPGLALPAEP	EXOC3L4	351	Q17RC7
PDPFQPLGADSGDPF	EPS15L1	811	Q9UBC2
AFPPGADGAELAPRP	CCDC117	31	Q8IWD4
ERGAGLSPAAPPDPS	C17orf114	21	A0A1B0GUV1
APFFRDPPAPLGEPG	C4orf33	36	Q8N1A6
LQGDPFGLPSFSPPR	CTF1	51	Q16619
EGGDTALLPEFPRGP	ACOX3	6	O15254
FPDPQGPSLPGLDFA	AMBN	196	Q9NP70
LRPRAGPPGPTDDFS	ADGRB1	156	O14514
PALPAPDGGEPSLLE	CARMIL2	906	Q6F5E8
PGPAGDNPLELSRIP	GPNMB	351	Q14956
AALFLPPDEGPFPGI	ACOT6	146	Q3I5F7
PPDEGPFPGIIDLFG	ACOT6	151	Q3I5F7
DGASALPAAPPGLRP	DLL3	471	Q9NYJ7
GRSPEPDGPAPAFLR	CEP170B	851	Q9Y4F5
DHLPEPDLGDAAPPG	CBY3	6	A6NI87
PELPDFSDPLLGFEP	DISP1	211	Q96F81
LLPPPGAEDPAAGAA	ATP10A	31	O60312
LPDNFRPPGEDFRSP	RBM12B	861	Q8IXT5
DLEDQPRGSPPLPAG	RABL6	446	Q3YEC7
PPAAPELGALGSPDL	RELB	26	Q01201
PSEPREDVLGFLPGP	PALM3	156	A6NDB9
PGLGEGDPRPELVPF	ARHGEF17	1621	Q96PE2
PRGGPADPVDYLPAA	PARD3B	1086	Q8TEW8
GPGPRDLLDFPRLPD	MAP3K10	846	Q02779
GDPESPRPPALDDAF	HAX1	251	O00165
EPAFPPLGSLPEPDF	HELT	131	A6NFD8
DGADAVFPGPSLEPP	ARHGAP45	36	Q92619
PSPFELLEPPTSGGF	MAP1S	221	Q66K74
ADPGRDPLLAFAPRP	LZTS3	11	O60299
GPLPPRLDENSAEPG	GMIP	386	Q9P107
GELPARGPRLFDFPP	KDM6B	661	O15054
RGPRLFDFPPTPLED	KDM6B	666	O15054
ASGLAEGRFPPTPPL	BCL11A	251	Q9H165
IPPLGEDAFDALPPS	CBLB	806	Q13191
PAGPFPEGAEPGVLE	PDX1	96	P52945
PGALPGPIRPLSEDD	PDZD2	986	O15018
LAPARSPGPAADGPI	ZFPM1	781	Q8IX07
DLGSPPPPADFAPED	NFATC1	356	O95644
PDPEERPGAEGAPLL	ACBD3	21	Q9H3P7
LPDSFPRGECPKPGA	EGR4	51	Q05215
APPPGNPAGFRELLS	IRF5	201	Q13568
FPLLGPQGAPPFLEE	INSM2	26	Q96T92
GGRAPPDDLDLFPTP	HS6ST1	46	O60243
GADPLLPEGASRPPV	MAST1	1341	Q9Y2H9
DGPPTPASLRFDGSP	PCF11	781	O94913
RDGAPEPGLTLPDLP	PIK3R2	101	O00459
FPPGGRNPPSSDELD	COG5	501	Q9UP83
PDLPFTALPPGASDG	FZD7	186	O75084
RGGPPAAADPFGPLL	GAK	951	O14976
LEDPAGSPLEPGPSL	IL37	26	Q9NZH6
DPDEGLFGPGRKLSP	HS1BP3	236	Q53T59
FFSPAPDPRALLGGP	PRMT7	651	Q9NVM4
LPAPPGVTPDDLDAF	CC2D1B	711	Q5T0F9
SPGRFPEALDELPLP	ANKRD9	291	Q96BM1
SEAEGPLDAPRPGPA	FBXO41	496	Q8TF61
DDPLPPIPLDFPGSF	MAMSTR	321	Q6ZN01
CLPEFPLGDPDDVPR	KLF15	121	Q9UIH9
PGEPGPPSDAVFARD	IGFN1	826	Q86VF2
LFFLRTGPEPPGPDS	DNAH9	101	Q9NYC9
PPPREEGLGFPSFLD	FAM83H	331	Q6ZRV2
LGFSPPALPPERDSG	GTF2IRD1	661	Q9UHL9
DGLGLSPKPPAPDFA	PRDM13	186	Q9H4Q3
ERGPEAPPSALPAGA	RYR1	3286	P21817
PGEPALDSDGPGRPY	EPB41L3	551	Q9Y2J2
LELPPPAGPGDTAFD	DNAH5	2516	Q8TE73
PGLSGEDTIPDPPRL	LRRN4	571	Q8WUT4
ELANFDPSRPGPPSG	LSR	411	Q86X29
PAVFPAARPEPGDGL	MEF2D	456	Q14814
DSPFGTLPGSAEPPL	RTN4R	381	Q9BZR6
PGAPEGIPSPELFSD	USH2A	2621	O75445
GDVDNDERLPPPFPL	TPSAB1	161	Q15661
GDVDNDERLPPPFPL	TPSB2	161	P20231
SPGPFFDPEFRLLEP	PRR23A	211	A6NEV1
DFPFELIPEPPEGGL	SCYL1	11	Q96KG9
GRDLSGFPAPPGEEP	NFATC4	886	Q14934
PTPPPGGKDREAFEA	PIM2	16	Q9P1W9
GPEPRAAPSLEDPAG	PRR23B	36	Q6ZRT6
GLDDPSPAEPGAPAL	MEX3C	56	Q5U5Q3
PGPPLDFLERFPAST	SLC52A2	181	Q9HAB3
PAGDLAPALAEDGPP	WIZ	1286	O95785
EAPPGDRGAPLSSAP	SIRT7	366	Q9NRC8
RSLEPPLFPPDLFGE	ARHGAP4	586	P98171
GPDLGTPFTSRLPPE	STK36	266	Q9NRP7
GDAGPAAFVELPLPP	PRR22	161	Q8IZ63
RPAGPDPLDPTDLNG	VPS51	51	Q9UID3
GPLDPASAADGLPRP	SEMA6B	806	Q9H3T3
ESPGDPGTASPRPLF	YIPF6	6	Q96EC8
PPDDPLGRHGPSLDN	ZC3H12A	276	Q5D1E8
LAAPDLGDFPPAGRG	ZCCHC3	81	Q9NUD5
PFLVPEPEAGGTRAP	ZFHX2	1551	Q9C0A1
PPSLAEDPAVGGPRA	SLC16A13	191	Q7RTY0
IPEAPAGPPSDFGLF	TLN1	36	Q9Y490
SPGLEGPLASPPARD	RNF44	36	Q7L0R7
LSPPGPGDVFFPSLD	VSIR	286	Q9H7M9
LAPLPPRDPNGAGSE	ZNF747	16	Q9BV97
LALGRAPGPPPADAA	NEURL1B	241	A8MQ27
PPDDPLGRHGPSLEN	ZC3H12B	331	Q5HYM0
CFLGPFEDPVGLPGP	ZNF469	3031	Q96JG9
RYEPPPGDLDGFPGV	ZNF366	56	Q8N895
PLGSPLSREEGEAPP	TOPORS	6	Q9NS56
FPLPPPPLAGDGDDA	ZYX	71	Q15942
SDPDPPAPLAEGAFL	ZNF687	351	Q8N1G0
LFAGDPGLGPEEPRA	STRCP1	1491	A6NGW2
GLPTPERSPLDGLEP	SOX18	211	P35713
DGLEPGEAAFFPPPA	SOX18	221	P35713
PPDDPLGRHGPSLDN	ZC3H12C	386	Q9C0D7
GPPFPPDHREFSEGD	WDR33	1051	Q9C0J8
EPALPSGAGPLPDRA	TIGD5	206	Q53EQ6
ERDEDAPTGGLFPPP	ZBTB7A	246	O95365
FGPPAPAPRDGGADL	ZFTA	656	C9JLR9
VDRPLGPDPSAPGTL	NACAD	1221	O15069