Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G-protein beta/gamma-subunit complex binding	GNAS GNA14	3.42e-04	25	22	2	GO:0031683
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNAS GNA14	6.16e-04	35	22	2	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNAS GNA14	8.46e-04	41	22	2	GO:1905360
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	RNF31 GNAS GNA14	9.28e-04	185	22	3	GO:0009898
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNAS GNA14	1.57e-03	56	22	2	GO:0031234
GeneOntologyCellularComponent	cytoplasmic side of membrane	RNF31 GNAS GNA14	1.73e-03	230	22	3	GO:0098562
GeneOntologyCellularComponent	side of membrane	RNF31 BTNL8 ADGRA3 GNAS GNA14	1.85e-03	875	22	5	GO:0098552
GeneOntologyCellularComponent	Golgi cisterna membrane	GAL3ST3 GOLGA8H	4.36e-03	94	22	2	GO:0032580
Domain	SPIN-2	SPIN2B SPIN2A	1.32e-06	2	22	2	IPR029564
Domain	Spin-Ssty	SPIN2B SPIN2A	1.32e-05	5	22	2	PF02513
Domain	SPIN/Ssty	SPIN2B SPIN2A	1.32e-05	5	22	2	IPR003671
Domain	G-alpha	GNAS GNA14	1.57e-04	16	22	2	PF00503
Domain	GproteinA_insert	GNAS GNA14	1.57e-04	16	22	2	IPR011025
Domain	G_alpha	GNAS GNA14	1.57e-04	16	22	2	SM00275
Domain	-	GNAS GNA14	1.57e-04	16	22	2	1.10.400.10
Domain	Gprotein_alpha_su	GNAS GNA14	1.78e-04	17	22	2	IPR001019
Domain	GPS	ADGRA3 PKD1L1	8.14e-04	36	22	2	PS50221
Domain	GPS	ADGRA3 PKD1L1	8.60e-04	37	22	2	IPR000203
Domain	-	GAL3ST3 DHX34 GNAS GNA14	1.04e-02	746	22	4	3.40.50.300
Domain	P-loop_NTPase	GAL3ST3 DHX34 GNAS GNA14	1.61e-02	848	22	4	IPR027417
Pubmed	Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.	SPIN2B SPIN2A	3.82e-07	2	22	2	12145692
Pubmed	A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.	SPIN2B SPIN2A	5.72e-06	6	22	2	29061846
Pubmed	CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.	TRAF3IP1 CUL1	8.01e-06	7	22	2	31754404
Pubmed	Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.	GNAS GNA14	1.71e-05	10	22	2	8588930
Pubmed	Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.	CUL1 EIF3A	2.51e-05	12	22	2	20399188
Pubmed	Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.	GNAS GNA14	2.51e-05	12	22	2	2508088
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	CUL1 MVP FAM120C GNAS GNA14	2.68e-05	582	22	5	20467437
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNAS GNA14	1.43e-04	28	22	2	8858601
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	CUL1 MVP EIF3A ADGRA3 GNAS	2.68e-04	949	22	5	36574265
Pubmed	Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.	DHX34 EIF3A	3.09e-04	41	22	2	8590280
Pubmed	Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation.	MVP EIF3A	3.24e-04	42	22	2	34581821
Pubmed	Evolution of the mammalian G protein alpha subunit multigene family.	GNAS GNA14	4.41e-04	49	22	2	1302014
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	MVP EIF3A PPAN GNAS	5.50e-04	615	22	4	31048545
Pubmed	EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability.	MVP EIF3A	5.56e-04	55	22	2	32269044
Cytoband	Xp11.1	SPIN2B SPIN2A	1.31e-06	4	22	2	Xp11.1
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	SPIN2B SPIN2A FAM120C	7.53e-04	377	22	3	chrXp11
GeneFamily	Tudor domain containing\|Spindlin family	SPIN2B SPIN2A	5.56e-06	5	14	2	1089
GeneFamily	Tudor domain containing	SPIN2B SPIN2A	3.65e-04	37	14	2	780
Drug	lithium indium	SPIN2B SPIN2A	8.91e-07	2	22	2	CID011116062
Drug	rubidium nitrate	SPIN2B SPIN2A	8.91e-07	2	22	2	CID000025731
Drug	scandium phosphate	SPIN2B SPIN2A	8.91e-07	2	22	2	CID006365269
Drug	diphenylketen	SPIN2B SPIN2A	5.34e-06	4	22	2	CID000013696
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A	TRAF3IP1 DHX34 PRSS12 GNA14	3.59e-05	198	22	4	4062_DN

Protein segments in the cluster

Peptide	Gene	Start	Entry
ARQCVWGHNKERGRR	PI16	71	Q6UXB8
DGGHNKRWRVGVCRD	BTNL8	346	Q6UX41
QDERKAWRRCDRGGF	ADGRA3	391	Q8IWK6
SRRQWGRHDCSHRED	PRSS12	466	P56730
DRDRRRVKNGEHSWD	TRAF3IP1	276	Q8TDR0
LRARKECWDRDGKER	MVP	176	Q14764
WRHVARAGRACVERE	GAL3ST3	306	Q96A11
KEWRRGEGRDEDRSH	EIF3A	916	Q14152
NRHWVRRECDEGRKG	CUL1	141	Q13616
GKDRLAEWGRRCQAE	FAM120C	176	Q9NX05
RLGWEDCRDSRVREK	MTFMT	31	Q96DP5
CAEHLKGERARWQQR	GOLGA8H	241	P0CJ92
RNSRKWCRRRGIEEH	DHX34	661	Q14147
QCWLSAGRHDGRVER	PKD1L1	1896	Q8TDX9
CEQHVRWGRFAKGRG	GARIN3	96	Q8TC56
DVGGQRSERRKWIHC	GNA14	201	O95837
DVGGQRDERRKWIQC	GNAS	866	Q5JWF2
RRNIVGCRISHGWKE	SPIN2A	46	Q99865
VRCKRQWEEQHRGRS	RNF31	826	Q96EP0
RWEMDRGRGRLCDQK	PPAN	421	Q9NQ55
RRNIVGCRISHGWKE	SPIN2B	46	Q9BPZ2
RKKWRRQGAHSECEE	SPOCD1	206	Q6ZMY3