Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

8.19e-07125827GO:0015108
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRD GABRR3 GABRA4 GABRA6

9.77e-0719824GO:0004890
GeneOntologyMolecularFunctionGABA receptor activity

GABRD GABRR3 GABRA4 GABRA6

1.83e-0622824GO:0016917
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

2.91e-06151827GO:0008509
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A6 SLC12A4 SLC12A7

5.51e-069823GO:0015379
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

6.62e-06171827GO:0015103
GeneOntologyMolecularFunctionammonium channel activity

SLC12A6 SLC12A4 SLC12A7

1.43e-0512823GO:0008519
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRR3 GABRA4 GABRA6

5.21e-0518823GO:0022851
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH6 DYNC1H1

5.21e-0518823GO:0008569
GeneOntologyMolecularFunctionchannel activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7 GABRR3 GABRA4 GABRA6

5.68e-055258210GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7 GABRR3 GABRA4 GABRA6

5.77e-055268210GO:0022803
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7

6.48e-05167826GO:0015079
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A6 SLC12A4 SLC12A7

1.11e-0423823GO:0015377
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRD GABRR3 GABRA4 GABRA6

1.48e-0465824GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRD GABRR3 GABRA4 GABRA6

1.48e-0465824GO:0022824
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A6 SLC12A4 SLC12A7

1.62e-0426823GO:0015296
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH6 DYNC1H1

2.03e-0428823GO:0051959
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6

2.64e-047588211GO:0015318
GeneOntologyMolecularFunctionpolysaccharide binding

CLEC18A CLEC18B CLEC18C

2.76e-0431823GO:0030247
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRD GABRR3 GABRA4 GABRA6

2.85e-0477824GO:0005230
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6

3.87e-047938211GO:0015075
GeneOntologyMolecularFunctionchloride channel activity

GABRD GABRR3 GABRA4 GABRA6

4.34e-0486824GO:0005254
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH6 DYNC1H1

4.69e-0437823GO:0045505
GeneOntologyMolecularFunctiontransporter activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 ATG2B KCNAB2 PEX13 ATP8B1 SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6

7.15e-0412898214GO:0005215
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRD GABRR3 GABRA4 GABRA6

7.68e-04100824GO:0030594
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRD GABRR3 GABRA4 GABRA6

8.58e-04103824GO:0005253
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRA4 GABRA6

8.94e-0411822GO:0008503
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRR3 GABRA4 GABRA6

1.14e-0350823GO:0099095
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A6 SLC12A4 SLC12A7 SLC29A1

1.47e-03119824GO:0015294
GeneOntologyMolecularFunctioncardiolipin binding

IRGM ATP8B1

1.47e-0314822GO:1901612
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRD GABRA4 GABRA6

1.66e-0357823GO:1904315
GeneOntologyMolecularFunction5'-nucleotidase activity

NT5DC4 NT5C2

1.69e-0315822GO:0008253
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRD GABRA4 GABRA6

1.93e-0360823GO:0099529
GeneOntologyMolecularFunctionnucleotidase activity

NT5DC4 NT5C2

2.44e-0318822GO:0008252
GeneOntologyMolecularFunctionphosphatidylglycerol binding

IRGM ATP8B1

2.44e-0318822GO:1901611
GeneOntologyMolecularFunctiongated channel activity

GABRD KCNH1 KCNAB2 GABRR3 GABRA4 GABRA6

2.52e-03334826GO:0022836
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRD SLC9C1 KCNH1 KCNAB2 GABRR3 GABRA4 GABRA6

2.80e-03459827GO:0005216
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH2 DNAH6 DYNC1H1

3.00e-0370823GO:0003777
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7 SLC29A1

3.00e-03465827GO:0046873
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 PEX13 SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6

3.07e-0311808212GO:0022857
GeneOntologyMolecularFunctionsymporter activity

SLC12A6 SLC12A4 SLC12A7 SLC29A1

3.40e-03150824GO:0015293
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRD GABRA4 GABRA6

3.64e-0375823GO:0098960
GeneOntologyBiologicalProcesschloride transport

GABRD SLC12A6 SLC12A4 ATP8B1 SLC12A7 GABRR3 GABRA4 GABRA6

3.52e-08128808GO:0006821
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A6 SLC12A4 SLC12A7

2.24e-074803GO:0140157
GeneOntologyBiologicalProcesschloride transmembrane transport

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

2.64e-07112807GO:1902476
GeneOntologyBiologicalProcessinorganic anion transport

GABRD SLC12A6 SLC12A4 ATP8B1 SLC12A7 GABRR3 GABRA4 GABRA6

4.88e-07180808GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

GABRD SLC12A6 SLC12A4 ATP8B1 SLC12A7 GABRR3 GABRA4 GABRA6

5.54e-07183808GO:0006820
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

8.93e-07134807GO:0098661
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRD SLC12A6 SLC12A4 SLC12A7 GABRR3 GABRA4 GABRA6

2.17e-06153807GO:0098656
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRD GABRR3 GABRA4 GABRA6

1.00e-0535804GO:0007214
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GABRD SLC12A6 MYOF SLC12A4 KCNH1 SQSTM1 CBLN2 VPS13A SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6 RASD2

1.24e-059318014GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GABRD SLC12A6 MYOF SLC12A4 KCNH1 SQSTM1 CBLN2 VPS13A SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6 RASD2

1.24e-059318014GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

GABRD SLC12A6 MYOF SLC12A4 KCNH1 SQSTM1 CBLN2 VPS13A SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6 RASD2

1.36e-059398014GO:0099537
GeneOntologyBiologicalProcessammonium transmembrane transport

SLC12A6 SLC12A4 SLC12A7

1.56e-0513803GO:0072488
GeneOntologyBiologicalProcesssynaptic signaling

GABRD SLC12A6 MYOF SLC12A4 KCNH1 SQSTM1 CBLN2 VPS13A SLC12A7 SLC29A1 GABRR3 GABRA4 GABRA6 RASD2

2.10e-059768014GO:0099536
GeneOntologyBiologicalProcesschloride ion homeostasis

SLC12A6 SLC12A4 SLC12A7

1.22e-0425803GO:0055064
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

SLC12A6 SLC12A4 SLC12A7

1.72e-0428803GO:0055081
GeneOntologyBiologicalProcessprotein targeting to vacuole involved in autophagy

IRGM SQSTM1

2.21e-046802GO:0071211
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 SLC12A7

2.85e-04232806GO:0071805
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 CHD7 ATP8B1 SLC12A7 GABRR3 PLCE1 GABRA4 GABRA6

3.38e-0411158013GO:0034220
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A6 SLC12A4 SLC12A7

3.97e-0437803GO:0055075
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GABRD SLC12A6 SLC9C1 SLC12A4 KCNH1 KCNAB2 CHD7 SLC12A7 GABRR3 PLCE1 GABRA4 GABRA6

5.26e-0410178012GO:0098660
GeneOntologyCellularComponentGABA-A receptor complex

GABRD GABRR3 GABRA4 GABRA6

7.76e-0719814GO:1902711
GeneOntologyCellularComponentGABA receptor complex

GABRD GABRR3 GABRA4 GABRA6

1.19e-0621814GO:1902710
GeneOntologyCellularComponentchloride channel complex

GABRD GABRR3 GABRA4 GABRA6

7.07e-0557814GO:0034707
GeneOntologyCellularComponenttransporter complex

GABRD KCNH1 KCNAB2 OLFM1 PEX13 ATP8B1 GABRR3 GABRA4 GABRA6

2.74e-04550819GO:1990351
GeneOntologyCellularComponentinner dynein arm

DNAH2 DNAH6

6.54e-0410812GO:0036156
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRD KCNH1 KCNAB2 OLFM1 GABRR3 GABRA4 GABRA6

6.60e-04378817GO:0034702
GeneOntologyCellularComponentpostsynaptic membrane

GABRD KCNH1 KCNAB2 OLFM1 GABRR3 GABRA4 GABRA6

9.87e-04405817GO:0045211
GeneOntologyCellularComponentpostsynaptic specialization membrane

KCNH1 KCNAB2 OLFM1 GABRA4 GABRA6

1.11e-03201815GO:0099634
GeneOntologyCellularComponentdynein complex

DNAH2 DNAH6 DYNC1H1

1.21e-0354813GO:0030286
GeneOntologyCellularComponentleading edge membrane

KCNH1 INPP5K IFIT5 GABRA4 GABRA6

1.35e-03210815GO:0031256
GeneOntologyCellularComponentcell projection membrane

SLC9C1 KCNH1 INPP5K IFIT5 ATP8B1 GABRA4 GABRA6

1.41e-03431817GO:0031253
DomainKCL_cotranspt

SLC12A6 SLC12A4 SLC12A7

3.02e-074803IPR000076
DomainNUT

NUTM1 NUTM2F NUTM2G

7.52e-075803IPR024310
DomainNUT_N

NUTM1 NUTM2F NUTM2G

7.52e-075803IPR024309
DomainNUT

NUTM1 NUTM2F NUTM2G

7.52e-075803PF12881
DomainGABAA/Glycine_rcpt

GABRD GABRR3 GABRA4 GABRA6

2.60e-0623804IPR006028
DomainSLC12A_fam

SLC12A6 SLC12A4 SLC12A7

2.62e-067803IPR004842
DomainSLC12_C

SLC12A6 SLC12A4 SLC12A7

4.17e-068803IPR018491
DomainSLC12

SLC12A6 SLC12A4 SLC12A7

4.17e-068803PF03522
DomainKCC1

SLC12A6 SLC12A4

1.81e-052802IPR000622
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH6 DYNC1H1

2.66e-0514803IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH6 DYNC1H1

2.66e-0514803IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH6 DYNC1H1

2.66e-0514803IPR013602
DomainDHC_N2

DNAH2 DNAH6 DYNC1H1

2.66e-0514803PF08393
DomainMT

DNAH2 DNAH6 DYNC1H1

2.66e-0514803PF12777
DomainAAA_8

DNAH2 DNAH6 DYNC1H1

2.66e-0514803PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH6 DYNC1H1

2.66e-0514803IPR011704
DomainAAA_5

DNAH2 DNAH6 DYNC1H1

2.66e-0514803PF07728
DomainDHC_fam

DNAH2 DNAH6 DYNC1H1

3.32e-0515803IPR026983
Domain-

CLEC18A CLEC18B CLEC18C

3.32e-05158033.40.33.10
DomainDynein_heavy_dom

DNAH2 DNAH6 DYNC1H1

3.32e-0515803IPR004273
DomainCAP

CLEC18A CLEC18B CLEC18C

3.32e-0515803PF00188
DomainCAP_domain

CLEC18A CLEC18B CLEC18C

3.32e-0515803IPR014044
DomainSCP

CLEC18A CLEC18B CLEC18C

3.32e-0515803SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18B CLEC18C

3.32e-0515803IPR001283
DomainDynein_heavy

DNAH2 DNAH6 DYNC1H1

3.32e-0515803PF03028
DomainNeurotransmitter_ion_chnl_CS

GABRD GABRR3 GABRA4 GABRA6

4.07e-0545804IPR018000
DomainNeur_chan_memb

GABRD GABRR3 GABRA4 GABRA6

4.44e-0546804PF02932
DomainNeur_chan_LBD

GABRD GABRR3 GABRA4 GABRA6

4.84e-0547804PF02931
DomainNEUROTR_ION_CHANNEL

GABRD GABRR3 GABRA4 GABRA6

4.84e-0547804PS00236
DomainNeurotrans-gated_channel_TM

GABRD GABRR3 GABRA4 GABRA6

4.84e-0547804IPR006029
Domain-

GABRD GABRR3 GABRA4 GABRA6

4.84e-05478042.70.170.10
DomainNeur_channel

GABRD GABRR3 GABRA4 GABRA6

4.84e-0547804IPR006201
DomainNeur_chan_lig-bd

GABRD GABRR3 GABRA4 GABRA6

4.84e-0547804IPR006202
DomainAA-permease/SLC12A_dom

SLC12A6 SLC12A4 SLC12A7

1.10e-0422803IPR004841
DomainAA_permease

SLC12A6 SLC12A4 SLC12A7

1.10e-0422803PF00324
DomainATG_C

ATG2B VPS13A

1.80e-045802PF09333
DomainAutophagy-rel_C

ATG2B VPS13A

1.80e-045802IPR015412
DomainBRK

SMARCA2 CHD7

2.69e-046802SM00592
DomainBRK_domain

SMARCA2 CHD7

2.69e-046802IPR006576
DomainGABAAa_rcpt

GABRA4 GABRA6

2.69e-046802IPR001390
DomainBRK

SMARCA2 CHD7

2.69e-046802PF07533
DomainCNMP_BINDING_1

SLC9C1 KCNH1 CNBD2

3.43e-0432803PS00888
DomainCNMP_BINDING_2

SLC9C1 KCNH1 CNBD2

3.43e-0432803PS00889
DomaincNMP

SLC9C1 KCNH1 CNBD2

4.11e-0434803SM00100
DomaincNMP_binding

SLC9C1 KCNH1 CNBD2

4.11e-0434803PF00027
DomaincNMP-bd_dom

SLC9C1 KCNH1 CNBD2

4.49e-0435803IPR000595
DomainCNMP_BINDING_3

SLC9C1 KCNH1 CNBD2

4.49e-0435803PS50042
DomainVPS13_N

ATG2B VPS13A

4.99e-048802IPR026854
DomainChorein_N

ATG2B VPS13A

4.99e-048802PF12624
DomainDHC_N1

DNAH2 DYNC1H1

4.99e-048802PF08385
DomainDynein_heavy_dom-1

DNAH2 DYNC1H1

4.99e-048802IPR013594
DomaincNMP-bd-like

SLC9C1 KCNH1 CNBD2

5.73e-0438803IPR018490
DomainBTB

LZTR1 KCTD19 KLHL15 ZBTB14 KLHL17

6.21e-04160805PS50097
DomainC-type_lectin_CS

CLEC18A CLEC18B CLEC18C

8.25e-0443803IPR018378
Domain-

SLC9C1 KCNH1 CNBD2

1.14e-03488032.60.120.10
DomainSKP1/BTB/POZ

LZTR1 KCTD19 KLHL15 ZBTB14 KLHL17

1.31e-03189805IPR011333
DomainRmlC-like_jellyroll

SLC9C1 KCNH1 CNBD2

1.36e-0351803IPR014710
DomainSEA

TMPRSS11F IMPG2

1.59e-0314802SM00200
Domain-

TMPRSS11F IMPG2

1.83e-03158023.30.70.960
DomainKelch

LZTR1 KLHL15 KLHL17

1.97e-0358803SM00612
DomainBTB

LZTR1 KLHL15 ZBTB14 KLHL17

2.42e-03131804PF00651
DomainKelch_1

LZTR1 KLHL15 KLHL17

3.37e-0370803PF01344
DomainKelch_1

LZTR1 KLHL15 KLHL17

3.37e-0370803IPR006652
DomainAAA+_ATPase

ORC1 DNAH2 DNAH6 DYNC1H1

3.41e-03144804IPR003593
DomainAAA

ORC1 DNAH2 DNAH6 DYNC1H1

3.41e-03144804SM00382
DomainSEA

TMPRSS11F IMPG2

3.96e-0322802PF01390
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A4 SLC12A7

2.17e-067573M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A4 SLC12A7

2.17e-067573MM15081
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRD GABRA4 GABRA6

2.60e-0431573M39369
PathwayREACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY

MLXIPL PRKAG2

4.43e-048572M26990
PathwayWP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION

GABRD GABRA4 GABRA6

4.78e-0438573M39854
PathwayBIOCARTA_FLUMAZENIL_PATHWAY

GABRA4 GABRA6

5.68e-049572M22034
PathwayBIOCARTA_GABA_PATHWAY

GABRA4 GABRA6

7.08e-0410572M477
PathwayKEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_HYPOXANTHINE_GUANINE_TO_IMP_GMP

NT5DC4 NT5C2

8.63e-0411572M47820
PathwayKEGG_MEDICUS_REFERENCE_PURINE_SALVAGE_PATHWAY_ADENINE_TO_AMP

NT5DC4 NT5C2

8.63e-0411572M47819
PathwayREACTOME_RIBAVIRIN_ADME

NT5C2 SLC29A1

8.63e-0411572M46429
PathwayREACTOME_RIBAVIRIN_ADME

NT5C2 SLC29A1

1.03e-0312572MM16638
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18B CLEC18C

1.26e-08382326170455
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18B CLEC18C

1.26e-08382316336259
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18B CLEC18C

1.26e-08382333603190
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A6 SLC12A4 SLC12A7

1.26e-08382311551954
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A6 SLC12A4 SLC12A7

1.26e-08382315262997
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A6 SLC12A4 SLC12A7

1.26e-08382321733850
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18A CLEC18B CLEC18C

5.04e-08482316709836
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A6 SLC12A4 SLC12A7

5.04e-08482312637262
Pubmed

ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

SQSTM1 KCNAB2 GABRR3

1.26e-07582312431995
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A6 SLC12A4 SLC12A7

7.01e-07882311395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A6 SLC12A4 SLC12A7

7.01e-07882324393035
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A6 SLC12A4 SLC12A7

7.01e-07882321613606
Pubmed

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

SLC12A6 SLC12A4 SLC12A7

7.01e-07882312386165
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A6 SLC12A4 SLC12A7

1.05e-06982319323993
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SLC12A6 SLC12A4 OSBPL1A ATG2B VPS13A PEX13 SLC12A7 SLC29A1 MFF

3.01e-0650482934432599
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH6 DYNC1H1

4.51e-06148239373155
Pubmed

Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants.

GABRD GABRA4

5.49e-06282224431441
Pubmed

Altered markers of tonic inhibition in the dorsolateral prefrontal cortex of subjects with schizophrenia.

GABRD GABRA4

5.49e-06282219289452
Pubmed

A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.

GABRD GABRA4

5.49e-06282220299596
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A6 SLC12A4

5.49e-06282234031912
Pubmed

A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol.

GABRD GABRA4

5.49e-06282217159992
Pubmed

SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus.

SLC12A6 SLC12A7

5.49e-06282231393094
Pubmed

Profound desensitization by ambient GABA limits activation of δ-containing GABAA receptors during spillover.

GABRD GABRA6

5.49e-06282221228184
Pubmed

Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors.

GABRD GABRA4

5.49e-06282224778259
Pubmed

RIPosomes are targets of IRGM-SQSTM1-dependent autophagy.

IRGM SQSTM1

5.49e-06282236628446
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A6 SLC12A4

5.49e-06282217510708
Pubmed

Gamma-aminobutyric acid (GABA) receptors genes polymorphisms and risk for restless legs syndrome.

GABRR3 GABRA4

5.49e-06282229720720
Pubmed

α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).

GABRD GABRA4

5.49e-06282222753476
Pubmed

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.

SLC12A6 SLC12A7

5.49e-06282210347194
Pubmed

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

SLC12A6 SLC12A4

5.49e-06282231835175
Pubmed

A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells.

NOC3L PLCE1

5.49e-06282211146508
Pubmed

Ketamine, but not phencyclidine, selectively modulates cerebellar GABA(A) receptors containing alpha6 and delta subunits.

GABRD GABRA6

5.49e-06282218480294
Pubmed

α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells.

GABRD GABRA6

5.49e-06282226134650
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRR3 GABRA4 GABRA6

1.00e-051882319078961
Pubmed

Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.

GABRD GABRA4 GABRA6

1.63e-052182325708312
Pubmed

Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells.

GABRD GABRA6

1.64e-05382211136737
Pubmed

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

SLC12A6 SLC12A4

1.64e-05382231352162
Pubmed

Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines.

GABRD GABRA4

1.64e-05382227136678
Pubmed

IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness.

SLC12A6 SLC12A7

1.64e-05382217133354
Pubmed

Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.

SQSTM1 MFF

1.64e-05382226008206
Pubmed

Spatiotemporal specificity of GABAA receptor-mediated regulation of adult hippocampal neurogenesis.

GABRD GABRA4

1.64e-05382221722213
Pubmed

Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.

SLC12A6 SLC12A4

1.64e-05382235274823
Pubmed

Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.

SLC12A6 GABRA6

1.64e-05382222252133
Pubmed

Assembly rules for GABAA receptor complexes in the brain.

GABRD GABRA6

1.64e-05382228816653
Pubmed

Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells.

NT5C2 SLC29A1

1.64e-05382219428333
Pubmed

Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney.

SLC12A6 SLC12A7

1.64e-05382224089410
Pubmed

Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus.

GABRD GABRA4

1.64e-05382224027285
Pubmed

Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters.

SLC12A6 SLC12A7

1.64e-05382212657561
Pubmed

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

SLC12A6 SLC12A4 SLC12A7

1.88e-052282318391953
Pubmed

p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.

IRGM SQSTM1

3.28e-05482226440898
Pubmed

Differential assembly diversifies GABAA receptor structures and signalling.

GABRD GABRA4

3.28e-05482235355020
Pubmed

Ectopic Expression of α6 and δ GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus.

GABRD GABRA6

3.28e-05482226658866
Pubmed

GABAA Receptors and the Diversity in their Structure and Pharmacology.

GABRD GABRA6

3.28e-05482228528665
Pubmed

Genetic association of PLCE1, C11orf92-C11orf93, and NOC3L with colorectal cancer risk in the Han population.

NOC3L PLCE1

3.28e-05482224146276
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GABRD GABRR3 GABRA4 GABRA6

4.16e-058182422723691
Pubmed

GABAA receptors: structure, function, pharmacology, and related disorders.

GABRD GABRA6

5.47e-05582234417930
Pubmed

A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

NOC3L PLCE1

5.47e-05582220729852
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

MYOF CUEDC2 RRP12 NOC3L NT5C2 IFIT5 PLCE1

5.77e-0541582716385451
Pubmed

GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice.

GABRA4 GABRA6

8.19e-05682220457185
Pubmed

GABA(A) receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice.

GABRD GABRA6

8.19e-05682220412381
Pubmed

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.

IRGM SQSTM1

8.19e-05682221757726
Pubmed

Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.

IRGM SQSTM1

8.19e-05682232715615
Pubmed

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.

THOP1 SQSTM1 ATG2B MFF

9.11e-059982431723608
Pubmed

Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.

CLEC18A CLEC18B CLEC18C

9.26e-053782322432025
Pubmed

Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.

GABRD GABRA6

1.14e-04782217021187
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK5 MYOF ANAPC1 RRP12 SMARCA2

1.19e-0420282533005030
Pubmed

ATM functions at the peroxisome to induce pexophagy in response to ROS.

SQSTM1 PEX13

1.52e-04882226344566
Pubmed

The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.

IRGM SQSTM1

1.52e-04882230612879
Pubmed

gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties.

GABRA4 GABRA6

1.52e-0488228175718
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

ORC1 LZTR1 SQSTM1 VPS13A NUTM2D CLDN34 CHD7 KDM4E NUTM2F MTRF1L NUTM2G

1.58e-041242821130973865
Pubmed

The DNA sequence and comparative analysis of human chromosome 10.

MYOF CUEDC2 RRP12 NOC3L NUTM2D PLCE1

1.69e-0434582615164054
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH2 DNAH6 DYNC1H1

1.90e-04478238812413
Pubmed

Smad2 protein disruption in the central nervous system leads to aberrant cerebellar development and early postnatal ataxia in mice.

GABRD GABRA6

1.96e-04982221464123
Pubmed

Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.

IRGM SQSTM1

1.96e-04982236221902
Pubmed

Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.

SLC12A6 SLC12A7

1.96e-04982214532115
Pubmed

Dynein and kinesin regulate stress-granule and P-body dynamics.

DNAH2 DYNC1H1

2.44e-041082219825938
Pubmed

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

GABRD GABRA4

2.44e-041082221789198
Pubmed

Genetical genomic determinants of alcohol consumption in rats and humans.

GABRD SLC29A1 GABRA4 GABRA6

2.60e-0413082419874574
Pubmed

Review: Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis.

GABRA4 GABRA6

2.98e-04118229924185
Pubmed

Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.

GABRD GABRA4

2.98e-041182238894703
Pubmed

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

ADGRA2 DYNC1H1

2.98e-041182219448619
Pubmed

Protein Binder Toolbox for Studies of Solute Carrier Transporters.

SLC12A6 SLC12A4 SLC12A7

3.20e-045682338878854
Pubmed

Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

SLC12A6 SLC12A4

3.57e-041282227782176
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

MYOF SQSTM1 ATG2B IFIT5 DYNC1H1

3.57e-0425682533397691
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

THOP1 SQSTM1 DNAH2 DYNC1H1

3.64e-0414282430809309
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

MYOF SQSTM1 RRP12 DYNC1H1

3.84e-0414482435681168
Pubmed

Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.

GABRA4 GABRA6

4.21e-041382222569571
Pubmed

Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning.

GABRA4 GABRA6

4.21e-041382222640814
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

MYOF SQSTM1 ATG2B IFIT5 DYNC1H1

4.40e-0426882533024031
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK5 PTBP3 ANAPC1 SMARCA2 CHD7 USP39 DYNC1H1

4.56e-0458282720467437
Pubmed

A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.

SLC12A6 SQSTM1

7.30e-041782220808911
Pubmed

Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development.

CBLN2 SMARCA2

7.30e-041782219135992
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

GREB1L ORC1 MYOF IFRD1 ANAPC1 SQSTM1 RRP12 NOC3L SMARCA2 CHD7 MFF

7.67e-041497821131527615
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

LZTR1 SLC12A4 MTUS1 KLHL15 RRP12 NOC3L VPS13A SLC12A7 SLC29A1

8.15e-04104982927880917
Pubmed

GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.

GABRD GABRA4

8.20e-041882218985723
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

DOCK5 SLC12A6 MYOF SLC12A4 MGST1 VPS13A PEX13 ATP8B1 SLC12A7

8.83e-04106182933845483
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

LZTR1 KLHL15 KLHL17

1.16e-038782337495603
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ORC1 MYOF LZTR1 SLC12A4 RRP12 ADGRA2 DYNC1H1 KLHL17 RASD2

1.17e-03110582935748872
Pubmed

The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.

ORC1 PHKG2 LZTR1 KCTD19

1.28e-0319982436688959
Pubmed

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.

PRKAG2 PLCE1

1.35e-03238229730685
Cytoband16q22.1

CLEC18A SLC12A4 KCTD19 CLEC18C CES4A

1.70e-0611082516q22.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

CLEC18A SLC12A4 KCTD19 CLEC18C CES4A

2.03e-05183825chr16q22
CytobandEnsembl 112 genes in cytogenetic band chr10q23

MYOF NOC3L NUTM2D IFIT5 PLCE1

2.75e-05195825chr10q23
Cytoband1p36.3

GABRD KCNAB2

2.83e-04148221p36.3
CytobandEnsembl 112 genes in cytogenetic band chr18q11

GREB1L TTC39C OSBPL1A

4.88e-0485823chr18q11
Cytoband10q24.32

CUEDC2 NT5C2

8.48e-042482210q24.32
Cytoband18q11.2

GREB1L TTC39C

3.23e-034782218q11.2
CytobandEnsembl 112 genes in cytogenetic band chr10q24

CUEDC2 RRP12 NT5C2

4.79e-03189823chr10q24
CytobandEnsembl 112 genes in cytogenetic band chr15q14

NUTM1 SLC12A6

5.39e-0361822chr15q14
Cytoband2p11.2

USP39 DNAH6

5.91e-03648222p11.2
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRD GABRR3 GABRA4 GABRA6

2.11e-0719514563
GeneFamilyC-type lectin domain family

CLEC18A CLEC18B CLEC18C

3.14e-0447513494
GeneFamilyBasic leucine zipper proteins|BTB domain containing

LZTR1 KLHL15 ZBTB14 KLHL17

5.50e-04134514861
GeneFamilyDyneins, axonemal

DNAH2 DNAH6

1.03e-0317512536
GeneFamilySolute carriers

SLC12A6 SLC9C1 SLC12A4 SLC12A7 SLC29A1

5.00e-03395515752
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 MYOF MGST1 TTC39C OLFM1

1.17e-051608251f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IRGM LZTR1 INPP5K OSBPL1A IFIT5

2.17e-05182825c98da2db197b1531204e116600ff51891e5c17af
ToppCellfacs-Heart-LA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 SLC12A7 ADGRA2 CTSH EPHA5

2.35e-051858251ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCellfacs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 SLC12A7 ADGRA2 CTSH EPHA5

2.35e-05185825b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L PTBP3 SLC9C1 MGST1 PRKAG2

2.35e-05185825a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L PTBP3 ATP8B1 BCAR3 PRKAG2

2.35e-05185825d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH1 VPS13A OLFM1 PRKAG2 DNAH6

2.60e-05189825a75226616340045b581d08429d2e123e041dee55
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH1 VPS13A OLFM1 PRKAG2 DNAH6

2.67e-0519082549e09cdb843b3d889a06a811aa5affae68b25a75
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L IRF6 SLC12A7 ADGRA2 CTSH

2.81e-051928250b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 SQSTM1 SMARCA2 IRF6 SLC29A1

2.95e-051948254d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L MTUS1 ATP8B1 PRKAG2 CTSH

2.95e-051948254579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L PTBP3 MTUS1 PRKAG2 CTSH

2.95e-051948254d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellfacs-Skin-Telogen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 SQSTM1 SMARCA2 IRF6 SLC29A1

2.95e-05194825ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCellfacs-Skin-Telogen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 SQSTM1 SMARCA2 IRF6 SLC29A1

2.95e-05194825bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MGST1 MTUS1 ATP8B1 PRKAG2 CTSH

3.02e-051958253d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L IRF6 SLC12A7 ADGRA2 CTSH

3.10e-05196825e386526332138e636aef2542c11316347a45689c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Fos_(Layer_5a,_IEG+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NUTM1 SPATA16 TMPRSS11F

5.49e-0540823b4c04100180790e1a53a15e8311e40015306c088
DrugPotassium Chloride

SLC12A6 SLC12A4 SLC12A7

8.61e-076813DB00761
Drughafnium oxide

TRAF3IP2 ADGRA2 CTSH RASD2

7.16e-0635814CID000292779
Drug((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid

SLC12A4 SLC12A7

1.25e-052812ctd:C095651
Drugheptachlor epoxide

GABRD MGST1 GABRA4 GABRA6

2.16e-0546814CID000013930
DrugBumetanide

SLC12A6 SLC12A4 SLC12A7

2.35e-0516813ctd:D002034
Drugdihydroxyaflavinine

GABRD GABRA4 GABRA6

2.85e-0517813CID000156857
Drugnocamycin

OLFM1 ADGRA2 RASD2

3.41e-0518813CID003085271
Drugprochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A

MLXIPL MTUS1 SQSTM1 IFIT5 PRKAG2 SLC12A7

4.60e-051818162675_UP
Drugprazepam

MLXIPL GABRA4 GABRA6

5.51e-0521813CID000004890
DrugR 5135

OLFM1 GABRA4 GABRA6

5.51e-0521813CID000119544
Druggeldanamycin; Down 200; 1uM; HL60; HT_HG-U133A

MYOF LZTR1 MTUS1 RRP12 SLC29A1 GABRA4

5.68e-051888166187_DN
Drugphenobarbital quinidine

GABRD GABRA4 GABRA6

6.36e-0522813ctd:C033457
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A

GREB1L MTUS1 INPP5K RRP12 SMARCA2 EPHA5

6.76e-051948164572_DN
Druggamma-Aminobutyric Acid

GABRD GABRR3 GABRA4 GABRA6

7.09e-0562814ctd:D005680
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

IFRD1 THOP1 SQSTM1 INPP5K IFIT5 PRKAG2

7.16e-051968166924_DN
DrugIproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

DOCK5 PTBP3 VPS13A SMARCA2 IFIT5 ZBTB14

7.16e-051968162288_DN
DrugQuinic acid [86-68-0]; Down 200; 19.6uM; HL60; HT_HG-U133A

TRAF3IP2 PHKG2 MYOF MTUS1 SQSTM1 RRP12

7.16e-051968162978_DN
DrugMyricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

MYOF IFRD1 THOP1 SQSTM1 IFIT5 DYNC1H1

7.57e-051988163270_UP
DrugFoliosidine [2520-38-9]; Up 200; 13uM; HL60; HT_HG-U133A

DOCK5 TRAF3IP2 MYOF INPP5K BCAR3 GABRA4

7.78e-051998162201_UP
Drugmethohexital

GABRD GABRA4 GABRA6

8.32e-0524813CID000009034
DiseaseChromosome 1p36 Deletion Syndrome

GABRD KCNAB2

6.69e-055772C1842870
Diseaseepilepsy (implicated_via_orthology)

SLC12A6 SLC12A4 KCNH1 SLC12A7 DYNC1H1

6.93e-05163775DOID:1826 (implicated_via_orthology)
Diseaseglycogen storage disease (is_implicated_in)

PHKG2 PRKAG2

2.39e-049772DOID:2747 (is_implicated_in)
Diseaseresponse to interferon

SPATA16 PLCE1

1.94e-0325772EFO_0007859
Diseaseobsolete_red blood cell distribution width

DOCK5 MLXIPL SQSTM1 VPS13A NT5C2 SMARCA2 PRKAG2 NUTM2F SLC12A7 SLC29A1

2.58e-0313477710EFO_0005192

Protein segments in the cluster

PeptideGeneStartEntry
EAVEDSESGVYMRFM

PRKAG2

251

Q9UGJ0
FMSYRSMFQDVRDAV

NT5C2

191

P49902
TARFMAEAADSYRMN

BCAR3

746

O75815
TAEAASFSDMMDVVY

ADGRA2

451

Q96PE1
RYTEIFMENGYSSMD

EPHA5

981

P54756
TLSASFRTMAEFMDY

AKIP1

81

Q9NQ31
FRTMAEFMDYTSSQC

AKIP1

86

Q9NQ31
NFDMEAFTEMMEAYV

CUEDC2

51

Q9H467
MSTARDETRDGFYME

CHD7

2276

Q9P2D1
RYFSTDMSIGQMEFL

ATG2B

596

Q96BY7
MQAVMSSDYSFAQFR

ATP8B1

916

O43520
MFFEDSIIYTTEMDN

KCTD19

776

Q17RG1
MSNFYEERTTMIAAR

ANAPC1

1

Q9H1A4
SMEEYNTSSTDFTFM

OR2T1

51

O43869
AARSSYFEAMFRSFM

LZTR1

686

Q8N653
EMAEISRIQYEMEYT

MFF

26

Q9GZY8
MTYTAFSDVVMQSEV

MTUS1

241

Q9ULD2
QVMDDEVFMAFASYA

MGST1

6

P10620
NRYDFIMVASAQFSM

IRGM

111

A1A4Y4
EYKSMVDFMNTDNFT

OLFM1

276

Q99784
RMMDIVQDATFVYAT

CES4A

416

Q5XG92
TMEEFADFNTYVAYM

KDM4E

21

B2RXH2
TFENYEMNSFEILMY

KCNH1

86

O95259
VSDVEMEYTMDVFFR

GABRA4

86

P48169
SDVEMEYTMDVFFRQ

GABRA6

71

Q16445
DHISEANMEYTMTVF

GABRD

76

O14764
MYNFTSFAMVLNEVD

OSBPL1A

846

Q9BXW6
RQYMDFTSASQMSDS

GREB1L

1446

Q9C091
SYESSSFMFLVFDLM

PHKG2

96

P15735
SSMEIMEAYSVARQF

KCNAB2

191

Q13303
TSNFDRMIFYEMAER

NUTM1

271

Q86Y26
SMEAVDEMFSSSYIT

ORC1

751

Q13415
FMSFRSLFQDVTDAM

NT5DC4

161

Q86YG4
FVVMSEEMEKVYNSF

DNAH6

3926

Q9C0G6
SISETNMDFTMTFYL

GABRR3

96

A8MPY1
MERDSMFAFAYTDLA

IFIT5

331

Q13325
TQSDYFRIMFTADMR

KLHL15

51

Q96M94
YFHAMFTNEMSESRQ

KLHL17

116

Q6TDP4
MEMSDSETYDFLVFD

DOCK5

681

Q9H7D0
VENDMMVSYSSTSDF

INPP5K

341

Q9BT40
SEMSNRTMTIYFDQV

CBLN2

106

Q8IUK8
FAFEVTQDFMMYRTG

CTSH

251

P09668
ESDFFYEDMESLTQM

IFRD1

301

O00458
AAMVEFYTMSQERFT

DYNC1H1

2771

Q14204
GENYVTMVEMTFVFS

DNAH2

2306

Q9P225
SDISAYTYERTLMME

SLC12A6

981

Q9UHW9
NDISAFTYERTLMME

SLC12A7

916

Q9Y666
VTETFMLAAMAYDRF

OR5D13

111

Q8NGL4
SATELFEAYSMAEMT

NOC3L

731

Q8WTT2
MIYEMFSGDFTRSFD

IRF6

401

O14896
EHMETRNYSAMTEFF

OR13D1

31

Q8NGV5
QHTSNFDRMIFYEMA

NUTM2D

316

Q5VT03
HTSNFDRMIFYEMAE

NUTM2F

266

A1L443
HTSNFDRMIFYEMAA

NUTM2G

266

Q5VZR2
TSLMTIMEDYFAFRN

SMARCA2

1076

P51531
VVFFTTAFDMDTYML

SLC9C1

86

Q4G0N8
NDEYQETMVESTFMY

USP39

376

Q53GS9
FMVSDSNMSFVEFVE

PLCE1

1206

Q9P212
EAMLFTSEIFDMYQQ

MTRF1L

141

Q9UGC7
RCSDTFINEMVIYFM

OR7E24

206

Q6IFN5
DEMGVRYEFVESFMS

SPATA16

131

Q9BXB7
MMDATFSAVYNSFRA

PEX13

146

Q92968
VFFSLRVTNMMFSED

IMPG2

901

Q9BZV3
RFDQMRDMFDDYVRT

MLXIPL

746

Q9NP71
SDISAYTYERTLMME

SLC12A4

916

Q9UP95
EYFAALMTTMEAVES

RRP12

146

Q5JTH9
FFMTATQYFTNRLDM

SLC29A1

31

Q99808
AFSSDEELTMAMSYV

SQSTM1

76

Q13501
MRMFEEDTYNSFVVS

CLDN34

116

H7C241
YSMDTAMEVVKFVNF

TRAF3IP2

416

O43734
MQSRVTFDTMDFIAE

CNBD2

66

Q96M20
FMVSSEADTYYRARM

CLEC18A

311

A5D8T8
FMVSSEADTYYRARM

CLEC18B

311

Q6UXF7
FMVSSEADTYYRARM

CLEC18C

311

Q8NCF0
MEFFISMSETIKYND

ZBTB14

1

O43829
EVFSFKMVSYMDATA

VPS13A

1121

Q96RL7
MMYAPVEFSEAEFSR

TMPRSS11F

1

Q6ZWK6
DSMFEDQMVYTVRYR

PPAT

291

Q06203
SEMFSDSYMSQEIAD

nan

16

Q56UQ5
NTNVDEMFYVLFSMA

RASD2

176

Q96D21
MASEEAAVTMVNYYT

PTBP3

101

O95758
ASFVSFLNAMMTFEE

TTC39C

66

Q8N584
SEFDVEMSMREDVYQ

THOP1

106

P52888
TFTVFAEMYENQALM

MYOF

856

Q9NZM1